三橋利晴

Novel method of leukocytapheresis using a highly concentrated sodium citrate solution alternative to acid citrate dextrose solution A

フルテキストURL	fulltext.pdf
著者	Abe, Masaya\| Fujii, Keiko\| Mitsuhashi, Toshiharu\| Kitamura, Wataru\| Ikeuchi, Kazuhiro\| Fukumi, Takuya\| Washio, Kana\| Otsuka, Fumio\| Maeda, Yoshinobu\| Fujii, Nobuharu\|
キーワード	anticoagulant apheresis high sodium citrate concentration Spectra Optia
発行日	2025-05-19
出版物タイトル	Transfusion
出版者	Wiley
ISSN	0041-1132
NCID	AA00868753
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Author(s).
論文のバージョン	publisher
PubMed ID	40387021
DOI	10.1111/trf.18280
Web of Science KeyUT	001490160900001
関連URL	isVersionOf https://doi.org/10.1111/trf.18280

Efficient diagnosis for endoscopic remission in Crohn's diseases by the combination of three non-invasive markers

フルテキストURL	fulltext.pdf
著者	Takei, Kensuke\| Inokuchi, Toshihiro\| Hiraoka, Sakiko\| Ishiguro, Mikako\| Toyosawa, Junki\| Aoyama, Yuki\| Igawa, Shoko\| Takeuchi, Keiko\| Yamasaki, Yasushi\| Kinugasa, Hideaki\| Takahara, Masahiro\| Kawano, Seiji\| Mitsuhashi, Toshiharu\| Otsuka, Motoyuki\|
キーワード	CD, Crohn's disease LRG, Leucine-rich alpha-2 glycoprotein Fcal, Fecal calprotectin CRP, C-reactive protein ER, Endoscopic remission
発行日	2025-05-13
出版物タイトル	BMC Gastroenterology
巻	25巻
号	1号
出版者	BMC
開始ページ	364
ISSN	1471-230X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025.
論文のバージョン	publisher
PubMed ID	40355822
DOI	10.1186/s12876-025-03880-5
Web of Science KeyUT	001488265300002
関連URL	isVersionOf https://doi.org/10.1186/s12876-025-03880-5

Potential for Radiation Dose Reduction in Temporal Bone CT Imaging Using Photon-Counting Detector CT

JaLCDOI	10.18926/AMO/68645
フルテキストURL	79_2_075.pdf
著者	Higaki, Fumiyo\| Morimitsu, Yusuke\| Iguchi, Toshihiro\| Hwang, Sung Il\| Kitayama, Takahiro\| Takahashi, Yuka\| Uka, Mayu\| Akagi, Noriaki\| Sugaya, Akiko\| Mitsuhashi, Toshiharu\| Matsui, Yusuke\| Hiraki, Takao\|
抄録	Temporal bone computed tomography (CT) is frequently performed for pediatric patients with ear diseases. Advances in CT technology have improved diagnostic imaging quality, but reduction of radiation exposure remains a goal. We evaluated the potential for radiation dose reduction in temporal bone CT examinations using porcine ear ossicles and a photon-counting detector CT system. Three scans of the bilateral temporal bone were performed on each of three pig cadaver heads. In each of seven successive imaging sessions, the radiation dose was reduced by an additional one-seventh of the recommended dose (RD). Two board-certified radiologists independently scored the resulting images on a scale of 1 to 5 points, where 5 represented the image quality at the RD. Images scoring ≥4.5 points were considered acceptable. Noise was assessed in a 2-cm-diameter region near the ear ossicles, and standard deviation was measured for each of the seven decrements from the RD. As the radiation dose decreased, the noise progressively increased, and visual assessment scores progressively decreased. Acceptable image scores were obtained at six-sevenths (4.9), five-sevenths (4.8), four-sevenths (4.7), and three-sevenths (4.6) of the RD. Thus, acceptable porcine temporal bone CT images were obtained with a radiation dose reduction of approximately 50%.
キーワード	computed tomography photon-counting detector computed tomography ear ossicle energy-integrating detector computed tomography
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-04
巻	79巻
号	2号
出版者	Okayama University Medical School
開始ページ	75
終了ページ	80
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40302278
Web of Science KeyUT	001485544200002

Comparison of Midazolam and Diazepam for Sedation in Patients Undergoing Double-Balloon Endoscopic Retrograde Cholangiopancreatography: A Propensity Score-Matched Analysis

フルテキストURL	fulltext.pdf
著者	Fujii, Yuki\| Matsumoto, Kazuyuki\| Matsumi, Akihiro\| Miyamoto, Kazuya\| Uchida, Daisuke\| Horiguchi, Shigeru\| Tsutsumi, Koichiro\| Mitsuhashi, Toshiharu\| Otsuka, Motoyuki\|
キーワード	adverse events balloon-assisted ERCP benzodiazepine sedation
発行日	2025-03-27
出版物タイトル	Journal of Clinical Medicine
巻	14巻
号	7号
出版者	MDPI
開始ページ	2287
ISSN	2077-0383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 by the authors.
論文のバージョン	publisher
PubMed ID	40217737
DOI	10.3390/jcm14072287
Web of Science KeyUT	001463583200001
関連URL	isVersionOf https://doi.org/10.3390/jcm14072287

A randomized controlled trial of conventional GVHD prophylaxis with or without teprenone for the prevention of severe acute GVHD

フルテキストURL	fulltext.pdf
著者	Kitamura, Wataru\| Fujii, Keiko\| Tsuge, Mitsuru\| Mitsuhashi, Toshiharu\| Kobayashi, Hiroki\| Kamoi, Chihiro\| Yamamoto, Akira\| Kondo, Takumi\| Seike, Keisuke\| Fujiwara, Hideaki\| Asada, Noboru\| Ennishi, Daisuke\| Matsuoka, Ken-ichi\| Fujii, Nobuharu\| Maeda, Yoshinobu\|
キーワード	Allogeneic hematopoietic stem cell transplantation Graft-versus-host disease Teprenone Oxidative stress Interleukin-33
備考	The version of record of this article, first published in Annals of Hematology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00277-025-06269-2\|
発行日	2025-02-24
出版物タイトル	Annals of Hematology
出版者	Springer Science and Business Media LLC
ISSN	0939-5555
NCID	AA1079712X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	39994018
DOI	10.1007/s00277-025-06269-2
Web of Science KeyUT	001429419900001
関連URL	isVersionOf https://doi.org/10.1007/s00277-025-06269-2

Effect of 2-week postpartum check-ups on screening positive for postpartum depression: a population-based cohort study using instrumental variable estimation in Japan

フルテキストURL	fulltext.pdf
著者	Nakamura, Naoko\| Mitsuhashi, Toshiharu\| Nakashima, Yasuko\| Matsumoto, Naomi\| Yorifuji, Takashi\|
キーワード	community health planning diagnostic screening programmes home visits postpartum depression postnatal care quasi-experimental study
発行日	2023-07-19
出版物タイトル	Family Practice
出版者	Oxford University Press (OUP)
開始ページ	cmad074
ISSN	1460-2229
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023.
論文のバージョン	publisher
PubMed ID	37467366
DOI	10.1093/fampra/cmad074
Web of Science KeyUT	001030159100001
関連URL	isVersionOf https://doi.org/10.1093/fampra/cmad074

In vitro fertilization and long-term child health and development: nationwide birth cohort study in Japan

フルテキストURL	fulltext.pdf
著者	Matsumoto, Naomi\| Mitsui, Takashi\| Kadowaki, Tomoka\| Mitsuhashi, Toshiharu\| Hirota, Tomoya\| Masuyama, Hisashi\| Yorifuji, Takashi\|
キーワード	In vitro fertilization (IVF) Assisted reproductive technology (ART) Long-term outcome Development
発行日	2024-11-18
出版物タイトル	European Journal of Pediatrics
巻	184巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	24
ISSN	1432-1076
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	39557744
DOI	10.1007/s00431-024-05883-y
Web of Science KeyUT	001363062300001
関連URL	isVersionOf https://doi.org/10.1007/s00431-024-05883-y

Effectiveness of the Original COVID-19 Vaccine against COVID-19 Exacerbations during the Omicron Wave: A Population-based Study in Okayama, Japan

フルテキストURL	fulltext.pdf
著者	Matsumoto, Naomi\| Mitsuhashi, Toshiharu\| Matsuo, Rumi\| Kadowaki, Tomoka\| Takao, Soshi\| Yorifuji, Takashi\|
キーワード	COVID-19 Vaccine Omicron Prevention Pneumonia
発行日	2023
出版物タイトル	JMA Journal
巻	6巻
号	4号
出版者	Japan Medical Association
開始ページ	463
終了ページ	469
ISSN	2433-3298
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Japan Medical Association
論文のバージョン	publisher
PubMed ID	37941689
DOI	10.31662/jmaj.2023-0019
Web of Science KeyUT	001117541000004
関連URL	isVersionOf https://doi.org/10.31662/jmaj.2023-0019

Kinetics of SARS-CoV-2 antibody titers after booster vaccinations during an Omicron surge in Japan

著者	Matsumoto, Naomi\| Sasaki, Ayako\| Kadowaki, Tomoka\| Mitsuhashi, Toshiharu\| Takao, Soshi\| Yorifuji, Takashi\|
キーワード	SARS-CoV-2 Vaccine Antibody Mixed-effects model Omicron
備考	© 2024 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/\| This fulltext file will be available in Aug. 2025.\|
発行日	2024-08
出版物タイトル	Vaccine
巻	42巻
号	21号
出版者	Elsevier BV
開始ページ	126156
ISSN	0264-410X
NCID	AA10491877
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 Elsevier Ltd.
論文のバージョン	author
PubMed ID	39088986
DOI	10.1016/j.vaccine.2024.126156
Web of Science KeyUT	001285745600001
関連URL	isVersionOf https://doi.org/10.1016/j.vaccine.2024.126156

Increased Oxidative Stress and Decreased Citrulline in Blood Associated with Severe Novel Coronavirus Pneumonia in Adult Patients

フルテキストURL	fulltext.pdf
著者	Tsuge, Mitsuru\| Ichihara, Eiki\| Hasegawa, Kou\| Kudo, Kenichiro\| Tanimoto, Yasushi\| Nouso, Kazuhiro\| Oda, Naohiro\| Mitsumune, Sho\| Kimura, Goro\| Yamada, Haruto\| Takata, Ichiro\| Mitsuhashi, Toshiharu\| Taniguchi, Akihiko\| Tsukahara, Kohei\| Aokage, Toshiyuki\| Hagiya, Hideharu\| Toyooka, Shinichi\| Tsukahara, Hirokazu\| Maeda, Yoshinobu\|
キーワード	novel coronavirus disease 2019 pneumonia hydroperoxide nitric oxide reactive oxygen species citrulline arginine asymmetric dimethylarginine
発行日	2024-07-31
出版物タイトル	International Journal of Molecular Sciences
巻	25巻
号	15号
出版者	MDPI
開始ページ	8370
ISSN	1661-6596
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 by the authors.
論文のバージョン	publisher
PubMed ID	39125944
DOI	10.3390/ijms25158370
Web of Science KeyUT	001286890700001
関連URL	isVersionOf https://doi.org/10.3390/ijms25158370

Factors Associated with Differences in Physicians’ Attitudes toward Percutaneous Endoscopic Gastrostomy Feeding in Older Adults Receiving End-of-Life Care in Japan: A Cross-Sectional Study

フルテキストURL	fulltext.pdf
著者	Sakamoto, Yoko\| Mitsuhashi, Toshiharu\| Hotta, Katsuyuki\|
キーワード	attitude end-of-life care older persons decision making percutaneous endoscopic gastrostomy tube feeding
発行日	2024-07-08
出版物タイトル	Palliative Medicine Reports
巻	5巻
号	1号
出版者	Mary Ann Liebert
開始ページ	206
終了ページ	214
ISSN	2689-2820
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Yoko Sakamoto et al., 2024
論文のバージョン	publisher
DOI	10.1089/pmr.2023.0088
Web of Science KeyUT	001264185700001
関連URL	isVersionOf https://doi.org/10.1089/pmr.2023.0088

Heterogeneity of the effect of the COVID-19 pandemic on the incidence of Metabolic Syndrome onset at a Japanese campus

フルテキストURL	fulltext.pdf
著者	Mitsuhashi, Toshiharu\|
キーワード	COVID-19 Metabolic syndrome Healch check up Conditional average treatment effect CATE Public health Pandemic
発行日	2024-04-05
出版物タイトル	PeerJ
巻	12巻
出版者	PeerJ
開始ページ	e17013
ISSN	2167-8359
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 Mitsuhashi
論文のバージョン	publisher
PubMed ID	38590703
DOI	10.7717/peerj.17013
Web of Science KeyUT	001203244800004
関連URL	isVersionOf https://doi.org/10.7717/peerj.17013

Prospective evaluation of core number of biopsy for renal tumor: are multiple cores preferable?

フルテキストURL	fulltext.pdf
著者	Iguchi, Toshihiro\| Matsui, Yusuke\| Toji, Tomohiro\| Sakurai, Jun\| Tomita, Koji\| Uka, Mayu\| Umakoshi, Noriyuki\| Kawabata, Takahiro\| Munetomo, Kazuaki\| Mitsuhashi, Toshiharu\| Hiraki, Takao\|
キーワード	Biopsy Kidney Tumor Computed tomography Ultrasound
備考	The version of record of this article, first published in Japanese Journal of Radiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11604-023-01496-x\|
発行日	2023-10-14
出版物タイトル	Japanese Journal of Radiology
巻	42巻
号	3号
出版者	Springer Science and Business Media LLC
開始ページ	319
終了ページ	325
ISSN	1867-1071
NCID	AA12375935
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37833443
DOI	10.1007/s11604-023-01496-x
Web of Science KeyUT	001086535200001
関連URL	isVersionOf https://doi.org/10.1007/s11604-023-01496-x

Photon-Counting Detector CT: Potential for 75% Reduction in Contrast Medium Amount: A Phantom Study

JaLCDOI	10.18926/AMO/66916
フルテキストURL	78_2_135.pdf
著者	Higaki, Fumiyo\| Morimitsu, Yusuke\| Iguchi, Toshihiro\| Saito, Hayato\| Takaki, Haruhiko\| Nakagoshi, Ayako\| Wada, Maki\| Uka, Mayu\| Akagi, Noriaki\| Mitsuhashi, Toshiharu\| Matsui, Yusuke\| Hiraki, Takao\|
抄録	This study aimed to evaluate the potential reduction in contrast medium utilization using photon-counting detector computed tomography (PCD-CT). One PCD-CT scan (CT1) and three conventional (non-PCD-CT) CT scans (CT2-CT4) were performed using a multi-energy CT phantom that contained eight rods with different iodine concentrations (0.2, 0.5, 1, 2, 5, 10, 15, and 20 mg/ml). The CT values of the seven groups (CT1 for 40, 50, 60, and 70 keV; and CT2-4) were measured. Noise and contrast-to-noise ratio (CNR) were assessed for the eight rods at various iodine concentrations. CT2 and CT1 (40 keV) respectively required 20 mg/ml and 5 mg/ml of iodine, indicating that a comparable contrast effect could be obtained with approximately one-fourth of the contrast medium amount. The standard deviation values increased at lower energy levels irrespective of the iodine concentration. The CNR exhibited a decreasing trend with lower iodine concentrations, while it remained relatively stable across all iodine levels (40-70 keV). This study demonstrated that virtual monochromatic 40 keV images offer a similar contrast effect with a reduced contrast medium amount when compared to conventional CT systems at 120 kV.
キーワード	photon-counting detector CT energy integrating detector CT computed tomography contrast medium amount reduction
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	135
終了ページ	142
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688831
Web of Science KeyUT	001229151800005

Longitudinal antibody dynamics after COVID-19 vaccine boosters based on prior infection status and booster doses

フルテキストURL	fulltext.pdf
著者	Matsumoto, Naomi\| Sasaki, Ayako\| Kadowaki, Tomoka\| Mitsuhashi, Toshiharu\| Takao, Soshi\| Yorifuji, Takashi\|
備考	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-55245-9\|
発行日	2024-02-25
出版物タイトル	Scientific Reports
巻	14巻
号	1号
出版者	Nature Portfolio
開始ページ	4564
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	38403650
DOI	10.1038/s41598-024-55245-9
Web of Science KeyUT	001177180300006
関連URL	isVersionOf https://doi.org/10.1038/s41598-024-55245-9

A multi-center, prospective, clinical study to evaluate the anti-reflux efficacy of laparoscopic double-flap technique (lD-FLAP Study)

フルテキストURL	fulltext.pdf
著者	Kuroda, Shinji\| Ishida, Michihiro\| Choda, Yasuhiro\| Muraoka, Atsushi\| Hato, Shinji\| Kagawa, Tetsuya\| Tanaka, Norimitsu\| Mitsuhashi, Toshiharu\| Kakiuchi, Yoshihiko\| Kikuchi, Satoru\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
キーワード	anti-reflux surgery double-flap technique gastric cancer Kamikawa procedure proximal gastrectomy
発行日	2024-02-22
出版物タイトル	Annals of Gastroenterological Surgery
巻	8巻
号	3号
出版者	Wiley
開始ページ	374
終了ページ	382
ISSN	2475-0328
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 The Authors.
論文のバージョン	publisher
PubMed ID	38707222
DOI	10.1002/ags3.12783
Web of Science KeyUT	001174392500001
関連URL	isVersionOf https://doi.org/10.1002/ags3.12783

Treatment interruption in hypertensive patients during the COVID-19 pandemic: An interrupted time series analysis using prescription data in Okayama, Japan

フルテキストURL	fulltext.pdf
著者	Nakamura, Naoko\| Mitsuhashi, Toshiharu\| Matsumoto, Naomi\| Hayase, Shunsaku\| Yorifuji, Takashi\|
キーワード	antihypertensive agents COVID-19 health behavior interrupted time series analysis prescription drugs treatment interruption
発行日	2024-02-21
出版物タイトル	Journal of General and Family Medicine
巻	25巻
号	2号
出版者	Wiley
開始ページ	102
終了ページ	109
ISSN	2189-7948
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 The Authors.
論文のバージョン	publisher
PubMed ID	38481745
DOI	10.1002/jgf2.678
Web of Science KeyUT	001168139300001
関連URL	isVersionOf https://doi.org/10.1002/jgf2.678

Epidural versus patient-controlled intravenous analgesia on pain relief and recovery after laparoscopic gastrectomy for gastric cancer: randomized clinical trial

フルテキストURL	fulltext.pdf
著者	Kikuchi, Satoru\| Matsusaki, Takashi\| Mitsuhashi, Toshiharu\| Kuroda, Shinji\| Kashima, Hajime\| Takata, Nobuo\| Mitsui, Ema\| Kakiuchi, Yoshihiko\| Noma, Kazuhiro\| Umeda, Yuzo\| Morimatsu, Hiroshi\| Fujiwara, Toshiyoshi\|
発行日	2024-01-18
出版物タイトル	BJS Open
巻	8巻
号	1号
出版者	Oxford University Press
開始ページ	zrad161
ISSN	2474-9842
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024.
論文のバージョン	publisher
PubMed ID	38242571
DOI	10.1093/bjsopen/zrad161
Web of Science KeyUT	001148373800007
関連URL	isVersionOf https://doi.org/10.1093/bjsopen/zrad161

Fine Particulate Matter and Diabetes Prevalence in Okayama, Japan

JaLCDOI	10.18926/AMO/66152
フルテキストURL	77_6_607.pdf
著者	Tani, Yasunari\| Kashima, Saori\| Mitsuhashi, Toshiharu\| Suzuki, Etsuji\| Takao, Soshi\| Yorifuji, Takashi\|
抄録	Many studies have shown an association between long-term exposure to particulate matter having an aerodynamic diameter of 2.5 μm or less (PM2.5) and diabetes mellitus (DM), but few studies have focused on Asian subjects. We thus examined the association between long-term exposure to PM2.5 and DM prevalence in Okayama City, Japan. We included 76,591 participants who had received basic health checkups in 2006 and 2007. We assigned the census-level modeled PM2.5 data from 2006 and 2007 to each participant and defined DM using treatment status and the blood testing. PM2.5 was associated with DM prevalence, and the prevalence ratio (95% confidence interval) was 1.10 (1.00-1.20) following each interquartile range increase (2.1 μg/m3) in PM2.5. This finding is consistent with previous results and suggests that long-term exposure to PM2.5 is associated with an increased prevalence of DM in Okayama City, Japan, where the PM2.5 level is lower than in other cities in Asian countries.
キーワード	air pollution diabetes mellitus epidemiology glycosylated hemoglobin particulate matter
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-12
巻	77巻
号	6号
出版者	Okayama University Medical School
開始ページ	607
終了ページ	612
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38145934
Web of Science KeyUT	001164631200005

Review of a Series of Surveys on Adverse Reactions to the COVID-19 mRNA-1273 Vaccine at Okayama University

JaLCDOI	10.18926/AMO/66148
フルテキストURL	77_6_567.pdf
著者	Matsumoto, Naomi\| Higuchi, Chigusa\| Miyaji, Chikara\| Mitsuhashi, Toshiharu\| Hagiya, Hideharu\| Takao, Soshi\| Yorifuji, Takashi\|
抄録	This paper presents the results of a series of surveys conducted from July 2021 to March 2023 to investigate the post-vaccination adverse reactions to the mRNA-1273 (Moderna) vaccine among faculty, staff, and students at Okayama University. These studies complement the official surveys conducted by the Ministry of Health, Labour and Welfare (MHLW) and provide a more representative picture of adverse reactions in the general population including large numbers of healthy young people. Pain, swelling, redness at the injection site, fever, headache, and malaise were the main adverse reactions reported. The proportion of adverse reactions was generally higher after the second vaccination and decreased with each additional vaccination. No statistically significant differences in the adverse reactions were found for males and females and those with/without a history of allergy, but a lower proportion of fever was observed in older participants and those with underlying medical conditions. We also evaluated the association between adverse reactions and antibody titers after the third vaccination and found no significant differences in antibody levels one month after vaccination. This series of studies highlights the importance of conducting surveys in diverse populations to provide a more representative picture of post-vaccination adverse reactions during a pandemic.
キーワード	coronavirus disease 2019 adverse reactions mRNA vaccine antibody titers young adults
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2023-12
巻	77巻
号	6号
出版者	Okayama University Medical School
開始ページ	567
終了ページ	575
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38145930
Web of Science KeyUT	001164631200001

三橋 利晴