| FullText URL | fulltext20220921-3.pdf |
|---|---|
| Author | Uchida, Haruhito A.| Nakajima, Hirofumi| Hashimoto, Masami| Nakamura, Akihiko| Nunoue, Tomokazu| Murakami, Kazuharu| Hosoya, Takeshi| Komoto, Kiichi| Taguchi, Takashi| Akasaka, Takaaki| Shiosakai, Kazuhito| Sugimoto, Kotaro| Wada, Jun| |
| Published Date | 2022-9-7 |
| Publication Title | Advances in Therapy |
| Publisher | Springer Science and Business Media LLC |
| ISSN | 0741-238X |
| NCID | AA10703556 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 36070133 |
| DOI | 10.1007/s12325-022-02294-z |
| Web of Science KeyUT | 000852459600002 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Uchida, Haruhito A.| Takatsuka, Tetsuharu| Hada, Yoshiko| Umebayashi, Ryoko| Takeuchi, Hidemi| Shikata, Kenichi| Subramanian, Venkateswaran| Daugherty, Alan| Wada, Jun| |
| Keywords | edaravone angiotensin II abdominal aortic aneurysm atherosclerosis |
| Published Date | 2022-08-14 |
| Publication Title | Biomolecules |
| Volume | volume12 |
| Issue | issue8 |
| Publisher | MDPI |
| Start Page | 1117 |
| ISSN | 2218-273X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 36009011 |
| DOI | 10.3390/biom12081117 |
| Web of Science KeyUT | 000846165000001 |
| Related Url | isVersionOf https://doi.org/10.3390/biom12081117 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Asano, Yosuke| Matsumoto, Yoshinori| Wada, Jun| Rottapel, Robert| |
| Keywords | E3-ubiquitin ligases ubiquitylation proteasomal degradation osteoimmunology cherubism |
| Published Date | 2023-02-23 |
| Publication Title | Frontiers in Immunology |
| Volume | volume14 |
| Publisher | Frontiers Media |
| Start Page | 1120710 |
| ISSN | 1664-3224 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Asano, Matsumoto, Wada and Rottapel. |
| File Version | publisher |
| PubMed ID | 36911671 |
| DOI | 10.3389/fimmu.2023.1120710 |
| Web of Science KeyUT | 000945836300001 |
| Related Url | isVersionOf https://doi.org/10.3389/fimmu.2023.1120710 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nojima, Ichiro| Eikawa, Shingo| Tomonobu, Nahoko| Hada, Yoshiko| Kajitani, Nobuo| Teshigawara, Sanae| Miyamoto, Satoshi| Tone, Atsuhito| Uchida, Haruhito A.| Nakatsuka, Atsuko| Eguchi, Jun| Shikata, Kenichi| Udono, Heiichiro| Wada, Jun| |
| Keywords | Cytokines Diabetes Endocrine system and metabolic diseases Immunology Tumour immunology |
| Published Date | 2020-09-10 |
| Publication Title | Scientific Reports |
| Volume | volume10 |
| Issue | issue1 |
| Publisher | Nature Research |
| Start Page | 14928 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2020 |
| File Version | publisher |
| PubMed ID | 32913271 |
| DOI | 10.1038/s41598-020-71946-3 |
| Web of Science KeyUT | 000571915100049 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-020-71946-3 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | La, The Mon| Tachibana, Hiromi| Li, Shun-Ai| Abe, Tadashi| Seiriki, Sayaka| Nagaoka, Hikaru| Takashima, Eizo| Takeda, Tetsuya| Ogawa, Daisuke| Makino, Shin-Ichi| Asanuma, Katsuhiko| Watanabe, Masami| Tian, Xuefei| Ishibe, Shuta| Sakane, Ayuko| Sasaki, Takuya| Wada, Jun| Takei, Kohji| Yamada, Hiroshi| |
| Keywords | dynamin microtubules podocyte primary process |
| Published Date | 2020-10-17 |
| Publication Title | FASEB Journal |
| Volume | volume34 |
| Issue | issue12 |
| Publisher | Wiley |
| Start Page | 16449 |
| End Page | 16463 |
| ISSN | 0892-6638 |
| NCID | AA1066874X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Authors. |
| File Version | publisher |
| PubMed ID | 33070431 |
| NAID | 120006900792 |
| DOI | 10.1096/fj.202001240RR |
| Web of Science KeyUT | 000581167100001 |
| Related Url | isVersionOf https://doi.org/10.1096/fj.202001240RR |
| FullText URL | fulltext20220208-1.pdf |
|---|---|
| Author | Onishi, Yasuhiro| Mise, Koki| Kawakita, Chieko| Uchida, Haruhito A.| Sugiyama, Hitoshi| Sugawara, Ryosuke| Yamaguchi, Satoshi| Yoshida, Michihiro| Mitsuhashi, Toshiharu| Yamada, Masao| Hirabayashi, Jun| Wada, Jun| |
| Keywords | Glomerulonephritis IgA nephropathy Diagnostic biomarkers Lectins Glycomics |
| Note | This is an Accepted Manuscript published by S. Karger AG.| |
| Published Date | 2021-12-29 |
| Publication Title | American Journal of Nephrology |
| Volume | volume53 |
| Issue | issue1 |
| Publisher | S. Karger AG |
| Start Page | 10 |
| End Page | 20 |
| ISSN | 0250-8095 |
| NCID | AA10424676 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 S. Karger AG, Basel |
| File Version | author |
| PubMed ID | 34965524 |
| DOI | 10.1159/000520998 |
| Web of Science KeyUT | 000747743400001 |
| Related Url | isVersionOf https://doi.org/10.1159/000520998 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hiramatsu-Asano, Sumie| Sunahori-Watanabe, Katsue| Zeggar, Sonia| Katsuyama, Eri| Mukai, Tomoyuki| Morita, Yoshitaka| Wada, Jun| |
| Keywords | miR-223-3p S1pr1 S1PR1(+)CD4(+) T cells lupus nephritis MRL/MpJ-Faslpr/J mice |
| Published Date | 2021-01-26 |
| Publication Title | Frontiers in Immunology |
| Volume | volume11 |
| Publisher | Frontiers Media |
| Start Page | 616141 |
| ISSN | 1664-3224 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Hiramatsu-Asano, Sunahori-Watanabe, Zeggar, Katsuyama, Mukai, Morita and Wada. |
| File Version | publisher |
| PubMed ID | 33574820 |
| DOI | 10.3389/fimmu.2020.616141 |
| Web of Science KeyUT | 000616095500001 |
| Related Url | isVersionOf https://doi.org/10.3389/fimmu.2020.616141 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kitamura, Shinji| Takahashi, Kensaku| Sang, Yizhen| Fukushima, Kazuhiko| Tsuji, Kenji| Wada, Jun| |
| Keywords | immunofluorescent image renal pathology artificial intelligence deep learning diabetic nephropathy |
| Published Date | 2020-07-09 |
| Publication Title | Diagnostics |
| Volume | volume10 |
| Issue | issue7 |
| Publisher | MDPI |
| Start Page | 466 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by the authors. |
| File Version | publisher |
| PubMed ID | 32660112 |
| DOI | 10.3390/diagnostics10070466 |
| Web of Science KeyUT | 000557155500001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics10070466 |
| Author | Sugiyama, Koichi| Sada, Ken-ei| Kurosawa, Michiko| Wada, Jun| Makino, Hirofumi| |
|---|---|
| Published Date | 2013-02 |
| Publication Title | Clinical and Experimental Nephrology |
| Volume | volume17 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/56871 |
|---|---|
| FullText URL | 73_3_269.pdf |
| Author | Tsuboi, Ichiro| Araki, Motoo| Fujiwara, Hiroyasu| Iguchi, Toshihiro| Hiraki, Takao| Arichi, Naoko| Kawamura, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Sako, Tomoko| Takamoto, Atsushi| Wada, Koichiro| Kobayashi, Yasuyuki| Watanabe, Toyohiko| Yanai, Hiroyuki| Kitagawa, Masashi| Tanabe, Katsuyuki| Sugiyama, Hitoshi| Wada, Jun| Shiina, Hiroaki| Kanazawa, Susumu| Nasu, Yasutomo| |
| Abstract | Nephron-sparing treatment should be offered whenever possible to avoid dialysis in allograph cases. Cryoablation is a new treatment option for treating small-sized renal cell cancer (RCCs). We report a case of RCC arising in a kidney allograft treated by cryoablation. To our knowledge, this is the first case in Asia of RCC in a renal allograft treated using cryoablation. Contrast-enhanced CT-guided percutaneous renal needle biopsy and cryoablation were used to identify the RCC, which could not be identified by other techniques. The postoperative course was uneventful. Contrast-enhanced CT also showed no recurrence or metastases at the 6-month follow-up. |
| Keywords | cryoablation partial nephrectomy renal cell carcinoma renal allograft renal transplantation |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 269 |
| End Page | 272 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235976 |
| JaLCDOI | 10.18926/AMO/32883 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Miyatake, Nobuyuki| Wada, Jun| Saito, Takeshi| Nishikawa, Hidetaka| Matsumoto, Sumiko| Miyachi, Motohiro| Makino, Hirofumi| Numata, Takeyuki| |
| Abstract | We compared muscle strength between Japanese men with and without metabolic syndrome. We used data for 323 Japanese men with metabolic syndrome and 893 Japanese men without the syndrome. Metabolic syndrome was defined by a new criterion in Japan, and the parameters for muscle strength, i.e. grip strength, leg strength were measured. Leg strength was found to be significantly higher in subjects with metabolic syndrome than in those without, while muscle strength per body weight was significantly lower in subjects with the syndrome. Lower muscle strength per body weight may be one of the characteristic features in subjects with metabolic syndrome. |
| Keywords | metabolic syndrome grip strength leg strength |
| Amo Type | Short Communication |
| Publication Title | Acta Medica Okayama |
| Published Date | 2007-04 |
| Volume | volume61 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 89 |
| End Page | 102 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 17471310 |
| Web of Science KeyUT | 000245875600007 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsuji, Kenji| Okuyama, Yuka| Asano, Yosuke| Yamaoka, Kimitomo| Kitamura, Shinji| Wada, Jun| |
| Keywords | ANCA-associated vasculitis Sjogren's syndrome sarcoidosis monoclonal gammopathy of undetermined significance |
| Published Date | 2023-08-01 |
| Publication Title | Internal Medicine |
| Volume | volume62 |
| Issue | issue15 |
| Publisher | The Japanese Society of Internal Medicine |
| Start Page | 2215 |
| End Page | 2221 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 36450474 |
| DOI | 10.2169/internalmedicine.0966-22 |
| Web of Science KeyUT | 001045161600001 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.0966-22 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hada, Yoshiko| Uchida, Haruhito A.| Umebayashi, Ryoko| Yoshida, Masashi| Wada, Jun| |
| Keywords | cilostazol angiotensin II fibrosis osteopontin cAMP-PKA |
| Published Date | 2022-08-13 |
| Publication Title | International Journal Of Molecular Sciences |
| Volume | volume23 |
| Issue | issue16 |
| Publisher | MDPI |
| Start Page | 9065 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 36012328 |
| DOI | 10.3390/ijms23169065 |
| Web of Science KeyUT | 000845679000001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms23169065 |
| JaLCDOI | 10.18926/AMO/50405 |
|---|---|
| FullText URL | 67_3_129.pdf |
| Author | Nakatsuka, Atsuko| Wada, Jun| Makino, Hirofumi| |
| Abstract | In recent years, many researchers have emphasized the importance of metabolic syndrome based on its increasing prevalence and its adverse prognosis due to associated chronic vascular complications. Upstream of a cluster of metabolic and vascular disorders is the accumulation of visceral adipose tissue, which plays a central role in the pathophysiology. In the accumulation of adipose tissues, cell cycle regulation is tightly linked to cellular processes such as proliferation, hypertrophy and apoptosis. In addition, various cell cycle abnormalities have also been observed in other tissues, such as kidneys and the cardiovascular system, and they are critically involved in the progression of disease. Here, we discuss cell cycle abnormalities in metabolic syndrome in various tissues. Furthermore, we describe the role of nuclear receptors in cell growth and survival, and glucose and lipid metabolism in the whole body. Therapeutic strategies for modulating various cell cycles in metabolic disorders by targeting nuclear receptors may overcome obesity and its chronic vascular complications in the future. |
| Keywords | nuclear receptor cell cycle metabolic syndrome diabetic nephropathy |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-06 |
| Volume | volume67 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 129 |
| End Page | 134 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23804135 |
| Web of Science KeyUT | 000320747900001 |
| FullText URL | JCR25_4_45.pdf Fig.pdf |
|---|---|
| Author | Motokura, Yumi| Watanabe, Haruki| Yamamura, Yuriko| Kano, Yuzuki| Matsumoto, Yoshinori| Kawabata, Tomoko| Sada, Ken-ei| Wada, Jun| |
| Published Date | 2019-06 |
| Publication Title | Journal of Clinical Rheumatology |
| Volume | volume25 |
| Issue | issue4 |
| Publisher | Lippincott, Williams & Wilkins |
| Start Page | 45 |
| End Page | 47 |
| ISSN | 1076-1608 |
| NCID | AA11016642 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 29470260 |
| DOI | 10.1097/RHU.0000000000000723 |
| Web of Science KeyUT | 000470908400007 |
| Related Url | isVersionOf https://doi.org/10.1097/RHU.0000000000000723 |
| JaLCDOI | 10.18926/AMO/65489 |
|---|---|
| FullText URL | 77_3_243.pdf |
| Author | Shibata, Yusuke| Eguchi, Jun| Wada, Jun| |
| Abstract | Brown adipose tissue (BAT) plays a critical role in metabolic homeostasis. BAT dysfunction is associated with the development of obesity through an imbalance between energy expenditure and energy intake. The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is the master regulator of adipogenesis. However, the roles of PPARγ and thiazolidinediones (TZDs) in the regulation of BAT metabolism remain unclear. TZDs, which are selective PPARγ activators, improve systemic insulin resistance in animals and humans. In the present study, we generated brown adipocyte-specific PPARγ-deficient mice (BATγKO) to examine the in vivo roles of PPARγ and TZDs in BAT metabolism. In electron microscopic examinations, brown adipocyte-specific PPARγ deletion promoted severe whitening of brown fat and morphological alteration of mitochondria. Brown adipocyte-specific PPARγ deletion also reduced mRNA expression of BAT-selective genes. Although there was no difference in energy expenditure between control and BATγKO mice in calorimetry, norepinephrine-induced thermogenesis was impaired in BATγKO mice. Moreover, pioglitazone treatment improved diet-induced insulin resistance in the control mice but not in the BATγKO mice. These findings suggest that BAT PPARγ is necessary for the maintenance of brown adipocyte function and for the insulin-sensitizing action of TZDs. |
| Keywords | PPARγ brown adipose tissue thiazolidinediones |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 243 |
| End Page | 254 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357625 |
| Web of Science KeyUT | 001026279600002 |
| Author | Katayama, Akihiro| Nakatsuka, Atsuko| Eguchi, Jun| Murakami, Kazutoshi| Teshigawara, Sanae| Kanzaki, Motoko| Nunoue, Tomokazu| Hida, Kazuyuki| Wada, Nozomu| Yasunaka, Tetsuya| Ikeda, Fusao| Takaki, Akinobu| Yamamoto, Kazuhide| Kiyonari, Hiroshi| Makino, Hirofumi| Wada, Jun| |
|---|---|
| Published Date | 2015 |
| Publication Title | Scientific reports |
| Volume | volume5 |
| Content Type | Journal Article |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Miyawaki, Yoshia| Shimizu, Sayaka| Ogawa, Yusuke| Sada, Ken-Ei| Katayama, Yukitoshi| Asano, Yosuke| Hayashi, Keigo| Yamamura, Yuriko| Hiramatsu-Asano, Sumie| Ohashi, Keiji| Morishita, Michiko| Watanabe, Haruki| Takano-Narazaki, Mariko| Matsumoto, Yoshinori| Yajima, Nobuyuki| Yoshimi, Ryusuke| Shimojima, Yasuhiro| Ohno, Shigeru| Kajiyama, Hiroshi| Ichinose, Kunihiro| Sato, Shuzo| Fujiwara, Michio| Yamazaki, Hajime| Yamamoto, Yosuke| Wada, Jun| Fukuhara, Shunichi| |
| Keywords | Systemic lupus erythematosus Glucocorticoid Emotional health Patient-reported outcome Depression Anxiety Cross-sectional study |
| Published Date | 2021-03-10 |
| Publication Title | Arthritis Research & Therapy |
| Volume | volume23 |
| Issue | issue1 |
| Publisher | BMC |
| ISSN | 1478-6354 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). 2021 |
| File Version | publisher |
| PubMed ID | 33691746 |
| NAID | 120007019117 |
| DOI | 10.1186/s13075-021-02466-2 |
| Web of Science KeyUT | 000627856600002 |
| Related Url | isVersionOf https://doi.org/10.1186/s13075-021-02466-2 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Katsuyama, Eri| Miyawaki, Yoshia| Sada, Ken-Ei| Asano, Yosuke| Hayashi, Keigo| Yamamura, Yuriko| Hiramatsu-Asano, Sumie| Morishita, Michiko| Ohashi, Keiji| Watanabe, Haruki| Katsuyama, Takayuki| Narazaki, Mariko| Matsumoto, Yoshinori| Wada, Jun| |
| Keywords | Lupus nephritis Active lesions Chronic lesions Urinary protein Serum creatinine |
| Published Date | 2020-06-01 |
| Publication Title | BMC Nephrology |
| Volume | volume21 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 208 |
| ISSN | 1471-2369 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). 2020 |
| File Version | publisher |
| PubMed ID | 32487161 |
| DOI | 10.1186/s12882-020-01868-9 |
| Web of Science KeyUT | 000538054600002 |
| Related Url | isVersionOf https://doi.org/10.1186/s12882-020-01868-9 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsuchida-Nishiwaki, Mariko| Uchida, Haruhito A.| Takeuchi, Hidemi| Nishiwaki, Noriyuki| Maeshima, Yohei| Saito, Chie| Sugiyama, Hitoshi| Wada, Jun| Narita, Ichiei| Watanabe, Tsuyoshi| Matsuo, Seiichi| Makino, Hirofumi| Hishida, Akira| Yamagata, Kunihiro| |
| Published Date | 2021-07-22 |
| Publication Title | Scientific Reports |
| Volume | volume11 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 14990 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021 |
| File Version | publisher |
| PubMed ID | 34294784 |
| DOI | 10.1038/s41598-021-94467-z |
| Web of Science KeyUT | 000682802200023 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-021-94467-z |
