result 13393 件
| JaLCDOI | 10.18926/OER/40545 |
|---|---|
| FullText URL | oer_036_4_193_201.pdf |
| Author | Okamoto, Akira| |
| Abstract | With a population that is aging faster than any other in the world, Japan faces serious public finance problems, particularly when it comes to tax and social security issues. The structural reforms are urgently needed to accommodate the impending demographic change. We look at the Japanese tax and social security systems through a life−cycle general equilibrium simulation model. We aim to establish guidelines for fiscal reform in Japan’s graying society and use such advanced modeling techniques to permit the calculation of the effects of alternative tax policies on capital accumulation and economic welfare. We also examine the impact of progressive expenditure taxation, coming to the novel conclusion that this form of taxation may hold the key to overcoming the large welfare loss Japan faces as its society ages under the current tax system. Furthermore, we present the concrete measures of implementing progressive expenditure taxation. |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2005-03-10 |
| Volume | volume36 |
| Issue | issue4 |
| Start Page | 193 |
| End Page | 201 |
| ISSN | 0386-3069 |
| Related Url | http://www.e.okayama-u.ac.jp/gakkai/ |
| language | English |
| File Version | publisher |
| NAID | 120002576165 |
| JaLCDOI | 10.18926/OER/40542 |
|---|---|
| FullText URL | oer_036_4_155_166.pdf |
| Author | Kurokawa, Katsutoshi| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2005-03-10 |
| Volume | volume36 |
| Issue | issue4 |
| Start Page | 155 |
| End Page | 166 |
| ISSN | 0386-3069 |
| Related Url | http://www.e.okayama-u.ac.jp/gakkai/ |
| language | English |
| File Version | publisher |
| NAID | 120002576163 |
| JaLCDOI | 10.18926/OER/40540 |
|---|---|
| FullText URL | oer_036_4_127_138.pdf |
| Author | Furumatsu, Noriko| Shirai, Masatoshi| |
| Abstract | We consider a society which consists of two sectors, the educational sector and the production sector. We define the educational sector as one that produces two outputs jointly, higher education forming human capital and research increasing the stock of social knowledge. Social knowledge determines the level of technology in the production of consumption goods. Our purposes are to clarify the nature of higher education and to analyze efficient resource allocation in a two−sector economy, considering the external effects of education and research activities in the context of an endogenous growth model. |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2005-03-10 |
| Volume | volume36 |
| Issue | issue4 |
| Start Page | 127 |
| End Page | 138 |
| ISSN | 0386-3069 |
| Related Url | http://www.e.okayama-u.ac.jp/gakkai/ |
| language | English |
| File Version | publisher |
| NAID | 120002576161 |
| JaLCDOI | 10.18926/OER/40536 |
|---|---|
| FullText URL | oer_036_4_029_038.pdf |
| Author | Wada, Junzo| |
| Abstract | Capacity management has one of the most important issues for management accounting and cost management. It has huge accumulation of theoretical and empirical research through the 20th century. In other words, there remain many inextricable disputes on capacity management. Turning to the real business world, we must solve a variety of challenges from strategic mixture of company resources and measurement for their components. Now, capacity is the value−creating ability of an organization. Its ability comes from proper shapes of capacity and cost management system. This paper shows that measurement concept and techniques for capacity costing from historical background are mainly focusing on physical asset. Adding to that, central issue has been around the distribution of unused capacity cost to products. Today’s view of capacity cost management is reinforced to notify forward−looking not retrospective. In this meaning, this paper addresses that capacity cost management should provide supportive instruments in current and future utilization of capacity including nonphysical asset. |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2005-03-10 |
| Volume | volume36 |
| Issue | issue4 |
| Start Page | 29 |
| End Page | 38 |
| ISSN | 0386-3069 |
| Related Url | http://www.e.okayama-u.ac.jp/gakkai/ |
| language | English |
| File Version | publisher |
| NAID | 120002576157 |
| JaLCDOI | 10.18926/OER/40535 |
|---|---|
| FullText URL | oer_036_4_015_027.pdf |
| Author | Haruna, Shoji| |
| Abstract | We investigate R&D behavior of public firms by using oligopoly models with Cournot−type−quantity and Bertrand−type−price competition. Then the following results are obtained. When public and private firms in a mixed oligopoly market are involved in quantity competition, (i) the public firm has a greater incentive to invest in cost−reducing R&D in a public monopoly market than in that market if they are substitutes, and (ii) the public firm has a less incentive to invest in R&D in the oligopoly market if they are complements. Furthermore, suppose that public and private firms in a mixed oligopoly market are involved in price competition. (i) If the products are complements, then a public firm has a greater incentive to invest in cost−reducing R&D in the public monopoly market than in the mixed oligopoly market; and (ii) if they are substitutes, then the public firm has a less incentive to invest in cost−reducing R&D in the public monopoly market than in the mixed oligopoly market. |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2005-03-10 |
| Volume | volume36 |
| Issue | issue4 |
| Start Page | 15 |
| End Page | 27 |
| ISSN | 0386-3069 |
| Related Url | http://www.e.okayama-u.ac.jp/gakkai/ |
| language | English |
| File Version | publisher |
| NAID | 120002576156 |
| JaLCDOI | 10.18926/OER/40530 |
|---|---|
| FullText URL | oer_036_3_001_025.pdf |
| Author | Shimizu, Koichi| |
| Abstract | One of the widely held opinions about Japanese firms’ high performance suggests that Japanese employees, organized in teams, are making kaizen (continuous improvements) in their own jobs through quality circles or other initiatives such as a suggestion system. But who are these employees? They would have to be blue−collar workers in the Western perception, but the part of their contribution in improving productivity and price cost does not seem exceed 10% of all improvements obtained. Who then brings about the major part of these improvements? Are the kaizen activities carried out without having relation to the company’s profit strategy? If the employees have an objective in their kaizen activities, who provides the objectives? What do these objectives consist of? How are their activities managed? These questions invite us to inquire about a whole management system of kaizen at Toyota Production System, considered as the basic model of “Lean Production”. But Toyota reoriented its organized kaizen activities toward the construction of more humanized production system during 1990s. This paper then shows this reorientation and the new direction by showing the case of Tahara No.1 plant. Through these discussions, I want to emphasize the importance of organized kaizen activities that group leaders, chief leaders and engineers are carrying out, and also the fact that their activities are now centered not only upon productivity increase but also upon the humanization of work. |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2004-12-10 |
| Volume | volume36 |
| Issue | issue3 |
| Start Page | 1 |
| End Page | 25 |
| ISSN | 0386-3069 |
| Related Url | http://www.e.okayama-u.ac.jp/gakkai/ |
| language | English |
| File Version | publisher |
| NAID | 120002576151 |
| JaLCDOI | 10.18926/OER/40527 |
|---|---|
| FullText URL | oer_036_2_035_048.pdf |
| Author | Yokoo, Masanori| |
| Abstract | This note considers a situation in which the publisher of an academic journal seeks to maintain the number of contributions to the journal by subsidizing the contributors with some incentive payments. We show that under the incentive payment scheme that distributes some pre−determined total amount of payments equally to each contributor (the constant total payment scheme), the number of contributions can fluctuate cyclically as well as chaotically over time when the potential contributors form adaptive expectations. Numerical simulations suggest, among other things, that the performance of the constant total payment scheme may be more efficient than the constant per−capita payment scheme when the total amount of payments is supposed to be small. |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2004-09-10 |
| Volume | volume36 |
| Issue | issue2 |
| Start Page | 35 |
| End Page | 48 |
| ISSN | 0386-3069 |
| Related Url | http://www.e.okayama-u.ac.jp/gakkai/ |
| language | English |
| File Version | publisher |
| NAID | 120002576148 |
| JaLCDOI | 10.18926/OER/40520 |
|---|---|
| FullText URL | oer_036_1_001_011.pdf |
| Author | Takemura, Shosuke| |
| Abstract | The view about a certain mixed structure with monopoly and competition is the typical subject. Morishima found that the patterns of deciding price are dependent on the main types of price mechanism. I’ll test Morishima’s postulate through use of the recent data. We can consider the relative difference between the manufacturing sector and the agricultural sector in deciding the market price. Especially I am interested in the institutions and features of deciding and changing price in using the mark-up principle under the monopolistic pressures namely, in the circumstances we call rivalry. Concretely those are realized under the fixed, flexible and mixed price economies. The mark-up principle is closely related to the ratio between two sectors in the fixed price economy. Schumpeter told us that the clever firm is able to use his wisdom thoughtfully and effectively by creating, processing his own pricing method and innovational knowledge in R&D. |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2004-06-10 |
| Volume | volume36 |
| Issue | issue1 |
| Start Page | 1 |
| End Page | 11 |
| ISSN | 0386-3069 |
| Related Url | http://www.e.okayama-u.ac.jp/gakkai/ |
| language | English |
| File Version | publisher |
| NAID | 120002576142 |
| JaLCDOI | 10.18926/OER/40518 |
|---|---|
| FullText URL | oer_037_4_001_012.pdf |
| Author | Kurokawa, Katsutoshi| |
| Abstract | The aim of this article is to examine the change of the relationship between the American labor movement and Japanese communities in the Pacific Northwest in the 1930s. The relationship between the American labor movement and Japanese communities in the Pacific Northwest in the early 1930s was not a friendly one. Most labor organizations continued to reject Japanese workers. White workers, suffering as a result of the Great Depression, were often hostile to the Japanese. The attitudes of Japanese communities toward the labor movement were also not favorable ones. However, some people : Kazue Miyata, Yoshiaki Yamane, Gentaro Oe, and many other unknown activists, continued to believe in the importance of the organization of Japanese workers and committed themselves to the cause of the labor movement in this difficult situation. The situation began to change in the mid−1930s. The start of the NIRA regime made Japanese communities reconsider the significance of the organization of workers in the United States. The development of the CIO lowered barriers for Japanese workers to join unions throughout the United States. Moreover, the general development of the labor movement in the United States, which was stimulated by the enactment of the NIRA and the Wagner Act, of course, affected Japanese communities too. In response to such conditions, the Japanese Restaurant Workers’ Union was organized in around 1936 in Seattle. In the canned−salmon industry in which many Asians were working, the Cannery Workers and Farm Laborers Union was organized in 1933. This union was organized by Filipino workers, but, before long, Japanese and Chinese workers also took part in it. By the beginning of the 1940s, as Daisho Miyagawa stated later, "the union idea was no longer novel or especially provocative of tension and controversy in the Seattle Japanese community". |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2006-03-10 |
| Volume | volume37 |
| Issue | issue4 |
| Start Page | 1 |
| End Page | 12 |
| ISSN | 0386-3069 |
| Related Url | http://www.e.okayama-u.ac.jp/gakkai/ |
| language | English |
| File Version | publisher |
| NAID | 120002576140 |
| JaLCDOI | 10.18926/AMO/40511 |
|---|---|
| FullText URL | 64_5_345.pdf |
| Author | Ishihara, Yoshihito| Kuroda, Shingo| Kawanabe, Noriaki| Takano-Yamamoto, Teruko| Yamashiro, Takashi| |
| Abstract | This article reports the successful surgical-orthodontic treatment of an elderly patient with dentofacial deformity and signs and symptoms of temporomandibular disorder (TMD). The patient was a 63-year-old woman with a concave profile due to mandibular protrusion. To correct skeletal deformities, the mandible was posteriorly repositioned by employing intraoral vertical ramus osteotomy (IVRO) following presurgical orthodontic treatment. After active treatment for 31 months, the facial profile was significantly improved and satisfactory occlusion was achieved. In addition, TMD symptoms of clicking sounds on the left side and difficulty in mouth opening were resolved. Regarding the findings of magnetic resonance imaging, anterior disc displacement in the opening phase was improved in the temporomandibular joint on the left side. Furthermore, stomatognathic functions were also improved without any aggravation of age-related problems. In conclusion, surgical repositioning of the mandible using IVRO leads to both morphological and functional improvements even in elderly patients. |
| Keywords | elderly patient orthodontics temporomandibular disorder intraoral vertical ramus osteotomy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 345 |
| End Page | 349 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975769 |
| Web of Science KeyUT | 000283563300011 |
| JaLCDOI | 10.18926/AMO/40510 |
|---|---|
| FullText URL | 64_5_339.pdf |
| Author | Miyatake, Nobuyuki| Shikata, Kenichi| Makino, Hirofumi| Numata, Takeyuki| |
| Abstract | The link between changes in a subject's metabolic syndrome components and her estimated glomerular filtration rate (eGFR) was evaluated in healthy Japanese women. We used data for 53 Japanese women (46.0±10.9 years) with a 1-year follow up. eGFR was defined by a new equation developed for Japan. There were no significant relationships between eGFR and clinical parameters at baseline. Subjects were given advice for dietary and lifestyle improvement. At the 1-year follow up, eGFR was significantly increased. In addition, changes in eGFR were weakly correlated with systolic blood pressure(r＝－0.306, p＝0.0260). A decrease in systolic blood pressure may be associated with improving eGFR in Japanese women. |
| Keywords | systolic blood pressure estimated glomerular filtration rate (eGFR) metabolic syndrome lifestyle modification |
| Amo Type | Short Communication |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 339 |
| End Page | 343 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975768 |
| Web of Science KeyUT | 000283563300010 |
| JaLCDOI | 10.18926/AMO/40509 |
|---|---|
| FullText URL | 64_5_331.pdf |
| Author | Park, Se-Jin| Jung, Young-Bok| Jeong, Hwa Jae| Shin, Hun-Kyu| Jung, Ho-Joong| Lim, Jong-Jun| Yoon, Ji-Woong| Kim, Eugene| |
| Abstract | Among patients that underwent total knee arthroplasty from June, 1990 to January, 1999, 61 cases (44 patients) that could be followed for more than 10 years were included in this study. The patients were divided into a patellar retention group and a patellar resurfacing group, and were compared with regard to their clinical and radiological outcomes. In patients undergoing primary TKA, a selective patellar resurfacing protocol was used. The indications for patellar retention were a small patella, nearly normal articular cartilage, minimal preoperative patellofemoral pain, poor patellar bone quality, and young patient age. When patellar retention was performed, osteophytes of the patella were removed and marginal electrocauterization was carried out. There were 25 cases (20 patients) in the patellar retention group and 36 cases (29 patients) in the patellar resurfacing group. The mean follow-up period was 140.7 months in the patellar retention group and 149.0 months in the patellar resurfacing group. The selective patellar resurfacing with total knee arthroplasty had a favorable outcome;there were a significant difference noted between the 2 groups in the functional scores, which showed better outcomes in the patellar resurfacing group than in the patellar retention group. |
| Keywords | total knee arthroplasty (TKA) selective patellar resurfacing patellar retention patellar resurfacing |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 331 |
| End Page | 338 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975767 |
| Web of Science KeyUT | 000283563300009 |
| JaLCDOI | 10.18926/AMO/40508 |
|---|---|
| FullText URL | 64_5_323.pdf |
| Author | Kanaoka, Yuji| Inagaki, Ei-ichirou| Hamanaka, Souhei| Masaki, Hisao| Tanemoto, Kazuo| |
| Abstract | The transient systemic low perfusion that occurs during cardiovascular surgery leads to oxidative stress and the production of free radicals. A systemic increase of various markers of oxidative stress has been shown to occur during cardiopulmonary bypass (CPB). However, these markers have not been adequately evaluated because they seem to be reactive and short-lived. Here, oxidative stress was measured using the free radical analytical system (FRAS 4) assessing the derivatives of reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP). Blood samples were taken from 21 patients undergoing elective cardiovascular surgery. CPB was used in 15 patients, and abdominal aortic aneurysm (AAA) surgery without CPB was performed in 6. Measurements of d-ROMs and BAP were taken before surgery, 1 day, 1 week, and 2 weeks after surgery, and oxidative stress was evaluated. The d-ROM level increased gradually after cardiovascular surgery up to 2 weeks. Over time, the d-ROM level after surgery involving CPB became higher than that after AAA surgery. This difference reached statistical significance at 1 week and lasted to 2 weeks. The prolongation of CPB was prone to elevate the d-ROM level whereas the duration of the aortic clamp in AAA surgery had no relation to the d-ROM level. The BAP was also elevated after surgery, and was positively correlated with the level of d-ROMs. In this study, patients who underwent cardiovascular surgery involving CPB had significant oxidative damage. The production of ROMs was shown to depend on the duration of CPB. Damage can be reduced if CPB is avoided. When CPB must be used, shortening the CPB time may be effective in reducing oxidative stress. |
| Keywords | oxidative stress reactive oxygen metabolites (ROM) extracorporeal circulation (ECC) |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 323 |
| End Page | 330 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975766 |
| Web of Science KeyUT | 000283563300008 |
| JaLCDOI | 10.18926/AMO/40507 |
|---|---|
| FullText URL | 64_5_317.pdf |
| Author | Myo-Khin| San-San-Oo| Khin, May Oo| Shimono, Kunio| Koide, Norio| Okada, Shigeru| |
| Abstract | We studied the prevalence of hepatitis C virus infection among blood donors from 3 hospitals of Central Myanmar and 7 hospitals of Lower Myanmar in the Yangon area, and analyzed the factors associated with the infection. The study period was from November, 2005 to June, 2007. A pre-tested questionnaire was used to obtain information on age, ethnic group, marital status, tattooing, body piercing, history of receiving transfusions, and liver diseases in self and in sexual partners. Data on seropositivity to hepatitis C, hepatitis B and human immunodeficiency virus infections were recorded. A total of 65,240 blood donors participated in the study. Their ages ranged from 18 years to 60 years (mean±SD＝29.5±9.3). The male-to-female ratio was 6：1. The prevalence of the antibody to hepatitis C was found to be 0.95% with varying rates (0.34 to 2.03) among hospitals. Females had a slightly higher rate (1.06%) than males (0.93%) (p＝0.237). Multivariate analyses revealed the following factors to be related to HCV infection:HIV infection, odds ratio (OR)＝3.0 (p＝0.003);history of liver disease, OR＝8.9 (p＝0.001);and age 30 years and above, OR＝2.6 (p＝0.001). We discuss the varying prevalences of HCV around the world. |
| Keywords | Myanmar hepatitis C prevalence blood donors associated factors |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 317 |
| End Page | 321 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975765 |
| Web of Science KeyUT | 000283563300007 |
| JaLCDOI | 10.18926/AMO/40506 |
|---|---|
| FullText URL | 64_5_307.pdf |
| Author | Kang, Hyun| Cha, Su-Man| Park, Sun-Gyoo| Jung, Yong-Hun| Woo, Young-Cheol| Kim, Jin-Yun| Koo, Gill-Hoi| Kim, Seong-Deok| Baek, Chong-Wha| |
| Abstract | It is not known whether changing from isoflurane to desflurane during the latter part of anesthesia shows early emergence and recovery in long surgery. We therefore evaluated the effects of changing isoflurane to desflurane on emergence and recovery. Eighty-two patients were randomly assigned to receive isoflurane (Group I) or desflurane (Group D) or to change from isoflurane to desflurane anesthesia (Group X). At the point when there was an hour until the operation would end, isoflurane was replaced with 1 MAC of desflurane in Group X, and isoflurane and desflurane were maintained at 1 MAC in Groups I and D. When the operation ended, we compared the emergence and recovery characteristics among the 3 groups. Compared with Group I, Group X showed faster emergence and recovery. Group X and Group D showed similar emergence and recovery. In conclusion, changing isoflurane to desflurane during the latter part of anesthesia improves emergence and recovery. |
| Keywords | desflurane isoflurane laparotomy recovery |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 307 |
| End Page | 316 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975764 |
| Web of Science KeyUT | 000283563300006 |
| JaLCDOI | 10.18926/AMO/40505 |
|---|---|
| FullText URL | 64_5_299.pdf |
| Author | Sanomura, Takayuki| Ikeda, Fusao| Katoh, Tsutomu| Hosokawa, Kazue| Suzuki, Seiyuu| Nishiyama, Yoshihiro| |
| Abstract | Tumor protrusion in hepatocellular carcinoma (HCC) is one of the risk signs of tumor rupture. Despite curative tumor treatments, HCC recurrences sometimes occur with rapidly growing humped or ruptured HCC in small sized tumors. The aim of this study was to clarify the characteristics of humped HCC clinically and radiologically associated with tumor progression, liver damage, and treatment. The subjects were 179 consecutive HCC patients who underwent angiographic examination. Dynamic studies, using helical computed tomography and magnetic resonance imaging were assessed, and the HCC area were measured. The tumor-node-metastasis (TNM) stage differed significantly between the humped and non-humped HCC groups. Humped HCC was more frequently observed in the right lobe (29.3% of right-lobe HCCs) than in the left (10.1%;p＝0.003). Analysis of recurrent HCC revealed that patients with multiple treatments of >4 sessions had more humped HCC (33.8%) than those with 1-3 sessions (16.7%;p＝0.042). Multivariate regression analysis revealed that tumor invasion in the portal vein, rather than large tumor size, was significantly associated with tumor protrusion. HCC recurrence with humped HCC occurs often in patients with multiple treatments. Tumor factors of the TNM classification, especially tumor invasion in the portal vein, might be associated with the mechanisms of tumor protrusion. |
| Keywords | humped HCC tumor protrusion |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 299 |
| End Page | 305 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975763 |
| Web of Science KeyUT | 000283563300005 |
| JaLCDOI | 10.18926/AMO/40504 |
|---|---|
| FullText URL | 64_5_293.pdf |
| Author | Sugimoto, Yoshihisa| Ito, Yasuo| Tomioka, Masao| Shimokawa, Tetsuya| Shiozaki, Yasuyuki| Mazaki, Tetsuro| Tanaka, Masato| |
| Abstract | We used a navigation system to insert 128 pedicle screws into 69 vertebrae (L1 to L3) of 49 consecutive patients. We assessed the pedicle isthmic width and the permission angle for pedicle screw insertion. The permission angle is the angle defined by the greatest medial and lateral trajectories allowable when placing the screw through the center of the pedicle. The rate of narrow-width pedicles (isthmic width less than 5mm) was 5 of 60 pedicles (8%) at L1, 4 of 60 pedicles (7%) at L2, and none (0%) at L3, L4 and L5. The rate of narrow-angle pedicles (a permission angle less than 15 degrees) was 21 of 60 pedicles (35%) at L1, 7 of 60 (12%) at L2, 3 of 60 (5%) at L3, and none (0%) at L4 and L5. Of 128 pedicle screws inserted into 69 vertebrae from L1 to L3, 125 (97.7%) were classified as Grade 1 (no pedicle perforation). In general, the upper lumbar vertebrae have more narrow-width and -angle pedicles. However, we could reduce the rate of pedicle screw misplacement in upper lumbar vertebra using a three-dimensional fluoroscopy and navigation system. |
| Keywords | upper lumbar navigation pedicle screw anatomy misplacement |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 293 |
| End Page | 297 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975762 |
| Web of Science KeyUT | 000283563300004 |
| JaLCDOI | 10.18926/AMO/40503 |
|---|---|
| FullText URL | 64_5_285.pdf |
| Author | Nishimori, Hisakazu| Takahashi, Shunji| Kiura, Katsuyuki| Ennishi, Daisuke| Kobayashi, Takayuki| Sano, Koji| Shinozaki, Eiji| Yokoyama, Masahiro| Mishima, Yuko| Terui, Yasuhito| Chin, Keisho| Mizunuma, Nobuyuki| Ito, Yoshinori| Nishimura, Seiichiro| Takeuchi, Kengo| Ishikawa, Yuichi| Oguchi, Masahiko| Tanimoto, Mitsune| Hatake, Kiyohiko| |
| Abstract | We evaluated the efficacy and toxicity of cisplatin/docetaxel (CDDP/TXT) chemotherapy and identified prognostic factors in Japanese patients with cancer of unknown primary site (CUP). Twenty-eight consecutive patients seen at a single institute were reviewed retrospectively. Sixteen patients were treated with TXT 80mg/m2, followed by CDDP 75mg/m2. The overall response rate to CDDP/TXT treatment was 62.5%, with a median survival time (MST) of 22.7 months. Common adverse reactions were myelosuppression and hyponatremia. The MST of all 28 patients with CUP was 8.3 months, and the 1-year overall survival rate was 45.6%. Univariate analysis identified 5 prognostic factors:performance status, liver involvement, bone involvement, pleural involvement, and lymph node involvement. In conclusion, CDDP/TXT chemotherapy is effective with tolerable toxicity in patients with CUP. Japanese patients with CUP might be chemosensitive and may survive longer. |
| Keywords | cancer of unknown primary site (CUP) cisplatin docetaxel prognosis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 285 |
| End Page | 291 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975761 |
| Web of Science KeyUT | 000283563300003 |
| JaLCDOI | 10.18926/AMO/40502 |
|---|---|
| FullText URL | 64_5_277.pdf |
| Author | Kumase, Fumiaki| Morizane, Yuki| Mohri, Satoshi| Takasu, Ippei| Ohtsuka, Aiji| Ohtsuki, Hiroshi| |
| Abstract | Endothelial glycocalyx (GCX) has been reported as a protective factor for vascular endothelial cells (VEC) in diabetes and hypertension. However, the involvement of GCX impairment in ocular vasculopathy remains unclear. We evaluated the changes in the GCX thicknesses of the retinal and choroidal capillaries in rats with diabetes and hypertension by cationic colloidal iron staining using a transmission electron microscope. In the control group, the mean (standard error of the mean) thicknesses of retinal and choroidal GCX were 60.2 (1.5) nm and 84.3 (3.1) nm, respectively. The diabetic rats showed a significant decrease of GCX thickness in the retina, but not in the choroid, compared to controls (28.3 (0.3) nm, p＜0.01 and 77.8 (1.4) nm, respectively). In the hypertensive rats, both retinal and choroidal GCX were significantly decreased compared to the control values (10.9 (0.4) nm and 13.2 (1.0) nm, respectively, both p＜0.01). Moreover, we could visualize the adhesion of leukocytes and platelets on the luminal surface of VEC, at the site where the GCX was markedly degraded. These findings suggest that the GCX prevents adhesion of leukocytes and platelets to the VEC surface, and this impairment may lead to ocular vasculopathy in diabetes and hypertension. |
| Keywords | glycocalyx retina choroid diabetes hypertension |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 277 |
| End Page | 283 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975760 |
| Web of Science KeyUT | 000283563300002 |
| JaLCDOI | 10.18926/AMO/40501 |
|---|---|
| FullText URL | 64_5_267.pdf |
| Author | Sagara, Hidenori| Sendo, Toshiaki| Gomita, Yutaka| |
| Abstract | In the runway model of intracranial self-stimulation (ICSS) experimentation, the experimental animal is timed in running a fixed distance to depress a lever that releases electrical stimulation to an electrode implanted along its medial forebrain bundle. This ICSS has both a reward and a motivational component. Using the runway method and priming stimulation, we designed an experimental method for directly measuring motivation. An assessment of pharmacological agents that are known to influence motivational states was also undertaken. Using the experimental methods that we created, we observed prominent changes in running speed when animals were exposed to methamphetamine and nicotine. According to these data, the runway method employing intracranial self-stimulation behavior may be useful for the evaluation of substances that act on motivation. We review the underlying neuropharmacological and anatomical functions associated with our experimental methods. We hope that this technique will be used to scientifically evaluate the impact of drugs and/or therapeutic interventions on human motivation. |
| Keywords | intracranial self-stimulation behavior motivational effect methamphetamine nicotine |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-10 |
| Volume | volume64 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 267 |
| End Page | 275 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2010 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20975759 |
| Web of Science KeyUT | 000283563300001 |
