JaLCDOI | 10.18926/40252 |
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Title Alternative | Studies on Paper-analysis in the Field of Balneology. (II) 1. A New Method for the Determination of Cobalt in Blood. 2. Effects of Radioactive Thermal Bathing and Internal Use of Vitriol Water upon Cobalt Levels in Blood. |
FullText URL | 024_029_053.pdf |
Author | Ishibashi, Maruo| |
Abstract | 1. A new method for the determination of cobalt in blood. The author proposed a new method for the determination of cobalt in blood by means of paper-chromatography. The procedure is follows. In a Kjeldahl colben, 5 m!. of blood is taken, and turned into wet ash with 3 ml. of HNO(3), 0.5 ml. of H(2)SO(4) and 1.5 ml. of HClO(4) and the ash aqueus solution is then neutralized with ammonium hydroxid, the neutralization being indicated by the development of color of 0.1% of p-nitrophenol (one drop) added to the solution. After addition of 2 ml. of 40% ammonium citrate, 0.5 ml. of 20% Na(2)S(2)O(3), 3~5 drops of H(2)O(2) and 1 ml. of o-nitrosoresorcine monomethyl ether (hereafter N.R.M.E.), the mixture is left for at least 15 minutes and the aqueus solution is taken in a stoppered test tube (inside diameter: 1.3 cm., hight: 16.5 cm.). The mixture is shaken with 2 ml. of carbon tetrachloride. Carbon tetrachloride is shaken with 5 ml. of 20% Na(2)CO(3) solution. Then the excess of N.R.M.E. is removed and carbon tetrachloride is concentrated on water bath to 0.3~0.5 ml. and all CCl(4) is used for a determination sample. The sample is placed on the paper (Toyo-filter paper No. 50 or 51A) in a thin line at a distance of 3 cm. from the edge, and the spot is developed with a mixture of 20 ml. of CCl(4) and 1 ml. of 90% ethylalcohoI. After development for 30~40 min., an orange-colored linear spot appears at a distance of 9~10 em. from the origin point. Spot intensity is measured at 460 mμ with Natsume's densitometer and quantitative estimation is made comparing with the standard graph. 2. Effects of radioactive thermal spring bathing and internal use of vitriol water upon cobalt levels in blood. As the author's method above-mentioned is able to determine the cobalt level in a small amount of blood, it is very convenient in investigating cobalt metabolism in the field of balneology. The author examined the changes of cobalt levels in blood after radioactive thermal bathing as well as after internal use of acid vitriol water. a. By the author's method cobalt in normal human blood was 0.4~3.6γ/100ml. in man (average: 1.6±0.4γ/100ml.) and 0.2~2.2γ/100ml. in woman (average: 0.7±0.3γ/100ml.). b. The cobalt levels in blood were measured by the author's method before and 5, 30, 60 minutes after the radioactive thermal single bathing, and before and 1, 2, 3, 4 weeks after a series of radioactive thermal baths (Rn-content: 10~30 Mache, 42~3°C., for 10 minutes). The cobalt levels in the blood of healthy subjects showed no significant change after the thermal single bathing, but those of patients with rheumatoid arthritis showed a slight increase on 3rd or 7th day and a fall on 2nd week of a series of radioactive thermal baths and then tended to return to the initial levels during the 3rd and 4th weeks of spa treatment. c. Thirty ml. of Yanahara mineral water (an acid vitriol water, pH: 2.2) was diluted with plain water to 200 ml. (Co(++)content: ca.3γ) and administered to healthy fasting subjects orally. Blood samples were taken from the cubital vein before and 1, 3, 6 hours after the intake of the vitriol water. The cobalt levels in the blood showed an increase of 14% of the initial levels at 1 and 3 hours and a decrease of 22% at 6 hours after the drinking of Yanahara mineral water. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1959-01 |
Volume | volume24 |
Start Page | 29 |
End Page | 53 |
ISSN | 0369-7142 |
Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/40250 |
language | Japanese |
File Version | publisher |
NAID | 40017532366 |
JaLCDOI | 10.18926/40265 |
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Title Alternative | Studies on Paper-Analysis in the Field of Balneology (I) Studies on Iron in Serum by Means of Parper-Electrophoresis and Paper-Chromatography |
FullText URL | 022_037_054.pdf |
Author | Ishibashi, Maruo| |
Abstract | 1. The author showed by means of paper-electrophoresis using o-nitrosoresorcinmonomethylether (hereafter N. R. M. E.), a colourdeveloping reagent, that iron in serum combines with β-fraction of serum protein. 2. The author proposed a new method for the determination of serum iron by means of paper-chromatography. Procedure is as follows. In a centriguged tube, 0.5 ml. of clear serum is taken, acidified with 0.15 ml. of 20% HNO(3), and allowed to stand for 20 minutes. After addition of 0.2 ml. of saturated solution of CH(3)COONa and 1 ml. of acetic acid-sodium acetate buffer solution (pH: 3.8), the mixture is kept for at least 10 min. and filtered through Toyo-filter-paper No.5 A. The clear filtrate is taken in a stoppered test tube (the inside diameter: 1.2 cm.; height: 15 cm.). To this filtrate are added 0.2 ml. of 20% Hydroxylamine hydrochloride and 0.25 ml. of saturated aqueous solution of N. R. M. E. After being allowed to stand for at least 20 min., the mixture is shaken with 5 ml. of carbon tebrachloride. Then the excess of N. R. M. E. is removed. The supernatant aqueous solution (0.2 ml.) is used for a determination sample. The sample is placed on the paper (Toyo,filter-paper No.51 or 50) in a thin line at a distance of 10 cm. from the edge, and the spots are developed with 90 % ethylalcohol. After development for 4-6 hours, a green-coloured linear spot appsars at a distance of 12-16 cm. from the origin-point. Spot intensity at 670 mμ is measured with Natsume's densitometer, and from this, concentration of Fe can be estimat.ed on the standard graph (Fig. 5). 3, Effects of radioactive thermal spring bathing and internal use of vitriol water upon serum iron levels were studied with the result.s as follows. The above-mentioned author's method of determining the iron level in a small amount of serum is very convenient in investigating iron metabolism in the field of balneotherapy. The author examined changes of iron levels in serum after radioactive thermal bathing as well as after internal use of acid vitriol water. a) The iron levels in serum were maasurecl by the author's method before and 5, 30 and 60 minutes after the radioactive thermal bath (Rn-content: 10-30 Mache, 42-3°C., for 10 min,). The iron levels in the serum of healthy subjects showed no significant change after the thermal bathing. b) Yanahara Mineral Water (an acid vitriol water, pH; 2.2) contains 0.045 gm. of Cl(-), 12.35 gm. of SO(4)(--), 2.5 gm. of Fe(++)+Fe(+++), 0.0938 gm. of Al(+++) and 0.0001 gm. of Cobalt in one liter. i) Thirty ml. of Yanahara, water diluted with plain water to 200 ml. (Fe(++) content: ca. 75 mg.) and administered to health fasting subjects orally. As a control matter, 0.65 gm. of Glukon-F powder (Fe(++) content.: ca. 75 mg.) was then given. Blood samples were taken from the cubital vein before and 1, 3 and 6 hours after the intake of the dtriol water. Iron contents of the serum samples were measured by the author's paper chromatographic method. The results were shown in the table and the figure. The iron contents of the serum after the intake of the mineral water were higher than in the case of the control. ii) Two ml. of Yanahara vitriol water was administered to rabbits with the aid of a stomach tube, and serum iron levels wera determined before and 1, 3, 4 and 6 hours after the administration. An amount of 0.05 gm. of Glukon-F powder was dissolved in 5 ml. of plain water, and this solution was given to rabbits as a control. After the internal use of vitriol water, iron levels in serum rose and remained unexpactedly high for about 1-4 hours, in a manner that did not. correspond to the amount of iron in the given mineral water. So that it was suspected that the iron originally contained in the living subjects had been mobilized by the intake of vitriol water. Iron levels in serum after administration of a solution of Glukon-F powder were lower than in the case of the mineral water. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1958-07 |
Volume | volume22 |
Start Page | 37 |
End Page | 54 |
ISSN | 0369-7142 |
Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/40263 |
language | Japanese |
File Version | publisher |
NAID | 40017532359 |
JaLCDOI | 10.18926/40402 |
---|---|
Title Alternative | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (VII) POSSIBILITY OF CHEMICAL PROSPECTING OF MINERAL SPRINGS |
FullText URL | pitsr_010_001_002.pdf |
Author | Umemoto, Shuji| |
Abstract | The results of the previous reports I-VI were synthetically discussed, and the possibility of the chemical prospecting of mineral springs was concluded. That is, by determining the chloride and sulfate content and water temperature of well waters and the amounts of chloride and sulfate fixed to the soil, the existence of mineral springs will be prospected. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-03 |
Volume | volume10 |
Start Page | 1 |
End Page | 2 |
ISSN | 0369-7142 |
Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/40400 |
language | Japanese |
File Version | publisher |
NAID | 120002509291 |
JaLCDOI | 10.18926/40376 |
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Title Alternative | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (II) SEKIGANE HOT-SPRINGS, TOTTORI PREFECTURE, JAPAN |
FullText URL | 009_006_009.pdf |
Author | Umemoto, Shunji| |
Abstract | In Sekigane Hot-Springs, the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from the various parts of the thermal spring district and its neighbourhood. The chloride and sulfate content of the well water samples collected from the thermal spring district were higher than those from its neighbourhood, and no difference was found for the water temperatures. The amonnts of chloride fixed to the soil in the samples collected from the thermal spring district were greater than those from its neighbourhood, and the amounts of sulfate in the samples collected from the thermal spring district were extremely greater than those from its neighhourhood. As the existence of other sources which would supply the chloride and sulfate to the water and soil is not expected, the difference in the chloride and sulfate content and water temperatures, between the sa.mples from the thermal spring district and its neighbourhood, seems to be due to the effects of thermal springs. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-01 |
Volume | volume9 |
Start Page | 6 |
End Page | 9 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 40017532512 |
JaLCDOI | 10.18926/40380 |
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Title Alternative | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (VI) DISTRICT NEAR THE SPRING IN KITADANI VILLAGE, TOTTORI PREFECTURE, JAPAN |
FullText URL | 009_024_027.pdf |
Author | Umemoto, Shunji| |
Abstract | In Fukudome, Kitadani Village, the chloride, sulfate and phosfate content and water temperatures of well waters and the amounts of chloride and sulhte fixed to the soil were determined with the samples collected from various parts near the spring which contains much inorganic salts. The chloride, sulfate and phosfate content of the well water samples collected from the district which surrounds the spring, were higher than those from its neighhonrhood, but for the water temperatures of the well water samples, no difference was recognized. As the existence of other sources which would supply the chloride, sulthte and phosfate to the well water is not expected, the difference in the chloride, sulfate and phosfate content of well waters between the samples collected from the A district and its neighbourhood, seems to be due to the effects of the spring which contains much inorganic salts or its sources. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-01 |
Volume | volume9 |
Start Page | 24 |
End Page | 27 |
ISSN | 0369-7142 |
Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/40388 |
language | Japanese |
File Version | publisher |
NAID | 40017532512 |
JaLCDOI | 10.18926/40378 |
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Title Alternative | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (IV) TAMATSUKURI HOT-SPRINGS, SHIMANE PREFECTURE, JAPAN |
FullText URL | 009_016_019.pdf |
Author | Umemoto, Shunji| |
Abstract | In Tamatsukuri Hot-Springs, the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from various parts of the mineral spring districts. For the values which were determined with samples collected from the thermal spring districts and its neighbourhood, no difference was recognized. This result is quite different from the results given in the previous reports of the present author. But this fact may be explaned as the effects of the sea warter, and the further study is being continued. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-01 |
Volume | volume9 |
Start Page | 16 |
End Page | 19 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 40017532512 |
JaLCDOI | 10.18926/40379 |
---|---|
Title Alternative | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (V) HAMAMURA AND KACHIMI HOT-SPRINGS, TOTTORI PREFECTURE, JAPAN |
FullText URL | 009_020_023.pdf |
Author | Umemoto, Shunji| |
Abstract | In Hamamura and Kachimi Hot-Springs, the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from vmions parts of the mineral spring districts. The chloride and sulfate content and warter temperatures of well waters were higher in the samples collected from the thermal spring districts than in the samples collected from its neighbourhood, but for the amounts of chloride and sulfate fixed to the soil, no difference was recognized. As the existence of other sources whlch would supply the chloride, sulfate and heat to the well waters is not expected, the difference in the chloride and sulfate content and water temperatures of well waters, between the samples collected from the thermal spring districts and its neighbourhood, seems to he due to the effects of the thermal springs. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-01 |
Volume | volume9 |
Start Page | 20 |
End Page | 23 |
ISSN | 0369-7142 |
Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/40388 |
language | Japanese |
File Version | publisher |
NAID | 40017532512 |
JaLCDOI | 10.18926/40377 |
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Title Alternative | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (III) SIIGAKU AND YUGAKAI HOT-SPRINGS, SHIMANE PREFECTURE, JAPAN |
FullText URL | 009_010_015.pdf |
Author | Umemoto, Shunji| |
Abstract | 1) In Shigaku Hot-Springs, the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from various parts of the thermal spring district and its neighbourhood. The amounts of chloride and sulfate fixed to the soil were greater in the samples from the thermal spring district than in those from its neighbourhood. As the existence of other sources which would supply the chloride and foulfate to the soil is not expected, the difference in the amounts of chloride and sulfate, between the samples from the thermal spring district and it; neighbourhood, seems to be due to the effects. of thermal springs. 2) In Yugakai Hot-Springs the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from various parts of the mineral spring district. The water temperatures of well water samples from the district which has the mineral springs with higher temperatures, were higher than those from the district which has the mineral springs with lower temperatures, but for the chloride and sulfate content of the well water samples and the amounts of chloride and sulfate fixed to the soil, no difference was detected. As the existence of other sources which would supply the heat to the water is not expected, the difference in the water temperatures, between the samples from the district which has the mineral springs with higher temperatures and the district which has the mineral springs with lower temperatures, seems to be due to the effects of the mineral springs. On the other hand, for the chloride and sulfate content of well water samples and the amounts of chloride and sulfate fixed to the soil, no difference is recognized. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-01 |
Volume | volume9 |
Start Page | 10 |
End Page | 15 |
ISSN | 0369-7142 |
Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/40388 |
language | Japanese |
File Version | publisher |
NAID | 40017532512 |
JaLCDOI | 10.18926/40352 |
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Title Alternative | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE A;\lD SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (VIII) MATSUZAKI, TOGO AND ASOZU HOT SPRINGS, TOTTORI PREFECTURE, JAPAN |
FullText URL | 012_001_005.pdf |
Author | Kimura, Kenjiro| Umemoto, Shunji| |
Abstract | In Matsuzaki, Togo and Asozu Hot Springs which issue around the Pond Togo, the chloride and sulfate content and water temperatures of well waters and the amount of chloride and sufate fixed to the soil were determined with samples collected from various parts of the thermal spring districts and its neighborhood. The chloride and sulfate content and water temperatures of the well water samples collected from the thermal spring districts were higher than those from its neighbourhood, but for the amounts of chloride and sulfate fixed to the soil, no difference was detected. As the existence of other sources which would supply the chloride, sulfate and heat to the water is not expected, the difference in the chloride and sulfate content and water temperatures of well waters, between the samples collected from the thermal spring districts and its neighbourhood, seems to be due to the effects of thermal springs. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-09 |
Volume | volume12 |
Start Page | 1 |
End Page | 5 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 40017532436 |
JaLCDOI | 10.18926/40375 |
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Title Alternative | STUDIES ON THE CHLORIDE AND SULFATE CONTENT OF WELL WATERS AND THE AMOUNTS OF CHLORIDE AND SULFATE FIXED TO THE SOIL IN THE MINERAL SPRING DISTRICTS (I) MISASA HOT-SPRINGS, TOTTORI PREFECTURE, JAPAN |
FullText URL | 009_001_005.pdf |
Author | Umemoto, Shunji| |
Abstract | In Misasa Hot-Springs, the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from various parts of the thermal spring district and its neighbourhood. The chloride and sulfate content and water temperatures of the well water samples collected from the thermal spring district were higher than those from its neibourhood, and the amounts of chloride fixed to the soil were greater in the samples collected from the thermal spring district than in those from its neighbourhood, but for the amounts of sulfate fixed to the soil, no difference was detected. As the existence of other sources which would supply the chloride and sulfate to the water and soil is not expected, the difference in the chloride and sulfate content and water temperatures, between the samples collected from the thermal spring district and its neighbourhood, seemes to be due to the effects of thermal springs. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-01 |
Volume | volume9 |
Start Page | 1 |
End Page | 5 |
ISSN | 0369-7142 |
Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/40388 |
language | Japanese |
File Version | publisher |
NAID | 40017532512 |
JaLCDOI | 10.18926/40426 |
---|---|
Title Alternative | CHEMICAL STUDIES ON THERMAL ALGAE (I) ON INORGANIC CONSTUENTS (1) |
FullText URL | pitsr_012_011_014.pdf |
Author | Umemoto, Shunji| Mifune, Masaaki| |
Abstract | The thermal algae which grew in the thermal water of Misasa Hot Springs, namely Mastigocladus laminosus Cohn (1), Phormidium ambiguum Gomont (2), Oscillatoria Cortiana (Menegh.) Gomont (3) and the fresh water alga which grew in the River Misasa, namely Rhizocolonium hieroglyphicum (4) were collected. The spectrographic analysis and quantitative chemical analanalysis of the ashes of the algae gave the following results : 1. All four algae contained Cu, Zn, Al, Pb, Mn, Mo besides the phisiological elements. 2. Two algae, (1) and (2) which grew in thermal water rarely mixed with the river water, contained Ti and considerable amount of Ge. 3. The highest content of Si and highest value of ash per cent were those of (1), and their values were 27.22 % and 26.44 %. 4. The highest content of Fe and Mn were those of (2), and their values were 17.80 % and 3.27 %. 5. Great difference was not detected between the ratios of MgO/CaO of (1) and (2), and their values were 0.13 (1) and 0.14 (2). |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-09 |
Volume | volume12 |
Start Page | 11 |
End Page | 14 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 120002509303 |
JaLCDOI | 10.18926/40427 |
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Title Alternative | INDICE DE NUTRITION AND OXIDATIOM-REDUCTION POTENIAL OF MINERAL WATERS |
FullText URL | pitsr_012_015_020.pdf |
Author | Oshima, Yoshio| |
Abstract | Indice de nutrition (Pech), indice de nutrition simplifié (Rimattei), membrane potential difference of human skin, and oxidation-reduction potential of several mineral watem were measured. Their balneological significance was discussed. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-09 |
Volume | volume12 |
Start Page | 15 |
End Page | 20 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 120002509304 |
JaLCDOI | 10.18926/15535 |
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Title Alternative | FLOCCULATION VALUE OF MINERAL WATERS. |
FullText URL | 005_082_083.pdf |
Author | Ashizawa, Takashi| |
Abstract | Flocculation value of 24 mineral waters was measured with colloidal solution of iron hydroxide. There exists a negative correlation (r=-0.72, Fo=(r(2)(N-2))/(1-r(2)) =21.6 >F=8.10 n1=1 n2=20 α=0.01) between the logarithms of sulfate ion concentration of the mineral waters and their Flocculation value. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1951-08 |
Volume | volume5 |
Start Page | 82 |
End Page | 83 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 120002307827 |
JaLCDOI | 10.18926/21179 |
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Title Alternative | Studies on sinter deposit Misasa radioactive hot springs |
FullText URL | pitsr_048_025_033.pdf |
Author | Furuno, Katsushi| Tetsumoto, Junko| Aoki, Hiroko| Mifune, Masaaki| Morinaga, Hiroshi| Fukushima, Satoru| Wada, Hiroaki| |
Abstract | Sinter deposit in a distributing pipe used for about fifteen years in Misasa radioactive hot springs was investigated. The results were as follows; 1. The metal elements in this deposit were quaIi. tatively analysed by spectraspan plasma emission spectrophotometry (SPES), by fluorescent X-ray spectrometry, and following elements were detected; B, Na, Mg, AI, K, Ca, Mn, Fe, Cu, Zn, As, Sr, Ba and Pb. 2. The metal elements in this deposit were quantatively analysed by SPES and atomic absorption spectrophotometry, and following elements were determined; Fe : 508.7, As: 26.40, Ca: 7.85, Mn : 2.00, Al : 1.80, Na: 1.60, Zn: 1.33, K: 0.80, Cu: 0.67, Sr: 0.47, Mg: 0.35, Ba: 0.33 and B : 0.30 mg per gram. The color of this deposit was red brown, and the main component was ferric oxide. 3. Radioactive elements in this deposit were detected by autoradiography and radioluxography. Among the radioactive elements, concentration of radium was 320.5×10(-12)g/g (313.0×10(-12)Ci/g). |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1979-03-25 |
Volume | volume48 |
Start Page | 25 |
End Page | 33 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 120002310949 |
JaLCDOI | 10.18926/21138 |
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Title Alternative | The Effect of Thermal Spring Water on Drug Absorption in Special Reference to Aspirin and Indomethacin |
FullText URL | pitsr_052_045_050.pdf |
Author | Okamoto, Teruko| Hirano, Mitsuhiro| Furuno, Katsushi| |
Abstract | It is thought that a drug reacts differently with media taken internally. The solubility of Aspirin is assured 600μg/ml in 30min. with Misasa spring water, whereas 400μg/ml with plain water. The parallel difference of 200μg/ml follows 10 min. thereafter. Maximum serum concentratin of 200μg/ml is obtained 2 hours after the internal use of Aspirin with Misasa spring water in parallel difference of 20μg/ml with plain water. In the case of Indomethacin intake, maximum serum concentration of 1.5μg/ml is obtained in 2 hours with plain water, whereas maximum serum concentration of 1μg/ml is obtained in the same period with Misasa spring water. However, the difference of 0.25μg/ml in serum concentration between the media internally taken is seen initially and after 4 hours under high concentration of Indomethacin. We, therefore, assume tentatively that the effect of Aspirin and Indomethacin is supposed to be enhanced with Misasa spring water taken internally. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1982-03-25 |
Volume | volume52 |
Start Page | 45 |
End Page | 50 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 120002311035 |
JaLCDOI | 10.18926/40179 |
---|---|
Title Alternative | Study on effects of balneotherapy on blood pH, P(CO(2)) and P(O(2)) Part 3. The effects of balneotherapeutical procedures on blood pH, P(CO(2)) and P(O(2)) |
FullText URL | 038_027_044.pdf |
Author | Yahata, Takaaki| |
Abstract | The effects of balneological procedures as well as the duration of hospitalization on blood pH, P(CO(2)) and P(O(2)) were studied in fifty-two patients chiefly including rheumatoid arthritics. The changes of these parameters in sixty minutes after any foment were discussed comparing with those in the control groups. The results were as follows. 1) Blood pH decreased in value from first to second hospital week and thereafter remained almost constant. No P(CO(2)) variation was observed. The P(O(2)) remained stable till third hospital week and then followed by up and down changes during the forth to the ninth week. 2) The arterial blood pH, P(CO(2)) and P(O(2)) in all showed a tendency to increase after the general spring bath of ten minutes duration (bath temp. : 40±1℃). The venous blood pH and P(O(2)) also increased as in the arterial but P(CO(2)) decreased. These non significcant changes in the venous blood were considered to be resulted from the increased cutaneous blood flow in the forearm. 3) It was showed that mud bath of twenty minutes duration (bath temp. : 40±1℃) made an influence on the venous blood pH, P(CO(2)) and P(O(2)) via two different mechanisms. The first is the increased blood flow which had five minute value of P(O(2)) and pH elevated but P(CO(2)) reduced significantly. The second is the prominent increase of oxygen uptake in which the significant reduction of five minute P(O(2)) value but no variation of pH or P(CO(2)) was demonstrated. It was suggested that these two types of variations were based on the difference of individual response to heat. 4) The signiilcant blood pH, P(CO(2)) and P(O(2)) changes after mud pack of twenty minutes duration (surface temp. : 40~50℃) were considered to reflect the increased blood flow. 5) The increased cutaneous blood flow induced by balneotherapeutical procedures was proved to remain as long as sixty minutes thereafter in almost all cases. 6) The blood pH, P(CO(2)) and P(O(2)) changes observed in the control groups were related mainly with the increased blood flow and only little, if any, with the elevated oxygen uptake. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1969-03-20 |
Volume | volume38 |
Start Page | 27 |
End Page | 44 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 40017532344 |
JaLCDOI | 10.18926/40178 |
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Title Alternative | Study on effects of balneotherapy on blood pH, P(CO(2)) and P(O(2)) Part 2. Relationships between the physiopathological factors and blood pH, P(CO(2)) and P(O(2)) |
FullText URL | 038_011_025.pdf |
Author | Yahata, Takaaki| |
Abstract | From the factors which are considered to make an effect on circulatory or metabolic states, hemoglobin content, erythrocyte sedimentation rate, room temperature, respiratory rate and pulse rate were chosen to be discussed their relationships between the pH, P(CO(2)) and P(O(2)). Moreover, changes due to age and disease as well as diurnal and seasonal variations of blood pH, P(CO(2) and P(O(2)) were evaluated. 1) Blood pH and Peo2 showed the tendency of reduction in the order of 40~59, 10~39 and 60~79 years age group in the former and in the latter 40~59, 60~79 and 10~39 years age group. The P(O(2)) value in the afternoon decreased with ageing. However, no significance was demonstrated in any age group. 2) Diurnal changes of pH in 10~59 age group was very small. In the 60~79 age group, the afternoon value decreased than the morning one. The P(O(2)) value in the 10~59 age group increased in the afternoon contrasted to the decreasement in the 60~79 age group. The P(CO(2)) variations in all age groups were within the errors due to the measurement. 3) Rheumatiod arthritics group showed no significant diurnal variation different from non-rheumatoid arthritics group. 4) Blood pH of December-February group showed the lowest seasonal value and significant difference between March - May and September - November group. No significant seasonal variation was observed in the blood P(CO(2)) and P(O(2)). 5) The central nervous system group showed the significant lower blood pH than cardiovascular disease and rheumatoid arthritis group. The P(CO(2)) values of rheumatoid arthritis group were lower significantly than cardiovascular disease, central nervous system, and musculo- keletal system patient groups. None of diseases showed significant P02 difference each other. 6) Significant relationship was demonstrated between erythrocyte sedimentation rate and P(O(2)) value only in cardiovascular disease patient group. 7) There were the significant relationships between room temperature and P(O(2)) in rheumatoid arthritis and metabolic disease groups. 8) Significant relationships were shown between respiratory rate and pH in rheumatoid arthritis and cardiovascular disease groups. 9) There was significant relationship between pulse rate and pH only in rheumatoid arthritis groups. 10) The combination of the blood pH, P(CO(2)) and P(O(2)), values was shown to reflect the circuratory or metabolic states of the tissues or organs and to remain stable on the experimental day. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1969-03-20 |
Volume | volume38 |
Start Page | 11 |
End Page | 25 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 40017532343 |
JaLCDOI | 10.18926/40177 |
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Title Alternative | Study on effects of balneotherapy on blood pH, P(CO(2)) and P(O(2)) Part I. Evaluation of measurement apparatus and methods of the proccedures |
FullText URL | pitsr_038_001_009.pdf |
Author | Yahata, Takaaki| |
Abstract | Human venous blood pH, P(CO(2)) and P(O(2)) were measured with I. L. Meter. Its reproducibility and response rate were evaluated as well as methods of the procedures. 1) Time required to reach the stability of pH, P(CO(2)), and P(O(2)) reading after the sampie injection was 1~1.5 min., 2~2.5 min. and 45~75 sec., respectively. It is recommended in the measurement of these parameters at the same time that the sample injection starts with P(CO(2)) electrode, followed by pH and P(O(2)) in this order and that readings are recorded in the order of pH, P(O(2)) and P(CO(2)). 2) Range of differences between the two values measured in the interval of 3~5 min. were pH : -0.010~0.020 (mean: 0.003), P(CO(2)) : -1.0~1.0mmHg (mean: 0.4) and P(O(2)) : -1.0~0.0mmHg (mean: -0.5). Their 5% rejection limits were 0.021≧x(o)≧-0.015, 2.0≧x(o)≧-1.2mmHg and 0.3≧x(o)≧-1.3mmHg, respectively. 3) The pH, P(CO(2)) and P(O(2)) of the heparinized venous blood stored in ice water showed no significant changes in 60 min. and they gave practically the same results as the measurement just after shedding. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1969-03-20 |
Volume | volume38 |
Start Page | 1 |
End Page | 9 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 120002398499 |
JaLCDOI | 10.18926/15584 |
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Title Alternative | SENSITIVITY TO HISTAMINE DURING A SERIES OF THERMAL BATHS. |
FullText URL | 006_049_051.pdf |
Author | Oshima, Yoshio| Yokota, Takeo| |
Abstract | Sensitivity of mice to histamine was estimated with the death-rate by its subcutaneous injection. In control group without bath ten mg. of histamine per ten g. of body weight proved to be tolerable, but twenty mg. of histamine per ten g. of body weight was lethal in August. To 24 mice were given everyday a plain water bath at 37℃ for ten minutes. To another 24 mice were given everyday a thermal bath of Misasa at 37℃for ten minutes. On the 4th, 7th, 14th and 21st day to each six mice of both groups was given a subcutaneous injection of histamine, namely to three mice was given ten mg. of histamine per ten g. of bodyweight and to another three mice was given twenty mg. of histamine per ten g. of body weight. In plain water bath group no change in death rate was shown during the series of bath days. But in the thermal bath group a 100% 1ethality was recognized on the 4th day, 67% lethality was proved on the 7th day and only 17% lethality was shown on the 14th day. Histamine or histaminelike substance is known to be a chemical agent liberated in the skin by any skin irritants. And the above-mentioned change in the sensitivity to histamine during a series of thermal baths suggests an explanation to the mechanism of thermal crisis that has a tendency to occur in the first week of thermal bath cure. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1952-03 |
Volume | volume6 |
Start Page | 49 |
End Page | 51 |
ISSN | 0369-7142 |
language | Japanese |
File Version | publisher |
NAID | 120002307862 |
JaLCDOI | 10.18926/40430 |
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Title Alternative | PROTECTIVE EFFECT OF THERMAL BATHS AGAINST TOTAL BODY X-IRRADIATION CHANGES OF LIVER-CATALASE ACTIVITY IN MICE |
FullText URL | pitsr_012_030_033.pdf |
Author | Okada, Toshio| |
Abstract | The author investigated the effect of a series of thermal baths of Misasa, (at 37°C for 10 minutes), upon the liver-catalase activity in X-irradiated mice. The thermal baths, following LD 50 dose of X-irradiation (450r) or following a successive X-irradiation of daily 50r for 6 - 25 days decreased the liver-catalase activity more marked than control without baths. On the other hand, thermal baths prior to X-irradiation prevented the fall of liver-catalase activity in the X-irradated mice. |
Publication Title | 岡山大学温泉研究所報告 |
Published Date | 1953-09 |
Volume | volume12 |
Start Page | 30 |
End Page | 33 |
ISSN | 0369-7142 |
Related Url | http://ousar.lib.okayama-u.ac.jp/40422 |
language | Japanese |
File Version | publisher |
NAID | 120002509306 |