result 342 件
| JaLCDOI | 10.18926/AMO/65152 |
|---|---|
| FullText URL | 77_2_209.pdf |
| Author | Sakamoto, Masaki| Teraishi, Fuminori| Shigeyasu Kunitoshi| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| Abstract | A 70-year-old male with anal pain and fever was diagnosed with rectal cancer perforation and abscess in the right gluteus maximus (GM) muscle. He underwent a transverse colon colostomy followed by preoperative capecitabine+oxaliplatin. Some local control was achieved but a residual abscess was observed in the right GM muscle. To secure circumferential resection margin by tumor reduction, he received chemoradiotherapy as total neoadjuvant therapy (TNT) and underwent laparoscopic abdominoperineal resection, D3 lymph node dissection, combined coccyx resection, and partial resection of the right GM muscle. The skin defect and pelvic dead space were filled with a right lateral vastus lateral great muscle flap. Histopathologically, the resected specimen showed no tumor cells in the primary tumor or lymph nodes, indicating a pathological complete response (pCR). This case suggests that TNT might improve the R0 resection and pCR rates and overall survival. |
| Keywords | locally advanced rectal cancer total neoadjuvant therapy lateral vastus lateral great muscle flap |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-04 |
| Volume | volume77 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 209 |
| End Page | 213 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37094960 |
| Web of Science KeyUT | 000982563800003 |
| JaLCDOI | 10.18926/AMO/65144 |
|---|---|
| FullText URL | 77_2_147.pdf |
| Author | Arias, Zulema| Haines, Stephanie| Yamamoto, Tadashi| Hatanaka, Kazu| Yamashiro, Keisuke| Sonoi, Norihiro| Takashiba, Shogo| |
| Abstract | The curriculum at the Department of Pathophysiology in the Periodontal Sciences program at Okayama University includes normative preclinical training (NPT) using phantoms. NPT is given to the whole class of 5 th year students divided in groups of 8 students/instructor. In 2019, an innovative personalized preclinical training (PPT) pilot study was implemented for this group of students whereby two students, each with their own dental unit, were coached by one instructor. The main topics covered were dental ergonomics and endodontics. We aimed to evaluate the effectiveness of PPT in dental ergonomics and endodontics toward increasing the knowledge and future clinical skills of students who had already undergone NPT. A test on endodontics was taken before and after PPT. A questionnaire was completed to assess their perception of improvement regarding the above-mentioned topics. Test scores and questionnaire results both showed that the students’ level of knowledge and awareness of future clinical skills was significantly higher after PPT. This pilot study demonstrated that PPT increased the students’ knowledge and future clinical skills. As preclinical training forms the foundation for clinical practice, investment in future research regarding this personalized approach is likely to enhance students’ understanding and clinical performance. |
| Keywords | preclinical personalized education dental ergonomics endodontics clinical skills improvement undergraduate students |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-04 |
| Volume | volume77 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 147 |
| End Page | 159 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37094952 |
| Web of Science KeyUT | 000982503800004 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Mitoma, Tomohiro| Maki, Jota| Ooba, Hikaru| Eto, Eriko| Takahashi, Kasumi| Kondo, Tsunemasa| Ikeda, Tomohiro| Sakamoto, Yoko| Mitsuhashi, Toshiharu| Masuyama, Hisashi| |
| Keywords | Oestrogen replacement therapy Knee osteoarthritis Muscle resistance exercise Sarcopenia Physical performance |
| Published Date | 2023-02-18 |
| Publication Title | BMC Geriatrics |
| Volume | volume23 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 104 |
| ISSN | 1471-2318 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 36800940 |
| DOI | 10.1186/s12877-023-03828-y |
| Web of Science KeyUT | 000936860000001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12877-023-03828-y |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kawanishi, Shiho| Kojima, Keiichi| Shibukawa, Atsushi| Sakamoto, Masayuki| Sudo, Yuki| |
| Published Date | 2023-01-25 |
| Publication Title | ACS Omega |
| Volume | volume8 |
| Publisher | American Chemical Society |
| Start Page | 4826 |
| End Page | 4834 |
| ISSN | 2470-1343 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Authors. |
| File Version | publisher |
| PubMed ID | 36777568 |
| DOI | 10.1021/acsomega.2c06980 |
| Web of Science KeyUT | 000926216100001 |
| Related Url | isVersionOf https://doi.org/10.1021/acsomega.2c06980 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Katayama, Yukitoshi| Tsukada, Takehiro| Hyodo, Susumu| Sakamoto, Hirotaka| Sakamoto, Tatsuya| |
| Published Date | 2022-12-07 |
| Publication Title | Plos One |
| Volume | volume17 |
| Issue | issue12 |
| Publisher | Public Library Science |
| Start Page | e0277968 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Katayama et al. |
| File Version | publisher |
| PubMed ID | 36477197 |
| DOI | 10.1371/journal.pone.0277968 |
| Web of Science KeyUT | 000925063300030 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0277968 |
| JaLCDOI | 10.18926/AMO/64362 |
|---|---|
| FullText URL | 77_1_57.pdf |
| Author | Katsumata, Ryo| Manabe, Noriaki| Monobe, Yasumasa| Ayaki, Maki| Suehiro, Mitsuhiko| Fujita, Minoru| Kamada, Tomoari| Kawamoto, Hirofumi| Haruma, Ken| |
| Abstract | Melanosis coli (MC) is an acquired colorectal disorder visualized as colonic mucosa pigmentation. Disease severity is confirmed based on MC depth, shape, and coloration, although the clinical course is not fully understood. This study sought to clarify characteristics of MC development and disappearance and to investigate its clinical course and severity. Contributors to MC grade progression were explored. This study reviewed MC cases discovered via colonoscopy at a single institution over a 10-year period. Of all 216 MC cases, 17 developing and 10 disappearing cases were detected. Anthranoid laxative use was a key factor: 29.4% of the developing cases had used such agents before the initial MC diagnosis, whereas 40% of disappearing cases had discontinued anthranoids prior to detection of MC disappearance. Among 70 grade I cases, progression to grade II occurred in 16 cases during a mean follow-up of 3.67±2.1 years (rate of progression=22.8%). Males more commonly showed progressive than stable grade I cases, and the probability of progression was higher for male than for female cases. An association between anthranoid administration and MC presence was presumed, and grade I MC was found to progress in severity over 5 years. |
| Keywords | melanosis sex characteristics laxatives colorectal neoplasms colonoscopy |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-02 |
| Volume | volume77 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 57 |
| End Page | 64 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36849146 |
| Web of Science KeyUT | 000952992100003 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tokumasu, Kazuki| Nishimura, Yoshito| Sakamoto, Yoko| Obika, Mikako| Kataoka, Hitomi| Otsuka, Fumio| |
| Keywords | COVID-19 medical student medical education in-person communication online communication stress perception |
| Published Date | 2023-01-15 |
| Publication Title | International Journal of Environmental Research and Public Health |
| Volume | volume20 |
| Issue | issue2 |
| Publisher | MDPI |
| Start Page | 1579 |
| ISSN | 1660-4601 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36674333 |
| DOI | 10.3390/ijerph20021579 |
| Web of Science KeyUT | 000915112800001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijerph20021579 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Osinde, Cyprian| Sakamoto, Wataru| Kajiya-Kanegae, Hiromi| Sobhy, Islam S.| Tugume, Arthur K.| Nsubuga, Anthony M.| Galis, Ivan| |
| Keywords | Quantitative trait locus (QTL) stem borer herbivory BTx623 and NOG recombinant inbred lines (RILs) sorghum |
| Published Date | 2023-12-31 |
| Publication Title | Journal Of Plant Interactions |
| Volume | volume18 |
| Issue | issue1 |
| Publisher | Taylor & Francis Ltd |
| Start Page | 2153182 |
| ISSN | 1742-9145 |
| NCID | AA11980303 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Author(s). |
| File Version | publisher |
| DOI | 10.1080/17429145.2022.2153182 |
| Web of Science KeyUT | 000905581600001 |
| Related Url | isVersionOf https://doi.org/10.1080/17429145.2022.2153182 |
| Title Alternative | The beginning date of wet rice cultivation at the of Okayama University site: Tree ring oxygen isotope dating and radiocarbon 14 age of weirs from the mid-I stage of the Yayoi period |
|---|---|
| JaLCDOI | 10.18926/64199 |
| FullText URL | jdc_002_018.pdf |
| Author | FUJIO, Shinichiro| SAKAMOTO, Minoru| SANO, Masaki| |
| Abstract | This article clarifies the date when paddy field rice cultivation began at the archaeological site located within the Okayama University campus. The analysis used tree ring oxygen isotope dating and radiocarbon dating. When the oxygen isotope ratios of wood used in paddy weirs detected in the 23rd excavation season were examined, peaks could be seen in two places: in the 10th century BC and the 6th century BC. Since the weir was accompanied by mid-I stage Yayoi pottery, which was dated to the 6th century BC using radiocarbon dating, tree ring dating determined that the weir was made from wood cut down soon after 540 BC. Therefore, it was reaffirmed that one of the points of the mid-I stage can be dated to the middle of the 6th century BC. Next is the age of the early-I stage, when paddy field rice cultivation began on the Okayama Plain. In the Tsuruba area of the Nishikawazu archaeological site in Shimane Prefecture, where paddy field rice cultivation is thought to have begun at the same time as on the Okayama Plain, tree ring oxygen isotope dating of wood accompanied by early-I stage pottery has been reported. The date of 649 BC date means that one of the earliest stages of the early-I period dates to the middle of the 7th century BC. Therefore, we reaffirmed the view that paddy rice cultivation in the Chugoku region, such as Okayama and Shimane, began in the 7th century BC. It also became clear that the beginning of paddy field rice cultivation in the Chugoku region occurred at a time when the climate that had been the base of cold in the 10th century BC gradually warmed and the relatively humid climate began to turn to arid. |
| Keywords | 土器付着炭化物：carbides adhering to pottery 酸素同位体比年輪年代法：tree ring oxygen isotope dating 炭素14年代法：radiocarbon dating 岡山大学構内遺跡：the Okayama University site 弥生前期：the early Yayoi period 水田稲作：wet rice cultivation 堰：weirs |
| Amo Type | 研究ノート (Research note) |
| Publication Title | Dynamics of Civilizations |
| Published Date | 2023-03-25 |
| Volume | volume2 |
| Publisher | 岡山大学文明動態学研究所 |
| Start Page | 18 |
| End Page | 31 |
| ISSN | 2436-8326 |
| Content Type | Journal Article |
| language | Japanese |
| Copyright Holders | © 2023 by RIDC |
| File Version | publisher |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Daimon, Masahiro| Katsumura, Takafumi| Sakamoto, Hirotaka| Ansai, Satoshi| Takeuchi, Hideaki| |
| Published Date | 2022-11-16 |
| Publication Title | Scientific Reports |
| Volume | volume12 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 19665 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 36385126 |
| DOI | 10.1038/s41598-022-23871-w |
| Web of Science KeyUT | 000884825100096 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-022-23871-w |
| FullText URL | fulltext20221117-1.pdf |
|---|---|
| Author | Katayama, Yukitoshi| Miura, Ayane| Sakamoto, Tatsuya| Takanami, Keiko| Sakamoto, Hirotaka| |
| Keywords | itchy eyes histamine gastrin-releasing peptide receptor footedness |
| Published Date | 2022-10-19 |
| Publication Title | Proceedings of the Royal Society B: Biological Sciences |
| Volume | volume289 |
| Issue | issue1985 |
| Publisher | The Royal Society |
| Start Page | 20221126 |
| ISSN | 0962-8452 |
| NCID | AA00786976 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Author(s) |
| File Version | author |
| PubMed ID | 36259204 |
| DOI | 10.1098/rspb.2022.1126 |
| Web of Science KeyUT | 000872392900003 |
| Related Url | isVersionOf https://doi.org/10.1098/rspb.2022.1126 |
| JaLCDOI | 10.18926/AMO/64127 |
|---|---|
| FullText URL | 76_6_749.pdf |
| Author | Takami, Masanari| Yukawa, Yasutsugu| Noda, Yusuke| Yoshida, Munehito| Yamada, Hiroshi| |
| Abstract | We provide the first report of successful salvage surgery for a post-C1 laminectomy symptomatic recurrence of a retro-odontoid pseudotumor (ROP) that caused myelopathy. The 72-year-old Japanese woman presented with an ROP causing symptomatic cervical myelopathy. With ultrasonography support, we performed the enucleation of the ROP via a transdural approach and fusion surgery for the recurrence of the mass. At the final observation 2-year post-surgery, MRI demonstrated the mass’s regression and spinal cord decompression, and the patient’s symptoms had improved. Our strategy is an effective option for a symptomatic recurrence of ROP. |
| Keywords | recurrent retro-odontoid pseudotumor salvage surgery transdural resection C1 laminectomy ultra-sonography |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-12 |
| Volume | volume76 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 749 |
| End Page | 754 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36549779 |
| Web of Science KeyUT | 000905195100017 |
| JaLCDOI | 10.18926/AMO/64126 |
|---|---|
| FullText URL | 76_6_743.pdf |
| Author | Tanaka, Masato| Suthar, Hardik| Desai, Dhvanit| Yamauchi, Taro| Arataki, Shinya| Fujiwara, Yoshihiro| Uotani, Koji| Oda, Yoshiaki| Misawa, Haruo| |
| Abstract | We describe a floating technique via a posterolateral approach with intraoperative O-arm navigation to facilitate decompression of the spinal cord in thoracic myelopathy due to severe ossification of the posterior longitudinal ligament (OPLL). A 62-year-old man with myelopathy due to thoracic OPLL had left-leg muscle weakness, urinary disturbance, and spastic gait. Bilateral leg pain and gait disturbance had persisted for 2 years. He was successfully treated by the posterolateral OPLL floating procedure and posterior pedicle fixation under O-arm navigation. At a 2-year follow-up, manual muscle testing results and sensory function of the left leg had recovered fully. His cervical Japanese Orthopedic Association score had improved from 5/12 to 11/12. The novel intraoperative O-arm navigation-guided posterolateral floating procedure for thoracic OPLL is effective for achieving precise decompression and strong fixation with a posterior approach only and can provide an excellent result for severe thoracic OPLL without the risk of adverse events from intraoperative radiation. |
| Keywords | ossification of the posterior longitudinal ligament floating method navigation surgery C-arm free |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-12 |
| Volume | volume76 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 743 |
| End Page | 748 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36549778 |
| Web of Science KeyUT | 000905195100016 |
| JaLCDOI | 10.18926/AMO/64122 |
|---|---|
| FullText URL | 76_6_715.pdf |
| Author | Mohammed Zahedul Islam Nizami| Gorduysus, Melahat| Shinoda-Ito, Yuki| Yamamoto, Tadashi| Nishina, Yuta| Takashiba, Shogo| Arias, Zulema| |
| Abstract | The failure of endodontic treatment is directly associated with microbial infection in the root canal or periapical areas. An endodontic sealer that is both bactericidal and biocompatible is essential for the success of root canal treatments. This is one of the vital issues yet to be solved in clinical dental practice. This in vitro study assessed the effectiveness of graphene oxide (GO) composites GO-CaF2 and GO-Ag-CaF2 as endodontic sealer materials. Dentin slices were coated with either the GO-based composites or commonly used root canal sealers (non-eugenol zinc oxide sealer). The coated slices were treated in 0.9% NaCl, phosphate-buffered saline (PBS), and simulated body fluid (SBF) at 37˚C for 24 hours to compare their sealing effect on the dentin surface. In addition, the radiopacity of these composites was examined to assess whether they complied with the requirements of a sealer for good radiographic visualization. Scanning electron microscopy showed the significant sealing capability of the composites as coating materials. Radiographic images confirmed their radiopacity. Mineral deposition indicated their bioactivity, especially of GO-Ag-CaF2, and thus it is potential for regenerative application. They were both previously shown to be bactericidal to oral microbes and cytocompatible with host cells. With such a unique assemblage of critical properties, these GO-based composites show promise as endodontic sealers for protection against reinfection in root canal treatment and enhanced success in endodontic treatment overall. |
| Keywords | bioactive sealer graphene oxide mineral deposition antimicrobial activity radiopacity |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-12 |
| Volume | volume76 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 715 |
| End Page | 721 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36549774 |
| Web of Science KeyUT | 000905195100012 |
| JaLCDOI | 10.18926/AMO/64120 |
|---|---|
| FullText URL | 76_6_695.pdf |
| Author | Onishi, Hideki| Nouso, Kazuhiro| Takaki, Akinobu| Oyama, Atsushi| Adachi, Takuya| Wada, Nozomu| Takeuchi, Yasuto| Shiraha, Hidenori| Okada, Hiroyuki| |
| Abstract | This study sought to identify factors that are predictive of a therapeutic response to hepatic arterial infusion chemotherapy (HAIC) by focusing on the number of prior transcatheter arterial chemoembolization (TACE) sessions. To determine the parameters predicting a good response to HAIC, we retrospectively analyzed 170 patients with hepatocellular carcinoma (HCC) who received HAIC regimens comprising low-dose cisplatin combined with 5-fluorouracil (LFP) or cisplatin (CDDP) for the first time. In both the LFP and CDDP regimens, the response rates were significantly lower in patients with three or more prior TACE sessions than in those with two or fewer prior TACE sessions (LFP 57% versus 28%; p=0.01, CDDP 27% versus 6%; p=0.01). Multivariable logistic regression analysis revealed that the number of prior TACE sessions (≥ 3) was significantly associated with non-responder status (odds ratio 4.17, 95% Confidence Interval (CI) 1.76-9.86) in addition to the HAIC regimen. Multivariable analysis using the Cox proportional hazards model revealed that a larger number of prior TACE sessions (≥ 3) was a significant risk factor for survival (hazard ratio 1.60, 95% CI 1.12-2.29) in addition to Child-Pugh class, serum alpha-fetoprotein concentration, and maximum diameter of HCC. HCC patients who receive fewer prior TACE sessions (≤ 2) were found to be better responders to HAIC. |
| Keywords | hepatic arterial infusion chemotherapy hepatocellular carcinoma refractory transcatheter arterial chemoembolization |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-12 |
| Volume | volume76 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 695 |
| End Page | 703 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36549772 |
| Web of Science KeyUT | 000905195100010 |
| JaLCDOI | 10.18926/AMO/64118 |
|---|---|
| FullText URL | 76_6_679.pdf |
| Author | Asagi, Akinori| Sakaguchi, Chihiro| Nadano, Seijin| Nishina, Tomohiro| Hamamoto, Yasushi| Kataoka, Masaaki| Yamashita, Natsumi| Tanimizu, Masahito| Hyodo, Ichinosuke| |
| Abstract | Chemotherapy is insufficient to treat macroscopic vascular invasion (MVI) of hepatocellular carcinoma (HCC). We retrospectively investigated the treatment outcomes of patients who underwent three-dimensional conformal radiotherapy (3D-CRT) for HCC MVI and analyzed prognostic factors by multivariate analysis using a Cox proportional hazard model. Sixty-five patients were studied. MVI sites were the portal vein (n=48 patients), portal and hepatic veins (n=8), and hepatic vein (n=9). The median irradiation dose was 50 Gy. The median survival time (MST) was 7.5 months. Performance status 2 or 3, modified albumin-bilirubin grade 2b or 3, and massive/diffuse type were poor prognostic factors. Nineteen patients (29%) with a treatment effect of 3 or 4 (≥ 50% of tumor necrosis or regression) at the irradiation sites according to the Response Evaluation Criteria in Cancer of the Liver showed longer survival than those with an effect of 1 or 2 (MST 18.7 vs. 5.9 months, p<0.001). No treatment-related death occurred. The hepatic function reserve was preserved in more than 70% of patients. 3D-CRT controlled HCC MVI safely and was suggested to be a good treatment option. |
| Keywords | hepatocellular carcinoma macroscopic vascular invasion portal vein tumor thrombosis hepatic vein tumor thrombosis three-dimensional conformal radiotherapy |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-12 |
| Volume | volume76 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 679 |
| End Page | 688 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36549770 |
| Web of Science KeyUT | 000905195100008 |
| FullText URL | K0006684_abstract_review.pdf K0006684_fulltext.pdf K0006684_summary.pdf |
|---|---|
| Author | HASHIMOTO, Nozomu| |
| Published Date | 2022-09-22 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6684号 |
| Granted Date | 2022-09-22 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2022 Elsevier B.V. |
| JaLCDOI | 10.18926/AMO/64044 |
|---|---|
| FullText URL | 76_5_609.pdf |
| Author | Matsumoto, Ken| Fujishita, Keigo| Matsuda, Masayuki| Oka, Satoshi| Fujisawa, Yuka| Imai, Toshi| Machida, Takuya| |
| Abstract | A 69-year-old Japanese man with acute leukemia received post-transplant cyclophosphamide-based haploidentical stem cell transplantation (PTCY-haplo-SCT) but was readmitted with dyspnea and ground-glass-opacities of the lungs. Bronchoscopy showed inflammatory changes with no signs of infection. He received steroids but required intubation as his condition deteriorated. In addition to antithymocyte globulin and cyclophosphamide, we administered ruxolitinib but failed to save him. Autopsy findings revealed fibrotic nonspecific interstitial pneumonia (NSIP) without evidence of organizing pneumonia or infection. Thus, we diagnosed idiopathic pneumonia syndrome (IPS). As far as our knowledge, this is the first case of IPS with NSIP histology after PTCY-haplo-SCT. |
| Keywords | idiopathic pneumonia syndrome ruxolitinib post-transplant cyclophosphamide-based haploidentical stem cell transplantation nonspecific interstitial pneumonia |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-10 |
| Volume | volume76 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 609 |
| End Page | 615 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36352810 |
| Web of Science KeyUT | 000884907100016 |
| JaLCDOI | 10.18926/AMO/64040 |
|---|---|
| FullText URL | 76_5_585.pdf |
| Author | Choshi, Haruki| Watanabe, Mototsugu| Furukawa, Shinichi| Ujike, Hiroyuki| Kataoka, Kazuhiko| |
| Abstract | Pulmonary metastatic resection is a standard therapy for renal cell carcinoma (RCC). Although patients with pulmonary metastases who do not undergo any treatment have poor prognoses, it has been reported that resection for pulmonary metastases yields good clinical outcomes. We investigated the prognoses of the 10 Japanese patients (eight males, two females) who underwent a surgical resection of pulmonary metastasectomy from RCC at our institution between April 1, 2012 and March 31, 2020 and analyzed the prognostic factors. We determined the prognoses and calculated the 5-year overall survival (OS) and disease-free survival (DFS) rates. To identify prognostic factors, we compared the median DFS duration for each factor. Elderly patients (median age, 75.5 years) were more predominant compared to previous studies, and all 10 patients underwent a complete resection. The 5-year DFS rate was 30.5% (95%CI: 0.045-0.63) and the 5-year OS rate was 80% (95%CI: 0.20-0.97). The following factors were associated with better prognosis: female, disease-free interval≥36 months, and metastases size<12 mm. These results indicate that complete resection for pulmonary metastases from RCC resulted in good clinical outcomes, particularly for patients with better prognostic factors. |
| Keywords | renal cell carcinoma pulmonary metastasis complete resection |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-10 |
| Volume | volume76 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 585 |
| End Page | 591 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36352806 |
| Web of Science KeyUT | 000884907100012 |
| JaLCDOI | 10.18926/AMO/64031 |
|---|---|
| FullText URL | 76_5_511.pdf |
| Author | Tomita, Hayato| Kuramochi, Kenji| Fujikawa, Atsuko| Ikeda, Hirotaka| Komita, Midori| Kurihara, Yoshiko| Kobayashi, Yasuyuki| Mimura, Hidefumi| |
| Abstract | Iterative reconstruction (IR) improves image quality compared with filtered back projection (FBP). This study investigated the usefulness of model-based IR (forward-projected model-based iterative reconstruction solution [FIRST]) in comparison with FBP and hybrid IR (adaptive iterative dose reduction three-dimensional processing [AIDR 3D]) in low-dose paranasal CT. Twenty-four patients with paranasal sinusitis who underwent standard-dose CT (120 kV) and low-dose CT (100 kV) scanning before and after medical treatment were enrolled. Standard-dose CT scans were reconstructed with FBP (FBP120), and low-dose CT scans with FBP (FBP100), AIDR 3D, and FIRST. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in three anatomical structures and effective doses were compared using Mann–Whitney U test. Two radiologists independently evaluated the visibility of 16 anatomical structures, overall image quality, and artifacts. Effective doses in lowdose CT were significantly reduced compared with those in standard-dose CT (0.24 vs 0.43 mSv, p<0.001). FIRST achieved significantly higher SNR (p<0.01, respectively) and CNR (p<0.001, respectively) of evaluated structures and significant improvement in overall image quality (p<0.001), artifacts (p<0.001), and visibility related to muscles (p<0.05) compared to FBP120, FBP100, and AIDR 3D. FIRST allowed radiation-dose reduction, while maintaining objective and subjective image quality in low-dose paranasal CT. |
| Keywords | paranasal sinuses iterative reconstruction dose reduction low dose |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-10 |
| Volume | volume76 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 511 |
| End Page | 517 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36352797 |
| Web of Science KeyUT | 000884907100003 |
