JaLCDOI 10.18926/AMO/68645
FullText URL 79_2_075.pdf
Author Higaki, Fumiyo| Morimitsu, Yusuke| Iguchi, Toshihiro| Hwang, Sung Il| Kitayama, Takahiro| Takahashi, Yuka| Uka, Mayu| Akagi, Noriaki| Sugaya, Akiko| Mitsuhashi, Toshiharu| Matsui, Yusuke| Hiraki, Takao|
Abstract Temporal bone computed tomography (CT) is frequently performed for pediatric patients with ear diseases. Advances in CT technology have improved diagnostic imaging quality, but reduction of radiation exposure remains a goal. We evaluated the potential for radiation dose reduction in temporal bone CT examinations using porcine ear ossicles and a photon-counting detector CT system. Three scans of the bilateral temporal bone were performed on each of three pig cadaver heads. In each of seven successive imaging sessions, the radiation dose was reduced by an additional one-seventh of the recommended dose (RD). Two board-certified radiologists independently scored the resulting images on a scale of 1 to 5 points, where 5 represented the image quality at the RD. Images scoring ≥4.5 points were considered acceptable. Noise was assessed in a 2-cm-diameter region near the ear ossicles, and standard deviation was measured for each of the seven decrements from the RD. As the radiation dose decreased, the noise progressively increased, and visual assessment scores progressively decreased. Acceptable image scores were obtained at six-sevenths (4.9), five-sevenths (4.8), four-sevenths (4.7), and three-sevenths (4.6) of the RD. Thus, acceptable porcine temporal bone CT images were obtained with a radiation dose reduction of approximately 50%.
Keywords computed tomography photon-counting detector computed tomography ear ossicle energy-integrating detector computed tomography
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 75
End Page 80
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
FullText URL fulltext.pdf
Author Fujii, Yuki| Matsumoto, Kazuyuki| Matsumi, Akihiro| Miyamoto, Kazuya| Uchida, Daisuke| Horiguchi, Shigeru| Tsutsumi, Koichiro| Mitsuhashi, Toshiharu| Otsuka, Motoyuki|
Keywords adverse events balloon-assisted ERCP benzodiazepine sedation
Published Date 2025-03-27
Publication Title Journal of Clinical Medicine
Volume volume14
Issue issue7
Publisher MDPI
Start Page 2287
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 by the authors.
File Version publisher
PubMed ID 40217737
DOI 10.3390/jcm14072287
Web of Science KeyUT 001463583200001
Related Url isVersionOf https://doi.org/10.3390/jcm14072287
FullText URL fulltext.pdf
Author Kitamura, Wataru| Fujii, Keiko| Tsuge, Mitsuru| Mitsuhashi, Toshiharu| Kobayashi, Hiroki| Kamoi, Chihiro| Yamamoto, Akira| Kondo, Takumi| Seike, Keisuke| Fujiwara, Hideaki| Asada, Noboru| Ennishi, Daisuke| Matsuoka, Ken-ichi| Fujii, Nobuharu| Maeda, Yoshinobu|
Keywords Allogeneic hematopoietic stem cell transplantation Graft-versus-host disease Teprenone Oxidative stress Interleukin-33
Note The version of record of this article, first published in Annals of Hematology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00277-025-06269-2|
Published Date 2025-02-24
Publication Title Annals of Hematology
Publisher Springer Science and Business Media LLC
ISSN 0939-5555
NCID AA1079712X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 39994018
DOI 10.1007/s00277-025-06269-2
Web of Science KeyUT 001429419900001
Related Url isVersionOf https://doi.org/10.1007/s00277-025-06269-2
FullText URL fulltext.pdf
Author Nakamura, Naoko| Mitsuhashi, Toshiharu| Nakashima, Yasuko| Matsumoto, Naomi| Yorifuji, Takashi|
Keywords community health planning diagnostic screening programmes home visits postpartum depression postnatal care quasi-experimental study
Published Date 2023-07-19
Publication Title Family Practice
Publisher Oxford University Press (OUP)
Start Page cmad074
ISSN 1460-2229
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37467366
DOI 10.1093/fampra/cmad074
Web of Science KeyUT 001030159100001
Related Url isVersionOf https://doi.org/10.1093/fampra/cmad074
FullText URL fulltext.pdf
Author Matsumoto, Naomi| Mitsui, Takashi| Kadowaki, Tomoka| Mitsuhashi, Toshiharu| Hirota, Tomoya| Masuyama, Hisashi| Yorifuji, Takashi|
Keywords In vitro fertilization (IVF) Assisted reproductive technology (ART) Long-term outcome Development
Published Date 2024-11-18
Publication Title European Journal of Pediatrics
Volume volume184
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 24
ISSN 1432-1076
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39557744
DOI 10.1007/s00431-024-05883-y
Web of Science KeyUT 001363062300001
Related Url isVersionOf https://doi.org/10.1007/s00431-024-05883-y
FullText URL fulltext.pdf
Author Matsumoto, Naomi| Mitsuhashi, Toshiharu| Matsuo, Rumi| Kadowaki, Tomoka| Takao, Soshi| Yorifuji, Takashi|
Keywords COVID-19 Vaccine Omicron Prevention Pneumonia
Published Date 2023
Publication Title JMA Journal
Volume volume6
Issue issue4
Publisher Japan Medical Association
Start Page 463
End Page 469
ISSN 2433-3298
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Japan Medical Association
File Version publisher
PubMed ID 37941689
DOI 10.31662/jmaj.2023-0019
Web of Science KeyUT 001117541000004
Related Url isVersionOf https://doi.org/10.31662/jmaj.2023-0019
Author Matsumoto, Naomi| Sasaki, Ayako| Kadowaki, Tomoka| Mitsuhashi, Toshiharu| Takao, Soshi| Yorifuji, Takashi|
Keywords SARS-CoV-2 Vaccine Antibody Mixed-effects model Omicron
Note © 2024 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Aug. 2025.|
Published Date 2024-08
Publication Title Vaccine
Volume volume42
Issue issue21
Publisher Elsevier BV
Start Page 126156
ISSN 0264-410X
NCID AA10491877
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Elsevier Ltd.
File Version author
PubMed ID 39088986
DOI 10.1016/j.vaccine.2024.126156
Web of Science KeyUT 001285745600001
Related Url isVersionOf https://doi.org/10.1016/j.vaccine.2024.126156
FullText URL fulltext.pdf
Author Tsuge, Mitsuru| Ichihara, Eiki| Hasegawa, Kou| Kudo, Kenichiro| Tanimoto, Yasushi| Nouso, Kazuhiro| Oda, Naohiro| Mitsumune, Sho| Kimura, Goro| Yamada, Haruto| Takata, Ichiro| Mitsuhashi, Toshiharu| Taniguchi, Akihiko| Tsukahara, Kohei| Aokage, Toshiyuki| Hagiya, Hideharu| Toyooka, Shinichi| Tsukahara, Hirokazu| Maeda, Yoshinobu|
Keywords novel coronavirus disease 2019 pneumonia hydroperoxide nitric oxide reactive oxygen species citrulline arginine asymmetric dimethylarginine
Published Date 2024-07-31
Publication Title International Journal of Molecular Sciences
Volume volume25
Issue issue15
Publisher MDPI
Start Page 8370
ISSN 1661-6596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 39125944
DOI 10.3390/ijms25158370
Web of Science KeyUT 001286890700001
Related Url isVersionOf https://doi.org/10.3390/ijms25158370
FullText URL fulltext.pdf
Author Sakamoto, Yoko| Mitsuhashi, Toshiharu| Hotta, Katsuyuki|
Keywords attitude end-of-life care older persons decision making percutaneous endoscopic gastrostomy tube feeding
Published Date 2024-07-08
Publication Title Palliative Medicine Reports
Volume volume5
Issue issue1
Publisher Mary Ann Liebert
Start Page 206
End Page 214
ISSN 2689-2820
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Yoko Sakamoto et al., 2024
File Version publisher
DOI 10.1089/pmr.2023.0088
Web of Science KeyUT 001264185700001
Related Url isVersionOf https://doi.org/10.1089/pmr.2023.0088
FullText URL fulltext.pdf
Author Mitsuhashi, Toshiharu|
Keywords COVID-19 Metabolic syndrome Healch check up Conditional average treatment effect CATE Public health Pandemic
Published Date 2024-04-05
Publication Title PeerJ
Volume volume12
Publisher PeerJ
Start Page e17013
ISSN 2167-8359
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Mitsuhashi
File Version publisher
PubMed ID 38590703
DOI 10.7717/peerj.17013
Web of Science KeyUT 001203244800004
Related Url isVersionOf https://doi.org/10.7717/peerj.17013
FullText URL fulltext.pdf
Author Iguchi, Toshihiro| Matsui, Yusuke| Toji, Tomohiro| Sakurai, Jun| Tomita, Koji| Uka, Mayu| Umakoshi, Noriyuki| Kawabata, Takahiro| Munetomo, Kazuaki| Mitsuhashi, Toshiharu| Hiraki, Takao|
Keywords Biopsy Kidney Tumor Computed tomography Ultrasound
Note The version of record of this article, first published in Japanese Journal of Radiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11604-023-01496-x|
Published Date 2023-10-14
Publication Title Japanese Journal of Radiology
Volume volume42
Issue issue3
Publisher Springer Science and Business Media LLC
Start Page 319
End Page 325
ISSN 1867-1071
NCID AA12375935
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37833443
DOI 10.1007/s11604-023-01496-x
Web of Science KeyUT 001086535200001
Related Url isVersionOf https://doi.org/10.1007/s11604-023-01496-x
JaLCDOI 10.18926/AMO/66916
FullText URL 78_2_135.pdf
Author Higaki, Fumiyo| Morimitsu, Yusuke| Iguchi, Toshihiro| Saito, Hayato| Takaki, Haruhiko| Nakagoshi, Ayako| Wada, Maki| Uka, Mayu| Akagi, Noriaki| Mitsuhashi, Toshiharu| Matsui, Yusuke| Hiraki, Takao|
Abstract This study aimed to evaluate the potential reduction in contrast medium utilization using photon-counting detector computed tomography (PCD-CT). One PCD-CT scan (CT1) and three conventional (non-PCD-CT) CT scans (CT2-CT4) were performed using a multi-energy CT phantom that contained eight rods with different iodine concentrations (0.2, 0.5, 1, 2, 5, 10, 15, and 20 mg/ml). The CT values of the seven groups (CT1 for 40, 50, 60, and 70 keV; and CT2-4) were measured. Noise and contrast-to-noise ratio (CNR) were assessed for the eight rods at various iodine concentrations. CT2 and CT1 (40 keV) respectively required 20 mg/ml and 5 mg/ml of iodine, indicating that a comparable contrast effect could be obtained with approximately one-fourth of the contrast medium amount. The standard deviation values increased at lower energy levels irrespective of the iodine concentration. The CNR exhibited a decreasing trend with lower iodine concentrations, while it remained relatively stable across all iodine levels (40-70 keV). This study demonstrated that virtual monochromatic 40 keV images offer a similar contrast effect with a reduced contrast medium amount when compared to conventional CT systems at 120 kV.
Keywords photon-counting detector CT energy integrating detector CT computed tomography contrast medium amount reduction
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 135
End Page 142
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688831
Web of Science KeyUT 001229151800005
FullText URL fulltext.pdf
Author Matsumoto, Naomi| Sasaki, Ayako| Kadowaki, Tomoka| Mitsuhashi, Toshiharu| Takao, Soshi| Yorifuji, Takashi|
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-55245-9|
Published Date 2024-02-25
Publication Title Scientific Reports
Volume volume14
Issue issue1
Publisher Nature Portfolio
Start Page 4564
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38403650
DOI 10.1038/s41598-024-55245-9
Web of Science KeyUT 001177180300006
Related Url isVersionOf https://doi.org/10.1038/s41598-024-55245-9
FullText URL fulltext.pdf
Author Kuroda, Shinji| Ishida, Michihiro| Choda, Yasuhiro| Muraoka, Atsushi| Hato, Shinji| Kagawa, Tetsuya| Tanaka, Norimitsu| Mitsuhashi, Toshiharu| Kakiuchi, Yoshihiko| Kikuchi, Satoru| Nishizaki, Masahiko| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Keywords anti-reflux surgery double-flap technique gastric cancer Kamikawa procedure proximal gastrectomy
Published Date 2024-02-22
Publication Title Annals of Gastroenterological Surgery
Volume volume8
Issue issue3
Publisher Wiley
Start Page 374
End Page 382
ISSN 2475-0328
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Authors.
File Version publisher
PubMed ID 38707222
DOI 10.1002/ags3.12783
Web of Science KeyUT 001174392500001
Related Url isVersionOf https://doi.org/10.1002/ags3.12783
FullText URL fulltext.pdf
Author Nakamura, Naoko| Mitsuhashi, Toshiharu| Matsumoto, Naomi| Hayase, Shunsaku| Yorifuji, Takashi|
Keywords antihypertensive agents COVID-19 health behavior interrupted time series analysis prescription drugs treatment interruption
Published Date 2024-02-21
Publication Title Journal of General and Family Medicine
Volume volume25
Issue issue2
Publisher Wiley
Start Page 102
End Page 109
ISSN 2189-7948
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Authors.
File Version publisher
PubMed ID 38481745
DOI 10.1002/jgf2.678
Web of Science KeyUT 001168139300001
Related Url isVersionOf https://doi.org/10.1002/jgf2.678
FullText URL fulltext.pdf
Author Kikuchi, Satoru| Matsusaki, Takashi| Mitsuhashi, Toshiharu| Kuroda, Shinji| Kashima, Hajime| Takata, Nobuo| Mitsui, Ema| Kakiuchi, Yoshihiko| Noma, Kazuhiro| Umeda, Yuzo| Morimatsu, Hiroshi| Fujiwara, Toshiyoshi|
Published Date 2024-01-18
Publication Title BJS Open
Volume volume8
Issue issue1
Publisher Oxford University Press
Start Page zrad161
ISSN 2474-9842
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38242571
DOI 10.1093/bjsopen/zrad161
Web of Science KeyUT 001148373800007
Related Url isVersionOf https://doi.org/10.1093/bjsopen/zrad161
JaLCDOI 10.18926/AMO/66152
FullText URL 77_6_607.pdf
Author Tani, Yasunari| Kashima, Saori| Mitsuhashi, Toshiharu| Suzuki, Etsuji| Takao, Soshi| Yorifuji, Takashi|
Abstract Many studies have shown an association between long-term exposure to particulate matter having an aerodynamic diameter of 2.5 μm or less (PM2.5) and diabetes mellitus (DM), but few studies have focused on Asian subjects. We thus examined the association between long-term exposure to PM2.5 and DM prevalence in Okayama City, Japan. We included 76,591 participants who had received basic health checkups in 2006 and 2007. We assigned the census-level modeled PM2.5 data from 2006 and 2007 to each participant and defined DM using treatment status and the blood testing. PM2.5 was associated with DM prevalence, and the prevalence ratio (95% confidence interval) was 1.10 (1.00-1.20) following each interquartile range increase (2.1 μg/m3) in PM2.5. This finding is consistent with previous results and suggests that long-term exposure to PM2.5 is associated with an increased prevalence of DM in Okayama City, Japan, where the PM2.5 level is lower than in other cities in Asian countries.
Keywords air pollution diabetes mellitus epidemiology glycosylated hemoglobin particulate matter
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 607
End Page 612
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145934
Web of Science KeyUT 001164631200005
JaLCDOI 10.18926/AMO/66148
FullText URL 77_6_567.pdf
Author Matsumoto, Naomi| Higuchi, Chigusa| Miyaji, Chikara| Mitsuhashi, Toshiharu| Hagiya, Hideharu| Takao, Soshi| Yorifuji, Takashi|
Abstract This paper presents the results of a series of surveys conducted from July 2021 to March 2023 to investigate the post-vaccination adverse reactions to the mRNA-1273 (Moderna) vaccine among faculty, staff, and students at Okayama University. These studies complement the official surveys conducted by the Ministry of Health, Labour and Welfare (MHLW) and provide a more representative picture of adverse reactions in the general population including large numbers of healthy young people. Pain, swelling, redness at the injection site, fever, headache, and malaise were the main adverse reactions reported. The proportion of adverse reactions was generally higher after the second vaccination and decreased with each additional vaccination. No statistically significant differences in the adverse reactions were found for males and females and those with/without a history of allergy, but a lower proportion of fever was observed in older participants and those with underlying medical conditions. We also evaluated the association between adverse reactions and antibody titers after the third vaccination and found no significant differences in antibody levels one month after vaccination. This series of studies highlights the importance of conducting surveys in diverse populations to provide a more representative picture of post-vaccination adverse reactions during a pandemic.
Keywords coronavirus disease 2019 adverse reactions mRNA vaccine antibody titers young adults
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 567
End Page 575
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145930
Web of Science KeyUT 001164631200001
FullText URL fulltext.pdf
Author Ichihara, Eiki| Hasegawa, Kou| Kudo, Kenichiro| Tanimoto, Yasushi| Nouso, Kazuhiro| Oda, Naohiro| Mitsumune, Sho| Yamada, Haruto| Takata, Ichiro| Hagiya, Hideharu| Mitsuhashi, Toshiharu| Taniguchi, Akihiko| Toyooka, Shinichi| Tsukahara, Kohei| Aokage, Toshiyuki| Tsukahara, Hirokazu| Kiura, Katsuyuki| Maeda, Yoshinobu|
Published Date 2023-10-26
Publication Title PLoS ONE
Volume volume18
Issue issue10
Publisher Public Library of Science
Start Page e0287501
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Ichihara et al.
File Version publisher
PubMed ID 37883347
DOI 10.1371/journal.pone.0287501
Web of Science KeyUT 001094123400028
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0287501
FullText URL fulltext.pdf
Author Toyosawa, Junki| Yamasaki, Yasushi| Fujimoto, Tsuyoshi| Tanaka, Shouichi| Tanaka, Takehiro| Mitsuhashi, Toshiharu| Okada, Hiroyuki|
Published Date 2022-05-13
Publication Title Endoscopy International Open
Volume volume10
Issue issue05
Publisher Georg Thieme Verlag KG
Start Page E602
End Page E608
ISSN 2364-3722
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022. The Author(s).
File Version publisher
PubMed ID 35571476
DOI 10.1055/a-1785-8616
Web of Science KeyUT 000794976400009
Related Url isVersionOf https://doi.org/10.1055/a-1785-8616