Miyahara, Nobuaki - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

The Roles of Neuropeptide Y in Respiratory Disease Pathogenesis via the Airway Immune Response

JaLCDOI	10.18926/AMO/66912
FullText URL	78_2_095.pdf
Author	Itano, Junko\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Miyahara, Nobuaki\|
Abstract	The lungs are very complex organs, and the respiratory system performs the dual roles of repairing tissue while protecting against infection from various environmental stimuli. Persistent external irritation disrupts the immune responses of tissues and cells in the respiratory system, ultimately leading to respiratory disease. Neuropeptide Y (NPY) is a 36-amino-acid polypeptide and a neurotransmitter that regulates homeostasis. The NPY receptor is a seven-transmembrane-domain G-protein-coupled receptor with six subtypes (Y1, Y2, Y3, Y4, Y5, and Y6). Of these receptors, Y1, Y2, Y4, and Y5 are functional in humans, and Y1 plays important roles in the immune responses of many organs, including the respiratory system. NPY and the Y1 receptor have critical roles in the pathogenesis of asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis. The effects of NPY on the airway immune response and pathogenesis differ among respiratory diseases. This review focuses on the involvement of NPY in the airway immune response and pathogenesis of various respiratory diseases.
Keywords	neuropeptide y Y1 receptor airway immune response bronchial epithelial cells respiratory disease
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2024-04
Volume	volume78
Issue	issue2
Publisher	Okayama University Medical School
Start Page	95
End Page	106
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2024 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	38688827

Neuropeptide Y Antagonizes Development of Pulmonary Fibrosis through IL-1β Inhibition

FullText URL	fulltext20221223-3.pdf NA_Itano_Fig.pdf supl20221223-3.pdf NA_Itano_Supl.pdf
Author	Itano, Junko\| Taniguchi, Akihiko\| Senoo, Satoru\| Asada, Noboru\| Gion, Yuka\| Egusa, Yuria\| Guo, Lili\| Oda, Naohiro\| Araki, Kota\| Sato, Yasuharu\| Toyooka, Shinichi\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Miyahara, Nobuaki\|
Keywords	idiopathic pulmonary fibrosis NPY IL-1 beta; bleomycin bronchial epithelial cells
Note	Originally Published in:Itano J, Taniguchi A, Senoo S, Asada N, Gion Y, Egusa Y, Guo L, Oda N, Araki K, Sato Y, Toyooka S, Kiura K, Maeda Y, Miyahara N. Neuropeptide Y Antagonizes Development of Pulmonary Fibrosis through IL-1β Inhibition. Am J Respir Cell Mol Biol. 2022 Dec;67(6):654-665. DOI: 10.1165/rcmb.2021-0542OC Copyright © 2022 by the American Thoracic Society The final publication is available at https://doi.org/10.1165/rcmb.2021-0542OC \| This full-text will be available in Dec. 2023.\|
Published Date	2022-12
Publication Title	American Journal of Respiratory Cell and Molecular Biology
Volume	volume67
Issue	issue6
Publisher	American Thoracic Society
Start Page	654
End Page	665
ISSN	1044-1549
NCID	AA10707251
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 by the American Thoracic Society
File Version	author
PubMed ID	36122332
DOI	10.1165/rcmb.2021-0542oc
Web of Science KeyUT	000891796900010
Related Url	isVersionOf https://doi.org/10.1165/rcmb.2021-0542oc

Switching to Dupilumab from Other Biologics without a Treatment Interval in Patients with Severe Asthma: A Multi-Center Retrospective Study

FullText URL	fulltext.pdf
Author	Higo, Hisao\| Ichikawa, Hirohisa\| Arakawa, Yukako\| Mori, Yoshihiro\| Itano, Junko\| Taniguchi, Akihiko\| Senoo, Satoru\| Kimura, Goro\| Tanimoto, Yasushi\| Miyake, Kohei\| Katsuta, Tomoya\| Kataoka, Mikio\| Maeda, Yoshinobu\| Kiura, Katsuyuki\| Miyahara, Nobuaki\| Okayama Respiratory Disease Study Group (ORDSG)\|
Keywords	dupilumab severe asthma treatment interval eosinophilic chronic rhinosinusitis
Published Date	2023-08-09
Publication Title	Journal of Clinical Medicine
Volume	volume12
Issue	issue16
Publisher	MDPI
Start Page	5174
ISSN	2077-0383
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 by the authors.
File Version	publisher
PubMed ID	37629217
DOI	10.3390/jcm12165174
Web of Science KeyUT	001056259200001
Related Url	isVersionOf https://doi.org/10.3390/jcm12165174

Mycobacterium shinjukuense infection successfully treated with clarithromycin, rifampicin, and ethambutol

FullText URL	fulltext.pdf
Author	Nakamura, Kayo\| Murakami, Etsuko\| Kishino, Daizo\| Mashimo, Shuko\| Kurioka, Yusuke\| Shibata, Yusaku\| Taniguchi, Arihiko\| Higo, Hisao\| Hiramatsu, Yasushi\| Maeda, Yoshinobu\| Miyahara, Nobuaki\|
Keywords	Mycobacterium shinjukuense Nontuberculous mycobacterium Mycobacterium tuberculosis Clarithromycin
Published Date	2023-07-08
Publication Title	Respiratory Medicine Case Reports
Volume	volume45
Publisher	Elsevier
Start Page	101894
ISSN	2213-0071
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 by the authors.
File Version	publisher
PubMed ID	37485238
DOI	10.1016/j.rmcr.2023.101894
Web of Science KeyUT	001040257700001
Related Url	isVersionOf https://doi.org/10.1016/j.rmcr.2023.101894

Pulmonary Aspergilloma and Allergic Bronchopulmonary Aspergillosis Following the 2018 Heavy Rain Event in Western Japan

FullText URL	fulltext.pdf
Author	Ando, Eri\| Nakasuka, Takamasa\| Kubo, Toshio\| Taniguchi, Akihiko\| Ninomiya, Kiichiro\| Kato, Yuka\| Ichihara, Eiki\| Ohashi, Kadoaki\| Rai, Kammei\| Hotta, Katsuyuki\| Yamane, Masaomi\| Miyahara, Nobuaki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	pulmonary aspergilloma allergic bronchopulmonary aspergillosis disaster
Published Date	2022-02-01
Publication Title	Internal Medicine
Volume	volume61
Issue	issue3
Publisher	JAPAN SOC INTERNAL MEDICINE
Start Page	379
End Page	383
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	34373373
DOI	10.2169/internalmedicine.7124-21
Web of Science KeyUT	000752787300015
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.7124-21

Identification of targetable kinases in idiopathic pulmonary fibrosis

FullText URL	fulltext.pdf
Author	Higo, Hisao\| Ohashi, Kadoaki\| Tomida, Shuta\| Okawa, Sachi\| Yamamoto, Hiromasa\| Sugimoto, Seiichiro\| Senoo, Satoru\| Makimoto, Go\| Ninomiya, Kiichiro\| Nakasuka, Takamasa\| Nishii, Kazuya\| Taniguchi, Akihiko\| Kubo, Toshio\| Ichihara, Eiki\| Hotta, Katsuyuki\| Miyahara, Nobuaki\| Maeda, Yoshinobu\| Toyooka, Shinichi\| Kiura, Katsuyuki\|
Keywords	Idiopathic pulmonary fibrosis RNA sequencing Molecular therapeutic target Personalized therapy
Published Date	2022-02-07
Publication Title	Respiratory Research
Volume	volume23
Issue	issue1
Publisher	BMC
Start Page	20
ISSN	1465-993X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2022.
File Version	publisher
PubMed ID	35130915
DOI	10.1186/s12931-022-01940-y
Web of Science KeyUT	000752386100002
Related Url	isVersionOf https://doi.org/10.1186/s12931-022-01940-y

Reactive Oxygen Species and Antioxidative Defense in Chronic Obstructive Pulmonary Disease

FullText URL	fulltext.pdf
Author	Taniguchi, Akihiko\| Tsuge, Mitsuru\| Miyahara, Nobuaki\| Tsukahara, Hirokazu\|
Keywords	reactive oxygen species nitric oxide oxidant antioxidant oxidative stress chronic obstructive pulmonary disease cigarette smoke asymmetric dimethylarginine arginine biomarker
Published Date	2021-09-28
Publication Title	Antioxidants
Volume	volume10
Issue	issue10
Publisher	MDPI
Start Page	1537
ISSN	2076-3921
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	34679673
DOI	10.3390/antiox10101537
Web of Science KeyUT	000712653600001
Related Url	isVersionOf https://doi.org/10.3390/antiox10101537

The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury

FullText URL	fulltext.pdf
Author	Aokage, Toshiyuki\| Seya, Mizuki\| Hirayama, Takahiro\| Nojima, Tsuyoshi\| Iketani, Masumi\| Ishikawa, Michiko\| Terasaki, Yasuhiro\| Taniguchi, Akihiko\| Miyahara, Nobuaki\| Nakao, Atsunori\| Ohsawa, Ikuroh\| Naito, Hiromichi\|
Keywords	Acute respiratory distress syndrome Bleomycin-induced lung injury Macrophage Molecular hydrogen Lung fibrosis
Published Date	2021-10-31
Publication Title	BMC Pulmonary Medicine
Volume	volume21
Issue	issue1
Publisher	BMC
Start Page	339
ISSN	1471-2466
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021.
File Version	publisher
PubMed ID	34719405
DOI	10.1186/s12890-021-01712-2
Web of Science KeyUT	000713091800001
Related Url	isVersionOf https://doi.org/10.1186/s12890-021-01712-2

Marginal Zone Lymphoma and Lung Adenocarcinoma with an EGFR Exon 19 E746-S752del Mutation in a Patient with IgG4-related Disease

FullText URL	fulltext.pdf
Author	Okawa, Sachi\| Rai, Kammei\| Fujii, Nobuharu\| Gion, Yuka\| Ninomiya, Kiichiro\| Kato, Yuka\| Taniguchi, Akihiko\| Kubo, Toshio\| Ichihara, Eiki\| Ohashi, Kadoaki\| Miyahara, Nobuaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	EGFR IgG4-related disease marginal zone lymphoma osimertinib
Published Date	2021-09-01
Publication Title	Internal Medicine
Volume	volume60
Issue	issue17
Publisher	The Japanese Society of Internal Medicine
Start Page	2831
End Page	2837
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	33775999
DOI	10.2169/internalmedicine.6470-20
Web of Science KeyUT	000695856000020
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.6470-20

Managing Lung Cancer with Comorbid Interstitial Pneumonia

FullText URL	fulltext.pdf
Author	Ichihara, Eiki\| Miyahara, Nobuaki\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	lung cancer interstitial pneumonia
Published Date	2020-01-15
Publication Title	Internal Medicine
Volume	volume59
Issue	issue2
Publisher	日本内科学会
Start Page	163
End Page	167
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
Copyright Holders	© 2020 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	31534086
NAID	130007785095
DOI	10.2169/internalmedicine.3481-19
Web of Science KeyUT	000507577600002
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.3481-19

Nintedanib can be used safely and effectively for idiopathic pulmonary fibrosis with predicted forced vital capacity <= 50%: A multi-center retrospective analysis

FullText URL	fulltext.pdf
Author	Senoo, Satoru\| Miyahara, Nobuaki\| Taniguchi, Akihiko\| Oda, Naohiro\| Itano, Junko\| Higo, Hisao\| Hara, Naofumi\| Watanabe, Hiromi\| Kano, Hirohisa\| Suwaki, Toshimitsu\| Fuchimoto, Yasuko\| Kajimoto, Kazuhiro\| Ichikawa, Hirohisa\| Kudo, Kenichiro\| Shibayama, Takuo\| Tanimoto, Yasushi\| Kuyama, Shoichi\| Kanehiro, Arihiko\| Maeda, Yoshinobu\| Kiura, Katsuyuki\| Okayama Respiratory Disease Study Group (ORDSG)\|
Published Date	2020-08-27
Publication Title	PLoS ONE
Volume	volume15
Issue	issue8
Publisher	Public Library of Science
Start Page	e0236935
ISSN	1932-6203
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 Senoo et al.
File Version	publisher
PubMed ID	32853277
DOI	10.1371/journal.pone.0236935
Web of Science KeyUT	000566948800009
Related Url	isVersionOf https://doi.org/10.1371/journal.pone.0236935

Deterioration of high-resolution computed tomography findings predicts disease progression after initial decline in forced vital capacity in idiopathic pulmonary fibrosis patients treated with pirfenidone

FullText URL	fulltext.pdf figure.pptx
Author	Higo, Hisao\| Miyahara, Nobuaki\| Taniguchi, Akihiko\| Senoo, Satoru\| Itano, Junko\| Watanabe, Hiromi\| Oda, Naohiro\| Kayatani, Hiroe\| Ichikawa, Hirohisa\| Shibayama, Takuo\| Kajimoto, Kazuhiro\| Tanimoto, Yasushi\| Kanehiro, Arihiko\| Maeda, Yoshinobu\| Kiura, Katsuyuki\| OKAYAMA respiratory disease study group (ORDSG)\|
Keywords	Idiopathic pulmonary fibrosis High-resolution computed tomography Pirfenidone Forced vital capacity
Note	This fulltext is available in Feb. 2021.\|
Published Date	2020-02-23
Publication Title	Respiratory Investigation
Volume	volume58
Issue	issue3
Publisher	Elsevier
Start Page	185
End Page	189
ISSN	22125345
NCID	AA12579673
Content Type	Journal Article
language	English
File Version	author
PubMed ID	32102769
DOI	10.1016/j.resinv.2019.12.007
Web of Science KeyUT	000531841500009
Related Url	isVersionOf https://doi.org/10.1016/j.resinv.2019.12.007

Successful Re-administration of Osimertinib in Osimertinib-induced Interstitial Lung Disease with an Organizing Pneumonia Pattern: A Case Report and Literature Review

FullText URL	fulltext.pdf figs.pdf tables.pdf
Author	Itano, Junko\| Higo, Hisao\| Ohashi, Kadoaki\| Makimoto, Go\| Nishii, Kazuya\| Hotta, Katsuyuki\| Miyahara, Nobuaki\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	osimertinib drug-induced ILD reversed halo sign organizing pneumonia pattern re-administration
Published Date	2020-03-15
Publication Title	Internal Medicine
Volume	volume59
Issue	issue6
Publisher	The Japanese Society of Internal Medicine
Start Page	823
End Page	828
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by The Japanese Society of Internal Medicine
File Version	author
PubMed ID	31787696
DOI	10.2169/internalmedicine.3689-19
Web of Science KeyUT	000521137500011
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.3689-19

Long-term spontaneous remission with active surveillance in IgG4-related pleuritis: A case report and literature review

FullText URL	fulltext.pdf
Author	Makimoto, Go\| Ohashi, Kadoaki\| Taniguchi, Kohei\| Soh, Junichi\| Taniguchi, Akihiko\| Miyahara, Nobuaki\| Toyooka, Shinichi\| Yoshino, Tadashi\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	IgG4-related disease Pleural effusion Adenosine deaminase Pleural biopsy Spontaneous remission
Published Date	2019
Publication Title	Respiratory Medicine Case Reports
Volume	volume28
Publisher	Elsevier
Start Page	100938
ISSN	2213-0071
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 The Authors.
File Version	publisher
PubMed ID	31667074
DOI	10.1016/j.rmcr.2019.100938
Web of Science KeyUT	000511444900052
Related Url	isVersionOf https://doi.org/10.1016/j.rmcr.2019.100938

A case of axillary lymphadenitis caused by Mycobacterium intracellulare in an immunocompetent patient

FullText URL	fulltext.pdf
Author	Itano, Junko\| Ohashi, Kadoaki\| Senoo, Satoru\| Oda, Naohiro\| Nishii, Kazuya\| Taniguchi, Akihiko\| Miyahara, Nobuaki\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	Axillary lymphadenitis Mycobacterium avium complex infection Mycobacterium intracellulare
Published Date	2019
Publication Title	Respiratory Medicine Case Reports
Volume	volume28
Publisher	Elsevier
Start Page	100947
ISSN	2213-0071
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 The Authors.
File Version	publisher
PubMed ID	31681532
DOI	10.1016/j.rmcr.2019.100947
Web of Science KeyUT	000511444900001
Related Url	isVersionOf https://doi.org/10.1016/j.rmcr.2019.100947

IL-17A is essential to the development of elastase-induced pulmonary inflammation and emphysema in mice

Author	Kurimoto, Etsuko\| Miyahara, Nobuaki\| Kanehiro, Arihiko\| Waseda, Koichi\| Taniguchi, Akihiko\| Ikeda, Genyo\| Koga, Hikari\| Nishimori, Hisakazu\| Tanimoto, Yasushi\| Kataoka, Mikio\| Iwakura, Yoichiro\| Gelfand, Erwin W.\| Tanimoto, Mitsune\|
Published Date	2013-01-20
Publication Title	Respiratory Research
Volume	volume14
Content Type	Journal Article

Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway responses

Author	Koga, Hikari\| Miyahara, Nobuaki\| Fuchimoto, Yasuko\| Ikeda, Genyo\| Waseda, Koichi\| Ono, Katsuichiro\| Tanimoto, Yasushi\| Kataoka, Mikio\| Gelfand, Erwin W.\| Tanimoto, Mitsune\| Kanehiro, Arihiko\|
Published Date	2013-01-24
Publication Title	Respiratory Research
Volume	volume14
Content Type	Journal Article

新型インフルエンザウイルス（A/H1N1）感染後にARDSを来たした1例

Author	Taniguchi, Akihiko\| Miyahara, Nobuaki\| Nakahara, Atsushi\| Takata, Saburo\| Sakugawa, Ryo\| Nagano, Osamu\| Tanimoto, Yasushi\| Kanehiro, Arihiko\| Kiura, Katsuyuki\| Ujike, Yoshito\| Tanimoto, Mitsune\|
Published Date	2011-12-01
Publication Title	岡山医学会雑誌
Volume	volume123
Issue	issue3
Content Type	Journal Article

気管支喘息における抗原特異的 T cell clone の樹立とサイトカイン産生能に関する研究

Author	Miyahara, Nobuaki\|
Published Date	1994-08
Publication Title	岡山医学会雑誌
Volume	volume106
Issue	issue7-8
Content Type	Journal Article

気管支喘息における抗原特異的 T cell clone の樹立とサイトカイン産生能に関する研究

Author	宮原信明\|
Published Date	1994-12-31
Publication Title
Content Type	Thesis or Dissertation