Fujiwara, Toshiyoshi - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Perioperative Multidisciplinary Intervention Led to Complete Minimally Invasive Transthoracic Esophagectomy for a Patient With Severe Lung Dysfunction: A Case Report

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Author	Matsumoto, Makoto\| Hashimoto, Masashi\| Kawasaki, Kento\| Kunitomo, Tomoyoshi\| Maeda, Naoaki\| Tanabe, Shunsuke\| Noma, Kazuhiro\| Fujiwara, Toshiyoshi\|
Keywords	copd esophagectomy perioperative multidisciplinary intervention perioperative rehabilitation respiratory function training and rehabilitation sarcopenia severe pulmonary dysfunction
Published Date	2025-11-27
Publication Title	Cureus
Volume	volume17
Issue	issue11
Publisher	Springer Science and Business Media LLC
Start Page	e97931
ISSN	2168-8184
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Copyright 2025 Matsumoto et al.
File Version	publisher
PubMed ID	41458865
DOI	10.7759/cureus.97931
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A Procedural Transhiatal Approach for the Thoracic Para‐Aortic Lymph Node: A Case Report

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Author	Hashimoto, Masashi\| Noma, Kazuhiro\| Takeda, Yasushige\| Matsumoto, Hijiri\| Kawasaki, Kento\| Kunitomo, Tomoyoshi\| Maeda, Naoaki\| Tanabe, Shunsuke\| Fujiwara, Toshiyoshi\|
Keywords	112aoP esophageal cancer thoracic posterior para-aortic lymph node
Published Date	2025-01
Publication Title	Asian Journal of Endoscopic Surgery
Volume	volume18
Issue	issue1
Publisher	Wiley
Start Page	e70066
ISSN	1758-5902
NCID	AA12488501
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	40269550
DOI	10.1111/ases.70066
Web of Science KeyUT	001473127600001
Related Url	isVersionOf https://doi.org/10.1111/ases.70066

Gut microbial metabolite butyrate boosts p53-expressing telomerase-specific oncolytic adenovirus efficacy by enhancing infectivity and activating MHC-I/cGAS-STING

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Author	Sakamoto, Masaki\| Kuroda, Shinji\| Katayama, Tetsuya\| Mikane, Yu\| Hanzawa, Shunya\| Kadowaki, Daisuke\| Yoshida, Yusuke\| Hamada, Yuki\| Sugimoto, Ryoma\| Yagi, Chiaki\| Hashimoto, Masashi\| Kanaya, Nobuhiko\| Kakiuchi, Yoshihiko\| Kikuchi, Satoru\| Shigeyasu, Kunitoshi\| Tazawa, Hiroshi\| Kagawa, Shunsuke\| Urata, Yasuo\| Fujiwara, Toshiyoshi\|
Keywords	Butyrate Oncolytic adenovirus MHC-I CD8 + T cells Cancer immunotherapy
Published Date	2025-12-18
Publication Title	Cancer Immunology, Immunotherapy
Volume	volume75
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	10
ISSN	1432-0851
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	41410712
DOI	10.1007/s00262-025-04252-4
Web of Science KeyUT	001643413800004
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がん治療用ウイルス製剤の創薬研究―遺伝子治療からウイルス療法への展開―

Title Alternative	Clinical development of oncolytic virotherapy for cancer: From gene therapy to virotherapy
Author	Fujiwara, Toshiyoshi\|
Keywords	消化器がんテロメラーゼアデノウイルス食道癌 p53がん抑制遺伝子
Publication Title	Journal of Okayama Medical Association
Published Date	2025-12-01
Volume	volume137
Issue	issue3
Start Page	98
End Page	107
ISSN	0030-1558
Related Url	isVersionOf https://doi.org/10.4044/joma.137.98
language	Japanese
Copyright Holders	Copyright (c) 2025 岡山医学会
File Version	publisher
DOI	10.4044/joma.137.98

P53-Armed Oncolytic Virotherapy Promotes the Efficacy of PD1 Blockade in Murine Osteosarcoma Tumors

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Author	KURE, MIHO\| TAZAWA, HIROSHI\| DEMIYA, KOJI\| KONDO, HIROYA\| MOCHIZUKI, YUSUKE\| KOMATSUBARA, TADASHI\| YOSHIDA, AKI\| UOTANI, KOJI\| HASEI, JOE\| FUJIWARA, TOMOHIRO\| KUNISADA, TOSHIYUKI\| URATA, YASUO\| KAGAWA, SHUNSUKE\| OZAKI, TOSHIFUMI\| FUJIWARA, TOSHIYOSHI\|
Keywords	Osteosarcoma oncolytic adenovirus P53 immunogenic cell death PD1
Published Date	2025-12-30
Publication Title	Anticancer Research
Volume	volume46
Issue	issue1
Publisher	International Institute of Anticancer Research
Start Page	69
End Page	84
ISSN	0250-7005
NCID	AA10625860
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	©2026 The Author(s).
File Version	publisher
PubMed ID	41469103
DOI	10.21873/anticanres.17924
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Near-infrared Photoimmunotherapy Targeting High-risk Human Neuroblastoma Cells Expressing GD2

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Author	NOUSO, HIROSHI\| TAZAWA, HIROSHI\| TANIMOTO, TERUTAKA\| TANI, MORIMICHI\| WATANABE, HINAKO\| OYAMA, TAKANORI\| NOMA, KAZUHIRO\| KAGAWA, SHUNSUKE\| KOBAYASHI, HISATAKA\| NODA, TAKUO\| KURODA, SHINJI\| FUJIWARA, TOSHIYOSHI\|
Keywords	Neuroblastoma GD2 near-infrared photoimmunotherapy IR700
Published Date	2025-12-30
Publication Title	Anticancer Research
Volume	volume46
Issue	issue1
Publisher	International Institute of Anticancer Research
Start Page	25
End Page	38
ISSN	0250-7005
NCID	AA10625860
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	©2026 The Author(s).
File Version	publisher
PubMed ID	41469108
DOI	10.21873/anticanres.17921
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Enhancement of drug delivery through fibroblast activation protein–targeted near-infrared photoimmunotherapy

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Author	Nishimura, Seitaro\| Noma, Kazuhiro\| Matsumoto, Tasuku\| Takeda, Yasushige\| Takahashi, Tatsuya\| Matsumoto, Hijiri\| Kawasaki, Kento\| Kawai, Hotaka\| Kunitomo, Tomoyoshi\| Akai, Masaaki\| Kobayashi, Teruki\| Nishiwaki, Noriyuki\| Kashima, Hajime\| Kato, Takuya\| Kikuchi, Satoru\| Tanabe, Shunsuke\| Ohara, Toshiaki\| Tazawa, Hiroshi\| Shirakawa, Yasuhiro\| Choyke, Peter L.\| Kobayashi, Hisataka\| Fujiwara, Toshiyoshi\|
Published Date	2025-12-22
Publication Title	JCI Insight
Volume	volume10
Issue	issue24
Publisher	American Society for Clinical Investigation
Start Page	e195776
ISSN	2379-3708
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025, Nishimura et al.
File Version	publisher
PubMed ID	41424387
DOI	10.1172/jci.insight.195776
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Neoadjuvant FOLFOXIRI for locally advanced rectal cancer: A retrospective analysis focusing on long-term anal preservation

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Author	Shoji, Ryohei\| Teraishi, Fuminori\| Matsumi, Yuki\| Yoshida, Yusuke\| Kanaya, Nobuhiko\| Shigeyasu, Kunitoshi\| Kondo, Yoshitaka\| Mori, Yoshiko\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
Keywords	Locally advanced rectal cancer Neoadjuvant chemotherapy FOLFOXIRI Late pelvic toxicity
Published Date	2025
Publication Title	Cancer Treatment and Research Communications
Volume	volume45
Publisher	Elsevier BV
Start Page	101049
ISSN	2468-2942
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Authors.
File Version	publisher
PubMed ID	41338147
DOI	10.1016/j.ctarc.2025.101049
Web of Science KeyUT	001634811000001
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Tumor marker–guided precision BNCT for CA19-9–positive cancers: a new paradigm in molecularly targeted chemoradiation therapy

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Author	Kanehira, Noriyuki\| Teraishi, Fuminori\| Tajima, Tomoyuki\| Osone, Tatsunori\| Gotoh, Kazuyoshi\| Fujimoto, Takuya\| Sakurai, Yoshinori\| Kondo, Natsuko\| Nagahisa, Narikazu\| Kamei, Kaoru\| Fujita, Taiga\| Morihara, Akira\| Takaguchi, Yutaka\| Kitamatsu, Mizuki\| Takarada, Takeshi\| Shigeyasu, Kunitoshi\| Suzuki, Minoru\| Fujiwara, Toshiyoshi\| Michiue, Hiroyuki\|
Keywords	Boron neutron capture therapy (BNCT) Precision BNCT Fucose-conjugated medicine CA19-9 Drug discovery
Published Date	2025-12-08
Publication Title	Journal of Translational Medicine
Volume	volume23
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	1387
ISSN	1479-5876
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025.
File Version	publisher
PubMed ID	41361823
DOI	10.1186/s12967-025-07349-7
Web of Science KeyUT	001633595500002
Related Url	isVersionOf https://doi.org/10.1186/s12967-025-07349-7

Robotic posterior radical antegrade modular pancreatosplenectomy for left-sided pancreatic cancer using the ligament of Treitz first approach: A case report and technical note

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Author	Takagi, Kosei\| Fuji, Tomokazu\| Yasui, Kazuya\| Matsumoto, Kazuyuki\| Fujiwara, Toshiyoshi\|
Keywords	Radical antegrade modular pancreatosplenectomy Distal pancreatectomy Robotic surgery Ligament of Treitz Surgical approach
Published Date	2025-09
Publication Title	International Journal of Surgery Case Reports
Volume	volume134
Publisher	Elsevier BV
Start Page	111782
ISSN	2210-2612
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Authors.
File Version	publisher
PubMed ID	40773933
DOI	10.1016/j.ijscr.2025.111782
Web of Science KeyUT	001546812400006
Related Url	isVersionOf https://doi.org/10.1016/j.ijscr.2025.111782

p53-armed oncolytic adenovirus induces apoptosis in pancreatic cancer-associated stellate cells via macropinocytosis

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Author	Nishiyama, Takeyoshi\| Tazawa, Hiroshi\| Nagai, Yasuo\| Shoji, Ryohei\| Kajiwara, Yoshinori\| Hashimoto, Naoyuki\| Takahashi, Yosuke\| Kikuchi, Satoru\| Kuroda, Shinji\| Ohara, Toshiaki\| Noma, Kazuhiro\| Yoshida, Ryuichi\| Umeda, Yuzo\| Tanaka, Hiroyoshi Y.\| Kano, Mitsunobu R.\| Masamune, Atsushi\| Urata, Yasuo\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
Published Date	2025-11-28
Publication Title	Cancer Gene Therapy
Publisher	Springer Science and Business Media LLC
ISSN	0929-1903
NCID	AA11052453
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	41315733
DOI	10.1038/s41417-025-00989-3
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Gallbladder edema as a clue to zolbetuximab-associated protein-losing enteropathy in gastric cancer: a case report

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Author	Kakiuchi, Yoshihiko\| Kuroda, Shinji\| Hanzawa, Shunya\| Kanaya, Nobuhiko\| Kashima, Hajime\| Kikuchi, Satoru\| Shigeyasu, Kunitoshi\| Kono, Yoshiyasu\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
Keywords	Gastric cancer Zolbetuximab CLDN 18.2 Protein-losing enteropathy Gallbladder edema
Published Date	2025-09-30
Publication Title	Gastric Cancer
Volume	volume28
Issue	issue6
Publisher	Springer Science and Business Media LLC
Start Page	1297
End Page	1301
ISSN	1436-3291
NCID	AA11316227
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	41026396
DOI	10.1007/s10120-025-01668-w
Web of Science KeyUT	001584118400001
Related Url	isVersionOf https://doi.org/10.1007/s10120-025-01668-w

Neoadjuvant chemotherapy strategies for optimizing safety and efficacy in elderly patients with locally advanced gastric cancer

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Author	Kakiuchi, Yoshihiko\| Kuroda, Shinji\| Hanzawa, Shunya\| Kanaya, Nobuhiko\| Kashima, Hajime\| Kikuchi, Satoru\| Shigeyasu, Kunitoshi\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
Keywords	Gastric cancer Neoadjuvant chemotherapy Elderly Adverse events
Published Date	2025-09-29
Publication Title	BMC Gastroenterology
Volume	volume25
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	670
ISSN	1471-230X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025.
File Version	publisher
PubMed ID	41023595
DOI	10.1186/s12876-025-04281-4
Web of Science KeyUT	001586088500005
Related Url	isVersionOf https://doi.org/10.1186/s12876-025-04281-4

Serum extracellular vesicles containing adenoviral E1A-DNA as a predictive biomarker for liquid biopsy in oncolytic adenovirus therapy

FullText URL	fulltext.pdf
Author	Yagi, Chiaki\| Kuroda, Shinji\| Kakiuchi, Yoshihiko\| Hanzawa, Shunya\| Kadowaki, Daisuke\| Yoshida, Yusuke\| Sakamoto, Masaki\| Hamada, Yuki\| Sugimoto, Ryoma\| Ohtani, Tomoko\| Kumon, Kento\| Hashimoto, Masashi\| Kanaya, Nobuhiko\| Kikuchi, Satoru\| Kagawa, Shunsuke\| Tazawa, Hiroshi\| Urata, Yasuo\| Fujiwara, Toshiyoshi\|
Keywords	Oncolytic adenovirus Extracellular vesicle Liquid biopsy Predictive biomarker Stealth effect
Published Date	2025-11-04
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	38590
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	41188286
DOI	10.1038/s41598-025-22389-1
Web of Science KeyUT	001608929900046
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Gemcitabine-induced neutrophil extracellular traps via interleukin-8-CXCR1/2 pathway promote chemoresistance in pancreatic cancer

FullText URL	fulltext.pdf
Author	Nogi, Shohei\| Kagawa, Shunsuke\| Taniguchi, Atsuki\| Yagi, Tomohiko\| Kanaya, Nobuhiko\| Kakiuchi, Yoshihiko\| Yasui, Kazuya\| Fuji, Tomokazu\| Kono, Yoshiyasu\| Kikuchi, Satoru\| Takagi, Kosei\| Kuroda, Shinji\| Teraishi, Fuminori\| Tazawa, Hiroshi\| Fujiwara, Toshiyoshi\|
Published Date	2025-09-25
Publication Title	British Journal of Cancer
Publisher	Springer Science and Business Media LLC
ISSN	0007-0920
NCID	AA00574355
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40993312
DOI	10.1038/s41416-025-03192-1
Web of Science KeyUT	001577720100001
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Tertiary Lymphoid Structures Are Associated with Favorable Clinical Outcomes and Negatively Correlated with Cancer-Associated Fibroblasts in Esophageal Cancer

FullText URL	fulltext.pdf suppl.pdf
Author	Kunitomo, Tomoyoshi\| Noma, Kazuhiro\| Nishiwaki, Noriyuki\| Nishimura, Seitaro\| Takeda, Yasushige\| Matsumoto, Hijiri\| Takahashi, Tatsuya\| Kawasaki, Kento\| Akai, Masaaki\| Maeda, Naoaki\| Kikuchi, Satoru\| Tanabe, Shunsuke\| Ohara, Toshiaki\| Tazawa, Hiroshi\| Shirakawa, Yasuhiro\| Fujiwara, Toshiyoshi\|
Keywords	tertiary lymphoid structures (TLSs) cancer-associated fibroblasts (CAFs) esophageal cancer tumor microenvironment prognosis
Published Date	2025-10-17
Publication Title	Cancers
Volume	volume17
Issue	issue20
Publisher	MDPI AG
Start Page	3351
ISSN	2072-6694
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 by the authors.
File Version	publisher
PubMed ID	41154405
DOI	10.3390/cancers17203351
Web of Science KeyUT	001602403800001
Related Url	isVersionOf https://doi.org/10.3390/cancers17203351

Impact of Neoadjuvant Chemotherapy with Gemcitabine Plus S-1 in Patients with Resectable Pancreatic Ductal Adenocarcinoma

FullText URL	fulltext.pdf
Author	Yasui, Kazuya\| Takagi, Kosei\| Fuji, Tomokazu\| Nishiyama, Takeyoshi\| Nagai, Yasuo\| Matsumoto, Kazuyuki\| Horiguchi, Shigeru\| Fujii, Yuki\| Otsuka, Motoyuki\| Fujiwara, Toshiyoshi\|
Keywords	neoadjuvant chemotherapy pancreatic cancer resectable textbook outcome
Published Date	2025-10-10
Publication Title	Cancers
Volume	volume17
Issue	issue20
Publisher	MDPI AG
Start Page	3287
ISSN	2072-6694
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 by the authors.
File Version	publisher
DOI	10.3390/cancers17203287
Related Url	isVersionOf https://doi.org/10.3390/cancers17203287

Gastroduodenal Artery-Preserving Pancreatoduodenectomy after Esophagectomy with Gastric Conduit Reconstruction

JaLCDOI	10.18926/AMO/69441
FullText URL	79_5_393.pdf
Author	Masunaga, Akari\| Takagi, Kosei\| Nagai, Yasuo\| Yasui, Kazuya\| Fuji, Tomokazu\| Yamada, Motohiko\| Nishiyama, Takeyoshi\| Kanehira, Noriyuki\| Sota, Yumi\| Fujiwara, Toshiyoshi\|
Abstract	Pancreatoduodenectomy (PD) after esophagectomy with gastric conduit reconstruction is technically challenging. Preserving the blood supply of the gastric conduit is crucial in performing PD after esophagectomy. We report the case of a 66-year-old man who underwent gastroduodenal artery-preserving PD after esophagectomy with gastric conduit reconstruction for intraductal papillary mucinous neoplasm. The patient developed pseudoaneurysm rupture postoperatively, but was successfully treated with interventional radiology. Precise assessment is important in developing a surgical strategy depending on the patient’s specific anatomy and tumor characteristics. Moreover, special attention should be paid to avoid accidental injuries of the gastric conduit and gastric vessels during surgery.
Keywords	pancreatoduodenectomy esophagectomy gastric conduit fluorescence imaging
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2025-10
Volume	volume79
Issue	issue5
Publisher	Okayama University Medical School
Start Page	393
End Page	398
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2025 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	41126471
Web of Science KeyUT	001606011100002

A case of retrograde colonic intussusception by tubulovillous adenoma

FullText URL	fulltext.pdf
Author	Iki, Michiko\| Kanaya, Nobuhiko\| Shoji, Ryohei\| Kakiuchi, Yoshihiko\| Kondo, Yoshitaka\| Kuroda, Shinji\| Shigeyasu, Kunitoshi\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
Keywords	Retrograde colonic intussusception Colonic polyp Multiple system atrophy Shy–Drager syndrome
Note	The version of record of this article, first published in Clinical Journal of Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12328-025-02205-z\|
Published Date	2025-08-25
Publication Title	Clinical Journal of Gastroenterology
Publisher	Springer Science and Business Media LLC
ISSN	1865-7257
NCID	AA12646624
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40855140
DOI	10.1007/s12328-025-02205-z
Web of Science KeyUT	001555966700001
Related Url	isVersionOf https://doi.org/10.1007/s12328-025-02205-z

Precise stratification of prognosis in pancreatic ductal adenocarcinoma patients based on pre- and postoperative genomic information

FullText URL	fulltext.pdf suppl.docx
Author	Miyamoto, Kokichi\| Yoshida, Ryuichi\| Yasui, Kazuya\| Shigeyasu, Kunitoshi\| Yoshida, Kazuhiro\| Fuji, Tomokazu\| Takagi, Kosei\| Umeda, Yuzo\| Matsumoto, Kazuyuki\| Fujii, Yuki\| Takahashi, Toshiaki\| Moriwake, Kazuya\| Kayano, Masashi\| Nishiyama, Takeyoshi\| Nagai, Yasuo\| Yamamoto, Hideki\| Kato, Hironari\| Tazawa, Hiroshi\| Morita, Mizuki\| Otsuka, Motoyuki\| Fujiwara, Toshiyoshi\|
Keywords	Pancreatic ductal adenocarcinoma Risk stratification Prognosis Tumour marker KRAS
Published Date	2025-08-18
Publication Title	Cancer Cell International
Volume	volume25
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	305
ISSN	1475-2867
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025.
File Version	publisher
PubMed ID	40826465
DOI	10.1186/s12935-025-03894-9
Related Url	isVersionOf https://doi.org/10.1186/s12935-025-03894-9