| FullText URL | fulltext.pdf |
|---|---|
| Author | Sugihara, Yuusaku| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Morito, Yuki| Takahashi, Sakuma| Harada, Keita| Tanaka, Takehiro| Otsuka, Fumio| Okada, Hiroyuki| |
| Keywords | graft-vs.-host disease terminal ileum allo-hematopoietic stem cell transplantation villous atrophy endoscopy |
| Published Date | 2020-02-21 |
| Publication Title | Experimental and Therapeutic Medicine |
| Volume | volume19 |
| Issue | issue4 |
| Publisher | Spandidos Publications |
| Start Page | 3076 |
| End Page | 3080 |
| ISSN | 1792-0981 |
| NCID | AA12610820 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Sugiharaet al. |
| File Version | publisher |
| PubMed ID | 32256795 |
| DOI | 10.3892/etm.2020.8538 |
| Web of Science KeyUT | 000523637100082 |
| Related Url | isVersionOf https://doi.org/10.3892/etm.2020.8538 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hamada, Kenta| Kanzaki, Hiromitsu| Inoue, Masafumi| Ishiyama , Shuhei| Yamauchi, Kenji| Miyahara, Koji| Toyokawa, Tatsuya| Tsuzuki, Takao| Miyaike, Jiro| Matsubara, Minoru| Takahashi, Sakuma| Nishimura, Mamoru| Takenaka, Ryuta| Yunoki, Naoko| Hori, Shinichiro| Kobayashi, Sayo| Yamasaki, Yasushi| Kawahara, Yoshiro| Ishikawa, Hideki| Okada, Hiroyuki| |
| Keywords | anticoagulant agent bleeding endoscopic submucosal dissection gastric cancer heparin replacement warfarin |
| Published Date | 2020-11-01 |
| Publication Title | Internal Medicine |
| Volume | volume59 |
| Issue | issue21 |
| Publisher | The Japanese Society of Internal Medicine |
| Start Page | 2643 |
| End Page | 2651 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 32641658 |
| DOI | 10.2169/internalmedicine.4998-20 |
| Web of Science KeyUT | 000589268900003 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.4998-20 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kinugasa, Hideaki| Hiraoka, Sakiko| Nouso, Kazuhiro| Yamamoto, Shumpei| Hirai, Mami| Terasawa, Hiroyuki| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Yamasaki, Yasushi| Inokuchi, Toshihiro| Takahara, Masahiro| Harada, Keita| Tanaka, Takehiro| Okada, Hiroyuki| |
| Keywords | IBD-associated neoplasia IBD-associated cancer Liquid biopsy ctDNA |
| Published Date | 2020-12-03 |
| Publication Title | BMC Cancer |
| Volume | volume20 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 1188 |
| ISSN | 1471-2407 |
| NCID | AA12034763 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). 2020 |
| File Version | publisher |
| PubMed ID | 33272240 |
| DOI | 10.1186/s12885-020-07699-z |
| Web of Science KeyUT | 000597268700004 |
| Related Url | isVersionOf https://doi.org/10.1186/s12885-020-07699-z |
| JaLCDOI | 10.18926/AMO/60363 |
|---|---|
| FullText URL | 74_4_265.pdf |
| Author | Inokuchi, Toshihiro| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahar, Masahiro| Kawano, Seiji| Harada, Keita| Okada, Hiroyuki| Kato, Jun| |
| Abstract | Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy. |
| Keywords | Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance |
| Amo Type | Original Article |
| Published Date | 2020-08 |
| Publication Title | Acta Medica Okayama |
| Volume | volume74 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 265 |
| End Page | 274 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32843757 |
| Web of Science KeyUT | 000562508700001 |
| NAID | 120006880202 |
| FullText URL | SR9_1_11934.pdf |
|---|---|
| Author | Takahara, Masahiro| Takaki, Akinobu| Hiraoka, Sakiko| Adach, Takuya| Shimomura, Yasuyuki| Matsushita, Hiroshi| Nguyen Tien Thi Thuy| Koike, Kazuko| Ikeda, Airi| Takashima, Shiho| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Sugihara, Yusaku| Harada, Keita| Eikawa, Shingo| Morita, Hidetoshi| Udono, Heiichiro| Okada, Hiroyuki| |
| Published Date | 2019-8-15 |
| Publication Title | Scientific Reports |
| Volume | volume9 |
| Publisher | Nature Publishing Group |
| Start Page | 11934 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2019 |
| File Version | Publisher |
| PubMed ID | 31417110 |
| DOI | 10.1038/s41598-019-48331-w |
| Web of Science KeyUT | 000480680800048 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-019-48331-w |
