Author Hagiya, Hideharu| Tokumasu, Kazuki| Otsuka, Yuki| Sunada, Naruhiko| Nakano, Yasuhiro| Honda, Hiroyuki| Furukawa, Masanori| Otsuka, Fumio|
Keywords Complement immunity Complement system Coronavirus disease 2019 Inflammation
Note © 2023 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Feb. 2025.|
Published Date 2024-03
Publication Title Journal of Infection and Chemotherapy
Volume volume30
Issue issue3
Publisher Elsevier
Start Page 236
End Page 241
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 37866620
DOI 10.1016/j.jiac.2023.10.016
Web of Science KeyUT 001167908700001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2023.10.016
FullText URL fulltext.pdf
Author Tokumasu, Kazuki| Fujita-Yamashita, Manami| Sunada, Naruhiko| Sakurada, Yasue| Yamamoto, Koichiro| Nakano, Yasuhiro| Matsuda, Yui| Otsuka, Yuki| Hasegawa, Toru| Hagiya, Hideharu| Honda, Hiroyuki| Otsuka, Fumio|
Keywords adverse events COVID-19 SARS-CoV-2 vaccination mRNA vaccine
Published Date 2023-10-30
Publication Title Vaccines
Volume volume11
Issue issue11
Publisher MDPI
Start Page 1661
ISSN 2076-393X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 38005993
DOI 10.3390/vaccines11111661
Web of Science KeyUT 001113977600001
Related Url isVersionOf https://doi.org/10.3390/vaccines11111661
FullText URL fulltext.pdf
Author Murakami, Taku| Yamamoto, Akira| Hagiya, Hideharu| Obika, Mikako| Mandai, Yasuhiro| Miyoshi, Tomoko| Kataoka, Hitomi| Otsuka, Fumio|
Keywords Medical Education Educational Measurement Simulation Training Peer Group Emergency Medicine Internship and residency Curriculum Personal satisfaction Case-control studies
Note The version of record of this article, first published in BMC Medical Education, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12909-023-04798-w|
Published Date 2023-11-12
Publication Title BMC Medical Education
Volume volume23
Issue issue1
Publisher BMC
Start Page 859
ISSN 1472-6920
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37953233
DOI 10.1186/s12909-023-04798-w
Web of Science KeyUT 001103563600006
Related Url isVersionOf https://doi.org/10.1186/s12909-023-04798-w
FullText URL fulltext20231013-02.pdf
Author Matsumoto, Naomi| Kadowaki, Tomoka| Matsuo, Rumi| Sasaki, Ayako| Miyaji, Chikara| Higuchi, Chigusa| Nakayama, Masanori| Sakurada, Yasue| Hagiya, Hideharu| Takao, Soshi| Otsuka, Fumio| Yorifuji, Takashi|
Keywords SARS-CoV-2 mRNA-1273 antibody reactogenicity adverse reaction
Published Date 2022-12-05
Publication Title Journal of Epidemiology
Volume volume32
Issue issue12
Publisher Japan Epidemiological Association
Start Page 567
End Page 569
ISSN 0917-5040
NCID AA10952696
Content Type Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Naomi Matsumoto et al.
File Version publisher
PubMed ID 36031363
DOI 10.2188/jea.je20220210
Web of Science KeyUT 000884682100001
Related Url isVersionOf https://doi.org/10.2188/jea.JE20220210
FullText URL fulltext20231016-01.pdf
Author Hagiya, Hideharu| Otsuka, Fumio|
Keywords Antimicrobial resistance Contact isolation Health care-associated infection Standard precautions
Published Date 2023-09
Publication Title American Journal of Infection Control
Volume volume51
Issue issue9
Publisher Elsevier BV
Start Page 1056
End Page 1062
ISSN 0196-6553
NCID AA10617749
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Author(s).
File Version publisher
PubMed ID 36736903
DOI 10.1016/j.ajic.2023.01.018
Web of Science KeyUT 001069295400001
Related Url isVersionOf https://doi.org/10.1016/j.ajic.2023.01.018
FullText URL fulltext.pdf
Author Soejima, Yoshiaki| Iwata, Nahoko| Nishioka, Ran| Honda, Mako| Nakano, Yasuhiro| Yamamoto, Koichiro| Suyama, Atsuhito| Otsuka, Fumio|
Keywords bone morphogenetic protein (BMP) orexin steroidogenesis and adrenal
Published Date 2023-08-08
Publication Title International Journal of Molecular Sciences
Volume volume24
Issue issue16
Publisher MDPI
Start Page 12559
ISSN 1661-6596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 37628739
DOI 10.3390/ijms241612559
Web of Science KeyUT 001056982200001
Related Url isVersionOf https://doi.org/10.3390/ijms241612559
FullText URL fulltext.pdf
Author Fukushima, Shinnosuke| Hagiya, Hideharu| Yamamoto, Yukichika| Oguni, Kohei| Hasegawa, Kou| Otsuka, Fumio|
Keywords cryptococcal meningitis Cryptococcus neoformans neurosarcoidosis interleukin-6
Published Date 2023-08-15
Publication Title Internal Medicine
Volume volume62
Issue issue16
Publisher The Japanese Society of Internal Medicine
Start Page 2433
End Page 2435
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 36575015
DOI 10.2169/internalmedicine.0879-22
Web of Science KeyUT 001051476800001
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.0879-22
JaLCDOI 10.18926/AMO/65740
FullText URL 77_4_347.pdf
Author Iwamuro, Masaya| Kondo, Takumi| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-ichi| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Maeda, Yoshinobu| Okada, Hiroyuki|
Abstract The feasibility of lymphocyte isolation and flow cytometry using a single endoscopic biopsy specimen from the gastrointestinal tract of patients who have undergone hematopoietic stem cell transplantation has not been investigated. We acquired 51 endoscopic biopsy specimens from the gastrointestinal tract of 35 patients. We divided the flow cytometry samples into two groups: group A, successful lymphocyte isolation (n=24), and group B, incomplete isolation (n=27). We compared the backgrounds of the samples between the groups to reveal crucial elements in the successful isolation of lymphocytes residing in the gastrointestinal tract. Comparison between the groups revealed lymphocyte isolation success rates differed between biopsy sites. Isolation was most successful in samples from the duodenum (8/9, 88.9%), followed by the ileum (4/8, 50.0%), large intestine (4/11, 36.4%), and stomach (8/23, 34.8%). Tacrolimus was used more frequently in group B (92.6%) than in group A (62.5%) (p=0.015). Logistic regression analysis revealed that isolation from the duodenum or ileum was a significant factor for successful isolation, while tacrolimus use was not statistically significant. In conclusion, the duodenum and ileum are more suitable sites than the stomach and colorectum for acquiring samples for flow cytometry.
Keywords flow cytometry stem cell transplantation transplantation-associated microangiopathy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 347
End Page 357
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635134
Web of Science KeyUT 001163659800002
FullText URL fulltext20230817-04.pdf fig20230817-04.pdf table20230817-04.pdf
Author Hagiya, Hideharu| Nishimura, Yoshito| Otsuka, Fumio|
Keywords Amphotericin B Fungal infection Inhalation Nebulization Aerosolization
Note © 2023 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Oct. 2024.|
Published Date 2023-10
Publication Title Pulmonary Pharmacology and Therapeutics
Volume volume82
Publisher Elsevier BV
Start Page 102233
ISSN 1094-5539
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Elsevier Ltd.
File Version author
PubMed ID 37414132
DOI 10.1016/j.pupt.2023.102233
Web of Science KeyUT 001037489400001
Related Url isVersionOf https://doi.org/10.1016/j.pupt.2023.102233
FullText URL fulltext.pdf
Author Otsuka, Yuki| Hagiya, Hideharu| Sunada, Naruhiko| Otsuka, Fumio|
Keywords burnout clerical work medical assistant overwork task shift
Published Date 2023-07-25
Publication Title Journal of General and Family Medicine
Volume volume24
Issue issue5
Publisher Wiley
Start Page 317
End Page 319
ISSN 2189-7948
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
DOI 10.1002/jgf2.641
Web of Science KeyUT 001035827200001
Related Url isVersionOf https://doi.org/10.1002/jgf2.641
FullText URL fulltext.pdf
Author Oguni, Kohei| Fukushima, Shinnosuke| Yamamoto, Yukichika| Hasegawa, Kou| Hagiya, Hideharu| Inoshita, Naoko| Otsuka, Fumio|
Keywords Insulinoma octreotide test somatostatin receptor somatostatin scintigraphy
Published Date 2023-08-02
Publication Title Clinical Case Reports
Volume volume11
Issue issue8
Publisher Wiley
Start Page e7771
ISSN 2050-0904
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 37546161
DOI 10.1002/ccr3.7771
Web of Science KeyUT 001039569500001
Related Url isVersionOf https://doi.org/10.1002/ccr3.7771
FullText URL fulltext.pdf
Author Yamamoto, Yukichika| Otsuka, Yuki| Tokumasu, Kazuki| Sunada, Naruhiko| Nakano, Yasuhiro| Honda, Hiroyuki| Sakurada, Yasue| Hasegawa, Toru| Hagiya, Hideharu| Otsuka, Fumio|
Keywords COVID-19 ferritin insulin-like growth factor-I (IGF-I) long COVID myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Published Date 2023-07-18
Publication Title Journal of Clinical Medicine
Volume volume12
Issue issue14
Publisher MDPI
Start Page 4737
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 37510852
DOI 10.3390/jcm12144737
Web of Science KeyUT 001035871200001
Related Url isVersionOf https://doi.org/10.3390/jcm12144737
FullText URL fulltext.pdf
Author Hagiya, Hideharu| Uno, Mika| Higashionna, Tsukasa| Honda, Hiroyuki| Otsuka, Fumio|
Keywords antimicrobial resistance antimicrobial stewardship antibiotics weekdays weekends
Published Date 2023-06-15
Publication Title Internal Medicine
Volume volume62
Issue issue12
Publisher Japanese Society of Internal Medicine
Start Page 1739
End Page 1742
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 36288987
DOI 10.2169/internalmedicine.0707-22
Web of Science KeyUT 001015018300001
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.0707-22
FullText URL fulltext20230706-01.pdf fig1_20230706-01.pdf fig2_20230706-01.pdf suppl20230706-01.pdf
Author Kondo, Takumi| Fujii, Keiko| Fujii, Nobuharu| Sumii, Yuichi| Urata, Tomohiro| Kimura, Maiko| Matsuda, Masayuki| Ikegawa, Shuntaro| Washio, Kana| Fujiwara, Hideaki| Asada, Noboru| Ennishi, Daisuke| Nishimori, Hisakazu| Matsuoka, Ken‐ichi| Otsuka, Fumio| Maeda, Yoshinobu|
Keywords blood center operations cellular therapy therapeutic apheresis
Note This is the peer reviewed version of the following article: [Kondo T, Fujii K, Fujii N, Sumii Y, Urata T, Kimura M, et al. Efficient granulocyte collection method using high concentrations of medium molecular weight hydroxyethyl starch. Transfusion. 2023; 63(7): 1344–1353. https://doi.org/10.1111/trf.17450], which has been published in final form at [https://doi.org/10.1111/trf.17450]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in Jun. 2024.|
Published Date 2023-06-09
Publication Title Transfusion
Volume volume63
Issue issue7
Publisher Wiley
Start Page 1344
End Page 1353
ISSN 0041-1132
NCID AA00868753
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 AABB.
File Version author
PubMed ID 37293978
DOI 10.1111/trf.17450
Web of Science KeyUT 001004560100001
Related Url isVersionOf https://doi.org/10.1111/trf.17450
FullText URL fulltext20230711-01.pdf fig20230711-01.pdf
Author Takase, Ryosuke| Hagiya, Hideharu| Fujimori, Takumi| Yokoyama, Yukika| Iio, Koji| Honda, Hiroyuki| Hasegawa, Kou| Otsuka, Fumio|
Note © 2023 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jul. 2024.|
Published Date 2023-09
Publication Title Journal of Infection and Chemotherapy
Volume volume29
Issue issue9
Publisher Elsevier Ltd.
Start Page 919
End Page 921
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 37230385
DOI 10.1016/j.jiac.2023.05.017
Web of Science KeyUT 001050515100001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2023.05.017
FullText URL fulltext.pdf
Author Hagiya, Hideharu| Nakano, Yasuhiro| Furukawa, Masanori| Sunada, Naruhiko| Hasegawa, Toru| Sakurada, Yasue| Hasegawa, Kou| Yamamoto, Koichiro| Ogawa, Hiroko| Obara, Takafumi| Ageta, Kouhei| Matsumoto, Naomi| Matsuo, Rumi| Kadowaki, Tomoka| Higashikage, Akihito| Hikita, Takao| Yorifuji, Takashi| Toyooka, Shinichi| Maeda, Yoshinobu| Yokokura, Yoshinori| Otsuka, Fumio| Nakayama, Masanori|
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-022-24464-3|
Published Date 2022-11-30
Publication Title Scientific Reports
Volume volume12
Issue issue1
Publisher nature portfolio
Start Page 20628
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
PubMed ID 36450786
DOI 10.1038/s41598-022-24464-3
Web of Science KeyUT 001002757900008
Related Url isVersionOf https://doi.org/10.1038/s41598-022-24464-3
JaLCDOI 10.18926/AMO/65490
FullText URL 77_3_255.pdf
Author Fukushima, Shinnosuke| Hagiya, Hideharu| Uda, Kazuhiro| Gotoh, Kazuyoshi| Otsuka, Fumio|
Abstract Antimicrobial resistance is an emerging global threat that must be addressed using a multidisciplinary approach. This study aimed to raise awareness of high-level antimicrobial-resistant (AMR) pathogens in Japan by comparing their recent prevalences among prefectures, particularly Okayama. Data for the isolation proportions of meropenem-resistant Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, cefotaxime-resistant Escherichia coli and Klebsiella pneumoniae, and levofloxacin-resistant E. coli and K. pneumoniae were collected from the Japan Nosocomial Infections Surveillance, a national database sponsored by the Japanese Ministry of Health, Labour, and Welfare, between 2018 and 2021. The average isolated proportions of the seven AMR pathogens were higher in Okayama compared to other prefectures: the worst (19.9%) was meropenem-resistant P. aeruginosa, the sixth worst (57.2%) was methicillin-resistant S. aureus, the eighth worst (3.3%) was vancomycin-resistant E. faecium, the second (37.8%) and fifth worst (17.6%) were cefotaxime-resistant E. coli and K. pneumoniae, respectively, and the fourth (49.9%) and third worst (8.7%) were levofloxacin-resistant E. coli and K. pneumoniae, respectively. Our study highlights the notably high prevalences of representative AMR pathogens in Okayama, suggesting the need for fundamental infection prevention and control by healthcare professionals, promoting antimicrobial stewardship, and educating undergraduates and postgraduates in Okayama.
Keywords antimicrobial resistance antimicrobial stewardship epidemiology infection prevention and control Japan Nosocomial Infections Surveillance
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-06
Volume volume77
Issue issue3
Publisher Okayama University Medical School
Start Page 255
End Page 262
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37357626
Web of Science KeyUT 001026279600003
JaLCDOI 10.18926/AMO/65488
FullText URL 77_3_235.pdf
Author Kuraoka, Sakiko| Iwamuro, Masaya| Satomi, Takuya| Yamazaki, Tatsuhiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kato, Hironari| Otsuka, Fumio| Okada, Hiroyuki|
Abstract Changes in hormone levels in patients with cancer cachexia after anamorelin administration have not been fully investigated. This study aimed to determine how anamorelin affects the endocrine system in patients with gastrointestinal cancer and cachexia. We prospectively enrolled 13 patients and comprehensively investigated their body weight and levels of serum albumin, hemoglobin A1c (HbA1c), and hormones before (week 0) and 3 and 12 weeks after anamorelin administration. The variables were evaluated at week 3 in 9 patients and at week 12 in 5 patients. At week 3, anamorelin administration resulted in body weight gain and increased the levels of growth hormone and HbA1c, as well as insulin-like growth factor-1 standard deviation scores (IGF-1 SD scores). At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone. ΔBody weight and ΔIGF-1 SD score correlated positively at week 12. These results suggest that TSH and free testosterone levels can be affected 3 weeks after anamorelin administration; however, those variables tend to return to a state of equilibrium, and anabolic effects of anamorelin appear in long-term (≥ 12 weeks) users.
Keywords anamorelin body weight cancer cachexia endocrine system
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-06
Volume volume77
Issue issue3
Publisher Okayama University Medical School
Start Page 235
End Page 241
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37357624
Web of Science KeyUT 001026279600001
FullText URL fulltext.pdf
Author Fujita, Kana| Otsuka, Yuki| Sunada, Naruhiko| Honda, Hiroyuki| Tokumasu, Kazuki| Nakano, Yasuhiro| Sakurada, Yasue| Obika, Mikako| Hagiya, Hideharu| Otsuka, Fumio|
Keywords COVID-19 aftercare clinic (CAC) headache quality of life (QOL) long COVID post COVID-19 condition (PCC)
Published Date 2023-05-18
Publication Title Journal of Clinical Medicine
Volume volume12
Issue issue10
Publisher MDPI
Start Page 3533
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 37240639
DOI 10.3390/jcm12103533
Web of Science KeyUT 000997859300001
Related Url isVersionOf https://doi.org/10.3390/jcm12103533
FullText URL fulltext20230512-02.pdf fig20230512-02.pdf
Author Yamamoto, Koichiro| Otsuka, Fumio|
Note © 2022 Mayo Foundation for Medical Education and Research. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.mayocp.2022.01.010.|
Published Date 2022-04
Publication Title Mayo Clinic Proceedings
Volume volume97
Issue issue4
Publisher Elsevier BV
Start Page 652
End Page 652
ISSN 0025-6196
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Mayo Foundation for Medical Education and Research
File Version author
PubMed ID 35379418
DOI 10.1016/j.mayocp.2022.01.010
Web of Science KeyUT 000795076500005
Related Url isVersionOf https://doi.org/10.1016/j.mayocp.2022.01.010