Nishida, Keiichiro - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

LRP4 and Agrin Are Modulated by Cartilage Degeneration and Involved in β-Catenin Signaling in Human Articular Chondrocytes

FullText URL	fulltext.pdf
Author	Naniwa, Shuichi\| Nishida, Keiichiro\| Yoshida, Aki\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Ohtsuki, Takashi\| Hotta, Yoshifumi\| Shimizu, Noriyuki\| Ichikawa, Chinatsu\| Lin, Deting\| Otsuka, Noriaki\| Ozaki, Toshifumi\|
Keywords	osteoarthritis chondrocyte mechanical stress LRP4 Agrin β-catenin SOX9
Published Date	2025-01-24
Publication Title	International Journal of Molecular Sciences
Volume	volume26
Issue	issue3
Publisher	MDPI
Start Page	1007
ISSN	1661-6596
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 by the authors.
File Version	publisher
PubMed ID	39940775
DOI	10.3390/ijms26031007
Web of Science KeyUT	001418599900001
Related Url	isVersionOf https://doi.org/10.3390/ijms26031007

Distribution and Incorporation of Extracellular Vesicles into Chondrocytes and Synoviocytes

FullText URL	fulltext.pdf
Author	Ohtsuki, Takashi\| Sato, Ikumi\| Takashita, Ren\| Kodama, Shintaro\| Ikemura, Kentaro\| Opoku, Gabriel\| Watanabe, Shogo\| Furumatsu, Takayuki\| Yamada, Hiroshi\| Ando, Mitsuru\| Akiyoshi, Kazunari\| Nishida, Keiichiro\| Hirohata, Satoshi\|
Keywords	extracellular vesicles (EVs) chondrocytes synoviocytes osteoarthritis (OA)
Published Date	2024-11-06
Publication Title	International Journal of Molecular Sciences
Volume	volume25
Issue	issue22
Publisher	MDPI
Start Page	11942
ISSN	1661-6596
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
DOI	10.3390/ijms252211942
Web of Science KeyUT	001365437300001
Related Url	isVersionOf https://doi.org/10.3390/ijms252211942

Insomnia among patients with chronic pain A retrospective study

FullText URL	fulltext.pdf
Author	Ueda, Masataka\| Tetsunaga, Tomoko\| Tetsunaga, Tomonori\| Nishida, Keiichiro\| Takatori, Ryo\| Shitozawa, Hisakazu\| Uotani, Koji\| Shinohara, Kennsuke\| Oda, Yoshiaki\| Ozaki, Toshifumi\|
Keywords	AIS cognitive-behavioral therapy EQ5D HADS insomnia pain-liaison outpatient clinic sleep disorders
Published Date	2024-08-09
Publication Title	Medicine
Volume	volume103
Issue	issue32
Publisher	Lippincott, Williams & Wilkins
Start Page	e39113
ISSN	0025-7974
NCID	AA00728867
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 the Author(s).
File Version	publisher
PubMed ID	39121265
DOI	10.1097/MD.0000000000039113
Web of Science KeyUT	001287977800045
Related Url	isVersionOf https://doi.org/10.1097/MD.0000000000039113

Comparison of early clinical outcome in carpal tunnel release - mini-open technique with palmar incision vs. endoscopic technique with wrist crease incision-

FullText URL	fulltext.pdf
Author	Nakamichi, Ryo\| Saito, Taichi\| Shimamura, Yasunori\| Hamada, Masanori\| Nishida, Keiichiro\| Ozaki, Toshifumi\|
Keywords	Carpal tunnel syndrome Mini-open Endoscopy Patient-oriented evaluation
Note	The version of record of this article, first published in BMC Musculoskeletal Disorders, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12891-023-07151-w\|
Published Date	2024-04-01
Publication Title	BMC Musculoskeletal Disorders
Volume	volume25
Issue	issue1
Publisher	BMC
Start Page	251
ISSN	1471-2474
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024.
File Version	publisher
PubMed ID	38561698
DOI	10.1186/s12891-023-07151-w
Web of Science KeyUT	001195650000009
Related Url	isVersionOf https://doi.org/10.1186/s12891-023-07151-w

Inhibitory Effect of a Tankyrase Inhibitor on Mechanical Stress-Induced Protease Expression in Human Articular Chondrocytes

FullText URL	fulltext.pdf
Author	Hotta, Yoshifumi\| Nishida, Keiichiro\| Yoshida, Aki\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Naniwa, Shuichi\| Shimizu, Noriyuki\| Ichikawa, Chinatsu\| Lin, Deting\| Fujiwara, Tomohiro\| Ozaki, Toshifumi\|
Keywords	osteoarthritis chondrocyte mechanical stress tankyrases XAV939 SOX9 ADAMTS-5 MMP-13 IL-1β NF-κB β-catenin
Published Date	2024-01-24
Publication Title	International Journal of Molecular Sciences
Volume	volume25
Issue	issue3
Publisher	MDPI
Start Page	1443
ISSN	1661-6596
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	38338721
DOI	10.3390/ijms25031443
Web of Science KeyUT	001161430700001
Related Url	isVersionOf https://doi.org/10.3390/ijms25031443

High Fracture Rate of AVANTA Silicone Implant Following Arthroplasty of the Thumb MCP Joint of Rheumatoid Arthritis Patients with Boutonniere Deformities

JaLCDOI	10.18926/AMO/66673
FullText URL	78_1_071.pdf
Author	Kaneda, Daisuke\| Nishida, Keiichiro\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Harada, Ryozo\| Hotta, Yoshifumi\| Naniwa, Shuichi\| Ozaki, Toshifumi\|
Abstract	We retrospectively investigated the mid-term outcomes of arthroplasty using the AVANTA silicone implant for thumb metacarpophalangeal (MCP) joints with boutonniere deformity in patients with rheumatoid arthritis (RA). This study involved 36 thumbs of 33 RA patients with a mean follow-up period of 5.1 years (range, 2.0-13.3). Postoperatively, the mean extension was significantly increased and the mean flexion was significantly decreased (p<0.001, p<0.001, respectively), resulting in the mean arc of range of motion (ROM) shifting in the direction of extension after surgery. Implant fracture was observed in 10 thumbs (28%), and 4 of these (11%) underwent revision surgery. The survivorship with implant fracture and revision surgery as endpoints were 73.4% and 91.8% at 5 years, respectively. The preoperative arc of ROM and the postoperative flexion range of the implant-fracture group were significantly greater than those in the no-implant-fracture group (p=0.039, 0.034, respectively). These results suggest the importance of patient education and careful rehabilitation to prevent excessive flexion. Overall, the AVANTA silicone implant showed a relatively high rate of implant fracture at our institute.
Keywords	AVANTA silicone implant boutonniere deformity implant fracture thumb metacarpophalangeal joint arthroplasty rheumatoid arthritis
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2024-02
Volume	volume78
Issue	issue1
Publisher	Okayama University Medical School
Start Page	71
End Page	78
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2024 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	38419317
Web of Science KeyUT	001203658200011

The Effectiveness of Rehabilitation after Open Surgical Release for Trigger Finger: A Prospective, Randomized, Controlled Study

FullText URL	fulltext.pdf
Author	Saito, Taichi\| Nakamichi, Ryo\| Nakahara, Ryuichi\| Nishida, Keiichiro\| Ozaki, Toshifumi\|
Keywords	hand surgery rehabilitation open surgical release trigger finger
Published Date	2023-11-20
Publication Title	Journal of Clinical Medicine
Volume	volume12
Issue	issue22
Publisher	MDPI
Start Page	7187
ISSN	2077-0383
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 by the authors.
File Version	publisher
PubMed ID	38002801
DOI	10.3390/jcm12227187
Web of Science KeyUT	001123419500001
Related Url	isVersionOf https://doi.org/10.3390/jcm12227187

Outcome of unlinked total elbow arthroplasty for rheumatoid arthritis in patients younger than 50 years old

FullText URL	fulltext20230817-03.pdf
Author	Nishida, Keiichiro\| Nasu, Yoshihisa\| Hashizume, Kenzo\| Okita, Shunji\| Nakahara, Ryuichi\| Saito, Taichi\| Ozaki, Toshifumi\| Inoue, Hajime\|
Keywords	Total elbow arthroplasty Rheumatoid arthritis Unlinked elbow Less than fifty years old
Published Date	2023-01-13
Publication Title	Bone & Joint Open
Volume	volume4
Issue	issue1
Publisher	British Editorial Society of Bone & Joint Surgery
Start Page	19
End Page	26
ISSN	2633-1462
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 Author(s) et al.
File Version	publisher
PubMed ID	36636881
DOI	10.1302/2633-1462.41.bjo-2022-0151.r1
Web of Science KeyUT	001042052200001
Related Url	isVersionOf https://doi.org/10.1302/2633-1462.41.BJO-2022-0151.R1

Factors influencing caregiver burden in chronic pain patients: A retrospective study

FullText URL	fulltext.pdf
Author	Tsuji, Hironori\| Tetsunaga, Tomoko\| Tetsunaga, Tomonori\| Misawa, Haruo\| Oda, Yoshiaki\| Takao, Shinichiro\| Nishida, Keiichiro\| Ozaki, Toshifumi\|
Keywords	caregiver burden chronic pain fear-avoidance model self-efficacy Zarit Burden Interview
Published Date	2022-09-30
Publication Title	Medicine
Volume	volume101
Issue	issue39
Publisher	Lippincott Williams & Wilkins
Start Page	e30802
ISSN	0025-7974
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 the Author(s).
File Version	publisher
PubMed ID	36181114
DOI	10.1097/MD.0000000000030802
Web of Science KeyUT	000862039900121
Related Url	isVersionOf https://doi.org/10.1097/MD.0000000000030802

Outcome after resection arthroplasty or shortening oblique osteotomy of the lesser metatarsals combined with arthrodesis of the first metatarsophalangeal joint for severe rheumatoid forefoot deformities

FullText URL	fulltext.pdf
Author	Horita, Masahiro\| Nishida, Keiichiro\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Saiga, Kenta\| Hamada, Masanori\| Ozaki, Toshifumi\|
Keywords	forefoot surgery arthrodesis shortening oblique osteotomy patient-reported outcome rheumatoid arthritis
Published Date	2022-08-07
Publication Title	Journal Of Orthopaedic Surgery
Volume	volume30
Issue	issue2
Publisher	Sage Publications Ltd.
Start Page	10225536221117903
ISSN	1022-5536
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2022
File Version	publisher
PubMed ID	35938600
DOI	10.1177/10225536221117903
Web of Science KeyUT	000839038400001
Related Url	isVersionOf https://doi.org/10.1177/10225536221117903

The association of C-reactive protein with an oxidative metabolite of LDL and its implication in atherosclerosis

FullText URL	fulltext.pdf
Author	Tabuchi, Masako\| Inoue, Katsumi\| Usui-Kataoka, Hitomi\| Kobayashi, Kazuko\| Teramoto, Misako\| Takasugi, Koji\| Shikata, Kenichi\| Yamamura, Masahiro\| Ando, Kenji\| Nishida, Keiichiro\| Kasahara, Junko\| Kume, Noriaki\| Lopez, Luis R.\| Mitsudo, Kazuaki\| Nobuyoshi, Masakiyo\| Yasuda, Tatsuji\| Kita, Toru\| Makino, Hirofumi\| Matsuura, Eiji\|
Keywords	beta 2-glycoprotein I oxidized LDL/beta 2-glycoprotein I complexes diabetes mellitus oxidized LDL
Published Date	2007-04
Publication Title	Journal Of Lipid Research
Volume	volume48
Issue	issue4
Publisher	ELSEVIER
Start Page	768
End Page	781
ISSN	0022-2275
NCID	AA00701215
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2007 by the American Society for Biochemistry and Molecular Biology, Inc.
File Version	publisher
PubMed ID	17261875
DOI	10.1194/jlr.M600414-JLR200
Web of Science KeyUT	000245627100003
Related Url	isVersionOf https://doi.org/10.1194/jlr.M600414-JLR200

Bone microarchitectural analysis using ultra-high-resolution CT in tiger vertebra and human tibia

FullText URL	fulltext.pdf
Author	Inai, Ryota\| Nakahara, Ryuichi\| Morimitsu, Yusuke\| Akagi, Noriaki\| Marukawa, Youhei\| Matsushita, Toshi\| Tanaka, Takashi\| Tada, Akihiro\| Hiraki, Takao\| Nasu, Yoshihisa\| Nishida, Keiichiro\| Ozaki, Toshifumi\| Kanazawa, Susumu\|
Keywords	Osteoporosis Bone density Tomography (x-ray computed) X-ray microtomography
Published Date	2021-01-28
Publication Title	European Radiology Experimental
Volume	volume4
Issue	issue1
Publisher	Springer nature
Start Page	4
ISSN	2509-9280
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s). 2020
File Version	publisher
PubMed ID	31993864
DOI	10.1186/s41747-019-0135-0
Web of Science KeyUT	000705622700001
Related Url	isVersionOf https://doi.org/10.1186/s41747-019-0135-0

RANKL expression in chondrocytes and its promotion by lymphotoxin-alpha in the course of cartilage destruction during rheumatoid arthritis

FullText URL	fulltext.pdf
Author	Takeshita, Ayumu\| Nishida, Keiichiro\| Yoshida, Aki\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Kaneda, Daisuke\| Ohashi, Hideki\| Ozaki, Toshifumi\|
Published Date	2021-07-07
Publication Title	PLOS ONE
Volume	volume16
Issue	issue7
Publisher	Public Library Science
Start Page	e0254268
ISSN	1932-6203
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Takeshita et al.
File Version	publisher
PubMed ID	34234380
DOI	10.1371/journal.pone.0254268
Web of Science KeyUT	000674294100020
Related Url	isVersionOf https://doi.org/10.1371/journal.pone.0254268

A Novel Radiographic Measurement Method for the Evaluation of Metatarsophalangeal Joint Dislocation of the Lesser Toe in Patients with Rheumatoid Arthritis

FullText URL	fulltext.pdf
Author	Ohashi, Hideki\| Nishida, Keiichiro\| Nasu, Yoshihisa\| Saiga, Kenta\| Nakahara, Ryuichi\| Horita, Masahiro\| Okita, Shunji\| Ozaki, Toshifumi\|
Keywords	lesser toe metatarsophalangeal joint rheumatoid arthritis radiographic measurement grading system
Published Date	2021-07-15
Publication Title	International Journal of Environmental Research and Public Health
Volume	volume18
Issue	issue14
Publisher	MDPI
Start Page	7520
ISSN	1660-4601
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	34299970
DOI	10.3390/ijerph18147520
Web of Science KeyUT	000676598200001
Related Url	isVersionOf https://doi.org/10.3390/ijerph18147520

Short-term outcomes of mirogabalin in patients with peripheral neuropathic pain: a retrospective study

FullText URL	fulltext.pdf
Author	Tetsunaga, Tomoko\| Tetsunaga, Tomonori\| Nishida, Keiichiro\| Misawa, Haruo\| Takigawa, Tomoyuki\| Yamane, Kentaro\| Tsuji, Hironori\| Takei, Yoshitaka\| Ozaki, Toshifumi\|
Keywords	Peripheral neuropathic pain Mirogabalin Pregabalin Adverse event
Published Date	2020-05-26
Publication Title	Journal of Orthopaedic Surgery and Research
Volume	volume15
Issue	issue1
Publisher	Springer
Start Page	191
ISSN	1749-799X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	publisher
PubMed ID	32456647
DOI	10.1186/s13018-020-01709-3
Web of Science KeyUT	000538017400002
Related Url	isVersionOf https://doi.org/10.1186/s13018-020-01709-3

Induction of CEMIP in Chondrocytes by Inflammatory Cytokines: Underlying Mechanisms and Potential Involvement in Osteoarthritis

FullText URL	fulltext.pdf
Author	Ohtsuki, Takashi\| Hatipoglu, Omer F.\| Asano, Keiichi\| Inagaki, Junko\| Nishida, Keiichiro\| Hirohata, Satoshi\|
Keywords	cell migration-inducing hyaluronidase 1 (CEMIP) chondrocyte hyaluronan mechanical strain nuclear factor kappa B (NF-kappa B) osteoarthritis
Published Date	2020-04-29
Publication Title	International Journal of Molecular Sciences
Volume	volume21
Issue	issue9
Publisher	MDPI
Start Page	3140
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	32365591
DOI	10.3390/ijms21093140
Web of Science KeyUT	000535581700111
Related Url	isVersionOf https://doi.org/10.3390/ijms21093140

Differences between the root and horn cells of the human medial meniscus from the osteoarthritic knee in cellular characteristics and responses to mechanical stress

FullText URL	JOS_015_Fulltext.pdf JOS_015_Figures.pptx
Author	Okazaki, Yuki\| Furumatsu, Takayuki\| Kamatsuki, Yusuke\| Nishida, Keiichiro\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Saito, Taichi\| Ozaki, Toshifumi\|
Published Date	2020-03-26
Publication Title	Journal of Orthopaedic Science
Volume	volume26
Issue	issue2
Publisher	Elsevier
Start Page	230
End Page	236
ISSN	09492658
NCID	AA11052566
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Japanese Orthopaedic Association.
File Version	author
PubMed ID	32223991
DOI	10.1016/j.jos.2020.02.015
Related Url	isVersionOf https://doi.org/10.1016/j.jos.2020.02.015

Idiopathic Chondrolysis of the Hip Treated by Immunosuppressive Therapy and Arthroscopic Intervention

JaLCDOI	10.18926/AMO/57957
FullText URL	74_1_77.pdf
Author	Endo, Hirosuke\| Akazawa, Hirofumi\| Yashiro, Masato\| Yamada, Kazuki\| Sanki, Tomoaki\| Tetsunaga, Tomonori\| Nishida, Keiichiro\| Furumatsu, Takayuki\| Ozaki, Toshifumi\|
Abstract	Idiopathic chondrolysis of the hip (ICH), a very rare disorder of unknown etiology, occurs mainly in female adolescents. Characterized by pain, limp, stiffness and radiological narrowing joint space from the rapid destruction of the articular cartilage, ICH sometimes results in ankyloses. We present the case of a 10-year-old girl diagnosed with ICH based on arthroscopic inspection and synovium biopsy. The femoral deformity appeared gradually, like a cam-type femoroacetabular impingement. She was treated with intensive rehabilitation and immunosuppressive drug. We later performed an arthroscopic bumpectomy for residual symptoms. She achieved a favorable outcome as a 15-year-old at the latest follow-up.
Keywords	idiopathic chondrolysis hip joint medication bump arthroscopy
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2020-02
Volume	volume74
Issue	issue1
Publisher	Okayama University Medical School
Start Page	77
End Page	81
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2020 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	32099253
Web of Science KeyUT	000516606200012
NAID	120006795624

Two Cases of High Tibial Osteotomy in Patients with Rheumatoid Arthritis Treated with Biologic Disease-modifying Anti-rheumatic Drugs

JaLCDOI	10.18926/AMO/57720
FullText URL	73_6_537.pdf
Author	Takahara, Yasuhiro\| Nishida, Keiichiro\| Nakashima, Hirotaka\| Ochi, Nobuaki\| Uchida, Yoichiro\| Kato, Hisayoshi\| Itani, Satoru\| Nakamura, Makoto\| Iwasaki, Yuichi\| Tsujimura, Yoshitaka\|
Abstract	High tibial osteotomy (HTO) procedure is generally contraindicated in rheumatoid arthritis (RA) patients because synovial inflammation may exacerbate joint damage post-surgery. The natural course of joint destruction in RA changed dramatically with new treatment strategies and the introduction of biologic disease-modifying anti-rheumatic drugs (bDMARDs). We report the cases of two RA patients who underwent HTO and whose disease activities were well controlled by bDMARDs. Despite their short follow-up periods, they showed acceptable objective and subjective clinical results. We believe that the combination of bDMARDs and HTO can be indicated for selected RA patients before total knee arthroplasty.
Keywords	high tibial osteotomy rheumatoid arthritis biologic DMARD knee surgery
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2019-12
Volume	volume73
Issue	issue6
Publisher	Okayama University Medical School
Start Page	537
End Page	542
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2019 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	31871338
Web of Science KeyUT	000503431400011

Mechanical strain attenuates cytokine-induced ADAMTS9 expression via transient receptor potential vanilloid type 1

FullText URL	fulltext.pdf
Author	Ohtsuki, Takashi\| Shinaoka, Akira\| Kumagishi-Shinaoka, Kanae\| Asano, Keiichi\| Hatipoglu, Omer Faruk\| Inagaki, Junko\| Takahashi, Ken\| Oohashi, Toshitaka\| Nishida, Keiichiro\| Naruse, Keiji\| Hirohata, Satoshi\|
Published Date	2019-10-15
Publication Title	Experimental Cell Research
Volume	volume383
Issue	issue2
Publisher	Elsevier
Start Page	111556
ISSN	00144827
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 The Authors. Published by Elsevier Inc.
File Version	publisher
PubMed ID	31415758
DOI	10.1016/j.yexcr.2019.111556
Web of Science KeyUT	000488145400017
Related Url	isVersionOf https://doi.org/10.1016/j.yexcr.2019.111556