Author Hagiya, Hideharu| Fujita, Yasushi| Kiguchi, Takashi| Manabe, Yohei|
Keywords COVID-19 Immunization Reimbursement Healthcare workers Financial support
Note © 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Feb. 2026.|
Published Date 2025-03
Publication Title Journal of Infection and Chemotherapy
Volume volume31
Issue issue3
Publisher Elsevier BV
Start Page 102660
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 39956368
DOI 10.1016/j.jiac.2025.102660
Web of Science KeyUT 001428904200001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2025.102660
FullText URL fulltext.pdf
Author Izumi, Mahiro| Hagiya, Hideharu| Otsuka, Yuki| Soejima, Yoshiaki| Fukushima, Shinnosuke| Shibata, Mitsunobu| Hirota, Satoshi| Koyama, Toshihiro| Otsuka, Fumio| Gofuku, Akio|
Keywords Infection prevention and control Medical-engineering collaboration
Published Date 2025-01
Publication Title American Journal of Infection Control
Volume volume53
Issue issue1
Publisher Elsevier BV
Start Page 65
End Page 69
ISSN 0196-6553
NCID AA10617749
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Author(s).
File Version publisher
PubMed ID 39127185
DOI 10.1016/j.ajic.2024.08.003
Web of Science KeyUT 001402079000001
Related Url isVersionOf https://doi.org/10.1016/j.ajic.2024.08.003
Author Fukushima, Shinnosuke| Sumida, Takaomi| Kawamata, Osamu| Hidani, Yoshimi| Hagiya, Hideharu|
Keywords Global warming Japanese spotted fever Tick bite Tick-borne diseases
Note © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jan. 2026.|
Published Date 2024-12-02
Publication Title Journal of Infection and Chemotherapy
Volume volume31
Issue issue2
Publisher Elsevier
Start Page 102570
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 39631676
DOI 10.1016/j.jiac.2024.11.020
Web of Science KeyUT 001400947800001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2024.11.020
Author Fukushima, Shinnosuke| Hagiya, Hideharu| Gotoh, Kazuyoshi| Tsuji, Shuma| Iio, Koji| Akazawa, Hidemasa| Matsushita, Osamu| Otsuka, Fumio|
Keywords Antimicrobial resistance Corynebacterium Daptomycin High-level daptomycin resistance pgsA2
Note © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jan. 2026.|
Published Date 2024-12-03
Publication Title Journal of Infection and Chemotherapy
Volume volume31
Issue issue2
Publisher Elsevier
Start Page 102575
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 39638285
DOI 10.1016/j.jiac.2024.12.004
Web of Science KeyUT 001416617600001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2024.12.004
Author Shimbe, Madoka| Otsuka, Yuki| Hagiya, Hideharu| Yamada, Yoichi| Otsuka, Fumio|
Keywords Cervical cancer Human Papillomavirus Immunization Vaccine literacy
Note © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jan. 2026.|
Published Date 2024-11-05
Publication Title Journal of Infection and Chemotherapy
Volume volume31
Issue issue2
Publisher Elsevier
Start Page 102554
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 39510445
DOI 10.1016/j.jiac.2024.11.004
Web of Science KeyUT 001416618400001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2024.11.004
Author Oguni, Kohei| Fukushima, Shinnosuke| Hagiya, Hideharu| Kato, Atsushi| Suyama, Atsuhito| Iwata, Takehiro| Miyawaki, Yoshia| Ono, Sawako| Iio, Koji| Otsuka, Fumio|
Keywords Cryptococcosis Fluconazole Glucocorticoids Prostatitis Tocilizumab
Note © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jan. 2026.|
Published Date 2025-01
Publication Title Journal of Infection and Chemotherapy
Volume volume31
Issue issue1
Publisher Elsevier
Start Page 102494
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 39152054
DOI 10.1016/j.jiac.2024.08.009
Web of Science KeyUT 001419817400001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2024.08.009
FullText URL fulltext.pdf
Author Fukushima, Shinnosuke| Saito, Takashi| Iwamoto, Yoshitaka| Takehara, Yuko| Yamada, Haruto| Fujita, Koji| Yoshida, Masayo| Nakano, Yasuhiro| Hagiya, Hideharu|
Keywords Epidemiology Group A Streptococcus Necrotizing fasciitis Streptococcal toxic shock syndrome Surveillance
Note The version of record of this article, first published in European Journal of Clinical Microbiology & Infectious Diseases, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10096-024-05015-2|
Published Date 2024-12-16
Publication Title European Journal of Clinical Microbiology & Infectious Diseases
Publisher Springer Science and Business Media LLC
ISSN 0934-9723
NCID AA10686413
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39680263
DOI 10.1007/s10096-024-05015-2
Web of Science KeyUT 001378370400001
Related Url isVersionOf https://doi.org/10.1007/s10096-024-05015-2
JaLCDOI 10.18926/AMO/67873
FullText URL 78_6_465.pdf
Author Ocho, Kazuki| Hagiya, Hideharu| Ishikawa, Hisashi| Otsuka, Fumio|
Abstract An 81-year-old Japanese man with a medical history of diabetes mellitus and hypertension was diagnosed with the novel coronavirus disease 2019 (COVID-19). The patient developed pain in the bilateral shoulders and hips 3 days after the disease onset and presented to our outpatient clinic after 1 month. Referring to diagnostic criteria, we diagnosed him with polymyalgia rheumatica (PMR). We initiated prednisolone at 15 mg per day and his symptoms improved immediately. The clinical course of the patient indicated that the SARS-CoV-2 infection triggered the onset of autoimmune disease, PMR in this case.
Keywords COVID-19 SARS-CoV-2 polymyalgia rheumatica autoimmune diseases human leukocyte antigen
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-12
Volume volume78
Issue issue6
Publisher Okayama University Medical School
Start Page 465
End Page 468
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
FullText URL fulltext.pdf
Author Munetomo, Sosuke| Uchiyama, Jumpei| Takemura-Uchiyama, Iyo| Wanganuttara, Thamonwan| Yamamoto, Yumiko| Tsukui, Toshihiro| Hagiya, Hideharu| Kanamaru, Shuji| Kanda, Hideyuki| Matsushita, Osamu|
Published Date 2024-10-23
Publication Title PLoS ONE
Volume volume19
Issue issue10
Publisher Public Library of Science
Start Page e0310962
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Munetomo et al.
File Version publisher
PubMed ID 39441843
DOI 10.1371/journal.pone.0310962
Web of Science KeyUT 001345720700068
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0310962
Author Hagiya, Hideharu|
Keywords Sepsis Continuous infusion Prolonged infusion Pharmacokinetics
Note © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Oct. 2025.|
Published Date 2024-12
Publication Title Journal of Infection and Chemotherapy
Volume volume30
Issue issue12
Publisher Elsevier BV
Start Page 1324
End Page 1326
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 38977073
DOI 10.1016/j.jiac.2024.07.003
Web of Science KeyUT 001332640700001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2024.07.003
JaLCDOI 10.18926/AMO/67657
FullText URL 78_5_371.pdf
Author Gotoh, Kazuyoshi| Miyoshi, Makoto| I Putu Bayu Mayura| Tsuji, Shuma| Iio, Koji| Fukushima, Shinnosuke| Matsushita, Osamu| Hagiya, Hideharu|
Abstract Spread of carbapenemase-producing Enterobacterales (CPE) is an ongoing public health issue worldwide, including in Japan. In this study, we investigated the phenotypic and genetic characteristics of CPE isolates at Okayama University Hospital over the 5 years (2013-2018) prior to the outbreak of the 2019 coronavirus pandemic. Of 24 carbapenem-resistant Enterobacterales isolated during the study period, we identified 8 CPE isolates harboring blaIMP-1 (5 isolates) and blaIMP-6 genes (3 isolates). Bacterial species and carbapenem susceptibility patterns exhibited diversity. Minimum inhibitory concentrations (MICs) of meropenem were generally higher than those of imipenem and biapenem. Results of pulsed-field gel electrophoresis demonstrated that neither clonal nor plasmid-mediated outbreaks of blaIMP-harboring CPE isolates have developed at our hospital. One Klebsiella oxytoca isolate showed a high MIC (128 μg/mL) of meropenem, which could be explained by the high plasmid copy number. Subsequent analysis of this isolate may elucidate the intricacies of carbapenem resistance profiles among CPE isolates. Collectively, our findings underscore the necessity for ongoing genetic surveillance of CPE, complemented by tailored approaches for infection prevention and control.
Keywords antimicrobial resistance carbapenemase-producing enterobacterales carbapenemase-resistant enterobacterales Silent pandemic whole genome sequence
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-10
Volume volume78
Issue issue5
Publisher Okayama University Medical School
Start Page 371
End Page 376
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
FullText URL fulltext.pdf
Author Tsuge, Mitsuru| Ichihara, Eiki| Hasegawa, Kou| Kudo, Kenichiro| Tanimoto, Yasushi| Nouso, Kazuhiro| Oda, Naohiro| Mitsumune, Sho| Kimura, Goro| Yamada, Haruto| Takata, Ichiro| Mitsuhashi, Toshiharu| Taniguchi, Akihiko| Tsukahara, Kohei| Aokage, Toshiyuki| Hagiya, Hideharu| Toyooka, Shinichi| Tsukahara, Hirokazu| Maeda, Yoshinobu|
Keywords novel coronavirus disease 2019 pneumonia hydroperoxide nitric oxide reactive oxygen species citrulline arginine asymmetric dimethylarginine
Published Date 2024-07-31
Publication Title International Journal of Molecular Sciences
Volume volume25
Issue issue15
Publisher MDPI
Start Page 8370
ISSN 1661-6596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 39125944
DOI 10.3390/ijms25158370
Web of Science KeyUT 001286890700001
Related Url isVersionOf https://doi.org/10.3390/ijms25158370
FullText URL fulltext.pdf
Author Nahar, Lutfun| Hagiya, Hideharu| Gotoh, Kazuyoshi| Asaduzzaman, Md| Otsuka, Fumio|
Keywords antimicrobial resistance carbapenemase-producing Enterobacterales carbapenem-resistant Enterobacterales metallo-beta-lactamase synergy combination
Published Date 2024-07-18
Publication Title Journal of Clinical Medicine
Volume volume13
Issue issue14
Publisher MDPI
Start Page 4199
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 39064239
DOI 10.3390/jcm13144199
Web of Science KeyUT 001278470400001
Related Url isVersionOf https://doi.org/10.3390/jcm13144199
Author Tsuji, Shuma| Gotoh, Kazuyoshi| Manabe, Tadahiro| Iio, Koji| Fukushima, Shinnosuke| Matsushita, Osamu| Hagiya, Hideharu|
Keywords Beta-lactamase blaZ Cefazolin Inoculum effect Staphylococcus aureus
Note © 2024 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jun. 2025.|
Published Date 2024-09
Publication Title Diagnostic Microbiology and Infectious Disease
Volume volume110
Issue issue1
Publisher Elsevier BV
Start Page 116399
ISSN 0732-8893
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Elsevier Inc.
File Version author
PubMed ID 38875894
DOI 10.1016/j.diagmicrobio.2024.116399
Web of Science KeyUT 001255589200001
Related Url isVersionOf https://doi.org/10.1016/j.diagmicrobio.2024.116399
JaLCDOI 10.18926/AMO/67195
FullText URL 78_3_205.pdf
Author Hagiya, Hideharu|
Abstract The global pandemic of COVID-19 has underscored the significance of establishing and sustaining a practical and efficient infection control system for the benefit and welfare of society. Infectious disease (ID) specialists are expected to take on leadership roles in enhancing organizational infrastructures for infection prevention and control (IPC) at the hospital, community, and national levels. However, due to an absolute shortage and an uneven distribution, many core hospitals currently lack the ID specialists. Given the escalating global risk of emerging and re-emerging infectious diseases as well as antimicrobial resistance pathogens, the education and training of ID specialists constitutes an imperative concern. As demonstrated by historical changes in the healthcare reimbursement system, the establishment and enhancement of IPC measures is pivotal to ensuring medical safety. The existing structure of academic society-driven certification and training initiatives for ID specialists, contingent upon the discretionary decisions of individual physicians, possesses both quantitative and qualitative shortcomings. In this article, I first address the present situations and challenges related to ID specialists and then introduce my idea of securing ID specialists based on the new concepts and platforms; (i) ID Specialists as National Credentials, (ii) Establishment of the Department of Infectious Diseases in Medical and Graduate Schools, (iii) Endowed ID Educative Courses Funded by Local Government and Pharmaceutical Companies, and (iv) Recruitment of Young Physicians Engaged in Healthcare Services in Remote Areas. As clarified by the COVID-19 pandemic, ID specialists play a crucial role in safeguarding public health. Hopefully, this article will advance the discussion and organizational reform for the education and training of ID specialists.
Keywords antimicrobial resistance emerging infectious diseases infection prevention and control medical education silent pandemic
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2024-06
Volume volume78
Issue issue3
Publisher Okayama University Medical School
Start Page 205
End Page 213
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38902208
Web of Science KeyUT 001267351000001
FullText URL fulltext.pdf
Author Shibata, Masashi| Otsuka, Yuki| Hagiya, Hideharu| Koyama, Toshihiro| Kashiwagi, Hideyuki| Otsuka, Fumio|
Published Date 2024-02-28
Publication Title PLoS ONE
Volume volume19
Issue issue2
Publisher Public Library of Science
Start Page e0299700
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Shibata et al.
File Version publisher
PubMed ID 38416759
DOI 10.1371/journal.pone.0299700
Web of Science KeyUT 001181689500043
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0299700
FullText URL fulltext.pdf
Author Nakano, Yasuhiro| Sunada, Naruhiko| Tokumasu, Kazuki| Honda, Hiroyuki| Otsuka, Yuki| Sakurada, Yasue| Matsuda, Yui| Hasegawa, Toru| Omura, Daisuke| Ochi, Kanako| Yasuda, Miho| Hagiya, Hideharu| Ueda, Keigo| Otsuka, Fumio|
Keywords Diabetes mellitus Endocrine disorders Long COVID Metabolic disorders Thyroid disease
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-55526-3|
Published Date 2024-03-05
Publication Title Scientific Reports
Volume volume14
Issue issue1
Publisher Nature Portfolio
Start Page 5446
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38443459
DOI 10.1038/s41598-024-55526-3
Web of Science KeyUT 001180457200009
Related Url isVersionOf https://doi.org/10.1038/s41598-024-55526-3
FullText URL fulltext.pdf
Author Fukushima, Shinnosuke| Hagiya, Hideharu| Honda, Hiroyuki| Ishida, Tomoharu| Shoji, Ryohei| Hasegawa, Kou| Otsuka, Fumio|
Keywords Bacteremia Calcium polystyrene sulfonate Escherichia coli Infective endocarditis Rectal ulcer
Note The version of record of this article, first published in Clinical Journal of Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12328-024-01949-4|
Published Date 2024-03-25
Publication Title Clinical Journal of Gastroenterology
Volume volume17
Issue issue3
Publisher Springer Science and Business Media LLC
Start Page 472
End Page 476
ISSN 1865-7257
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38528197
DOI 10.1007/s12328-024-01949-4
Web of Science KeyUT 001190477300001
Related Url isVersionOf https://doi.org/10.1007/s12328-024-01949-4
FullText URL fulltext.pdf
Author Oka, Kosuke| Tokumasu, Kazuki| Hagiya, Hideharu| Otsuka, Fumio|
Keywords C-reactive protein (CRP) fever of unknown origin (FUO) functional hyperthermia (FH) psychiatric disorder psychogenic fever
Published Date 2024-02-03
Publication Title Journal of Clinical Medicine
Volume volume13
Issue issue3
Publisher MDPI
Start Page 889
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38337583
DOI 10.3390/jcm13030889
Web of Science KeyUT 001159108700001
Related Url isVersionOf https://doi.org/10.3390/jcm13030889
FullText URL fulltext.pdf
Author Yamamoto, Koichiro| Honda, Hiroyuki| Hasegawa, Kou| Hagiya, Hideharu| Otsuka, Fumio|
Keywords cavernosal abscess sepsis urinary catheter
Published Date 2024-02-19
Publication Title Clinical Case Reports
Volume volume12
Issue issue2
Publisher Wiley
Start Page e8534
ISSN 2050-0904
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Authors.
File Version publisher
PubMed ID 38380380
DOI 10.1002/ccr3.8534
Web of Science KeyUT 001164976300001
Related Url isVersionOf https://doi.org/10.1002/ccr3.8534