result 940 件
| JaLCDOI | 10.18926/AMO/53562 |
|---|---|
| FullText URL | 69_4_255.pdf |
| Author | Miyahara, Hiroyuki| Maruyama, Hidehiko| Kanazawa, Akane| Iwasaki, Yuka| Shigemitsu, Yusuke| Watanabe, Hirokazu| Tokorodani, Chiho| Miyazawa, Mari| Nishiuchi, Ritsuo| Kikkawa, Kiyoshi| |
| Abstract | Since the introduction of the seven-valent pneumococcal conjugate vaccine (PCV7) in 2007, invasive pneumococcal disease has declined, but the incidence of Streptococcus pneumoniae serotype 19A has risen worldwide. The present study examined changes in the features of invasive pneumococcal disease since the introduction of the PCV7 in Kochi, Japan. Pediatric cases of invasive pneumococcal disease were investigated before and after vaccine introduction (January 2008 to December 2013). Cases of invasive pneumococcal disease tended to decrease after PCV7 introduction. In addition, before introduction of the vaccine, most serotypes causing invasive pneumococcal disease were those included in the vaccine. However, after the introduction, we found cases infected by serotypes not covered by vaccine. Penicillin-resistant S. pneumoniae was the predominant serotype causing invasive pneumococcal disease before introduction of the PCV7, and the susceptibility of this serotype to antibiotics improved after vaccine introduction. Serotype isolates identified after vaccine introduction were also relatively susceptible to antibiotic therapy, but decreased susceptibility is expected. |
| Keywords | seven-valent pneumococcal conjugate vaccine (PCV7) invasive pneumococcal disease (IPD) |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 255 |
| End Page | 260 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289917 |
| Web of Science KeyUT | 000365519100009 |
| Title Alternative | A prospective cohort study to define the clinical and pathological features of lung cancers harboring HER2 gene aberrations (the HER2-CS Study) and a phase II study of trastuzumab emtansine (recombinant) in patients with HER2-positive non-small cell lung cancer who recurred, progressed after standard chemotherapy, or were primarily refractory to standard chemotherapy |
|---|---|
| FullText URL | 127_127.pdf |
| Author | Kiura, Katsuyuki| Hotta, Katsuyuki| Sato, Akiko| Ohashi, Kadoaki| Ninomiya, Takashi| Minnami, Daisuke| Tabata, Masahiro| Kubo, Toshio| Kato, Yuka| Hirata, Taizo| |
| Keywords | 臨床研究中核病院 国立研究開発法人日本医療研究開発機構 文部科学省橋渡し研究加速ネットワークプログラム HER2-CS study trastuzumab emtansine |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-08-03 |
| Volume | volume127 |
| Issue | issue2 |
| Start Page | 127 |
| End Page | 132 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.127.127 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.127 |
| NAID | 130005096256 |
| Title Alternative | Successful laparoscopic resection of a cecal tumor in a 95-year-old man |
|---|---|
| FullText URL | 127_117.pdf |
| Author | Watanabe, Ayako| Inada, Ryo| Nagasaka, Takeshi| Yagi, Tomohiko| Matsumoto, Hijiri| Toshima, Toshiaki| Kikuchi, Satoru| Kuroda, Shinshi| Kondo, Yoshitaka| Mori, Yoshiko| Kishimoto, Hiroyuki| Fujiwara, Toshiyoshi| |
| Abstract | We report a successful laparoscopic resection of a cecal tumor in a 95-year-old Japanese man. The patient visited an initial hospital with a complaint of constipation in March 2014. Computed tomography scan and colonoscopy showed a stenotic ileocecal cancer with pericolic lymph node metastases, and he was referred to our department for management. Since his general condition was maintained, we performed a laparoscopic ileocecal resection with regional lymph node dissection for the patient. The operation achieved curative resection, and the tumor was diagnosed as a moderately differentiated adenocarcinoma and graded as pStage IIIa (pT3, pN0, pM0) according to the Japanese Classification of Colorectal Carcinoma, eighth edition. He was discharged on the 11th postoperative day without perioperative complications. Several large-scale randomized controlled trials （RCTs） revealed that laparoscopic surgeries for colorectal cancers have some advantages compared to open surgeries, including superior short-term outcomes and comparable long-term outcomes. Unfortunately, since these RCTs did not include enough elderly patients, the safety and feasibility of laparoscopic surgery for extremely elderly patients are still unknown. With respect to less-invasive procedures, these advantages of laparoscopic surgery are also thought to be the advantages for elderly colorectal cancer patients. |
| Keywords | 超高齢者（extremely elderly patient） 大腸癌（colorectal cancer） 腹腔鏡手術（laparoscopic surgery） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-08-03 |
| Volume | volume127 |
| Issue | issue2 |
| Start Page | 117 |
| End Page | 121 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.127.117 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.117 |
| NAID | 130005096253 |
| Title Alternative | The 2014 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2014 Sunada Prize) |
|---|---|
| FullText URL | 127_95.pdf |
| Author | Tokioka, Koji| |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-08-03 |
| Volume | volume127 |
| Issue | issue2 |
| Start Page | 95 |
| End Page | 97 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.127.95 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.95 |
| NAID | 130005096249 |
| Author | Watanabe, Yoshinari| |
|---|---|
| Published Date | 2014-03-31 |
| Publication Title | 岡山大学文学部プロジェクト研究報告書 |
| Volume | volume21 |
| Content Type | Research Paper |
| Author | Watanabe, Yoshinari| |
|---|---|
| Published Date | 2015-03-31 |
| Publication Title | 岡山大学文学部プロジェクト研究報告書 |
| Volume | volume22-2 |
| Content Type | Research Paper |
| Author | 鐸木 道剛| 渡邊 佳成| 遊佐 徹| |
|---|---|
| Published Date | 2015-03-31 |
| Publication Title | 岡山大学文学部プロジェクト研究報告書 |
| Volume | volume22-2 |
| Content Type | Others |
| FullText URL | K0005107 abstract_review.pdf K0005107_fulltext.pdf K0005107_fulltext_other1.pdf K0005107_fulltext_other2.pdf |
|---|---|
| Author | Watanabe, Mayu| |
| Published Date | 2015-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5107号 |
| Granted Date | 2015-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005075 abstract_review.pdf K0005075_fulltext.pdf |
|---|---|
| Author | Watanabe, Masako| |
| Published Date | 2015-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5075号 |
| Granted Date | 2015-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | O0004442_abstract_review.pdf O0004442_fulltext.pdf |
|---|---|
| Author | Watanabe, Masayuki| |
| Published Date | 2015-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 乙第4442号 |
| Granted Date | 2015-03-25 |
| Thesis Type | Doctor of Philosophy in Agriculture |
| Grantor | 岡山大学 |
| language | Japanese |
| JaLCDOI | 10.18926/AMO/53337 |
|---|---|
| FullText URL | 69_2_87.pdf |
| Author | Murayama, Hidehiko| Nakata, Yusei| Kanazawa, Akane| Watanabe, Hirokazu| Shigemitsu, Yusuke| Iwasaki, Yuka| Tokorodani, Chiho| Miyazawa, Mari| Nishiuchi, Ritsuo| Kikkawa, Kiyoshi| |
| Abstract | Ventriculoperitoneal shunts (VPSs) are used for the treatment of hydrocephalus. Here we analyzed the outcomes of VPS placements in 24 infants to determine the risk factors for shunt failure. The infants had undergone the initial VPS operation in our hospital between March 2005 and December 2013. They were observed until the end of January 2014. We obtained Kaplan-Meier curves and performed a multivariate Cox regression analysis of shunt failure. Of the 24 cases, the median (range) values for gestational age, birth weight, and birth head circumference (HC) were 37 (27-39) wks, 2,736 (686-3,788) g, and 35.3 (23.0-45.3) cm, respectively. The total number of shunt procedures was 45. Shunt failure rates were 0.51/shunt and 0.0053/shunt/year. Shunt infection rates were 0.13/shunt and 0.0014/shunt/year. The Kaplan-Meier analysis revealed an increased risk for shunt failure in infants ＜1 month old or in the HC ＞90ｵtile. The Cox regression analysis yielded hazard ratios (HRs) of 2.93 (95ｵ confidence interval (CI), 0.96-10.95, p＝0.059) for age ＜1 month, and 4.46 (95ｵCI:1.20-28.91,p＝0.023) for the HC ＞90ｵtile. The multivariate Cox regression analysis showed adjusted HRs of 17.56 (95ｵCI:2.69-202.8, p＝0.001) for age ＜1 month, and 2.95 (95ｵCI:0.52-24.84, p＝0.228) for the HC ＞90ｵtile. Our findings thus revealed that the risk factors for shunt failure in infants include age ＜1 month at the initial VPS placement. |
| Keywords | head circumference shunt failure shunt infection ventriculoperitoneal shunt |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-04 |
| Volume | volume69 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 87 |
| End Page | 93 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25899630 |
| Web of Science KeyUT | 000353181700003 |
| Title Alternative | Gene therapy using REIC/Dkk-3-encoding adenoviral vector for the treatment of malignant pleural mesothelioma |
|---|---|
| FullText URL | 127_47.pdf |
| Author | Toyooka, Shinichi| |
| Keywords | 悪性胸膜中皮腫 REIC/DKK-3 遺伝子治療 |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-04-01 |
| Volume | volume127 |
| Issue | issue1 |
| Start Page | 47 |
| End Page | 50 |
| ISSN | 0030-1558 |
| Related Url | http://www.okayama-u.ac.jp/user/oma/ |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.47 |
| NAID | 130005068349 |
| Title Alternative | The 2013 Incentive Award of the Okayama Medical Association in Neuroscience (2013 Niimi Prize) |
|---|---|
| FullText URL | 127_5.pdf |
| Author | Omote, Yoshio| |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-04-01 |
| Volume | volume127 |
| Issue | issue1 |
| Start Page | 5 |
| End Page | 8 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.5 |
| NAID | 130005068350 |
| JaLCDOI | 10.18926/CTED/53239 |
|---|---|
| Title Alternative | Study of developing a teaching program for a voter education from an elementary school to a high school Based on developing a tentative lesson plan of an elementary social studies in order to teach about vote |
| FullText URL | cted_005_093_100.pdf |
| Author | Kuwabara, Toshinori| Kudo, Bunzo| Tanahashi, Kenji| Yatabe, Reio| Koyama, Shigeki| Yoshimura, Kotaro| Oshihara, Susumu| Nagata, Tadamichi| Hashimoto, Yasuhiro| Watanabe, Tatsuya| |
| Abstract | 本研究は，市民社会に寄与し得る有権者の育成を目指し，児童・生徒の発達段階に応じた有権者教育のあり方 を追究して，小学校から高等学校までの12 年間を一貫する原理にもとづいた有権者教育プログラム開発のため の原理と方法を解明しようとするものである。そのために，第一に，子どもたちの政治に対する認識調査を行い， 子どもたちが政治的な概念についてどのような認識を持っており，それを教育によってどの程度まで変容させる ことができるかを明らかにした。そして，第二に，その調査の結果と従来の政治教育研究の成果をふまえて，有 権者教育のための小中高一貫カリキュラム・フレームワークを提示した。それに基づいて，第三に，具体的な単 元開発を行った。単元は，「選挙」，「議会」，「税金」という政治学の基本的概念をテーマとして取り上げて開発 したが，本稿では「選挙」概念をテーマとして開発した小学校社会科の単元を紹介する。 |
| Keywords | 有権者教育 小中高一貫 カリキュラム・フレームワーク 小学校社会科 単元開発 |
| Publication Title | 岡山大学教師教育開発センター紀要 |
| Published Date | 2015-03-06 |
| Volume | volume5 |
| Start Page | 93 |
| End Page | 100 |
| ISSN | 2186-1323 |
| language | Japanese |
| Copyright Holders | Copyright © 2015 岡山大学教師教育開発センター |
| File Version | publisher |
| NAID | 120005572545 |
| Author | Uchida, Daisuke| Shiraha, Hidenori| Kato, Hironari| Nagahara, Teruya| Iwamuro, Masaya| Kataoka, Junro| Horiguchi, Shigeru| Watanabe, Masami| Takaki, Akinobu| Nouso, Kazuhiro| Nasu, Yasutomo| Yagi, Takahito| Kumon, Hiromi| Yamamoto, Kazuhide| |
|---|---|
| Published Date | 2014-05 |
| Publication Title | Journal of Gastroenterology and Hepatology |
| Volume | volume29 |
| Issue | issue5 |
| Content Type | Journal Article |
| Title Alternative | The 2013 Incentive Award of the Okayama Medical Association in Cancer Research (2013 Hayashibara Prize and Yamada Prize) |
|---|---|
| FullText URL | 126_191.pdf |
| Author | Shien, Kazuhiko| |
| Abstract | 受賞対象論文: Shien K, Toyooka S, Yamamoto H, Soh J, Jida M, Thu KL, Hashida S, Maki Y, Ichihara E, Asano H, Tsukuda K, Takigawa N, Kiura K, Gazdar AF, Lam WL, Miyoshi S：Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells. Cancer Res (2013) 73, 3051-3061. |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-12-01 |
| Volume | volume126 |
| Issue | issue3 |
| Start Page | 191 |
| End Page | 194 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.191 |
| NAID | 130004903236 |
| Title Alternative | The 2013 Incentive Award of the Okayama Medical Association in General Medical Science (2013 Yuuki Prize) |
|---|---|
| FullText URL | 126_187.pdf |
| Author | Yamamoto, Hiromasa| |
| Abstract | 受賞対象論文: Yamamoto H, Higasa K, Sakaguchi M, Shien K, Soh J, Ichimura K, Furukawa M, Hashida S, Tsukuda K, Takigawa N, Matsuo K, Kiura K, Miyoshi S, Matsuda F, Toyooka S：Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas. J Natl Cancer Inst (2014) 106, djt338 |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-12-01 |
| Volume | volume126 |
| Issue | issue3 |
| Start Page | 187 |
| End Page | 190 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.187 |
| NAID | 130004903235 |
| Author | Kurahashi, Hiroaki| Watanabe, Masami| Sugimoto, Morito| Ariyoshi, Yuichi| Mahmood, Sabina| Araki, Motoo| Ishii, Kazushi| Nasu, Yasutomo| Nagai, Atsushi| Kumon, Hiromi| |
|---|---|
| Published Date | 2013-12 |
| Publication Title | Endocrine Journal |
| Volume | volume60 |
| Issue | issue12 |
| Content Type | Journal Article |
| Author | Takahara, Masahiro| Nemoto, Yasuhiro| Oshima, Shigeru| Matsuzawa, Yu| Kanai, Takanori| Okamoto, Ryuichi| Tsuchiya, Kiichiro| Nakamura, Tetsuya| Yamamoto, Kazuhide| Watanabe, Mamoru| |
|---|---|
| Published Date | 2013-12 |
| Publication Title | Immunology Letters |
| Volume | volume156 |
| Issue | issue1-2 |
| Content Type | Journal Article |
| Title Alternative | Induction therapy followed by surgery for non small-cell lung cancer |
|---|---|
| FullText URL | 126_103.pdf |
| Author | Toyooka, Shinichi| |
| Keywords | 非小細胞肺癌 導入療法 放射線化学療法 外科切除 |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-08-01 |
| Volume | volume126 |
| Issue | issue2 |
| Start Page | 103 |
| End Page | 107 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.103 |
| NAID | 130004685260 |
