FullText URL fulltext.pdf
Author Tanaka, Keiko| Sugiyama, Hitoshi| Morinaga, Hiroshi| Onishi, Akifumi| Tanabe, Katsuyuki| Uchida, Haruhito A.| Maruyama, Hiroki| Wada, Jun|
Keywords Fabry disease R112H mutation migalastat proteinuria chronic kidney disease
Published Date 2024-06-06
Publication Title Frontiers in Medicine
Volume volume11
Publisher Frontiers Media
Start Page 1383309
ISSN 2296-858X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Tanaka, Sugiyama, Morinaga, Onishi, Tanabe, Uchida, Maruyama and Wada.
File Version publisher
PubMed ID 38903807
DOI 10.3389/fmed.2024.1383309
Web of Science KeyUT 001250041200001
Related Url isVersionOf https://doi.org/10.3389/fmed.2024.1383309
FullText URL fulltext.pdf
Author Fukushima, Kazuhiko| Uchida, Haruhito A.| Fuchimoto, Yasuko| Mifune, Tomoyo| Watanabe, Mayu| Tsuji, Kenji| Tanabe, Katsuyuki| Kinomura, Masaru| Kitamura, Shinji| Miyamoto, Yosuke| Wada, Sae| Koyanagi, Taisaku| Sugiyama, Hitoshi| Kishimoto, Takumi| Wada, Jun|
Keywords lupus nephritis lupus pneumonitis silicosis SLE
Published Date 2022-02-18
Publication Title Medicine
Volume volume101
Issue issue7
Publisher Lippincott Williams & Wilkins
Start Page e28872
ISSN 0025-7974
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 the Author(s).
File Version publisher
PubMed ID 35363197
DOI 10.1097/MD.0000000000028872
Web of Science KeyUT 000776738500059
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000028872
FullText URL fulltext20220413-7.pdf
Author Mifune, Tomoyo| Tanabe, Katsuyuki| Nakashima, Yuri| Tanimura, Satoshi| Sugiyama, Hitoshi| Sato, Yasufumi| Wada, Jun|
Keywords Vasohibin-1 Microtubules Detyrosination Podocytes
Note © 2022 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.bbrc.2022.02.047] . |
Published Date 2022-4
Publication Title Biochemical and Biophysical Research Communications
Volume volume599
Publisher Elsevier BV
Start Page 93
End Page 99
ISSN 0006-291X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Elsevier Inc.
File Version author
PubMed ID 35180473
DOI 10.1016/j.bbrc.2022.02.047
Web of Science KeyUT 000759467800001
Related Url isVersionOf https://doi.org/10.1016/j.bbrc.2022.02.047
FullText URL fulltext.pdf
Author Tanabe, Katsuyuki| Matsuoka-Uchiyama, Natsumi| Mifune, Tomoyo| Kawakita, Chieko| Sugiyama, Hitoshi| Wada, Jun|
Keywords corticosteroid drug-induced interstitial nephritis eosinophils mycophenolate mofetil polypharmacy
Published Date 2021-12-17
Publication Title Medicine
Volume volume100
Issue issue50
Publisher Lippincott Williams & Wilkins
Start Page e28252
ISSN 0025-7974
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 the Author(s).
File Version publisher
PubMed ID 34918693
DOI 10.1097/MD.0000000000028252
Web of Science KeyUT 000731129100044
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000028252
FullText URL fulltext20210721-2.pdf figure20210721-2.pdf
Author Watari, Shogo| Araki, Motoo| Wada, Koichiro| Yoshinaga, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Kobayashi, Yasuyuki| Takeuchi, Hidemi| Tanabe, Katsuyuki| Kitagawa, Masashi| Morinaga, Hiroshi| Kitamura, Shinji| Sugiyama, Hitoshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo|
Note © 2021 Published by Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.transproceed.2021.03.043] . |
Published Date 2021-4-28
Publication Title Transplantation Proceedings
Volume volume53
Issue issue5
Publisher Elsevier BV
Start Page 1494
End Page 1500
ISSN 0041-1345
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 33931247
DOI 10.1016/j.transproceed.2021.03.043
Web of Science KeyUT 000668604400017
Related Url isVersionOf https://doi.org/10.1016/j.transproceed.2021.03.043
FullText URL fulltext.pdf
Author Yoshinaga, Kasumi| Araki, Motoo| Wada, Koichiro| Sekito, Takanori| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Yasuyuki| Tanabe, Katsuyuki| Takeuchi, Hidemi| Kitagawa, Masashi| Kitamura, Shinji| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo|
Keywords diabetes mellitus kidney function kidney transplantation marginal donor
Published Date 2021-06-08
Publication Title Immunity Inflammation and Disease
Publisher Wiley
ISSN 2050-4527
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Authors.
File Version publisher
PubMed ID 34102025
NAID 120007053366
DOI 10.1002/iid3.470
Web of Science KeyUT 000658836600001
Related Url isVersionOf https://doi.org/10.1002/iid3.470
FullText URL fulltext.pdf
Author Matsuoka, Natsumi| Watanabe, Haruki| Kurooka, Naoko| Kato, Sumari| Higashi, Chika| Tanabe, Katsuyuki| Kinomura, Masaru| Fujii, Nobuharu| Sada, Ken-Ei| Sugiyama, Hitoshi| Wada, Jun|
Keywords acute kidney injury Evans syndrome autoimmune hemolytic anemia
Published Date 2021-04-01
Publication Title Internal Medicine
Volume volume60
Issue issue7
Publisher Japanese Society of Internal Medicine
Start Page 1055
End Page 1060
ISSN 0918-2918
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 33116016
NAID 120007042384
DOI 10.2169/internalmedicine.5976-20
Web of Science KeyUT 000637009100013
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.5976-20
FullText URL fulltext.pdf
Author Tanabe, Katsuyuki| Kanzaki, Hiromitsu| Wada, Takahira| Nakashima, Yuri| Sugiyama, Hitoshi| Okada, Hiroyuki| Wada, Jun|
Keywords case report gastric cancer IgA nephropathy nivolumab steroid
Published Date 2020-05-22
Publication Title Medicine
Volume volume99
Issue issue21
Publisher Lippincott, Williams & Wilkins
Start Page e20464
ISSN 0025-7974
NCID AA00728867
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 the Author(s).
File Version publisher
PubMed ID 32481351
DOI 10.1097/MD.0000000000020464
Web of Science KeyUT 000551508200106
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000020464
FullText URL fulltext.pdf
Author Miyake, Hiromasa| Tanabe, Katsuyuki| Tanimura, Satoshi| Nakashima, Yuri| Morioka, Tomoyo| Masuda, Kana| Sugiyama, Hitoshi| Sato, Yasufumi| Wada, Jun|
Keywords acute kidney injury ischemia-reperfusion oxidative stress vasohibin-2 peritubular capillaries
Published Date 2020-06-26
Publication Title International Journal of Molecular Sciences
Volume volume21
Issue issue12
Publisher MDPI
Start Page 4545
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 by the authors.
File Version publisher
PubMed ID 32604722
DOI 10.3390/ijms21124545
Web of Science KeyUT 000549478900001
Related Url isVersionOf https://doi.org/10.3390/ijms21124545
FullText URL fulltext.pdf
Author Ogawa-Akiyama, Ayu| Sugiyama, Hitoshi| Kitagawa, Masashi| Tanaka, Keiko| Kano, Yuzuki| Mise, Koki| Otaka, Nozomu| Tanabe, Katsuyuki| Morinaga, Hiroshi| Kinomura, Masaru| Uchida, Haruhito A.| Wada, Jun|
Published Date 2020-01-24
Publication Title PLoS ONE
Volume volume15
Issue issue1
Publisher Public Library of Science
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 Ogawa-Akiyama et al.
File Version publisher
PubMed ID 31978139
DOI 10.1371/journal.pone.0228337
Web of Science KeyUT 000534599100142
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0228337
JaLCDOI 10.18926/AMO/57953
FullText URL 74_1_53.pdf
Author Kubota, Risa| Araki, Motoo| Wada, Koichiro| Kawamura, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Ariyoshi, Yuichi| Iwata, Takehiro| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Kano, Yuzuki| Kitagawa, Masashi| Tanabe, Katsuyuki| Sugiyama, Hitoshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo|
Abstract We investigated the feasibility of robotic renal autotransplantation (RAT) in a porcine model to reduce invasiveness of RAT. Five pigs underwent robotic RAT using the da Vinci® robotic system. A robotic left nephrectomy was performed in all cases. Robotic RAT was performed on the left side in all but one case. Four ports were used. In 3 cases, the kidney was taken out through the GelPort® and irrigated on ice with Ringer’s solution. In 2 cases, a complete intracorporeal robotic RAT was performed. An end-to-side anastomosis was performed between the renal vein and the external iliac vein and between the renal artery and the external iliac artery. Ureteroneocystostomy was also performed in 2 cases. All cases were performed robotically without open conversion. The median (IQR) console time was 3.1 (0.7) h, and the operative time was 3.8 (1.1) h. The estimated blood loss was 30 (0) ml. The warm ischemia time was 4.0 (0.2) min, and the cold ischemia time was 97 (17) min. Intracorporeal transarterial hypothermic renal perfusion was feasible in the 2 complete intracorporeal robotic RAT cases by using a perfusion catheter through a laparoscopic port. Robotic RAT has the potential to be a new minimally invasive substitute for conventional open surgery.
Keywords renal autotransplantation robotic porcine model transplantation
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-02
Volume volume74
Issue issue1
Publisher Okayama University Medical School
Start Page 53
End Page 58
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32099249
Web of Science KeyUT 000516606200008
NAID 120006795620
JaLCDOI 10.18926/AMO/55434
FullText URL 71_5_369.pdf
Author Arata, Yuka| Tanabe, Katsuyuki| Hinamoto, Norikazu| Yamasaki, Hiroko| Sugiyama, Hitoshi| Maeshima, Yohei| Kanomata, Naoki| Sato, Yasufumi| Wada, Jun|
Abstract Several angiogenesis-related factors are known to play important roles in the pathogenesis of kidney disease. Vasohibin-2 (VASH-2) was recently reported as a novel proangiogenic factor. Although VASH-2 was demonstrated to accelerate tumor angiogenesis, its roles in non-tumor processes including renal disease have not been well elucidated yet. Here, we performed a retrospective study including an immunohistochemical analysis of human kidney biopsy specimens from 82 Japanese patients with a variety of kidney diseases, and we evaluated the correlations between the immunoreactivity of VASH-2 and the patients’ clinicopathological parameters. VASH-2 immunoreactivity was detected in varying degrees in renal tubules as well as in peritubular capillaries and vasa recta. The cortical and medullary tubule VASH-2+ scores were correlated with the presence of hypertension, and the medullary tubule VASH-2+ score was significantly correlated with the blood glucose (p=0.029, r=0.35) and hemoglobin A1c levels (p=0.0066, r=0.39). Moreover, decreased VASH-2+ scores in the vasa recta were associated with reduced renal function (p=0.0003). These results suggest that VASH-2 could play an important role in the pathogenesis of renal diseases, and that VASH-2 is closely associated with hypertension and impaired glucose tolerance.
Keywords vasohibin-2 kidney disease vasa recta medullary tubules
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2017-10
Volume volume71
Issue issue5
Publisher Okayama University Medical School
Start Page 369
End Page 380
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 29042694
JaLCDOI 10.18926/AMO/54507
FullText URL 70_4_295.pdf
Author Araki, Motoo| Wada, Koichiro| Mitsui, Yosuke| Kubota, Risa| Yoshioka, Takashi| Ariyoshi, Yuichi| Kobayashi, Yasuyuki| Kitagawa, Masashi| Tanabe, Katsuyuki| Sugiyama, Hiroshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Hotta, Katsuyuki| Nasu, Yasutomo|
Abstract Although graft survival following renal transplantation (RTx) has improved, outcomes following highrisk RTx are variable. Preexisting antibodies, including donor-specific antibodies (DSA), play an important role in graft dysfunction and survival. We have designed a study to investigate the safety and efficacy of anti-CD20 monoclonal antibodies (rituximab) in high-risk RTx recipients. Major eligibility criteria include: 1) major and minor ABO blood group mismatch, 2) positive DSA. Thirty-five patients will receive 200 mg/body of rituximab. The primary endpoint is the incidence of B cell depletion. This study will clarify whether rituximab is efficacious in improving graft survival in high-risk RTx recipients.
Keywords end-stage renal disease immunosuppression kidney transplantation
Amo Type Clinical Study Protocols
Publication Title Acta Medica Okayama
Published Date 2016-08
Volume volume70
Issue issue4
Publisher Okayama University Medical School
Start Page 295
End Page 297
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 27549676
Web of Science KeyUT 000384748600011
JaLCDOI 10.18926/AMO/53117
FullText URL 69_1_1.pdf
Author Watatani, Hiroyuki| Yamasaki, Hiroko| Maeshima, Yohei| Nasu, Tatsuyo| Hinamoto, Norikazu| Ujike, Haruyo| Sugiyama, Hitoshi| Sakai, Yoshiki| Tanabe, Katsuyuki| Makino, Hirofumi|
Abstract Diabetic nephropathy is the most common pathological disorder predisposing patients to end-stage renal disease. Considering the increasing prevalence of type 2 diabetes mellitus worldwide, novel therapeutic approaches are urgently needed. ONO-1301 is a novel sustained-release prostacyclin analog that inhibits thromboxane A2 synthase. Here we examined the therapeutic effects of the intermittent administration of slow-release ONO-1301 (SR-ONO) on diabetic nephropathy in obese type 2 diabetes mice, as well as its direct effects on mesangial cells. The subcutaneous injection of SR-ONO (3mg/kg) every 3 wks did not affect the obesity or hyperglycemia in the db/db obese mice used as a model of type 2 diabetes, but it significantly ameliorated their albuminuria, glomerular hypertrophy, glomerular accumulation of type IV collagen, and monocyte/macrophage infiltration, and also the increase of TGF-β1, α-smooth muscle actin (α-SMA) and MCP-1 compared to vehicle treatment. In cultured mouse mesangial cells, ONO-1301 concentration-dependently suppressed the increases in TGF-β, type IV collagen, α-SMA, MCP-1 and fibronectin induced by high ambient glucose, at least partly through prostacyclin (PGI2) receptor-mediated signaling. Taken together, these results suggest the potential therapeutic efficacy of the intermittent administration of SR-ONO against type 2 diabetic nephropathy, possibly through protective effects on mesangial cells.
Keywords prostacyclin ONO-1301 diabetic nephropathy TGF-β1 diabetes mellitus
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2015-02
Volume volume69
Issue issue1
Publisher Okayama University Medical School
Start Page 1
End Page 15
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2015 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25703166
Web of Science KeyUT 000349740300001
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/53128
JaLCDOI 10.18926/AMO/52788
FullText URL 68_4_219.pdf
Author Hinamoto, Norikazu| Maeshima, Yohei| Saito, Daisuke| Yamasaki, Hiroko| Tanabe, Katsuyuki| Nasu, Tatsuyo| Watatani, Hiroyuki| Ujike, Haruyo| Kinomura, Masaru| Sugiyama, Hitoshi| Sonoda, Hikaru| Kanomata, Naoki| Sato, Yasufumi| Makino, Hirofumi|
Abstract Experimental studies have demonstrated the involvement of angiogenesis-related factors in the progression of chronic kidney disease (CKD). There have so far been no reports investigating the distribution and clinical roles of Vasohibin-1 (VASH-1), a negative feedback regulator of angiogenesis, in CKD. We recruited 54 Japanese CKD patients and 6 patients who had normal renal tissues excised due to localized renal cell carcinoma. We evaluated the correlations between the renal expression level of VASH-1 and the clinical/histological parameters. VASH-1 was observed in renal endothelial/mesangial cells, crescentic lesions and interstitial inflammatory cells. Significant positive correlations were observed between 1) crescent formation and the number of VASH-1+ cells in the glomerulus (r=0.48, p=0.001) or cortex (r=0.64, p<0.0001), 2) interstitial cell infiltration and the number of VASH-1+ cells in the cortex (r=0.34, p=0.02), 3) the glomerular VEGFR-2+ area and the number of VASH-1+ cells in the glomerulus (r=0.44, p=0.01) or medulla (r=0.63, p=0.01). These results suggest that the renal levels of VASH-1 may be affected by local inflammation, crescentic lesions and VEGFR-2.
Keywords chronic kidney disease inflammation Vasohibin-1 VEGF-A VEGFR-2
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2014-08
Volume volume68
Issue issue4
Publisher Okayama University Medical School
Start Page 219
End Page 233
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25145408
Web of Science KeyUT 000340687500004
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/52824