result 1489 件
| JaLCDOI | 10.18926/21115 |
|---|---|
| Title Alternative | Hypnotic effect of the peloid therapy applied on the right hypochondrium in reference to plasma L-tryptophan |
| FullText URL | pitsr_053_009_011.pdf |
| Author | Morinaga, Hiroshi| Komoto, Junko| Komoto, Yoshiaki| |
| Abstract | Based on the EEG-observation of falling asleep when patients are under peloid therapy applied on the right hypochondrium, following assumption is made to clarify the mechanism of inducing sleep. While patients are under the peloid therapy, some chemical substance will be produced in circulating blood; L-tryptophan, an essential amino acid and a precursor of serotonin, gets over a blood-brain barrier easily to induce sleep. Six healthy volunteers, each sex by threes, were selected to apply peloid pack on the right hypochondrium for 30 minutes following 12-hour fasting. Significant increase in plasma L-tryptophan level was obtained in the clinical experiment. It is speculated from the preliminary data that L-tryptophan increased by the peloid therapy may possibly act as a specific physiological hypnotics. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1983-03-25 |
| Volume | volume53 |
| Start Page | 9 |
| End Page | 11 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002311031 |
| JaLCDOI | 10.18926/21114 |
|---|---|
| Title Alternative | Determination of ferritin in serum and in synovial fluids of patients with rheumatoid arthritis |
| FullText URL | pitsr_053_001_008.pdf |
| Author | Furuno, Katsushi| Morinaga, Hiroshi| Irino, Shozo| |
| Abstract | Ferritin in sera and in synovial fluids were determined by method of immunoradiometric assay (IRMA) and of radioimmunoassay (RIA). These methods have been proved to be reproducible. The coefficient variation was 7.4 to 9.9% in IRMA and 5.6 to 8.0% in RIA. There were a good correlation between methods of IRMA and of RIA (r=0.989). The mean recovery rate of ferritin in serum was 101.2% in IRMA and 101.0% in RIA, respectively. The determination of serum ferritin revealed a 16% reduction in average after preservation at -20℃ during over 100 days. The levels of serum ferritin in healthy controls were 131.4±52.1 ng/ml in 34 males and 58.4±39.9 ng/ml in 38 females. The sex differences were statisticalIy significant (p<0.01). Ferritin levels were shown to be below 30 ng/ml (the state of iron deficiency) in 2 of 34 (5.9%) males and in 8 of 38 (21%) females of healthy controls. The levels of serum ferritin in patients with rheumatoid arthritis (RA) were 337.0±293.4ng/ml in 10 males and 181.4±329.9ng/ml in 25 females. The serum ferritin in RA was significantly higher than in healthy controls of both sexes. The levels of ferritin in synovial fluids of patients with 14 RA and with 12 osteoarthritis were 2894±3017 ng/ml and 1429±1005 ng/ml, and no differences were observed in both groups. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1983-03-25 |
| Volume | volume53 |
| Start Page | 1 |
| End Page | 8 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002311016 |
| JaLCDOI | 10.18926/21106 |
|---|---|
| Title Alternative | 好塩基球からのヒスタミン遊離に関する研究. 3. 抗ヒトIgE に対する好塩基球の反応性と末梢血好酸球増多 |
| FullText URL | pitsr_054_035_038.pdf |
| Author | Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Mifune, Masaaki| Morinaga, Hiroshi| Nakagawa, Saburo| Kitani, Hikaru| Kimura, Ikuro| |
| Abstract | Histamine release from basophils induced by anti-IgE was examined in 14 asthmatic subjects with blood eosinophilia. The subjects were divided into two groups; group I (with blood eosinophilia, positive skin test and positive RAST to house dust) and group II (with blood eosinophilia, negative skin test to various allergens and negative RAST to house dust). 1. Serum IgE levels in group I were much higher than those in group II. 2. Maximum percent histamine release induced by anti-IgE was much higher in group I than in group II. 3. Dose-response curve of anti-IgE-induced histamine release in group I showed consistent increase as anti-IgE concentrations increased. while, dose-response curve in group II was very low. These findings suggested that blood eosinophilia in group I might be elicited relating to IgE-mediated reaction. However, mechanism causing eosinophilia in group II was not clear in the present study. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1984-03-25 |
| Volume | volume54 |
| Start Page | 35 |
| End Page | 38 |
| ISSN | 0369-7142 |
| language | English |
| File Version | publisher |
| NAID | 120002310989 |
| JaLCDOI | 10.18926/21104 |
|---|---|
| Title Alternative | Effects of serial bathing on fatty acid composition of adrenal and serum cholesterol ester in rats |
| FullText URL | pitsr_054_019_024.pdf |
| Author | Seno, Toshinobu| Harada, Hideo| Mifune, Masaaki| Morinaga, Hiroshi| |
| Abstract | The effects of serial bathing (10 minutes bathing in a city water or hot spring in Misasa, 40℃, once daily for 1-4 weeks) on fatty acid composition of cholesterol ester of the adrenal glands and serum was studied in both normal and hypercholesteremic rats. Although the adrenal cholesterol ester levels were relatively unaffected in rats treated with serial bathing as well as non-treated rats, the proportion of 18 : 2 was increased in rats treated with hot spring bathing for 3-4 weeks. The serum cholesterol ester levels in both normal and hypercholesteremic rats tended to decrease after serial bathing for 3-4 weeks compared with non-treated rats. The fatty acid composition of serum cholesterol ester in normal rats was unaffected. The composition in hypercholesteremic rats showed an increase in the proportion of 16 : 1 and 18 : 1 and a decrease of 18 : 2 and 20: 4 compared with normal rats. When those of hypercholesteremic rats were treated with serial bathing for 3 weeks, particularly with hot spring bathing, the proportion of 16 : 1, 18: 2 and 20 : 4 showed a tendency to approach that in tormal rats. The findings indicate that serial hot spring bathing for 3-4 weeks, unlike city water bathing, exerts an influence on the fatty acid composition of cholesterol ester of the rat adrenal glands and it also improves the fatty acid compsition of serum cholesterolester of hypercholesteremic rats. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1984-03-25 |
| Volume | volume54 |
| Start Page | 19 |
| End Page | 24 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002310999 |
| JaLCDOI | 10.18926/21103 |
|---|---|
| Title Alternative | Effects of swimming training in the hot spring pool on ventilatory function in bronchial asthma |
| FullText URL | pitsr_054_013_018.pdf |
| Author | Sudo, Michiyasu| Komagoe, Haruki| Okada, Chiharu| Nakago, Jitsuo| Tanizaki, Yoshiro| Morinaga, Hiroshi| |
| Abstract | Effect of free swimming training in the hot spring pool (30℃) on ventilatory function were observed in nine patients with intractable asthma by measuring FVC, FEV(1.0), PEFR, MMF, V(50), V(25). 1. Swimming in the hot spring pool for three months allowed the reduction of glucocorticoid used for their asthma attack. 2. Although FVC was not affected by swimming training, EEV(1.0), PEFR, MMF, V(50), V(25) which represent obstructive ventilatory function were gradually improved by swimming training. The results show that free swimming training in the hot springpool is clinically available in intractable asthma. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1984-03-25 |
| Volume | volume54 |
| Start Page | 13 |
| End Page | 18 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002310964 |
| JaLCDOI | 10.18926/21102 |
|---|---|
| Title Alternative | Research for carbon dioxide bathing IV, Thermal effect of artificial CO(2)-bathing |
| FullText URL | 054_001_012.pdf |
| Author | Yorozu, Hidenori| Kubo, Yuichiro| Eguchi, Yasuteru| Sunakawa, Mitsuru| Kohmoto, Tomoji| Komoto, Yoshiaki| Komoto, ]unko| |
| Abstract | 1) 炭酸塩と,コ-ク酸からなる錠剤型の｢炭酸ガス浴剤｣の保温作用を健康な男子8名について,サ-モグラフィーを用いて測定した. 入浴10分後の比較で明らかに,炭酸ガス浴はよく温まった結果,表面温度が高くなっている. 2) 腰痛,四肢冷感,その他の患者24名での臨床評価の結果,患者の90%以上が手足が温まり,湯ざめしにくいことを認めた.また,患者の85%は痛みがやわらぐことを認めた. 3) 主婦664名を対象とした使用評価の結果,常時手足の冷感を訴える者の63.6%,身体の疲労感･だるさ56.5%に効果を認めていることがわかった. 4) 副作用は全く認められなかった. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1984-03-25 |
| Volume | volume54 |
| Start Page | 1 |
| End Page | 12 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| Author | Inoue, Taeko| Tanizaki, Yoshiro| Morinaga, Hiroshi| |
|---|---|
| Published Date | 1984-11-30 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume55 |
| Content Type | Data or Dataset |
| JaLCDOI | 10.18926/21086 |
|---|---|
| Title Alternative | Effect of serial bathing on circadian variation of plasma metabolites in rats |
| FullText URL | pitsr_056_035_043.pdf |
| Author | Seno, Toshinobu| Harada, Hideo| Mifune, Masaaki| Morinaga, Hiroshi| |
| Abstract | The effect of serial bathing (10-minute bathing in city water or Misasa hot spring, 40℃, once daily for one or four weeks) on the circadian variations of plasma metabolites was studied in three groups of rats : hot spring bathing rats, city water bathing rats and non-treated rats. Plasma obtained by decapitation at 8:00, 12:00, 16:00, 20:00 and 24:00 hours was analysed for catecholamines (CA), free fatty acids (FFA), cholesterol (C) and glucose. 1) Noradrenaline (NA) and adrenaline (A) were significantly lower at 24:00 hours with significantly lower 24-hour average concentrations and also with significantly different diurnal patterns in the 1-week hot spring bathing rats; in the 4-week hot spring bathing rats, lower 24-hour average concentrarion of A was the only significant finding. The results suggest the suppressive effect of hot spring bathing on the sympathetic system or pituitary gland-adrenal medulla; they also suggest the adaptation to hot spring bathing. 2) Free fatty acids were significantly higher in the 1-week hot spring bathing rats at 12:00 hours as compared with non-treated rats and city water bathing rats. The 4-week hot spring bathing rats showed concentration of FFA not different from the remaining two groups of rats. No significant difference was noted in diurnal patterns among the three groups of rats. The results suggest that the high FFA concentrations in the 1-week hot spring bathing rats are related to the physico-chemical constituents of the hot spring to some extent and that the rats adapt themselves to bathing during the 4-week preriod. 3) Cholesterol was significantly lower in the 4-week hot spring bathing rats as compared with non-treated rats and city water bathing rats; no different diurnal patterns were noted among the three groups of rats. The results suggest the suppressive effect of 4-week hot spring bathing on plasma cholesterol concentrations as reported previously by us. 4) No Significant difference was noted in concentrations as well as in diurnal patterns of plasma glucose among the three groups of rats. The results suggest that bathing has no significan effect on concentrations and diurnal patterns of plasma glucose in healthy rats. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1985-03-30 |
| Volume | volume56 |
| Start Page | 35 |
| End Page | 43 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002310969 |
| JaLCDOI | 10.18926/21082 |
|---|---|
| Title Alternative | The effect on tissue perfusion by brine spring (solquellen) |
| FullText URL | pitsr_056_013_016.pdf |
| Author | Komoto, Yoshiaki| Kohmoto, Tomoji| Sunakawa, Mitsuru| Komoto, Junko| |
| Abstract | Changes in partial pressures of each tissue gas and tissue perfusion were evaluated in the 2.5% artificial salt baths by means of medical mass spectrometry using 9 rabbits. The level of subcutaueous PO(2) lowered by 18% and PCO(2) elevated by 7 % compared with the plain water bath. The tissue perfusion volume was found increased by few %. It is assumed that we owe the warm feeling after taking concentrated salt baths to the improved tissue perfusion. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1985-03-30 |
| Volume | volume56 |
| Start Page | 13 |
| End Page | 16 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002311012 |
| JaLCDOI | 10.18926/21081 |
|---|---|
| Title Alternative | An application of the artificial CO(2) bath for enuresis |
| FullText URL | pitsr_056_009_011.pdf |
| Author | Komoto, Junko| Komoto, Yoshiaki| |
| Abstract | The artificial CO(2) bath was prescribed for two enuretic boys with bladder-sensitive or parasympaticotonic type. A tablet of 50 g, made from sodium bicarbonate and succinic acid, was put in a bath-tub of 150-200 L at 40℃. Each patient was recommended to take a bath with his mother longer than ten minutes, and to mark the presence or the absence of enuresis every day. Outcome results of case 1 on CO(2) bath is shown in tabel 1 and results of case 2 on CO(2) bath is shown in table 3. Both two cases became free from enuresis 7-10 days after the initiation of the artificial CO(2) bathing. Etiological mechanisms of enuresis seem to be multi-factorious, with underlining networks of central- and autonomous nerve systems for the control of sleep and bladder. It is suspected that some improvement of peripheral circulation by CO(2)-bathing leading to keep the body warm may be one of the contributing factors which prolong the intervals of urination, resulting in autonomous normalization, at least, for the cases of bladder-sensitive enuresis, Further case studies are needed to support this assumption. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1985-03-30 |
| Volume | volume56 |
| Start Page | 9 |
| End Page | 11 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002310958 |
| JaLCDOI | 10.18926/21080 |
|---|---|
| Title Alternative | A case of psychogenic fever |
| FullText URL | 056_005_008.pdf |
| Author | Komoto, Junko| Yasumoto, Ikuko| |
| Abstract | An 18 years old girl, who developed high fever following sore throat without demonstrable organic findings, was diagnosed as having psychogenic fever. Symptom was apparently related to her psychological conflicts in an unconscious pursuit of both the primary gain (avoidance to take examination for college) and the secondary gain (satisfaction for dependancy-need). Initiation, exacerbation and termination of fever were not under voluntary control but produced by self-induced hypnosis. Details of her hypnotic process together with her insight into the condition after psychotherapy were described as clinical data. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1985-03-30 |
| Volume | volume56 |
| Start Page | 5 |
| End Page | 8 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| JaLCDOI | 10.18926/21079 |
|---|---|
| Title Alternative | Radioactivity and chromosome aberrations of residents of Misasa Spa |
| FullText URL | pitsr_056_001_004.pdf |
| Author | Morinaga, Hiroshi| Mifune, Masaaki| Furuno, Katsuaki| |
| Abstract | Misasa Spa is one of the most highly radioactive hot springs in Japan, the waters of which contain mainly (222)Rn (437±132 Bq/liter). Radon contents of indoor air of private houses and health resort hotels (built of wood) at Misasa Spa range from 18.5 to 55.5 mBq/liter and 22.2 to 129.5 mBq/liter, respectively. Radon contents in the air of facilities using spring waters at Misasa Branch Hospital of Okayama University were measured to be ; bathroom 807±78 mBq/liter; Hubbardtank bathroom 5306±2568 mBq/liter ; the drinking hall 1491±178 mBq/liter. The environmental and dose rate inside private houses has been measured to be 14.0±1.8 μR/h. Chromosome aberrations (dicentrics) in the peripheral blood lymphocytes of residents of Misasa Spa were investigated in 14 persons; the mean value of aberration frequencies were 0.21%. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1985-03-30 |
| Volume | volume56 |
| Start Page | 1 |
| End Page | 4 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002311024 |
| Author | Institute for Environmental Medicine, Okayama University Medical Scool| |
|---|---|
| Published Date | 1986-07 |
| Publication Title | 環境病態研報告 |
| Volume | volume57 |
| Content Type | Others |
| Author | Institute for Environmental Medicine, Okayama University Medical Scool| |
|---|---|
| Published Date | 1986-07 |
| Publication Title | 環境病態研報告 |
| Volume | volume57 |
| Content Type | Others |
| Author | Institute for Environmental Medicine, Okayama University Medical Scool| |
|---|---|
| Published Date | 1986-07 |
| Publication Title | 環境病態研報告 |
| Volume | volume57 |
| Content Type | Others |
| Author | Institute for Environmental Medicine, Okayama University Medical Scool| |
|---|---|
| Published Date | 1986-07 |
| Publication Title | 環境病態研報告 |
| Volume | volume57 |
| Content Type | Others |
| Author | Institute for Environmental Medicine, Okayama University Medical Scool| |
|---|---|
| Published Date | 1986-07 |
| Publication Title | 環境病態研報告 |
| Volume | volume57 |
| Content Type | Others |
| Author | 森永 寛| |
|---|---|
| Published Date | 1986-07 |
| Publication Title | 環境病態研報告 |
| Volume | volume57 |
| Content Type | Others |
| Author | 小田 琢三| |
|---|---|
| Published Date | 1986-07 |
| Publication Title | 環境病態研報告 |
| Volume | volume57 |
| Content Type | Others |
| Author | Institute for Environmental Medicine, Okayama University Medical Scool| |
|---|---|
| Published Date | 1986-07 |
| Publication Title | 環境病態研報告 |
| Volume | volume57 |
| Content Type | Others |
