Yamasaki, Yasushi - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Factors Predicting a Favorable Disease Course Without Anti-TNF Therapy in Crohn’s Disease Patients

JaLCDOI	10.18926/AMO/60363
FullText URL	74_4_265.pdf
Author	Inokuchi, Toshihiro\| Hiraoka, Sakiko\| Yasutomi, Eriko\| Oka, Shohei\| Yamasaki, Yasushi\| Kinugasa, Hideaki\| Takahar, Masahiro\| Kawano, Seiji\| Harada, Keita\| Okada, Hiroyuki\| Kato, Jun\|
Abstract	Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy.
Keywords	Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2020-08
Volume	volume74
Issue	issue4
Publisher	Okayama University Medical School
Start Page	265
End Page	274
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2020 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	32843757
Web of Science KeyUT	000562508700001
NAID	120006880202

Liquid biopsy for patients with IBD-associated neoplasia

FullText URL	fulltext.pdf
Author	Kinugasa, Hideaki\| Hiraoka, Sakiko\| Nouso, Kazuhiro\| Yamamoto, Shumpei\| Hirai, Mami\| Terasawa, Hiroyuki\| Yasutomi, Eriko\| Oka, Shohei\| Ohmori, Masayasu\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Takahara, Masahiro\| Harada, Keita\| Tanaka, Takehiro\| Okada, Hiroyuki\|
Keywords	IBD-associated neoplasia IBD-associated cancer Liquid biopsy ctDNA
Published Date	2020-12-03
Publication Title	BMC Cancer
Volume	volume20
Issue	issue1
Publisher	BMC
Start Page	1188
ISSN	1471-2407
NCID	AA12034763
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s). 2020
File Version	publisher
PubMed ID	33272240
DOI	10.1186/s12885-020-07699-z
Web of Science KeyUT	000597268700004
Related Url	isVersionOf https://doi.org/10.1186/s12885-020-07699-z

Continued Aspirin Treatment May Be a Risk Factor of Delayed Bleeding after Gastric Endoscopic Submucosal Dissection under Heparin Replacement: A Retrospective Multicenter Study

FullText URL	fulltext.pdf
Author	Hamada, Kenta\| Kanzaki, Hiromitsu\| Inoue, Masafumi\| Ishiyama , Shuhei\| Yamauchi, Kenji\| Miyahara, Koji\| Toyokawa, Tatsuya\| Tsuzuki, Takao\| Miyaike, Jiro\| Matsubara, Minoru\| Takahashi, Sakuma\| Nishimura, Mamoru\| Takenaka, Ryuta\| Yunoki, Naoko\| Hori, Shinichiro\| Kobayashi, Sayo\| Yamasaki, Yasushi\| Kawahara, Yoshiro\| Ishikawa, Hideki\| Okada, Hiroyuki\|
Keywords	anticoagulant agent bleeding endoscopic submucosal dissection gastric cancer heparin replacement warfarin
Published Date	2020-11-01
Publication Title	Internal Medicine
Volume	volume59
Issue	issue21
Publisher	The Japanese Society of Internal Medicine
Start Page	2643
End Page	2651
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	32641658
DOI	10.2169/internalmedicine.4998-20
Web of Science KeyUT	000589268900003
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.4998-20

Observer agreement for the diagnosis of intestinal acute graft‑vs.‑host disease based on the presence of villous atrophy in the terminal ileum

FullText URL	fulltext.pdf
Author	Sugihara, Yuusaku\| Hiraoka, Sakiko\| Yasutomi, Eriko\| Oka, Shohei\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Kinugasa, Hideaki\| Takahara, Masahiro\| Morito, Yuki\| Takahashi, Sakuma\| Harada, Keita\| Tanaka, Takehiro\| Otsuka, Fumio\| Okada, Hiroyuki\|
Keywords	graft-vs.-host disease terminal ileum allo-hematopoietic stem cell transplantation villous atrophy endoscopy
Published Date	2020-02-21
Publication Title	Experimental and Therapeutic Medicine
Volume	volume19
Issue	issue4
Publisher	Spandidos Publications
Start Page	3076
End Page	3080
ISSN	1792-0981
NCID	AA12610820
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Sugiharaet al.
File Version	publisher
PubMed ID	32256795
DOI	10.3892/etm.2020.8538
Web of Science KeyUT	000523637100082
Related Url	isVersionOf https://doi.org/10.3892/etm.2020.8538

Leucine-rich alpha-2 glycoprotein as a marker of mucosal healing in inflammatory bowel disease

FullText URL	fulltext.pdf
Author	Yasutomi, Eriko\| Inokuchi, Toshihiro\| Hiraoka, Sakiko\| Takei, Kensuke\| Igawa, Shoko\| Yamamoto, Shumpei\| Ohmori, Masayasu\| Oka, Shohei\| Yamasaki, Yasushi\| Kinugasa, Hideaki\| Takahara, Masahiro\| Harada, Keita\| Furukawa, Masaki\| Itoshima, Kouichi\| Okada, Ken\| Otsuka, Fumio\| Tanaka, Takehiro\| Mitsuhashi, Toshiharu\| Kato, Jun\| Okada, Hiroyuki\|
Published Date	2021-05-27
Publication Title	Scientific Reports
Volume	volume11
Issue	issue1
Publisher	Nature Research
Start Page	11086
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021
File Version	publisher
PubMed ID	34045529
NAID	120007089817
DOI	10.1038/s41598-021-90441-x
Web of Science KeyUT	000658389400001
Related Url	isVersionOf https://doi.org/10.1038/s41598-021-90441-x

The Impact of KRAS Mutation in Patients With Sporadic Nonampullary Duodenal Epithelial Tumors

FullText URL	fulltext.pdf
Author	Kinugasa, Hideaki\| Kanzaki, Hiromitsu\| Tanaka, Takehiro\| Yamamoto, Shumpei\| Yamasaki, Yasushi\| Nouso, Kazuhiro\| Ichimura, Kouichi\| Nakagawa, Masahiro\| Mitsuhashi, Toshiharu\| Okada, Hiroyuki\|
Published Date	2021-11
Publication Title	Clinical and Translational Gastroenterology
Volume	volume12
Issue	issue11
Publisher	Lippincott Williams & Wilkins
Start Page	e00424
ISSN	2155-384X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Author(s).
File Version	publisher
PubMed ID	34797780
DOI	10.14309/ctg.0000000000000424
Web of Science KeyUT	000720492100001
Related Url	isVersionOf https://doi.org/10.14309/ctg.0000000000000424

Application of convolutional neural networks for evaluating the depth of invasion of early gastric cancer based on endoscopic images

FullText URL	fulltext20211210-1.pdf
Author	Hamada, Kenta\| Kawahara, Yoshiro\| Tanimoto, Takayoshi\| Ohto, Akimitsu\| Toda, Akira\| Aida, Toshiaki\| Yamasaki, Yasushi\| Gotoda, Tatsuhiro\| Ogawa, Taiji\| Abe, Makoto\| Okanoue, Shotaro\| Takei, Kensuke\| Kikuchi, Satoru\| Kuroda, Shinji\| Fujiwara, Toshiyoshi\| Okada, Hiroyuki\|
Keywords	Artificial intelligence convolutional neural network early gastric cancer endoscopic image invasion depth
Note	This is the peer reviewed version of the following article: [Hamada, K., Kawahara, Y., Tanimoto, T., Ohto, A., Toda, A., Aida, T., Yamasaki, Y., Gotoda, T., Ogawa, T., Abe, M., Okanoue, S., Takei, K., Kikuchi, S., Kuroda, S., Fujiwara, T., and Okada, H. (2021) Application of convolutional neural networks for evaluating the depth of invasion of early gastric cancer based on endoscopic images, Journal of Gastroenterology and Hepatology], which has been published in final form at [https://doi.org/10.1111/jgh.15725]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\|
Published Date	2021-11-25
Publication Title	Journal of Gastroenterology and Hepatology
Publisher	Wiley
Start Page	1
ISSN	0815-9319
NCID	AA10727383
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd
File Version	author
PubMed ID	34713495
DOI	10.1111/jgh.15725
Web of Science KeyUT	000722466600001
Related Url	isVersionOf https://doi.org/10.1111/jgh.15725

Clinicopathological Characteristics of Superficial Barrett's Adenocarcinoma in a Japanese Population: A Retrospective, Multicenter Study

FullText URL	fulltext.pdf
Author	Hamada, Kenta\| Kanzaki, Hiromitsu\| Miyahara, Koji\| Nakagawa, Masahiro\| Mouri, Hirokazu\| Mizuno, Motowo\| Takahashi, Sakuma\| Hori, Shinichiro\| Nasu, Junichiro\| Tsuzuki, Takao\| Miyaike, Jiro\| Takenaka, Ryuta\| Yamauchi, Kenji\| Kobayashi, Sayo\| Toyokawa, Tatsuya\| Inoue, Masafumi\| Nishimura, Mamoru\| Matsubara, Minoru\| Tomoda, Jun\| Yamasaki, Yasushi\| Tanaka, Takehiro\| Shirakawa, Yasuhiro\| Kawahara, Yoshiro\| Fujiwara, Toshiyoshi\| Okada, Hiroyuki\| Okayama Gut Study Group\|
Keywords	Barrett's adenocarcinoma endoscopic resection long -segment Barrett's esophagus metachronous lesion short -segment Barrett's esophagus surgery
Published Date	2022-04-15
Publication Title	INTERNAL MEDICINE
Volume	volume61
Issue	issue8
Publisher	The Japanese Society of Internal Medicine
Start Page	1115
End Page	1123
ISSN	0918-2918
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	35431302
DOI	10.2169/internalmedicine.6942-20
Web of Science KeyUT	000789463700001
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.6942-20

The Colon Wall Thickness Measured Using Transabdominal Ultrasonography Is Useful for Detecting Mucosal Inflammation in Ulcerative Colitis

FullText URL	fulltext.pdf
Author	Takahara, Masahiro\| Hiraoka, Sakiko\| Ohmori, Masayasu\| Takeuchi, Keiko\| Takei, Kensuke\| Yasutomi, Eriko\| Igawa, Shoko\| Yamamoto, Shumpei\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Kinugasa, Hideaki\| Harada, Keita\| Ohnishi, Hideki\| Okada, Hiroyuki\|
Keywords	bowel wall thickness Mayo endoscopic subscore classification transabdominal ultrasonography ulcerative colitis
Published Date	2022-09-15
Publication Title	Internal Medicine
Volume	volume61
Issue	issue18
Publisher	The Japanese Society of Internal Medicine
Start Page	2703
End Page	2709
ISSN	0918-2918
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	35185047
DOI	10.2169/internalmedicine.8827-21
Web of Science KeyUT	000857218300001
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.8827-21

令和３年度岡山医学会賞　がん研究奨励賞（林原賞・山田賞）

Title Alternative	The 2021 Incentive Award of the Okayama Medical Association in Cancer Research (2021 Hayashibara Prize and Yamada Prize)
Author	Yamasaki, Yasushi\|
Publication Title	Journal of Okayama Medical Association
Published Date	2023-04-01
Volume	volume135
Issue	issue1
Start Page	9
End Page	11
ISSN	0030-1558
Related Url	isVersionOf https://doi.org/10.4044/joma.135.9
language	Japanese
Copyright Holders	Copyright (c) 2023 岡山医学会
File Version	publisher
DOI	10.4044/joma.135.9

Prospective multicenter study of the efficacy and safety of cold forceps polypectomy for ≤ 6-mm non-ampullary duodenal low-grade adenomas

FullText URL	fulltext.pdf
Author	Kanzaki, Hiromitsu\| Horii, Joichiro\| Takenaka, Ryuta\| Nakagawa, Hiroyuki\| Matsueda, Kazuhiro\| Tsuzuki, Takao\| Kita, Masahide\| Yamasaki, Yasushi\| Tanaka, Takehiro\| Iwamuro, Masaya\| Kawano, Seiji\| Kawahara, Yoshiro\| Tomoda, Jun\| Okada, Hiroyuki\|
Published Date	2022-06-10
Publication Title	Endoscopy International Open
Volume	volume10
Issue	issue06
Publisher	Georg Thieme Verlag KG
Start Page	E712
End Page	E718
ISSN	2364-3722
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022. The Author(s).
File Version	publisher
PubMed ID	35859656
DOI	10.1055/a-1793-9439
Web of Science KeyUT	000826506700001
Related Url	isVersionOf https://doi.org/10.1055/a-1793-9439

Fever and electrocoagulation syndrome after colorectal endoscopic submucosal dissection for patients with immunosuppressants and steroids

FullText URL	fulltext.pdf
Author	Yamamoto, Shumpei\| Kinugasa, Hideaki\| Yamasaki, Yasushi\| Hirai, Mami\| Ako, Soichiro\| Takei, Kensuke\| Igawa, Shoko\| Yasutomi, Eriko\| Oka, Shohei\| Ohmori, Masayasu\| Inokuchi, Toshihiro\| Harada, Keita\| Hiraoka, Sakiko\| Nouso, Kazuhiro\| Tanaka, Takehiro\| Okada, Hiroyuki\|
Keywords	colorectal ESD PECS electrocoagulation syndrome immunosuppressants and steroids post-ESD fever
Published Date	2021-12-09
Publication Title	DEN Open
Volume	volume2
Issue	issue1
Publisher	Wiley
Start Page	e83
ISSN	2692-4609
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Authors.
File Version	publisher
PubMed ID	35310725
DOI	10.1002/deo2.83
Web of Science KeyUT	001047024900091
Related Url	isVersionOf https://doi.org/10.1002/deo2.83

Modified line-assisted complete closure of the defect after gastric endoscopic full-thickness resection: a pilot study in porcine models

FullText URL	fulltext.pdf
Author	Yamasaki, Yasushi\| Ohmori, Masayasu\| Toyosawa, Junki\| Ako, Soichiro\| Okada, Hiroyuki\|
Published Date	2022-05-13
Publication Title	Endoscopy International Open
Volume	volume10
Issue	issue05
Publisher	Georg Thieme Verlag KG
Start Page	E609
End Page	E615
ISSN	2364-3722
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022. The Author(s).
File Version	publisher
PubMed ID	35571472
DOI	10.1055/a-1785-8589
Web of Science KeyUT	000794976400010
Related Url	isVersionOf https://doi.org/10.1055/a-1785-8589

Resection depth for small colorectal polyps comparing cold snare polypectomy, hot snare polypectomy and underwater endoscopic mucosal resection

FullText URL	fulltext.pdf
Author	Toyosawa, Junki\| Yamasaki, Yasushi\| Fujimoto, Tsuyoshi\| Tanaka, Shouichi\| Tanaka, Takehiro\| Mitsuhashi, Toshiharu\| Okada, Hiroyuki\|
Published Date	2022-05-13
Publication Title	Endoscopy International Open
Volume	volume10
Issue	issue05
Publisher	Georg Thieme Verlag KG
Start Page	E602
End Page	E608
ISSN	2364-3722
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022. The Author(s).
File Version	publisher
PubMed ID	35571476
DOI	10.1055/a-1785-8616
Web of Science KeyUT	000794976400009
Related Url	isVersionOf https://doi.org/10.1055/a-1785-8616

Berberine improved experimental chronic colitis by regulating interferon-gamma- and IL-17A-producing lamina propria CD4(+) T cells through AMPK activation

FullText URL	SR9_1_11934.pdf
Author	Takahara, Masahiro\| Takaki, Akinobu\| Hiraoka, Sakiko\| Adach, Takuya\| Shimomura, Yasuyuki\| Matsushita, Hiroshi\| Nguyen Tien Thi Thuy\| Koike, Kazuko\| Ikeda, Airi\| Takashima, Shiho\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Kinugasa, Hideaki\| Sugihara, Yusaku\| Harada, Keita\| Eikawa, Shingo\| Morita, Hidetoshi\| Udono, Heiichiro\| Okada, Hiroyuki\|
Published Date	2019-8-15
Publication Title	Scientific Reports
Volume	volume9
Publisher	Nature Publishing Group
Start Page	11934
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2019
File Version	publisher
PubMed ID	31417110
DOI	10.1038/s41598-019-48331-w
Web of Science KeyUT	000480680800048
Related Url	isVersionOf https://doi.org/10.1038/s41598-019-48331-w

Low Patient Weight and Long Intubation Time Are Key Factors for Pain during Colonoscopy

JaLCDOI	10.18926/AMO/65969
FullText URL	77_5_471.pdf
Author	Oka, Shohei\| Harada, Keita\| Yamamoto, Shumpei\| Yasutomi, Eriko\| Igawa, Shoko\| Ohmori, Masayasu\| Hirai, Mami\| Yamasaki, Yasushi\| Inokuchi, Toshihiro\| Kinugasa, Hideaki\| Takahara, Masahiro\| Hiraoka, Sakiko\| Okada, Hiroyuki\|
Abstract	Although the clinical usefulness of colonoscopy has been established, the procedure remains painful for many patients. This study was designed to clarify the factors predicting colonoscopy-related pain. We evaluated 283 consecutive patients who completed a first-ever, total colonoscopy without sedatives or analgesics. The severity of pain symptoms was evaluated by a numeric rating scale (NRS) in a questionnaire immediately after the colonoscopy. Patient backgrounds and endoscopic findings were analyzed to evaluate their association with pain. Out of 283 patients, 53 scored their pain 0-1 on the NRS while 48 scored it 6-10. We defined the colonoscopies of the former and latter patients as painless and painful, respectively, and compared the two. Multivariate analyses revealed that low body weight (OR 4.95, 95%CI 1.89-12.99) and longer intubation time (OR 3.63, 95%CI 1.46-9.03) were significant risk factors for painful colonoscopy. To identify factors contributing to the increased intubation time, we divided subjects into short- and long-intubation-time groups based on a median insertion time of 7 min. Older age (OR 2.28, 95%CI 1.31-3.98), previous abdominal surgery (OR 1.93, 95%CI 1.13-3.32) and findings of invasive cancer (OR 10.90, 95%CI 1.34-88.90) were significant factors for longer intubation time.
Keywords	colonoscopy colonoscopy-related pain comfortable colonoscopy
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2023-10
Volume	volume77
Issue	issue5
Publisher	Okayama University Medical School
Start Page	471
End Page	478
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2023 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	37899258
Web of Science KeyUT	001108661600004

Utility of Combined Use of Transabdominal Ultrasonography and Fecal Immunochemical Test Examinations in Ulcerative Colitis

JaLCDOI	10.18926/AMO/66674
FullText URL	78_1_079.pdf
Author	Takahara, Masahiro\| Hiraoka, Sakiko\| Ohmori, Masayasu\| Takeuchi, Keiko\| Takei, Kensuke\| Aoyama, Yuki\| Yasutomi, Eriko\| Igawa, Shoko\| Inokuchi, Toshihiro\| Toyosawa, Junki\| Yamasaki, Yasushi\| Kinugasa, Hideaki\| Harada, Keita\| Onishi, Hideki\| Okada, Hiroyuki\|
Abstract	This study examined the utility of the combined use of transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis the Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS and FIT were retrospectively enrolled. For TUS, the colon was divided into five segments, and the bowel wall thickness was measured and evaluated. The accuracy of FIT (> 100 ng/ml) in detecting mucosal inflammation (MES>0) was 0.93, whereas that of TUS (BWT>2 mm) in each segment was 0.84-0.97. The combined use of TUS and FIT may be helpful in noninvasive treatment strategies.
Keywords	transabdominal ultrasonography fecal immunochemical test ulcerative colitis Mayo endoscopic subscore
Amo Type	Short Communication
Publication Title	Acta Medica Okayama
Published Date	2024-02
Volume	volume78
Issue	issue1
Publisher	Okayama University Medical School
Start Page	79
End Page	83
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2024 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	38419318