Ohashi, Kadoaki - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Plasma S100A8/A9 level predicts response to immune checkpoint inhibitors in patients with advanced non-small cell lung cancer

FullText URL	fulltext.pdf
Author	Kuribayashi, Tadahiro\| Kinoshita, Rie\| Ninomiya, Kiichiro\| Makimoto, Go\| Kubo, Toshio\| Rai, Kammei\| Ichihara, Eiki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\| Toyooka, Shinichi\| Sakaguchi, Masakiyo\| Ohashi, Kadoaki\|
Keywords	S100A8/A9 Lung cancer Immune checkpoint inhibitors
Note	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-025-87232-z\|
Published Date	2025-01-20
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Nature Portfolio
Start Page	2577
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	39833332
DOI	10.1038/s41598-025-87232-z
Web of Science KeyUT	001400880600002
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-87232-z

Successful immunotherapy with ipilimumab and nivolumab in a patient with pulmonary sclerosing pneumocytoma

FullText URL	fulltext.pdf
Author	Inukai-Motokura, Yumi\| Ninomiya, Kiichiro\| Baba, Takahiro\| Omori, Hiroki\| Takeguchi, Tetsuya\| Uno, Mari\| Ayada, Yoshiyuki\| Tanaka, Takehiro\| Maeda, Yoshinobu\| Ohashi, Kadoaki\|
Keywords	Pulmonary sclerosing pneumocytoma Ipilimumab Nivolumab Programmed cell death ligand 1 Case report
Published Date	2024-11-29
Publication Title	International Cancer Conference Journal
Volume	volume14
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	60
End Page	63
ISSN	2192-3183
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024
File Version	publisher
DOI	10.1007/s13691-024-00737-8
Web of Science KeyUT	001366705400001
Related Url	isVersionOf https://doi.org/10.1007/s13691-024-00737-8

A Prompt Diagnosis and Treatment of a Case of Nuclear Protein of the Testis Carcinoma Characterized by a Bronchial Lesion and High Serum Alpha-fetoprotein Level Following Genomic Testing

FullText URL	fulltext.pdf
Author	Matsuura, Hiroaki\| Makimoto, Go\| Oda, Naohiro\| Ninomiya, Kiichiro\| Higo, Hisao\| Fujii, Masanori\| Rai, Kammei\| Ichihara, Eiki\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\|
Keywords	NUT carcinoma BRD4-NUTM1 lung cancer alpha-fetoprotein (AFP) immune checkpoint inhibitor
Published Date	2024-10-01
Publication Title	Internal Medicine
Volume	volume63
Issue	issue19
Publisher	Japanese Society of Internal Medicine
Start Page	2655
End Page	2660
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	38403772
DOI	10.2169/internalmedicine.2938-23
Web of Science KeyUT	001344217900013
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.2938-23

Protracted coronavirus disease 2019 after chimeric antigen receptor-T cell therapy successfully treated with sequential multidrug therapy

FullText URL	fulltext.pdf
Author	Yamashita, Masahiro\| Higo, Hisao\| Fujii, Nobuharu\| Matsumoto, Chiaki\| Makimoto, Go\| Ninomiya, Kiichiro\| Fujii, Masanori\| Rai, Kammei\| Ichihara, Eiki\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Miyahara, Nobuaki\|
Keywords	Chimeric antigen receptor-T cell therapy Coronavirus disease 2019 Multidrug therapy Organizing pneumonia
Published Date	2024
Publication Title	Respiratory Medicine Case Reports
Volume	volume51
Publisher	Elsevier
Start Page	102104
ISSN	2213-0071
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Authors.
File Version	publisher
DOI	10.1016/j.rmcr.2024.102104
Web of Science KeyUT	001307936800001
Related Url	isVersionOf https://doi.org/10.1016/j.rmcr.2024.102104

Severe Cytokine Release Syndrome and Immune Effector Cell-associated Neurotoxicity Syndrome in a Man Receiving Immune Checkpoint Inhibitors for Lung Cancer

FullText URL	fulltext20240531-01.pdf
Author	Tanaka, Takaaki\| Taoka, Masataka\| Makimoto, Go\| Ninomiya, Kiichiro\| Higo, Hisao\| Fujii, Masanori\| Ichihara, Eiki\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\|
Keywords	immune checkpoint inhibitor nivolumab ipilimumab cytokine release syndrome immune effector cell-associated neurotoxicity syndrome
Published Date	2024-05-01
Publication Title	Internal Medicine
Volume	volume63
Issue	issue9
Publisher	Japanese Society of Internal Medicine
Start Page	1261
End Page	1267
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	37722894
DOI	10.2169/internalmedicine.2429-23
Web of Science KeyUT	001223220900001
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.2429-23

Concomitant osimertinib and antituberculosis therapy in an elderly patient with EGFR-mutated lung cancer and pulmonary tuberculosis: A case report

FullText URL	fulltext.pdf
Author	Matsuura, Hiroaki\| Higo, Hisao\| Kuribayashi, Tadahiro\| Tamaoki, Akihiko\| Nakasuka, Takamasa\| Uno, Mari\| Makimoto, Go\| Ninomiya, Kiichiro\| Fujii, Masanori\| Rai, Kammei\| Ichihara, Eiki\| Hotta, Katsuyuki\| Miyahara, Nobuaki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\| Ohashi, Kadoaki\|
Keywords	case report EGFR-mutated lung cancer osimertinib pulmonary tuberculosis rifampicin
Published Date	2024-05-02
Publication Title	Thoracic Cancer
Volume	volume15
Issue	issue17
Publisher	Wiley
Start Page	1390
End Page	1394
ISSN	1759-7706
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Authors.
File Version	publisher
PubMed ID	38698706
DOI	10.1111/1759-7714.15324
Web of Science KeyUT	001216948400001
Related Url	isVersionOf https://doi.org/10.1111/1759-7714.15324

CDK4/6 signaling attenuates the effect of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer

FullText URL	fulltext.pdf
Author	Hara, Naofumi\| Ichihara, Eiki\| Kano, Hirohisa\| Ando, Chihiro\| Morita, Ayako\| Nishi, Tatsuya\| Okawa, Sachi\| Nakasuka, Takamasa\| Hirabae, Atsuko\| Abe, Masaya\| Asada, Noboru\| Ninomiya, Kiichiro\| Makimoto, Go\| Fujii, Masanori\| Kubo, Toshio\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	Epidermal growth factor receptor (EGFR) non-small cell lung cancer (NSCLC) cell cycle CDK4/6 inhibitor
Published Date	2023-10-31
Publication Title	Translational Lung Cancer Research
Volume	volume12
Issue	issue10
Publisher	AME Publishing Company
ISSN	2218-6751
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Translational Lung Cancer Research.
File Version	publisher
PubMed ID	38025818
DOI	10.21037/tlcr-23-99
Web of Science KeyUT	001091030600001
Related Url	isVersionOf https://doi.org/10.21037/tlcr-23-99

Clinical characteristics of patients treated with immune checkpoint inhibitors in EGFR-mutant non-small cell lung cancer: CS-Lung-003 prospective observational registry study

FullText URL	fulltext20240226-04.pdf
Author	Kuribayashi, Tadahiro\| Ohashi, Kadoaki\| Nishii, Kazuya\| Ninomiya, Kiichiro\| Tsubata, Yukari\| Ishikawa, Nobuhisa\| Kodani, Masahiro\| Kanaji, Nobuhiro\| Yamasaki, Masahiro\| Fujitaka, Kazunori\| Kuyama, Shoichi\| Takigawa, Nagio\| Fujimoto, Nobukazu\| Kubota, Tetsuya\| Inoue, Masaaki\| Fujiwara, Keiichi\| Harita, Shingo\| Takata, Ichiro\| Takada, Kenji\| Okawa, Sachi\| Kiura, Katsuyuki\| Hotta, Katsuyuki\|
Keywords	EGFR EGFR-TKI Lung cancer Immune checkpoint inhibitors Performance status
Note	The version of record of this article, first published in Journal of Cancer Research and Clinical Oncology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00432-024-05618-4\|
Published Date	2024-02-12
Publication Title	Journal of Cancer Research and Clinical Oncology
Volume	volume150
Issue	issue2
Publisher	Springer Science and Business Media LLC
Start Page	89
ISSN	1432-1335
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024
File Version	publisher
PubMed ID	38347279
DOI	10.1007/s00432-024-05618-4
Web of Science KeyUT	001160773600002
Related Url	isVersionOf https://doi.org/10.1007/s00432-024-05618-4

Massive hemoptysis in a post-operative patient with recurrent lung cancer successfully treated by the combination therapy of Endobronchial Watanabe Spigot and bronchial artery embolization

FullText URL	fulltext.pdf
Author	Taoka, Masataka\| Makimoto, Go\| Umakoshi, Noriyuki\| Ninomiya, Kiichiro\| Higo, Hisao\| Kato, Yuka\| Fujii, Masanori\| Kubo, Toshio\| Ichihara, Eiki\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	Hemoptysis Bronchial artery embolization Endoscopic bronchial occlusion Endobronchial Watanabe Spigot
Published Date	2022
Publication Title	Respiratory Medicine Case Reports
Volume	volume38
Publisher	Elsevier
Start Page	101669
ISSN	2213-0071
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Authors.
File Version	publisher
PubMed ID	35646587
DOI	10.1016/j.rmcr.2022.101669
Web of Science KeyUT	001089212200003
Related Url	isVersionOf https://doi.org/10.1016/j.rmcr.2022.101669

Low frequency of intracranial progression in advanced NSCLC patients treated with cancer immunotherapies

FullText URL	fulltext20231004-03.pdf fig1_20231004-03.pdf fig2_20231004-03.pdf fig3_20231004-03.pdf fig4_20231004-03.pdf fig5_20231004-03.pdf Suppl20231004-03.pdf
Author	Kemmotsu, Naoya\| Ninomiya, Kiichiro\| Kunimasa, Kei\| Ishino, Takamasa\| Nagasaki, Joji\| Otani, Yoshihiro\| Michiue, Hiroyuki\| Ichihara, Eiki\| Ohashi, Kadoaki\| Inoue, Takako\| Tamiya, Motohiro\| Sakai, Kazuko\| Ueda, Youki\| Dansako, Hiromichi\| Nishio, Kazuto\| Kiura, Katsuyuki\| Date, Isao\| Togashi, Yosuke\|
Keywords	cancer immunotherapy intracranial metastasis intracranial progression memory precursor effector T cell nonsmall-cell lung cancer
Note	This is the peer reviewed version of the following article: [Kemmotsu N, Ninomiya K, Kunimasa K, et al. Low frequency of intracranial progression in advanced NSCLC patients treated with cancer immunotherapies. Int J Cancer. 2024; 154(1): 169-179. doi:10.1002/ijc.34700], which has been published in final form at [https://doi.org/10.1002/ijc.34700]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\| This fulltext file will be available in Aug. 2024.\|
Published Date	2023-08-23
Publication Title	International Journal of Cancer
Volume	volume154
Issue	issue1
Publisher	Wiley
Start Page	169
End Page	179
ISSN	0020-7136
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 UICC.
File Version	author
PubMed ID	37611176
DOI	10.1002/ijc.34700
Web of Science KeyUT	001069876600001
Related Url	isVersionOf https://doi.org/10.1002/ijc.34700

Efficacy of gilteritinib in comparison with alectinib for the treatment of ALK-rearranged non-small cell lung cancer

FullText URL	fulltext.pdf
Author	Ando, Chihiro\| Ichihara, Eiki\| Nishi, Tatsuya\| Morita, Ayako\| Hara, Naofumi\| Takada, Kenji\| Nakasuka, Takamasa\| Watanabe, Hiromi\| Kano, Hirohisa\| Nishii, Kazuya\| Makimoto, Go\| Kondo, Takumi\| Ninomiya, Kiichiro\| Fujii, Masanori\| Kubo, Toshio\| Ohashi, Kadoaki\| Matsuoka, Ken-Ichi\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	alectinib ALK gilteritinib non-small cell lung cancer TKI
Published Date	2023-09-15
Publication Title	Cancer Science
Volume	volume114
Issue	issue11
Publisher	Wiley
Start Page	4343
End Page	4354
ISSN	1347-9032
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 The Authors.
File Version	publisher
PubMed ID	37715310
DOI	10.1111/cas.15958
Web of Science KeyUT	001067479000001
Related Url	isVersionOf https://doi.org/10.1111/cas.15958

PD-1 blockade augments CD8+ T cell dependent antitumor immunity triggered by Ad-SGE-REIC in Egfr-mutant lung cancer

FullText URL	fulltext20230421-01.pdf figure20230421-01.pdf
Author	Nakasuka, Takamasa\| Ohashi, Kadoaki\| Nishii, Kazuya\| Hirabae, Atsuko\| Okawa, Sachi\| Tomonobu, Nahoko\| Takada, Kenji\| Ando, Chihiro\| Watanabe, Hiromi\| Makimoto, Go\| Ninomiya, Kiichiro\| Fujii, Masanori\| Kubo, Toshio\| Ichihara, Eiki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Kumon, Hiromi\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	EGFR mutation Non-small cell lung cancer Antitumor immunity Non-inflamed tumor Ad-SGE-REIC Gene therapy PD-1
Note	©2023 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.lungcan.2023.01.018.\| This fulltext file will be available in Apr. 2024.\|
Published Date	2023-04
Publication Title	Lung Cancer
Volume	volume178
Publisher	Elsevier BV
Start Page	1
End Page	10
ISSN	0169-5002
NCID	AA10785743
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 Elsevier B.V.
File Version	author
PubMed ID	36753780
DOI	10.1016/j.lungcan.2023.01.018
Web of Science KeyUT	000931976300001
Related Url	isVersionOf https://doi.org/10.1016/j.lungcan.2023.01.018

Successful and Prompt Treatment with Tepotinib for Lung Adenocarcinoma Harboring MET Exon 14 Skipping Mutation Combined with Lung Abscess Formation: A Case Report

FullText URL	fulltext.pdf
Author	Makimoto, Go\| Shimonishi, Atsushi\| Ohashi, Kadoaki\| Ninomiya, Kiichiro\| Higo, Hisao\| Kato, Yuka\| Fujii, Masanori\| Kubo, Toshio\| Ichihara, Eiki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	MET Tepotinib Non-small-cell lung cancer
Published Date	2022
Publication Title	Case Reports In Oncology
Volume	volume15
Issue	issue2
Publisher	Karger
Start Page	494
End Page	498
ISSN	1662-6575
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Author(s).
File Version	publisher
PubMed ID	35702678
DOI	10.1159/000524326
Web of Science KeyUT	000864085100005
Related Url	isVersionOf https://doi.org/10.1159/000524326

Pulmonary Aspergilloma and Allergic Bronchopulmonary Aspergillosis Following the 2018 Heavy Rain Event in Western Japan

FullText URL	fulltext.pdf
Author	Ando, Eri\| Nakasuka, Takamasa\| Kubo, Toshio\| Taniguchi, Akihiko\| Ninomiya, Kiichiro\| Kato, Yuka\| Ichihara, Eiki\| Ohashi, Kadoaki\| Rai, Kammei\| Hotta, Katsuyuki\| Yamane, Masaomi\| Miyahara, Nobuaki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	pulmonary aspergilloma allergic bronchopulmonary aspergillosis disaster
Published Date	2022-02-01
Publication Title	Internal Medicine
Volume	volume61
Issue	issue3
Publisher	JAPAN SOC INTERNAL MEDICINE
Start Page	379
End Page	383
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	34373373
DOI	10.2169/internalmedicine.7124-21
Web of Science KeyUT	000752787300015
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.7124-21

Identification of targetable kinases in idiopathic pulmonary fibrosis

FullText URL	fulltext.pdf
Author	Higo, Hisao\| Ohashi, Kadoaki\| Tomida, Shuta\| Okawa, Sachi\| Yamamoto, Hiromasa\| Sugimoto, Seiichiro\| Senoo, Satoru\| Makimoto, Go\| Ninomiya, Kiichiro\| Nakasuka, Takamasa\| Nishii, Kazuya\| Taniguchi, Akihiko\| Kubo, Toshio\| Ichihara, Eiki\| Hotta, Katsuyuki\| Miyahara, Nobuaki\| Maeda, Yoshinobu\| Toyooka, Shinichi\| Kiura, Katsuyuki\|
Keywords	Idiopathic pulmonary fibrosis RNA sequencing Molecular therapeutic target Personalized therapy
Published Date	2022-02-07
Publication Title	Respiratory Research
Volume	volume23
Issue	issue1
Publisher	BMC
Start Page	20
ISSN	1465-993X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2022.
File Version	publisher
PubMed ID	35130915
DOI	10.1186/s12931-022-01940-y
Web of Science KeyUT	000752386100002
Related Url	isVersionOf https://doi.org/10.1186/s12931-022-01940-y

Marginal Zone Lymphoma and Lung Adenocarcinoma with an EGFR Exon 19 E746-S752del Mutation in a Patient with IgG4-related Disease

FullText URL	fulltext.pdf
Author	Okawa, Sachi\| Rai, Kammei\| Fujii, Nobuharu\| Gion, Yuka\| Ninomiya, Kiichiro\| Kato, Yuka\| Taniguchi, Akihiko\| Kubo, Toshio\| Ichihara, Eiki\| Ohashi, Kadoaki\| Miyahara, Nobuaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	EGFR IgG4-related disease marginal zone lymphoma osimertinib
Published Date	2021-09-01
Publication Title	Internal Medicine
Volume	volume60
Issue	issue17
Publisher	The Japanese Society of Internal Medicine
Start Page	2831
End Page	2837
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	33775999
DOI	10.2169/internalmedicine.6470-20
Web of Science KeyUT	000695856000020
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.6470-20

Triple therapy with osimertinib, bevacizumab and cetuximab in EGFR‑mutant lung cancer with HIF‑1α/TGF‑α expression

FullText URL	fulltext20210810-3.pdf
Author	Nishii, Kazuya\| Ohashi, Kadoaki\| Watanabe, Hiromi\| Makimoto, Go\| Nakasuka, Takamasa\| Higo, Hisao\| Ninomiya, Kiichiro\| Kato, Yuka\| Kubo, Toshio\| Rai, Kammei\| Ichihara, Eiki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	epidermal growth factor receptor osimertinib bevacizumab cetuximab hypoxia‑inducible factor‑1α transforming growth factor‑α
Published Date	2021-7-7
Publication Title	Oncology Letters
Volume	volume22
Issue	issue3
Publisher	Spandidos Publications
Start Page	639
ISSN	1792-1074
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Nishii et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
File Version	publisher
DOI	10.3892/ol.2021.12900
Web of Science KeyUT	000678494600001
Related Url	isVersionOf https://doi.org/10.3892/ol.2021.12900

VEGFR2 blockade augments the effects of tyrosine kinase inhibitors by inhibiting angiogenesis and oncogenic signaling in oncogene-driven non-small-cell lung cancers

FullText URL	fulltext.pdf
Author	Watanabe, Hiromi\| Ichihara, Eiki\| Kayatani, Hiroe\| Makimoto, Go\| Ninomiya, Kiichiro\| Nishii, Kazuya\| Higo, Hisao\| Ando, Chihiro\| Okawa, Sachi\| Nakasuka, Takamasa\| Kano, Hirohisa\| Hara, Naofumi\| Hirabae, Atsuko\| Kato, Yuka\| Ninomiya, Takashi\| Kubo, Toshio\| Rai, Kammei\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Published Date	2021-01-07
Publication Title	Cancer science
Publisher	Wiley
ISSN	1347-9032
NCID	AA11808050
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Authors.
File Version	publisher
PubMed ID	33410241
NAID	120007008532
DOI	10.1111/cas.14801
Web of Science KeyUT	000630136900001
Related Url	isVersionOf https://doi.org/10.1111/cas.14801

Detection of epidermal growth factor receptor mutations in exhaled breath condensate using droplet digital polymerase chain reaction

FullText URL	fulltext.pdf
Author	Nishii, Kazuya\| Ohashi, Kadoaki\| Tamura, Tomoki\| Ninomiya, Kiichiro\| Matsubara, Takehiro\| Senoo, Satoru\| Kano, Hirohisa\| Watanabe, Hiromi\| Oda, Naohiro\| Makimoto, Go\| Higo, Hisao\| Kato, Yuka\| Ninomiya, Takashi\| Kubo, Toshio\| Yamamoto, Hiromasa \| Tomida, Shuta\| Hotta, Katsuyuki\| Tabata, Masahiro\| Toyooka, Shinichi\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	non-small cell lung cancer epidermal growth factor receptor mutations droplet digital PCR exhaled breath condensate EGFR-TKIs
Published Date	2020-12
Publication Title	Oncology Letters
Volume	volume20
Issue	issue6
Publisher	Spandidos Publications
Start Page	393
ISSN	1792-1074
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	publisher
PubMed ID	33193853
DOI	10.3892/ol.2020.12256
Web of Science KeyUT	000595649300005
Related Url	isVersionOf https://doi.org/10.3892/ol.2020.12256

Anaplastic Lymphoma Kinase Fusion: A Review of Therapeutic Drugs and Treatment Strategies

JaLCDOI	10.18926/AMO/60796
FullText URL	74_5_371.pdf
Author	Makimoto, Go\| Ohashi, Kadoaki\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Abstract	The prognosis of advanced non-small cell lung cancer (NSCLC) patients has improved in recent decades, especially for patients with an oncogenic driver mutation. Anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) are effective for patients with the echinoderm microtubule-associated protein-like 4-ALK fusion gene. Several ALK-TKIs have been established: the first-generation ALK-TKI, crizotinib; second-generation ALK-TKIs, alectinib and ceritinib; and third-generation ALK-TKI, lorlatinib. Some ALK-TKIs are effective for tumors that are resistant to other ALK-TKIs; however, as is known in epidermal growth factor receptormutant lung cancer, tumor resistance is inevitable. ALK-positive NSCLCs acquire resistance via various mechanisms, making it a heterogeneous disease. Therefore, it is necessary to develop next-generation treatment strategies, such as the use of next-generation ALK-TKIs for secondary mutations, or combination therapies with ALK-TKIs and other TKIs. In this review, we summarize the development and use of ALK-TKIs, prior pivotal clinical trials, and resistance mechanisms.
Keywords	lung cancer anaplastic lymphoma kinase tyrosine kinase inhibitors resistance mechanism
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2020-10
Volume	volume74
Issue	issue5
Publisher	Okayama University Medical School
Start Page	371
End Page	379
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2020 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	33106692
Web of Science KeyUT	000581970100001
NAID	120006892922