FullText URL | fulltext.pdf |
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Author | Kojima, Toru| Umeda, Yuzo| Fuji, Tomokazu| Niguma, Takefumi| Satoh, Daisuke| Endo, Yoshikatsu| Sui, Kenta| Inagaki, Masaru| Oishi, Masahiro| Ota, Tetsuya| Hioki, Katsuyoshi| Matsuda, Tadakazu| Aoki, Hideki| Hirai, Ryuji| Kimura, Masashi| Yagi, Takahito| Fujiwara, Toshiyoshi| |
Published Date | 2020-09-03 |
Publication Title | PLOS ONE |
Volume | volume15 |
Issue | issue9 |
Publisher | PUBLIC LIBRARY SCIENCE |
Start Page | e0238392 |
ISSN | 1932-6203 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 Kojima et al. |
File Version | publisher |
PubMed ID | 32881910 |
DOI | 10.1371/journal.pone.0238392 |
Web of Science KeyUT | 000571063300054 |
Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0238392 |
FullText URL | fulltext.pdf |
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Author | Takagi, Kosei| Kuise, Takashi| Umeda, Yuzo| Yoshida, Ryuichi| Teraishi, Fuminori| Yagi, Takahito| Fujiwara, Toshiyoshi| |
Keywords | Laparoscopic Liver Segment seven |
Published Date | 2020 |
Publication Title | International Journal of Surgery Case Reports |
Volume | volume73 |
Publisher | Elsevier |
Start Page | 168 |
End Page | 171 |
ISSN | 2210-2612 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Author(s). |
File Version | publisher |
PubMed ID | 32688239 |
DOI | 10.1016/j.ijscr.2020.06.107 |
Web of Science KeyUT | 000558775100010 |
Related Url | isVersionOf https://doi.org/10.1016/j.ijscr.2020.06.107 |
Title Alternative | The 32th Annual Meeting of the Japan Society for Biological Therapy |
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FullText URL | 132_41.pdf |
Author | Fujiwara, Toshiyoshi| |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2020-04-01 |
Volume | volume132 |
Issue | issue1 |
Start Page | 41 |
End Page | 43 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.132.41 |
language | Japanese |
Copyright Holders | Copyright (c) 2020 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.132.41 |
NAID | 130007840310 |
FullText URL | fulltext.pdf |
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Author | Maeda, Naoaki| Shirakawa, Yasuhiro| Tanabe, Shunsuke| Sakurama, Kazufumi| Noma, Kazuhiro| Fujiwara, Toshiyoshi| |
Published Date | 2020-06-26 |
Publication Title | World Journal of Surgical Oncology |
Volume | volume18 |
Issue | issue1 |
Publisher | BMC |
Start Page | 143 |
ISSN | 1477-7819 |
NCID | AA12048269 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s). 2020 |
File Version | publisher |
PubMed ID | 32591002 |
DOI | 10.1186/s12957-020-01908-6 |
Web of Science KeyUT | 000545948700003 |
Related Url | isVersionOf https://doi.org/10.1186/s12957-020-01908-6 |
FullText URL | fulltext.pdf |
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Author | Koujima, Takeshi| Tazawa, Hiroshi| Ieda, Takeshi| Araki, Hiroyuki| Fushimi, Takuro| Shoji, Ryohei| Kuroda, Shinji| Kikuchi, Satoru| Yoshida, Ryuichi| Umeda, Yuzo| Teraishi, Fuminori| Urata, Yasuo| Mizuguchi, Hiroyuki| Fujiwara, Toshiyoshi| |
Published Date | 2020-06-26 |
Publication Title | Molecular Therapy - Oncolytics |
Volume | volume17 |
Publisher | Cell Press |
Start Page | 107 |
End Page | 117 |
ISSN | 2372-7705 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Author(s). |
File Version | publisher |
PubMed ID | 32322667 |
DOI | 10.1016/j.omto.2020.03.016 |
Web of Science KeyUT | 000544101600010 |
Related Url | isVersionOf https://doi.org/10.1016/j.omto.2020.03.016 |
FullText URL | fulltext.pdf |
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Author | Tazawa, Hiroshi| Hasei, Joe| Yano, Shuya| Kagawa, Shunsuke| Ozaki, Toshifumi| Fujiwara, Toshiyoshi| |
Keywords | oncolytic adenovirus hTERT autophagy GFP p53 |
Published Date | 2020-02-18 |
Publication Title | Cancers |
Volume | volume12 |
Issue | issue2 |
Publisher | MDPI |
ISSN | 2072-6694 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32085583 |
DOI | 10.3390/cancers12020478 |
Web of Science KeyUT | 000522477300224 |
Related Url | isVersionOf https://doi.org/10.3390/cancers12020478 |
FullText URL | fulltext.pdf |
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Author | Matsubara, Takehiro| Soh, Junichi| Morita, Mizuki| Uwabo, Takahiro| Tomida, Shuta| Fujiwara, Toshiyoshi| Kanazawa, Susumu| Toyooka, Shinichi| Hirasawa, Akira| |
Published Date | 2020-02-27 |
Publication Title | BioMed Research International |
Volume | volume2020 |
Publisher | Hindawi |
Start Page | 9349132 |
ISSN | 2314-6133 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 Takehiro Matsubara et al. |
File Version | publisher |
PubMed ID | 32185225 |
DOI | 10.1155/2020/9349132 |
Web of Science KeyUT | 000522222100002 |
Related Url | isVersionOf https://doi.org/10.1155/2020/9349132 |
FullText URL | fulltext.pdf |
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Author | Yoshioka, Takahiro| Shien, Kazuhiko| Takeda, Tatsuaki| Takahashi, Yuta| Kurihara, Eisuke| Ogoshi, Yusuke| Namba, Kei| Torigoe, Hidejiro| Sato, Hiroki| Tomida, Shuta| Yamamoto, Hiromasa| Soh, Junichi| Fujiwara, Toshiyoshi| Toyooka, Shinichi| |
Keywords | afatinib gastric cancer HER2 MET YES1 |
Published Date | 2019-06-04 |
Publication Title | Cancer Science |
Volume | volume110 |
Issue | issue8 |
Publisher | Wiley Open Access |
Start Page | 2549 |
End Page | 2557 |
ISSN | 1347-9032 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2019 The Authors. |
File Version | publisher |
PubMed ID | 31162771 |
DOI | 10.1111/cas.14089 |
Web of Science KeyUT | 000478616800022 |
Related Url | isVersionOf https://doi.org/10.1111/cas.14089 |
FullText URL | fulltext.pdf Graphical_Abstract.pptx Figure1-6.pdf Supp_Info.pdf |
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Author | Kanaya, Nobuhiko| Kuroda, Shinji| Kakiuchi, Yoshihiko| Kumon, Kento| Tsumura, Tomoko| Hashimoto, Masashi| Morihiro, Toshiaki| Kubota, Tetsushi| Aoyama, Katsuyuki| Kikuchi, Satoru| Nishizaki, Masahiko| Kagawa, Shunsuke| Tazawa, Hiroshi| Mizuguchi, Hiroyuki| Urata, Yasuo| Fujiwara, Toshiyoshi| |
Keywords | immune checkpoint programmed death-1 oncolytic adenovirus combined immunotherapy immunogenic cell death tumor infiltrating lymphocytes CD8 abscopal effect |
Published Date | 2020-01-10 |
Publication Title | Molecular Therapy |
Volume | volume28 |
Issue | issue3 |
Publisher | Cell Press |
Start Page | 794 |
End Page | 804 |
ISSN | 15250016 |
NCID | AA11475060 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 31991110 |
DOI | 10.1016/j.ymthe.2020.01.003 |
Web of Science KeyUT | 000518887200012 |
Related Url | isVersionOf https://doi.org/10.1016/j.ymthe.2020.01.003 |
Author | Ieda, Takeshi| Tazawa, Hiroshi| Okabayashi, Hiroki| Yano, Shuya| Shigeyasu, Kunitoshi| Kuroda, Shinji| Ohara, Toshiaki| Noma, Kazuhiro| Kishimoto, Hiroyuki| Nishizaki, Masahiko| Kagawa, Shunsuke| Shirakawa, Yasuhiro| Saitou, Takashi| Imamura, Takeshi| Fujiwara, Toshiyoshi| |
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Published Date | 2019-11-8 |
Publication Title | Scientific Reports |
Volume | volume9 |
Publisher | Nature Publishing Group |
Start Page | 16378 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2019 |
File Version | publisher |
PubMed ID | 31705021 |
DOI | 10.1038/s41598-019-52816-z |
Web of Science KeyUT | 000495372900001 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-019-52816-z |
FullText URL | SR9_1_4633.pdf |
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Author | Morihiro, Toshiaki| Kuroda, Shinji| Kanaya, Nobuhiko| Kakiuchi, Yoshihiko| Kubota, Tetsushi| Aoyama, Katsuyuki| Tanaka, Takehiro| Kikuch, Satoru| Nagasaka, Takeshi| Nishizaki, Masahiko| Kagawa, Shunsuke| Tazawa, Hiroshi| Fujiwara, Toshiyoshi| |
Published Date | 2019-3-15 |
Publication Title | Scientific Reports |
Volume | volume9 |
Publisher | Nature Publishing Group |
Start Page | 4633 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2019 |
File Version | publisher |
PubMed ID | 30874607 |
DOI | 10.1038/s41598-019-41177-2 |
Web of Science KeyUT | 000461303000015 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-019-41177-2 |
FullText URL | AGS3_1_96.pdf SI.pdf |
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Author | Kuroda, Shinji| Choda, Yasuhiro| Otsuka, Shinya| Ueyama, Satoshi| Tanaka, Norimitsu| Muraoka, Atsushi| Hato, Shinji| Kimura, Toshikazu| Tanakaya, Kohji| Kikuchi, Satoru| Tanabe, Shunsuke| Noma, Kazuhiro| Nishizaki, Masahiko| Kagawa, Shunsuke| Shirakawa, Yasuhiro| Kamikawa, Yasuaki| Fujiwara, Toshiyoshi| |
Keywords | Kamikawa procedure antireflux surgery double‐flap technique esophagogastrostomy proximal gastrectomy |
Published Date | 2018-10-11 |
Publication Title | Annals of Gastroenterological Surgery |
Volume | volume3 |
Issue | issue1 |
Publisher | Woley |
Start Page | 96 |
End Page | 103 |
ISSN | 2475-0328 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2018 The Authors |
File Version | publisher |
PubMed ID | 30697614 |
DOI | 10.1002/ags3.12216 |
Web of Science KeyUT | 000456643500012 |
Related Url | isVersionOf https://doi.org/10.1002/ags3.12216 |
FullText URL | cancers_11_2_177.pdf |
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Author | Katsura, Yuki| Ohara, Toshiaki| Noma, Kazuhiro| Ninomiya, Takayuki| Kashima, Hajime| Kato, Takuya| Sato, Hiroaki| Komoto, Satoshi| Narusaka, Toru| Tomono, Yasuko| Xing, Boyi| Chen, Yuehua| Tazawa, Hiroshi| Kagawa, Shunsuke| Shirakawa, Yasuhiro| Kasai , Tomonari| Seno, Masaharu| Matsukawa, Akihiro| Fujiwara, Toshiyoshi| |
Keywords | cancer stem cells combination therapy iron stemness |
Published Date | 2019-02-03 |
Publication Title | Cancers |
Volume | volume11 |
Issue | issue2 |
Publisher | MDPI |
Start Page | 177 |
ISSN | 2072-6694 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2019 by the authors |
File Version | publisher |
PubMed ID | 30717462 |
DOI | 10.3390/cancers11020177 |
Web of Science KeyUT | 000460747200051 |
Related Url | isVersionOf https://doi.org/10.3390/cancers11020177 |
FullText URL | OncoImmunol_8_12_1671760.pdf |
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Author | Sakamoto, Shuichi| Kagawa, Shunsuke| Kuwada, Kazuya| Ito, Atene| Kajioka, Hiroki| Kakiuchi, Yoshihiko| Watanabe, Megumi| Kagawa, Tetsuya| Yoshida, Ryuichi| Kikuchi, Satoru| Kuroda, Shinji| Tazawa, Hiroshi| Fujiwara, Toshiyoshi| |
Keywords | Gastric cancer tumor-associated macrophages tumor microenvironment peritoneal dissemination |
Published Date | 2019-10-22 |
Publication Title | OncoImmunology |
Volume | volume8 |
Issue | issue12 |
Publisher | TAYLOR & FRANCIS |
Start Page | e1671760 |
ISSN | 2162402X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2019 The Author(s). |
File Version | publisher |
DOI | 10.1080/2162402X.2019.1671760 |
Web of Science KeyUT | 000494085400001 |
Related Url | isVersionOf https://doi.org/10.1080/2162402X.2019.1671760 |
FullText URL | AnnGastroenterolSurg_3_4_396.pdf |
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Author | Fujiwara, Toshiyoshi| |
Keywords | adenovirus clinical trial esophageal cancer radiotherapy telomerase |
Published Date | 2019-07-05 |
Publication Title | Annals of gastroenterological surgery |
Volume | volume3 |
Issue | issue4 |
Publisher | John Wiley & Sons |
Start Page | 396 |
End Page | 404 |
ISSN | 24750328 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2019 The Authors |
File Version | publisher |
PubMed ID | 31346579 |
DOI | 10.1002/ags3.12270 |
Web of Science KeyUT | 000475745100009 |
Related Url | isVersionOf https://doi.org/10.1002/ags3.12270 |
JaLCDOI | 10.18926/AMO/54981 |
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FullText URL | 71_2_127.pdf |
Author | Shirakawa, Yasuhiro| Noma, Kazuhiro| Maeda, Naoaki| Tanabe, Shunsuke| Kuroda, Shinji| Kagawa, Shunsuke| Katsui, Kuniaki| Katayama, Norihisa| Kanazawa, Susumu| Fujiwara, Toshiyoshi| |
Abstract | Currently, chemoradiation is the most widely used nonsurgical treatment for esophageal cancer. However, some patients, particularly the very elderly or those with severe vital organ dysfunction, face difficulty with the chemotherapy component. We therefore examined the outcome of radiation therapy (RT) alone for patients with esophageal cancer at our facility. Between January 2005 and December 2014, 84 patients underwent RT at our hospital, and 78 of these patients received concomitant chemotherapy. The remaining 6 patients underwent RT alone; these patients were considered to be high-risk and to have no lymph node metastasis (stage I). Five of them received irradiation up to a curative dose: 4 showed a complete response (CR) and 1 showed a partial response (PR). Of the patients exhibiting CR, 3 are currently living recurrence-free, whereas 1 patient underwent endoscopic submucosal dissection (ESD) as salvage therapy for local recurrence, with no subsequent recurrence. High-risk stage I esophageal cancer patients can be treated radically with RT alone under certain conditions. In the future, to broaden the indications for RT monotherapy to include some degree of advanced cancers, a novel concurrent therapy should be identified. |
Keywords | esophageal cancer radiation therapy high-risk patient |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2017-04 |
Volume | volume71 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 127 |
End Page | 133 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2017 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 28420894 |
Title Alternative | Thoracoscopic esophagectomy was effective in a case of lower esophageal stenosis due to recurrence of achalasia after myotomy 40 years previously |
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FullText URL | 129_41.pdf |
Author | Katsura, Yuki| Shirakawa, Yasuhiro| Tanabe, Shunsuke| Maeda, Naomi| Noma, Kazuhiro| Fujiwara, Toshiyoshi| |
Abstract | When planning surgery for achalasia, it is important to plan for adequate myotomy and prevention of reflux. However, achalasia may recur if the procedure was inadequate or in patients with a long-term course. The present case is a 68-year-old woman who underwent myotomy of the lower esophageal sphincter 40 years ago, but recently reported difficulty in swallowing. Dilatation of the thoracic esophagus and stenosis of the abdominal esophagus were identified by examination, and the patient was diagnosed with recurrence of achalasia. After percutaneous endoscopic gastrostomy was performed to recover nutritional status, thoracoscopic esophagectomy was carried out. The patient'spost-operative course was uneventful and oral intake was enabled. At the time of writing, there has been no re-recurrence. There is no standard therapy for post-operative recurrence of achalasia. We believe that thoracoscopic esophagectomy for the recurrence of achalasia is a safe and minimally invasive alternative to conventional surgery. |
Keywords | 食道アカラシア (achalasia) 再手術 (reoperation) 食道亜全摘 (esophagectomy) |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2017-04-03 |
Volume | volume129 |
Issue | issue1 |
Start Page | 41 |
End Page | 44 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2017 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.129.41 |
NAID | 130005632071 |
Author | Takagi, Kosei| Yagi, Takahito| Shinoura, Susumu| Umeda, Yuzo| Yoshida, Ryuichi| Nobuoka, Daisuke| Watanabe, Nobuyuki| Kuise, Takashi| Fuji, Tomokazu| Araki, Hiroyuki| Fujiwara, Toshiyoshi| |
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Published Date | 2017-02 |
Publication Title | Acta Medica Okayama |
Volume | volume71 |
Issue | issue1 |
Content Type | Journal Article |
JaLCDOI | 10.18926/AMO/54830 |
JaLCDOI | 10.18926/AMO/54601 |
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FullText URL | 70_5_401.pdf |
Author | Kuroda, Shinji| Kikuchi, Satoru| Nishizaki, Masahiko| Kagawa, Shunsuke| Hinotsu, Shiro| Fujiwara, Toshiyoshi| |
Abstract | Although intermittent pneumatic compression (IPC) has become common as perioperative prophylaxis for venous thromboembolism (VTE) consisting of pulmonary thromboembolism (PE) and deep vein thrombosis (DVT), the prophylactic effect against VTE, especially lethal PE, is not yet satisfactory. Therefore, pharmacologic prophylaxis, such as with enoxaparin, is desirable. While the efficacy and safety of enoxaparin have been proven in several clinical trials, concern about bleeding with longterm (at least 7 days) use have potentially decreased its widespread adoption. We have launched a phase II study to evaluate the efficacy and safety of short-term (3 days) enoxaparin, in which a total of 70 gastric cancer patients undergoing gastrectomy will be recruited, and the primary endpoint is the incidence of DVT. This study could contribute to making pharmacologic prophylaxis for VTE more common. |
Keywords | venous thromboembolism enoxaparin short-term use gastric cancer surgery |
Amo Type | Clinical Study Protocols |
Publication Title | Acta Medica Okayama |
Published Date | 2016-10 |
Volume | volume70 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 401 |
End Page | 404 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 27777435 |
Web of Science KeyUT | 000388098700012 |
JaLCDOI | 10.18926/AMO/54594 |
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FullText URL | 70_5_363.pdf |
Author | Takagi, Kosei| Yagi, Takahito| Yoshida, Ryuichi| Shinoura, Susumu| Umeda, Yuzo| Nobuoka, Daisuke| Kuise, Takashi| Watanabe, Nobuyuki| Fujiwara, Toshiyoshi| |
Abstract | Sarcopenia following liver surgery has been reported as a predictor of poor prognosis. Here we investigated predictors of outcomes in patients with hepatocellular carcinoma (HCC) and attempted to establish a new comprehensive preoperative assessment protocol. We retrospectively analyzed the cases of 254 patients who underwent curative hepatectomy for HCC with Child-Pugh classification A at our hospital between January 2007 and December 2013. Sarcopenia was evaluated by computed tomography measurement. The influence of sarcopenia on outcomes was evaluated. We used multivariate analyses to assess the impact of prognostic factors associated with outcomes, including sarcopenia. Of the 254 patients, 118 (46.5%) met the criteria for sarcopenia, and 32 had an American Society of Anesthesiologists (ASA) physical status ≥3. The sarcopenic group had a significantly lower 5-year overall survival rate than the non-sarcopenic group (58.2% vs. 82.4% , p=0.0002). In multivariate analyses of prognostic factors, sarcopenia was an independent predictor of poor survival (hazard ratio [HR]=2.28, p=0.002) and poor ASA status (HR=3.17, p=0.001). Sarcopenia and poor ASA status are independent preoperative predictors for poor outcomes after hepatectomy. The preoperative identification of sarcopenia and ASA status might enable the development of comprehensive approaches to assess surgical eligibility. |
Keywords | sarcopenia American Society of Anesthesiologists physical status hepatectomy hepatocellular carcinoma prognostic factor |
Amo Type | Original Articles |
Publication Title | Acta Medica Okayama |
Published Date | 2016-10 |
Volume | volume70 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 363 |
End Page | 370 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 27777428 |
Web of Science KeyUT | 000388098700005 |