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Author Miyoshi, Toru| Nakamura, Kazufumi| Amioka, Naofumi| Hatipoglu, Omer F.| Yonezawa, Tomoko| Saito, Yukihiro| Yoshida, Masashi| Akagi, Satoshi| Ito, Hiroshi|
Published Date 2022-03-23
Publication Title Scientific Reports
Volume volume12
Issue issue1
Publisher Nature Portfolio
Start Page 4930
ISSN 2045-2322
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
PubMed ID 35322164
DOI 10.1038/s41598-022-09094-z
Web of Science KeyUT 000772605500054
Related Url isVersionOf https://doi.org/10.1038/s41598-022-09094-z
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Author Saito, Yukihiro| Nakamura, Kazufumi| Yoshida, Masashi| Sugiyama, Hiroki| Akagi, Satoshi| Miyoshi, Toru| Morita, Hiroshi| Ito, Hiroshi|
Keywords Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4 Human induced pluripotent stem cell-derived cardiomyocytes Pacing
Published Date 2022-04-01
Publication Title STEM Cell Research & Therapy
Volume volume13
Issue issue1
Publisher BMC
Start Page 141
ISSN 1757-6512
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 35365232
DOI 10.1186/s13287-022-02818-y
Web of Science KeyUT 000778298400007
Related Url isVersionOf https://doi.org/10.1186/s13287-022-02818-y
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Author Nakamura, Kazufumi| Miyoshi, Toru| Yoshida, Masashi| Akagi, Satoshi| Saito, Yukihiro| Ejiri, Kentaro| Matsuo, Naoaki| Ichikawa, Keishi| Iwasaki, Keiichiro| Naito, Takanori| Namba, Yusuke| Yoshida, Masatoki| Sugiyama, Hiroki| Ito, Hiroshi|
Keywords heart failure lipotoxicity SGLT2 inhibitor
Published Date 2022-03-25
Publication Title International Journal Of Molecular Sciences
Volume volume23
Issue issue7
Publisher MDPI
Start Page 3587
ISSN 1422-0067
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 35408946
DOI 10.3390/ijms23073587
Web of Science KeyUT 000780514100001
Related Url isVersionOf https://doi.org/10.3390/ijms23073587
Author Ogura, Soichiro| Nakamura, Kazufumi| Morita, Hiroshi| Nakagawa, Koji| Nishii, Nobuhiro| Akagi, Satoshi| Toh, Norihisa| Takaya, Yoichi| Yoshida, Masashi| Miyoshi, Toru| Watanabe, Atsuyuki| Ito, Hiroshi|
Note © 2021 Japanese College of Cardiology. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.jjcc.2021.10.022 . |
Published Date 2022-3
Publication Title Journal of Cardiology
Volume volume79
Issue issue3
Publisher Elsevier BV
Start Page 446
End Page 452
ISSN 0914-5087
NCID AN10070473
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Japanese College of Cardiology
File Version author
PubMed ID 34799215
DOI 10.1016/j.jjcc.2021.10.022
Web of Science KeyUT 000768146000018
Related Url isVersionOf https://doi.org/10.1016/j.jjcc.2021.10.022
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Author Takaya, Yoichi| Nakamura, Kazufumi| Nakayama, Rie| Ohtsuka, Hiroaki| Amioka, Naofumi| Kondo, Megumi| Akazawa, Kaoru| Ohno, Yuko| Ichikawa, Keishi| Saito, Yukihiro| Akagi, Satoshi| Yoshida, Masashi| Miyoshi, Toru| Ito, Hiroshi|
Published Date 2021-11-24
Publication Title Scientific Reports
Volume volume11
Issue issue1
Publisher Nature Portfolio
Start Page 22812
ISSN 2045-2322
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021
File Version publisher
PubMed ID 34819579
DOI 10.1038/s41598-021-02271-6
Web of Science KeyUT 000722365800023
Related Url isVersionOf https://doi.org/10.1038/s41598-021-02271-6
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Author Nakashima, Mitsutaka| Miyoshi, Toru| Ejiri, Kentaro| Kihara, Hajime| Hata, Yoshiki| Nagano, Toshihiko| Takaishi, Atsushi| Toda, Hironobu| Nanba, Seiji| Nakamura, Yoichi| Akagi, Satoshi| Sakuragi, Satoru| Minagawa, Taro| Kawai, Yusuke| Nishii, Nobuhiro| Fuke, Soichiro| Yoshikawa, Masaki| Nakamura, Kazufumi| Ito, Hiroshi| MUSCAT-HF Study Investigators|
Keywords Estimated plasma volume Heart failure with preserved ejection fraction Luseogliflozin Sodium glucose co-transporter 2 inhibitors Voglibose
Published Date 2021-11-03
Publication Title Esc Heart Failure
Publisher Wiley Periodicals, Inc
ISSN 2055-5822
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Authors.
File Version publisher
DOI 10.1002/ehf2.13683
Web of Science KeyUT 000714002000001
Related Url isVersionOf https://doi.org/10.1002/ehf2.13683
FullText URL fulltext20210629-2.pdf
Author Nakayama, Rie| Takaya, Yoichi| Nakamura, Kazufumi| Kondo, Megumi| Kobayashi, Kaoru| Ohno, Yuko| Amioka, Naofumi| Akagi, Satoshi| Yoshida, Masashi| Miyoshi, Toru| Ito, Hiroshi|
Keywords Dispersion Elasticity Myocardium Right ventricular function Shear wave elastography
Note This is an Accepted Manuscript of an article published by Elsevier.<br> © 2021 Japanese College of Cardiology. Published by Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jjcc.2021.01.015] .|
Published Date 2021-02-07
Publication Title Journal of Cardiology
Volume volume78
Issue issue1
Publisher Elsevier
Start Page 17
End Page 23
ISSN 0914-5087
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
File Version author
PubMed ID 33568315
DOI 10.1016/j.jjcc.2021.01.015
Web of Science KeyUT 000661421700003
Related Url isVersionOf https://doi.org/10.1016/j.jjcc.2021.01.015
FullText URL fulltext20210519_3.pdf
Author Kanai, Anna| Koitabashi, Norimichi| Akagi, Satoshi| Sorimachi, Hidemi| Ishibashi, Yohei| Nagasaka, Takashi| Takama, Noriaki| Soma, Katsura| Yao, Atsushi| Kasahara, Shingo| Kurabayashi, Masahiko|
Keywords Pulmonary arterial hypertension Ventricular septal defect Treat-and-repair strategy
Published Date 2021-03-09
Publication Title Journal of Cardiology Cases
Publisher Elsevier
ISSN 18785409
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Japanese College of Cardiology.
File Version publisher
DOI 10.1016/j.jccase.2021.02.013
Related Url isVersionOf https://doi.org/10.1016/j.jccase.2021.02.013
FullText URL fulltext20210630-1.pdf
Author Nakamura, Kazufumi| Akagi, Satoshi| Ejiri, Kentaro| Yoshida, Masashi| Miyoshi, Toru| Sakaguchi, Masakiyo| Amioka, Naofumi| Suastika, Luh Oliva Saraswati| Kondo, Megumi| Nakayama, Rie| Takaya, Yoichi| Higashimoto, Yuichiro| Fukami, Kei| Matsubara, Hiromi| Ito, Hiroshi|
Keywords pulmonary artery smooth muscle cells RAGE aptamer
Note This is an Accepted Manuscript published by Elsevier.<br> ©2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/|
Published Date 2020-12-30
Publication Title Journal of Cardiology
Volume volume78
Issue issue1
Publisher Elsevier
Start Page 12
End Page 16
ISSN 09145087
NCID AN10070473
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
File Version author
PubMed ID 33386219
DOI 10.1016/j.jjcc.2020.12.009
Web of Science KeyUT 000661421700002
Related Url isVersionOf https://doi.org/10.1016/j.jjcc.2020.12.009
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Author Akagi, Satoshi| Ejiri, Kentaro| Kasahara, Shingo| Nakamura, Kazufumi| Ito, Hiroshi|
Keywords vital capacity pulmonary artery pressure lung perfusion and oxygenation
Published Date 2019-02-15
Publication Title Pulmonary Circulation
Volume volume9
Issue issue1
Publisher SAGE Publications
Start Page 2045894019831217
ISSN 2045-8932
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2019
File Version publisher
PubMed ID 30698485
DOI 10.1177/2045894019831217
Web of Science KeyUT 000458818800001
Related Url isVesionOf https://doi.org/10.1177/2045894019831217
FullText URL fulltext.pdf
Author Akagi, Satoshi| Matsubara, Hiromi| Nakamura, Kazufumi| Oto, Takahiro| Ejiri, Kentaro| Ito, Hiroshi|
Keywords Lung transplantation Pulmonary artery hypertension Pulmonary artery pressure Survival
Published Date 2020-01-24
Publication Title Circulation Journal
Volume volume84
Issue issue2
Publisher The Japanese Circulation Society
Start Page 245
End Page 251
ISSN 1346-9843
NCID AA11591968
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version publisher
DOI 10.1253/circj.CJ-19-0784
Related Url isVersionOf https://doi.org/10.1253/circj.CJ-19-0784
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Author Ejiri, Kentaro| Miyoshi, Toru| Kihara, Hajime| Hata, Yoshiki| Nagano, Toshihiko| Takaishi, Atsushi| Toda, Hironobu| Nanba, Seiji| Nakamura, Yoichi| Akagi, Satoshi| Sakuragi, Satoru| Minagawa, Taro| Kawai, Yusuke| Nishii, Nobuhiro| Fuke, Soichiro| Yoshikawa, Masaki| Nakamura, Kazufumi| Ito, Hiroshi|
Keywords B-type natriuretic peptide diabetes mellitus heart failure sodium-glucose cotransporter 2 inhibitor
Published Date 2020-08-18
Publication Title Journal of the American Heart association
Volume volume9
Issue issue16
Publisher Wiley
Start Page e015103
ISSN 2047-9980
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
PubMed ID 32805185
DOI 10.1161/JAHA.119.015103
Web of Science KeyUT 000574868200036
Related Url isVersionOf https://doi.org/10.1161/JAHA.119.015103
FullText URL fulltext.pdf
Author Hatipoglu, Omer F.| Miyoshi, Toru| Yonezawa, Tomoko| Kondo, Megumi| Amioka, Naofumi| Yoshida, Masashi| Akagi, Satoshi| Nakamura, Kazufumi| Hirohata, Satoshi| Ito, Hiroshi|
Keywords Aneurysm Aortic diseases
Published Date 2020-04-22
Publication Title Scientific Reports
Volume volume10
Issue issue1
Publisher Nature
Start Page 6869
ISSN 2045-2322
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2020
File Version publisher
PubMed ID 32321956
DOI 10.1038/s41598-020-63824-9
Web of Science KeyUT 000560329100004
Related Url isVersionOf https://doi.org/10.1038/s41598-020-63824-9
FullText URL fulltext.pdf
Author Nakamura, Kazufumi| Akagi, Satoshi| Ejiri, Kentaro| Yoshida, Masashi| Miyoshi, Toru| Toh, Norihisa| Nakagawa, Koji| Takaya, Yoichi| Matsubara, Hiromi| Ito, Hiroshi|
Keywords pulmonary arterial hypertension prostaglandin I-2 nitric oxide endothelin
Published Date 2019-11-23
Publication Title International Journal of Molecular Sciences
Volume volume20
Issue issue23
Publisher MDPI
Start Page 5885
ISSN 1422-0067
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2019 by the authors.
File Version publisher
PubMed ID 31771203
DOI 10.3390/ijms20235885
Web of Science KeyUT 000504428300067
Related Url isVersionOf https://doi.org/10.3390/ijms20235885
FullText URL fulltext.pdf
Author Ejiri Kentaro| Akagi, Satoshi| Nakamura, Kazufumi| Amioka, Naofumi| Ichikawa, Keishi| Yagi, Takahito| Ito, Hiroshi|
Keywords Rendu-Osler-Weber syndrome arteriovenous malformation pulmonary haemorrhage
Published Date 2019-12-18
Publication Title Pulmonary Circulation
Volume volume9
Issue issue4
Publisher SAGE Publications Inc
ISSN 2045-8932
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2019.
File Version publisher
PubMed ID 31903186
DOI 10.1177/2045894019896677
Web of Science KeyUT 000503484500001
Related Url isVersionOf https://doi.org/10.1177/2045894019896677
JaLCDOI 10.18926/AMO/54600
FullText URL 70_5_397.pdf
Author Akagi, Satoshi| Nakamura, Kazufumi| Akagi, Teiji| Nakagawa, Koji| Takaya, Yoichi| Sarashina, Toshihiro| Ejiri, Kentaro| Ito, Hiroshi|
Abstract A treatment strategy for patients with pulmonary hypertension (PH) and atrial septal defect (ASD) remains unclear. This study was designed to evaluate the effects of initial repair of ASD followed by treatment with PH-specific drugs in patients with PH and ASD. Eligible patients receive transcatheter ASD closure followed by treatment with bosentan and sildenafil. Right heart catheterization is performed at baseline and at 12, 24 and 48 weeks. The primary endpoint is change in pulmonary artery pressure and pulmonary vascular resistance from baseline to follow-up. This study should provide valuable information to establish a therapeutic strategy for PH and ASD.
Keywords pulmonary hypertension atrial septal defect repair and treat transcatheter closure
Amo Type Clinical Study Protocols
Publication Title Acta Medica Okayama
Published Date 2016-10
Volume volume70
Issue issue5
Publisher Okayama University Medical School
Start Page 397
End Page 400
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 27777434
Web of Science KeyUT 000388098700011
JaLCDOI 10.18926/AMO/53519
FullText URL 69_3_129.pdf
Author Akagi, Satoshi| Nakamura, Kazufumi| Matsubara, Hiromi| Ogawa, Aiko| Sarashina, Toshihiro| Ejiri, Kentaro| Ito, Hiroshi|
Abstract Pulmonary arterial hypertension (PAH) is characterized by elevation of pulmonary artery pressure caused by pulmonary vasoconstriction and vascular remodeling, which leads to right heart failure and death. Epoprostenol (prostaglandin I2) has a potent short-acting vasodilator property, and intravenous continuous epoprostenol is therefore used for treatment of PAH. Here we review evidence for the usefulness of intravenous continuous epoprostenol therapy in patients with PAH. Epoprostenol therapy is effective in idiopathic PAH patients and in patients with PAH associated with connective tissue disease, portal hypertension or congenital heart diseases, but it is not effective in patients with pulmonary veno-occlusive disease or pulmonary capillary hemangiomatosis. High-dose epoprostenol therapy markedly improved hemodynamics in some patients with PAH, possibly due to reverse remodeling of pulmonary arteries. This therapy has several side effects and complications such as headache, hypotension and catheter-related infections. Intravenous continuous epoprostenol is an effective treatment, but there are still some problems to be resolved.
Keywords pulmonary arterial hypertension epoprostenol high-dose complications side effects
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2015-06
Volume volume69
Issue issue3
Publisher Okayama University Medical School
Start Page 129
End Page 136
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2015 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 26101188
Web of Science KeyUT 000356903000001
Title Alternative The 2013 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2013 Sunada Prize)
FullText URL 126_195.pdf
Author Akagi, Satoshi|
Abstract 受賞対象論文: Akagi S, Nakamura K, Matsubara H, Kusano KF, Kataoka N, Oto T, Miyaji K, Miura A, Ogawa A, Yoshida M, Ueda-Ishibashi H, Yutani C, Ito H:Prostaglandin I2 induces apoptosis via upregulation of Fas ligand in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. Int J Cardiol (2013) 165, 499-505.
Publication Title 岡山医学会雑誌
Published Date 2014-12-01
Volume volume126
Issue issue3
Start Page 195
End Page 197
ISSN 0030-1558
language 日本語
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.195
NAID 130004903242