FullText URL fulltext.pdf
Author Iwamuro, Masaya| Takahashi, Takahide| Ota, Yoko| Tanaka, Takehiro| Asada, Noboru| Yano, Shuya| Uka, Mayu| Nakamura, Rei| Baba, Yuki| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki|
Published Date 2020-04-09
Publication Title Case Reports in Gastrointestinal Medicine
Volume volume2020
Publisher Hindawi
Start Page 7947540
ISSN 2090-6528
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 Masaya Iwamuro et al.
File Version publisher
PubMed ID 32328319
DOI 10.1155/2020/7947540
Web of Science KeyUT 000528921300002
Related Url isVersionOf https://doi.org/10.1155/2020/7947540
JaLCDOI 10.18926/AMO/58271
FullText URL 74_2_129.pdf
Author Fukuma, Shogo| Shinya, Takayoshi| Soh, Junichi| Fukuhara, Ryuichiro| Ogawa, Nanako| Higaki, Fumiyo| Tanaka, Takehiro| Ichihara, Eiki| Hiraki, Takao| Toyooka, Shinichi| Kanazawa, Susumu|
Abstract The aim of this study was to explore enhancement patterns of different types of primary lung cancers on 2-phase dynamic computed tomography (CT). This study included 217 primary lung cancer patients (141 adenocarcinomas [ADs], 48 squamous cell carcinomas [SCCs], 20 small cell lung carcinomas [SCLCs], and 8 others) who were examined using a 2-phase dynamic scan. Regions of interest were identified and mean enhancement values were calculated. After excluding the 20 SCLCs because these lesions had different clinical stages from the other cancer types, the mean attenuation values and subtractions between phases were compared between types of non-small cell lung carcinomas (NSCLCs) using the Kruskal–Wallis test. Late phase attenuation and attenuation of the late minus unenhanced phase (LMU) of SCCs were significantly higher than those of ADs (p<0.05). To differentiate SCC and AD in the late phase, a threshold of 80.21 Hounsfield units (HU) gave 52.9% accuracy. In LMU, a threshold of 52.16 HU gave 59.3% accuracy. Dynamic lung CT has the potential to aid in differentiating among NSCLC types.
Keywords differentiation dynamic computed tomography primary lung cancer enhancement pattern
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-04
Volume volume74
Issue issue2
Publisher Okayama University Medical School
Start Page 129
End Page 135
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32341587
Web of Science KeyUT 000528278500006
NAID 120006839450
JaLCDOI 10.18926/AMO/58270
FullText URL 74_2_123.pdf
Author Fukuhara, Ryuichiro| Shinya, Takayoshi| Fukuma, Shogo| Ogawa, Nanako| Masaoka, Yoshihisa| Tanaka, Takehiro| Marunaka, Hidenori| Arioka, Tadashi| Hiraki, Takao| Kaji, Mitsumasa| Kanazawa, Susumu|
Abstract The aim of this study was to evaluate the ability of pretreatment 90-min 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) to predict the extranodular spread of lymph node metastases in oral squamous cell carcinoma. We retrospectively reviewed the cases of 56 patients who underwent pretreatment 18F-FDG PET/CT and surgery with neck dissection. Maximum standardized uptake value, metabolic tumor volume, and total lesion glycolysis were measured for the 56 primary sites and maximum standardized uptake value was measured for 115 lymph node levels. Extranodular spread was present at 9 lymph node levels in 7 patients. Significant differences were found in metabolic tumor volume and total lesion glycolysis of the primary site, and in lymph node maximum standardized uptake value, between patients with and without extranodular spread (p<0.05). Combining primary site total lesion glycolysis and lymph node maximum standardized uptake volume at their respective optimal cutoffs, the sensitivity, specificity, and accuracy for predicting extranodular spread were 89%, 92%, and 92%, respectively. Pretreatment 18F-FDG PET/CT is useful for predicting extranodular spread in patients with oral squamous cell carcinoma. The combined use of primary site total lesion glycolysis and lymph node maximum standardized uptake value showed greater predictive value than either predictor singly.
Keywords 18F-fluorodeoxyglucose positron emission tomography/computed tomography extranodular spread metastasis oral squamous cell carcinoma
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-04
Volume volume74
Issue issue2
Publisher Okayama University Medical School
Start Page 123
End Page 128
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32341586
Web of Science KeyUT 000528278500005
NAID 120006839449
FullText URL JCEH59_4_168.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro|
Keywords Intraocular lymphoma central nervous system lymphoma CD5 vitrectomy cell block diffuse large B-cell lymphoma
Published Date 2019-12-22
Publication Title Journal of Clinical and Experimental Hematopathology
Volume volume59
Issue issue4
Publisher Japanese Society for Lymphoratic Tissue Research
Start Page 168
End Page 174
ISSN 1346-4280
NCID AA11556796
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 The Japanese Society for Lymphoreticular Tissue Research
File Version publisher
PubMed ID 31611509
DOI 10.3960/jslrt.19019
Web of Science KeyUT 000503881900003
Related Url isVersionOf https://doi.org/10.3960/jslrt.19019
FullText URL SR9_1_4633.pdf
Author Morihiro, Toshiaki| Kuroda, Shinji| Kanaya, Nobuhiko| Kakiuchi, Yoshihiko| Kubota, Tetsushi| Aoyama, Katsuyuki| Tanaka, Takehiro| Kikuch, Satoru| Nagasaka, Takeshi| Nishizaki, Masahiko| Kagawa, Shunsuke| Tazawa, Hiroshi| Fujiwara, Toshiyoshi|
Published Date 2019-3-15
Publication Title Scientific Reports
Volume volume9
Publisher Nature Publishing Group
Start Page 4633
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2019
File Version publisher
PubMed ID 30874607
DOI 10.1038/s41598-019-41177-2
Web of Science KeyUT 000461303000015
Related Url isVersionOf https://doi.org/10.1038/s41598-019-41177-2
FullText URL JIMHICR2019.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro| Yamasaki, Osamu|
Keywords BRAF inhibitor BRAF mutation MEK inhibitor PET/CT dabrafenib lacrimal sac malignant melanoma trametinib
Note UNSP 2324709619888052|
Published Date 2019-11-20
Publication Title Journal of Investigative Medicine High Impact Case Reports
Volume volume7
Publisher Sage Publications
Start Page 1
End Page 6
ISSN 2324-7096
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version publisher
PubMed ID 31747798
DOI 10.1177/2324709619888052
Web of Science KeyUT 000498954100001
Related Url isVersionOf https://doi.org/10.1177/2324709619888052
FullText URL ecancermedicalscience2019_933.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Nishida, Kenji| Kanzaki, Hiromitsu| Kawano, Seiji| Kawahara, Yoshiro| Yoshino, Tadashi| Okada, Hiroyuki|
Keywords follicular gastritis gastric neoplasms gastrointestinal endoscope mucosa-associated lymphoid tissue lymphoma nodular gastritis
Published Date 2019-06-03
Publication Title ecancermedicalscience
Volume volume13
Publisher CANCER INTELLIGENCE
Start Page 933
ISSN 1754-6605
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © the authors
File Version publisher
PubMed ID 31281430
DOI 10.3332/ecancer.2019.933
Web of Science KeyUT 000472729000001
Related Url isVersionOf https://doi.org/10.3332/ecancer.2019.933
FullText URL GRP_8159072.pdf
Author Iwamuro, Masaya| Aoyama, Yuki| Suzuki, Seiyuu| Kobayashi, Sayo| Toyokawa, Tatsuya| Moritou, Yuki| Hori, Shinichiro| Matsueda, Kazuhiro| Yoshioka, Masao| Tanaka, Takehiro| Okada, Hiroyuki|
Published Date 2019-09-08
Publication Title Gastroenterology Research and Practice
Publisher Hindawi
Start Page 8159072
ISSN 1687-6121
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders Copyright © 2019 Masaya Iwamuro et al.
File Version publisher
PubMed ID 31582972
DOI 10.1155/2019/8159072
Web of Science KeyUT 000487588000001
Related Url isVersionOf https://doi.org/10.1016/bs.aiip.2019.01.001
JaLCDOI 10.18926/AMO/57377
FullText URL 73_5_457.pdf
Author Iwamuro, Masaya| Takahara, Masahiro| Yamazaki, Tatsuhiro| Tanaka, Takehiro| Kondo, Yoshitaka| Hiraoka, Sakiko| Okada, Hiroyuki|
Abstract A 60-year-old Caucasian male was diagnosed with lung adenocarcinoma and multiple metastases to the bone, spleen, and brain. He underwent radiotherapy for the brain and lumbar spine metastases, plus chemotherapy (cisplatin and pemetrexed). The chemotherapy was discontinued due to vomiting and hyponatremia, and nivolumab was then administered. Eight months later, 18F-fluorodeoxyglucose positron emission tomography showed tracer uptake in the colon. Colonoscopy revealed a reddish multinodular polyp in the sigmoid colon. The polyp showed irregular microvessels. No colonic mucosal surface structures were observed. Colonic metastasis of the lung carcinoma was highly suspected; the polyp was therefore surgically removed. The histological analysis revealed granulation tissue and suppurative inflammation without neoplastic changes. We diagnosed the lesion as a granulation polyp. Despite the difficulty in diagnosing these lesions due to their rarity and similarity to metastatic colon tumors, we suggest that recognizing the endoscopic features of the polyp surface may allow a preoperative diagnosis.
Keywords colonoscopy colonic neoplasms granulation polyp
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2019-10
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 457
End Page 461
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649373
Web of Science KeyUT 000491886600012
Author Shinya, Takayoshi| Masaoka, Yoshihisa| Sando, Motohiro| Tanabe, Shin| Okamoto, Soichiro| Ihara, Hiroki| Tanaka, Takehiro| Otani, Shinji| Hiraki, Takao| Kanazawa, Susumu|
Keywords Solitary fibrous tumor (SFT) Intrapulmonary Computed tomography (CT)
Published Date 2019-06
Publication Title Radiology Case Reports
Volume volume14
Issue issue6
Publisher Elsevier
Start Page 755
End Page 758
ISSN 1930-0433
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 The Authors.
File Version publisher
PubMed ID 30992735
DOI 10.1016/j.radcr.2019.03.023
Related Url isVersionof https://doi.org/10.1016/j.radcr.2019.03.023
FullText URL DLD51_1_168.pdf
Author Iwamuro, Masaya| Urata, Haruo| Tanaka, Takehiro| Okada, Hiroyuki|
Published Date 2019-01-31
Publication Title Digestive and Liver Disease
Volume volume51
Issue issue1
Publisher Elsevier
Start Page 168
ISSN 15908658
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2018 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
File Version author
PubMed ID 30145054
DOI 10.1016/j.dld.2018.07.031
Web of Science KeyUT 000454119300026
Related Url isVersionOf https://doi.org/10.1016/j.dld.2018.07.031
FullText URL blood_119_1_285.pdf
Author Nishimori, Hisakazu| Maeda, Yoshinobu| Teshima, Takanori| Sugiyama, Haruko| Kobayashi, Koichiro| Yamasuji, Yoshiko| Kadohisa, Sachiyo| Uryu, Hidetaka| Takeuchi, Kengo| Tanaka, Takehiro| Yoshino, Tadashi| Iwakura, Yoichiro| Tanimoto, Mitsune|
Note This research was originally published in Blood. 2012. © the American Society of Hematology.|
Published Date 2012-01-05
Publication Title Blood
Volume volume119
Issue issue1
Start Page 285
End Page 295
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version publisher
PubMed ID 22077062
DOI 10.1182/blood-2011-01-332478
Web of Science KeyUT 000299012400035
Related Url https://doi.org/10.1182/blood-2011-01-332478
FullText URL K0005304 other1.pdf
Author Igawa, Takuro| Sato, Yasuharu| Takata, Katsuyoshi| Iwaki, Noriko| Tanaka, Takehiro| Asano, Naoko| Maeda, Yoshinobu| Orita, Yorihisa| Nakamura, Naoya| Nakamura, Shigeo| Yoshino, Tadashi|
Keywords Cyclin D2 CD5 Diffuse large B-cell lymphoma
Note 学位審査副論文|
Published Date 2013-05-15
Publication Title Diagnostic Pathology
Volume volume8
Publisher BioMed Central
Start Page 81
ISSN 1746-1596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version publisher
PubMed ID 23675804
DOI 10.1186/1746-1596-8-81
Web of Science KeyUT 000319266300002
Related Url https://doi.org/10.1186/1746-1596-8-81 http://ousar.lib.okayama-u.ac.jp/54287
JaLCDOI 10.18926/AMO/54977
FullText URL 71_2_97.pdf
Author Iwamuro, Masaya| Kondo, Eisei| Tanaka, Takehiro| Hagiya, Hideharu| Kawano, Seiji| Kawahara, Yoshiro| Otsuka, Fumio| Okada, Hiroyuki|
Abstract We retrospectively analyzed the cases of 14 patients (9 women, 5 men, mean age: 51.6 years) with cytomegalovirus (CMV) involvement in the esophagus, stomach, and/or duodenum diagnosed at a single center, to determine their endoscopic features and clinical backgrounds. Thirteen patients (92.9%) had hematologic disease; the other had rheumatoid arthritis. Of the former, 12 patients underwent allogeneic hematopoietic stem cell transplantation, and 9 of these patients had graft-versus-host disease (GVHD) before undergoing esophagogastroduodenoscopy (EGD). All 14 patients had been taking one or more immunosuppressive agents including cyclosporine (n=10), corticosteroids (n=9), mycophenolic acid (n=6), tacrolimus (n=3), and methotrexate (n=1). Tests for CMV antigenemia were positive in 11 patients (78.6%). EGD examinations revealed esophageal (n=3), gastric (n=9), and duodenal involvement (n=6). Macroscopically, esophageal lesions by CMV infection presented as redness (n=1), erosions (n=1), and ulcers (n=1). Gastric lesions manifested as redness (n=7), erosions (n=3), exfoliated mucosa (n=2), and verrucous erosions (n=1). Mucosal appearances in the duodenum varied: redness (n=2), ulcers (n=2), multiple erosions (n=2), single erosion (n=1), edema (n=1). CMV was detected even in the intact duodenal mucosa (n=1). In conclusion, physicians must recall the relevance of CMV infection when any mucosal alterations exist in the upper gastrointestinal tract of immunosuppressed patients.
Keywords cytomegalovirus duodenum esophagogastroduodenoscopy esophagus stomach
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2017-04
Volume volume71
Issue issue2
Publisher Okayama University Medical School
Start Page 97
End Page 104
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28420890
Author Iwamuro, Masaya| Urata, Haruo| Tanaka, Takehiro| Ando, Akemi| Nada, Takahiro| Kimura, Kosuke| Yamauchi, Kenji| Kusumoto, Chiaki| Otsuka, Fumio| Okada, Hiroyuki|
Published Date 2017-02
Publication Title Acta Medica Okayama
Volume volume71
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/AMO/54828
JaLCDOI 10.18926/AMO/54817
FullText URL 70_6_511.pdf
Author Gobara, Hideo| Hiraki, Takao| Iguchi, Toshihiro| Fujiwara, Hiroyasu| Nagasaka, Takeshi| Kishimoto, Hiroyuki| Tanaka, Takehiro| Kanazawa, Susumu|
Abstract An 87-year-old Japanese man underwent percutaneous cryoablation (PCA) therapy for his renal cell tumor. We displaced the colon from the tumor using hydrodissection. Computed tomography (CT) immediately after PCA was indicative of iceball extension to the colon wall, and a discontinuous enhancement of the colon wall was observed. We therefore performed an emergency surgery. On laparotomy, we observed a dark-purple area on the affected area of the colon, and the resected specimen showed focal, deep ulceration on the mucosal surface. Photomicrography revealed mucosal necrosis, submucosal hemorrhage, and necrotic foci in the muscularis propria, corresponding to the discontinuous colon wall enhancement on CT and the deep ulceration and dark-purple area on laparotomy. He recovered from surgery and was discharged without any complications.
Keywords bowel injury complication cryoablation renal cell carcinoma thermal ablation
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2016-12
Volume volume70
Issue issue6
Publisher Okayama University Medical School
Start Page 511
End Page 514
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28003679
JaLCDOI 10.18926/AMO/54815
FullText URL 70_6_503.pdf
Author Kanazawa, Yui| Yamashita, Yuka| Fujiwara, Mitsuhiro| Muraoka, Michiko| Washio, Kana| Kanamitsu, Kiichiro| Ishida, Hisashi| Nakano, Takae| Yamada, Miho| Horibe, Keizo| Tanaka, Takehiro| Yoshino, Tadashi| Shimada, Akira|
Abstract Childhood anaplastic large cell lymphoma (ALCL) accounts for approx. 10–30 of cases of non-Hodgkin lymphoma, and the ALCL99 study reported 60–75 disease-free survival; however, a relatively high relapse rate was observed (25–30 ). We report 2 patients with Stage III ALCL who relapsed 6–18 months after the end of ALCL99 chemotherapy. A retrospective molecular analysis identified the nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) fusion gene in the first diagnostic bone marrow samples taken from both patients. However, antibodies against the ALK protein appeared to be relatively low in the serum of both patients (×100 and ×750). An increase in chemotherapy intensity may be beneficial if Stage III ALCL patients are shown to be NPM-ALK chimera-positive in the first diagnostic bone marrow sample.
Keywords ALCL NPM-ALK fusion lymphoma
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2016-12
Volume volume70
Issue issue6
Publisher Okayama University Medical School
Start Page 503
End Page 506
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28003677
Author Gotoda, Tatsuhiro| Kawano, Seiji| Kono, Yoshiyasu| Miura, Kou| Kanzaki, Hiromitsu| Iwamuro, Masaya| Kawahara, Yoshiro| Tanaka, Takehiro| Yoshino, Tadashi| Shirakawad, Yasuhiro| Tabata, Masahiro| Tanimoto, Mitsune| Okada, Hiroyuki|
Published Date 2016-12-01
Publication Title Journal of Okayama Medical Association
Volume volume128
Issue issue3
Content Type Journal Article
Author Iwamuro, Masaya| Okada, Hiroyuki| Harada, Keita| Kanzaki, Hiromitsu| Hori, Keisuke| Kita, Masahide| Kawano, Seiji| Kawahara, Yoshiro| Tanaka, Takehiro| Yamamoto, Kazuhide|
Published Date 2016-12-01
Publication Title Journal of Okayama Medical Association
Volume volume128
Issue issue3
Content Type Journal Article
JaLCDOI 10.18926/AMO/54504
FullText URL 70_4_279.pdf
Author Nishimura, Yoshito| Iwamuro, Masaya| Ocho, Kazuki| Hasegawa, Kou| Kimura, Kosuke| Hanayama, Yoshihisa| Kondo, Eisei| Tanaka, Takehiro| Otsuka, Fumio|
Abstract A 61-year-old Japanese man with IgG4-related autoimmune pancreatitis was referred to our hospital because of perspiration during food intake. Abdominal computed tomography (CT) with contrast media revealed multiple mesenteric lymphadenopathies. An open surgical abdominal biopsy and subsequent histopathological analysis revealed abnormally large lymphoid cells that were negative for CD3, CD5, and c-myc and positive for CD20 and bcl-2, leading to a diagnosis of diffuse large B-cell lymphoma. Here, we discuss the risk of malignancies, particularly malignant lymphoma in patients with IgG4-related disease. The importance of pathological analysis to reach the appropriate diagnosis in such cases should be emphasized.
Keywords IgG4-related disease autoimmune pancreatitis immunophenotyping diffuse large B-cell lymphoma
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2016-08
Volume volume70
Issue issue4
Publisher Okayama University Medical School
Start Page 279
End Page 283
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 27549673
Web of Science KeyUT 000384748600008