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JaLCDOI 10.18926/40208
Title Alternative A Statistical and Clinical Study of Postoperative Intestinal Adhesions
FullText URL pitsr_030_040_045.pdf
Author Ohtani, Mitsuru|
Abstract The author studied 36 cases of postoperative intestinal adhesions treated in this insitute during the past ten years. The results obtained were as follow. 1) The sex ratio was 21 (male) to 15 (female). 2) Fifty-three percent of the cases ranged from 20 to 40 years in age. 3) The initial operations which supposedly caused the adhesions were appendectomies. 4) Of the primary causative disease of the acute intetinal obstruction group, appendicitis accounted for 62% and gastrointestinal diseases for 15.4%. The primary causative disease of the chronic intestinal obstruction group was found to be appendicitis in about 70% of the cases. 5) The chief complaints made by patients were of vomiting and generalized Severe pain of the abdomen. 6) The most frequent sites of occurrence of the adhesions were the greater omentum, the small intestine and the sutured part of the peritoneum. 7) As regards the final therapeutic approach, in the largest number of cases (36.% of the total) lysis of the adhesion was performed. In most other cases, however, distress was relieved by enterostomy, resection of the bowel, and so on. Finally, the four most recent cases, all of whom suffered from recurrent intestinal obstrution, were relieved of the major portion of their abdominal complaints by a new method, an improvement of the original technique advocated by Noble in 1937. The details of this new technique will be reported in the next issue.
Publication Title 岡山大学温泉研究所報告
Published Date 1962-04-25
Volume volume30
Start Page 40
End Page 45
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002401089
JaLCDOI 10.18926/40207
Title Alternative The Effect of a Single Bath in Radioactive Hot Spring Water on Portal Circulation Time
FullText URL 030_036_039.pdf
Author Nakahara, Yasuhiro|
Abstract Following Ueda-Yasuda's procedure, the author observed changes on the portal blood circulation time, the blood pressure and the pulse rate of five normal men following a bath in radioactive hot spring water. Measurements were taken three times: 30 minutes before the bath, immediately after the bath, and 30 minutes after the bath (the bath waS either 5 or 10 minutes in duration, and ranged in temperature from 41° to 43℃). Portal blood circulation time immediately after a 10 minute bath waS found to be significantly prolonged as compared with that taken 30 minutes before the bath. The changes in blood pressure and pulse rate observed after bathing were similar to those reported by other authors.
Publication Title 岡山大学温泉研究所報告
Published Date 1962-04-25
Volume volume30
Start Page 36
End Page 39
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40213
language Japanese
File Version publisher
NAID 40017532382
JaLCDOI 10.18926/40205
Title Alternative Balneological Studies of Kaike Hot Springs (I) Effect of the Internal Use of Kaike Spring Water on Gastric Acidity
FullText URL pitsr_030_014_019.pdf
Author Kawata, Yoshiro|
Abstract Kaike Hot Spring is situated at the seaside, in the western part of Tottori Prefecture, Japan. In chemical composition it contains 9.3 g. of salts per kilogram of spring water and may be classified as a common salt spring. The author examined the effect of the drinking of Kaike spring water on gastric acidity in 21 patients. a) Two hundred m!. of this spring water were given to 10 patients by stomach tube at 37℃. The gastric acidity of the patients was measured at 30-minute intervals for a period of 105 minutes following the administration of the spring water. In 3 cases of normal acidity and 6 cases of hyperacidiy, the spring water appeared to inhibit the secretion of gastric acid, compared with the effect of the caffein control water. b) Two hundred m!. of the spring water diluted two-fold with tap water were given to 11 patients. In two cases of normal acidity and two cases of hypoacidity, on significant difference was observed between the effects of the spring water and those of the control water. In all 7 cases of hyperacidity, however, the spring water observably depressed the acid secretion of the stomach, as compared with the effect of the control water. On the basis of these results, the author concludes that it is advisable to use the spring water diluted two-fold with tap water for the purpose of treating gastric disorders.
Publication Title 岡山大学温泉研究所報告
Published Date 1962-04-25
Volume volume30
Start Page 14
End Page 19
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002401087
JaLCDOI 10.18926/40204
Title Alternative Effect of Radioactive Hot Spring Baths on Leukocyte Functions (Wandering Velocity and Carbon-Particle Phagocytic Ability)
FullText URL 030_001_013.pdf
Author Inoue, Masakatsu|
Abstract The author studied the influence of a series of radioactive hot-spring baths, lasting 20 or 30 days, upon leukocyte functions in healthy male rabbits and in patients with rhenmatoid arthritis and other diseases. The radioactive hot springs used were "Hisui-no-Yu" and "Kenkyusho-sen" (the laboratory spring), both in Misasa Spa, the chemical compositions of which are deseribed in Table 1. The following results were obtained: 1) Wandering velocity of pseudo-neutrophilic leukocytes: When a series of plain water baths (41℃., for 5 minutes daily), were administered, velocity increased after the first bathing but later remained fairly constant, compared with initial levels, except for a temporary fall on the 9th day (Fig. 3). During the administration of a series of the weakly radioactive "Kenkyushosen" baths (43℃., for 5 minutes daily), it showed a slight increase during the first week, following a temporary fall after the first bathing, and a decrease during the third week, but it tended to return to the initial level by the forth week (Fig. 1). In the course of a series of the radioactive ·Hisui-no-Yu" baths (40℃., for 10 minutes daily), it increased during the first week and tended to decrease during the second week, but returned to the initial level by the third week (Fig. 2). 2) Phagocytic ability for carbon-particles of pseudo-neutrophic leukocytes in rabbits: When plain water baths were given, phagocytic ability showed a rise on the third day, after which it declined to the initial level and remained fairly constant to the end of the observation period (Fig. 6.). On the other hand, the phagocytic ability of the leukocytes in rabbits of the groups receiving radioactive hot-spring baths increased more and more markedly as serial bathing was continued, although it had slightly decreased immediately after the first bathing. The rise of phagocytic ability in the group bathed in "Kenkyusho-sen" was especially marked on the third and ninth days of serial bathing, and also on the tenth day after serial bathing had been discontinued (Fig. 4). This tendency was also observed in the group bathed in "Hisui-no-Yu", whose phagocytic ability was noticeable especially on the third and 14th days. The degree of the rise in phagocytic ability was demonstrably high in this group than in the former (Fig. 5). Acceleration of the phagocytic function of leukocytes in rabbits was observed up to the 40th day after the series of baths in the radioactive hot spring had been concluded. 3) From these findings. it is obvious that leukocyte function is increased by repeated bathing, but it should be kept in mind that a so-called dissociation phenomenon is present between the wandering velocity and the carbon-phagocytic ability of leukocytes in the groups bathed in hot springs: namely, wandering velocity showed a tendency to decline during the third week, while carbon particle phagocytic ability showed a marked increase during the same week. 4) In order to explore the effects of a series of radioactive hot-spring baths on leukocyte functions in patients with rheumatoid arthritis or other similar diseases (for example, back pain, fibrositis or neuritis), the author examined the wandering velocity and the phagocytic ability of neutrophils, and obtained the following results: The wandering velocity of neutrophils in patients with rheumatoid arthritis or similar diseases generally showed a tendency to increase during the adminlstration of a series of the radioactive "Kenkyusho-sen" baths at a temperature of 42~43℃. (Fig. 7). The carbon-particle phagocytic ability of neutrophils gradually increase from about the seventh day onward and reached a maximum during the second week, in patients with back pain, fibrositis and neuritis (Fig. 8a). In patients with rheumatoid arthritis, however, it declined temporarily on the fifth to seventh days in 3 out of 5 patients but thereafter increased gradually, reaching its maximum on the 20th day (Fig. 8b). Thus, the leukocyte functions in patients with rheumatoid arthritis are accelerated by serial bathing, but the response in some patients may be a decline of carbon-particle phagocytic ability during the first week. This is probably due to the stress bathing imposes on adrenocortical functions. It is believed, on the basis of the facts described above, that follow-up examinations of leucocyte functions can afford a better understanding of the effects of radioactive hot springs on the defence mechanisms operative in living bodies.
Publication Title 岡山大学温泉研究所報告
Published Date 1962-04-25
Volume volume30
Start Page 1
End Page 13
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40213
language Japanese
File Version publisher
NAID 40017532380
JaLCDOI 10.18926/40200
Title Alternative Epidemiological study of the prevalence of rheumatic disorders in rural districts in Tottori Prefecture, Japan
FullText URL 036_041_053.pdf
Author Esawa, Hidemitsu|
Abstract Epidemiological evaluation of rural population samples of Misasa, Tomari and Kofu villages in Tottori Prefecture, Japan (Fig. 1), for occurance of rheumatic disorders was performed. This region has an annual rainfall of about 80 inches. The principal occupations are farming, and fishery in part. 1. One thousand six hundreds and twenty-seven persons, age 30 and over were investigated by clinical and serological means. In this preliminary communication the prevalence of probable and definite rheumatoid arthritis, accoding to defined by the A.R.A. criteria, was 1.04% and low back pain-sciatic pain, arthralgia and painful shoulder (cervical spondylosis and so on) were 8.4, 8.9 and 7.1% respectively (Table 2 and 4). 2. Serum samples from residents in Misasa- and Tomari-districts were obtained and rheumatoid factor was tested by means of RA-test (Hyland Laboratories). The incidence of positive test was 3.2% in 407 males and 5.0% in 715 females, but there is no significant difference between the two. Concerning the effect of age, there was a general tendency for the proportion of positive test to be greatest in the older age groups (Fig. 2). 3. Serum uric acid concentrations of 230 males and 395 females were measured by the modified method of Folin-Wu (latron-kit-method). The mean serum uric acid concentration (with standard deviation) was found to be 4.02±0.18mg. per 100ml. for males and 3.38±0.13mg. per 100ml. for females (Fig. 3 and 4), and the differecne between the two was significant. The author found no gouty patient in this papulation survey.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 41
End Page 53
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532335
JaLCDOI 10.18926/40199
Title Alternative The determination of copper and zinc in W-1 by the atomic absorption flame photometry
FullText URL pitsr_036_037_040.pdf
Author Matsui, Yoshito| Banno, Shohei|
Abstract Copper and zinc in W-1 have been determined using a Jarrell-Ash Model 82-360 atomic absorption flame photometer. The results are 116 ± 3 ppm for Cu and 86 ± 3 ppm for Zn. (Errors are expressed by the probable error of the mean of four determinations.) These results compare favorably with the recently reported values, thereby suggesting that the background absorption effect is practically negligible in these concentration ranges. Net sample consumption was about 20 mg of W-1 powder per element.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 37
End Page 40
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400935
JaLCDOI 10.18926/40196
Title Alternative Lithium contents in the hot spring waters in western Japan
FullText URL pitsr_036_015_021.pdf
Author Henmi, Kitinosuke| Kusachi, Isao|
Abstract Sixty-five samples of mineral waters (mainly above 25℃) from western Japan were analyzed for their Li, Na, K, Mg, Ca, Al, Fe, and Cl contents. The determination of Li was carried out by argentimetric titration of LiCI after the removal of other components by the cation exchange chromatography. A significant correlation between Li and Na concentrations is demonstrated in most samples, in which the contamination of sea water is hardly conceivable. This strong correlation of Li and Na can plausibly be explained assuming that these components have dissolved into the ascending mineral waters from the country rocks having fairly uniform Li to Na ratios. In this connection it is noted that western Japan is characteristic of the vast outcrops of granodioritic or granitic rocks.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 15
End Page 21
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400932
JaLCDOI 10.18926/40194
Title Alternative Epidemiological research of radioactive springs (Misasa Hot Springs) on circulatory systems. II. Incidences of abnormal ECG findings and hypertension (A preliminary report)
FullText URL pitsr_036_001_005.pdf
Author Kitayama, Minoru| Matoba, Kunikazu|
Abstract Misasa Hot Springs water contains 4.81-1169.2×10(-10) curie per liter of radon and its temperature ranges from 53.0℃ to 76.0℃. The authors examined one group of 265 residents who are living over 1 year at Misasa Hot Springs and another control group of 226 residents at the middle district of Tottori Prefecture, where the Misasa area is singular for its high radon concentration. A living environment of these two groups is of same condition, for example, dietarily or economically. The incidences of abnormal ECG findings and hypertension in the both groups was analysed stochastically and the results obtained were as follows: 1. The incidences of abnormal ECG findings were found less in the residents at the radioactive hot springs area than another residents at the middle district of Tottori Prefecture. 2. The difference in these incidences were found especially about the ECG findings due to functional disorderes, for example, sinus tachycardia and bradycardia, premature supraventricural and ventricural systole, atrio-ventricural block and right bundle branch block. 3. The ECG findings due to organic disorderes, for example, both auricural and ventricural hypertrophy or strain, myocardial and coronary arterial lesions, auricural fibrillation and left bundle branch block, were not found different significantly between both groups. 4. No difference of the incidences of the functional and organic abnormal ECG findings between both aging groups, over 60 years old, were found. 5. The incidences of hypertension were not found different between both groups.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 1
End Page 5
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400931
JaLCDOI 10.18926/40189
Title Alternative Medical studies on the rural people (3). Incidence rate of hypertension in rural districts, Tottori Prefecture, Japan
FullText URL pitsr_037_037_042.pdf
Author Inoue, Masakatsu| Morinaga, Hiroshi|
Abstract The authors examined the blood pressure levels of 5, 358 out-patients of Branch Hospital of Okayama University Hospital, Tottori Prefecture, during the four-year period, from April, 1957 to March, 1961. The following results were obtained: I. The incidence of hypertension with a systolic blood pressure over 150 mmHg was 20.5% (1,093 cases of 5,358). 2. Patients with hypertension over 40 years of age was 35.9% in male and 41.5% in female. Females showed a higher incidence than males and the incidence rate of hypertension increased with age. 3. There was a tendency in the incidence rate of patients with hypertension decreased in summer and increased in cold seasons.
Publication Title 岡山大学温泉研究所報告
Published Date 1967-12-15
Volume volume37
Start Page 37
End Page 42
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400930
JaLCDOI 10.18926/40188
Title Alternative The isotopic ratio (234)U/(238)U of the ores and waters in Togo Mine, Tottori-ken, Japan
FullText URL pitsr_037_031_036.pdf
Author Umemoto, Shunji|
Abstract The ratio (234)U/(238)U of two groups of ores and the waters collected in Kannokura Deposit was determined by α-ray spectrometry. According to the geological and mineralogical observation, the ores of each group were formed in succession. Based on the assumption that (234)U/(238)U of the uranium in the leaching solution is higher than that in the ores, the obtained ratio supports the above mechanism of formation. Actually, the waters collected in Kannokura Deposit showed the fairly high value in (234)U/(238)U. Each stratum of a typical section of the mine was observed on the ratio, but the obtained values were in too much complicated relation to interpret.
Publication Title 岡山大学温泉研究所報告
Published Date 1967-12-15
Volume volume37
Start Page 31
End Page 36
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400929
JaLCDOI 10.18926/40187
Title Alternative The positive rate of RA- test in various diseases, with supplementary study on the RA-test of synovial fluid
FullText URL pitsr_037_021_030.pdf
Author Ezawa, Hidemitsu|
Abstract Since the report of the agglutination test with Streptococcus by Cecil in 1931 there appeared many reports dealing with the serum reaction involved in rheumatoid arthritis. Among these the modified form of sensitized sheep blood cell agglutination test as proposed by WAALER (1940) and ROSE (1948) had been for a long time the only method applied to the diagnosis of rheumatoid arthritis. However, as this method had disadvantages of its complex manipulation and of being relatively sensitive, generally satisfactory results could not be obtained with it. Since then the latex agglutination test by PLATZ and SINGER (1957) was used in conjuction with the bentonite agglutination test by BOZIEVICH (1957). By the RA-test it means the test where agglutination is attained by the combined reaction of the human serum to be tested and the polystyrene latex granules bound to human gamma-globulin, and it is being widely used in daily clinical examinations. For the purpose to know the positive rate of this test in disesaes other than rheumatoid arthritis, we applied this test to the patients with various diseases both visiting our out-patient clinic and those hospitalized, and studied the results.
Publication Title 岡山大学温泉研究所報告
Published Date 1967-12-15
Volume volume37
Start Page 21
End Page 30
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400928
JaLCDOI 10.18926/40186
Title Alternative Our experience in combined balneo- and chrysotherapy for rheumatoid arthritis
FullText URL pitsr_037_009_019.pdf
Author Ezawa, Hidemitsu|
Abstract There was a time when the adrenocortical hormones therapy was only available treatment for rheumatoid arthritis, but since it does not give lasting effect on chronic rheumatoid arthritis, opinions are varied as to its efficacy, so that at present we are still conducting studies about this problem. Ever since the reports on the gold therapy for rheumatoid arthritis of LANDE (1927) and FORESTIER (1929) the literature is replete with the results of gold therapy both in Europe and America. In Japan, however, it was with reports by OSHIMA (1957) and HASHIMOTO(1961) that first aroused the interest of general investigators in this gold therapy. Nevertheless, since we find no convincing methods of treatment, we attempted to give combined balneo- and chryotherapys therapy to the pateints coming to the Department of Internal Medicine of Misasa (Hot-springs) Hospital, which is located in Tottori Prefecture and is a Branch of Okayama University Hospital, over the period of the past five years, and studied the efficacy of such treatment. Our subjects were consisted of 93 cases of rheumatoid arthritis with duration of 4.8 years in average. For the balneotherapy the patients were made to rest for the first the bathing week, the combined with mud treatment and massage once or twice a day was given in the second week, and then the gold therapy was commenced. Gold thioglucose oil emulsion (Solganal B. product of Schering) was used. In the first week, 5-10 mg of Solganal B were given twice. 10 mg were given twice in the second week, and thereafter the doses were gradually increased until the total dosage reached 1.0~1.5g. By the combined balneo- and chrysotherapy applied to the 93 cases of rheumatoid arthritis, we obtained the results as follows. 1. The improvement in the erythrocyte sedimentation rate was observed in 77% of them. 2. The improvement in the CRP test was observed in 46%, but the aggravation was found in 8.7% of their conditions. 3. There were 53 cases (57%) whose RA-test was either weakened or turned negative. 4. Judging from the changes in the erythrocyte sedimentation rate and the doses of gold thioglucose given, the effects of such a treatment appear around the tenth week after the start of the treatment and it seems that the total dosage of 500 mg and over gold salt is most appropriate. 5. By the combined treatment there were 10 (48%) of 21 cases whose conditions had improved well enough as to withdraw corticosteroids treatment and remaining 11 cases (52%) who had improved to the extent where we could reduce the amount of corticosteroids. 6. By applying the evaluating system of HASHIMOTO, the efficacy rate of the treatment proves to be 89% in the cases given over 500 mg gold thioglucose, and out of these 49% showed a marked effect. Therefore, it seems that the optimal dosage is over 500 mg. 7. These results amply indicate that for the treatment of chronic rheumatoid arthritis the balneotherapy combined with some organic gold compound or salt (Solganal B in the present study) is highly beneficial.
Publication Title 岡山大学温泉研究所報告
Published Date 1967-12-15
Volume volume37
Start Page 9
End Page 19
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400927
JaLCDOI 10.18926/40181
Title Alternative The determination of serum triglycerides
FullText URL pitsr_038_077_084.pdf
Author Mifune, Masaaki|
Abstract Currently accepted methods for serum triglycerides, namely, the manual modified VAN HANDEL-KAWADE method and the semi-automated LOFLAND method, were critically examined. Since the absorbents, the quality of sulfuric acid, the processes of shaking, extraction, saponification, removal of ethanol after saponification, and the stability of colored solution appear to be essential factors governing precision and accuracy of the determination, the effects of these factors were studied. It was found that the process of removal of ethanol was most important. To obtain the reproducible absorption, it is most advantageous to evaporate off ethanol from the solution of pH⋍6 on an oil bath at 101℃. As a result of re-examination on LOFLAND'S semi-automated method using a standard AutoAnalyzer, it is shown that the mixing coils can be omitted, thereby making the analysis possible in 18 -19 minutes (In the original LOFLAND'S method it takes more than 22 minutes). In addition, this modification results in smaller amount of chromotropoc acid reagent necessary (2.9 ml/min. as compared to 5 ml/min. in the original method). The determination rate in this modified method is 25 samples per hour. The average values, standard deviations, and coefficients of variance for the same serum sample for ten analyses according to the suggested manual method were 55.0 mg/dl, 1.83 mg/dl, and 4.69%, respectively, and those according to the suggested semi-automated method were 53.6 mg/dl, 1.78mg/dl and 4.68%, respectively.
Publication Title 岡山大学温泉研究所報告
Published Date 1969-03-20
Volume volume38
Start Page 77
End Page 84
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398501
JaLCDOI 10.18926/40179
Title Alternative Study on effects of balneotherapy on blood pH, P(CO(2)) and P(O(2)) Part 3. The effects of balneotherapeutical procedures on blood pH, P(CO(2)) and P(O(2))
FullText URL 038_027_044.pdf
Author Yahata, Takaaki|
Abstract The effects of balneological procedures as well as the duration of hospitalization on blood pH, P(CO(2)) and P(O(2)) were studied in fifty-two patients chiefly including rheumatoid arthritics. The changes of these parameters in sixty minutes after any foment were discussed comparing with those in the control groups. The results were as follows. 1) Blood pH decreased in value from first to second hospital week and thereafter remained almost constant. No P(CO(2)) variation was observed. The P(O(2)) remained stable till third hospital week and then followed by up and down changes during the forth to the ninth week. 2) The arterial blood pH, P(CO(2)) and P(O(2)) in all showed a tendency to increase after the general spring bath of ten minutes duration (bath temp. : 40±1℃). The venous blood pH and P(O(2)) also increased as in the arterial but P(CO(2)) decreased. These non significcant changes in the venous blood were considered to be resulted from the increased cutaneous blood flow in the forearm. 3) It was showed that mud bath of twenty minutes duration (bath temp. : 40±1℃) made an influence on the venous blood pH, P(CO(2)) and P(O(2)) via two different mechanisms. The first is the increased blood flow which had five minute value of P(O(2)) and pH elevated but P(CO(2)) reduced significantly. The second is the prominent increase of oxygen uptake in which the significant reduction of five minute P(O(2)) value but no variation of pH or P(CO(2)) was demonstrated. It was suggested that these two types of variations were based on the difference of individual response to heat. 4) The signiilcant blood pH, P(CO(2)) and P(O(2)) changes after mud pack of twenty minutes duration (surface temp. : 40~50℃) were considered to reflect the increased blood flow. 5) The increased cutaneous blood flow induced by balneotherapeutical procedures was proved to remain as long as sixty minutes thereafter in almost all cases. 6) The blood pH, P(CO(2)) and P(O(2)) changes observed in the control groups were related mainly with the increased blood flow and only little, if any, with the elevated oxygen uptake.
Publication Title 岡山大学温泉研究所報告
Published Date 1969-03-20
Volume volume38
Start Page 27
End Page 44
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532344
JaLCDOI 10.18926/40173
Title Alternative Follow-up results of rheumatic disorders treated with hot springs
FullText URL pitsr_039_077_080.pdf
Author Matsumoto, Kinshi|
Abstract Misasa Spa, located in Tottori Prefecture, was discovered in 1164, and it has been widely used for the management of rheumatic disorders, gastrointestinal diseases and so on. In 1914, Dr. R. ISHIZU measured radon contents in Misasa spring waters to be 142.14 Mache, and then Misasa Hot Springs, alkaline common salt springs, were also known as radioactive hot springs. In July, 1958, patients with rheumatic complaints who had balneotherapy at Misasa Branch Hospital of Okayama University, from January, 1955 to March, 1958, were reexamined. A questionnaire about the effectiveness of balneotherapy was sent to 149 patients and 98 answers were received. The results were as follows: 1. Spa treatment was effective in 100% of shoulder-hand syndrome and osteo-arthrosis of the knee, in 95% of degenerative spondylosis, in 93% of rheumatoid arthritis, in 80% of low back pain, in 67% of sciatica, etc. Generally speaking, balneotherapy was effectual in 78 of 98 patients with rheumatic disorders (81.2%). 2. The effectiveness of spa treatment came out in the course of thermal cure in 74% of 78 cases, and the others recognized the effects after spa treatment was finished. 3. The effect of spa therapy on the subjective complaints was notable in the cases which had a period of spa treatment over half a month. In the cases which had a period of spa treatment within 2 weeks, it is thought that the period is too short to reveal the efficacy of hot spring bathing. 4. It appeared that drinking of hot spring water had no remarkable effect on rheumatic complaints. 5. Forty-three per cent of the cases answered that their body conditions during this inquiry time became better than that at the beginning of the balneotherapy, and the remainders of the reexamined cases were under the trcatments with cortisone, vitamine, massage, acupuncture and so forth.
Publication Title 岡山大学温泉研究所報告
Published Date 1970-03-30
Volume volume39
Start Page 77
End Page 80
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398498
JaLCDOI 10.18926/40172
Title Alternative The effect of radioaclive thermal bathing upon serum iron values
FullText URL 039_061_075.pdf
Author Yamamoto, Yasuhisa|
Abstract The author investigated the effect of radioactive hot spring bathing on serum iron values. The serum iron values were measured by Umemoto-Yamamoto's method using o-nitrosoresorcin monomethylether, as a colour-developing reagent. The chemical compositions of the spring water used is as following: pH : 7.04, Rn : 38-151x10(-10)curies/l, K(+) : 14.0, Na(+) : 540.2, Ca(++) : 61. 2, Mg(++) : 6.6, Fe(++) : 89.0, AI(+++) : 0.1, Cl(-) : 709.5, S0(4)(--) : 179.5, HCO(3)(-) : 226.7, H(2)SiO(3) : 89.0, HBO(2) : +, CO(2) : 29.5, totaling 1,827mg/kg. 1) Single bathing: The iron values in the serum were measured before and after 0, 1/2, 1 and 2 hours after the radioactive thermal bathing for 10 minutes in water of 41 ±2℃ in temperature. Single thermal bathing showed no significant effect on the serum iron values in healthy hnman subjects, but the serum iron concent:'ations in healthy white rabbits tended to decrease following single thermal bathing and to remain at a decreased level for 1/2 to 1 hour, and returned to normally within 2 hours from the time of the bathing (Table 1, 2 and Fig. 1, 2). 2) A series of baths: The author examined the serum iron values of patients with rheumatic disorders before and 3rd, 7th, 14th, 21st and 28th days after in the course of "a series of baths" in radioactive hot spring. Patients bathed in water of 41 ± 2℃ in temperature, for 5-10 minutes, 2 or 3 times daily. A fall in the serum iron values was seen on the 3rd to 7th days. At that time the pattern of iron absorption from intestine showed a iron dificiency anemia type. The rate of absorption of iron was rapid. At about the 14th day, the serum iron values of patients tended to increase but unbound iron-binding capacity of the serum decreased. Subsequently, the serum iron values returned to the initial levels between the 21st and 28th day (Table 3, 4, 5, and Fig. 3, 4, 5), 3) It is said that the reticulo-endothelial system plays an inportant part in iron metabolism. The author injected 5 ml of Indian ink into the aural vein of rabbits for the purpose of blocking the reticulo-endothelial system. These procedures were carried out once a day for 7 successive days. The rabbits with "a blockade of R. E. S." had no significant change in the serum iron values during a series of baths. From what has been stated in the above, it may be said that bathing in radioactive hot springs regubtes the iron metabolism of patients with anemia and brings about the acceleration of the medullary function.
Publication Title 岡山大学温泉研究所報告
Published Date 1970-03-30
Volume volume39
Start Page 61
End Page 75
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532352
JaLCDOI 10.18926/40170
Title Alternative Study on the conbined therapy of spa and gold salt in rheumatoid arthritis Part II. An experience of granulocytopenia possibly caused by gold salt preparation
FullText URL pitsr_039_037_042.pdf
Author Ikegami, Tadaoki| Yahata, Takaaki| Kitayama, Minoru| Morinaga, Hiroshi|
Abstract A thirty seven years old woman with rheumatoid arthritis was instituted gold salt intramuscularly twice a week on the nineteenth hospital day. On the fifty fourth day, however, it was discontinued at the total dosis of 180 mg because of the skin rush. In about ten days after stopping gold injection appeared high fever with shivering and granulocytopenia was demonstrated. With immediate administration of ACTH, adrenocortical hormons etc. including blood transfusion the abnormal findings of the blood pictures returned to normal and the patient became well. Recently, gold salts are so widely used in treatment of rheumatoid arthritis as one of specific antirheumatic agents that the possible severe side effect such as granulocytopenia, if quite rare, should always be considered in the course of gold therapy.
Publication Title 岡山大学温泉研究所報告
Published Date 1970-03-30
Volume volume39
Start Page 13
End Page 35
ISSN 0369-7142
language Japanese
File Version publisher
JaLCDOI 10.18926/40162
Title Alternative Isotopic study of Hot Springs in Japan, I Techniques for oxygen isotopic analysis of spring water
FullText URL pitsr_040_033_040.pdf
Author Matsubaya, Osamu| Sakai, Hitoshi| Tanaka, Hinako| Uemura, Tazue|
Abstract The CO(2)-H(2)O isotopic equilibration technique was studied for the routine analyses of the oxygen isotopic ratios of hot spring water. A reaction vessel containing 2 ml of water and 0.16 m mole of tank CO(2) was shaken for 18 hrs. in a constant-temperature bath at 25.0℃ (Figs. 1, 2, and 3), and the CO(2) was analyzed for the oxygen isotopic ratio by a MCKINNEY type mass spectrometer. Several aliquots of 1, 2 and 5 ml from a same water were each analyzed three times by successive equilibration (Table 1). The observed values differ depending on the volume of water but the corrected values by equation (6) indicate excellent agreement, implying the whole processes to be well controlled. The reproducibility of the isotopic analyses is better than ± 0.1‰ (Table 2) in most cases, and the accuracy would not be worse than ± 0.2‰ as demonstrated by the interlaboratory comparison of some standard samples (Table 3). Oxygen isotopic ratios of water from more than 70 hot springs in Japan are presented (Table 5). Although the results will be discussed in the following issues of this series of paper, most hot spring water have the δ(18)O values similar to those of meteoric waters in Japan. However, spring water from Arima Hot Springs, Hyogo-Pref., which has been known by its abnormally high chloride and low sulfate concentrations is of an exceptionally high δ(18)O value.
Publication Title 岡山大学温泉研究所報告
Published Date 1971-03-26
Volume volume40
Start Page 33
End Page 40
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398154
JaLCDOI 10.18926/40161
Title Alternative Studies on the uptake of (75)Se-selenomethionine by the pancreas Attempt to augment by the effects of protocols
FullText URL pitsr_040_019_031.pdf
Author Tokunou, Tsuneo|
Abstract Since the introduction of the pancreatic scanning using (75)Se-selenomethionine, there has been various protocols proposed to increase the pancreatic uptake of this isotope. In this experiment several protocols; as diets high carbohydrate meal, high protein meal, high fat meal, and as medicaments pancreozymin, secretin and phydroxyphenylsalicylamide (PHPS), were tested for determining the effects on the uptake of (75)Se-selenomethionine by the pancreas and the liver of the dog. The animals given protocols were sacrified at each of a number of selected times to compare P/L ratio on a percentper-gram concentration of (75)Se-selenomethionine and the total organ concentration of (75)Se-selenomethionine in the pancreas and in the liver. A controlled group of animals were fasted for 24-hour and sacrificed at each of same times. On P/L ratio basis it was found that animals with high carbohydrate meal had better ratio than those with no preparation during first 4-hour post administration. However, animals with each of high protein meal. fat meal and PI-IPS had lower ratio than those with no preparation. On the blood concentration, animals with each of high carbohydrate meal and secretin had lower variation of blood concentration than controlled group. Thus, from the results mentioned above, the protocol by high carbohydrate meal is proved to be useful in pancreatic scanning.
Publication Title 岡山大学温泉研究所報告
Published Date 1971-03-26
Volume volume40
Start Page 19
End Page 31
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398153
JaLCDOI 10.18926/40160
Title Alternative Clinical studies on electromyographic changes in rheumatoid arthritis Part III. Effect of radioactive hot spring baths
FullText URL pitsr_040_001_017.pdf
Author Ikegami, Tadaoki|
Abstract The author observed the changes in electromyographic patterns of 14 patients with rheumatoid arthritis (13 cases of classical rheumatoid arthritis and one case of definite rheumatoid arthritis) bathed 2 or 3 times daily in hot spring water at Misasa Spa, at a temperature of 40±1℃, 5-10 minutes. The electromyographic examination was performed on the biceps brachii, opponens pollicis and the abductor pollicis brevis. Intramuscular temperature was measured in the deltoid muscle. The results were as follows. 1) The intramuscular temperature in cases of rheumatoid arthritis did not deviate from normal subjects. 2) After the general spring bathing the intramuscular temperature increased about 1℃ and it had no difference between the patients with rheumatoid arthritis and normal subjects. 3) With increasing intramuscular temperature by the general spring bathing in cases of active rheumatoid arthritis the mean potential amplitude decreased and the mean potential duration increased. 4) With increasing intramuscular temperature by the general spring bathing in cases of inactive rheumatiod arthritis the mean amplitude increased and the mean duration decreased. 5) The patterns of potential duration and amplitude before and after a bath on re-examination, one month after a series of the general spring baths, showed a tendency of reverse of the initial patterns. 6) After two months of a series of the general spring baths, the patterns of electromyographic changes of patients with rheumatoid arthritis following the bathing were similar to the initial patterns.
Publication Title 岡山大学温泉研究所報告
Published Date 1971-03-26
Volume volume40
Start Page 1
End Page 17
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398152