result 13393 件
| Author | 岡山大学温泉研究所| |
|---|---|
| Published Date | 1971-03-26 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume40 |
| Content Type | Others |
| Author | 岡山大学温泉研究所| |
|---|---|
| Published Date | 1972-03-25 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume41 |
| Content Type | Others |
| Author | 岡山大学温泉研究所| |
|---|---|
| Published Date | 1973-03-25 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume42 |
| Content Type | Others |
| JaLCDOI | 10.18926/AMO/40135 |
|---|---|
| FullText URL | 64_4_263.pdf |
| Author | Pavelić, Jasminka| Čulić, Srdjana| Čulić, Vida| |
| Abstract | The occurrence of Langerhans cell histiocytosis (LCH) and another malignancy in the same patient is infrequent but has been recognized. The genetic changes that could be responsible for LCH and/or concomitant leukemia development are obscure. To the best of our knowledge, this is the first description of constitutional maternally derived inv (9) (p12;q13) in an LCH patient, and also of the development of common ALL Ph after LCH diagnosis and therapy. The potential significance of these findings [inv (9)LCHALL Ph] and their mutual relationship are unknown. Therefore, cooperative studies of large numbers of patients are needed to identify the common risk factors, if any. |
| Keywords | acute lymphoblastic leukemia genetic changes langerhans cell histiocytosis |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-08 |
| Volume | volume64 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 263 |
| End Page | 265 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20802544 |
| Web of Science KeyUT | 000281384400008 |
| JaLCDOI | 10.18926/AMO/40134 |
|---|---|
| FullText URL | 64_4_257.pdf |
| Author | Moritani, Norifumi| Yamada, Tomohiro| Mizobuchi, Koichi| Wakimoto, Mari| Ikeya, Yoko| Matsumura, Tatsushi| Mishima, Katsuaki| Iida, Seiji| |
| Abstract | The term atypical lipomatous tumor (ALT) is synonymous with well-differentiated liposarcoma (WDL). This tumor occurs very rarely in the tongue. Thus, it is difficult to predict its prognosis. Although recurrence of ALT/WDL is thought to be unlikely after complete excision, long-term follow-up is necessary when considering the pathologic conditions of this tumor at other sites. Here, we report a case of an ALT of the tongue, with a review of the literature. A 68-year-old man was referred to our hospital because of a tumor on the left side of his tongue. Upon palpation, the tumor was 12mm in diameter, circumscribed, elastic and hard, well demarcated, movable, and painless. We diagnosed the lesion as a lipoma and extirpated the tumor under local anesthesia. Because the specimen was histopathologically diagnosed as an ALT, as a precaution, we excised an additional 5mm from the area surrounding the original tumor under general anesthesia. Three years after the operation, the tongue demonstrated good healing without paresthesia or dysfunction, and to date there has been no evidence of recurrence. |
| Keywords | atypical lipomatous tumor well-differentiated liposarcoma tongue |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-08 |
| Volume | volume64 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 257 |
| End Page | 261 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20802543 |
| Web of Science KeyUT | 000281384400007 |
| JaLCDOI | 10.18926/AMO/40133 |
|---|---|
| FullText URL | 64_4_249.pdf |
| Author | Masumoto, Akio| Masuyama, Hisashi| Takamoto, Norio| Akahori, Yoichiro| Hiramatsu, Yuji| |
| Abstract | It has been reported that prolactin (PRL) is cleaved to 14 or 16 kDa fragments by cathepsin D in vitro and in vivo, and that such fragments exhibit antiangiogenic and proapoptotic properties. The aim of this study was to investigate the relationship between pregnancy induced hypertension (PIH) and the placental expression of antiangiogenic PRL fragments and cathepsin D. Placental expression of PRL fragments and cathepsin D was evaluated by Western blot analysis in a group of 9 pregnant women consisting of 5 normal pregnancies and 4 severe PIH cases. Antiangiogenic PRL fragments were detected in 4 placental samples from all PIH cases but not detected in those from normal pregnancies (p0.05). The expression of cathepsin D in PIH placentas was significantly lower than that in those without PIH (p0.05), while the placental expression of procathepsin D was significantly greater in PIH cases than in the normal pregnancies (p0.05). These data suggest that antiangiogenic PRL fragments in the placenta may be present only in PIH cases, and that PRL fragments in the placenta might be implicated in the pathophysiology of PIH. |
| Keywords | pregnancy induced hypertension preeclampsia prolactin prolactin fragment cathepsin-D |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-08 |
| Volume | volume64 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 249 |
| End Page | 255 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20802542 |
| Web of Science KeyUT | 000281384400006 |
| JaLCDOI | 10.18926/AMO/40132 |
|---|---|
| FullText URL | 64_4_243.pdf |
| Author | Myo-Khin| Myat-Tin-Htwe-Kyaw| Yi-Yi-Kyaw| Ohmar-Lwin| Myat-Phone-Kyaw| Khin-May-Oo| Shimono, Kunio| Koide, Norio| Okada, Shigeru| |
| Abstract | The efficacy of AntiOxidant Biofactor (AOB(R)) for the management of apparently healthy subjects with chronic hepatitis C infection was investigated. A total of 60 subjects (35 males, 25 females) participated in the trial. AOB was given orally in 2 packs (3g per pack) 3 times per day. 17 subjects had taken AOB for 3 years, 31 subjects up to 2 years, and 41 subjects up to one year. The initial mean (SD) serum alamine aminotransferase (ALT) level was 46.3+/-35.4IU/L, and significant (p0.05, paired t-test) reductions in the mean serum ALT levels were observed at 6 months (38.6+/-21.5IU/L), 18 months (31.9+/-18.1IU/L), 2 years (31.2+/-14.6IU/L), and 3 years (28.0+/-15.9IU/L). Those presenting with high serum ALT levels (30 subjects) demonstrated significant levels (p0.05, paired t-test) of reduction in the mean serum ALT levels at 6, 12, 18, 24, and 36 months of treatment. No side effects were observed and the AOB treatment was well tolerated by all subjects. |
| Keywords | hepatitis C AntiOxidant Biofactor (AOB®) ALT level |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-08 |
| Volume | volume64 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 243 |
| End Page | 248 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20802541 |
| Web of Science KeyUT | 000281384400005 |
| JaLCDOI | 10.18926/AMO/40131 |
|---|---|
| FullText URL | 64_4_233.pdf |
| Author | Matsuoka, Hiroyuki| Ikezawa, Tsunetaka| Hirai, Makoto| |
| Abstract | We are producing a transgenic mosquito, a flying syringe, to deliver a vaccine protein to human beings via the saliva the mosquito deposits in the skin while biting. The mosquito produces a vaccine protein in the salivary gland (SG) and deposits the protein into the host's skin when it takes the host's blood. We chose circumsporozoite protein (CSP), currently the most promising malaria vaccine candidate, to be expressed in the SG of Anopheles stephensi. To transform the mosquitoes, plasmid containing the CSP gene under the promoter of female SG-specific gene, as well as the green fluorescent protein (GFP) gene under the promoter of 3xP3 as a selection marker in the eyes, was injected into more than 400 eggs. As a result, five strains of GFP-expressing mosquitoes were established, and successful CSP expression in the SG was confirmed in one strain. The estimated amount of CSP in the SG of the strain was 40ng per mosquito. We allowed the CSP-expressing mosquitoes to feed on mice to induce the production of anti-CSP antibody. However, the mice did not develop anti-CSP antibody even after transgenic mosquitoes had bitten them several times. We consider that CSP in the SG was not secreted properly into the saliva. Further techniques and trials are required in order to realize vaccine-delivering mosquitoes. |
| Keywords | malaria salivary gland flying syringe transgenic mosquito vaccine |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-08 |
| Volume | volume64 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 233 |
| End Page | 241 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20802540 |
| Web of Science KeyUT | 000281384400004 |
| JaLCDOI | 10.18926/AMO/40130 |
|---|---|
| FullText URL | 64_4_225.pdf |
| Author | Ohtsu, Tadahiro| Kokaze, Akatsuki| Shimada, Naoki| Kaneita, Yoshitaka| Shirasawa, Takako| Ochiai, Hirotaka| Hoshino, Hiromi| Takaishi, Masahiro| |
| Abstract | Over the past two decades, the liquor industry in Japan has strived to address alcohol-related problems through initiatives such as warnings in the various media. In this study, we conducted an Internet-based questionnaire survey to examine general consumer awareness of such warnings, and the media by which they are conveyed, on the consumption of alcoholic beverages. A total of 985 subjects (males:487, females:498) in age groups ranging from 20s to 70s responded (response rate:22.4%). The awareness rates for warnings regarding underage drinking, drunk driving, and drinking during pregnancy, and those for messages encouraging moderation in drinking, were 96.4%, 83.7%, 59.6%, and 45.5%, respectively. Logistic regression analysis adjusted for habitual alcohol consumption demonstrated significant gender- and/or age-based differences in the rates of awareness of warnings and the media publicizing them. For example, the odds ratio of awareness among women of warnings against underage drinking was significantly higher than that of awareness among men. Issues that must be addressed in the future include:(1) increasing public awareness about messages regarding drinking during pregnancy and drinking in moderation;(2) reviewing the wording of warnings to make them more effective;and (3) devising and employing, on a regular basis, more effective means of transmitting messages in consideration of gender and age. |
| Keywords | alcoholic beverages warnings consumer awareness Internet-based survey |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-08 |
| Volume | volume64 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 225 |
| End Page | 232 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20802539 |
| Web of Science KeyUT | 000281384400003 |
| JaLCDOI | 10.18926/AMO/40129 |
|---|---|
| FullText URL | 64_4_219.pdf |
| Author | Doi, Maho| Miyazaki, Ikuko| Nagamachi, Tomoko| Shinomiya, Kazuaki| Matsunaga, Hisashi| Sendo, Toshiaki| Kawasaki, Hiromu| Asanuma, Masato| Gomita, Yutaka| Kitamura, Yoshihisa| |
| Abstract | We examined the influence of chronic adrenocorticotropic hormone (ACTH) treatment on the number of Ki-67-positive cells in the dentate gyrus of the hippocampus in rats. ACTH treatment for 14 days decreased the number of such cells. The administration of imipramine or lithium alone for 14 days had no effect in saline-treated rats. The effect of ACTH was blocked by the administration of imipramine. Furthermore, the coadministration of imipramine and lithium for 14 days significantly increased the number of Ki-67-positive cells in both the saline and ACTH-treated rats. The coadministration of imipramine and lithium normalized the cell proliferation in the dentate gyrus of the hippocampus in rats treated with ACTH. |
| Keywords | ACTH imipramine lithium proliferation Ki-67 |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-08 |
| Volume | volume64 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 219 |
| End Page | 223 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20802538 |
| Web of Science KeyUT | 000281384400002 |
| JaLCDOI | 10.18926/AMO/40128 |
|---|---|
| FullText URL | 64_4_213.pdf |
| Author | Otani, Hiroyuki| Otsuka, Fumio| Inagaki, Kenichi| Suzuki, Jiro| Makino, Hirofumi| |
| Abstract | Aldosterone production occurs in the adrenal cortex, and is regulated primarily by angiotensin II (Ang II), potassium and adrenocorticotropin (ACTH). In the presence of the aldosterone stimulators, steroidogenesis is further governed by local autocrine and/or paracrine factors in the adrenal cortex. We reported the presence of functional bone morphogenetic protein (BMP) system in the adrenal cortex and also demonstrated that BMP-6 increases Ang II-induced aldosterone production, which could be involved in the "aldosterone breakthrough" phenomenon. Aldosterone breakthrough is the phenomenon by which circulating aldosterone concentrations increase above pre-treatment levels after long-term therapy with ACE inhibitors or Ang II type 1 receptor antagonists (ARB). This phenomenon may lead to important clinical consequences since increased aldosterone in a high-salt state facilitates cardiovascular and renal damage in hypertensive patients. We found that long-term ARB treatment reverses the reduction of aldosterone synthesis by adrenocortical cells, thereby causing "cellular aldosterone breakthrough". The availability of BMP-6 in the adrenal cortex may be at least partly involved in the occurrence of cellular escape from aldosterone suppression under chronic treatment with ARB. |
| Keywords | adrenal cortex angiotensin II aldosterone bone morphogenetic protein |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-08 |
| Volume | volume64 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 213 |
| End Page | 218 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20802537 |
| Web of Science KeyUT | 000281384400001 |
| Author | 岡山大学温泉研究所| |
|---|---|
| Published Date | 1974-03-25 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume43 |
| Content Type | Others |
| Author | 岡山大学大学院教育学研究科| |
|---|---|
| Published Date | 2010-06-25 |
| Publication Title | 岡山大学大学院教育学研究科研究集録 |
| Volume | volume144 |
| Content Type | Others |
| JaLCDOI | 10.18926/bgeou/40068 |
|---|---|
| Title Alternative | A Gender-Based Study of Word-Pairs in Richardson's Pamela |
| FullText URL | bgeou_144_075_083.pdf |
| Author | Wakimoto, Kyoko| |
| Abstract | English has a multitude of word-pairs based on gender differences. In their usage, however, many of the paired words have not been treated equally in a strict sense as can typically be seen in the case of 'man' and 'woman.' The present article discusses the most basic issue of masculine and feminine tenns mainly through a historical perspective. Our linguistic material here is Samuel Richardson's Pamela (1740) which offers good examples to show gender and class differences of address forms; for its theme concerns a maid-servant's conflict against her master and his equals. We hope to explore the author's social attitudes reflected in his choice of gender-specific words. |
| Keywords | 対語 ジェンダー pamela 呼称 18世紀 |
| Publication Title | 岡山大学大学院教育学研究科研究集録 |
| Published Date | 2010-06-25 |
| Volume | volume144 |
| Start Page | 75 |
| End Page | 83 |
| ISSN | 1883-2423 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002314156 |
| JaLCDOI | 10.18926/AMO/40014 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Sugimoto, Yoshihisa| Ito, Yasuo| Tomioka, Masao| Shimokawa, Tetsuya| Shiozaki, Yasuyuki| Mazaki, Tetsuro| Tanaka, Masato| |
| Abstract | Correct screw placement is especially difficult in the upper thoracic vertebrae. At the cervicothoracic junction (C7-T2), problems can arise because of the narrowness of the pedicle and the difficulty of using a lateral image intensifier there. Other upper thoracic vertebrae (T3-6) pose a problem for screw insertion also because of the narrower pedicle. We inserted 154 pedicle screws into 78 vertebrae (C7 to T6) in 38 patients. Screws were placed using intraoperative data acquisition by an isocentric C-arm fluoroscope (Siremobile Iso-C3D) and computer navigation. Out of 90 pedicle screws inserted into 45 vertebrae between C7 and T2, 87 of the 90 (96.7%) screws were classified as grade 1 (no perforation). Of 64 pedicle screws inserted into 33 vertebrae between T3 and T6, 61 of 64 (95.3%) screws were classified as grade 1. In this study, we reduced pedicle screw misplacement at the level of the C7 and upper thoracic (T1-6) vertebrae using the three-dimensional fluoroscopy navigation system. |
| Keywords | Iso-C3D three-dimensional fluoroscopy navigation upper thoracic pedicle screw |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-06 |
| Volume | volume64 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 209 |
| End Page | 212 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20596133 |
| Web of Science KeyUT | 000279094300008 |
| JaLCDOI | 10.18926/AMO/40013 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Miyatake, Nobuyuki| Shikata, Kenichi| Makino, Hirofumi| Numata, Takeyuki| |
| Abstract | We investigated the link between renal function as evaluated by estimated glomerular filtration rate (eGFR) and metabolic syndrome in Japanese. A total of 11,711 Japanese subjects, aged 20-79 years, were recruited in a cross-sectional clinical investigation. From this group, we further investigated the data on 1,576 subjects. eGFR was calculated using serum creatinine (Cr), age and sex. The diagnosis of metabolic syndrome was based on the Japanese criteria. In the first analysis, 288 men (7.8%) and 498 women (6.2%) were diagnosed with reduced eGFR (<60ml/min). eGFR was not correlated with anthropometric, body composition parameters in either sex. In the second analysis, in subjects without medications, 132 men (20.8%) and 15 women (1.6%) were diagnosed with metabolic syndrome. eGFR was lower in men with abdominal obesity and in women with hypertension was than in those without. Among Japanese not taking medications, lower eGFR may be a characteristic of men with abdominal obesity and of women with hypertension. |
| Keywords | metabolic syndrome estimated glomerular filtration rate (eGFR) abdominal circumference |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-06 |
| Volume | volume64 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 203 |
| End Page | 208 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20596132 |
| Web of Science KeyUT | 000279094300007 |
| JaLCDOI | 10.18926/AMO/40012 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Sasaki, Kentaro| Senda, Masuo| Nishida, Keiichiro| Ota, Haruyuki| |
| Abstract | We examined whether the preoperative time required for the Timed "Up and Go" (TUG) test could predict the risk for deep venous thrombosis (DVT) in patients with hip osteoarthritis after total hip arthroplasty (THA). Eighteen patients with DVT diagnosed by venography were selected, and 18 without DVT of the same age and sex and with the same operated side as the DVT group were selected as a control group. We evaluated the 5 preoperative factors that might affect the occurrence of DVT complications, as follows:disease duration, body mass index, serum total cholesterol, subjective pain evaluated by the visual analog scale, and TUG. The JOA hip score (pain, range of motion, walking ability, and daily life) was also evaluated before surgery. As a postoperative factor, we checked the postoperative day when weight-bearing was initiated. As a result, TUG (DVT, 18.4+/-4.0 sec vs. control, 15.0+/-3.2 sec;p0.01) was only significantly different between the 2 groups. The ROC curve revealed that the cut-off point of 15.3 sec in preoperative time for TUG was sensitive (83.3%) and specific (61.1%) for DVT after THA (odds ratio7.0;95% confidence interval, 1.6-30.8). These results suggested that low preoperative ambulatory ability in patients with hip osteoarthritis might be associated with DVT after THA. An improvement in TUG before surgery might contribute to a decrease in the occurrence of DVT after THA. |
| Keywords | preoperative Timed “Up and Go” test deep venous thrombosis total hip arthroplasty hip osteoarthritis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-06 |
| Volume | volume64 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 197 |
| End Page | 201 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20596131 |
| Web of Science KeyUT | 000279094300006 |
| JaLCDOI | 10.18926/AMO/40011 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Honda, Mitsugi| Arita, Seizaburo| Mitani, Shigeru| Takeda, Yoshihiro| Ozaki, Toshifumi| Inamura, Keiji| Kanazawa, Susumu| |
| Abstract | Plain X-ray radiography is frequently used for the diagnosis of developmental dislocation of the hip (DDH). The aim of this study was to construct a diagnostic support system for DDH based on clinical findings obtained from the X-ray images of 154 female infants with confirmed diagnoses made by orthopedists. The data for these subjects were divided into 2 groups. The Min-Max method of nonlinear analysis was applied to the data from Group 1 to construct the diagnostic support system based on the measurement of 4 items in X-ray images:the outward displacement rate, upward displacement rate, OE angle, and alpha angle. This system was then applied to the data from Group 2, and the results were compared between the 2 groups to verify the reliability of the system. We obtained good results that matched the confirmed diagnoses of orthopedists with an accuracy of 85.9%. |
| Keywords | X-ray image developmental dislocation of the hip acetabular dysplasia radiographic findings nonlinear multivariate analysis infant hip joint diagnostic support system |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-06 |
| Volume | volume64 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 189 |
| End Page | 196 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20596130 |
| Web of Science KeyUT | 000279094300005 |
| JaLCDOI | 10.18926/AMO/40010 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Yuzurio, Syota| Horita, Naokatsu| Shiota, Yutaro| Kanehiro, Arihiko| Tanimoto, Mitsune| |
| Abstract | We studied clinical and radiographic features of interstitial lung disease (ILD) during trimethoprim/sulfamethoxazole (TMP/SMX) administration. Ten patients who had received prednisolone treatment for underlying diffuse pulmonary disease showed various ILDs after introduction of TMP/SMX. The radiographic features of the ILDs were not consistent with infectious disease or exacerbation of the underlying disease, and these diagnoses were excluded radiographically and on clinical grounds during the differential diagnosis of the ILDs. These ILDs emerged relatively early after introduction of TMP/SMX, which is consistent with the former case report of drug-induced ILD (DI-ILD) caused by TMP/SMX. Therefore DI-ILDs caused by TMP/SMX were suspected in these cases. In most of these cases, the ILDs were clinically mild and disappeared immediately although administration of TMP/SMX was continued. |
| Keywords | drug-induced interstitial lung disease trimethoprim/sulfamethoxazole clinical characteristic radiographic findings |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-06 |
| Volume | volume64 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 181 |
| End Page | 187 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20596129 |
| Web of Science KeyUT | 000279094300004 |
| JaLCDOI | 10.18926/AMO/40009 |
|---|---|
| FullText URL | 64_3_171.pdf |
| Author | Kodama, Tomoe| Nakase, Katsumi| Tsuda, Toshihide| Yorifuji, Takashi| Doi, Hiroyuki| |
| Abstract | Physicians should educate patients with sexually transmitted infections (STIs) on measures to prevent reinfection and should also undertake human immunodeficiency virus (HIV) testing after diagnosis of STIs. These preventive measures are important, but it is not known to what extent these procedures are followed in Japan. We conducted a cross-sectional study to investigate the proportion of patients with STIs who received appropriate management from physicians, namely recommendation of HIV testing, encouragement of condom use and examination and/or treatment of sexual partners, to elucidate the factors affecting institution of each measure. From a mailshot of 566 physicians, 409 (72.3%) responded, with 176 diagnosing an STI in 967 patients. The proportions applying the 3 measures were low (recommendation of HIV testing:27.0;encouragement of condom use:64.8%;examination of sexual partners:17.5%), and were related to the sex of the patients and numbers of patients diagnosed by the physicians. Female patients received better care than male patients, particularly with respect to recommendation of HIV testing (odds ratio:2.82). Physicians who diagnosed more than 20 STI patients tended not to provide appropriate management. These findings suggest the necessity for better physician management of patients for effective prevention of STIs. |
| Keywords | sexually transmitted infections patient care management human immunodeficiency virus testing physician |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-06 |
| Volume | volume64 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 171 |
| End Page | 179 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20596128 |
| Web of Science KeyUT | 000279094300003 |
