| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Fukushima, Kazuhiko| Uchida, Haruhito A.| Fuchimoto, Yasuko| Mifune, Tomoyo| Watanabe, Mayu| Tsuji, Kenji| Tanabe, Katsuyuki| Kinomura, Masaru| Kitamura, Shinji| Miyamoto, Yosuke| Wada, Sae| Koyanagi, Taisaku| Sugiyama, Hitoshi| Kishimoto, Takumi| Wada, Jun| |
| キーワード | lupus nephritis lupus pneumonitis silicosis SLE |
| 発行日 | 2022-02-18 |
| 出版物タイトル | Medicine |
| 巻 | 101巻 |
| 号 | 7号 |
| 出版者 | Lippincott Williams & Wilkins |
| 開始ページ | e28872 |
| ISSN | 0025-7974 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 the Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 35363197 |
| DOI | 10.1097/MD.0000000000028872 |
| Web of Science KeyUT | 000776738500059 |
| 関連URL | isVersionOf https://doi.org/10.1097/MD.0000000000028872 |
| フルテキストURL | fulltext20220413-7.pdf |
|---|---|
| 著者 | Mifune, Tomoyo| Tanabe, Katsuyuki| Nakashima, Yuri| Tanimura, Satoshi| Sugiyama, Hitoshi| Sato, Yasufumi| Wada, Jun| |
| キーワード | Vasohibin-1 Microtubules Detyrosination Podocytes |
| 備考 | © 2022 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.bbrc.2022.02.047] . | |
| 発行日 | 2022-4 |
| 出版物タイトル | Biochemical and Biophysical Research Communications |
| 巻 | 599巻 |
| 出版者 | Elsevier BV |
| 開始ページ | 93 |
| 終了ページ | 99 |
| ISSN | 0006-291X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 Elsevier Inc. |
| 論文のバージョン | author |
| PubMed ID | 35180473 |
| DOI | 10.1016/j.bbrc.2022.02.047 |
| Web of Science KeyUT | 000759467800001 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.bbrc.2022.02.047 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tanabe, Katsuyuki| Matsuoka-Uchiyama, Natsumi| Mifune, Tomoyo| Kawakita, Chieko| Sugiyama, Hitoshi| Wada, Jun| |
| キーワード | corticosteroid drug-induced interstitial nephritis eosinophils mycophenolate mofetil polypharmacy |
| 発行日 | 2021-12-17 |
| 出版物タイトル | Medicine |
| 巻 | 100巻 |
| 号 | 50号 |
| 出版者 | Lippincott Williams ＆ Wilkins |
| 開始ページ | e28252 |
| ISSN | 0025-7974 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 the Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 34918693 |
| DOI | 10.1097/MD.0000000000028252 |
| Web of Science KeyUT | 000731129100044 |
| 関連URL | isVersionOf https://doi.org/10.1097/MD.0000000000028252 |
| フルテキストURL | fulltext20210721-2.pdf figure20210721-2.pdf |
|---|---|
| 著者 | Watari, Shogo| Araki, Motoo| Wada, Koichiro| Yoshinaga, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Kobayashi, Yasuyuki| Takeuchi, Hidemi| Tanabe, Katsuyuki| Kitagawa, Masashi| Morinaga, Hiroshi| Kitamura, Shinji| Sugiyama, Hitoshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 備考 | © 2021 Published by Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.transproceed.2021.03.043] . | |
| 発行日 | 2021-4-28 |
| 出版物タイトル | Transplantation Proceedings |
| 巻 | 53巻 |
| 号 | 5号 |
| 出版者 | Elsevier BV |
| 開始ページ | 1494 |
| 終了ページ | 1500 |
| ISSN | 0041-1345 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 33931247 |
| DOI | 10.1016/j.transproceed.2021.03.043 |
| Web of Science KeyUT | 000668604400017 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.transproceed.2021.03.043 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yoshinaga, Kasumi| Araki, Motoo| Wada, Koichiro| Sekito, Takanori| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Yasuyuki| Tanabe, Katsuyuki| Takeuchi, Hidemi| Kitagawa, Masashi| Kitamura, Shinji| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| キーワード | diabetes mellitus kidney function kidney transplantation marginal donor |
| 発行日 | 2021-06-08 |
| 出版物タイトル | Immunity Inflammation and Disease |
| 出版者 | Wiley |
| ISSN | 2050-4527 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 34102025 |
| NAID | 120007053366 |
| DOI | 10.1002/iid3.470 |
| Web of Science KeyUT | 000658836600001 |
| 関連URL | isVersionOf https://doi.org/10.1002/iid3.470 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Matsuoka, Natsumi| Watanabe, Haruki| Kurooka, Naoko| Kato, Sumari| Higashi, Chika| Tanabe, Katsuyuki| Kinomura, Masaru| Fujii, Nobuharu| Sada, Ken-Ei| Sugiyama, Hitoshi| Wada, Jun| |
| キーワード | acute kidney injury Evans syndrome autoimmune hemolytic anemia |
| 発行日 | 2021-04-01 |
| 出版物タイトル | Internal Medicine |
| 巻 | 60巻 |
| 号 | 7号 |
| 出版者 | Japanese Society of Internal Medicine |
| 開始ページ | 1055 |
| 終了ページ | 1060 |
| ISSN | 0918-2918 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Japanese Society of Internal Medicine |
| 論文のバージョン | publisher |
| PubMed ID | 33116016 |
| NAID | 120007042384 |
| DOI | 10.2169/internalmedicine.5976-20 |
| Web of Science KeyUT | 000637009100013 |
| 関連URL | isVersionOf https://doi.org/10.2169/internalmedicine.5976-20 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tanabe, Katsuyuki| Kanzaki, Hiromitsu| Wada, Takahira| Nakashima, Yuri| Sugiyama, Hitoshi| Okada, Hiroyuki| Wada, Jun| |
| キーワード | case report gastric cancer IgA nephropathy nivolumab steroid |
| 発行日 | 2020-05-22 |
| 出版物タイトル | Medicine |
| 巻 | 99巻 |
| 号 | 21号 |
| 出版者 | Lippincott, Williams & Wilkins |
| 開始ページ | e20464 |
| ISSN | 0025-7974 |
| NCID | AA00728867 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 the Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 32481351 |
| DOI | 10.1097/MD.0000000000020464 |
| Web of Science KeyUT | 000551508200106 |
| 関連URL | isVersionOf https://doi.org/10.1097/MD.0000000000020464 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Miyake, Hiromasa| Tanabe, Katsuyuki| Tanimura, Satoshi| Nakashima, Yuri| Morioka, Tomoyo| Masuda, Kana| Sugiyama, Hitoshi| Sato, Yasufumi| Wada, Jun| |
| キーワード | acute kidney injury ischemia-reperfusion oxidative stress vasohibin-2 peritubular capillaries |
| 発行日 | 2020-06-26 |
| 出版物タイトル | International Journal of Molecular Sciences |
| 巻 | 21巻 |
| 号 | 12号 |
| 出版者 | MDPI |
| 開始ページ | 4545 |
| ISSN | 1422-0067 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 32604722 |
| DOI | 10.3390/ijms21124545 |
| Web of Science KeyUT | 000549478900001 |
| 関連URL | isVersionOf https://doi.org/10.3390/ijms21124545 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Ogawa-Akiyama, Ayu| Sugiyama, Hitoshi| Kitagawa, Masashi| Tanaka, Keiko| Kano, Yuzuki| Mise, Koki| Otaka, Nozomu| Tanabe, Katsuyuki| Morinaga, Hiroshi| Kinomura, Masaru| Uchida, Haruhito A.| Wada, Jun| |
| 発行日 | 2020-01-24 |
| 出版物タイトル | PLoS ONE |
| 巻 | 15巻 |
| 号 | 1号 |
| 出版者 | Public Library of Science |
| ISSN | 1932-6203 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 Ogawa-Akiyama et al. |
| 論文のバージョン | publisher |
| PubMed ID | 31978139 |
| DOI | 10.1371/journal.pone.0228337 |
| Web of Science KeyUT | 000534599100142 |
| 関連URL | isVersionOf https://doi.org/10.1371/journal.pone.0228337 |
| JaLCDOI | 10.18926/AMO/57953 |
|---|---|
| フルテキストURL | 74_1_53.pdf |
| 著者 | Kubota, Risa| Araki, Motoo| Wada, Koichiro| Kawamura, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Ariyoshi, Yuichi| Iwata, Takehiro| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Kano, Yuzuki| Kitagawa, Masashi| Tanabe, Katsuyuki| Sugiyama, Hitoshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 抄録 | We investigated the feasibility of robotic renal autotransplantation (RAT) in a porcine model to reduce invasiveness of RAT. Five pigs underwent robotic RAT using the da Vinci® robotic system. A robotic left nephrectomy was performed in all cases. Robotic RAT was performed on the left side in all but one case. Four ports were used. In 3 cases, the kidney was taken out through the GelPort® and irrigated on ice with Ringer’s solution. In 2 cases, a complete intracorporeal robotic RAT was performed. An end-to-side anastomosis was performed between the renal vein and the external iliac vein and between the renal artery and the external iliac artery. Ureteroneocystostomy was also performed in 2 cases. All cases were performed robotically without open conversion. The median (IQR) console time was 3.1 (0.7) h, and the operative time was 3.8 (1.1) h. The estimated blood loss was 30 (0) ml. The warm ischemia time was 4.0 (0.2) min, and the cold ischemia time was 97 (17) min. Intracorporeal transarterial hypothermic renal perfusion was feasible in the 2 complete intracorporeal robotic RAT cases by using a perfusion catheter through a laparoscopic port. Robotic RAT has the potential to be a new minimally invasive substitute for conventional open surgery. |
| キーワード | renal autotransplantation robotic porcine model transplantation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 53 |
| 終了ページ | 58 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099249 |
| Web of Science KeyUT | 000516606200008 |
| NAID | 120006795620 |
| JaLCDOI | 10.18926/AMO/55434 |
|---|---|
| フルテキストURL | 71_5_369.pdf |
| 著者 | Arata, Yuka| Tanabe, Katsuyuki| Hinamoto, Norikazu| Yamasaki, Hiroko| Sugiyama, Hitoshi| Maeshima, Yohei| Kanomata, Naoki| Sato, Yasufumi| Wada, Jun| |
| 抄録 | Several angiogenesis-related factors are known to play important roles in the pathogenesis of kidney disease. Vasohibin-2 (VASH-2) was recently reported as a novel proangiogenic factor. Although VASH-2 was demonstrated to accelerate tumor angiogenesis, its roles in non-tumor processes including renal disease have not been well elucidated yet. Here, we performed a retrospective study including an immunohistochemical analysis of human kidney biopsy specimens from 82 Japanese patients with a variety of kidney diseases, and we evaluated the correlations between the immunoreactivity of VASH-2 and the patients’ clinicopathological parameters. VASH-2 immunoreactivity was detected in varying degrees in renal tubules as well as in peritubular capillaries and vasa recta. The cortical and medullary tubule VASH-2+ scores were correlated with the presence of hypertension, and the medullary tubule VASH-2+ score was significantly correlated with the blood glucose (p=0.029, r=0.35) and hemoglobin A1c levels (p=0.0066, r=0.39). Moreover, decreased VASH-2+ scores in the vasa recta were associated with reduced renal function (p=0.0003). These results suggest that VASH-2 could play an important role in the pathogenesis of renal diseases, and that VASH-2 is closely associated with hypertension and impaired glucose tolerance. |
| キーワード | vasohibin-2 kidney disease vasa recta medullary tubules |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-10 |
| 巻 | 71巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 369 |
| 終了ページ | 380 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29042694 |
| JaLCDOI | 10.18926/AMO/54507 |
|---|---|
| フルテキストURL | 70_4_295.pdf |
| 著者 | Araki, Motoo| Wada, Koichiro| Mitsui, Yosuke| Kubota, Risa| Yoshioka, Takashi| Ariyoshi, Yuichi| Kobayashi, Yasuyuki| Kitagawa, Masashi| Tanabe, Katsuyuki| Sugiyama, Hiroshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Hotta, Katsuyuki| Nasu, Yasutomo| |
| 抄録 | Although graft survival following renal transplantation (RTx) has improved, outcomes following highrisk RTx are variable. Preexisting antibodies, including donor-specific antibodies (DSA), play an important role in graft dysfunction and survival. We have designed a study to investigate the safety and efficacy of anti-CD20 monoclonal antibodies (rituximab) in high-risk RTx recipients. Major eligibility criteria include: 1) major and minor ABO blood group mismatch, 2) positive DSA. Thirty-five patients will receive 200 mg/body of rituximab. The primary endpoint is the incidence of B cell depletion. This study will clarify whether rituximab is efficacious in improving graft survival in high-risk RTx recipients. |
| キーワード | end-stage renal disease immunosuppression kidney transplantation |
| Amo Type | Clinical Study Protocols |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-08 |
| 巻 | 70巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 295 |
| 終了ページ | 297 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27549676 |
| Web of Science KeyUT | 000384748600011 |
| JaLCDOI | 10.18926/AMO/53117 |
|---|---|
| フルテキストURL | 69_1_1.pdf |
| 著者 | Watatani, Hiroyuki| Yamasaki, Hiroko| Maeshima, Yohei| Nasu, Tatsuyo| Hinamoto, Norikazu| Ujike, Haruyo| Sugiyama, Hitoshi| Sakai, Yoshiki| Tanabe, Katsuyuki| Makino, Hirofumi| |
| 抄録 | Diabetic nephropathy is the most common pathological disorder predisposing patients to end-stage renal disease. Considering the increasing prevalence of type 2 diabetes mellitus worldwide, novel therapeutic approaches are urgently needed. ONO-1301 is a novel sustained-release prostacyclin analog that inhibits thromboxane A2 synthase. Here we examined the therapeutic effects of the intermittent administration of slow-release ONO-1301 (SR-ONO) on diabetic nephropathy in obese type 2 diabetes mice, as well as its direct effects on mesangial cells. The subcutaneous injection of SR-ONO (3mg/kg) every 3 wks did not affect the obesity or hyperglycemia in the db/db obese mice used as a model of type 2 diabetes, but it significantly ameliorated their albuminuria, glomerular hypertrophy, glomerular accumulation of type IV collagen, and monocyte/macrophage infiltration, and also the increase of TGF-β1, α-smooth muscle actin (α-SMA) and MCP-1 compared to vehicle treatment. In cultured mouse mesangial cells, ONO-1301 concentration-dependently suppressed the increases in TGF-β, type IV collagen, α-SMA, MCP-1 and fibronectin induced by high ambient glucose, at least partly through prostacyclin (PGI2) receptor-mediated signaling. Taken together, these results suggest the potential therapeutic efficacy of the intermittent administration of SR-ONO against type 2 diabetic nephropathy, possibly through protective effects on mesangial cells. |
| キーワード | prostacyclin ONO-1301 diabetic nephropathy TGF-β1 diabetes mellitus |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-02 |
| 巻 | 69巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 1 |
| 終了ページ | 15 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 25703166 |
| Web of Science KeyUT | 000349740300001 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/53128 |
| JaLCDOI | 10.18926/AMO/52788 |
|---|---|
| フルテキストURL | 68_4_219.pdf |
| 著者 | Hinamoto, Norikazu| Maeshima, Yohei| Saito, Daisuke| Yamasaki, Hiroko| Tanabe, Katsuyuki| Nasu, Tatsuyo| Watatani, Hiroyuki| Ujike, Haruyo| Kinomura, Masaru| Sugiyama, Hitoshi| Sonoda, Hikaru| Kanomata, Naoki| Sato, Yasufumi| Makino, Hirofumi| |
| 抄録 | Experimental studies have demonstrated the involvement of angiogenesis-related factors in the progression of chronic kidney disease (CKD). There have so far been no reports investigating the distribution and clinical roles of Vasohibin-1 (VASH-1), a negative feedback regulator of angiogenesis, in CKD. We recruited 54 Japanese CKD patients and 6 patients who had normal renal tissues excised due to localized renal cell carcinoma. We evaluated the correlations between the renal expression level of VASH-1 and the clinical/histological parameters. VASH-1 was observed in renal endothelial/mesangial cells, crescentic lesions and interstitial inflammatory cells. Significant positive correlations were observed between 1) crescent formation and the number of VASH-1+ cells in the glomerulus (r＝0.48, p＝0.001) or cortex (r＝0.64, p＜0.0001), 2) interstitial cell infiltration and the number of VASH-1+ cells in the cortex (r＝0.34, p＝0.02), 3) the glomerular VEGFR-2+ area and the number of VASH-1+ cells in the glomerulus (r＝0.44, p＝0.01) or medulla (r＝0.63, p＝0.01). These results suggest that the renal levels of VASH-1 may be affected by local inflammation, crescentic lesions and VEGFR-2. |
| キーワード | chronic kidney disease inflammation Vasohibin-1 VEGF-A VEGFR-2 |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-08 |
| 巻 | 68巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 219 |
| 終了ページ | 233 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 25145408 |
| Web of Science KeyUT | 000340687500004 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/52824 |