JaLCDOI | 10.18926/AMO/30794 |
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FullText URL | fulltext.pdf |
Author | Nagoshi, Mitsuru| Hashizume, Hiroyuki| Nishida, Keiichiro| Takagoshi, Hidekazu| Pu, Jean| Inoue, Hajime| |
Abstract | Sixty-seven trigger fingers of 58 idiopathic and hemodialysis patients were treated by percutaneous A1-pulley release technique. Severity of triggering was classified into five grades for treatment selection and prediction of possible results. Results were excellent in 41 fingers, good in 9, fair in 7, and poor in 10, requiring additional treatment. The results of the lower grades were better, and those of the higher grades were poor. Excellent or good results appeared to depend on the proper selection of the patients according to the grading system and confirmation of triggering disappearance just after the release. There were neither infections nor neuro-vascular deficits after treatment. Compared to conventional open release, this treatment was found to be more useful from the standpoints of ease and safety of the technique, and the patients' quick return to normal life. |
Keywords | trigger finger percutaneous release idiopathic hemodialysis |
Amo Type | Article |
Publication Title | Acta Medica Okayama |
Published Date | 1997-06 |
Volume | volume51 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 155 |
End Page | 158 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
File Version | publisher |
Refereed | True |
PubMed ID | 9227795 |
Web of Science KeyUT | A1997XJ12700007 |
JaLCDOI | 10.18926/AMO/30790 |
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FullText URL | fulltext.pdf |
Author | Nanba, Yoshifumi| Nishida, Keiichiro| Yoshikawa, Takeshi| Sato, Toru| Inoue, Hajime| Kuboki, Yoshinori| |
Abstract | The expression of osteonectin (ON) in osteoarthritic articular cartilage was investigated by enzyme immunohistochemistry and colloidal gold immunoelectron microscopy. A total of 96 specimens from 9 knees of 8 patients with osteoarthritis (OA) were examined. In OA cartilage, ON-positive cells varied in distribution and were not seen in all the specimens obtained from the same patient. However, in over half of the specimens (56 of 96), especially in the specimens of Mankin's grades from 4 to 9, which corresponds to relatively early stages of OA, ON was expressed in the cartilage above the calcified layer. On the other hand, ON was detected only in the calcified layer below the tidemark in normal articular cartilage. In addition, colloidal gold immunoelectron microscopy revealed ON in chondrocytes and matrix vesicles (MVs). These findings suggest that ON acts through MVs in the early stages of OA as a significant pathogenetic factor involved in intracartilage calcification, which is known to have a close relationship to the progression of OA. |
Keywords | chondrocalcinosis osteoarthritis osteonection Mankin's histologic-histochemical grading calcification |
Amo Type | Article |
Publication Title | Acta Medica Okayama |
Published Date | 1997-10 |
Volume | volume51 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 239 |
End Page | 243 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
File Version | publisher |
Refereed | True |
PubMed ID | 9359920 |
Web of Science KeyUT | A1997YD65300001 |
JaLCDOI | 10.18926/AMO/30778 |
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FullText URL | fulltext.pdf |
Author | Kinugasa, Kiyoto| Hashizume, Hiroyuki| Nishida, Keiichiro| Shigeyama, Yukio| Inoue, Hajime| |
Abstract | The results of the histological examinations of specimens of the tenosynovium of the flexor tendon, the epineurium and the transverse carpal ligament from two groups of Japanese patients with carpal tunnel syndrome (idiopathic and hemodialysis) were compared. Amyloid deposits, positively identified as β2-microglobulin, appeared in all patients in the long-term hemodialysis group, but in no patients in the idiopathic group. Although the pathogenesis differed between the two groups, both resulted in nerve compression in the carpal tunnel. Therefore, surgical release is considered beneficial for both groups. |
Keywords | carpal tunnel syndrome histopathology clinical results idiopathic hemodialysis |
Amo Type | Article |
Publication Title | Acta Medica Okayama |
Published Date | 1997-04 |
Volume | volume51 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 63 |
End Page | 70 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
File Version | publisher |
Refereed | True |
PubMed ID | 9142342 |
Web of Science KeyUT | A1997WX19600002 |
JaLCDOI | 10.18926/AMO/30753 |
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FullText URL | fulltext.pdf |
Author | Nakatani, Satoru| Naito, Ichiro| Momota, Ryusuke| Hinenoya, Noriko| Horiuchi, Kanji| Nishida, Keiichiro| Ohtsuka, Aiji| |
Abstract | We attempted to prepare colloidal iron within tissues by means of microwave irradiation. Mouse tissue blocks were fixed with a mixture of paraformaldehyde and ferric chloride in a cacodylate buffer, immersed in a cacodylate buffered ferric chloride solution, and irradiated in a microwave processor. Colloidal iron was prepared within tissues or cells, and was observed in the form of electron dense fine granules (1-2 nm in diameter) by transmission electron microscopy. Collagen fibrils in the connective tissue showed colloidal iron deposition at regular periodical intervals. Cells in the splenic tissue showed that fine colloidal granules were deposited on the ribosomes but not on the nuclear chromatin. This finding suggests that ferric ions could not diffuse into the nucleus, which was surrounded by the nuclear envelope. The podocyte processes of the renal glomerulus were stained diffusedly. Though this microwave in situ colloidal iron preparation method has some limitations, it is convenient for use in biomedical specimen preparation in transmission electron microscopy. |
Keywords | colloidal iron microwave histochemistry transmission electron microscopy |
Amo Type | Article |
Publication Title | Acta Medica Okayama |
Published Date | 2006-02 |
Volume | volume60 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 59 |
End Page | 64 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
File Version | publisher |
Refereed | True |
PubMed ID | 16508690 |
Web of Science KeyUT | 000235538900007 |
JaLCDOI | 10.18926/AMO/30749 |
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FullText URL | fulltext.pdf |
Author | Komiyama, Takamitsu| Nishida, Keiichiro| Yorimitsu, Masanori| Doi, Hideyuki| Miyazawa, Shinichi| Kitamura, Ai| Yoshida, Aki| Nasu, Yoshihisa| Abe, Nobuhiro| Ozaki, Toshifumi| |
Abstract | Ossification disturbance in femoral head reportedly is seen in the Spontaneously Hypertensive rats (SHR) between ages of 10 and 20 weeks. We investigated serum and tissue levels of insulin-like growth factor-1 (IGF-1) and vascular endothelial growth factor (VEGF) in SHR relevant to the ossification disturbance and osteonecrosis of the femoral head. Serum levels of IGF-1 and VEGF were significantly lower in SHR than in Wistar Kyoto rats (WKY) at weeks 5, 10, 15 and 20 (p<0.005). The incidence of histological ossification disturbance of the femoral head was higher in SHR (59%) than in WKY (40%) at week 20. Lower serum and local levels of VEGF in SHR appeared to be related to the incomplete ossification of the femoral heads. Immunohistochemical study showed significantly lower numbers of IGF-1 and VEGF positive chondrocytes in the femoral epiphyseal cartilage of SHR than in those of WKY at weeks 10, 15 and 20. Our results suggest that local and/or systemic levels of IGF-1 and VEGF between ages of 5 and 20 weeks might play roles in the pathogenesis of ossifi cation disturbance of the femoral head in SHR. |
Keywords | spontaneous hypertensive rats insulin like growth factor-1 vascular endothelial growth factor ossification disturbance osteonecrosis |
Amo Type | Article |
Publication Title | Acta Medica Okayama |
Published Date | 2006-06 |
Volume | volume60 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 141 |
End Page | 148 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
File Version | publisher |
Refereed | True |
PubMed ID | 16838042 |
Web of Science KeyUT | 000238503600001 |
JaLCDOI | 10.18926/AMO/30384 |
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FullText URL | fulltext.pdf |
Author | Nishida, Keiichiro| Inoue, Hajime| Toda, Kazukiyo| Murakami, Takuro| |
Abstract | Localization of the glycosaminoglycans (GAG) was examined in the synovial membranes of patients with osteoarthritis under light microscopy using a fine cationic colloidal iron staining method combined with enzymatic digestion. Our staining method was very useful for demonstrating the difference in the localization of GAG in regions of the inflammatory site in the osteoarthritic synovial membrane. Hyaluronic acid was mainly located in connective tissues in the surface intercellular and perivascular spaces, chondroitin sulfate A/C in the highly fibrous part of and connective tissue around blood vessels, dermatan sulfate (chondroitin sulfate B) in the subsurface interstitium and vascular endothelial cells and heparan sulfate in part of vascular endothelial cells. No keratan sulfate was detected. GAG is reported to have an important role in cell movement, adherence and aggregation in the inflammatory sites. These findings should be useful for understanding the role of GAG in physiological and pathologic processes of secondary synovitis. |
Keywords | glycosaminoglycan synovial tissue osteoarthritis fine cationic colloidal iron |
Amo Type | Article |
Publication Title | Acta Medica Okayama |
Published Date | 1995-12 |
Volume | volume49 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 287 |
End Page | 294 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
File Version | publisher |
Refereed | True |
PubMed ID | 8770237 |
Web of Science KeyUT | A1995TM84600003 |
Author | Murakami, Takuro| Piao, Da Xun| Ohtsuka, Aiji| Nishida, Keiichiro| |
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Published Date | 1996-10-31 |
Publication Title | 岡山医学会雑誌 |
Volume | volume108 |
Issue | issue9-10 |
Content Type | Journal Article |
Author | 西田 圭一郎| |
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Published Date | 2006-01-04 |
Publication Title | 岡山医学会雑誌 |
Volume | volume117 |
Issue | issue3 |
Content Type | Journal Article |
Author | 西田 圭一郎| |
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Published Date | 1995-09-30 |
Publication Title | |
Content Type | Thesis or Dissertation |