Ohtsuki, Takashi - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

LRP4 and Agrin Are Modulated by Cartilage Degeneration and Involved in β-Catenin Signaling in Human Articular Chondrocytes

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Author	Naniwa, Shuichi\| Nishida, Keiichiro\| Yoshida, Aki\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Ohtsuki, Takashi\| Hotta, Yoshifumi\| Shimizu, Noriyuki\| Ichikawa, Chinatsu\| Lin, Deting\| Otsuka, Noriaki\| Ozaki, Toshifumi\|
Keywords	osteoarthritis chondrocyte mechanical stress LRP4 Agrin β-catenin SOX9
Published Date	2025-01-24
Publication Title	International Journal of Molecular Sciences
Volume	volume26
Issue	issue3
Publisher	MDPI
Start Page	1007
ISSN	1661-6596
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 by the authors.
File Version	publisher
PubMed ID	39940775
DOI	10.3390/ijms26031007
Web of Science KeyUT	001418599900001
Related Url	isVersionOf https://doi.org/10.3390/ijms26031007

Novel Drug Delivery Particles Can Provide Dual Effects on Cancer "Theranostics" in Boron Neutron Capture Therapy

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Author	Fithroni, Abdul Basith\| Inoue, Haruki\| Zhou, Shengli\| Hakim, Taufik Fatwa Nur\| Tada, Takashi\| Suzuki, Minoru\| Sakurai, Yoshinori\| Ishimoto, Manabu\| Yamada, Naoyuki\| Sauriasari, Rani\| Sauerwein, Wolfgang A. G.\| Watanabe, Kazunori\| Ohtsuki, Takashi\| Matsuura, Eiji\|
Keywords	boron neutron capture therapy (BNCT) dual therapeutic effects Lactosome ® hydrophobic boron compound neutron irradiation theranostics
Published Date	2025-01-06
Publication Title	Cells
Volume	volume14
Issue	issue1
Publisher	MDPI
Start Page	60
ISSN	2073-4409
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 by the authors.
File Version	publisher
PubMed ID	39791761
DOI	10.3390/cells14010060
Web of Science KeyUT	001394869200001
Related Url	isVersionOf https://doi.org/10.3390/cells14010060

Distribution and Incorporation of Extracellular Vesicles into Chondrocytes and Synoviocytes

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Author	Ohtsuki, Takashi\| Sato, Ikumi\| Takashita, Ren\| Kodama, Shintaro\| Ikemura, Kentaro\| Opoku, Gabriel\| Watanabe, Shogo\| Furumatsu, Takayuki\| Yamada, Hiroshi\| Ando, Mitsuru\| Akiyoshi, Kazunari\| Nishida, Keiichiro\| Hirohata, Satoshi\|
Keywords	extracellular vesicles (EVs) chondrocytes synoviocytes osteoarthritis (OA)
Published Date	2024-11-06
Publication Title	International Journal of Molecular Sciences
Volume	volume25
Issue	issue22
Publisher	MDPI
Start Page	11942
ISSN	1661-6596
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
DOI	10.3390/ijms252211942
Web of Science KeyUT	001365437300001
Related Url	isVersionOf https://doi.org/10.3390/ijms252211942

In Vitro Study of Tumor-Homing Peptide-Modified Magnetic Nanoparticles for Magnetic Hyperthermia

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Author	Zhou, Shengli\| Tsutsumiuchi, Kaname\| Imai, Ritsuko\| Miki, Yukiko\| Kondo, Anna\| Nakagawa, Hiroshi\| Watanabe, Kazunori\| Ohtsuki, Takashi\|
Keywords	tumor-homing peptide magnetic hyperthermia magnetic nanoparticles ferroptosis tumor-specific delivery
Published Date	2024-06-03
Publication Title	Molecules
Volume	volume29
Issue	issue11
Publisher	MDPI
Start Page	2632
ISSN	1420-3049
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	38893510
DOI	10.3390/molecules29112632
Web of Science KeyUT	001245732000001
Related Url	isVersionOf https://doi.org/10.3390/molecules29112632

Pyrene-Modified Cyclic Peptides Detect Cu2+ Ions by Fluorescence in Water

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Author	Maekawa, Yuhi\| Sakura, Sora\| Furutani, Yuji\| Fujihara, Rento\| Sugime, Hisashi\| Ohtsuki, Takashi\| Kitamatsu, Mizuki\|
Keywords	peptide pyrene metal ion fluorescence
Published Date	2024-04-07
Publication Title	Processes
Volume	volume12
Issue	issue4
Publisher	MDPI
Start Page	746
ISSN	2227-9717
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
DOI	10.3390/pr12040746
Web of Science KeyUT	001211366700001
Related Url	isVersionOf https://doi.org/10.3390/pr12040746

Photo-dependent cytosolic delivery of shRNA into a single blastomere in a mouse embryo

FullText URL	fulltext.pdf
Author	Ikawa, Yuka\| Wakai, Takuya\| Funahashi, Hiroaki\| Soe, Tet Htut\| Watanabe, Kazunori\| Ohtsuki, Takashi\|
Note	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-40361-9\|
Published Date	2023-08-11
Publication Title	Scientific Reports
Volume	volume13
Issue	issue1
Publisher	nature portfolio
Start Page	13050
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2023
File Version	publisher
PubMed ID	37567923
DOI	10.1038/s41598-023-40361-9
Web of Science KeyUT	001068298400054
Related Url	isVersionOf https://doi.org/10.1038/s41598-023-40361-9

FRET probe for detecting two mutations in one EGFR mRNA

FullText URL	fulltext20230619-02.pdf
Author	Thu, Myat\| Yanai, Kouta\| Shigeto, Hajime\| Yamamura, Shohei\| Watanabe, Kazunori\| Ohtsuki, Takashi\|
Published Date	2023
Publication Title	Analyst
Volume	volume148
Issue	issue11
Publisher	Royal Society of Chemistry (RSC)
Start Page	2626
End Page	2632
ISSN	0003-2654
NCID	AA00524823
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Royal Society of Chemistry 2023
File Version	publisher
PubMed ID	37191032
DOI	10.1039/d3an00554b
Web of Science KeyUT	000988019800001
Related Url	isVersionOf https://doi.org/10.1039/D3AN00554B

Novel Self-Forming Nanosized DDS Particles for BNCT: Utilizing A Hydrophobic Boron Cluster and Its Molecular Glue Effect

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Author	Fithroni, Abdul Basith\| Kobayashi, Kazuko\| Uji, Hirotaka\| Ishimoto, Manabu\| Akehi, Masaru\| Ohtsuki, Takashi\| Matsuura, Eiji\|
Keywords	boron neutron capture therapy (BNCT) biologically self-degradable amphipathic polymer (Lactosome) hydrophobic boron cluster carborane isomers or o-carborane alkylated derivatives molecular glue effect
Published Date	2022-10-21
Publication Title	CELLS
Volume	volume11
Issue	issue20
Publisher	MDPI
Start Page	3307
ISSN	2073-4409
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 by the authors.
File Version	publisher
PubMed ID	36291173
DOI	10.3390/cells11203307
Web of Science KeyUT	000872497500001
Related Url	isVersionOf https://doi.org/10.3390/cells11203307

Ultrasound-dependent RNAi using TatU1A-rose bengal conjugate

FullText URL	fulltext20220630-10.pdf
Author	Sumi, Nanako\| Nagahiro, Shota\| Nakata, Eiji\| Watanabe, Kazunori\| Ohtsuki, Takashi\|
Keywords	Ultrasound Sonosensitizer Rose Bengal RNAi RNA delivery
Note	© 2022 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.bmcl.2022.128767. This fulltext is available in May 2024. \|
Published Date	2022-07
Publication Title	Bioorganic & Medicinal Chemistry Letters
Volume	volume68
Publisher	Elsevier BV
Start Page	128767
ISSN	0960-894X
NCID	AA1079577X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 Elsevier Ltd.
File Version	author
PubMed ID	35513220
DOI	10.1016/j.bmcl.2022.128767
Web of Science KeyUT	000800009100005
Related Url	isVersionOf https://doi.org/10.1016/j.bmcl.2022.128767

Potential of a Novel Chemical Compound Targeting Matrix Metalloprotease-13 for Early Osteoarthritis: An In Vitro Study

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Author	Inagaki, Junko\| Nakano, Airi\| Hatipoglu, Omer Faruk\| Ooka, Yuka\| Tani, Yurina\| Miki, Akane\| Ikemura, Kentaro\| Opoku, Gabriel\| Ando, Ryosuke\| Kodama, Shintaro\| Ohtsuki, Takashi\| Yamaji, Hirosuke\| Yamamoto, Shusei\| Katsuyama, Eri\| Watanabe, Shogo\| Hirohata, Satoshi\|
Keywords	osteoarthritis matrix metalloproteinase MMP13 ADAMTS9 expression screening chondrocytes
Published Date	2022-02-28
Publication Title	International Journal Of Molecular Sciences
Volume	volume23
Issue	issue5
Publisher	MDPI
Start Page	2681
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 by the authors.
File Version	publisher
PubMed ID	35269821
DOI	10.3390/ijms23052681
Web of Science KeyUT	000773522200001
Related Url	isVersionOf https://doi.org/10.3390/ijms23052681

Photocontrolled apoptosis induction using precursor miR-664a and an RNA carrier-conjugated with photosensitizer

FullText URL	fulltext.pdf
Author	Watanabe, Kazunori\| Nawachi, Tomoko\| Okutani, Ruriko\| Ohtsuki, Takashi\|
Published Date	2021-07-22
Publication Title	scientific reports
Volume	volume11
Issue	issue1
Publisher	Nature Portfolio
Start Page	14936
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021
File Version	publisher
PubMed ID	34294789
DOI	10.1038/s41598-021-94249-7
Web of Science KeyUT	000682800400009
Related Url	isVersionOf https://doi.org/10.1038/s41598-021-94249-7

Osteopontin silencing attenuates bleomycin-induced murine pulmonary fibrosis by regulating epithelial-mesenchymal transition

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Author	Hatipoglu, Omer Faruk\| Uctepe, Eyyup\| Opoku, Gabriel\| Wake, Hidenori\| Ikemura, Kentaro\| Ohtsuki, Takashi\| Inagaki, Junko\| Gunduz, Mehmet\| Gunduz, Esra\| Watanabe, Shogo\| Nishinaka, Takashi\| Takahashi, Hideo\| Hirohata, Satoshi\|
Keywords	Pulmonary fibrosis Osteopontin Epithelial-mesenchymal transition
Published Date	2021-07
Publication Title	Biomedicine & Pharmacotherapy
Volume	volume139
Publisher	Elsevier France-Editions Scientifiques Medicales e
Start Page	111633
ISSN	0753-3322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Author(s).
File Version	publisher
DOI	10.1016/j.biopha.2021.111633
Web of Science KeyUT	000663683300007
Related Url	isVersionOf https://doi.org/10.1016/j.biopha.2021.111633

Inhibition of HSF1 and SAFB Granule Formation Enhances Apoptosis Induced by Heat Stress

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Author	Watanabe, Kazunori\| Ohtsuki, Takashi\|
Keywords	heat shock response nuclear stress bodies HSF1 granules SAFB granules liquid-liquid phase separation
Published Date	2021-05-07
Publication Title	International Journal of Molecular Sciences
Volume	volume22
Issue	issue9
Publisher	MDPI
Start Page	4982
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	34067147
DOI	10.3390/ijms22094982
NAID	120007042387
Web of Science KeyUT	000650646500001
Related Url	isVersionOf https://doi.org/10.3390/ijms22094982

Lactosome-Conjugated siRNA Nanoparticles for Photo-Enhanced Gene Silencing in Cancer Cells

FullText URL	fulltext20210421_2.pdf
Author	Lim, Melissa Siaw Han\| Nishiyama, Yuki\| Ohtsuki, Takashi\| Watanabe, Kazunori\| Kobuchi, Hirotsugu\| Kobayashi, Kazuko\| Matsuura, Eiji\|
Keywords	Lactosome ABCG2 siRNA Cancer siRNA delivery Photodynamic therapy Polymeric micelle Photosensitizer Photochemical internalization
Note	©2021 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.xphs.2021.01.026] . \|
Published Date	2021-04-30
Publication Title	Journal of Pharmaceutical Sciences
Volume	volume110
Publisher	Elsevier
Start Page	1788
End Page	1798
ISSN	00223549
NCID	AA00704450
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	33529684
DOI	10.1016/j.xphs.2021.01.026
Web of Science KeyUT	000631863100036
Related Url	isVersionOf https://doi.org/10.1016/j.xphs.2021.01.026

A Novel 89Zr-labeled DDS Device Utilizing Human IgG Variant (scFv): “Lactosome” Nanoparticle-Based Theranostics for PET Imaging and Targeted Therapy

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Author	Lim, Melissa Siaw Han\| Ohtsuki, Takashi\| Takenaka, Fumiaki\| Kobayashi, Kazuko\| Akehi, Masaru\| Uji, Hirotaka\| Kobuchi, Hirotsugu\| Sasaki, Takanori\| Ozeki, Eiichi\| Matsuura, Eiji\|
Keywords	theranostics single chain variable fragment of IgG (scFv) drug delivery system (DDS) photodynamic therapy (PDT) PET imaging accelerated blood clearance (ABC) cell penetrating peptide (CPP) siRNA ATP-binding cassette subfamily G member 2 (ABCG2)
Published Date	2021-02-18
Publication Title	Life
Volume	volume11
Issue	issue2
Publisher	MDPI
Start Page	158
ISSN	2075-1729
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	33670777
DOI	10.3390/life11020158
Web of Science KeyUT	000622756700001
Related Url	isVersionOf https://doi.org/10.3390/life11020158

Photoinduced Endosomal Escape Mechanism: A View from Photochemical Internalization Mediated by CPP-Photosensitizer Conjugates

FullText URL	fulltext.pdf
Author	Soe, Tet Htut\| Watanabe, Kazunori\| Ohtsuki, Takashi\|
Keywords	photochemical internalization photosensitizer cell-penetrating peptide endosome membrane
Published Date	2020-12-23
Publication Title	Molecules
Volume	volume26
Issue	issue1
Publisher	MDPI
Start Page	36
ISSN	1420-3049
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	33374732
DOI	10.3390/molecules26010036
Web of Science KeyUT	000606148000001
Related Url	isVersionOf https://doi.org/10.3390/molecules26010036

Cell cycle dependence of apoptosis photo-triggered using peptide-photosensitizer conjugate

FullText URL	fulltext.pdf
Author	Kim, Hyungjin\| Watanabe, Sho\| Kitamatsu, Mizuki\| Watanabe, Kazunori\| Ohtsuki, Takashi\|
Keywords	Biological techniques Biotechnology
Published Date	2020-11-05
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature Research
Start Page	19087
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	33154435
DOI	10.1038/s41598-020-76100-7
Web of Science KeyUT	000587665200004
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-76100-7

Induction of CEMIP in Chondrocytes by Inflammatory Cytokines: Underlying Mechanisms and Potential Involvement in Osteoarthritis

FullText URL	fulltext.pdf
Author	Ohtsuki, Takashi\| Hatipoglu, Omer F.\| Asano, Keiichi\| Inagaki, Junko\| Nishida, Keiichiro\| Hirohata, Satoshi\|
Keywords	cell migration-inducing hyaluronidase 1 (CEMIP) chondrocyte hyaluronan mechanical strain nuclear factor kappa B (NF-kappa B) osteoarthritis
Published Date	2020-04-29
Publication Title	International Journal of Molecular Sciences
Volume	volume21
Issue	issue9
Publisher	MDPI
Start Page	3140
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	32365591
DOI	10.3390/ijms21093140
Web of Science KeyUT	000535581700111
Related Url	isVersionOf https://doi.org/10.3390/ijms21093140

Mechanical strain attenuates cytokine-induced ADAMTS9 expression via transient receptor potential vanilloid type 1

FullText URL	fulltext.pdf
Author	Ohtsuki, Takashi\| Shinaoka, Akira\| Kumagishi-Shinaoka, Kanae\| Asano, Keiichi\| Hatipoglu, Omer Faruk\| Inagaki, Junko\| Takahashi, Ken\| Oohashi, Toshitaka\| Nishida, Keiichiro\| Naruse, Keiji\| Hirohata, Satoshi\|
Published Date	2019-10-15
Publication Title	Experimental Cell Research
Volume	volume383
Issue	issue2
Publisher	Elsevier
Start Page	111556
ISSN	00144827
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 The Authors. Published by Elsevier Inc.
File Version	publisher
PubMed ID	31415758
DOI	10.1016/j.yexcr.2019.111556
Web of Science KeyUT	000488145400017
Related Url	isVersionOf https://doi.org/10.1016/j.yexcr.2019.111556

Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs

FullText URL	NatCommun_12501.pdf
Author	Ohtsuki, Takashi\| Kanzaki, Shigeto\| Nishimura, Sae\| Kunihiro, Yoshio\| Sisido, Masahiko\| Watanabe, Kazunori\|
Keywords	Molecular engineering Optogenetics
Note	This is an article published by Nature Publishing Group\|
Published Date	2016-08
Publication Title	Nature Communications
Volume	volume7
Start Page	12501
ISSN	2041-1723
NCID	AA12645905
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version	publisher
PubMed ID	27530762
DOI	10.1038/ncomms12501
Web of Science KeyUT	000381771700001
Related Url	https://doi.org/10.1038/ncomms12501