FullText URL | blood_119_1_285.pdf |
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Author | Nishimori, Hisakazu| Maeda, Yoshinobu| Teshima, Takanori| Sugiyama, Haruko| Kobayashi, Koichiro| Yamasuji, Yoshiko| Kadohisa, Sachiyo| Uryu, Hidetaka| Takeuchi, Kengo| Tanaka, Takehiro| Yoshino, Tadashi| Iwakura, Yoichiro| Tanimoto, Mitsune| |
Note | This research was originally published in Blood. 2012. © the American Society of Hematology.| |
Published Date | 2012-01-05 |
Publication Title | Blood |
Volume | volume119 |
Issue | issue1 |
Start Page | 285 |
End Page | 295 |
Content Type | Journal Article |
language | 英語 |
OAI-PMH Set | 岡山大学 |
Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
File Version | publisher |
PubMed ID | 22077062 |
DOI | 10.1182/blood-2011-01-332478 |
Web of Sience KeyUT | 000299012400035 |
Related Url | https://doi.org/10.1182/blood-2011-01-332478 |
FullText URL | K0005304 other1.pdf |
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Author | Igawa, Takuro| Sato, Yasuharu| Takata, Katsuyoshi| Iwaki, Noriko| Tanaka, Takehiro| Asano, Naoko| Maeda, Yoshinobu| Orita, Yorihisa| Nakamura, Naoya| Nakamura, Shigeo| Yoshino, Tadashi| |
Keywords | Cyclin D2 CD5 Diffuse large B-cell lymphoma |
Note | 学位審査副論文 |
Published Date | 2013-05-15 |
Publication Title | Diagnostic Pathology |
Volume | volume8 |
Publisher | BioMed Central |
Start Page | 81 |
ISSN | 1746-1596 |
Content Type | Journal Article |
language | 英語 |
OAI-PMH Set | 岡山大学 |
Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
File Version | publisher |
PubMed ID | 23675804 |
DOI | 10.1186/1746-1596-8-81 |
Web of Sience KeyUT | 000319266300002 |
Related Url | https://doi.org/10.1186/1746-1596-8-81 http://ousar.lib.okayama-u.ac.jp/54287 |
JaLCDOI | 10.18926/AMO/54978 |
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FullText URL | 71_2_105.pdf |
Author | Shinya, Takayoshi| Tanaka, Takashi| Soh, Junichi| Matsushita, Toshi| Sato, Shuhei| Toyooka, Shinichi| Yoshino, Tadashi| Miyoshi, Shinichiro| Kanazawa, Susumu| |
Abstract | We retrospectively assessed the dual-time-point (DTP) F-18 FDG PET/CT findings of thymic epithelial neoplasms (TENs) and investigated the diagnostic capacity of PET/CT compared to that of CT for predicting carcinoma. We calculated the ratio of the standardized uptake value of the tumor and that of the aortic arch (T/M ratio) for both the 90-min early scan and the 2-h delayed scan in 56 TEN patients. We used a multivariate logistic regression (MLR) analysis to estimate the CT features of carcinoma. We compared the diagnostic capacities of PET/CT and chest CT using receiver operating characteristic (ROC) analyses. The ROC curve revealed that the appropriate cut-off T/M ratio value for the highest accuracy was 2.39 with 75.0% accuracy. The area under the curve (AUC) was 0.855. The statistical analyses for DTP scans of 35 TEN patients demonstrated 74.3% accuracy and 0.838 AUC for the early scan versus 82.9% and 0.825 for the delayed scan. The MLR analysis indicated that mediastinal fat infiltration was a predictor of carcinoma. The ROC curve obtained for the model yielded an AUC of 0.853. Delayed scanning could improve the diagnostic capacity for carcinoma. The T/M ratio and mediastinal fat infiltration are predictive of carcinoma with moderate diagnostic accuracy. |
Keywords | thymic epithelial neoplasm thymic carcinoma thymoma dual-time-point PET/CT chest CT |
Amo Type | Original Article |
Published Date | 2017-04 |
Publication Title | Acta Medica Okayama |
Volume | volume71 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 105 |
End Page | 112 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | 英語 |
Copyright Holders | CopyrightⒸ 2017 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 28420891 |
JaLCDOI | 10.18926/AMO/54815 |
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FullText URL | 70_6_503.pdf |
Author | Kanazawa, Yui| Yamashita, Yuka| Fujiwara, Mitsuhiro| Muraoka, Michiko| Washio, Kana| Kanamitsu, Kiichiro| Ishida, Hisashi| Nakano, Takae| Yamada, Miho| Horibe, Keizo| Tanaka, Takehiro| Yoshino, Tadashi| Shimada, Akira| |
Abstract | Childhood anaplastic large cell lymphoma (ALCL) accounts for approx. 10–30 of cases of non-Hodgkin lymphoma, and the ALCL99 study reported 60–75 disease-free survival; however, a relatively high relapse rate was observed (25–30 ). We report 2 patients with Stage III ALCL who relapsed 6–18 months after the end of ALCL99 chemotherapy. A retrospective molecular analysis identified the nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) fusion gene in the first diagnostic bone marrow samples taken from both patients. However, antibodies against the ALK protein appeared to be relatively low in the serum of both patients (×100 and ×750). An increase in chemotherapy intensity may be beneficial if Stage III ALCL patients are shown to be NPM-ALK chimera-positive in the first diagnostic bone marrow sample. |
Keywords | ALCL NPM-ALK fusion lymphoma |
Amo Type | Case Report |
Published Date | 2016-12 |
Publication Title | Acta Medica Okayama |
Volume | volume70 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 503 |
End Page | 506 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | 英語 |
Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 28003677 |
Title Alternative | A primary diffuse large B-cell lymphoma of the liver treated with R-CHOP regimen |
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FullText URL | 127_209.pdf |
Author | Okada, Hiroshi| Fujii, Soichiro| Watanabe, Kentaro| Shigematu, Terunobu| Miyashita, Katsuhiro| Okazaki, Morihiro| Kobashi, Haruhiko| Yokoyama, Motohiro| Yoshino, Tadashi| |
Abstract | A 78-year-old Japanese man was referred to our hospital after experiencing black feces. No abnormal finding was detected in the endoscopic examination of his stomach and large intestines. Computed tomography (CT) of the abdomen revealed a tumor lesion in the right lobe of the liver. A needle biopsy of the tumor under ultrasound guidance was performed. A pathological examination of the biopsy specimen showed a diffuse proliferation of lymphoma cells, which was compatible with diffuse large B-cell lymphoma (DLBCL). F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)-CT demonstrated increased FDG uptake only in the liver tumor. We made the diagnosis of primary DLBCL of the liver. After six cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP), the patient achieved complete remission and has maintained remission for 2 years since the diagnosis. The R-CHOP regimen might be effective therapy for primary DLBCL of the liver. |
Keywords | びまん性大細胞型B細胞リンパ腫(diffuse large B-cell lymphoma) 肝臓(liver) R-CHOP療法(R-CHOP regimen) |
Publication Title | 岡山医学会雑誌 |
Published Date | 2015-12-01 |
Volume | volume127 |
Issue | issue3 |
Start Page | 209 |
End Page | 212 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.127.209 |
language | 日本語 |
Copyright Holders | Copyright (c) 2015 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.127.209 |
NAID | 130005116809 |
JaLCDOI | 10.18926/AMO/53676 |
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FullText URL | 69_5_301.pdf |
Author | Seki, Anna| Iwamuro, Masaya| Yoshioka, Masao| Fujii, Nobuharu| Okada, Hiroyuki| Nose, Soichiro| Takata, Katsuyoshi| Yoshino, Tadashi| Yamamoto, Kazuhide| |
Abstract | A 41-year-old woman was diagnosed with duodenal follicular lymphoma. She had no other lesions and was assigned to a "watch and wait" policy. Swelling of the inguinal lymph nodes appeared 45 months later, and rituximab monotherapy resulted in complete remission. However, follicular lymphoma recurred in the stomach, rectum and mesenteric and external iliac lymph nodes 81 months after the therapy. The patient received rituximab monotherapy again and has remained in complete remission in the fifteenth year after the initial diagnosis. This case suggests the usefulness of rituximab monotherapy in the long-term management of intestinal follicular lymphoma. |
Keywords | follicular lymphoma duodenum rituximab |
Amo Type | Case Report |
Published Date | 2015-10 |
Publication Title | Acta Medica Okayama |
Volume | volume69 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 301 |
End Page | 306 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | 英語 |
Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 26490027 |
Web of Sience KeyUT | 000365519600006 |
Author | Kyotaro, Ohno| Yasuharu, Sato| Koh-ichi, Ohshima| Katsuyoshi, Takata| Tomoko, Miyata-Takata| Mai, Takeuchi| Yuka, Gion| Tomoyasu, Tachibana| Yorihisa, Orita| Toshihiro, Ito| Steven, H. Swerdlow| Tadashi, Yoshino| |
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Published Date | 2015 |
Publication Title | Scientific Reports |
Volume | volume5 |
Content Type | Journal Article |