Akagi, Satoshi - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

平成25年度岡山医学会賞胸部・循環研究奨励賞（砂田賞）

Title Alternative	The 2013 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2013 Sunada Prize)
FullText URL	126_195.pdf
Author	Akagi, Satoshi\|
Abstract	受賞対象論文: Akagi S, Nakamura K, Matsubara H, Kusano KF, Kataoka N, Oto T, Miyaji K, Miura A, Ogawa A, Yoshida M, Ueda-Ishibashi H, Yutani C, Ito H：Prostaglandin I2 induces apoptosis via upregulation of Fas ligand in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. Int J Cardiol (2013) 165, 499-505.
Publication Title	岡山医学会雑誌
Published Date	2014-12-01
Volume	volume126
Issue	issue3
Start Page	195
End Page	197
ISSN	0030-1558
language	Japanese
Copyright Holders	Copyright (c) 2014 岡山医学会
File Version	publisher
DOI	10.4044/joma.126.195
NAID	130004903242

Epoprostenol Therapy for Pulmonary Arterial Hypertension

JaLCDOI	10.18926/AMO/53519
FullText URL	69_3_129.pdf
Author	Akagi, Satoshi\| Nakamura, Kazufumi\| Matsubara, Hiromi\| Ogawa, Aiko\| Sarashina, Toshihiro\| Ejiri, Kentaro\| Ito, Hiroshi\|
Abstract	Pulmonary arterial hypertension (PAH) is characterized by elevation of pulmonary artery pressure caused by pulmonary vasoconstriction and vascular remodeling, which leads to right heart failure and death. Epoprostenol (prostaglandin I2) has a potent short-acting vasodilator property, and intravenous continuous epoprostenol is therefore used for treatment of PAH. Here we review evidence for the usefulness of intravenous continuous epoprostenol therapy in patients with PAH. Epoprostenol therapy is effective in idiopathic PAH patients and in patients with PAH associated with connective tissue disease, portal hypertension or congenital heart diseases, but it is not effective in patients with pulmonary veno-occlusive disease or pulmonary capillary hemangiomatosis. High-dose epoprostenol therapy markedly improved hemodynamics in some patients with PAH, possibly due to reverse remodeling of pulmonary arteries. This therapy has several side effects and complications such as headache, hypotension and catheter-related infections. Intravenous continuous epoprostenol is an effective treatment, but there are still some problems to be resolved.
Keywords	pulmonary arterial hypertension epoprostenol high-dose complications side effects
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2015-06
Volume	volume69
Issue	issue3
Publisher	Okayama University Medical School
Start Page	129
End Page	136
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2015 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	26101188
Web of Science KeyUT	000356903000001

Feasibility of Repairing Defects Followed by Treatment with Pulmonary Hypertension-specific Drugs (Repair and Treat) in Patients with Pulmonary Hypertension Associated with Atrial Septal Defect: Study Protocol for Interventional Trial

JaLCDOI	10.18926/AMO/54600
FullText URL	70_5_397.pdf
Author	Akagi, Satoshi\| Nakamura, Kazufumi\| Akagi, Teiji\| Nakagawa, Koji\| Takaya, Yoichi\| Sarashina, Toshihiro\| Ejiri, Kentaro\| Ito, Hiroshi\|
Abstract	A treatment strategy for patients with pulmonary hypertension (PH) and atrial septal defect (ASD) remains unclear. This study was designed to evaluate the effects of initial repair of ASD followed by treatment with PH-specific drugs in patients with PH and ASD. Eligible patients receive transcatheter ASD closure followed by treatment with bosentan and sildenafil. Right heart catheterization is performed at baseline and at 12, 24 and 48 weeks. The primary endpoint is change in pulmonary artery pressure and pulmonary vascular resistance from baseline to follow-up. This study should provide valuable information to establish a therapeutic strategy for PH and ASD.
Keywords	pulmonary hypertension atrial septal defect repair and treat transcatheter closure
Amo Type	Clinical Study Protocols
Publication Title	Acta Medica Okayama
Published Date	2016-10
Volume	volume70
Issue	issue5
Publisher	Okayama University Medical School
Start Page	397
End Page	400
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2016 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	27777434
Web of Science KeyUT	000388098700011

Liver transplantation in a patient with hereditary haemorrhagic telangiectasia and pulmonary hypertension

FullText URL	fulltext.pdf
Author	Ejiri Kentaro\| Akagi, Satoshi\| Nakamura, Kazufumi\| Amioka, Naofumi\| Ichikawa, Keishi\| Yagi, Takahito\| Ito, Hiroshi\|
Keywords	Rendu-Osler-Weber syndrome arteriovenous malformation pulmonary haemorrhage
Published Date	2019-12-18
Publication Title	Pulmonary Circulation
Volume	volume9
Issue	issue4
Publisher	SAGE Publications Inc
ISSN	2045-8932
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2019.
File Version	publisher
PubMed ID	31903186
DOI	10.1177/2045894019896677
Web of Science KeyUT	000503484500001
Related Url	isVersionOf https://doi.org/10.1177/2045894019896677

Current Treatment Strategies and Nanoparticle-Mediated Drug Delivery Systems for Pulmonary Arterial Hypertension

FullText URL	fulltext.pdf
Author	Nakamura, Kazufumi\| Akagi, Satoshi\| Ejiri, Kentaro\| Yoshida, Masashi\| Miyoshi, Toru\| Toh, Norihisa\| Nakagawa, Koji\| Takaya, Yoichi\| Matsubara, Hiromi\| Ito, Hiroshi\|
Keywords	pulmonary arterial hypertension prostaglandin I-2 nitric oxide endothelin
Published Date	2019-11-23
Publication Title	International Journal of Molecular Sciences
Volume	volume20
Issue	issue23
Publisher	MDPI
Start Page	5885
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 by the authors.
File Version	publisher
PubMed ID	31771203
DOI	10.3390/ijms20235885
Web of Science KeyUT	000504428300067
Related Url	isVersionOf https://doi.org/10.3390/ijms20235885

Deficiency of CD44 prevents thoracic aortic dissection in a murine model

FullText URL	fulltext.pdf
Author	Hatipoglu, Omer F.\| Miyoshi, Toru\| Yonezawa, Tomoko\| Kondo, Megumi\| Amioka, Naofumi\| Yoshida, Masashi\| Akagi, Satoshi\| Nakamura, Kazufumi\| Hirohata, Satoshi\| Ito, Hiroshi\|
Keywords	Aneurysm Aortic diseases
Published Date	2020-04-22
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature
Start Page	6869
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	32321956
DOI	10.1038/s41598-020-63824-9
Web of Science KeyUT	000560329100004
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-63824-9

Effect of Luseogliflozin on Heart Failure With Preserved Ejection Fraction in Patients With Diabetes Mellitus

FullText URL	fulltext.pdf
Author	Ejiri, Kentaro\| Miyoshi, Toru\| Kihara, Hajime\| Hata, Yoshiki\| Nagano, Toshihiko\| Takaishi, Atsushi\| Toda, Hironobu\| Nanba, Seiji\| Nakamura, Yoichi\| Akagi, Satoshi\| Sakuragi, Satoru\| Minagawa, Taro\| Kawai, Yusuke\| Nishii, Nobuhiro\| Fuke, Soichiro\| Yoshikawa, Masaki\| Nakamura, Kazufumi\| Ito, Hiroshi\|
Keywords	B-type natriuretic peptide diabetes mellitus heart failure sodium-glucose cotransporter 2 inhibitor
Published Date	2020-08-18
Publication Title	Journal of the American Heart association
Volume	volume9
Issue	issue16
Publisher	Wiley
Start Page	e015103
ISSN	2047-9980
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Authors.
File Version	publisher
PubMed ID	32805185
DOI	10.1161/JAHA.119.015103
Web of Science KeyUT	000574868200036
Related Url	isVersionOf https://doi.org/10.1161/JAHA.119.015103

Marked Reduction of Pulmonary Artery Pressure After Registration for Lung Transplantation Is Associated With Long-Term Survival in Patients With Pulmonary Arterial Hypertension　― Cohort Study ―

FullText URL	fulltext.pdf
Author	Akagi, Satoshi\| Matsubara, Hiromi\| Nakamura, Kazufumi\| Oto, Takahiro\| Ejiri, Kentaro\| Ito, Hiroshi\|
Keywords	Lung transplantation Pulmonary artery hypertension Pulmonary artery pressure Survival
Published Date	2020-01-24
Publication Title	Circulation Journal
Volume	volume84
Issue	issue2
Publisher	The Japanese Circulation Society
Start Page	245
End Page	251
ISSN	1346-9843
NCID	AA11591968
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	publisher
DOI	10.1253/circj.CJ-19-0784
Related Url	isVersionOf https://doi.org/10.1253/circj.CJ-19-0784

Improvement of lung function and pulmonary hypertension after pulmonary aneurysm repair: case series

FullText URL	fulltext.pdf
Author	Akagi, Satoshi\| Ejiri, Kentaro\| Kasahara, Shingo\| Nakamura, Kazufumi\| Ito, Hiroshi\|
Keywords	vital capacity pulmonary artery pressure lung perfusion and oxygenation
Published Date	2019-02-15
Publication Title	Pulmonary Circulation
Volume	volume9
Issue	issue1
Publisher	SAGE Publications
Start Page	2045894019831217
ISSN	2045-8932
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s). 2019
File Version	publisher
PubMed ID	30698485
DOI	10.1177/2045894019831217
Web of Science KeyUT	000458818800001
Related Url	isVesionOf https://doi.org/10.1177/2045894019831217

Inhibitory effects of RAGE-aptamer on development of monocrotaline-induced pulmonary arterial hypertension in rats

FullText URL	fulltext20210630-1.pdf
Author	Nakamura, Kazufumi\| Akagi, Satoshi\| Ejiri, Kentaro\| Yoshida, Masashi\| Miyoshi, Toru\| Sakaguchi, Masakiyo\| Amioka, Naofumi\| Suastika, Luh Oliva Saraswati\| Kondo, Megumi\| Nakayama, Rie\| Takaya, Yoichi\| Higashimoto, Yuichiro\| Fukami, Kei\| Matsubara, Hiromi\| Ito, Hiroshi\|
Keywords	pulmonary artery smooth muscle cells RAGE aptamer
Note	This is an Accepted Manuscript published by Elsevier. ©2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/\|
Published Date	2020-12-30
Publication Title	Journal of Cardiology
Volume	volume78
Issue	issue1
Publisher	Elsevier
Start Page	12
End Page	16
ISSN	09145087
NCID	AN10070473
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
File Version	author
PubMed ID	33386219
DOI	10.1016/j.jjcc.2020.12.009
Web of Science KeyUT	000661421700002
Related Url	isVersionOf https://doi.org/10.1016/j.jjcc.2020.12.009

A case of a middle-aged patient with a ventricular septal defect complicated by severe pulmonary hypertension-stepwise surgical repair with pulmonary vasodilators-

FullText URL	fulltext20210519_3.pdf
Author	Kanai, Anna\| Koitabashi, Norimichi\| Akagi, Satoshi\| Sorimachi, Hidemi\| Ishibashi, Yohei\| Nagasaka, Takashi\| Takama, Noriaki\| Soma, Katsura\| Yao, Atsushi\| Kasahara, Shingo\| Kurabayashi, Masahiko\|
Keywords	Pulmonary arterial hypertension Ventricular septal defect Treat-and-repair strategy
Published Date	2021-03-09
Publication Title	Journal of Cardiology Cases
Publisher	Elsevier
ISSN	18785409
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Japanese College of Cardiology.
File Version	publisher
DOI	10.1016/j.jccase.2021.02.013
Related Url	isVersionOf https://doi.org/10.1016/j.jccase.2021.02.013

Efficacy of shear wave elastography for evaluating right ventricular myocardial fibrosis in monocrotaline-induced pulmonary hypertension rats

FullText URL	fulltext20210629-2.pdf
Author	Nakayama, Rie\| Takaya, Yoichi\| Nakamura, Kazufumi\| Kondo, Megumi\| Kobayashi, Kaoru\| Ohno, Yuko\| Amioka, Naofumi\| Akagi, Satoshi\| Yoshida, Masashi\| Miyoshi, Toru\| Ito, Hiroshi\|
Keywords	Dispersion Elasticity Myocardium Right ventricular function Shear wave elastography
Note	This is an Accepted Manuscript of an article published by Elsevier. © 2021 Japanese College of Cardiology. Published by Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jjcc.2021.01.015] .\|
Published Date	2021-02-07
Publication Title	Journal of Cardiology
Volume	volume78
Issue	issue1
Publisher	Elsevier
Start Page	17
End Page	23
ISSN	0914-5087
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
File Version	author
PubMed ID	33568315
DOI	10.1016/j.jjcc.2021.01.015
Web of Science KeyUT	000661421700003
Related Url	isVersionOf https://doi.org/10.1016/j.jjcc.2021.01.015

Effects of luseogliflozin on estimated plasma volume in patients with heart failure with preserved ejection fraction

FullText URL	fulltext.pdf
Author	Nakashima, Mitsutaka\| Miyoshi, Toru\| Ejiri, Kentaro\| Kihara, Hajime\| Hata, Yoshiki\| Nagano, Toshihiko\| Takaishi, Atsushi\| Toda, Hironobu\| Nanba, Seiji\| Nakamura, Yoichi\| Akagi, Satoshi\| Sakuragi, Satoru\| Minagawa, Taro\| Kawai, Yusuke\| Nishii, Nobuhiro\| Fuke, Soichiro\| Yoshikawa, Masaki\| Nakamura, Kazufumi\| Ito, Hiroshi\| MUSCAT-HF Study Investigators\|
Keywords	Estimated plasma volume Heart failure with preserved ejection fraction Luseogliflozin Sodium glucose co-transporter 2 inhibitors Voglibose
Published Date	2021-11-03
Publication Title	Esc Heart Failure
Publisher	Wiley Periodicals, Inc
ISSN	2055-5822
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Authors.
File Version	publisher
DOI	10.1002/ehf2.13683
Web of Science KeyUT	000714002000001
Related Url	isVersionOf https://doi.org/10.1002/ehf2.13683

Efficacy of shear wave elasticity for evaluating myocardial hypertrophy in hypertensive rats

FullText URL	fulltext.pdf
Author	Takaya, Yoichi\| Nakamura, Kazufumi\| Nakayama, Rie\| Ohtsuka, Hiroaki\| Amioka, Naofumi\| Kondo, Megumi\| Akazawa, Kaoru\| Ohno, Yuko\| Ichikawa, Keishi\| Saito, Yukihiro\| Akagi, Satoshi\| Yoshida, Masashi\| Miyoshi, Toru\| Ito, Hiroshi\|
Published Date	2021-11-24
Publication Title	Scientific Reports
Volume	volume11
Issue	issue1
Publisher	Nature Portfolio
Start Page	22812
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021
File Version	publisher
PubMed ID	34819579
DOI	10.1038/s41598-021-02271-6
Web of Science KeyUT	000722365800023
Related Url	isVersionOf https://doi.org/10.1038/s41598-021-02271-6

Fragmented QRS as a predictor of cardiac events in patients with cardiac sarcoidosis

FullText URL	fulltext20220412-1.pdf
Author	Ogura, Soichiro\| Nakamura, Kazufumi\| Morita, Hiroshi\| Nakagawa, Koji\| Nishii, Nobuhiro\| Akagi, Satoshi\| Toh, Norihisa\| Takaya, Yoichi\| Yoshida, Masashi\| Miyoshi, Toru\| Watanabe, Atsuyuki\| Ito, Hiroshi\|
Note	© 2021 Japanese College of Cardiology. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.jjcc.2021.10.022 . \|
Published Date	2022-3
Publication Title	Journal of Cardiology
Volume	volume79
Issue	issue3
Publisher	Elsevier BV
Start Page	446
End Page	452
ISSN	0914-5087
NCID	AN10070473
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Japanese College of Cardiology
File Version	author
PubMed ID	34799215
DOI	10.1016/j.jjcc.2021.10.022
Web of Science KeyUT	000768146000018
Related Url	isVersionOf https://doi.org/10.1016/j.jjcc.2021.10.022

Pathophysiology and Treatment of Diabetic Cardiomyopathy and Heart Failure in Patients with Diabetes Mellitus

FullText URL	fulltext.pdf
Author	Nakamura, Kazufumi\| Miyoshi, Toru\| Yoshida, Masashi\| Akagi, Satoshi\| Saito, Yukihiro\| Ejiri, Kentaro\| Matsuo, Naoaki\| Ichikawa, Keishi\| Iwasaki, Keiichiro\| Naito, Takanori\| Namba, Yusuke\| Yoshida, Masatoki\| Sugiyama, Hiroki\| Ito, Hiroshi\|
Keywords	heart failure lipotoxicity SGLT2 inhibitor
Published Date	2022-03-25
Publication Title	International Journal Of Molecular Sciences
Volume	volume23
Issue	issue7
Publisher	MDPI
Start Page	3587
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 by the authors.
File Version	publisher
PubMed ID	35408946
DOI	10.3390/ijms23073587
Web of Science KeyUT	000780514100001
Related Url	isVersionOf https://doi.org/10.3390/ijms23073587

Enhancement of pacing function by HCN4 overexpression in human pluripotent stem cell-derived cardiomyocytes

FullText URL	fulltext.pdf
Author	Saito, Yukihiro\| Nakamura, Kazufumi\| Yoshida, Masashi\| Sugiyama, Hiroki\| Akagi, Satoshi\| Miyoshi, Toru\| Morita, Hiroshi\| Ito, Hiroshi\|
Keywords	Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4 Human induced pluripotent stem cell-derived cardiomyocytes Pacing
Published Date	2022-04-01
Publication Title	STEM Cell Research & Therapy
Volume	volume13
Issue	issue1
Publisher	BMC
Start Page	141
ISSN	1757-6512
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2022.
File Version	publisher
PubMed ID	35365232
DOI	10.1186/s13287-022-02818-y
Web of Science KeyUT	000778298400007
Related Url	isVersionOf https://doi.org/10.1186/s13287-022-02818-y

LCZ696 ameliorates doxorubicin-induced cardiomyocyte toxicity in rats

FullText URL	fulltext.pdf
Author	Miyoshi, Toru\| Nakamura, Kazufumi\| Amioka, Naofumi\| Hatipoglu, Omer F.\| Yonezawa, Tomoko\| Saito, Yukihiro\| Yoshida, Masashi\| Akagi, Satoshi\| Ito, Hiroshi\|
Published Date	2022-03-23
Publication Title	Scientific Reports
Volume	volume12
Issue	issue1
Publisher	Nature Portfolio
Start Page	4930
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2022
File Version	publisher
PubMed ID	35322164
DOI	10.1038/s41598-022-09094-z
Web of Science KeyUT	000772605500054
Related Url	isVersionOf https://doi.org/10.1038/s41598-022-09094-z

Impact of shear wave dispersion slope analysis for assessing the severity of myocarditis

FullText URL	fulltext.pdf
Author	Amioka, Naofumi\| Takaya, Yoichi\| Nakamura, Kazufumi\| Kondo, Megumi\| Akazawa, Kaoru\| Ohno, Yuko\| Ichikawa, Keishi\| Nakayama, Rie\| Saito, Yukihiro\| Akagi, Satoshi\| Miyoshi, Toru\| Yoshida, Masashi\| Morita, Hiroshi\| Ito, Hiroshi\|
Published Date	2022-05-24
Publication Title	Scientific Reports
Volume	volume12
Issue	issue1
Publisher	Nature Portfolio
Start Page	8776
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2022
File Version	publisher
PubMed ID	35610503
DOI	10.1038/s41598-022-12935-6
Web of Science KeyUT	000799975800070
Related Url	isVersionOf https://doi.org/10.1038/s41598-022-12935-6

Quantification of Lung Perfusion Blood Volume in Dual-Energy Computed Tomography in Patients with Pulmonary Hypertension

FullText URL	fulltext.pdf
Author	Ugawa, Satoko\| Akagi, Satoshi\| Ejiri, Kentaro\| Nakamura, Kazufumi\| Ito, Hiroshi\|
Keywords	pulmonary vascular bed pulmonary arterial hypertension lung perfusion scintigraphy
Published Date	2022-05-05
Publication Title	Life-Basel
Volume	volume12
Issue	issue5
Publisher	MDPI
Start Page	684
ISSN	2075-1729
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 by the authors.
File Version	publisher
PubMed ID	35629352
DOI	10.3390/life12050684
Web of Science KeyUT	000801579500001
Related Url	isVersionOf https://doi.org/10.3390/life12050684