FullText URL | fulltext.pdf |
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Author | Uotani, Koji| Tazawa, Hiroshi| Hasei, Joe| Fujiwara, Tomohiro| Yoshida, Aki| Yamakawa, Yasuaki| Omori, Toshinori| Sugiu, Kazuhisa| Komatsubara, Tadashi| Kondo, Hiroya| Morita, Takuya| Kiyono, Masahiro| Yokoo, Suguru| Hata, Toshiaki| Kunisada, Toshiyuki| Takeda, Ken| Urata, Yasuo| Fujiwara, Toshiyoshi| Ozaki, Toshifumi| |
Published Date | 2024-02-20 |
Publication Title | PLoS ONE |
Volume | volume19 |
Issue | issue2 |
Publisher | Public Library of Science |
Start Page | e0298292 |
ISSN | 1932-6203 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 Uotani et al. |
File Version | publisher |
PubMed ID | 38377118 |
DOI | 10.1371/journal.pone.0298292 |
Web of Science KeyUT | 001176939600021 |
Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0298292 |
Author | Shigeyasu, Kunitoshi| Tazawa, Hiroshi| Hashimoto, Yuuri| Mori, Yoshiko| Nishizaki, Masahiko| Kishimoto, Hiroyuki| Nagasaka, Takeshi| Kuroda, Shinji| Urata, Yasuo| Goel, Ajay| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
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Published Date | 2014-05-28 |
Publication Title | Gut |
Content Type | Journal Article |
FullText URL | fulltext.pdf |
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Author | Katsube, Ryoichi| Noma, Kazuhiro| Ohara, Toshiaki| Nishiwaki, Noriyuki| Kobayashi, Teruki| Komoto, Satoshi| Sato, Hiroaki| Kashima, Hajime| Kato, Takuya| Kikuchi, Satoru| Tazawa, Hiroshi| Kagawa, Shunsuke| Shirakawa, Yasuhiro| Kobayashi, Hisataka| Fujiwara, Toshiyoshi| |
Published Date | 2021-01-18 |
Publication Title | Scientific Reports |
Volume | volume11 |
Issue | issue1 |
Publisher | Nature Research |
Start Page | 1693 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2021 |
File Version | publisher |
PubMed ID | 33462372 |
DOI | 10.1038/s41598-021-81465-4 |
Web of Science KeyUT | 000612156600008 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-021-81465-4 |
FullText URL | fulltext.pdf |
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Author | Tani, Yuma| Sato, Hiroki| Yoshida, Ryuichi| Yasui, Kazuya| Umeda, Yuzo| Yoshida, Kazuhiro| Fuji, Tomokazu| Kumano, Kenjiro| Takagi, Kosei| Kagoura, Masaaki| Yagi, Takahito| Fujiwara, Toshiyoshi| |
Keywords | Hepatocellular carcinoma Peritoneal dissemination Indocyanine green fluorescence |
Published Date | 2022-06-06 |
Publication Title | Journal Of Medical Case Reports |
Volume | volume16 |
Issue | issue1 |
Publisher | BMC |
Start Page | 222 |
ISSN | 1752-1947 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2022. |
File Version | publisher |
PubMed ID | 35659738 |
DOI | 10.1186/s13256-022-03440-5 |
Web of Science KeyUT | 000807221800001 |
Related Url | isVersionOf https://doi.org/10.1186/s13256-022-03440-5 |
FullText URL | fulltext.pdf |
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Author | Yano, Shuya| Tazawa, Hiroshi| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| Hoffman, Robert M.| |
Keywords | cell cycle fluorescent proteins FUCCI imaging targeted cancer therapy quiescent cancer cells decoy chemotherapy |
Published Date | 2020-09-17 |
Publication Title | Cancers |
Volume | volume12 |
Issue | issue9 |
Publisher | MDPI |
Start Page | 2655 |
ISSN | 2072-6694 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32957652 |
DOI | 10.3390/cancers12092655 |
Web of Science KeyUT | 000580315800001 |
Related Url | isVersionOf https://doi.org/10.3390/cancers12092655 |
FullText URL | fulltext.pdf |
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Author | Ito, Atene| Kagawa, Shunsuke| Sakamoto, Shuichi| Kuwada, Kazuya| Kajioka, Hiroki| Yoshimoto, Masashi| Kikuchi, Satoru| Kuroda, Shinji| Yoshida, Ryuichi| Tazawa, Hiroshi| Fujiwara, Toshiyoshi| |
Keywords | Extracellular vesicles Gastric cancer Tumor-associated macrophages Tumor microenvironment |
Published Date | 2021-01-28 |
Publication Title | BMC Cancer |
Volume | volume21 |
Issue | issue1 |
Publisher | BMC |
Start Page | 102 |
ISSN | 1471-2407 |
NCID | AA12034763 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s). 2021 |
File Version | publisher |
PubMed ID | 33509150 |
DOI | 10.1186/s12885-021-07816-6 |
Web of Science KeyUT | 000615987400002 |
Related Url | isVersionOf https://doi.org/10.1186/s12885-021-07816-6 |
JaLCDOI | 10.18926/AMO/46628 |
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FullText URL | 65_3_169.pdf |
Author | Takeda, Masanori| Nagasaka, Takeshi| Dong-Sheng, Sun| Nishie, Hiroyuki| Oka, Tetsuhiro| Yamada, Eiji| Mori, Yoshiko| Shigeyasu, Kunitoshi| Morikawa, Tatsuya| Mizobuchi, Satoshi| Fujiwara, Toshiyoshi| |
Abstract | Secreted frizzled-related protein 2, (SFRP2) is a Wnt inhibitor whose promoter CpGs were recently found to be methylated at high frequency in colorectal cancers (CRCs). We hypothesized that the pattern of SFRP2 methylation may differ throughout the promoter during progressive tumorigenesis. Using combined bisulfite restriction analysis (COBRA), two methylation-sensitive regions (Regions A and B) of the SFRP2 promoter were investigated in 569 specimens of colorectal tissue:222 CRCs, 103 adenomatous polyps (APs), 208 normal colonic mucosa from CRC patients (N-Cs), and 36 normal colonic mucosa from subjects with no evidence of colorectal neoplasia at colonoscopy (N-Ns). Extensive (including both Regions A and B) and partial (either Region A or B) SFRP2 methylation levels were found in 61.7% and 24.8% of CRCs, 8.7% and 37.9% of APs, 3.9% and 39.9% of N-Cs, and 0% and 30.6% of N-Ns, respectively. Extensive methylation of the SFRP2 promoter was present primarily in CRCs, while partial methylation was common in APs. Whereas APs with the KRAS mutant showed no correlation to any pattern of SFRP2 methylation, extensive methylation of the SFRP2 promoter was significantly associated with KRAS mutant CRCs (p<.0001), suggesting that genetic alteration in the RAS-RAF pathway might precede the spread of CpG methylation through the SFRP2 promoter, which is observed in over 60% of advanced colorectal tumors. |
Keywords | BRAF/KRAS mutations promoter methylation colorectal cancer |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2011-06 |
Volume | volume65 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 169 |
End Page | 177 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 21709714 |
Web of Science KeyUT | 000292017500003 |
Author | Itoh, Mitsuya| Iwamoto, Takayuki| Matsuoka, Junji| Nogami, Tomohiro| Motoki, Takayuki| Shien, Tadahiko| Taira, Naruto| Niikura, Naoki| Hayashi, Naoki| Ohtani, Shoichiro| Higaki, Kenji| Fujiwara, Toshiyoshi| Doihara, Hiroyoshi| Symmans, W. Fraser| Pusztai, Lajos| |
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Published Date | 2014-01 |
Publication Title | Breast Cancer Research and Treatment |
Volume | volume143 |
Issue | issue2 |
Content Type | Journal Article |
FullText URL | fulltext.pdf |
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Author | Kikuchi, Satoru| Matsusaki, Takashi| Mitsuhashi, Toshiharu| Kuroda, Shinji| Kashima, Hajime| Takata, Nobuo| Mitsui, Ema| Kakiuchi, Yoshihiko| Noma, Kazuhiro| Umeda, Yuzo| Morimatsu, Hiroshi| Fujiwara, Toshiyoshi| |
Published Date | 2024-01-18 |
Publication Title | BJS Open |
Volume | volume8 |
Issue | issue1 |
Publisher | Oxford University Press |
Start Page | zrad161 |
ISSN | 2474-9842 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2024. |
File Version | publisher |
PubMed ID | 38242571 |
DOI | 10.1093/bjsopen/zrad161 |
Web of Science KeyUT | 001148373800007 |
Related Url | isVersionOf https://doi.org/10.1093/bjsopen/zrad161 |
FullText URL | fulltext.pdf |
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Author | Tanimoto, Terutaka| Tazawa, Hiroshi| Ieda, Takeshi| Nouso, Hiroshi| Tani, Morimichi| Oyama, Takanori| Urata, Yasuo| Kagawa, Shunsuke| Noda, Takuo| Fujiwara, Toshiyoshi| |
Keywords | neuroblastoma MYCN hTERT adenovirus E2F1 |
Published Date | 2020-09-25 |
Publication Title | Molecular Therapy - Oncolytics |
Volume | volume18 |
Publisher | Cell Press |
Start Page | 14 |
End Page | 23 |
ISSN | 2372-7705 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Author(s). |
File Version | publisher |
PubMed ID | 32637577 |
DOI | 10.1016/j.omto.2020.05.015 |
Web of Science KeyUT | 000575168700002 |
Related Url | isVersionOf https://doi.org/10.1016/j.omto.2020.05.015 |
FullText URL | fulltext.pdf |
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Author | Kojima, Toru| Umeda, Yuzo| Fuji, Tomokazu| Niguma, Takefumi| Satoh, Daisuke| Endo, Yoshikatsu| Sui, Kenta| Inagaki, Masaru| Oishi, Masahiro| Ota, Tetsuya| Hioki, Katsuyoshi| Matsuda, Tadakazu| Aoki, Hideki| Hirai, Ryuji| Kimura, Masashi| Yagi, Takahito| Fujiwara, Toshiyoshi| |
Published Date | 2020-09-03 |
Publication Title | PLOS ONE |
Volume | volume15 |
Issue | issue9 |
Publisher | PUBLIC LIBRARY SCIENCE |
Start Page | e0238392 |
ISSN | 1932-6203 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 Kojima et al. |
File Version | publisher |
PubMed ID | 32881910 |
DOI | 10.1371/journal.pone.0238392 |
Web of Science KeyUT | 000571063300054 |
Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0238392 |
FullText URL | fulltext20210608-1.pdf highlights20210608-1.pdf figure20210608-1.pdf table20210608-1.pdf supplement20210608-1.pdf |
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Author | Kuroda, Shinji| Kikuchi, Satoru| Kakiuchi, Yoshihiko| Watanabe, Megumi| Kuwada, Kazuya| Tsumura, Tomoko| Nishizaki, Masahiko| Kagawa, Shunsuke| Hinotsu, Shiro| Fujiwara, Toshiyoshi| |
Note | This is an Accepted Manuscript of an article published by Elsevier BV. © 2021 IJS Publishing Group Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.ijsu.2021.105946] . | |
Published Date | 2021-5 |
Publication Title | International Journal of Surgery |
Volume | volume89 |
Publisher | Elsevier BV |
Start Page | 105946 |
ISSN | 1743-9191 |
NCID | AA12063080 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 IJS Publishing Group Ltd. |
File Version | author |
PubMed ID | 33892160 |
DOI | 10.1016/j.ijsu.2021.105946 |
Web of Science KeyUT | 000651625600016 |
Related Url | isVersionOf https://doi.org/10.1016/j.ijsu.2021.105946 |
FullText URL | fulltext20221020-1.pdf figure20221020-1.pdf table20221020-1.pdf ASO_Takata_Supplementary.pdf |
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Author | Takata, Nobuo| Kikuchi, Satoru| Kuroda, Shinji| Tanabe, Shunsuke| Maeda, Naoaki| Noma, Kazuhiro| Takahashi, Ayako| Umeda, Yuzo| Shikata, Kenichi| Ozaki, Kazuhide| Fujiwara, Toshiyoshi| |
Keywords | Gastric cancer Gastrectomy Body weight loss Skeletal muscle loss Nutritional counseling |
Note | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1245/s10434-022-12572-3| This fulltext is available in Sep. 2023.| |
Published Date | 2022-09-25 |
Publication Title | Annals of Surgical Oncology |
Volume | volume30 |
Issue | issue2 |
Publisher | Springer Science and Business Media LLC |
Start Page | 1110 |
End Page | 1118 |
ISSN | 1068-9265 |
NCID | AA11016573 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Society of Surgical Oncology 2022 |
File Version | author |
PubMed ID | 36161371 |
DOI | 10.1245/s10434-022-12572-3 |
Web of Science KeyUT | 000858651900003 |
Related Url | isVersionOf https://doi.org/10.1245/s10434-022-12572-3 |
FullText URL | fulltext.pdf |
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Author | Sato, Hiroaki| Noma, Kazuhiro| Ohara, Toshiaki| Kawasaki, Kento| Akai, Masaaki| Kobayashi, Teruki| Nishiwaki, Noriyuki| Narusaka, Toru| Komoto, Satoshi| Kashima, Hajime| Katsura, Yuki| Kato, Takuya| Kikuchi, Satoru| Tazawa, Hiroshi| Kagawa, Shunsuke| Shirakawa, Yasuhiro| Kobayashi, Hisataka| Fujiwara, Toshiyoshi| |
Published Date | 2022-11-23 |
Publication Title | Scientific Reports |
Volume | volume12 |
Issue | issue1 |
Publisher | Nature Portfolio |
Start Page | 20152 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2022 |
File Version | publisher |
PubMed ID | 36418422 |
DOI | 10.1038/s41598-022-24313-3 |
Web of Science KeyUT | 000887936300054 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-022-24313-3 |
Author | Yoshimoto, Masashi| Kagawa, Shunsuke| Kajioka, Hiroki| Taniguchi, Atsuki| Kuroda, Shinji| Kikuchi, Satoru| Kakiuchi, Yoshihiko| Yagi, Tomohiko| Nogi, Shohei| Teraishi, Fuminori| Shigeyasu, Kunitoshi| Yoshida, Ryuichi| Umeda, Yuzo| Noma, Kazuhiro| Tazawa, Hiroshi| Fujiwara, Toshiyoshi| |
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Keywords | Aspirin Ticagrelor P-selectin Platelet Time-lapse imaging |
Note | © 2023 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jul. 2024.| |
Published Date | 2023-07-28 |
Publication Title | Cancer Letters |
Volume | volume567 |
Publisher | Elsevier BV |
Start Page | 216260 |
ISSN | 0304-3835 |
NCID | AA00598513 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 Elsevier B.V. |
File Version | author |
PubMed ID | 37295551 |
DOI | 10.1016/j.canlet.2023.216260 |
Web of Science KeyUT | 001020524700001 |
Related Url | isVersionOf https://doi.org/10.1016/j.canlet.2023.216260 |
Author | Hasei, Joe| Sasaki, Tsuyoshi| Tazawa, Hiroshi| Osaki, Shuhei| Yamakawa, Yasuaki| Kunisada, Toshiyuki| Yoshida, Aki| Hashimoto, Yuuri| Onishi, Teppei| Uno, Futoshi| Kagawa, Shunsuke| Urata, Yasuo| Ozaki, Toshifumi| Fujiwara, Toshiyoshi| |
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Published Date | 2013-03 |
Publication Title | Molecular Cancer Therapeutics |
Volume | volume12 |
Issue | issue3 |
Content Type | Journal Article |
FullText URL | fulltext.pdf |
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Author | Oda, Naohiro| Tabata, Masahiro| Uno, Masatoshi| Umeda, Yuzo| Kato, Hironari| Kubo, Toshio| Senoo, Satoru| Yagi, Takahito| Fujiwara, Toshiyoshi| Maeda, Yoshinobu| Kiura, Katsuyuki| |
Keywords | pancreas mucinous cystadenocarcinoma carboplatin paclitaxel |
Published Date | 2021-09-15 |
Publication Title | Internal Medicine |
Volume | volume60 |
Issue | issue18 |
Publisher | The Japanese Society of Internal Medicine |
Start Page | 2967 |
End Page | 2971 |
ISSN | 0918-2918 |
NCID | AA10827774 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 The Japanese Society of Internal Medicine |
File Version | publisher |
PubMed ID | 33814494 |
DOI | 10.2169/internalmedicine.6730-20 |
Web of Science KeyUT | 000697279400013 |
Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.6730-20 |
JaLCDOI | 10.18926/AMO/62394 |
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FullText URL | 75_4_431.pdf |
Author | Kunitomi, Toshiki| Nasu, Junichirou| Minami, Daisuke| Iwamoto, Takayuki| Nishie, Hiroyuki| Saito, Shinya| Fujiwara, Toshiyoshi| Matsuoka, Junji| |
Abstract | This study aimed to evaluate whether there are differences in the attitudes and practices of cancer pain manage-ment between medical oncologists and palliative care physicians. An online nationwide survey was used to collect responses from board-certified medical oncologists and palliative care physicians in Japan. The survey questionnaire comprised 30 questions. The differences in responses between medical oncologists and palliative care physicians were examined. Out of the 1,227 questionnaires sent, 522 (42.5%) were returned. After apply-ing the exclusion criteria, 445 questionnaires (medical oncologists: n = 283; palliative care physicians: n = 162) were retained for analysis. Among the questions about potential barriers to optimal cancer pain man-agement, both medical oncologists and palliative care physicians considered the reluctance of patients to take opioids due to fear of adverse effects as the greatest barrier. Significantly different ratings between medical oncologists and palliative care physicians were observed on 5 of the 8 questions in this area. Significantly differ-ent ratings were observed for all questions concerning pain specialists and their knowledge. For effective cancer pain management, it is important to account for differences in attitudes and practice between medical oncolo-gists and palliative care physicians. |
Keywords | cancer pain management opioid medical oncologist palliative care physician barriers |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2021-08 |
Volume | volume75 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 431 |
End Page | 437 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 34511609 |
Web of Science KeyUT | 000697944600004 |
NAID | 120007146037 |
FullText URL | fulltext.pdf |
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Author | Matsubara, Takehiro| Soh, Junichi| Morita, Mizuki| Uwabo, Takahiro| Tomida, Shuta| Fujiwara, Toshiyoshi| Kanazawa, Susumu| Toyooka, Shinichi| Hirasawa, Akira| |
Published Date | 2020-02-27 |
Publication Title | BioMed Research International |
Volume | volume2020 |
Publisher | Hindawi |
Start Page | 9349132 |
ISSN | 2314-6133 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 Takehiro Matsubara et al. |
File Version | publisher |
PubMed ID | 32185225 |
DOI | 10.1155/2020/9349132 |
Web of Science KeyUT | 000522222100002 |
Related Url | isVersionOf https://doi.org/10.1155/2020/9349132 |
FullText URL | fulltext.pdf |
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Author | Komoto, Satoshi| Noma, Kazuhiro| Kato, Takuya| Kobayashi, Teruki| Nishiwaki, Noriyuki| Narusaka, Toru| Sato, Hiroaki| Katsura, Yuki| Kashima, Hajime| Kikuchi, Satoru| Ohara, Toshiaki| Tazawa, Hiroshi| Fujiwara, Toshiyoshi| |
Keywords | cancer-associated fibroblast chemotherapy radiotherapy esophageal cancer tumor microenvironment |
Published Date | 2023-05-30 |
Publication Title | Cancers |
Volume | volume15 |
Issue | issue11 |
Publisher | MDPI |
Start Page | 2971 |
ISSN | 2072-6694 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 by the authors. |
File Version | publisher |
PubMed ID | 37296933 |
DOI | 10.3390/cancers15112971 |
Web of Science KeyUT | 001006082400001 |
Related Url | isVersionOf https://doi.org/10.3390/cancers15112971 |