JaLCDOI | 10.18926/AMO/53679 |
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FullText URL | 69_5_319.pdf |
Author | Hagiya, Hideharu| Iwamuro, Masaya| Tanaka, Takehiro| Hanayama, Yoshihisa| Otsuka, Fumio| |
Abstract | A 60-year-old woman with rheumatoid arthritis treated with methotrexate for a decade complained of slight epigastric discomfort. A positive cytomegalovirus (CMV) antigenemia test indicated the probability of CMV-related gastrointestinal infection, for which esophagogastroduodenoscopy was performed. Endoscopic findings showed a non-specific duodenal mucosal lesion;however, pathological investigation revealed evidence of CMV duodenitis. There is scarce information on the clinical and pathological features of CMV-related duodenitis, likely due to its low prevalence. CMV infection in the upper gastrointestinal tract should be considered as a differential diagnosis in high-risk individuals, particularly those with symptoms relating to the digestive system. Biopsy examinations are preferable for the definitive diagnosis of CMV gastrointestinal infection, even without specific endoscopic features. |
Keywords | antigenemia cytomegalovirus (CMV) gastrointestinal infection methotrexate opportunistic infection |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2015-10 |
Volume | volume69 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 319 |
End Page | 323 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 26490030 |
Web of Science KeyUT | 000365519600009 |
JaLCDOI | 10.18926/AMO/53120 |
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FullText URL | 69_1_37.pdf |
Author | Iwamuro, Masaya| Okada, Hiroyuki| Takata, Katsuyoshi| Kawai, Yoshinari| Kawano, Seiji| Nasu, Junichiro| Kawahara, Yoshiro| Tanaka, Takehiro| Yoshino, Tadashi| Yamamoto, Kazuhide| |
Abstract | The sensitivity and specificity of magnified endoscopic features for differentiating follicular lymphoma from other diseases with duodenal whitish lesions have never been investigated. Here we compared the magnified endoscopic features of duodenal follicular lymphoma with those of other whitish lesions. We retrospectively reviewed the cases of patients with follicular lymphoma (n=9), lymphangiectasia (n=7), adenoma (n=10), duodenitis (n=4), erosion (n=1), lymphangioma (n=1), and hyperplastic polyp (n=1). The magnified features of the nine follicular lymphomas included enlarged villi (n=8), dilated microvessels (n=5), and opaque white spots of various sizes (n=9). The lymphangiectasias showed enlarged villi, dilated microvessels, and white spots, but the sizes of the white spots were relatively homogeneous and their margin was clear. Observation of the adenoma and duodenitis revealed only whitish villi. Although the lymphangioma was indistinguishable from the follicular lymphomas by magnified features, it was easily diagnosed based on the macroscopic morphology. In conclusion, magnified endoscopic features, in combination with macroscopic features, are useful for differentiating follicular lymphomas from other duodenal diseases presenting whitish lesions. |
Keywords | duodenal neoplasm follicular lymphoma gastrointestinal lymphoma magnifying endoscopy |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2015-02 |
Volume | volume69 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 37 |
End Page | 44 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 25703169 |
Web of Science KeyUT | 000349740300004 |
JaLCDOI | 10.18926/AMO/52900 |
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FullText URL | 68_5_307.pdf |
Author | Muro, Shinichiro| Nasu, Junichiro| Harada, Ryo| Matsubara, Minoru| Nakarai, Asuka| Kanzaki, Hiromitsu| Tsutsumi, Kouichiro| Kato, Hironari| Tanaka, Takehiro| Fujiwara, Hiroyasu| Uno, Masatoshi| Okada, Hiroyuki| Yamamoto, Kazuhide| |
Abstract | A 45-year-old female who presented with loss of consciousness and a cold sweat was found to have a pancreatic tumor and multiple liver metastases. Laboratory studies showed marked hypoglycemia and inappropriately elevated serum insulin, C-peptide, and serum tumor markers. Fine needle aspiration revealed Grade 3 small-cell type primary pancreatic neuroendocrine carcinoma. Consequently, the diagnosis of malignant insulinoma was made. Transarterial embolization (TAE) for hepatic metastases resulted in the reduction of tumor volume and prompt resolution of hypoglycemic attacks, whereas diazoxide and systemic chemotherapy had been ineffective for controlling blood glucose levels, and octreotide was unavailable due to the allergic effect. This case report highlights the potential usefulness of TAE for malignant insulinomas in the management of hypoglycemia. |
Keywords | malignant insulinoma hypoglycemia liver metastases transarterial embolization neuroendocrinetumor |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2014-10 |
Volume | volume68 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 307 |
End Page | 311 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 25338488 |
Web of Science KeyUT | 000343269300008 |
Author | Sugiyama, Haruko| Maeda, Yoshinobu| Nishimori, Hisakazu| Yamasuji, Yoshiko| Matsuoka, Ken-ichi| Fujii, Nobuharu| Kondo, Eisei| Shinagawa, Katsuji| Tanaka, Takehiro| Takeuchi, Kengo| Teshima, Takanori| Tanimoto, Mitsune| |
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Published Date | 2014-02 |
Publication Title | Biology of Blood and Marrow Transplantation |
Volume | volume20 |
Issue | issue2 |
Content Type | Journal Article |
JaLCDOI | 10.18926/AMO/52659 |
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FullText URL | 68_3_177.pdf |
Author | Mizuno, Shoma| Ota, Seisuke| Tanaka, Takehiro| Shiomi, Kohei| Matsumura, Tadashi| Kishimoto, Nobuyasu| |
Abstract | Primary tracheal malignant lymphoma is a rare disease;only 30 cases have been reported to date. A 73-year-old Japanese man with a history of asbestos exposure was undergoing biannual chest computed tomography (CT) twice a year as a routine procedure for those previously exposed to asbestos. He had been smoking since the age of 32. In September 2010, chest CT during this regular checkup revealed a polypoid lesion in his trachea and pleural plaques, which were suspected to be caused by asbestos. Bronchoscopy performed in October revealed a polypoid lesion with granules and nodules in the trachea. A diagnosis of non-Hodgkin lymphoma (NHL) and extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) was confirmed by histological analysis of the biopsy specimens. To our knowledge, this is the first case of primary tracheal lymphoma associated with a history of asbestos exposure. Several reports have documented no correlation between asbestos and malignant lymphoma. In addition, the correlation between smoking and NHL is weak. Although we cannot exclude the possibility of a simple coincidence of asbestos, smoking, and tracheal lymphoma, this case suggests that asbestos and smoking might have multiplicative effects in the development or progression of tracheal lymphoma. |
Keywords | bronchus-associated lymphoid tissue tracheal lymphoma regular checkup asbestos smoking |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2014-06 |
Volume | volume68 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 177 |
End Page | 181 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 24942797 |
Web of Science KeyUT | 000337655600008 |
FullText URL | WorldJHepatology_5_4_189-195.pdf |
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Author | Satoh, Daisuke| Yagi, Takahito| Nagasaka, Takeshi| Shinoura, Susumu| Umeda, Yuzo| Yoshida, Ryuichi| Utsumi, Masashi| Tanaka, Takehiro| Sadamori, Hiroshi| Fujiwara, Toshiyoshi| |
Keywords | Non-alcoholic fatty liver disease Pancreatoduodenectomy CD14 Endotoxin Kupffer cells |
Published Date | 2013-04-27 |
Publication Title | World Journal of Hepatology |
Volume | volume5 |
Issue | issue4 |
Start Page | 189 |
End Page | 195 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | ©2013 Baishideng Publishing Group Co., Limited. All rights reserved. |
File Version | publisher |
DOI | 10.4254/wjh.v5.i4.189 |
Official Url | http://www.wjgnet.com/1948-5182/full/v5/i4/189.htm| |
Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/51448 |
Author | Nogami, Tomohiro| Shien, Tadahiko| Tanaka, Takehiro| Nishiyama, Keiko| Mizoo, Taeko| Iwamto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Doihara, Hiroyoshi| Miyoshi, Shinichiro| |
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Published Date | 2012-03-10 |
Publication Title | Breast Cancer |
Content Type | Journal Article |