Tazawa, Hiroshi - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Local oncolytic adenovirotherapy produces an abscopal effect via tumor-derived extracellular vesicles

Author	Kakiuchi, Yoshihiko\| Kuroda, Shinji\| Kanaya, Nobuhiko\| Kumon, Kento\| Tsumura, Tomoko\| Hashimoto, Masashi\| Yagi, Chiaki\| Sugimoto, Ryoma\| Hamada, Yuki\| Kikuchi, Satoru\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Tazawa, Hiroshi\| Urata, Yasuo\| Fujiwara, Toshiyoshi\|
Keywords	Extracellular vesicles Exosome Abscopal effect Oncolytic adenovirus Local treatment Systemic delivery Drug delivery system
Note	© 2021 The American Society of Gene and Cell Therapy. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.ymthe.2021.05.015] .<br> This fulltext is available in May. 2022.\|
Published Date	2021-05-21
Publication Title	Molecular Therapy
Volume	volume29
Issue	issue10
Publisher	The American Society of Gene and Cell Therapy
Start Page	2920
End Page	2930
ISSN	15250016
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The American Society of Gene and Cell Therapy.
File Version	author
PubMed ID	34023506
DOI	10.1016/j.ymthe.2021.05.015
Related Url	isVersionOf https://doi.org/10.1016/j.ymthe.2021.05.015

Phase I dose-escalation study of endoscopic intratumoral injection of OBP-301 (Telomelysin) with radiotherapy in oesophageal cancer patients unfit for standard treatments

Author	Shirakawa, Yasuhiro\| Tazawa, Hiroshi\| Tanabe, Shunsuke\| Kanaya, Nobuhiko\| Noma, Kazuhiro\| Koujima, Takeshi\| Kashima, Hajime\| Kato, Takuya\| Kuroda, Shinji\| Kikuchi, Satoru\| Kagawa, Shunsuke\| Katsui, Kuniaki\| Kanazawa, Susumu\| Urata, Yasuo\| Fujiwara, Toshiyoshi\|
Keywords	Telomerase adenovirus radiotherapy esophageal cancer immunotherapy
Note	This is an Accepted Manuscript of an article published by Elsevier.<br> This fulltext is available in July 2022.\|
Published Date	2021-8
Publication Title	European Journal of Cancer
Volume	volume153
Publisher	Elsevier BV
Start Page	98
End Page	108
ISSN	0959-8049
NCID	AA1075407X
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Elsevier Ltd.
File Version	author
PubMed ID	34153720
DOI	10.1016/j.ejca.2021.04.043
Web of Science KeyUT	000686051300013
Related Url	isVersionOf https://doi.org/10.1016/j.ejca.2021.04.043

Oncolytic virotherapy reverses chemoresistance in osteosarcoma by suppressing MDR1 expression

Author	Sugiu, Kazuhisa\| Tazawa, Hiroshi\| Hasei, Joe\| Yamakawa, Yasuaki\| Omori, Toshinori\| Komatsubara, Tadashi\| Mochizuki, Yusuke\| Kondo, Hiroya\| Osaki, Shuhei\| Fujiwara, Tomohiro\| Yoshida, Aki\| Kunisada, Toshiyuki\| Ueda, Koji\| Urata, Yasuo\| Kagawa, Shunsuke\| Ozaki, Toshifumi\| Fujiwara, Toshiyoshi\|
Keywords	Osteosarcoma Chemoresistance MDR1 Oncolytic adenovirus p53
Note	This is a post-peer-review, pre-copyedit version of an article published in Cancer Chemotherapy and Pharmacology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00280-021-04310-5<br> This fulltext is available in June 2022.\|
Published Date	2021-6-10
Publication Title	Cancer Chemotherapy and Pharmacology
Publisher	Springer Science and Business Media LLC
ISSN	0344-5704
NCID	AA00598397
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	34114067
DOI	10.1007/s00280-021-04310-5
Web of Science KeyUT	000659839700002
Related Url	isVersionOf https://doi.org/10.1007/s00280-021-04310-5

Oncolytic virotherapy promotes radiosensitivity in soft tissue sarcoma by suppressing anti-apoptotic MCL1 expression

FullText URL	fulltext.pdf
Author	Omori, Toshinori\| Tazawa, Hiroshi\| Yamakawa, Yasuaki\| Osaki, Shuhei\| Hasei, Joe\| Sugiu, Kazuhisa\| Komatsubara, Tadashi\| Fujiwara, Tomohiro\| Yoshida, Aki\| Kunisada, Toshiyuki\| Urata, Yasuo\| Kagawa, Shunsuke\| Ozaki, Toshifumi\| Fujiwara, Toshiyoshi\|
Keywords	Gastric yolk sac Tumor-like carcinoma Adenocarcinoma; Alpha-fetoprotein
Published Date	2021-04-22
Publication Title	PLoS ONE
Volume	volume16
Issue	issue4
Publisher	Public Library Science
Start Page	e0250643
ISSN	1932-6203
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Omori et al.
File Version	publisher
PubMed ID	33886686
NAID	120007045007
DOI	10.1371/journal.pone.0250643
Web of Science KeyUT	000644138300019
Related Url	isVersionOf https://doi.org/10.1371/journal.pone.0250643

Role of Tumor-Associated Macrophages in Sarcomas

FullText URL	fulltext.pdf
Author	Fujiwara, Tomohiro\| Healey, John\| Ogura, Koichi\| Yoshida, Aki\| Kondo, Hiroya\| Hata, Toshiaki\| Kure, Miho\| Tazawa, Hiroshi\| Nakata, Eiji\| Kunisada, Toshiyuki\| Fujiwara, Toshiyoshi\| Ozaki, Toshifumi\|
Keywords	sarcoma tumor-associated macrophage prognosis clinical trial immunotherapy
Published Date	2021-03-03
Publication Title	Cancers
Volume	volume13
Issue	issue5
Publisher	MDPI
Start Page	1086
ISSN	2072-6694
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	33802565
NAID	120007008531
DOI	10.3390/cancers13051086
Web of Science KeyUT	000627955600001
Related Url	isVersionOf https://doi.org/10.3390/cancers13051086

Extracellular vesicles shed from gastric cancer mediate protumor macrophage differentiation

FullText URL	fulltext.pdf
Author	Ito, Atene\| Kagawa, Shunsuke\| Sakamoto, Shuichi\| Kuwada, Kazuya\| Kajioka, Hiroki\| Yoshimoto, Masashi\| Kikuchi, Satoru\| Kuroda, Shinji\| Yoshida, Ryuichi\| Tazawa, Hiroshi\| Fujiwara, Toshiyoshi\|
Keywords	Extracellular vesicles Gastric cancer Tumor-associated macrophages Tumor microenvironment
Published Date	2021-01-28
Publication Title	BMC Cancer
Volume	volume21
Issue	issue1
Publisher	BMC
Start Page	102
ISSN	1471-2407
NCID	AA12034763
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s). 2021
File Version	publisher
PubMed ID	33509150
DOI	10.1186/s12885-021-07816-6
Web of Science KeyUT	000615987400002
Related Url	isVersionOf https://doi.org/10.1186/s12885-021-07816-6

Fibroblast activation protein targeted near infrared photoimmunotherapy (NIR PIT) overcomes therapeutic resistance in human esophageal cancer

FullText URL	fulltext.pdf
Author	Katsube, Ryoichi\| Noma, Kazuhiro\| Ohara, Toshiaki\| Nishiwaki, Noriyuki\| Kobayashi, Teruki\| Komoto, Satoshi\| Sato, Hiroaki\| Kashima, Hajime\| Kato, Takuya\| Kikuchi, Satoru\| Tazawa, Hiroshi\| Kagawa, Shunsuke\| Shirakawa, Yasuhiro\| Kobayashi, Hisataka\| Fujiwara, Toshiyoshi\|
Published Date	2021-01-18
Publication Title	Scientific Reports
Volume	volume11
Issue	issue1
Publisher	Nature Research
Start Page	1693
ISSN	2045-2322
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021
File Version	publisher
PubMed ID	33462372
DOI	10.1038/s41598-021-81465-4
Web of Science KeyUT	000612156600008
Related Url	isVersionOf https://doi.org/10.1038/s41598-021-81465-4

Real-Time Fluorescence Image-Guided Oncolytic Virotherapy for Precise Cancer Treatment

FullText URL	fulltext.pdf
Author	Yano, Shuya\| Tazawa, Hiroshi\| Kishimoto, Hiroyuki\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\| Hoffman, Robert M.\|
Keywords	cancer cell cycle fluorescent proteins FUCCI imaging adenovirus oncolytic virotherapy cancer stem cell mouse model orthotopic
Published Date	2021-01-17
Publication Title	International Journal of Molecular Sciences
Volume	volume22
Issue	issue2
Publisher	MDPI
Start Page	879
ISSN	1422-0067
NCID	AA12038549
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	33477279
DOI	10.3390/ijms22020879
Web of Science KeyUT	000611296000001
Related Url	isVersionOf https://doi.org/10.3390/ijms22020879

Targeting neutrophil extracellular traps with thrombomodulin prevents pancreatic cancer metastasis

Author	Kajioka, Hiroki\| Kagawa, Shunsuke\| Ito, Atene\| Yoshimoto, Masashi\| Sakamoto, Shuichi\| Kikuchi, Satoru\| Kuroda, Shinji\| Yoshida, Ryuichi\| Umeda, Yuzo\| Noma, Kazuhiro\| Tazawa, Hiroshi\| Fujiwara, Toshiyoshi\|
Keywords	HMGB1 Epithelial to mesenchymal transition Phorbol 12-myristate 13-acetate Ischemia-reperfusion model
Note	This fulltext is available in January, 2022.\|
Published Date	2021-01-28
Publication Title	Cancer Letters
Volume	volume497
Publisher	Elsevier
Start Page	1
End Page	3
ISSN	0304-3835
NCID	AA00598513
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	33065249
DOI	10.1016/j.canlet.2020.10.015
Web of Science KeyUT	000596072900001
Related Url	isVersionOf https://doi.org/10.1016/j.canlet.2020.10.015

Telomerase-specific oncolytic immunotherapy for promoting efficacy of PD-1 blockade in osteosarcoma

FullText URL	fulltext.pdf figures.pdf SuppleFigures.pdf
Author	Mochizuki, Yusuke\| Tazawa, Hiroshi\| Demiya, Koji\| Kure, Miho\| Kondo, Hiroya\| Komatsubara, Tadashi\| Sugiu, Kazuhisa\| Hasei, Joe\| Yoshida, Aki\| Kunisada, Toshiyuki\| Urata, Yasuo\| Kagawa, Shunsuke\| Ozaki, Toshifumi\| Fujiwara, Toshiyoshi\|
Keywords	Oncolytic adenovirus hTERT Immunogenic cell death ATP CD8
Note	This is a post-peer-review, pre-copyedit version of an article published in Cancer Immunology, Immunotherapy. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00262-020-02774-7.\|
Published Date	2020-11-05
Publication Title	Cancer Immunology, Immunotherapy
Publisher	Springer
Start Page	0340-7004
NCID	AA00598499
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	33151368
DOI	10.1007/s00262-020-02774-7
Web of Science KeyUT	000586350500002
Related Url	isVersionOf https://doi.org/10.1007/s00262-020-02774-7

FUCCI Real-Time Cell-Cycle Imaging as a Guide for Designing Improved Cancer Therapy: A Review of Innovative Strategies to Target Quiescent Chemo-Resistant Cancer Cells

FullText URL	fulltext.pdf
Author	Yano, Shuya\| Tazawa, Hiroshi\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\| Hoffman, Robert M.\|
Keywords	cell cycle fluorescent proteins FUCCI imaging targeted cancer therapy quiescent cancer cells decoy chemotherapy
Published Date	2020-09-17
Publication Title	Cancers
Volume	volume12
Issue	issue9
Publisher	MDPI
Start Page	2655
ISSN	2072-6694
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	32957652
DOI	10.3390/cancers12092655
Web of Science KeyUT	000580315800001
Related Url	isVersionOf https://doi.org/10.3390/cancers12092655

Elimination of MYCN-Amplified Neuroblastoma Cells by Telomerase-Targeted Oncolytic Virus via MYCN Suppression

FullText URL	fulltext.pdf
Author	Tanimoto, Terutaka\| Tazawa, Hiroshi\| Ieda, Takeshi\| Nouso, Hiroshi\| Tani, Morimichi\| Oyama, Takanori\| Urata, Yasuo\| Kagawa, Shunsuke\| Noda, Takuo\| Fujiwara, Toshiyoshi\|
Keywords	neuroblastoma MYCN hTERT adenovirus E2F1
Published Date	2020-09-25
Publication Title	Molecular Therapy - Oncolytics
Volume	volume18
Publisher	Cell Press
Start Page	14
End Page	23
ISSN	2372-7705
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Author(s).
File Version	publisher
PubMed ID	32637577
DOI	10.1016/j.omto.2020.05.015
Web of Science KeyUT	000575168700002
Related Url	isVersionOf https://doi.org/10.1016/j.omto.2020.05.015

Boosting Replication and Penetration of Oncolytic Adenovirus by Paclitaxel Eradicate Peritoneal Metastasis of Gastric Cancer

FullText URL	fulltext.pdf
Author	Ishikawa, Wataru\| Kikuchi, Satoru\| Ogawa, Toshihiro\| Tabuchi, Motoyasu\| Tazawa, Hiroshi\| Kuroda, Shinji\| Noma, Kazuhiro\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Urata, Yasuo\| Fujiwara, Toshiyoshi\|
Keywords	peritoneal metastasis adenovirus gastric cancer intraperitoneal chemotherapy paclitaxel oncolytic virus
Published Date	2020-09-25
Publication Title	Molecular Therapy - Oncolytics
Volume	volume18
Publisher	Cell Press
Start Page	262
End Page	271
ISSN	2372-7705
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Author(s).
File Version	publisher
PubMed ID	32728614
DOI	10.1016/j.omto.2020.06.021
Web of Science KeyUT	000575168700023
Related Url	isVersionOf https://doi.org/10.1016/j.omto.2020.06.021

Oncolytic Virus-Mediated Targeting of the ERK Signaling Pathway Inhibits Invasive Propensity in Human Pancreatic Cancer

FullText URL	fulltext.pdf
Author	Koujima, Takeshi\| Tazawa, Hiroshi\| Ieda, Takeshi\| Araki, Hiroyuki\| Fushimi, Takuro\| Shoji, Ryohei\| Kuroda, Shinji\| Kikuchi, Satoru\| Yoshida, Ryuichi\| Umeda, Yuzo\| Teraishi, Fuminori\| Urata, Yasuo\| Mizuguchi, Hiroyuki\| Fujiwara, Toshiyoshi\|
Published Date	2020-06-26
Publication Title	Molecular Therapy - Oncolytics
Volume	volume17
Publisher	Cell Press
Start Page	107
End Page	117
ISSN	2372-7705
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Author(s).
File Version	publisher
PubMed ID	32322667
DOI	10.1016/j.omto.2020.03.016
Web of Science KeyUT	000544101600010
Related Url	isVersionOf https://doi.org/10.1016/j.omto.2020.03.016

Bone and Soft-Tissue Sarcoma: A New Target for Telomerase-Specific Oncolytic Virotherapy

FullText URL	fulltext.pdf
Author	Tazawa, Hiroshi\| Hasei, Joe\| Yano, Shuya\| Kagawa, Shunsuke\| Ozaki, Toshifumi\| Fujiwara, Toshiyoshi\|
Keywords	oncolytic adenovirus hTERT autophagy GFP p53
Published Date	2020-02-18
Publication Title	Cancers
Volume	volume12
Issue	issue2
Publisher	MDPI
ISSN	2072-6694
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	32085583
DOI	10.3390/cancers12020478
Web of Science KeyUT	000522477300224
Related Url	isVersionOf https://doi.org/10.3390/cancers12020478

Immune Modulation by Telomerase-Specific Oncolytic Adenovirus Synergistically Enhances Antitumor Efficacy with Anti-PD1 Antibody

FullText URL	fulltext.pdf Graphical_Abstract.pptx Figure1-6.pdf Supp_Info.pdf
Author	Kanaya, Nobuhiko\| Kuroda, Shinji\| Kakiuchi, Yoshihiko\| Kumon, Kento\| Tsumura, Tomoko\| Hashimoto, Masashi\| Morihiro, Toshiaki\| Kubota, Tetsushi\| Aoyama, Katsuyuki\| Kikuchi, Satoru\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Tazawa, Hiroshi\| Mizuguchi, Hiroyuki\| Urata, Yasuo\| Fujiwara, Toshiyoshi\|
Keywords	immune checkpoint programmed death-1 oncolytic adenovirus combined immunotherapy immunogenic cell death tumor infiltrating lymphocytes CD8 abscopal effect
Published Date	2020-01-10
Publication Title	Molecular Therapy
Volume	volume28
Issue	issue3
Publisher	Cell Press
Start Page	794
End Page	804
ISSN	15250016
NCID	AA11475060
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	31991110
DOI	10.1016/j.ymthe.2020.01.003
Web of Science KeyUT	000518887200012
Related Url	isVersionOf https://doi.org/10.1016/j.ymthe.2020.01.003

Visualization of epithelial-mesenchymal transition in an inflammatory microenvironment-colorectal cancer network

Author	Ieda, Takeshi\| Tazawa, Hiroshi\| Okabayashi, Hiroki\| Yano, Shuya\| Shigeyasu, Kunitoshi\| Kuroda, Shinji\| Ohara, Toshiaki\| Noma, Kazuhiro\| Kishimoto, Hiroyuki\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Shirakawa, Yasuhiro\| Saitou, Takashi\| Imamura, Takeshi\| Fujiwara, Toshiyoshi\|
Published Date	2019-11-8
Publication Title	Scientific Reports
Volume	volume9
Publisher	Nature Publishing Group
Start Page	16378
ISSN	2045-2322
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2019
File Version	publisher
PubMed ID	31705021
DOI	10.1038/s41598-019-52816-z
Web of Science KeyUT	000495372900001
Related Url	isVersionOf https://doi.org/10.1038/s41598-019-52816-z

PD-L1 expression combined with microsatellite instability/CD8+tumor infiltrating lymphocytes as a useful prognostic biomarker in gastric cancer

FullText URL	SR9_1_4633.pdf
Author	Morihiro, Toshiaki\| Kuroda, Shinji\| Kanaya, Nobuhiko\| Kakiuchi, Yoshihiko\| Kubota, Tetsushi\| Aoyama, Katsuyuki\| Tanaka, Takehiro\| Kikuch, Satoru\| Nagasaka, Takeshi\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Tazawa, Hiroshi\| Fujiwara, Toshiyoshi\|
Published Date	2019-3-15
Publication Title	Scientific Reports
Volume	volume9
Publisher	Nature Publishing Group
Start Page	4633
ISSN	2045-2322
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2019
File Version	publisher
PubMed ID	30874607
DOI	10.1038/s41598-019-41177-2
Web of Science KeyUT	000461303000015
Related Url	isVersionOf https://doi.org/10.1038/s41598-019-41177-2

A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness

FullText URL	cancers_11_2_177.pdf
Author	Katsura, Yuki\| Ohara, Toshiaki\| Noma, Kazuhiro\| Ninomiya, Takayuki\| Kashima, Hajime\| Kato, Takuya\| Sato, Hiroaki\| Komoto, Satoshi\| Narusaka, Toru\| Tomono, Yasuko\| Xing, Boyi\| Chen, Yuehua\| Tazawa, Hiroshi\| Kagawa, Shunsuke\| Shirakawa, Yasuhiro\| Kasai , Tomonari\| Seno, Masaharu\| Matsukawa, Akihiro\| Fujiwara, Toshiyoshi\|
Keywords	cancer stem cells combination therapy iron stemness
Published Date	2019-02-03
Publication Title	Cancers
Volume	volume11
Issue	issue2
Publisher	MDPI
Start Page	177
ISSN	2072-6694
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 by the authors
File Version	publisher
PubMed ID	30717462
DOI	10.3390/cancers11020177
Web of Science KeyUT	000460747200051
Related Url	isVersionOf https://doi.org/10.3390/cancers11020177

Intraperitoneal cancer-immune microenvironment promotes peritoneal dissemination of gastric cancer

FullText URL	OncoImmunol_8_12_1671760.pdf
Author	Sakamoto, Shuichi\| Kagawa, Shunsuke\| Kuwada, Kazuya\| Ito, Atene\| Kajioka, Hiroki\| Kakiuchi, Yoshihiko\| Watanabe, Megumi\| Kagawa, Tetsuya\| Yoshida, Ryuichi\| Kikuchi, Satoru\| Kuroda, Shinji\| Tazawa, Hiroshi\| Fujiwara, Toshiyoshi\|
Keywords	Gastric cancer tumor-associated macrophages tumor microenvironment peritoneal dissemination
Published Date	2019-10-22
Publication Title	OncoImmunology
Volume	volume8
Issue	issue12
Publisher	TAYLOR & FRANCIS
Start Page	e1671760
ISSN	2162402X
Content Type	Journal Article
language	英語
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 The Author(s).
File Version	publisher
DOI	10.1080/2162402X.2019.1671760
Web of Science KeyUT	000494085400001
Related Url	isVersionOf https://doi.org/10.1080/2162402X.2019.1671760