result 312 件
FullText URL | fulltext.pdf |
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Author | Nakano, Ryohei| Kawai, Takashi| Fukamatsu, Yosuke| Akita, Kagari| Watanabe, Sakine| Asano, Takahiro| Takata, Daisuke| Sato, Mamoru| Fukuda, Fumio| Ushijima, Koichiro| |
Keywords | fruit softening ethylene Prunus persica melting flesh locus endoPG postharvest |
Published Date | 2020-11-26 |
Publication Title | Frontiers in Plant Science |
Volume | volume11 |
Publisher | Frontiers Media |
Start Page | 554158 |
ISSN | 1664-462X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 Nakano, Kawai, Fukamatsu, Akita, Watanabe, Asano, Takata, Sato, Fukuda and Ushijima. |
File Version | publisher |
PubMed ID | 33324428 |
DOI | 10.3389/fpls.2020.554158 |
Web of Science KeyUT | 000596841900001 |
Related Url | isVersionOf https://doi.org/10.3389/fpls.2020.554158 |
FullText URL | fulltext.pdf |
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Author | Abe, Koji| Shang, Jingwei| Shi, Xiaowen| Yamashita, Toru| Hishikawa, Nozomi| Takemoto, Mami| Morihara, Ryuta| Nakano, Yumiko| Ohta, Yasuyuki| Deguchi, Kentaro| Ikeda, Masaki| Ikeda, Yoshio| Okamoto, Koichi| Shoji, Mikio| Takatama, Masamitsu| Kojo, Motohisa| Kuroda, Takeshi| Ono, Kenjiro| Kimura, Noriyuki| Matsubara, Etsuro| Osakada, Yosuke| Wakutani, Yosuke| Takao, Yoshiki| Higashi, Yasuto| Asada, Kyoichi| Senga, Takehito| Lee, Lyang-Ja| Tanaka, Kenji| |
Keywords | Alzheimer’s disease biomarker coagulation complement MALDI-TOF mild cognitive impairment neuroinflammation peptidome plasticity |
Published Date | 2020-01-07 |
Publication Title | Journal of Alzheimer's Disease |
Volume | volume73 |
Issue | issue1 |
Publisher | IOP Press |
Start Page | 217 |
End Page | 227 |
ISSN | 1387-2877 |
NCID | AA11545428 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 - IOS Press and the authors. |
File Version | publisher |
PubMed ID | 31771070 |
DOI | 10.3233/JAD-191016 |
Web of Science KeyUT | 000506311500018 |
Related Url | isVersionOf https://content.iospress.com/articles/journal-of-alzheimers-disease/jad191016 |
JaLCDOI | 10.18926/AMO/61212 |
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FullText URL | 74_6_525.pdf |
Author | Aoki, Hideki| Utsumi, Masashi| Kimura, Yuji| Takahashi, Yosuke| Nagahisa, Seiichi| Nishimura, Seitaro| Une, Yuta| Watanabe, Megumi| Taniguchi, Fumitaka| Arata, Takashi| Katsuda, Koh| Tanakaya, Kohji| |
Abstract | Cardiac metastasis originating from hepatocellular carcinoma (HCC) is a rare condition with a poor prognosis. No therapeutic standards for cardiac metastasis originating from HCC have been established. At 19 months after a curative hepatectomy, a 64-year-old Japanese hepatitis B virus-positive male patient experienced solitary cardiac metastasis originating from HCC. The cardiac tumor was discovered in the right ventricle. The patient received three courses of radiotherapy and chemotherapy and survived > 3 years after the initial diagnosis of cardiac metastasis. His case demonstrates that radiotherapy combined with chemotherapy can be an effective treatment for cardiac metastasis. |
Keywords | hepatocellular carcinoma cardiac metastasis radiotherapy chemotherapy |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2020-12 |
Volume | volume74 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 525 |
End Page | 530 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 33361873 |
Web of Science KeyUT | 000601203600009 |
NAID | 120006948951 |
FullText URL | fulltext.pdf |
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Author | Takabatake, Kiyofumi| Tsujigiwa, Hidetsugu| Nakano, Keisuke| Inada, Yasunori| Qiusheng, Shan| Kawai, Hotaka| Sukegawa, Shintaro | Fushimi, Shigeko| Nagatsuka, Hitoshi| |
Keywords | dental pulp honeycomb TCP matrix formation dentin formation geometrical structure scaffold |
Published Date | 2020-11-16 |
Publication Title | Materials |
Volume | volume13 |
Issue | issue22 |
Publisher | MDPI |
Start Page | 5155 |
ISSN | 1996-1944 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 33207665 |
DOI | 10.3390/ma13225155 |
Web of Science KeyUT | 000594220200001 |
Related Url | isVersionOf https://doi.org/10.3390/ma13225155 |
FullText URL | fulltext.pdf |
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Author | Jiao, Yu Yang| Okada, Masahiro| Hara, Emilio Satoshi| Xie, Shi Chao| Nagaoka, Noriyuki| Nakano, Takayoshi| Matsumoto, Takuya| |
Keywords | bone-like material mechanical property orientation layered structure |
Published Date | 2020-11-12 |
Publication Title | Materials |
Volume | volume13 |
Issue | issue22 |
Publisher | MDPI |
Start Page | 5099 |
ISSN | 1996-1944 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 33198178 |
DOI | 10.3390/ma13225099 |
Web of Science KeyUT | 000594906000001 |
Related Url | isVersionOf https://doi.org/10.3390/ma13225099 |
FullText URL | fulltext.pdf |
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Author | Yamamoto, Norio| Sukegawa, Shintaro | Kitamura, Akira| Goto, Ryosuke| Noda, Tomoyuki| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Nagatsuka, Hitoshi| Kawasaki, Keisuke| Furuki, Yoshihiko| Ozaki, Toshifumi| |
Keywords | osteoporosis deep learning hip radiograph ensemble model |
Published Date | 2020-11-10 |
Publication Title | Biomolecules |
Volume | volume10 |
Issue | issue11 |
Publisher | MDPI |
Start Page | 1534 |
ISSN | 2218-273X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 33182778 |
DOI | 10.3390/biom10111534 |
Web of Science KeyUT | 000592980100001 |
Related Url | isVersionOf https://doi.org/10.3390/biom10111534 |
FullText URL | fulltext.pdf |
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Author | Watanabe, Toshiyuki| Takabatake, Kiyofumi| Tsujigiwa, Hidetsugu| Watanabe, Satoko| Nakagiri, Ryoko| Nakano, Keisuke| Nagatsuka, Hitoshi| Kimata, Yoshihiro| |
Keywords | honeycomb β-TCP bone tissue regeneration bone microenvironment Vertical and Horizontal holes geometrical structure |
Published Date | 2020-10-25 |
Publication Title | Materials |
Volume | volume13 |
Issue | issue21 |
Publisher | MDPI |
Start Page | 4761 |
ISSN | 1996-1944 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 33113818 |
DOI | 10.3390/ma13214761 |
Web of Science KeyUT | 000589377800001 |
Related Url | isVersionOf https://doi.org/10.3390/ma13214761 |
FullText URL | fulltext.pdf |
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Author | Takabatake, Kiyofumi| Kawai, Hotaka| Omori, Haruka| Qiusheng, Shan| Oo, May Wathone| Sukegawa, Shintaro | Nakano, Keisuke| Tsujigiwa, Hidetsugu| Nagatsuka, Hitoshi| |
Keywords | tumor stroma tumor parenchyma tumor microenvironment biological characteristics |
Published Date | 2020-10-18 |
Publication Title | International Journal of Molecular Sciences |
Volume | volume21 |
Issue | issue20 |
Publisher | MDPI |
Start Page | 7714 |
ISSN | 1422-0067 |
NCID | AA12038549 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 33081066 |
DOI | 10.3390/ijms21207714 |
Web of Science KeyUT | 000585565900001 |
Related Url | isVersionOf https://doi.org/10.3390/ijms21207714 |
JaLCDOI | 10.18926/AMO/60796 |
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FullText URL | 74_5_371.pdf |
Author | Makimoto, Go| Ohashi, Kadoaki| Maeda, Yoshinobu| Kiura, Katsuyuki| |
Abstract | The prognosis of advanced non-small cell lung cancer (NSCLC) patients has improved in recent decades, especially for patients with an oncogenic driver mutation. Anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) are effective for patients with the echinoderm microtubule-associated protein-like 4-ALK fusion gene. Several ALK-TKIs have been established: the first-generation ALK-TKI, crizotinib; second-generation ALK-TKIs, alectinib and ceritinib; and third-generation ALK-TKI, lorlatinib. Some ALK-TKIs are effective for tumors that are resistant to other ALK-TKIs; however, as is known in epidermal growth factor receptormutant lung cancer, tumor resistance is inevitable. ALK-positive NSCLCs acquire resistance via various mechanisms, making it a heterogeneous disease. Therefore, it is necessary to develop next-generation treatment strategies, such as the use of next-generation ALK-TKIs for secondary mutations, or combination therapies with ALK-TKIs and other TKIs. In this review, we summarize the development and use of ALK-TKIs, prior pivotal clinical trials, and resistance mechanisms. |
Keywords | lung cancer anaplastic lymphoma kinase tyrosine kinase inhibitors resistance mechanism |
Amo Type | Review |
Publication Title | Acta Medica Okayama |
Published Date | 2020-10 |
Volume | volume74 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 371 |
End Page | 379 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 33106692 |
Web of Science KeyUT | 000581970100001 |
NAID | 120006892922 |
FullText URL | fulltext.pdf |
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Author | Sukegawa, Shintaro | Ono, Sawako| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Nagatsuka, Hitoshi| Furuki, Yoshihiko| |
Keywords | Cytology Pathology Liquid-based cytology Screening Inflammation |
Published Date | 2020-09-10 |
Publication Title | Diagnostic Pathology |
Volume | volume15 |
Issue | issue1 |
Publisher | BMC |
Start Page | 107 |
ISSN | 1746-1596 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s). 2020 |
File Version | publisher |
PubMed ID | 32912249 |
DOI | 10.1186/s13000-020-01027-6 |
Web of Science KeyUT | 000570651500001 |
Related Url | isVersionOf https://doi.org/10.1186/s13000-020-01027-6 |
FullText URL | InternMed_59_2067_2070.pdf |
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Author | Fukushima, Shinnosuke| Hagiya, Hideharu| Mizuta, Yuki| Nakano, Yasuhiro| Takahara, Masahiro| Okamoto, Kayo| Hayashi, Yuko| Yamada, Kiyoshi| Hasegawa, Kou| Otsuka, Fumio| |
Keywords | dentofacial abscesses odontogenic infection osteomyelitis multidrug resistance viridans Streptococcus |
Published Date | 2020-08-15 |
Publication Title | Internal Medicine |
Volume | volume59 |
Issue | issue16 |
Publisher | The Japanese Society of Internal Medicine |
Start Page | 2067 |
End Page | 2070 |
ISSN | 0918-2918 |
NCID | AA10827774 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | publisher |
PubMed ID | 32389944 |
NAID | 130007887682 |
DOI | 10.2169/internalmedicine.4283-20 |
Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.4283-20 |
FullText URL | fulltext.pdf |
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Author | Kodama, Matsuri| Higuchi, Hitoshi| Ishii-Maruhama, Minako| Nakano, Mai| Honda-Wakasugi, Yuka| Maeda, Shigeru| Miyawaki, Takuya| |
Keywords | Drug regulation Phase IV trials |
Published Date | 2020-01-31 |
Publication Title | Scientific Reports |
Volume | volume10 |
Issue | issue1 |
Publisher | Nature |
Start Page | 1578 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2020 |
File Version | publisher |
PubMed ID | 32005870 |
DOI | 10.1038/s41598-020-58460-2 |
Web of Science KeyUT | 000562877500004 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-020-58460-2 |
Title Alternative | For Interaction with Muslim International Students: From View Point of Japanese Commonality on Case and Practical Studies |
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FullText URL | ryugakukouryuu_100.pdf |
Author | Nakano, Sachiko| Tanaka, Tomoko| |
Keywords | 在日ムスリム留学生 異文化交流 |
Published Date | 2019-07 |
Publication Title | 留学交流 |
Volume | volume100 |
Publisher | 日本学生支援機構 |
Start Page | 32 |
End Page | 43 |
ISSN | 0916-1309 |
NCID | AN10095893 |
Content Type | Journal Article |
language | Japanese |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © JASSO |
File Version | publisher |
Official Url | https://www.jasso.go.jp/ryugaku/related/kouryu/2019/07.html| |
Related Url | isVersionOf https://www.jasso.go.jp/ryugaku/related/kouryu/2019/__icsFiles/afieldfile/2019/07/09/201907nakanotanaka.pdf |
FullText URL | fulltext.pdf |
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Author | Kohara, Keigo| Inoue, Akitoshi| Nakano, Yousuke| Hirai, Hirokazu| Kobayashi, Takuya| Maruyama, Masato| Baba, Ryosuke| Kawashima, Chiho| |
Published Date | 2020-06-26 |
Publication Title | iScience |
Volume | volume23 |
Issue | issue6 |
Publisher | Cell Press |
Start Page | 101248 |
ISSN | 25890042 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Author(s). |
File Version | publisher |
DOI | 10.1016/j.isci.2020.101248 |
Related Url | isVersionOf |
JaLCDOI | 10.18926/AMO/60376 |
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FullText URL | 74_4_365.pdf |
Author | Chuma, Masayuki| Kondo, Masateru| Zamami, Yoshito| Takechi, Kenshi| Goda, Mitsuhiro| Okada, Naoto| Shibata, Akitomo| Asada, Mizuho| Oto, Jun| Yanagawa, Hiroaki| Ishizawa, Keisuke| |
Abstract | Cystatin C-guided vancomycin (VCM) dosing is useful in critically ill patients. Its usefulness in septic patients with bacterial meningitis remains unknown, as there are no published reports. In this study, we sought to clarify its benefit. Cystatin C was used to guide VCM dosing in a septic bacterial meningitis patient with normal kidney function, according to therapeutic drug monitoring (TDM). Using cystatin C, the Bayesian method-based TDM made optimal VCM dosing possible, and decreased the predicted error (4.85 mg/L) compared to serum creatinine (16.83 mg/L). We concluded TDM of VCM using cystatin C can be considered in sepsis patients with bacterial meningitis with normal kidney function. |
Keywords | vancomycin, therapeutic drug monitoring cystatin C bacterial meningitis sepsis |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2020-08 |
Volume | volume74 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 365 |
End Page | 370 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32843769 |
Web of Science KeyUT | 000562508700013 |
NAID | 120006880215 |
JaLCDOI | 10.18926/AMO/60372 |
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FullText URL | 74_4_335.pdf |
Author | Yamamoto, Yumiko| Hayashi, Yoshihiro| Murakami, Ichiro| |
Abstract | Since the discovery of the NAB2-STAT6 gene fusion in 2013, solitary fibrous tumor (SFT) and hemangiopericytoma (HPC) have been considered the same disease. STAT6 nuclear stain is approved as a highly sensitive and specific marker to diagnose SFT/HPC from other tumors with similar histology. As the next step, detection of fusion variants that may predict clinical malignancy of SFT/HPC has been attempted. However, no fusion variants with a clear relation to malignancy have been identified. In this study, the clinical and histological backgrounds of 23 Japanese patients diagnosed with SFT/HPC from 2000 to 2019 at Kochi University Hospital were examined to identify factors potentially related to recurrence. A significant relationship to recurrence was detected for mitosis ≥ 1/10 HPF (400×), necrosis, and Ki-67>5%. These findings indicate that a deliberate investigation of histological features such as mitosis and necrosis is crucial for the clinical observation of SFT/ HPC patients. In addition, Ki-67 was revealed to be a useful parameter to predict recurrence in SFT/HPC patients. |
Keywords | solitary fibrous tumor hemangiopericytoma Ki-67 NAB2-STAT6 WHO classification WHO grading criteria Marseille Grading System |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-08 |
Volume | volume74 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 335 |
End Page | 343 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32843765 |
Web of Science KeyUT | 000562508700009 |
NAID | 120006880211 |
FullText URL | fulltext.pdf |
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Author | Morikawa, Yuko| Morimoto, Setsuyo| Yoshida, Eri| Naka, Shuhei| Inaba, Hiroaki| Matsumoto-Nakano, Michiyo| |
Keywords | Streptococcus mutans glutamine transporter biofilm membrane protein glnP |
Published Date | 2020-08-04 |
Publication Title | Journal of Oral Microbiology |
Volume | volume12 |
Issue | issue1 |
Publisher | Taylor & Francis |
Start Page | 1797320 |
ISSN | 2000-2297 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Author(s). |
File Version | publisher |
DOI | 10.1080/20002297.2020.1797320 |
Web of Science KeyUT | 000555592200001 |
Related Url | isVersionOf https://doi.org/10.1080/20002297.2020.1797320 |
FullText URL | fulltext.pdf |
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Author | Sukegawa, Shintaro | Yoshii, Kazumasa| Hara, Takeshi| Yamashita, Katsusuke| Nakano, Keisuke| Yamamoto, Norio| Nagatsuka, Hitoshi| Furuki, Yoshihiko| |
Keywords | dental implant artificial intelligence classification deep learning convolutional neural networks |
Published Date | 2020-07-01 |
Publication Title | Biomolecules |
Volume | volume10 |
Issue | issue7 |
Publisher | MDPI |
Start Page | 984 |
ISSN | 2218-273X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32630195 |
DOI | 10.3390/biom10070984 |
Web of Science KeyUT | 000554759800001 |
Related Url | isVersionOf https://doi.org/10.3390/biom10070984 |
FullText URL | fulltext.pdf |
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Author | Misawa, Masaaki| Fukushima, Shogo| Koura, Akihide| Shimamura, Kohei| Shimojo, Fuyuki| Tiwari, Subodh| Nomura, Ken-ichi| Kalia, Rajiv K.| Nakano, Aiichiro| Vashishta, Priya| |
Note | This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Physical Chemistry Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.jpclett.0c00637.| |
Published Date | 2020-05-22 |
Publication Title | Journal of Physical Chemistry Letters |
Volume | volume11 |
Issue | issue11 |
Publisher | American Chemical Society |
Start Page | 4536 |
End Page | 4541 |
ISSN | 1948-7185 |
NCID | AA1260018X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 32443935 |
DOI | 10.1021/acs.jpclett.0c00637 |
Web of Science KeyUT | 000538759600044 |
Related Url | isVersionOf https://doi.org/10.1021/acs.jpclett.0c00637 |
JaLCDOI | 10.18926/AMO/59954 |
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FullText URL | 74_3_221.pdf |
Author | Yagura, Takuma| Oe, Kenichi| Paku, Masaaki| Tajima, Takeshi| Nakamura, Masaya| Iida, Hirokazu| Saito, Takanori| |
Abstract | We retrospectively evaluated the cases of 169 hip fracture patients, their previous fractures, and the contralateral hip joint’s morphology. A history of contralateral hip fracture was present in 23 patients (Contra group). The other patients had a unilateral hip fracture: a trochanteric fracture (Troch group, n=73) or a femoral neck fracture (Neck group, n=73). In the Troch and Neck groups, we used anteroposterior and cross-table axialview radiographs of the contralateral hip to evaluate the proximal femur’s anatomy. In the Contra group, the concordance rate between the first and second types of hip fracture was 65.2%, and the second hip fracture’s morphology indicated that the trochanteric fracture had a cam deformity in terms of the femoral head-neck ratio. The average alpha angle and femoral head-neck offset in the Troch group were significantly larger than those in the Neck group. In the Neck group, pistol-grip deformities of Arbeitsgemeinschaft für Osteosynthesefragen types B1 (subcapital), B2 (transcervical), and B3 (displaced) were observed in 42.1%, 75%, and 6% of cases, respectively. There was a smaller alpha angle and a larger femoral head-neck offset in the contralateral hip of femoral neck fractures; thus, the “cam deformity” may protect against femoral neck fractures. |
Keywords | cam deformity femoral neck fracture trochanteric fracture bilateral hip fractures |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-06 |
Volume | volume74 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 221 |
End Page | 227 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32577020 |
Web of Science KeyUT | 000543363400006 |
NAID | 120006862796 |