| Title Alternative | Vitamin D-resistant rickets/osteomalacia: FGF23-related hypophosphatemic rickets/osteomalacia |
|---|---|
| Author | Fujisawa, Satoshi| Inagaki, Kenichi| Wada, Jun| |
| Keywords | FGF23 くる病 骨軟化症 低リン血症 |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2022-08-01 |
| Volume | volume134 |
| Issue | issue2 |
| Start Page | 92 |
| End Page | 94 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.134.92 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2022 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.134.92 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hada, Yoshiko| Uchida, Haruhito A.| Umebayashi, Ryoko| Yoshida, Masashi| Wada, Jun| |
| Keywords | cilostazol angiotensin II fibrosis osteopontin cAMP-PKA |
| Published Date | 2022-08-13 |
| Publication Title | International Journal Of Molecular Sciences |
| Volume | volume23 |
| Issue | issue16 |
| Publisher | MDPI |
| Start Page | 9065 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 36012328 |
| DOI | 10.3390/ijms23169065 |
| Web of Science KeyUT | 000845679000001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms23169065 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Uchida, Haruhito A.| Takatsuka, Tetsuharu| Hada, Yoshiko| Umebayashi, Ryoko| Takeuchi, Hidemi| Shikata, Kenichi| Subramanian, Venkateswaran| Daugherty, Alan| Wada, Jun| |
| Keywords | edaravone angiotensin II abdominal aortic aneurysm atherosclerosis |
| Published Date | 2022-08-14 |
| Publication Title | Biomolecules |
| Volume | volume12 |
| Issue | issue8 |
| Publisher | MDPI |
| Start Page | 1117 |
| ISSN | 2218-273X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 36009011 |
| DOI | 10.3390/biom12081117 |
| Web of Science KeyUT | 000846165000001 |
| Related Url | isVersionOf https://doi.org/10.3390/biom12081117 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsuoka-Uchiyama, Natsumi| Tsuji, Kenji| Sang, Yizhen| Takahashi, Kensaku| Fukushima, Kazuhiko| Takeuchi, Hidemi| Inagaki, Kenichi| Uchida, Haruhito A.| Kitamura, Shinji| Sugiyama, Hitoshi| Wada, Jun| |
| Published Date | 2022-09-02 |
| Publication Title | Scientific Reports |
| Volume | volume12 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 14999 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 36056164 |
| DOI | 10.1038/s41598-022-19226-0 |
| Web of Science KeyUT | 000849436000046 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-022-19226-0 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Takeuchi, Hidemi| Uchida, Haruhito A.| Katayama, Katsuyoshi| Matsuoka-Uchiyama, Natsumi| Okamoto, Shugo| Onishi, Yasuhiro| Okuyama, Yuka| Umebayashi, Ryoko| Miyaji, Kodai| Kai, Akiko| Matsumoto, Izumi| Taniguchi, Keiko| Yamashita, Fukiko| Emi, Tsutomu| Sugiyama, Hitoshi| Wada, Jun| |
| Keywords | chronic kidney disease specific medical health check-up home-visit type lifestyle intervention CKD exacerbation |
| Published Date | 2022-10-26 |
| Publication Title | Medicina |
| Volume | volume58 |
| Issue | issue11 |
| Publisher | MDPI |
| Start Page | 1529 |
| ISSN | 1010-660X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 36363486 |
| DOI | 10.3390/medicina58111529 |
| Web of Science KeyUT | 000883971300001 |
| Related Url | isVersionOf https://doi.org/10.3390/medicina58111529 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Oda, Kaori| Miyamoto, Satoshi| Kodera, Ryo| Wada, Jun| Shikata, Kenichi| |
| Keywords | Diabetic kidney disease Inflammasomes Suramin |
| Published Date | 2022-10-29 |
| Publication Title | Journal Of Diabetes Investigation |
| Volume | volume14 |
| Issue | issue2 |
| Publisher | Wiley |
| Start Page | 205 |
| End Page | 220 |
| ISSN | 2040-1116 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Authors. |
| File Version | publisher |
| PubMed ID | 36308062 |
| DOI | 10.1111/jdi.13930 |
| Web of Science KeyUT | 000875614000001 |
| Related Url | isVersionOf https://doi.org/10.1111/jdi.13930 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Uchiyama-Matsuoka, Natsumi| Tsuji, Kenji| Uchida, Haruhito A.| Kitamura, Shinji| Itoh, Yoshihiko| Nishiyama, Yuki| Morimoto, Eisaku| Fujisawa, Satoshi| Terasaka, Tomohiro| Hara, Takayuki| Ogura-Ochi, Kanako| Inagaki, Kenichi| Wada, Jun| |
| Keywords | chronic kidney disease masked CKD reversible CKD hyperthyroidism hypothyroidism eGFR |
| Published Date | 2022-11-08 |
| Publication Title | Frontiers In Endocrinology |
| Volume | volume13 |
| Publisher | Frontiers Media SA |
| Start Page | 1048863 |
| ISSN | 1664-2392 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Uchiyama-Matsuoka, Tsuji, Uchida, Kitamura, Itoh, Nishiyama, Morimoto, Fujisawa, Terasaka, Hara, Ogura-Ochi, Inagaki and Wada. |
| File Version | publisher |
| PubMed ID | 36425466 |
| DOI | 10.3389/fendo.2022.1048863 |
| Web of Science KeyUT | 000888307500001 |
| Related Url | isVersionOf https://doi.org/10.3389/fendo.2022.1048863 |
| FullText URL | fulltext20220509-2.pdf |
|---|---|
| Author | Matsumoto, Yoshinori| Dimitriou, Ioannis D.| La Rose, Jose| Lim, Melissa| Camilleri, Susan| Law, Napoleon| Adissu, Hibret A.| Tong, Jiefei| Moran, Michael F.| Chruscinski, Andrzej| He, Fang| Asano, Yosuke| Katsuyama, Takayuki| Sada, Ken-ei| Wada, Jun| Rottapel, Robert| |
| Published Date | 2022-4-1 |
| Publication Title | Journal of Clinical Investigation |
| Volume | volume132 |
| Issue | issue7 |
| Publisher | American Society for Clinical Investigation |
| Start Page | e140869 |
| ISSN | 1558-8238 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022, Matsumoto et al. |
| File Version | publisher |
| PubMed ID | 35274528 |
| DOI | 10.1172/jci140869 |
| Web of Science KeyUT | 000783678600007 |
| Related Url | isVersionOf https://doi.org/10.1172/jci140869 |
| FullText URL | fulltext20220921-3.pdf |
|---|---|
| Author | Uchida, Haruhito A.| Nakajima, Hirofumi| Hashimoto, Masami| Nakamura, Akihiko| Nunoue, Tomokazu| Murakami, Kazuharu| Hosoya, Takeshi| Komoto, Kiichi| Taguchi, Takashi| Akasaka, Takaaki| Shiosakai, Kazuhito| Sugimoto, Kotaro| Wada, Jun| |
| Published Date | 2022-9-7 |
| Publication Title | Advances in Therapy |
| Publisher | Springer Science and Business Media LLC |
| ISSN | 0741-238X |
| NCID | AA10703556 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 36070133 |
| DOI | 10.1007/s12325-022-02294-z |
| Web of Science KeyUT | 000852459600002 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nojima, Ichiro| Wada, Jun| |
| Keywords | CD8 T cells AMPK mTORC OXPHOS autoimmune disease aging cancer |
| Published Date | 2023-01-01 |
| Publication Title | International Journal Of Molecular Sciences |
| Volume | volume24 |
| Issue | issue1 |
| Publisher | MDPI |
| Start Page | 755 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36614197 |
| DOI | 10.3390/ijms24010755 |
| Web of Science KeyUT | 000908631300001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms24010755 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsuoka-Uchiyama, Natsumi| Tsuji, Kenji| Takahashi, Kensaku| Fukushima, Kazuhiko| Takeuchi, Hidemi| Kitamura, Shinji| Inagaki, Kenichi| Uchida, Haruhito A. A.| Wada, Jun| |
| Keywords | hypothyroidism kidney function urinary creatinine excretion |
| Published Date | 2023-02-10 |
| Publication Title | Diagnostics |
| Volume | volume13 |
| Issue | issue4 |
| Publisher | MDPI |
| Start Page | 669 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36832157 |
| DOI | 10.3390/diagnostics13040669 |
| Web of Science KeyUT | 000939117200001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics13040669 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Asano, Yosuke| Matsumoto, Yoshinori| Wada, Jun| Rottapel, Robert| |
| Keywords | E3-ubiquitin ligases ubiquitylation proteasomal degradation osteoimmunology cherubism |
| Published Date | 2023-02-23 |
| Publication Title | Frontiers in Immunology |
| Volume | volume14 |
| Publisher | Frontiers Media |
| Start Page | 1120710 |
| ISSN | 1664-3224 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Asano, Matsumoto, Wada and Rottapel. |
| File Version | publisher |
| PubMed ID | 36911671 |
| DOI | 10.3389/fimmu.2023.1120710 |
| Web of Science KeyUT | 000945836300001 |
| Related Url | isVersionOf https://doi.org/10.3389/fimmu.2023.1120710 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tanaka, Keiko| Sugiyama, Hitoshi| Morinaga, Hiroshi| Kitagawa, Masashi| Kano, Yuzuki| Onishi, Yasuhiro| Mise, Koki| Tanabe, Katsuyuki| Uchida, Haruhito A.| Wada, Jun| |
| Keywords | IgA nephropathy cytokines sCD40L IL-31 proteinuria inflammation interstitial fibrosis |
| Published Date | 2023-03-03 |
| Publication Title | Journal of Clinical Medicine |
| Volume | volume12 |
| Issue | issue5 |
| Publisher | MDPI |
| Start Page | 2023 |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36902810 |
| DOI | 10.3390/jcm12052023 |
| Web of Science KeyUT | 000947139700001 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm12052023 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Onishi, Yasuhiro| Uchida, Haruhito A.| Maeshima, Yohei| Okuyama, Yuka| Otaka, Nozomu| Ujike, Haruyo| Tanaka, Keiko| Takeuchi, Hidemi| Tsuji, Kenji| Kitagawa, Masashi| Tanabe, Katsuyuki| Morinaga, Hiroshi| Kinomura, Masaru| Kitamura, Shinji| Sugiyama, Hitoshi| Ota, Kosuke| Maruyama, Keisuke| Hiramatsu, Makoto| Oshiro, Yoshiyuki| Morioka, Shigeru| Takiue, Keiichi| Omori, Kazuyoshi| Fukushima, Masaki| Gamou, Naoyuki| Hirata, Hiroshi| Sato, Ryosuke| Makino, Hirofumi| Wada, Jun| |
| Keywords | chronic kidney disease (CKD) medical cooperation patient care team OCKD-NET |
| Published Date | 2023-03-26 |
| Publication Title | Journal of Personalized Medicine |
| Volume | volume13 |
| Issue | issue4 |
| Publisher | MDPI |
| Start Page | 582 |
| ISSN | 2075-4426 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 37108968 |
| DOI | 10.3390/jpm13040582 |
| Web of Science KeyUT | 000977705500001 |
| Related Url | isVersionOf https://doi.org/10.3390/jpm13040582 |
| JaLCDOI | 10.18926/AMO/65489 |
|---|---|
| FullText URL | 77_3_243.pdf |
| Author | Shibata, Yusuke| Eguchi, Jun| Wada, Jun| |
| Abstract | Brown adipose tissue (BAT) plays a critical role in metabolic homeostasis. BAT dysfunction is associated with the development of obesity through an imbalance between energy expenditure and energy intake. The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is the master regulator of adipogenesis. However, the roles of PPARγ and thiazolidinediones (TZDs) in the regulation of BAT metabolism remain unclear. TZDs, which are selective PPARγ activators, improve systemic insulin resistance in animals and humans. In the present study, we generated brown adipocyte-specific PPARγ-deficient mice (BATγKO) to examine the in vivo roles of PPARγ and TZDs in BAT metabolism. In electron microscopic examinations, brown adipocyte-specific PPARγ deletion promoted severe whitening of brown fat and morphological alteration of mitochondria. Brown adipocyte-specific PPARγ deletion also reduced mRNA expression of BAT-selective genes. Although there was no difference in energy expenditure between control and BATγKO mice in calorimetry, norepinephrine-induced thermogenesis was impaired in BATγKO mice. Moreover, pioglitazone treatment improved diet-induced insulin resistance in the control mice but not in the BATγKO mice. These findings suggest that BAT PPARγ is necessary for the maintenance of brown adipocyte function and for the insulin-sensitizing action of TZDs. |
| Keywords | PPARγ brown adipose tissue thiazolidinediones |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 243 |
| End Page | 254 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357625 |
| Web of Science KeyUT | 001026279600002 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kurooka, Naoko| Eguchi, Jun| Wada, Jun| |
| Keywords | Dibaetes GPIHBP1 Lipoprotein lipase |
| Published Date | 2023-07-13 |
| Publication Title | Journal of Diabetes Investigation |
| Volume | volume14 |
| Issue | issue10 |
| Publisher | Wiley |
| Start Page | 1148 |
| End Page | 1156 |
| ISSN | 2040-1116 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Authors. |
| File Version | publisher |
| PubMed ID | 37448184 |
| DOI | 10.1111/jdi.14056 |
| Web of Science KeyUT | 001024517600001 |
| Related Url | isVersionOf https://doi.org/10.1111/jdi.14056 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsuji, Kenji| Okuyama, Yuka| Asano, Yosuke| Yamaoka, Kimitomo| Kitamura, Shinji| Wada, Jun| |
| Keywords | ANCA-associated vasculitis Sjogren's syndrome sarcoidosis monoclonal gammopathy of undetermined significance |
| Published Date | 2023-08-01 |
| Publication Title | Internal Medicine |
| Volume | volume62 |
| Issue | issue15 |
| Publisher | The Japanese Society of Internal Medicine |
| Start Page | 2215 |
| End Page | 2221 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 36450474 |
| DOI | 10.2169/internalmedicine.0966-22 |
| Web of Science KeyUT | 001045161600001 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.0966-22 |
| Title Alternative | Current findings on familial hypobetalipoproteinemia |
|---|---|
| Author | Eguchi, Jun| Wada, Jun| |
| Keywords | 低脂血症 家族性低βリポタンパク血症 無βリポタンパク血症 カイロミクロン停滞病 |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2023-08-01 |
| Volume | volume135 |
| Issue | issue2 |
| Start Page | 81 |
| End Page | 84 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.135.81 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2023 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.135.81 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsuji, Kenji| Nakanoh, Hiroyuki| Fukushima, Kazuhiko| Kitamura, Shinji| Wada, Jun| |
| Keywords | microRNA acute kidney injury biomarker mesenchymal stem cell |
| Published Date | 2023-09-09 |
| Publication Title | Diagnostics |
| Volume | volume13 |
| Issue | issue18 |
| Publisher | MDPI |
| Start Page | 2893 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 37761260 |
| DOI | 10.3390/diagnostics13182893 |
| Web of Science KeyUT | 001119215900001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics13182893 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sang, Yizhen| Tsuji, Kenji| Nakanoh, Hiroyuki| Fukushima, Kazuhiko| Kitamura, Shinji| Wada, Jun| |
| Keywords | semaphorin 3A neuropilin-1 podocyte diabetic nephropathy acute kidney injury chronic kidney injury lupus nephritis fibrosis apoptosis inflammation |
| Published Date | 2023-09-25 |
| Publication Title | Diagnostics |
| Volume | volume13 |
| Issue | issue19 |
| Publisher | MDPI |
| Start Page | 3038 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 37835781 |
| DOI | 10.3390/diagnostics13193038 |
| Web of Science KeyUT | 001083705600001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics13193038 |
