result 308 件
| FullText URL | K0007020_abstract_review.pdf K0007020_summary.pdf |
|---|---|
| Author | SAKAMOTO, Kazuki| |
| Published Date | 2024-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第7020号 |
| Granted Date | 2024-03-25 |
| Thesis Type | Doctor of Philosophy in Dental Science |
| Grantor | 岡山大学 |
| language | Japanese |
| FullText URL | K0006998_abstract_review.pdf K0006998_fulltext.pdf |
|---|---|
| Author | TAKEZAKI, Daiki| |
| Published Date | 2024-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6998号 |
| Granted Date | 2024-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2023 Takezaki, Morizane, Ikeda, Iseki, Sakamoto, Kawakami, Hashiguchi, Shirakata, Nishina and Mukai. |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sakamoto, Hirotaka| Inutsuka, Ayumu| |
| Keywords | GFP with a palmitoylation signal (palGFP) plasmalemma localization neurosecretory vesicle immunoelectron microscopy oxytocin |
| Published Date | 2024-04-25 |
| Publication Title | ACTA HISTOCHEMICA ET CYTOCHEMICA |
| Volume | volume57 |
| Issue | issue2 |
| Publisher | The Japan Society of Histochemistry and Cytochemistry |
| Start Page | 85 |
| End Page | 88 |
| ISSN | 0044-5991 |
| NCID | AA00508022 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 The Japan Society of Histochemistry and Cytochemistry |
| File Version | publisher |
| PubMed ID | 38695035 |
| DOI | 10.1267/ahc.24-00001 |
| Web of Science KeyUT | 001223234800003 |
| Related Url | isVersionOf https://doi.org/10.1267/ahc.24-00001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sakamoto, Wataru| Takami, Tsuneaki| |
| Keywords | Biparental and maternal inheritance DPD1 (DEFECTIVE IN POLLEN ORGANELLE DNA DEGRADATION1) Nuclease Plastid inheritance Pollen |
| Published Date | 2023-09-13 |
| Publication Title | Plant and Cell Physiology |
| Volume | volume65 |
| Issue | issue4 |
| Publisher | Oxford University Press (OUP) |
| Start Page | 484 |
| End Page | 492 |
| ISSN | 0032-0781 |
| NCID | AA0077511X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 37702423 |
| DOI | 10.1093/pcp/pcad104 |
| Web of Science KeyUT | 001082402800001 |
| Related Url | isVersionOf https://doi.org/10.1093/pcp/pcad104 |
| JaLCDOI | 10.18926/AMO/66931 |
|---|---|
| FullText URL | 78_2_201.pdf |
| Author | Masunaga, Akari| Tabuchi, Motoyasu| Sakamoto, Shinya| Yoshimatsu, Rika| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro| |
| Abstract | Trousseau syndrome is characterized by cancer-associated systemic thrombosis. We describe the first case of a successfully treated gallbladder adenocarcinoma accompanied by Trousseau syndrome. A 66-year-old woman presented with right hemiplegia. Magnetic resonance imaging identified multiple cerebral infarctions. Her serum carbohydrate antigen 19-9 and D-dimer levels were markedly elevated, and a gallbladder tumor was detected via abdominal computed tomography. Venous ultrasonography of the lower limbs revealed a deep venous thrombus in the right peroneal vein. These findings suggested that the brain infarctions were likely caused by Trousseau syndrome associated with her gallbladder cancer. Radical resection of the gallbladder tumor was performed. The resected gallbladder was filled with mucus and was pathologically diagnosed as an adenocarcinoma. Her postoperative course was uneventful, and she received a one-year course of adjuvant therapy with oral S-1. No cancer recurrence or thrombosis was noted 26 months postoperatively. Despite concurrent Trousseau syndrome, a radical cure of the primary tumor and thrombosis could be achieved with the appropriate treatment. |
| Keywords | gallbladder cancer Trousseau syndrome radical surgery |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-04 |
| Volume | volume78 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 201 |
| End Page | 204 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38688839 |
| Web of Science KeyUT | 001227932200001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kanzaki, Yuki| Matoba, Ryo| Ishihara, Kenji| Morita, Tetsuro| Muraoka, Yuki| Kimura, Shuhei| Koto, Takashi| Kawasaki, Ryo| Baba, Takayuki| Okamoto, Fumiki| Inoue, Makoto| Sakamoto, Taiji| Tsujikawa, Akitaka| Morizane, Yuki| |
| Published Date | 2024-02-08 |
| Publication Title | PLoS ONE |
| Volume | volume19 |
| Issue | issue2 |
| Publisher | Public Library of Science |
| Start Page | e0297347 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 Kanzaki et al. |
| File Version | publisher |
| PubMed ID | 38329968 |
| DOI | 10.1371/journal.pone.0297347 |
| Web of Science KeyUT | 001164302700019 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0297347 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Wu, Chongyang| Tanaka, Ryota| Fujiyoshi, Kyohei| Akaji, Yasuaki| Hirobe, Muneto| Miki, Naoko| Li, Juan| Sakamoto, Keiji| Gao, Jian| |
| Keywords | bamboo sasa beech forest phenological gap canopy understory plant plant morphology plastically leaf phenology |
| Published Date | 2024-03-04 |
| Publication Title | Plants |
| Volume | volume13 |
| Issue | issue5 |
| Publisher | MDPI |
| Start Page | 719 |
| ISSN | 2223-7747 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 by the authors. |
| File Version | publisher |
| PubMed ID | 38475565 |
| DOI | 10.3390/plants13050719 |
| Web of Science KeyUT | 001183421800001 |
| Related Url | isVersionOf https://doi.org/10.3390/plants13050719 |
| JaLCDOI | 10.18926/AMO/66674 |
|---|---|
| FullText URL | 78_1_079.pdf |
| Author | Takahara, Masahiro| Hiraoka, Sakiko| Ohmori, Masayasu| Takeuchi, Keiko| Takei, Kensuke| Aoyama, Yuki| Yasutomi, Eriko| Igawa, Shoko| Inokuchi, Toshihiro| Toyosawa, Junki| Yamasaki, Yasushi| Kinugasa, Hideaki| Harada, Keita| Onishi, Hideki| Okada, Hiroyuki| |
| Abstract | This study examined the utility of the combined use of transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis the Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS and FIT were retrospectively enrolled. For TUS, the colon was divided into five segments, and the bowel wall thickness was measured and evaluated. The accuracy of FIT (> 100 ng/ml) in detecting mucosal inflammation (MES>0) was 0.93, whereas that of TUS (BWT>2 mm) in each segment was 0.84-0.97. The combined use of TUS and FIT may be helpful in noninvasive treatment strategies. |
| Keywords | transabdominal ultrasonography fecal immunochemical test ulcerative colitis Mayo endoscopic subscore |
| Amo Type | Short Communication |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-02 |
| Volume | volume78 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 79 |
| End Page | 83 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38419318 |
| Web of Science KeyUT | 001203658200004 |
| FullText URL | fulltext20240219-05.pdf |
|---|---|
| Author | Hashimoto, Masashi| Kuroda, Shinji| Kanaya, Nobuhiko| Kadowaki, Daisuke| Yoshida, Yusuke| Sakamoto, Masaki| Hamada, Yuki| Sugimoto, Ryoma| Yagi, Chiaki| Ohtani, Tomoko| Kumon, Kento| Kakiuchi, Yoshihiko| Yasui, Kazuya| Kikuchi, Satoru| Yoshida, Ryuichi| Tazawa, Hiroshi| Kagawa, Shunsuke| Yagi, Takahito| Urata, Yasuo| Fujiwara, Toshiyoshi| |
| Note | The version of record of this article, first published in British Journal of Cancer, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41416-024-02583-0| |
| Published Date | 2024-02-05 |
| Publication Title | British Journal of Cancer |
| Volume | volume130 |
| Issue | issue7 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 1187 |
| End Page | 1195 |
| ISSN | 0007-0920 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024 |
| File Version | publisher |
| PubMed ID | 38316993 |
| DOI | 10.1038/s41416-024-02583-0 |
| Web of Science KeyUT | 001156904400001 |
| Related Url | isVersionOf https://doi.org/10.1038/s41416-024-02583-0 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kato, Yusuke| Kuroda, Hiroshi| Ozawa, Shin-Ichiro| Saito, Keisuke| Dogra, Vivek| Scholz, Martin| Zhang, Guoxian| de Vitry, Catherine| Ishikita, Hiroshi| Kim, Chanhong| Hippler, Michael| Takahashi, Yuichiro| Sakamoto, Wataru| |
| Keywords | post-translational modification Arabidopsis thaliana protein degradation photosystem II photo-oxidative damage tryptophan oxidation Chlamydomonas reinhardtii |
| Published Date | 2023-11-21 |
| Publication Title | eLife |
| Volume | volume12 |
| Publisher | eLife Sciences Publications |
| Start Page | RP88822 |
| ISSN | 2050-084X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Kato, Kuroda, Ozawa et al. |
| File Version | publisher |
| PubMed ID | 37986577 |
| DOI | 10.7554/eLife.88822 |
| Web of Science KeyUT | 001134641800001 |
| Related Url | isVersionOf https://doi.org/10.7554/eLife.88822 |
| Author | Tada, Naoya| Uemori, Takeshi| Sakamoto, Junji| |
|---|---|
| Keywords | Mechanical engineering Microdevices made of thin metal sheet Pure titanium Deformation Microscopic characterization and microanalysis Plastic deformation Microscopic inhomogeneity and stress concentration Slip activity control |
| Note | © 2023 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Sep. 2025.| |
| Published Date | 2023-11 |
| Publication Title | Engineering Failure Analysis |
| Volume | volume153 |
| Publisher | Elsevier |
| Start Page | 107623 |
| ISSN | 1350-6307 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Elsevier Ltd. |
| File Version | author |
| DOI | 10.1016/j.engfailanal.2023.107623 |
| Web of Science KeyUT | 001148684500001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.engfailanal.2023.107623 |
| FullText URL | K0006921_abstract_review.pdf K0006921_fulltext.pdf |
|---|---|
| Author | KAWAI, Hiroki| |
| Published Date | 2023-09-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6921号 |
| Granted Date | 2023-09-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2023 by the authors. |
| FullText URL | fulltext20231114-03.pdf |
|---|---|
| Author | Matoba, Ryo| Morimoto, Noriko| Kawasaki, Ryo| Fujiwara, Miyuki| Kanenaga, Keisuke| Yamashita, Hidetoshi| Sakamoto, Taiji| Morizane, Yuki| |
| Keywords | Visual impairment Japan Certification criteria Survey Glaucoma |
| Note | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10384-023-00986-9| This fulltext file will be available in Apr. 2024.| |
| Published Date | 2023-04-17 |
| Publication Title | Japanese Journal of Ophthalmology |
| Volume | volume67 |
| Issue | issue3 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 346 |
| End Page | 352 |
| ISSN | 0021-5155 |
| NCID | AA00691177 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Japanese Ophthalmological Society 2023 |
| File Version | author |
| PubMed ID | 37067634 |
| DOI | 10.1007/s10384-023-00986-9 |
| Web of Science KeyUT | 000970743300001 |
| Related Url | isVersionOf https://doi.org/10.1007/s10384-023-00986-9 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ogawa, Yu| Iwano, Megumi| Shikanai, Toshiharu| Sakamoto, Wataru| |
| Keywords | FUZZY ONION LIKE (FZL) Arabidopsis chloroplast thylakoid thylakoid structure photosynthetic electron transfer |
| Published Date | 2023-09-28 |
| Publication Title | Frontiers in Plant Science |
| Volume | volume14 |
| Publisher | Frontiers Media |
| Start Page | 1279699 |
| ISSN | 1664-462X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Ogawa, Iwano, Shikanai and Sakamoto. |
| File Version | publisher |
| PubMed ID | 37841601 |
| DOI | 10.3389/fpls.2023.1279699 |
| Web of Science KeyUT | 001083954400001 |
| Related Url | isVersionOf https://doi.org/10.3389/fpls.2023.1279699 |
| JaLCDOI | 10.18926/AMO/65979 |
|---|---|
| FullText URL | 77_5_553.pdf |
| Author | Murokawa, Takahiro| Sakamoto, Shinya| Tabuchi, Motoyasu| Sui, Kenta| Ozaki, Kazuhide| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro| Yoshida, Hiroshi| |
| Abstract | Gastric cancer with peritoneal metastases is typically a devastating diagnosis. Ligamentum teres hepatis (LTH) metastasis is an extremely rare presentation with only four known cases. Herein, we report salvage surgery of successive metastases to the abdominal wall and LTH in a patient originally presenting with advanced gastric cancer with peritoneal metastasis, leading to long-term survival. A 72-year-old man with advanced gastric cancer underwent curative-intent distal gastrectomy with D2 lymph node dissection for gastric outlet obstruction. During this procedure, three small peritoneal metastases were detected in the lesser omentum, the small mesentery, and the mesocolon; however, intraoperative abdominal lavage cytology was negative. We added cytoreductive surgery for peritoneal metastasis. The pathological diagnosis of the gastric cancer was tubular adenocarcinoma with pT4aN1pM1(PER/P1b)CY0 stage IV (Japanese classification of gastric carcinoma/JCGC 15th), or T4N1M1b stage IV (UICC 7th). Post-operative adjuvant chemotherapy with S-1 (TS-1)+cisplatin (CDDP) was administered for 8 months followed by S-1 monotherapy for 4 months. At 28 months after the initial surgery, a follow-up computed tomography (CT) detected a small mass beneath the upper abdominal wall. The ass showed mild avidity on 18F-fluorodeoxyglucose positron-emission (FDG-PET) CT. Salvage resection was performed for diagnosis and treatment, and pathological findings were consistent with primary gastric cancer metastasis. At 49 months after the initial gastrectomy, a new lesion was detected in the LTH with a similar level of avidity on FDG-PET CT as the abdominal wall metastatic lesion. We performed a second salvage surgery for the LTH tumor, which also showed pathology of gastric cancer metastasis. There has been no recurrence up to 1 year after the LTH surgery. With multidisciplinary treatment the patient has survived almost 5 years after the initial gastrectomy. Curative-intent gastrectomy with cytoreductive surgery followed by adjuvant chemotherapy for advanced gastric cancer with localized peritoneal metastasis might have had a survival benefit in our patient. Successive salvage surgeries for oligometastatic lesions in the abdominal wall and the LTH also yielded favorable outcomes. |
| Keywords | gastric cancer peritoneal metastasis ligamentum teres hepatis oligometastasis salvage surgery |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-10 |
| Volume | volume77 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 553 |
| End Page | 559 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37899267 |
| Web of Science KeyUT | 001110832700001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamamoto, Hiromasa| Soh, Junichi| Okumura, Norihito| Suzuki, Hiroyuki| Nakata, Masao| Fujiwara, Toshiya| Gemba, Kenichi| Sano, Isao| Fujinaga, Takuji| Kataoka, Masafumi| Terazaki, Yasuhiro| Fujimoto, Nobukazu| Kataoka, Kazuhiko| Kosaka, Shinji| Yamashita, Motohiro| Inokawa, Hidetoshi| Inoue, Masaaki| Nakamura, Hiroshige| Yamashita, Yoshinori| Hotta, Katsuyuki| Yoshioka, Hiroshige| Morita, Satoshi| Matsuo, Keitaro| Sakamoto, Junichi| Date, Hiroshi| Toyooka, Shinichi| |
| Published Date | 2023-05-19 |
| Publication Title | PLoS ONE |
| Volume | volume18 |
| Issue | issue5 |
| Publisher | Public Library of Science |
| Start Page | e0285273 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Yamamoto et al. |
| File Version | publisher |
| PubMed ID | 37205678 |
| DOI | 10.1371/journal.pone.0285273 |
| Web of Science KeyUT | 001050599900034 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0285273 |
| Title Alternative | The 2022 Incentive Award of the Okayama Medical Association in Neuroscience (2022 Niimi Prize) |
|---|---|
| Author | Yada, Yuji| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2023-08-01 |
| Volume | volume135 |
| Issue | issue2 |
| Start Page | 61 |
| End Page | 62 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.135.61 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2023 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.135.61 |
| FullText URL | fulltext20230817-02.pdf |
|---|---|
| Author | Oti, Takumi| Sakamoto, Hirotaka| |
| Keywords | gastrin-releasing peptide male sexual function non-synaptic volume transmission oxytocin spinal cord |
| Note | This is the peer reviewed version of the following article: [Oti T, Sakamoto H. Neuropeptidergic control circuits in the spinal cord for male sexual behaviour: Oxytocin–gastrin-releasing peptide systems. J Neuroendocrinol. 2023; 35(9):e13324. doi:10.1111/jne.13324], which has been published in final form at [https://doi.org/10.1111/jne.13324]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in Jul. 2024.| |
| Published Date | 2023-07-16 |
| Publication Title | Journal of Neuroendocrinology |
| Volume | volume35 |
| Issue | issue9 |
| Publisher | Wiley |
| Start Page | e13324 |
| ISSN | 0953-8194 |
| NCID | AA10755083 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 British Society for Neuroendocrinology. |
| File Version | author |
| PubMed ID | 37515539 |
| DOI | 10.1111/jne.13324 |
| Web of Science KeyUT | 001036736100001 |
| Related Url | isVersionOf https://doi.org/10.1111/jne.13324 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Naito, Hiromichi| Sakuraya, Masaaki| Hongo, Takashi| Takada, Hiroaki| Yumoto, Tetsuya| Yorifuji, Takashi| Hifumi, Toru| Inoue, Akihiko| Sakamoto, Tetsuya| Kuroda, Yasuhiro| Nakao, Atsunori| SAVE-J II Study Group| |
| Keywords | Clinical decision-making Treatment limitation Futility Post-cardiac arrest syndrome ECPR |
| Note | The version of record of this article, first published in Critical Care, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13054-023-04534-2| |
| Published Date | 2023-06-27 |
| Publication Title | Critical Care |
| Volume | volume27 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 252 |
| ISSN | 1364-8535 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 37370155 |
| DOI | 10.1186/s13054-023-04534-2 |
| Web of Science KeyUT | 001022362000002 |
| Related Url | isVersionOf https://doi.org/10.1186/s13054-023-04534-2 |
| JaLCDOI | 10.18926/AMO/65495 |
|---|---|
| FullText URL | 77_3_301.pdf |
| Author | Kato, Takahide| Miyoshi, Seigo| Hamada, Chizuru| Sano, Yoshifumi| Nogami, Naoyuki| Yamaguchi, Osamu| Hamaguchi, Naohiko| |
| Abstract | Acute exacerbation (AE) of interstitial lung disease (ILD) is a severe complication of lung resection in lung cancer patients with ILD (LC-ILD). This study aimed to assess the predictive value of comorbidities other than ILD for postoperative AE in patients with LC-ILD. We retrospectively evaluated 68 patients with LC-ILD who had undergone lung resection. We classified them into two groups: those who had developed postoperative AE within 30 days after resection and those who had not. We analyzed patient characteristics, high-resolution computed tomography findings, clinical data, pulmonary function, and intraoperative data. The incidence of postoperative AEs was 11.8%. In univariate analysis, performance status (PS), honeycombing, forced vital capacity (FVC), and high hemoglobin A1c (HbA1c) levels without comorbidities were significantly associated with postoperative AE. Patients were divided into two groups according to cutoff levels of those four variables as determined by receiver operating characteristic curves, revealing that the rates of patients without postoperative AE differed significantly between groups. The present results suggested that preoperative comorbidities other than ILD were not risk factors for postoperative AE in patients with LC-ILD. However, a high preoperative HbA1c level, poor PS, low FVC, and honeycombing may be associated with postoperative AE of LC-ILD. |
| Keywords | lung cancer interstitial lung disease acute exacerbation comorbidity |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 301 |
| End Page | 309 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357631 |
| Web of Science KeyUT | 001026279600008 |
