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JaLCDOI 10.18926/40200
Title Alternative Epidemiological study of the prevalence of rheumatic disorders in rural districts in Tottori Prefecture, Japan
FullText URL 036_041_053.pdf
Author Esawa, Hidemitsu|
Abstract Epidemiological evaluation of rural population samples of Misasa, Tomari and Kofu villages in Tottori Prefecture, Japan (Fig. 1), for occurance of rheumatic disorders was performed. This region has an annual rainfall of about 80 inches. The principal occupations are farming, and fishery in part. 1. One thousand six hundreds and twenty-seven persons, age 30 and over were investigated by clinical and serological means. In this preliminary communication the prevalence of probable and definite rheumatoid arthritis, accoding to defined by the A.R.A. criteria, was 1.04% and low back pain-sciatic pain, arthralgia and painful shoulder (cervical spondylosis and so on) were 8.4, 8.9 and 7.1% respectively (Table 2 and 4). 2. Serum samples from residents in Misasa- and Tomari-districts were obtained and rheumatoid factor was tested by means of RA-test (Hyland Laboratories). The incidence of positive test was 3.2% in 407 males and 5.0% in 715 females, but there is no significant difference between the two. Concerning the effect of age, there was a general tendency for the proportion of positive test to be greatest in the older age groups (Fig. 2). 3. Serum uric acid concentrations of 230 males and 395 females were measured by the modified method of Folin-Wu (latron-kit-method). The mean serum uric acid concentration (with standard deviation) was found to be 4.02±0.18mg. per 100ml. for males and 3.38±0.13mg. per 100ml. for females (Fig. 3 and 4), and the differecne between the two was significant. The author found no gouty patient in this papulation survey.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 41
End Page 53
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532335
JaLCDOI 10.18926/40199
Title Alternative The determination of copper and zinc in W-1 by the atomic absorption flame photometry
FullText URL pitsr_036_037_040.pdf
Author Matsui, Yoshito| Banno, Shohei|
Abstract Copper and zinc in W-1 have been determined using a Jarrell-Ash Model 82-360 atomic absorption flame photometer. The results are 116 ± 3 ppm for Cu and 86 ± 3 ppm for Zn. (Errors are expressed by the probable error of the mean of four determinations.) These results compare favorably with the recently reported values, thereby suggesting that the background absorption effect is practically negligible in these concentration ranges. Net sample consumption was about 20 mg of W-1 powder per element.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 37
End Page 40
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400935
JaLCDOI 10.18926/40198
Title Alternative On climatology in Misasa Spa - Summary for past ten years
FullText URL pitsr_036_031_036.pdf
Author Matoba, Kunikazu| Yahata, Takaaki| Esawa, Hidemitsu| Inoue, Taeko|
Abstract Misasa Spa is well known as the most radioactive hot springs in Japan (maximum Rn content: 2330×10(-10) curie/l) and it has been applied to the management of neuralgia, rheumatic diseases, gastrointestinal disorders, etc. In this paper the climatological factors in Misasa Spa during the last decade (1956~1965) are summarized. The main features are as following: 1. The atmospheric temperature attains highest above 30℃ during the last ten days in July and the first ten days in August. In winter the temperature goes down below 0℃. during the last ten days in January and the first ten days in February. Owing to the high humidity, however, it is not felt so cold. 2. The amount of precipitation is more than 2,000 mm or so through the year. 3. The westwards wind is prevailing. The wind grade of 2~3 are observed most frequently. 4. Approximately 150 days of the year are clear fairly clear. 5. It is proved unexpectedly that it is rich in or the ultraviolet radiation even in winter. The results pointed above may suggest that the therapeutical period is optimal between March and October.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 31
End Page 36
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400934
JaLCDOI 10.18926/40197
Title Alternative Minor elements of the Nanbu Kotai of Nakatsugo Deposits, Ningyo Toge Uranium Mine
FullText URL pitsr_036_023_030.pdf
Author Watanabe, Koji|
Abstract The Nakatsugo Deposits are the main deposits of the Ningyo Toge Mine which is located in the northern part of Okayama Prefecture. Nakatsugo Deposits consists of the two main ore body, namely, Nanbu Kotai (southern ore body) and Hon Kotai (main ore body). Nanbu Kotai is occupied mostly by the unoxidized zone and high grade ores containing ningyoite (n% U) are widely found in the basal conglomerates. Minor elements in the common rocks such as basal granites, conglomerates, sandstones, dikes, and shales as well as the uraniferous ores were determined quantatively by fluorescent X-ray spectrometric analysis (for U, Zr, Y, Sr, As, and Fe) and spectrophotometric analysis (for Ni and Co). As the results of this study, it is found that the uraniferous ores are characterised by extremely high contents of Zr, Y, Sr, and As, which show positive and linear correlation with the U contents. It is confirmed that As is concentrated in pyrite which is usually associated with the uraniferous ores. Elements such as Ni and Co are slightly concentrated both in the uraniferous ores and andesite dikes. This fact may suggest some genetic relationship among them. However, it does not seem to be plausible to draw any definite conclusion on the origin of the uranium deposits from these relationships. As to the minor element distribution in common rocks, no systematic variation was found except for the rock samples closely associated with the ore deposits.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 23
End Page 30
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400933
JaLCDOI 10.18926/40196
Title Alternative Lithium contents in the hot spring waters in western Japan
FullText URL pitsr_036_015_021.pdf
Author Henmi, Kitinosuke| Kusachi, Isao|
Abstract Sixty-five samples of mineral waters (mainly above 25℃) from western Japan were analyzed for their Li, Na, K, Mg, Ca, Al, Fe, and Cl contents. The determination of Li was carried out by argentimetric titration of LiCI after the removal of other components by the cation exchange chromatography. A significant correlation between Li and Na concentrations is demonstrated in most samples, in which the contamination of sea water is hardly conceivable. This strong correlation of Li and Na can plausibly be explained assuming that these components have dissolved into the ascending mineral waters from the country rocks having fairly uniform Li to Na ratios. In this connection it is noted that western Japan is characteristic of the vast outcrops of granodioritic or granitic rocks.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 15
End Page 21
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400932
JaLCDOI 10.18926/40195
Title Alternative Clinical observations of gout
FullText URL 036_007_013.pdf
Author Yahata, Takaaki| Matoba, Kunikazu| Takenobu, Hisae|
Abstract Thirteen cases of gout encountered between April 1961 and December 1965 in the clinic of Branch Hospital of Okayama University at Misasa Spa are described and the brief outline of the treatment of gout is suggested. Clinical findings: 1) All of thirteen cases were male. 2) The presumptive onset of the disease showed the highest incidence at the fifth decade. 3) The period between the onset of gouty attack and the diagnosis of gout ranged from four months to twenty-seven years. 4) The first attack was experienced on the first metatarsophalangeal joint in six cases. 5) The gouty tophi in six and the urate crystals in seven cases were observed. Laboratory findings: 1) The high blood uric acid level was observed in all cases. 2) Seven of nine procedured had anemia with color index of normochrome in five, hyperchrome in two and hypochrome in one. 3) The white blood corpuscles remained within normal limit except of two cases of mild leucopenia. 4) Abnormal results of the liver function test were observed in BSP, C.C.F., TAKATA'S reaction and the serum transaminases (SGOT, SGPT). The normal serum protein was detected. 5) None of cases showed the positive RA test. CRP remained normal in the intermittent phase. Diagnosis: The differential diagnosis between gouty arthritis and rheumatoid arthritis was emphasized. Complications: 1) Renal calculi were recognized roentgenologically in two cases, who had experienced attacks of renal colic. 2) Renal function test showed abnormality in PSP excretion and urine concentration. Blood urea nitrogen increased above the normal limit in seven cases. The decreased urea clearance in two and decreased uric acid clearance in one of them were observed 3) Hypertention was seen in seven cases but all except one recovered normal values with treatment of gout plus hypertention.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 7
End Page 13
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532330
JaLCDOI 10.18926/40194
Title Alternative Epidemiological research of radioactive springs (Misasa Hot Springs) on circulatory systems. II. Incidences of abnormal ECG findings and hypertension (A preliminary report)
FullText URL pitsr_036_001_005.pdf
Author Kitayama, Minoru| Matoba, Kunikazu|
Abstract Misasa Hot Springs water contains 4.81-1169.2×10(-10) curie per liter of radon and its temperature ranges from 53.0℃ to 76.0℃. The authors examined one group of 265 residents who are living over 1 year at Misasa Hot Springs and another control group of 226 residents at the middle district of Tottori Prefecture, where the Misasa area is singular for its high radon concentration. A living environment of these two groups is of same condition, for example, dietarily or economically. The incidences of abnormal ECG findings and hypertension in the both groups was analysed stochastically and the results obtained were as follows: 1. The incidences of abnormal ECG findings were found less in the residents at the radioactive hot springs area than another residents at the middle district of Tottori Prefecture. 2. The difference in these incidences were found especially about the ECG findings due to functional disorderes, for example, sinus tachycardia and bradycardia, premature supraventricural and ventricural systole, atrio-ventricural block and right bundle branch block. 3. The ECG findings due to organic disorderes, for example, both auricural and ventricural hypertrophy or strain, myocardial and coronary arterial lesions, auricural fibrillation and left bundle branch block, were not found different significantly between both groups. 4. No difference of the incidences of the functional and organic abnormal ECG findings between both aging groups, over 60 years old, were found. 5. The incidences of hypertension were not found different between both groups.
Publication Title 岡山大学温泉研究所報告
Published Date 1966-10-25
Volume volume36
Start Page 1
End Page 5
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400931
Author 岡山大学温泉研究所|
Published Date 1966-10-25
Publication Title 岡山大学温泉研究所報告
Volume volume36
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1966-10-25
Publication Title 岡山大学温泉研究所報告
Volume volume36
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1967-12-15
Publication Title 岡山大学温泉研究所報告
Volume volume37
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1967-12-15
Publication Title 岡山大学温泉研究所報告
Volume volume37
Content Type Others
JaLCDOI 10.18926/40189
Title Alternative Medical studies on the rural people (3). Incidence rate of hypertension in rural districts, Tottori Prefecture, Japan
FullText URL pitsr_037_037_042.pdf
Author Inoue, Masakatsu| Morinaga, Hiroshi|
Abstract The authors examined the blood pressure levels of 5, 358 out-patients of Branch Hospital of Okayama University Hospital, Tottori Prefecture, during the four-year period, from April, 1957 to March, 1961. The following results were obtained: I. The incidence of hypertension with a systolic blood pressure over 150 mmHg was 20.5% (1,093 cases of 5,358). 2. Patients with hypertension over 40 years of age was 35.9% in male and 41.5% in female. Females showed a higher incidence than males and the incidence rate of hypertension increased with age. 3. There was a tendency in the incidence rate of patients with hypertension decreased in summer and increased in cold seasons.
Publication Title 岡山大学温泉研究所報告
Published Date 1967-12-15
Volume volume37
Start Page 37
End Page 42
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400930
JaLCDOI 10.18926/40188
Title Alternative The isotopic ratio (234)U/(238)U of the ores and waters in Togo Mine, Tottori-ken, Japan
FullText URL pitsr_037_031_036.pdf
Author Umemoto, Shunji|
Abstract The ratio (234)U/(238)U of two groups of ores and the waters collected in Kannokura Deposit was determined by α-ray spectrometry. According to the geological and mineralogical observation, the ores of each group were formed in succession. Based on the assumption that (234)U/(238)U of the uranium in the leaching solution is higher than that in the ores, the obtained ratio supports the above mechanism of formation. Actually, the waters collected in Kannokura Deposit showed the fairly high value in (234)U/(238)U. Each stratum of a typical section of the mine was observed on the ratio, but the obtained values were in too much complicated relation to interpret.
Publication Title 岡山大学温泉研究所報告
Published Date 1967-12-15
Volume volume37
Start Page 31
End Page 36
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400929
JaLCDOI 10.18926/40187
Title Alternative The positive rate of RA- test in various diseases, with supplementary study on the RA-test of synovial fluid
FullText URL pitsr_037_021_030.pdf
Author Ezawa, Hidemitsu|
Abstract Since the report of the agglutination test with Streptococcus by Cecil in 1931 there appeared many reports dealing with the serum reaction involved in rheumatoid arthritis. Among these the modified form of sensitized sheep blood cell agglutination test as proposed by WAALER (1940) and ROSE (1948) had been for a long time the only method applied to the diagnosis of rheumatoid arthritis. However, as this method had disadvantages of its complex manipulation and of being relatively sensitive, generally satisfactory results could not be obtained with it. Since then the latex agglutination test by PLATZ and SINGER (1957) was used in conjuction with the bentonite agglutination test by BOZIEVICH (1957). By the RA-test it means the test where agglutination is attained by the combined reaction of the human serum to be tested and the polystyrene latex granules bound to human gamma-globulin, and it is being widely used in daily clinical examinations. For the purpose to know the positive rate of this test in disesaes other than rheumatoid arthritis, we applied this test to the patients with various diseases both visiting our out-patient clinic and those hospitalized, and studied the results.
Publication Title 岡山大学温泉研究所報告
Published Date 1967-12-15
Volume volume37
Start Page 21
End Page 30
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400928
JaLCDOI 10.18926/40186
Title Alternative Our experience in combined balneo- and chrysotherapy for rheumatoid arthritis
FullText URL pitsr_037_009_019.pdf
Author Ezawa, Hidemitsu|
Abstract There was a time when the adrenocortical hormones therapy was only available treatment for rheumatoid arthritis, but since it does not give lasting effect on chronic rheumatoid arthritis, opinions are varied as to its efficacy, so that at present we are still conducting studies about this problem. Ever since the reports on the gold therapy for rheumatoid arthritis of LANDE (1927) and FORESTIER (1929) the literature is replete with the results of gold therapy both in Europe and America. In Japan, however, it was with reports by OSHIMA (1957) and HASHIMOTO(1961) that first aroused the interest of general investigators in this gold therapy. Nevertheless, since we find no convincing methods of treatment, we attempted to give combined balneo- and chryotherapys therapy to the pateints coming to the Department of Internal Medicine of Misasa (Hot-springs) Hospital, which is located in Tottori Prefecture and is a Branch of Okayama University Hospital, over the period of the past five years, and studied the efficacy of such treatment. Our subjects were consisted of 93 cases of rheumatoid arthritis with duration of 4.8 years in average. For the balneotherapy the patients were made to rest for the first the bathing week, the combined with mud treatment and massage once or twice a day was given in the second week, and then the gold therapy was commenced. Gold thioglucose oil emulsion (Solganal B. product of Schering) was used. In the first week, 5-10 mg of Solganal B were given twice. 10 mg were given twice in the second week, and thereafter the doses were gradually increased until the total dosage reached 1.0~1.5g. By the combined balneo- and chrysotherapy applied to the 93 cases of rheumatoid arthritis, we obtained the results as follows. 1. The improvement in the erythrocyte sedimentation rate was observed in 77% of them. 2. The improvement in the CRP test was observed in 46%, but the aggravation was found in 8.7% of their conditions. 3. There were 53 cases (57%) whose RA-test was either weakened or turned negative. 4. Judging from the changes in the erythrocyte sedimentation rate and the doses of gold thioglucose given, the effects of such a treatment appear around the tenth week after the start of the treatment and it seems that the total dosage of 500 mg and over gold salt is most appropriate. 5. By the combined treatment there were 10 (48%) of 21 cases whose conditions had improved well enough as to withdraw corticosteroids treatment and remaining 11 cases (52%) who had improved to the extent where we could reduce the amount of corticosteroids. 6. By applying the evaluating system of HASHIMOTO, the efficacy rate of the treatment proves to be 89% in the cases given over 500 mg gold thioglucose, and out of these 49% showed a marked effect. Therefore, it seems that the optimal dosage is over 500 mg. 7. These results amply indicate that for the treatment of chronic rheumatoid arthritis the balneotherapy combined with some organic gold compound or salt (Solganal B in the present study) is highly beneficial.
Publication Title 岡山大学温泉研究所報告
Published Date 1967-12-15
Volume volume37
Start Page 9
End Page 19
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002400927
Author 岡山大学温泉研究所|
Published Date 1967-12-15
Publication Title 岡山大学温泉研究所報告
Volume volume37
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1967-12-15
Publication Title 岡山大学温泉研究所報告
Volume volume37
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1969-03-20
Publication Title 岡山大学温泉研究所報告
Volume volume38
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1969-03-20
Publication Title 岡山大学温泉研究所報告
Volume volume38
Content Type Others
JaLCDOI 10.18926/40181
Title Alternative The determination of serum triglycerides
FullText URL pitsr_038_077_084.pdf
Author Mifune, Masaaki|
Abstract Currently accepted methods for serum triglycerides, namely, the manual modified VAN HANDEL-KAWADE method and the semi-automated LOFLAND method, were critically examined. Since the absorbents, the quality of sulfuric acid, the processes of shaking, extraction, saponification, removal of ethanol after saponification, and the stability of colored solution appear to be essential factors governing precision and accuracy of the determination, the effects of these factors were studied. It was found that the process of removal of ethanol was most important. To obtain the reproducible absorption, it is most advantageous to evaporate off ethanol from the solution of pH⋍6 on an oil bath at 101℃. As a result of re-examination on LOFLAND'S semi-automated method using a standard AutoAnalyzer, it is shown that the mixing coils can be omitted, thereby making the analysis possible in 18 -19 minutes (In the original LOFLAND'S method it takes more than 22 minutes). In addition, this modification results in smaller amount of chromotropoc acid reagent necessary (2.9 ml/min. as compared to 5 ml/min. in the original method). The determination rate in this modified method is 25 samples per hour. The average values, standard deviations, and coefficients of variance for the same serum sample for ten analyses according to the suggested manual method were 55.0 mg/dl, 1.83 mg/dl, and 4.69%, respectively, and those according to the suggested semi-automated method were 53.6 mg/dl, 1.78mg/dl and 4.68%, respectively.
Publication Title 岡山大学温泉研究所報告
Published Date 1969-03-20
Volume volume38
Start Page 77
End Page 84
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398501