FullText URL fulltext.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro|
Keywords conjunctival lymphoma extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) follicular lymphoma diffuse large B-cell lymphoma fluorodeoxyglucose positron emission tomography (FDG-PET)
Published Date 2024
Publication Title Journal of Clinical and Experimental Hematopathology
Volume volume64
Issue issue2
Publisher Japanese Society for Lymphoreticular Tissue Research
Start Page 86
End Page 96
ISSN 1346-4280
NCID AA11556796
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Japanese Society for Lymphoreticular Tissue Research
File Version publisher
PubMed ID 38684405
DOI 10.3960/jslrt.24002
Web of Science KeyUT 001218537700001
Related Url isVersionOf https://doi.org/10.3960/jslrt.24002
FullText URL fulltext20240513-03.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro| Kimata, Yoshihiro|
Keywords hemangioma lymphangioma lymphatic malformation pathology trabeculectomy vascular malformation
Published Date 2024-05
Publication Title Clinical Case Reports
Volume volume12
Issue issue5
Publisher Wiley
Start Page e8933
ISSN 2050-0904
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Authors.
File Version publisher
PubMed ID 38741673
DOI 10.1002/ccr3.8933
Web of Science KeyUT 001218609400001
Related Url isVersionOf https://doi.org/10.1002/ccr3.8933
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-Ichi| Tanaka, Takehiro| Inokuchi, Toshihiro| Hiraoka, Sakiko| Otsuka, Motoyuki|
Keywords Colonoscopy Esophagogastroduodenoscopy Graft-versus-host disease Hematopoietic stem cell transplantation Intestinal transplant-associated microangiopathy iTAM
Note The version of record of this article, first published in BMC Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12876-024-03221-y|
Published Date 2024-04-22
Publication Title BMC Gastroenterology
Volume volume24
Issue issue1
Publisher BMC
Start Page 140
ISSN 1471-230X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38649868
DOI 10.1186/s12876-024-03221-y
Web of Science KeyUT 001206319800003
Related Url isVersionOf https://doi.org/10.1186/s12876-024-03221-y
JaLCDOI 10.18926/AMO/66915
FullText URL 78_2_123.pdf
Author Saeki, Kyosuke| Fujiwara, Hideaki| Seike, Keisuke| Kuroi, Taiga| Nishimori, Hisakazu| Tanaka, Takehiro| Matsuoka, Ken-ichi| Fujii, Nobuharu| Maeda, Yoshinobu|
Abstract Chronic graft-versus-host disease (GVHD) is a major cause of late death and morbidity following allogeneic hematopoietic cell transplantation (HCT), but its pathogenesis remains unclear. Recently, haplo-identical HCT with post-transplant cyclophosphamide (Haplo-HCT with PTCY) was found to achieve a low incidence rate of acute GVHD and chronic GVHD. However, while the pathogenesis of acute GVHD following Haplo-HCT with PTCY has been well investigated, that of chronic GVHD remains to be elucidated, especially in HLA-matched HCT with PTCY. Based on its safety profile, PTCY is currently applied for the human leucocyte antigen (HLA)-matched HCT setting. Here, we investigated the mechanisms of chronic GVHD following HLA-matched HCT with PTCY using a well-defined mouse chronic GVHD model. PTCY attenuated clinical and pathological chronic GVHD by suppressing effector T-cells and preserving regulatory T-cells compared with a control group. Additionally, we demonstrated that cyclosporine A (CsA) did not show any additional positive effects on attenuation of GVHD in PTCY-treated recipients. These results suggest that monotherapy with PTCY without CsA could be a promising strategy for the prevention of chronic GVHD following HLA-matched HCT.
Keywords GVHD posttransplant cyclophosphamide hematopoietic cell transplantation HLA-identical
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 123
End Page 134
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688830
Web of Science KeyUT 001229151800004
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Takenaka, Ryuta| Miyahara, Koji| Okanoue, Shotaro| Yoshioka, Masao| Sakaguchi, Chihiro| Yamamoto, Kumiko| Kawai, Yoshinari| Toyokawa, Tatsuya| Tanaka, Takehiro| Otsuka, Motoyuki|
Keywords Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue Gastric neoplasms Esophagogastroduodenoscopy t(11;18) translocation, Trisomy 18
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-55663-9|
Published Date 2024-02-29
Publication Title Scientific Reports
Volume volume14
Issue issue1
Publisher Nature Portfolio
Start Page 4953
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38418651
DOI 10.1038/s41598-024-55663-9
Web of Science KeyUT 001178149200009
Related Url isVersionOf https://doi.org/10.1038/s41598-024-55663-9
JaLCDOI 10.18926/AMO/66668
FullText URL 78_1_029.pdf
Author Kitayama, Takahiro| Tanaka, Takashi| Kanie, Yuichiro| Marukawa, Yohei| Kojima, Katsuhide| Tanaka, Takehiro| Takao, Soshi| Hiraki, Takao|
Abstract This retrospective study investigated whether necrotic lesions detected on a computed tomography (CT) scan are more regressive than non-necrotic lesions after methotrexate withdrawal in patients pathologically diagnosed with methotrexate-associated lymphoproliferative disorders (MTX-LPD). In total, 89 lesions extracted from 24 patients on CT scans were included in the analysis. All patients had been evaluated for the presence of necrosis within lesions via CT scan upon first suspicion of MTX-LPD (baseline CT scan). The percentage lesion size reduction between the baseline and initial follow-up CT scan was calculated. The association between necrosis within lesions and size changes was estimated via linear regression analyses using both crude and adjusted models. Necrosis was significantly more common in extranodal lesions (27 out of 30 lesions, 90%) than in nodal lesions (9 out of 59 lesions, 15%, p<0.001). In the crude model, the regression of necrotic lesions was 58.5% greater than that of non-necrotic lesions; the difference was statistically significant (p<0.001). Additionally, the longest diameter of necrotic lesions at the baseline CT scan was significantly greater than that of non-necrotic lesions (p<0.001). Based on the adjusted model, necrotic lesions showed 49.3% greater regression than non-necrotic lesions (p=0.017). Necrosis detected on a CT scan was found to be an independent predictor of regression after MTX withdrawal in patients with MTX-LPD.
Keywords methotrexate lymphoproliferative disorder computed tomography necrosis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-02
Volume volume78
Issue issue1
Publisher Okayama University Medical School
Start Page 29
End Page 36
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38419312
Web of Science KeyUT 001203658200001
FullText URL fulltext20231223-01.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro| Yamada, Kiyoshi| Nose, Motoko| Tanimoto, Yasushi|
Keywords debridement eyelid lacrimal sac Mycobacterium abscessus nontuberculous mycobacteria
Published Date 2023-12-21
Publication Title Clinical Case Reports
Volume volume11
Issue issue12
Publisher Wiley
Start Page e8364
ISSN 2050-0904
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 38130855
DOI 10.1002/ccr3.8364
Web of Science KeyUT 001128230600001
Related Url isVersionOf https://doi.org/10.1002/ccr3.8364
FullText URL fulltext.pdf
Author Toyosawa, Junki| Yamasaki, Yasushi| Fujimoto, Tsuyoshi| Tanaka, Shouichi| Tanaka, Takehiro| Mitsuhashi, Toshiharu| Okada, Hiroyuki|
Published Date 2022-05-13
Publication Title Endoscopy International Open
Volume volume10
Issue issue05
Publisher Georg Thieme Verlag KG
Start Page E602
End Page E608
ISSN 2364-3722
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022. The Author(s).
File Version publisher
PubMed ID 35571476
DOI 10.1055/a-1785-8616
Web of Science KeyUT 000794976400009
Related Url isVersionOf https://doi.org/10.1055/a-1785-8616
FullText URL fulltext.pdf
Author Otani, Yusuke| Yoshikawa, Soichiro| Nagao, Kei| Tanaka, Takehiro| Toyooka, Shinichi| Fujimura, Atsushi|
Keywords Mast cells Connective tissue mast cells Noradrenaline Immunoelectron microscopy SLC22A3
Note The version of record of this article, first published in The Journal of Physiological Sciences, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12576-023-00883-3|
Published Date 2023-10-12
Publication Title The Journal of Physiological Sciences
Volume volume73
Issue issue1
Publisher BMC
Start Page 24
ISSN 1880-6546
NCID AA12129145
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37828465
DOI 10.1186/s12576-023-00883-3
Web of Science KeyUT 001089236900002
Related Url isVersionOf https://doi.org/10.1186/s12576-023-00883-3
JaLCDOI 10.18926/AMO/65978
FullText URL 77_5_545.pdf
Author Iwamuro, Masaya| Tanaka, Shouichi| Toyokawa, Tatsuya| Nishimura, Mamoru| Tsuzuki, Takao| Miyahara, Koji| Negishi, Shin| Ohya, Shogen| Tanaka, Takehiro| Otsuka, Motoyuki|
Abstract To determine the endoscopic and clinical features of localized gastric amyloid light-chain (AL) amyloidosis, we retrospectively examined the characteristics of nine patients (eight men and one woman) encountered by the hospitals in our network. Lesions were predominantly flat and depressed with surface vascular dilatation (n=5); others were characterized by subepithelial lesions (n=2), mucosal color change (n=1), and a mass-like morphology with swollen mucosal folds (n=1). Colonoscopy (n=7), video capsule enteroscopy (n=2), serum (n=5) and urine immunoelectrophoresis (n=4), and bone marrow examination (n=3) were performed to exclude involvement of organs other than the stomach. As treatment for gastric lesions of AL amyloidosis, one patient each underwent endoscopic submucosal dissection (n=1) and argon plasma coagulation (n=1), while the remaining seven patients underwent no specific treatment. During a mean follow-up of 4.2 years, one patient died 3.2 years after diagnosis, but the cause of death, which occurred in another hospital, was unknown. The remaining eight patients were alive at the last visit. In conclusion, although localized gastric AL amyloidosis can show various macroscopic features on esophagogastroduodenoscopy, flat, depressed lesions with vascular dilatation on the surface are predominant.
Keywords esophagogastroduodenoscopy gastric lesion amyloidosis light chain
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 545
End Page 552
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899266
Web of Science KeyUT 001094245100001
FullText URL fulltext20230923-01.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro|
Keywords myxoma orbital CD34 ethmoid sinus literature review
Published Date 2023-09-22
Publication Title Journal of Investigative Medicine High Impact Case Reports
Volume volume11
Publisher SAGE Publications
Start Page 1
End Page 6
ISSN 2324-7096
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 American Federation for Medical Research
File Version publisher
PubMed ID 37737575
DOI 10.1177/23247096231201013
Web of Science KeyUT 001070220300001
Related Url isVersionOf https://doi.org/10.1177/23247096231201013
FullText URL fulltext.pdf
Author Yamamoto, Shumpei| Kinugasa, Hideaki| Yamasaki, Yasushi| Hirai, Mami| Ako, Soichiro| Takei, Kensuke| Igawa, Shoko| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Inokuchi, Toshihiro| Harada, Keita| Hiraoka, Sakiko| Nouso, Kazuhiro| Tanaka, Takehiro| Okada, Hiroyuki|
Keywords colorectal ESD PECS electrocoagulation syndrome immunosuppressants and steroids post-ESD fever
Published Date 2021-12-09
Publication Title DEN Open
Volume volume2
Issue issue1
Publisher Wiley
Start Page e83
ISSN 2692-4609
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Authors.
File Version publisher
PubMed ID 35310725
DOI 10.1002/deo2.83
Web of Science KeyUT 001047024900091
Related Url isVersionOf https://doi.org/10.1002/deo2.83
FullText URL fulltext.pdf
Author Kanzaki, Hiromitsu| Horii, Joichiro| Takenaka, Ryuta| Nakagawa, Hiroyuki| Matsueda, Kazuhiro| Tsuzuki, Takao| Kita, Masahide| Yamasaki, Yasushi| Tanaka, Takehiro| Iwamuro, Masaya| Kawano, Seiji| Kawahara, Yoshiro| Tomoda, Jun| Okada, Hiroyuki|
Published Date 2022-06-10
Publication Title Endoscopy International Open
Volume volume10
Issue issue06
Publisher Georg Thieme Verlag KG
Start Page E712
End Page E718
ISSN 2364-3722
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022. The Author(s).
File Version publisher
PubMed ID 35859656
DOI 10.1055/a-1793-9439
Web of Science KeyUT 000826506700001
Related Url isVersionOf https://doi.org/10.1055/a-1793-9439
FullText URL fulltext.pdf
Author Chen, Mengxi| Tanaka, Takehiro| Igawa, Takuro| Han, Yanyan| Peng, Fangli| Jin, Zaishun| Yoshino, Tadashi|
Keywords PDX1 PTF1A SALL4 Ectopic pancreas Gastro-duodenum Jejunum
Published Date 2023-07
Publication Title Heliyon
Volume volume9
Issue issue7
Publisher Cell Press
Start Page e18241
ISSN 2405-8440
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 37519669
DOI 10.1016/j.heliyon.2023.e18241
Web of Science KeyUT 001043928200001
Related Url isVersionOf https://doi.org/10.1016/j.heliyon.2023.e18241
JaLCDOI 10.18926/AMO/65740
FullText URL 77_4_347.pdf
Author Iwamuro, Masaya| Kondo, Takumi| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-ichi| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Maeda, Yoshinobu| Okada, Hiroyuki|
Abstract The feasibility of lymphocyte isolation and flow cytometry using a single endoscopic biopsy specimen from the gastrointestinal tract of patients who have undergone hematopoietic stem cell transplantation has not been investigated. We acquired 51 endoscopic biopsy specimens from the gastrointestinal tract of 35 patients. We divided the flow cytometry samples into two groups: group A, successful lymphocyte isolation (n=24), and group B, incomplete isolation (n=27). We compared the backgrounds of the samples between the groups to reveal crucial elements in the successful isolation of lymphocytes residing in the gastrointestinal tract. Comparison between the groups revealed lymphocyte isolation success rates differed between biopsy sites. Isolation was most successful in samples from the duodenum (8/9, 88.9%), followed by the ileum (4/8, 50.0%), large intestine (4/11, 36.4%), and stomach (8/23, 34.8%). Tacrolimus was used more frequently in group B (92.6%) than in group A (62.5%) (p=0.015). Logistic regression analysis revealed that isolation from the duodenum or ileum was a significant factor for successful isolation, while tacrolimus use was not statistically significant. In conclusion, the duodenum and ileum are more suitable sites than the stomach and colorectum for acquiring samples for flow cytometry.
Keywords flow cytometry stem cell transplantation transplantation-associated microangiopathy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 347
End Page 357
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635134
Web of Science KeyUT 001163659800002
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Otsuka, Motoyuki|
Keywords autoimmune gastritis esophagogastroduodenoscopy genetic predisposition lymphocyte oxidative stress
Published Date 2023-06-21
Publication Title Current Issues in Molecular Biology
Volume volume45
Issue issue7
Publisher MDPI
Start Page 5263
End Page 5275
ISSN 1467-3037
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 37504250
DOI 10.3390/cimb45070334
Web of Science KeyUT 001035130200001
Related Url isVersionOf https://doi.org/10.3390/cimb45070334
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Kagawa, Shunsuke| Inoo, Shoko| Otsuka, Motoyuki|
Keywords immune checkpoint inhibitor chemotherapy-induced diarrhea immune-related adverse event colitis colonoscopy collagenous colitis
Published Date 2023-05-25
Publication Title Cureus
Volume volume15
Issue issue5
Publisher Springer
Start Page e39466
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Iwamuro et al.
File Version publisher
PubMed ID 37378156
DOI 10.7759/cureus.39466
Web of Science KeyUT 001023091300016
Related Url isVersionOf https://doi.org/10.7759/cureus.39466
FullText URL fulltext20230708-01.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro| Okada, Kazuya| Notohara, Kenji| Fujii, Keiko| Fujii, Nobuharu|
Keywords mantle cell lymphoma lacrimal gland autologous peripheral blood stem cell transplantation breast cancer tracheal and bronchial infiltration
Published Date 2023-07-05
Publication Title Journal of Investigative Medicine High Impact Case Reports
Volume volume11
Publisher SAGE Publications
ISSN 2324-7096
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 American Federation for Medical Research
File Version publisher
PubMed ID 37403948
DOI 10.1177/23247096231185483
Related Url isVersionOf https://doi.org/10.1177/23247096231185483
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Okada, Hiroyuki|
Keywords Diagnosis Diffuse large B-cell lymphoma Duodenal neoplasms Esoph-agogastroduodenoscopy Follicular lymphoma Gastrointestinal lymphoma
Published Date 2023-03-28
Publication Title World Journal of Gastroenterology
Volume volume29
Issue issue12
Publisher Baishideng Publishing Group
Start Page 1852
End Page 1862
ISSN 1007-9327
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37032723
DOI 10.3748/wjg.v29.i12.1852
Web of Science KeyUT 000982154800007
Related Url isVersionOf https://doi.org/10.3748/wjg.v29.i12.1852
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Urata, Haruo| Iwasa, Satoshi| Tanaka, Takehiro| Kawahara, Yoshiro| Okada, Horoyuki|
Keywords fluorescence microscopy esophagogastroduodenoscopy scanning electron microscopy analysis lanthanum carbonate hyperphosphatemia
Published Date 2022-10-26
Publication Title Cureus
Volume volume14
Issue issue10
Publisher Springer
Start Page e30729
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Iwamuro et al.
File Version publisher
PubMed ID 36447703
DOI 10.7759/cureus.30729
Web of Science KeyUT 000978541800040
Related Url isVersionOf https://doi.org/10.7759/cureus.30729