result 47501 件
| JaLCDOI | 10.18926/15335 |
|---|---|
| Title Alternative | Physical therapy of patients with total hysterectomy |
| FullText URL | 063_106_109.pdf |
| Author | Kamimoto, Manabu| Okuda, Hiroyuki| Tanizaki, Yoshiro| |
| Abstract | 子宮全摘術を受け,回復期に理学療法を実施した患者に,自転車エルゴメーターによる同一負荷運動時の心拍数について施行前と退院時の変化を検討した｡その結果,退院時に心拍数は有意に減少した｡しかし,その減少の程度は理学療法実施回数と相関しなかった｡患者は水中運動を積極的に実施し,速やかに家庭生活を含めた社会生活への復帰が可能となった｡退院後の外来診察時に異常も認められず,理学療法の有効性並びに安全性が確認された。 |
| Keywords | 子宮全摘術 (Abdominal hysterectomy) 術後理学療法 (Postoperative Physical therapy) 自転車エルゴメーター (Bicycle ergometer) 心拍数 (Heart rate) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 106 |
| End Page | 109 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307203 |
| JaLCDOI | 10.18926/15334 |
|---|---|
| Title Alternative | Spa therapy for bronchial asthma. Spa therapies effective for bronchial asthma and problems in future. |
| FullText URL | 064_105_110.pdf |
| Author | Tanizaki, Yoshiro| |
| Abstract | 気管支喘息に対する温泉療法の作用,あるいは効果は,直接作用と間接作用,局所作用と全身作用,即時的効果と遠隔効果などに分類される｡気管支喘息に対する温泉療法の直接作用としては,呼吸器症状およびそれに関連した検査成績の改善として,また間接作用としては副腎皮質機能の改善作用がみられる｡一方,気管支喘息に有用な温泉療法としては,温泉プール水泳訓練,ヨードゾル吸入療法,および鉱泥湿布療法などが明らかにされており,現在これらの温泉療法を組み合わせた複合温泉療法が行われている｡気管支喘息はその臨床病態より,Ia-1.Ia-2,Ib,およびII型に分類される｡このうち,特にIb型やII型は薬物療法のみではコントロールし難い重症難治性喘息を多く含んでいる｡温泉療法は,気管支喘息全般に有効であるばかりでなく,特に薬物療法のみではコントロール困難なIb型やII型の喘息に対しても有効である。しかし,今後新たに気管支喘息に有用な温泉療法を考案して行かねばならない。 |
| Keywords | 温泉療法 (Spa therapy) 温泉プール水泳訓練 (Swimming training in a hot spring pool) ヨードゾル吸入 (Inhalation of iodine salt solution) 鉱泥湿布療法 (Fango therapy) 気管支喘息 (Bronchial asthma) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1993-06 |
| Volume | volume64 |
| Start Page | 105 |
| End Page | 110 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307660 |
| JaLCDOI | 10.18926/15333 |
|---|---|
| Title Alternative | Spa therapy for bronchial asthma. Inhalation therapy with hot spnng water and iodine salt solution |
| FullText URL | 064_111_115.pdf |
| Author | Tanizaki, Yoshiro| |
| Abstract | 慢性閉塞性呼吸器疾患,特に気管支喘息に対する温泉療法は.温泉療法そのものの効果以外に,温泉保養地の周囲環境が疾患に極めて良好であるという利点を有している｡温泉水やヨードゾルによる吸入療法は,気管支喘息に対して有効であるが,治療効果をより良好なものにするためには,各喘息症例の気道内病態を十分把握しておく必要がある｡板状貯留を呈する過分泌型喘息や細気管支閉塞型喘息に対しては,吸入療法の効果は一般的に低い｡代表的なヨー ドゾル吸入療法の臨床効果は,気管支喘息20例中,著効4例(20%),有効11例(55%),やや有効4例(20%),無効1例であった。 |
| Keywords | 温泉療法 (Spa therapy) 吸入療法 (Inhalation therapy) 温泉水 (Hot spring water) ヨードゾル (lodine salt solution) 気管支喘息 (Bronchial asthma) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1993-06 |
| Volume | volume64 |
| Start Page | 111 |
| End Page | 115 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307467 |
| JaLCDOI | 10.18926/15332 |
|---|---|
| Title Alternative | 気管支肺胞洗浄液中リンパ球増多と患者年齢およびIgE系アレルギー反応との関連について |
| FullText URL | 064_097_104.pdf |
| Author | Tanizaki, Yoshiro| Kitani, Hikaru| Mifune, Takashi| Mitsunobu, Fumihiro| Kimura, Ikuro| |
| Abstract | The proportion and number of lymphocytes in the airways were analyzed in 15 patients with a high proportion of lymphocytes in bronchoalveolar lavage (BAL) fluid (more than 30%) and in 17 patients with less than 20% of BAL lymphocytes. 1. Both atopic and nonatopic asthma patients with a high proportion of BAL lymphocytes were aged more than 50 years. In contrast, the age of patients with less than 20% of BAL lymphocytes ranged widely, from 29 to 63 years, in the two asthma types. 2. Age at onset of the disease, serum IgE levels, and ventilatory function test were not related to the proportion of BAL lymphocytes. 3. In patients with a high proportion of BAL lymphocytes, the mean proportion of these cells was 47.3% in atopic patients and 36.4% in non-atopic patients, i. e., there was no significant difference between the two asthma types. The absolute number of BAL lymphocytes in these patients was significantly higher in atopic (5.62×10(6)) than in nonatopic asthma (0.77×10(6)) (p<0.01). These findings show that an increased number of lymphocytes in the airways is clearly related to patient age and IgE-mediated allergic reaction. |
| Keywords | BAL lymphocytes patient age IgE-mediated allergic reaction bronchial asthma |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1993-06 |
| Volume | volume64 |
| Start Page | 97 |
| End Page | 104 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307637 |
| JaLCDOI | 10.18926/15331 |
|---|---|
| Title Alternative | ラット腹腔肥満細胞のCa(2+) influxおよびヒスタミン遊離に対する抗アレルギー薬アゼラスチンの抑制効果について |
| FullText URL | 063_089_094.pdf |
| Author | Tanizaki, Yoshiro| Ohtani, Jun| Kimura, Ikuro| |
| Abstract | The effect of antiallergic agent, azelastine, was examined in immunogical secretory process of mast cells. 1. Azelastine significantly inhibited (45)Ca uptake by mast cells stimulated by antigen, and the maximum inhibition was attained at a concentration of 50 μg/ml showing approximately 30.5 % inhibition. 2. Azelastine also inhibite the release of histamine from mast cells by antigen. The maximal inhibitory rate was 38.1%. The effect of azelastine on (45)Ca uptake and histamine release was dose-dependent, and compatible at employed cocentration of the agent. 3. Tachpylaxis to azelastine was not found in this experimental system. |
| Keywords | Azelastine (アゼラスチン) Rat mast cells (ラット肥満細胞) (45)Ca uptake (Ca(2+)uptake) Histamine release (ヒスタミン遊離) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 89 |
| End Page | 94 |
| ISSN | 0913-3771 |
| language | English |
| File Version | publisher |
| NAID | 120002307786 |
| JaLCDOI | 10.18926/15330 |
|---|---|
| Title Alternative | The efficacy of maternity swimming to reduce mother's weight |
| FullText URL | 063_085_088.pdf |
| Author | Okuda, Hiroyuki| Takatori, Akimasa| Sakata, Junko| Kamimoto, Manabu| Fujii, Junko| Dokai, Chiho| Tanizaki, Yoshiro| |
| Abstract | 第1報において妊婦水泳に関する妊婦の認識について報告し (1) ,第2報において妊婦水泳の現状とその適応について報告した (2) ｡その後,第3報において妊婦水泳が母児の循環系におぼす影響について報告し (3) ,第4報にて出産後1年間の児の予後調査を行った (4) 。今回は,妊婦水泳による体重減少効果について検討を行った。その結果,妊婦水泳前後で平均460gの体重減少がみられた｡また水泳を10回以上行った妊婦において,水泳を行っている期間の体重増加が水泳を行っていない期間の体重増加に比べて有意に少なかった｡これより,妊婦水泳には一定の減量効果があり,肥満妊婦の治療にも応用できると考えられた。 |
| Keywords | 妊婦水泳 (Maternity Swimming) 体重減少 (Reduce mother's weight) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 85 |
| End Page | 88 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307789 |
| JaLCDOI | 10.18926/15329 |
|---|---|
| Title Alternative | Character, Habit and Taste of woman with coldeness in their bodies |
| FullText URL | 063_079_084.pdf |
| Author | Takatori, Akimasa| Okuda, Hiroyuki| Sakata, Junko| Fujii, Junko| Tanizaki, Yoshiro| |
| Abstract | 冷え性の発現は寒冷刺激に対する血管運動性体温調節と密接に関係しているが,患者の性格･生活習慣･食事の嗜好等にも関わっていると考えられる｡そこで今回は冷え性婦人100名を対象にCMl調査と35項目にのぼるアンケート調査を行った｡その結果,冷え性の増悪因子として,日頃の運動不足･神経症的性格傾向･過労･食べ物の嗜好がクローズアップされ,この面での生活指導が冷え性の治療を行っていく上で,薬物的な治療と並んで重要であることか示唆された。 |
| Keywords | 冷え性 (Coldness in women) 性格 (Character) 生活習慣 (Habit) 嗜好 (Taste) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 79 |
| End Page | 84 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307750 |
| JaLCDOI | 10.18926/15328 |
|---|---|
| Title Alternative | Relationship between bone mineral densities of second metacarpal bone and lumber spine |
| FullText URL | 063_099_105.pdf |
| Author | Nakai, Mutsuo| Okuda, Hiroyuki| Akiyama, Tsuneo| Takatori, Akimasa| Tanizaki, Yoshiro| |
| Abstract | QCTおよびDIP法による測定値の相関性について検討し,DIP法による腰椎骨塩量の推定および,スクリーニングへの適用について考察した｡QCT値とΣGS/DやMClとの相関関係の検討では.対象のQCT値が低値か高値かによって相関関係がかなり異なることが明らかになった｡すなわち,QCT値が低い領域は,QCT値と,ΣGS/DやMCIに明らかな正の相関関係が認められたが,一方, QCT値が高い領域では,相関関係は認められなかった｡また,ΣGS/D=2.8mmAI以上,またはMCI=0.48以上の症例においては腰椎圧迫骨折の危険は小さく,ΣGS/D=1.8mmAI以下,またはMCI=0.24以下の症例においては腰椎圧迫骨折の危険が大きい可能性が示唆された。 |
| Keywords | 骨粗鬆症 (osteoporosis) 骨塩量 (bone mineral density) QCT (quantitative computed tomography) DIP法 (digital image processing method) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 99 |
| End Page | 105 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307484 |
| JaLCDOI | 10.18926/15327 |
|---|---|
| Title Alternative | Inhibitory effect of furosemide on histamine release from human basophils |
| FullText URL | 063_095_098.pdf |
| Author | Kitani, Hikaru| Kusaura, Yasuhiro| Honke, Naoko| Tanimizu, Masakuni| Mitsunobu, Fumihiro| Mifune, Takashi| Okazaki, Morihiro| Tanizaki, Yoshiro| |
| Abstract | furosemideは利尿剤として知られているが,吸入することにより気道収縮に対して抑制的に作用することが近年報告されている｡その抑制作用の機序を明らかにする目的で,furosemide添加による末梢血好塩基球からのヒスタミン遊離に対する抑制効果を検討した｡健常人4例,アトピー型気管支喘息患者8例を対象として全血法で抗ヒトIgE刺激によるヒスタミン遊離を観察した｡なお,furosemideの最終濃度は0,1,10,100μg/mlに調整して添加実験を行った｡健常人,気管支喘息いずれにおいても,furosemide添加による末梢血好塩基球からのヒスタミン遊離に対する抑制効果はみられなかった｡ |
| Keywords | 気管支喘息 (Bronchial asthma) フロセミド (Furosemide) ヒスタミン遊離 (Histamine release) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 95 |
| End Page | 98 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307119 |
| JaLCDOI | 10.18926/15326 |
|---|---|
| Title Alternative | Clinical evaluation of an endoscopic image filing system, Olympus SDF-3 |
| FullText URL | 063_074_078.pdf |
| Author | Ochi, Koji| Miyake, Hirofumi| Matsumoto, Shuji| Seno, Toshinobu| Tanaka, Juntaro| Harada, Hideo| Mitsunobu, Fumihiro| Tanizaki, Yosiro| |
| Abstract | 光ディスクとパーソナルコンピュータを組み合わせた内視鏡画像ファイリングシステムは電子内視鏡の画像の保存･管理,検索･再生などに威力を発揮する｡今回,われわれはオリンパス社製内視鏡ファイリングシステムSDF-3を使用する機会を得たので,その有用性や問題点の検討を行った｡有用性としては,①内視鏡画像を検査終了後直ちに再生し,再検討できる,②多数の項目についての検索や統計処理が可能である,③限られたスペース内で大量の画像データの一括保存･管理が可能であるなどが挙げられる｡一方,問題点としては,①内視鏡再生画像は画質が劣化する,②検索機能を十分に活用するにはかなり煩雑な人力操作を必要とする,③光ディスクの清掃が必要であるなどがあげられる｡本内視鏡ファイリングシステムに今後必要な改良点やその展望についても合わせて考案を加えた。 |
| Keywords | 画像ファイリングシステム (image filing system) 電子内視鏡 (electronic endoscope) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 74 |
| End Page | 78 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307278 |
| JaLCDOI | 10.18926/15325 |
|---|---|
| Title Alternative | 気管支喘息患者における細胞性免疫,ガンジダ抗原に対する遅延型反応の抑制 |
| FullText URL | 063_069_073.pdf |
| Author | Tanizaki, Yosiro| Kitani, Hikaru| Okazaki, Morihiro| Mifune, Takashi| Mitsunobu, Fumihiro| Harada, Hideo| Ochi, Koji| Kimura, Ikuro| |
| Abstract | Delayed cutaneous hypersensitivity towards Candida albicans was examined in 200 patients with bronchial asthma in relation to patient age and the level of total IgE. 1. Delayed skin reactivity towards C.albicans was depressed in the patients between the ages of 10 and 20 and in those over the age of 61. A significant difference was present in delayed skin reactivity between the groups of 10-20 and 41-50 years old. 2. The frequency of the patients with positive delayed skin reactivity towards C.albicans was the highest in those with low levels of total IgE (0 -100 IU/ml) and the low est in those with high levels of total IgE (over than 1001 IU/ml). The results suggest that cell-mediated immunity towards C.albicans is depressed re lating to atopics in the patients between 10 and 20 and to aging in the patients over 61. |
| Keywords | cell-mediated immunity (細胞性免疫) bronchial asthma (気管支喘息) atopics (アトピー) aging (加齢) カンジダ |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 69 |
| End Page | 73 |
| ISSN | 0913-3771 |
| language | English |
| File Version | publisher |
| NAID | 120002307949 |
| JaLCDOI | 10.18926/15324 |
|---|---|
| Title Alternative | 臨床所見および検査成績からのスコアーによる喘息分類の特徴 |
| FullText URL | 063_063_068.pdf |
| Author | Tanizaki, Yoshiro| Kitani, Hikaru| Okazaki, Morihiro| Mifune, Takashi| Mitsunobu, Fumihiro| Tanimizu, Masakuni| Honke, Naoko| Kusaura, Yasuhiro| Takatori, Akimasa| Okuda, Hiroyuki| Kimura, Ikuro| |
| Abstract | Twenty six patients with bronchial asthma was classified by clinical symptoms and singns (clinical diagnosis), and the classification by clinical diagnosis was compared with the classification by a score calculated from clinical findings and examinations (score diagnosis). 1. Of 12 subjects with type Ia classified by clinical diagnosis, 8 cases with 0 to 49 ml/day of expectoration were evaluated as type Ia by score diagnosis. While four type Ia cases with 50 to 99ml/day of expectoration were calssified as type Ib by score diagnosis. The increased incidence of eosinophils in bronchoalveolar lavage fluid (BALF) of these four cases was similar to the incidence in type Ib cases with hypersecretion. 2. All of 6 subjects with type Ib by clinical diagnosis were estimated as type Ib by score diagnosis. 3. Of 8 cases with type II by clinical diagnosis, 7 cases were assessed as type II by score diagnosis. One case with type II by clinical diagnosis and with the score of 10 points was evaluated as questionable type II by score diagnosis. |
| Keywords | asthma classification (喘息分類) bronchoconstriction (気管支攣縮) hypersecretion (過分泌) bronchiolar obstruction (細気管支閉塞) score diagnosis (スコアー診断) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 63 |
| End Page | 68 |
| ISSN | 0913-3771 |
| language | English |
| File Version | publisher |
| NAID | 120002307348 |
| JaLCDOI | 10.18926/15322 |
|---|---|
| Title Alternative | 高齢者健常人および気管支喘息患者におけるカンジダ特異的IgGおよびIgG(4)抗体について |
| FullText URL | 063_058_062.pdf |
| Author | Tanizaki, Yoshiro| Kitani, Hikaru| Okazaki, Morihiro| Mifune, Takashi| Mitsunobu, Fumihiro| Kotoh, Naoki| Tada, Shinya| Kimura, Ikuro| |
| Abstract | Specific IgG and IgG(4) antibodies against Canadida albicans were exmined in 48 healthy and 69 asthmatic subjects to analyze the mechanism causing an increased production of these immunoglobulins. 1. The level of C.albicans-specific IgG and IgG(4) antibodies was higher, not significantly in IgG(4), in asthmatics under 30 years of age, compared with healthy subjects of the same age group. 2. Specific IgG and IgG(4) antibody levels in both healthy and asthmatic subjects showed a tendency to increase with aging, and significant difference was present between cases under 30 years and cases over 70 years of age. 3. Any difference in the production of specific IgG and IgG(4) was not observed in elderly cases older than 60 years between healthy and asthmatic subjects. |
| Keywords | Candida albicans (カンジダ特異的IgG) Specific IgG IgG(4) Bronchial asthma (気管支喘息) Aging (加齢) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 58 |
| End Page | 62 |
| ISSN | 0913-3771 |
| language | English |
| File Version | publisher |
| NAID | 120002307284 |
| JaLCDOI | 10.18926/15321 |
|---|---|
| Title Alternative | IgE受容体を介する刺激に対する好塩基球の形態的変化の顕微鏡的観察. 抗原と抗IgE刺激の特徴とその相違点 |
| FullText URL | 063_050_057.pdf |
| Author | Tanizaki, Yoshiro| Nakagawa, Saburo| Kimura, Ikuro| |
| Abstract | Differences in morphological changes of basophils between antigen and anti-IgE stimulation were examined in atopic subjects in relation to histamine release. 1. Antigen- induced release of histamine was remarkably more rapid and larger at any incubation time than the release by anit-IgE, and a significant difference was found at 3 to 9 min. 2. Decrease in number of basophils induced by antigen was significantly higher for 12 to 15 min incubation time than that by anti-IgE. 3. Morphological changes of basophils representing increased motility such as an increased ratio of short to long axis diameter (L/S ratio) and an increased incidence of basophils with localized granules (LG) were more often observed in antigen stimulation compared with anti-IgE, and the L/S ratio of the cells was significantly more increased in antigen stimulation at 6 and 15 min. 4. There was no difference in morphological changes of basophils showimg swollen type (degranulation) such as an increased mean diameter (MD) of the cells between antigen and anti-IgE. These results suggest that antigen activates basophils and induces increased motility more strongly than anti-IgE, but the action on degranulation was not different between the two agents. |
| Keywords | Histamine release (ヒスタミン遊離) Morphological changes of basophils (好塩基球の形態的変化) Antigen (抗原) Anti-IgE (抗IgE) IgE receptors (IgE受容体) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 50 |
| End Page | 57 |
| ISSN | 0913-3771 |
| language | English |
| File Version | publisher |
| NAID | 120002307320 |
| JaLCDOI | 10.18926/15320 |
|---|---|
| Title Alternative | 気管支喘息における気道の反応性および炎症反応におよぼす加齢の影響について |
| FullText URL | 064_089_096.pdf |
| Author | Tanizaki, Yoshiro| Kitani, Hikaru| Mifune, Takashi| Mitsunobu, Fumihiro| Kajimoto, Kazuhiro| Sugimoto, Keisuke| Harada, Hideo| Kimura, Ikuro| |
| Abstract | Ventilatory function, cellular composition in bronchoalveolar lavage (BAL) fluid and release of chemical mediators from leucocytes were examined in 25 older asthmatics (mean age 66.7 years) and 25 younger asthmatics (mean age 45.1 years) in relation to clinical asthma types. 1. Ventilatory function tests showed that the values of ventilatory parameters such as % MMF, % V(50) and % V(25) were lower in older subjects than in younger subjects, and a significant difference was found in the % V(50) value between the two age groups. Regarding clinical asthma types, the values of % MMF, % V(50), and V(25) were significantly lower in both younger and older subjects with type II. 2. In analysis of cellular composition in BAL fluid, the proportion of BAL lymphocytes was significantly lower in type II older subjects than in younger subjects with the same type. A significantly increased proportion of BAL neutrophils was observed in both younger and older subjects with type II. 3. The release of leukotriene C(4) (LTC(4)) from leucocytes was significantly lower in type II older subjects than in younger subjects with the same type, and LTC(4) release in patients with type II was also significantly lower than that in those with other asthma types in both younger and older subjects. The release of histamine and leukotriene B(4) (LTB(4)) from leucocytes was not significantly different between the two age groups. These results demonstrate that ventilatory function, cellular composition in BAL fluid, and the release of chemical mediators from leucocytes are affected by aging and clinical asthma types. |
| Keywords | Ventilatory function (換気機能) Cellular composition in BAL fluid (気道内細胞成分) chemical mediators (化学伝達物質) aging (加齢) clinical asthma type (臨床病型) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1993-06 |
| Volume | volume64 |
| Start Page | 89 |
| End Page | 96 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307744 |
| JaLCDOI | 10.18926/15319 |
|---|---|
| Title Alternative | Effects of vitamin D and exercise on bone mineral density (BMD) measuured by QCT |
| FullText URL | 064_071_074.pdf |
| Author | Hiramatsu, Junnichi| Kawaraya, Masashi| Yokota, Satoshi| Sugimoto, Keisuke| Mitsunobu, Fumihiro| Mifune, Takashi| Kajimoto, Kazuhiro| Kitani, Hikaru| Tanizaki, Yoshiro| Nakai, Mutsuro| Akiyama, Tsuneo| |
| Abstract | 40才～84才(平均64.1才)の患者38例における骨塩量を,ある期間(1～15カ月,平均8.2カ月)をおいて2回,定量的QCT(quantitative computed tomography)法を用いて測定し,その経時的変化によって,骨粗鬆症に対する治療法の効果判定を試みた｡その結果,(1)全体として骨塩量に有意の増加は認められなかった｡(2)骨強化剤使用例についても骨塩量に有意の増加は認められなかった｡(3)運動療法施行者においても骨塩量に有意の増加は認められなかった｡以上のことから骨粗鬆症の治療においては,約1年弱の経過では著明な反応は得られにくいものと思われた｡ただし,一部の運動療法施行者,骨強化剤使用者において,骨塩量の著明な上昇が認められており,さらに経時的な観察が必要と思われた。 |
| Keywords | 骨粗鬆症 (Osteoprosis) 定量的QCT法 (QCT) 加齢 (Aging) 運動療法 (Exercise) ビタミンD (Vitamin D) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1993-06 |
| Volume | volume64 |
| Start Page | 71 |
| End Page | 74 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307358 |
| JaLCDOI | 10.18926/15318 |
|---|---|
| Title Alternative | 老令者の気管支喘息,各臨床病型における換気機能の特徴 |
| FullText URL | 063_044_049.pdf |
| Author | Tanizaki, Yoshiro| Kitani, Hikaru| Okazaki, Morihiro| Mifune, Takashi| Mitsunobu, Fumihiro| Tanimizu, Masakuni| Honke, Naoko| Kusaura, Yasuhiro| Takatori, Akimasa| Okuda, Hiroyuki| Kimura, Ikuro| |
| Abstract | Ventilatory function was examined in 20 elderly patients with bronchial asthma in relation to clinical asthma types, and the results were compared with those of younger asthmatics. 1. Ventilatory parameters such as FEV(1.0%), % PEFR, % MMF, % V(50) and % V(25), which repressent obstructive ventilatory dysfunction, were in general lower in older asthmatics than in the youger cases. 2. The values of % V(50) and % V(25), representing ventilatory dysfunction in small airways, were significantly lower in the older subjects with type Ib and II compared to the younger cases with same types. 3. Markedly decreased values in ventilatory parameters, particularly in % MMF, % V(50) and % V(25) were observed in both older and younger subjects with type II. The results suggest that ventilatory function decreases with aging and the decrease is related to the pathophysiological changes in the airways. |
| Keywords | Ventilatory function (換気機能) small airways (細気管支) clinical asthma types (臨床病型) elderly asthmatics (老年者気管支喘息) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 44 |
| End Page | 49 |
| ISSN | 0913-3771 |
| language | English |
| File Version | publisher |
| NAID | 120002307531 |
| JaLCDOI | 10.18926/15317 |
|---|---|
| Title Alternative | Diagonosis of pancreatic cyst using post-ERCP CT examination. |
| FullText URL | 064_065_070.pdf |
| Author | Ochi, Koji| Harada, Hideo| Matsumoto, Shuji| Seno, Tosinobu| Tanaka, Juntaro| Riaz Chowdhury| Mizushima, Takaaki| Sugimoto, Keisuke| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| Nakai, Mutsuo| Akiyama, Tsuneo| Hasuoka, Hideaki| |
| Abstract | ERCP直後にCTを撮影するERCP後CTはERCPの際に膵内に注入された造影剤をCTで検出するため,ERCPでは得られない情報が得られる利点がある｡われわれはERCP後CTが診断や治療方針の決定に有用であった膵嚢胞の4例を経験した｡膵嚢胞では主膵管との連絡,嚢胞の部位,性状診断にERCP後CTは有用な検査法であり,文献的考察を含めて報告した｡ |
| Keywords | ERCP (Endoscopic retrograde cholangiopancreatography) CT (Computed tomography) 膵嚢胞 (pancreatic cyst) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1993-06 |
| Volume | volume64 |
| Start Page | 65 |
| End Page | 70 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307547 |
| JaLCDOI | 10.18926/15316 |
|---|---|
| Title Alternative | 老年者の気管支喘息. アレルギー反応と気道細胞反応 |
| FullText URL | 063_039_043.pdf |
| Author | Tanizaki, Yoshiro| Kitani, Hikaru| Okazaki, Morihiro| Mifune, Takashi| Mitsunobu, Fumihiro| Tanimizu, Masakuni| Honke, Naoko| Kusaura, Yasuhiro| Ochi, Koji| Harada, Hideo| Kimura, Ikuro| |
| Abstract | Clinical features of bronchial asthma in the elderly were analyzed by observlng IgE-mediated allerglc reactions evaluated by immediate skin reaction and specific IgE antibodies to allergens, ventilatory function and cellular composition in bronchoalveolar lavage (BAL) fluid. 1. The frequency of positive immediate skin reaction and positive RAST score to allergens was in general low in the elderly patients over age 70. 2. Ventilatory function was widely variegated, and fifteen cases (60%) of the 25 Subjects showed considerably high values of FEV(l.0%), % PEFR, % MMF, % V(50) and % V(25), and the mean value of FEV(1.0%) in these cases was 71.3%. 3. The decreased value of % V(25) was related to BAL neutrophilia in 2 cases, but any correlation was not found between BAL neutrophilia and decreased value of % V(25) in 9 csese of the eleven subjects who had the BAL examination. The results show that in asthma of elderly patients, IgE-mediated allergic reactions are weak, and that a decreased value of % V(25) can be observed without BAL neutrophilia. |
| Keywords | elderly subjects (老年者) lgE-mediated allergic reaction (IgE系反応) ventilatory function (換気機能) BAL neutrophilia (BAL好中球) bronchial asthma (気管支喘息) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1992-06 |
| Volume | volume63 |
| Start Page | 39 |
| End Page | 43 |
| ISSN | 0913-3771 |
| language | English |
| File Version | publisher |
| NAID | 120002307727 |
| JaLCDOI | 10.18926/15315 |
|---|---|
| Title Alternative | Effects of the spring water on the dissolution of aminophylline tablet and theophylline sustained-release preparations |
| FullText URL | 064_060_064.pdf |
| Author | Mimaki, Yuichi| Fujii, Yoshihiro| Furuno, Katsushi| Gomita, Yutaka| Araki, Yasunori| Tanizaki, Yoshiro| |
| Abstract | 薬物のbioavailabilityに影響する因子の一つとして,製剤からの薬物の溶出速度が考えられる｡今回,温泉水による薬物溶出への影響を知る目的で,気管支喘息治療薬のアミノフィリン製剤およびテオフィリン徐放製剤の溶出挙動について検討した｡溶出試験は第12改正日本薬局方に従い,第1法(回転バスケット法)および第2法(パドル法)で行い,試験液を蒸留水および三朝温泉水として両者の溶出挙動を比較した｡アミノフィリン製剤では,10分後まで 温泉水の方が有意に高い溶出率を示した｡また,テオフィリン徐放製剤においても温泉水が8時間後まで蒸留水に比べて有意に高い溶出率を示した｡以上の結果より,アミノフィリン製剤およびテオフィリン徐放製剤は温泉水により薬物の溶出が促進されることか示唆された。 |
| Keywords | 溶出試験 (Dissolutionte test) 温泉水 (Spring water) 気管支喘息治療薬 (Bronchial asthma therapeutic drug) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1993-06 |
| Volume | volume64 |
| Start Page | 60 |
| End Page | 64. |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307434 |
