| Author | 松川 昭博| |
|---|---|
| Published Date | 2006-09-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume118 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Mominoki, Katsumi| Takashima, Rumi| Matsukawa, Akihiro| |
|---|---|
| Published Date | 2011-05 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume27 |
| Content Type | Article |
| Author | Yashiro, Masato| Tsukahara, Hirokazu| Matsukawa, Akihiro| Yamada, Mutsuko| Fujii, Yosuke| Nagaoka, Yoshiharu| Tsuge, Mitsuru| Yamashita, Nobuko| Ito, Toshihiro| Yamada, Masao| Masutani, Hiroshi| Yodoi, Junji| Morishima, Tsuneo| |
|---|---|
| Published Date | 2013-08-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume125 |
| Issue | issue2 |
| Content Type | Journal Article |
| FullText URL | fulltext.pdf Figures.pdf Tables_Figure_legends.pdf |
|---|---|
| Author | Uchino, Kaori| Notohara, Kenji| Uehara, Takeshi| Kuraishi, Yasuhiro| Itakura, Junya| Matsukawa, Akihiro| |
| Keywords | biopsy feasibility studies gastric mucosa gastritis IgG4 IgG4‐related disease immunoglobulin G4 immunohistochemistry plasma cells |
| Note | This is the peer reviewed version of the following article: Kaori Uchino et. al. Utility of gastric biopsy in diagnosing IgG4‐related gastrointestinal disease. Pathology International (2020), which has been published in final form at [https://doi.org/10.1111/pin.13059. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This fulltext is available in Jan. 2022.| |
| Published Date | 2020-12-30 |
| Publication Title | Pathology International |
| Volume | volume71 |
| Issue | issue2 |
| Publisher | Wiley |
| Start Page | 124 |
| End Page | 134 |
| ISSN | 1320-5463 |
| NCID | AA10984364 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 33378576 |
| DOI | 10.1111/pin.13059 |
| Web of Science KeyUT | 000603493000001 |
| Related Url | isVersionOf https://doi.org/10.1111/pin.13059 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Miyahara, Hiroyuki| Hasegawa, Kosei| Yashiro, Masato| Ohara, Toshiaki| Fujisawa, Masayoshi| Yoshimura, Teizo| Matsukawa, Akihiro| Tsukahara, Hirokazu| |
| Published Date | 2022-03-21 |
| Publication Title | Scientific Reports |
| Volume | volume12 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 4819 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 35314758 |
| DOI | 10.1038/s41598-022-08791-z |
| Web of Science KeyUT | 000771589000002 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-022-08791-z |
| FullText URL | JGastroenterol_54_11_1019.pdf Table.pdf Figure 1.jpg Figure 2.jpg Figure 3A.tif Figure 3B.tif supplemental figure 1.jpg |
|---|---|
| Author | Matsumoto, Kazuyuki| Ohara, Toshiaki| Fujisawa, Masayoshi| Takaki, Akinobu| Takahara, Masahiro| Tanaka, Noriyuki| Kato, Hironari| Horiguchi, Shigeru| Yoshida, Ryuichi| Umeda, Yuzo| Fushimi, Soichiro| Yagi, Takahito| Matsukawa, Akihiro| Okada, Hiroyuki| |
| Keywords | Immunohistochemistry PD-L1 Pancreatic cancer |
| Note | This fulltext will be available in Apr 2020| |
| Published Date | 2019-04-29 |
| Publication Title | Journal of Gastroenterology |
| Volume | volume54 |
| Issue | issue11 |
| Start Page | 1019 |
| End Page | 1028 |
| ISSN | 09441174 |
| NCID | AA10988015 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31032528 |
| DOI | 10.1007/s00535-019-01586-6 |
| Web of Science KeyUT | 000492169400008 |
| Related Url | isVersionOf https://doi.org/10.1007/s00535-019-01586-6 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kawara, Akina| Mizuta, Ryo| Fujisawa, Masayoshi| Ito, Toshihiro| Li, Chunning| Nakamura, Kaoru| Sun, Cuiming| Kuwabara, Masaki| Kitabatake, Masahiro| Yoshimura, Teizo| Matsukawa, Akihiro| |
| Keywords | Cell signalling Mechanisms of disease |
| Published Date | 2020-10-05 |
| Publication Title | Scientific Reports |
| Volume | volume10 |
| Issue | issue1 |
| Publisher | Nature |
| Start Page | 16490 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2020 |
| File Version | publisher |
| PubMed ID | 33020583 |
| DOI | 10.1038/s41598-020-73752-3 |
| Web of Science KeyUT | 000577291800001 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-020-73752-3 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sun, Cuiming| Fujisawa, Masayoshi| Ohara, Toshiaki| Liu, Qiuying| Cao, Chen| Yang, Xu| Yoshimura, Teizo| Kunkel, Steven L.| Matsukawa, Akihiro| |
| Keywords | Liver damage MAPK Signal transduction and regulation Gene-modified mice Spred2 |
| Published Date | 2022-01 |
| Publication Title | Journal Of Advanced Research |
| Volume | volume35 |
| Publisher | Elsevier |
| Start Page | 71 |
| End Page | 86 |
| ISSN | 2090-1232 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 35003795 |
| DOI | 10.1016/j.jare.2021.03.014 |
| Web of Science KeyUT | 000736947300007 |
| Related Url | isVersionOf https://doi.org/10.1016/j.jare.2021.03.014 |
| FullText URL | FI_10_17.pdf |
|---|---|
| Author | Ohkura, Takahiro| Yoshimura, Teizo| Fujisawa, Masayoshi| Ohara, Toshiaki| Marutani, Rie| Usami, Kaya| Matsukawa, Akihiro| |
| Keywords | Ras/Raf/ERK/MAPK Spred2 adipocyte inflammation macrophage obesity |
| Published Date | 2019-01-22 |
| Publication Title | Frontiers in Immunology |
| Volume | volume10 |
| Publisher | Frontiers Media S.A |
| Start Page | 17 |
| ISSN | 1664-3224 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | Copyright © 2019 Authors |
| File Version | publisher |
| PubMed ID | 30723473 |
| DOI | 10.3389/fimmu.2019.00017 |
| Web of Science KeyUT | 000456196900002 |
| Related Url | isVersionOf https://doi.org/10.3389/fimmu.2019.00017 |
| Author | Wakabayashi, Hiroshi| Ito, Toshihiro| Fushimi, Soichiro| Nakashima, Yuki| Itakura, Jyunya| Liu, Qiuying| Win, Min Min| Sun, Cuiming| Chen, Cao| Sato, Miwa| Mino, Megumi| Ogino, Tetsuya| Makino, Hirofumi| Yoshimura, Akihiko| Matsukawa, Akihiro| |
|---|---|
| Published Date | 2012-09 |
| Publication Title | Clinical Immunology |
| Volume | volume144 |
| Issue | issue3 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/32897 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Matsukawa, Akihiro| |
| Abstract | The innate immune system provides immediate defense against infection and serves as the first line of host defense during infection. In innate immunity, leukocytes such as neutrophils and macrophages recognize and respond to pathogens in a non-specific manner. Therefore, the recruitment and activation of leukocytes are essential in innate immunity, and are governed by a variety of chemical mediators including cytokines. Cytokines are generally divided into 2 types, termed type-1 and type-2 cytokines. Type-1 cytokines are important in local host defense, while type-2 cytokines play a protective role when inflammatory response spreads to the body. These cytokines exert their biological functions through the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. STAT1/3/4/6 are transcription factors that mediate IFNgamma/IL-10/IL-12/IL-13 cytokine signaling, respectively. Evidence indicates that STAT proteins have a significant impact on innate immunity during sepsis. This review focuses on recent understandings in the regulation of innate immunity by STAT proteins during sepsis and septic shock. The suppressor of cytokine signaling (SOCS) proteins are a family of SH2 domain-containing cytoplasmic proteins that complete a negative feedback loop to attenuate signal transduction from cytokines that act through the JAK/STAT pathway. The participation of SOCS proteins in sepsis is also discussed. |
| Keywords | cytokines innate immunity sepsis SOCS STAT |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2007-10 |
| Volume | volume61 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 239 |
| End Page | 245 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 17971840 |
| Web of Science KeyUT | 000250431700001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Gao, Tong| Yang, Xu| Fujisawa, Masayoshi| Ohara, Toshiaki| Wang, Tianyi| Tomonobu, Nahoko| Sakaguchi, Masakiyo| Yoshimura, Teizo| Matsukawa, Akihiro| |
| Keywords | cancer stem cells epithelial-mesenchymal transition ERK1/2-MAPK tumorigenesis |
| Published Date | 2023-03-05 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume24 |
| Issue | issue5 |
| Publisher | MDPI |
| Start Page | 4996 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36902429 |
| DOI | 10.3390/ijms24054996 |
| Web of Science KeyUT | 000947675000001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms24054996 |
| JaLCDOI | 10.18926/AMO/66664 |
|---|---|
| FullText URL | 78_1_001.pdf |
| Author | Sun, Cuiming| Matsukawa, Akihiro| |
| Abstract | Liver fibrosis, which ultimately leads to liver cirrhosis and hepatocellular carcinoma, is a major health burden worldwide. The progression of liver fibrosis is the result of the wound-healing response of liver to repeated injury. Hepatic macrophages are cells with high heterogeneity and plasticity and include tissue-resident macrophages termed Kupffer cells, and recruited macrophages derived from circulating monocytes, spleen and peritoneal cavity. Studies have shown that hepatic macrophages play roles in the initiation and progression of liver fibrosis by releasing inflammatory cytokines/chemokines and pro-fibrogenic factors. Furthermore, the development of liver fibrosis has been shown to be reversible. Hepatic macrophages have been shown to alternately regulate both the regression and turnover of liver fibrosis by changing their phenotypes during the dynamic progression of liver fibrosis. In this review, we summarize the role of hepatic macrophages in the progression and regression of liver fibrosis. |
| Keywords | ERK-MAPK SPRED2 fibrosis macrophages |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-02 |
| Volume | volume78 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 1 |
| End Page | 8 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38419308 |
| Author | Yashiro, Masato| Tsukahara, Hirokazu| Matsukawa, Akihiro| Yamada, Mutsuko| Fujii, Yosuke| Nagaoka, Yoshiharu| Tsuge, Mitsuru| Yamashita, Nobuko| Ito, Toshihiro| Yamada, Masao| Masutani, Hiroshi| |
|---|---|
| Published Date | 2013-01 |
| Publication Title | Critical Care Medicine |
| Volume | volume41 |
| Issue | issue1 |
| Content Type | Journal Article |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hirano, Yutaka| Sugimoto, Seiichiro| Yamamoto, Sumiharu| Okada, Masanori| Otani, Shinji| Ohara, Toshiaki| Yamane, Masaomi| Matsukawa, Akihiro| Oto, Takahiro| Toyooka, Shinichi| |
| Keywords | Brain dead donor Donation after cardiac death Lung transplantation Organ preservation Rejection |
| Note | This is a post-peer-review, pre-copyedit version of an article published in General Thoracic and Cardiovascular Surgery. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11748-019-01181-9.| |
| Published Date | 2019-07-31 |
| Publication Title | General Thoracic and Cardiovascular Surgery |
| Volume | volume68 |
| Issue | issue1 |
| Publisher | Springer |
| Start Page | 57 |
| End Page | 62 |
| ISSN | 1863-6705 |
| NCID | AA12201344 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31367969 |
| DOI | 10.1007/s11748-019-01181-9 |
| Web of Science KeyUT | 000511499200009 |
| Related Url | isVersionOf https://doi.org/10.1007/s11748-019-01181-9 |
| FullText URL | fulltext20210824-3.pdf |
|---|---|
| Author | Yamaguchi, Takahiro| Yoshimura, Teizo| Ohara, Toshiaki| Fujisawa, Masayoshi| Tong, Gao| Matsukawa, Akihiro| |
| Keywords | Toll-like receptors cell migration metastasis epithelial mesenchymal transformation |
| Note | This is a post-peer-review, pre-copyedit version of an article published in Molecular Biology Reports. The final authenticated version is available online at: https://doi.org/10.1007/s11033-021-06625-1| |
| Published Date | 2021-8-14 |
| Publication Title | Molecular Biology Reports |
| Publisher | Springer Science and Business Media LLC |
| ISSN | 0301-4851 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 34390443 |
| DOI | 10.1007/s11033-021-06625-1 |
| Web of Science KeyUT | 000684897400002 |
| Related Url | isVersionOf https://doi.org/10.1007/s11033-021-06625-1 |
| JaLCDOI | 10.18926/AMO/51867 |
|---|---|
| FullText URL | 67_5_311.pdf |
| Author | Nishida, Keiichiro| Hashizume, Hiroyuki| Matsukawa, Akihiro| Hashizume, Kenzo| Shimamura, Yasunori| Torigoe, Yasuyuki| Ozaki, Toshifumi| |
| Abstract | We report a case of 4th metacarpal head collapse of a 19-year-old healthy man. MRI revealed T1 low and T2 high regions in the collapsed 4th metacarpal head, as well as in the right 3rd and left 4th metacarpal head. Our initial diagnosis was occult compression fracture due to avascular necrosis, known as Dieterich's disease. However, pathological findings of surgically resected right 4th metacarpal head were compatible with transient osteoporosis and metacarpal head fracture followed by active tissue repair. The autologous osteochondral transplants from costchondral junction survived and maintained their size and shape even at 10-year follow-up. |
| Keywords | occult compression fracture metacarpal head avascular necrosis osteochondral autograft |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-10 |
| Volume | volume67 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 311 |
| End Page | 317 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24145731 |
| Web of Science KeyUT | 000325836100005 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamane, Kentaro| Misawa, Haruo| Takigawa, Tomoyuki| Ito, Yoshihiro| Ozaki, Toshifumi| Matsukawa, Akihiro| |
| Keywords | hepatocyte growth factor spinal cord injury neural regeneration |
| Published Date | 2019-12-02 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume20 |
| Issue | issue23 |
| Publisher | MDPI |
| Start Page | 6078 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 by the authors. |
| File Version | publisher |
| PubMed ID | 31810304 |
| DOI | 10.3390/ijms20236078 |
| Web of Science KeyUT | 000504428300260 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms20236078 |
| Author | Yoshimura, Teizo| Howard, O. M. Zack| Ito, Toshihiro| Kuwabara, Masaki| Matsukawa, Akihiro| Chen, Keqiang| Liu, Ying| Liu, Mingyong| Oppenheim, Joost J.| Wang, Ji Ming| |
|---|---|
| Published Date | 2013-03-18 |
| Publication Title | PLOS ONE |
| Volume | volume8 |
| Issue | issue3 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/58275 |
|---|---|
| FullText URL | 74_2_159.pdf |
| Author | Thar Htet San| Ota, Yoko| Fushimi, Soichiro| Fujisawa, Masayoshi| Yanai, Hiroyuki| Toda, Hiroko| Kunitomo, Tadayoshi| Kodama, Keisuke| Matsukawa, Akihiro| |
| Abstract | Juvenile granulosa cell tumors (JGCTs) are rare ovarian tumors with overall good prognoses. They differ from adult granulosa cell tumors (AGCTs), which are well known for late recurrence. Most JGCTs (～97%) occur in individuals <30 years old. We report a recurrent JGCT in a 40-year-old woman 5 years after initial presentation. The histological appearance and lack of 402C>G missense point mutation of FOXL2 gene (characteristic of AGCT but absent in JGCT) allowed differentiation from AGCT. This is the first comprehensive report of JGCT with late recurrence. Although rare, late recurrence of JGCT can occur; long-term surveillance is suggested. |
| Keywords | juvenile granulosa cell tumor late recurrence adult granulosa cell tumor |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 159 |
| End Page | 163 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341591 |
| Web of Science KeyUT | 000528278500010 |
| NAID | 120006839454 |
