| JaLCDOI | 10.18926/AMO/67663 |
|---|---|
| FullText URL | 78_5_387.pdf |
| Author | Naoe, Shota| Tanaka, Ayumi| Kanzaki, Norie| Takenaka, Reiju| Sakoda, Akihiro| Miyaji, Takaaki| Yamaoka, Kiyonori| Kataoka, Takahiro| |
| Abstract | Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required. Although several studies have used proteomics to investigate the effects of radon inhalation on body proteins, none has focused on brain proteins. In this study, we evaluated the expression status of proteins in murine brains using proteomic and multivariate analyses to identify those whose expressions changed following two days of radon inhalation at a concentration of 1,500 Bq/m3. We found associations of radon inhalation with the expressions of seven proteins related to neurotransmission and heat shock. These proteins may be proposed as biomarkers indicative of radon inhalation. Although further studies are required to obtain the detailed biological significance of these protein alterations, this study contributes to the elucidation of the biological effects of radon inhalation as a low-dose radiation. |
| Keywords | radon inhalation proteomics multivariate analysis brain oxidative stress |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 387 |
| End Page | 399 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/65749 |
|---|---|
| FullText URL | 77_4_387.pdf |
| Author | Kataoka, Takahiro| Habu, Hiroshi| Tanaka, Ayumi| Naoe, Shota| Murakami, Kaito| Fujimoto, Yuki| Yukimine, Ryohei| Takao, Soshi| Mitsunobu, Fumihiro| Yorifuji, Takashi| Yamaoka, Kiyonori| |
| Abstract | No epidemiological studies have examined the health effects of daily bathing in radon hot springs. In this cross-sectional study, we investigated the associations between radon hot spring bathing and health conditions. The target population was 5,250 adults ≥ 20 years old in the town of Misasa, Japan. We collected information about the participants’ bathing habits and alleviation of a variety of disease symptoms, and their self-rated health (SRH). Unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (CI) were calculated. In both the adjusted and unadjusted models of hypertension, significant associations between the > 1×/week hot spring bathing and the alleviation of hypertension symptoms were observed compared to the group whose hot spring bathing was <1×/week: adjusted model, OR 5.40 (95%CI: 1.98-14.74); unadjusted model, 3.67 (1.50-8.99) and for gastroenteritis: adjusted model, 9.18 (1.15-72.96); unadjusted model, 7.62 (1.59-36.49). Compared to the no-bathing group, higher SRH was significantly associated with both bathing < 1×/week: unadjusted model, 2.27 (1.53-3.37) and > 1×/week: adjusted model, 1.91 (1.15-3.19). These findings suggest that bathing in radon hot springs is associated with higher SRH and the alleviation of hypertension and gastroenteritis. |
| Keywords | radon hot spring bathing habit self-rated health cross-section study |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-08 |
| Volume | volume77 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 387 |
| End Page | 394 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37635139 |
| Web of Science KeyUT | 001163659800003 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Naoe, Shota| Fujimoto, Yuki| Murakami, Kaito| Yukimine, Ryohei| Tanaka, Ayumi| Yamaoka, Kiyonori| Kataoka, Takahiro| |
| Keywords | low-dose/high-dose-rate irradiation forced swim test alcohol oxidative stress antioxidants |
| Published Date | 2023-05-17 |
| Publication Title | Journal of Radiation Research |
| Volume | volume64 |
| Issue | issue4 |
| Publisher | Oxford University Press |
| Start Page | 635 |
| End Page | 643 |
| ISSN | 0449-3060 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 37205845 |
| DOI | 10.1093/jrr/rrad030 |
| Web of Science KeyUT | 000990840900001 |
| Related Url | isVersionOf https://doi.org/10.1093/jrr/rrad030 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kataoka, Takahiro| Naoe, Shota| Murakami, Kaito| Fujimoto, Yuki| Yukimine, Ryohei| Tanaka, Ayumi| Yamaoka, Kiyonori| |
| Keywords | autoimmune diseases cytokine antioxidant function lipopolysaccharide radon inhalation |
| Published Date | 2022-08-26 |
| Publication Title | International Journal Of Environmental Research And Public Health |
| Volume | volume19 |
| Issue | issue17 |
| Publisher | MDPI |
| Start Page | 10632 |
| ISSN | 1660-4601 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 36078348 |
| DOI | 10.3390/ijerph191710632 |
| Web of Science KeyUT | 000851073300001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijerph191710632 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kataoka, Takahiro| Ishida, Tsuyoshi| Naoe, Shota| Kanzaki, Norie| Sakoda, Akihiro| Tanaka, Hiroshi| Mitsunobu, Fumihiro| Yamaoka, Kiyonori| |
| Keywords | alcohol-induced liver damage oxidative stress antioxidative function ascorbic acid (AA) thoron |
| Published Date | 2022-07-11 |
| Publication Title | Journal Of Radiation Research |
| Publisher | Oxford University Press on behalf of The Japanese Radiation Research Society and Japanese Society for Radiation Oncology. |
| ISSN | 0449-3060 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022. |
| File Version | publisher |
| PubMed ID | 35818298 |
| DOI | 10.1093/jrr/rrac046 |
| Web of Science KeyUT | 000822986000001 |
| Related Url | isVersionOf https://doi.org/10.1093/jrr/rrac046 |
| FullText URL | fulltext20220414-2.pdf |
|---|---|
| Author | Yamaoka, Kiyonori| Kataoka, Takahiro| |
| Published Date | 2022 |
| Publication Title | Journal of Clinical Biochemistry and Nutrition |
| Volume | volume70 |
| Issue | issue2 |
| Publisher | The Society for Free Radical Research Japan |
| Start Page | 87 |
| End Page | 92 |
| ISSN | 0912-0009 |
| NCID | AA10710201 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 JCBN |
| File Version | publisher |
| PubMed ID | 35400814 |
| DOI | 10.3164/jcbn.21-85 |
| Web of Science KeyUT | 000763105900001 |
| Related Url | isVersionOf https://doi.org/10.3164/jcbn.21-85 |
| FullText URL | fulltext20220414-1.pdf |
|---|---|
| Author | Kataoka, Takahiro| Naoe, Shota| Murakami, Kaito| Yukimine, Ryohei| Fujimoto, Yuki| Kanzaki, Norie| Sakoda, Akihiro| Mitsunobu, Fumihiro| Yamaoka, Kiyonori| |
| Keywords | radon cytokine oxidative stress rheumatoid arthritis immunomodulation function |
| Published Date | 2022 |
| Publication Title | Journal of Clinical Biochemistry and Nutrition |
| Volume | volume70 |
| Issue | issue2 |
| Publisher | The Society for Free Radical Research Japan |
| Start Page | 154 |
| End Page | 159 |
| ISSN | 0912-0009 |
| NCID | AA10710201 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 JCBN |
| File Version | publisher |
| PubMed ID | 35400822 |
| DOI | 10.3164/jcbn.21-91 |
| Web of Science KeyUT | 000763105900009 |
| Related Url | isVersionOf https://doi.org/10.3164/jcbn.21-91 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kataoka, Takahiro| Shuto, Hina| Naoe, Shota| Yano, Junki| Kanzaki, Norie| Sakoda, Akihiro| Tanaka, Hiroshi| Hanamoto, Katsumi| Mitsunobu, Fumihiro| Terato, Hiroaki| Yamaoka, Kiyonori| |
| Keywords | radon oxidative DNA damage Mn-superoxide dismutase (SOD) 8-oxoguanine DNA glycosylase |
| Published Date | 2021-08-09 |
| Publication Title | Journal of Radiation Research |
| Volume | volume62 |
| Issue | issue5 |
| Publisher | Oxford University Press |
| Start Page | 861 |
| End Page | 867 |
| ISSN | 0449-3060 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021. |
| File Version | publisher |
| PubMed ID | 34370027 |
| DOI | 10.1093/jrr/rrab069 |
| Web of Science KeyUT | 000700078300014 |
| Related Url | isVersionOf https://doi.org/10.1093/jrr/rrab069 |
| FullText URL | fulltext.pdf Erratum.pdf |
|---|---|
| Author | Kataoka, Takahiro| Kanzaki, Norie| Sakoda, Akihiro| Shuto, Hina| Yano, Junki| Naoe, Shota| Tanaka, Hiroshi| Hanamoto, Katsumi| Terato, Hiroaki| Mitsunobu, Fumihiro| Yamaoka, Kiyonori| |
| Keywords | radon redox state oxidative stress antioxidative function principal component analysis |
| Published Date | 2021-01-27 |
| Publication Title | Journal of Radiation Research |
| Volume | volume62 |
| Issue | issue3 |
| Publisher | Oxford Univ Press |
| Start Page | 390 |
| End Page | 400 |
| ISSN | 0449-3060 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021. |
| File Version | publisher |
| PubMed ID | 33503655 |
| NAID | 120007042386 |
| DOI | 10.1093/jrr/rraa129 |
| Web of Science KeyUT | 000648970300003 |
| Related Url | isVersionOf https://doi.org/10.1093/jrr/rraa129 |
| JaLCDOI | 10.18926/AMO/61896 |
|---|---|
| FullText URL | 75_2_169.pdf |
| Author | Nakada, Tetsuya| Kataoka, Takahiro| Nomura, Takaharu| Shuto, Hina| Yano, Junki| Naoe, Shota| Hanamoto, Katsumi| Yamaoka, Kiyonori| |
| Abstract | The forced swim test (FST) induces immobility in mice. Low-dose (high-dose-rate) X-irradiation inhibits FSTinduced immobility in mice due to its antioxidative function. We evaluated the effects of low-dose γ-irradiation at a low-dose-rate on the FST-induced depletion of antioxidants in mouse organs. Mice received whole-body low-dose-rate (0.6 or 3.0 mGy/h) of low-dose γ-irradiation for 1 week, followed by daily FSTs (5 days). The immobility rate on day 2 compared to day 1 was significantly lower in the 3.0 mGy/h irradiated mice than in sham irradiated mice. The FST significantly decreased the catalase (CAT) activity and total glutathione (t-GSH) content in the brain and kidney, respectively. The superoxide dismutase (SOD) activity and t-GSH content in the liver of the 3.0 mGy/h irradiated mice were significantly lower than those of the non-FST-treated mice. The CAT activity in the lungs of mice exposed to 3.0 mGy/h γ-irradiation was higher than that of non-FST treated mice and mice treated with FST. However, no significant differences were observed in the levels of these antioxidant markers between the sham and irradiated groups except for the CAT activity in lungs. These findings suggest that the effects of low-dose-rate and low-dose γ-irradiation on FST are highly organ-dependent. |
| Keywords | low-dose-rate γ-irradiation forced swim test antioxidant oxidative stress |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 169 |
| End Page | 175 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953424 |
| NAID | 120007029890 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kataoka, Takahiro| Shuto, Hina| Yano, Junki| Naoe, Shota| Ishida, Tsuyoshi| Nakada, Tetsuya| Yamato, Keiko| Hanamoto, Katsumi| Nomura, Takaharu| Yamaoka, Kiyonori| |
| Keywords | X-irradiation forced swim test antioxidants brain oxidative stress |
| Published Date | 2020-04-29 |
| Publication Title | Journal of Radiation Research |
| Volume | volume61 |
| Issue | issue4 |
| Publisher | OXFORD UNIV PRESS |
| Start Page | 517 |
| End Page | 523 |
| ISSN | 0449-3060 |
| NCID | AA00705792 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Crown copyright 2020. |
| File Version | publisher |
| PubMed ID | 32346734 |
| DOI | 10.1093/jrr/rraa022 |
| Web of Science KeyUT | 000593101500002 |
| Related Url | isVersionOf https://doi.org/10.1093/jrr/rraa022 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kobashi, Yusuke| Kataoka, Takahiro| Kanzaki, Norie| Ishida, Tsuyoshi| Sakoda, Akihiro| Tanaka, Hiroshi| Ishimori, Yuu| Mitsunobu, Fumihiro| Yamaoka, Kiyonori| |
| Keywords | Radon Thoron Oxidative stress Antioxidative function |
| Note | This is an Accepted Manuscript of an article published by Springer.| |
| Published Date | 2020-04-22 |
| Publication Title | Radiation and Environmental Biophysics |
| Volume | volume59 |
| Issue | issue3 |
| Publisher | Springer |
| ISSN | 0301634X |
| NCID | AA00800192 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 32322961 |
| DOI | 10.1007/s00411-020-00843-0 |
| Web of Science KeyUT | 000528077400001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00411-020-00843-0 |
| Author | Toyota, Teruaki| Kataoka, Takahiro| Nishiyama, Yuichi| Taguchi, Takehito| Yamaoka, Kiyonori| |
|---|---|
| Published Date | 2012 |
| Publication Title | Mediators of Inflammation |
| Volume | volume2012 |
| Content Type | Journal Article |
| Author | Kataoka, Takahiro| Nishiyama, Yuichi| Yamato, Keiko| Teraoka, Junichi| Morii, Yuji| Sakoda, Akihiro| Ishimori, Yuu| Taguchi, Takehito| Yamaoka, Kiyonori| |
|---|---|
| Published Date | 2012-07-31 |
| Publication Title | Journal of Radiation Research |
| Volume | volume53 |
| Issue | issue6 |
| Content Type | Journal Article |
| Author | Kataoka, Takahiro| Yamato, Keiko| Nishiyama, Yuichi| Morii, Yuji| Etani, Reo| Takata, Yuji| Hanamoto, Katsumi| Kawabe, Atsuishi| Sakoda, Akihiro| Ishimori, Yuu| Taguchi, Takehito| Yamaoka, Kiyonori| |
|---|---|
| Published Date | 2012-10 |
| Publication Title | Renal Failure |
| Volume | volume34 |
| Issue | issue9 |
| Content Type | Journal Article |
| Author | Kataoka, Takahiro| Tokunaga, Rikizo| Sakoda, Akihiro| Kawabe, Atsushi| Hanamoto, Katsumi| Yamaoka, Kiyonori| |
|---|---|
| Published Date | 2012-01-27 |
| Publication Title | RADIOISOTOPES |
| Volume | volume61 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Nakagawa, Shinya| Kataoka, Takahiro| Sakoda, Akihiro| Ishimori, Yuu| Hanamoto, Katsumi| Yamaoka, Kiyonori| |
|---|---|
| Published Date | 2008-04-25 |
| Publication Title | RADIOISOTOPES |
| Volume | volume57 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Nishiyama, Yuichi| Kataoka, Takahiro| Teraoka, Junichi| Sakoda, Akihiro| Ishimori, Yuu| Yamaoka, Kiyonori| |
|---|---|
| Published Date | 2012-05-29 |
| Publication Title | RADIOISOTOPES |
| Volume | volume61 |
| Issue | issue5 |
| Content Type | Journal Article |
| Author | Kataoka, Takahiro| Sakoda, Akihiro| Yoshimoto, Masaaki| Nakagawa, Shinya| Toyota, Teruaki| Nishiyama, Yuichi| Yamato, Keiko| Ishimori, Yuu| Kawabe, Atsushi| Hanamoto, Katsumi| Taguchi, Takehito| Yamaoka, Kiyonori| |
|---|---|
| Published Date | 2011-07 |
| Publication Title | Radiation Protection Dosimetry |
| Volume | volume146 |
| Issue | issue1-3 |
| Content Type | Journal Article |
| Author | Kataoka, Takahiro| Yoshimoto, Masaaki| Nakagawa, Shinya| Mizuguchi, Yuko| Taguchi, Takehito| Yamaoka, Kiyonori| |
|---|---|
| Published Date | 2009-09 |
| Publication Title | Journal of Clinical Biochemistry and Nutrition |
| Volume | volume45 |
| Issue | issue2 |
| Content Type | Journal Article |
