JaLCDOI | 10.18926/AMO/53556 |
---|---|
FullText URL | 69_4_205.pdf |
Author | Okada, Yoshiki| Endo, Hirosuke| Mitani, Shigeru| Fujiwara, Kazuo| Tetsunaga, Tomonori| Kagawa, Yohei| Fujii, Yosuke| Kunisada, Toshiyuki| Ozaki, Toshifumi| |
Abstract | Total hip arthroplasty (THA) is the most effective treatment for advanced or end-stage hip osteoarthritis. However, venous thromboembolism (VTE) remains one of its unresolved complications. We reviewed the records of 322 patients undergoing primary THA and investigated the efficacy of anticoagulant prophylaxis for VTE. Our study cohort consisted of 60 patients who received no anticoagulants, 100 patients who received a factor Xa inhibitor (fondaparinux), 100 patients who received low molecular weight heparin (enoxaparin), and 62 patients who selectively received no anticoagulant prophylaxis due to perioperative bleeding, weight, and/or hemoglobin concentration. Enhanced 64-slice multidetector row computed tomography was performed postoperatively for 7 days in all cases. The incidence of VTE in the four groups was 15オ, 9.0オ, 6.0オ, and 6.4オ, respectively. The incidence of VTE was significantly lower in the groups receiving anticoagulant prophylaxis and the group selectively receiving no anticoagulant prophylaxis than in the group receiving no anticoagulants. Complications of fondaparinux therapy included hepatic dysfunction in 4 cases (4.0オ), minor bleeding in 2 cases (2.0オ), persistent wound drainage in 3 cases (3.0オ), and eruption in 1 case (1.0オ). The complications of enoxaparin therapy were persistent wound drainage in 1 case (1.0オ) and progression of anemia in 1 case (1.0オ). The incidence of VTE was low in patients who selectively received no anticoagulant prophylaxis, so we conclude that anticoagulant prophylaxis should be used selectively in THA cases. |
Keywords | total hip arthroplasty venous thromboembolism anticoagulant prophylaxis complications |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2015-08 |
Volume | volume69 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 205 |
End Page | 212 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 26289911 |
Web of Science KeyUT | 000365519100003 |
Related Url | http://doi.org/10.18926/AMO/53680 |
JaLCDOI | 10.18926/AMO/53680 |
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FullText URL | 69_5_325.pdf |
Author | Okada, Yoshiki| Endo, Hirosuke| Mitani, Shigeru| Fujiwara, Kazuo| Tetsunaga, Tomonori| Kagawa, Yohei| Fujii, Yosuke| Kunisada, Toshiyuki| Ozaki, Toshifumi| |
Abstract | Total hip arthroplasty (THA) is the most effective treatment for advanced or end-stage hip osteoarthritis. However, venous thromboembolism (VTE) remains one of its unresolved complications. We reviewed the records of 322 patients undergoing primary THA and investigated the efficacy of anticoagulant prophylaxis for VTE. Our study cohort consisted of 60 patients who received no anticoagulants, 100 patients who received a factor Xa inhibitor (fondaparinux), 100 patients who received low molecular weight heparin (enoxaparin), and 62 patients who selectively received no anticoagulant prophylaxis due to perioperative bleeding, weight, and/or hemoglobin concentration. Enhanced 64-slice multidetector row computed tomography was performed postoperatively for 7 days in all cases. The incidence of VTE in the four groups was 15%, 9.0%, 6.0%, and 6.4%, respectively. The incidence of VTE was significantly lower in the groups receiving anticoagulant prophylaxis and the group selectively receiving no anticoagulant prophylaxis than in the group receiving no anticoagulants. Complications of fondaparinux therapy included hepatic dysfunction in 4 cases (4.0%), minor bleeding in 2 cases (2.0%), persistent wound drainage in 3 cases (3.0%), and eruption in 1 case (1.0%). The complications of enoxaparin therapy were persistent wound drainage in 1 case (1.0%) and progression of anemia in 1 case (1.0%). The incidence of VTE was low in patients who selectively received no anticoagulant prophylaxis, so we conclude that anticoagulant prophylaxis should be used selectively in THA cases. |
Keywords | total hip arthroplasty venous thromboembolism anticoagulant prophylaxis complications |
Amo Type | Erratum |
Publication Title | Acta Medica Okayama |
Published Date | 2015-10 |
Volume | volume69 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 325 |
End Page | 325 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 26490031 |
Related Url | http://doi.org/10.18926/AMO/53556 |
JaLCDOI | 10.18926/AMO/54807 |
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FullText URL | 70_6_449.pdf |
Author | Watanabe, Noriyuki| Sugimoto, Yoshihisa| Tanaka, Masato| Mazaki, Tetsuro| Arataki, Shinya| Takigawa, Tomoyuki| Kataoka, Masaki| Kunisada, Toshiyuki| Ozaki, Toshifumi| |
Abstract | Metastatic epidural spinal cord compression (MESCC) is a common complication in patients with a malignant tumor, but it is difficult to decide the proper time to perform the necessary surgery. Here we analyzed the prognostic factors for postoperative walking ability. We retrospectively reviewed the cases of 112 MESCC patients treated surgically at our institute and divided them into ambulatory (n= 88) and non-ambulatory (n=24) groups based on their American Spinal Injury Association (ASIA) Impairment Scale grades at the final follow-up. We also classified the patients preoperatively using the revised Tokuhashi score. We assessed the correlation between preoperative or intraoperative factors and postoperative walking ability in both groups. Of the 10 patients classified preoperatively as grade A or B, 2 (20 ) were ambulatory at the final follow-up. Of the 102 patients classified preoperatively as grade C, D or E, 86 (84 ) were ambulatory at the final follow-up (p<0.001). There were no significant differences between the groups in the average total Tokuhashi score. Our analysis revealed that the severity of paralysis significantly affects neurological recovery in patients with MESCC. Patients with MESCC should receive surgery before the preoperative ASIA Impairment Scale grade falls below grade C. |
Keywords | metastatic epidural spinal cord compression American Spinal Injury Association Impairment Scale Tokuhashi score walking ability prognostic factor |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2016-12 |
Volume | volume70 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 449 |
End Page | 453 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 28003669 |
FullText URL | JOS_24_2_337.pdf |
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Author | Fujiwara, Tomohiro| Kunisada, Toshiyuki| Takeda, Ken| Hasei, Joe| Nakata, Eiji| Mochizuki, Yusuke| Kiyono, Masahiro| Yoshida, Aki| Ozaki, Toshifumi| |
Published Date | 2019-03 |
Publication Title | Journal of Orthopaedic Science |
Volume | volume24 |
Issue | issue2 |
Publisher | Elsevier |
Start Page | 337 |
End Page | 341 |
ISSN | 0949-2658 |
NCID | AA11627828 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2018 The Japanese Orthopaedic Association. |
File Version | author |
PubMed ID | 30857616 |
DOI | 10.1016/j.jos.2018.09.017 |
Web of Science KeyUT | 000460662100026 |
Related Url | isVersionOf https://doi.org/10.1016/j.jos.2018.09.017 |
FullText URL | JOS_24_2_377.pdf |
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Author | Omori, Toshinori| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Takeda, Ken| Hasei, Joe| Yoshida, Aki| Yanai, Hiroyuki| Ozaki, Toshifumi| |
Published Date | 2019-03 |
Publication Title | Journal of Orthopaedic Science |
Volume | volume24 |
Issue | issue2 |
Publisher | Elsevier |
Start Page | 377 |
End Page | 381 |
ISSN | 0949-2658 |
NCID | AA11627828 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2016 The Japanese Orthopaedic Association |
File Version | author |
PubMed ID | 28187993 |
DOI | 10.1016/j.jos.2016.12.011 |
Web of Science KeyUT | 000460662100033 |
Related Url | isVersionOf https://doi.org/10.1016/j.jos.2016.12.011 |
FullText URL | CORR477_8_1892.pdf |
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Author | Kunisada, Toshiyuki| Fujiwara, Tomohiro| Hasei, Joe| Nakata, Eiji| Senda, Masuo| Ozaki, Toshifumi| |
Published Date | 2019-08 |
Publication Title | Clinical Orthopaedics and Related Research |
Volume | volume477 |
Issue | issue8 |
Publisher | Lippincott, Williams & Wilkins |
Start Page | 1892 |
End Page | 1901 |
ISSN | 0009-921X |
NCID | AA00607942 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 30985613 |
DOI | 10.1097/CORR.0000000000000764 |
Web of Science KeyUT | 000509664400024 |
Related Url | isVersionOf https://doi.org/10.1097/CORR.0000000000000764 |
FullText URL | fulltext.pdf Tables.pdf Fig1.tif Fig2.tif Supplementary Tables.pdf Supplementary Fig.pdf |
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Author | Yamamoto, Hiromasa| Namba, Kei| Yamamoto, Haruchika| Toji, Tomohiro| Soh, Junichi| Shien, Kazuhiko| Suzawa, Ken| Kurosaki, Takeshi| Otani, Shinji| Okazaki, Mikio| Sugimoto, Seiichiro| Yamane, Masaomi| Takahashi, Katsuhito| Kunisada, Toshiyuki| Oto, Takahiro| Toyooka, Shinichi| |
Keywords | Metastatic lung tumor Sarcoma Metastasectomy Survival rate Neutrophil-to-lymphocyte ratio (NLR) |
Note | This is a post-peer-review, pre-copyedit version of an article published in Surgery Today. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00595-020-02093-5. | |
Published Date | 2020-08-03 |
Publication Title | Surgery Today |
Publisher | Springer |
ISSN | 0941-1291 |
NCID | AA10824685 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 32747982 |
DOI | 10.1007/s00595-020-02093-5 |
Web of Science KeyUT | 000555382600001 |
Related Url | isVersionOf https://doi.org/10.1007/s00595-020-02093-5 |
FullText URL | fulltext.pdf Suppl. Info.pdf Suppl. Tables.xlsx |
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Author | Morita, Takuya| Fujiwara, Tomohiro| Yoshida, Aki| Uotani, Koji| Kiyono, Masahiro| Yokoo, Suguru| Hasei, Joe| Kunisada, Toshiyuki| Ozaki, Toshifumi| |
Keywords | Sarcoma Translational research |
Published Date | 2020-06-10 |
Publication Title | Scientific Reports |
Volume | volume10 |
Issue | issue1 |
Publisher | Nature |
Start Page | 9414 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2020 |
File Version | publisher |
PubMed ID | 32523124 |
DOI | 10.1038/s41598-020-66120-8 |
Web of Science KeyUT | 000560478900030 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-020-66120-8 |
FullText URL | fulltext.pdf |
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Author | Nakata, Eiji| Sugihara, Shinsuke| Sugawara, Yoshifumi| Nakahara, Ryuichi| Furumatsu, Takayuki| Tetsunaga, Tomonori| Kunisada, Toshiyuki| Nakanishi, Kazuo| Ozaki, Toshifumi| |
Keywords | bone metastasis multidisciplinary treatment skeletal-related event malignant spinal cord compression neurological deficit |
Published Date | 2020-02-20 |
Publication Title | Oncology Letters |
Volume | volume19 |
Issue | issue4 |
Publisher | Spandidos Publications |
Start Page | 3137 |
End Page | 3144 |
ISSN | 1792-1074 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Nakata et al. |
File Version | publisher |
PubMed ID | 32218864 |
DOI | 10.3892/ol.2020.11415 |
Web of Science KeyUT | 000523763900064 |
Related Url | isVersionOf https://doi.org/10.3892/ol.2020.11415 |
FullText URL | fulltext.pdf |
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Author | Joko, Ryoji| Yamada, Daisuke| Nakamura, Masahiro| Yoshida, Aki| Takihira, Shota| Takao, Tomoka| Lu, Ming| Sato, Kohei| Ito, Tatsuo| Kunisada, Toshiyuki| Nakata, Eiji| Ozaki, Toshifumi| Takarada, Takeshi| |
Keywords | PRRX1 Osteosarcoma Tumor malignancy Invasion Drug resistance Connectivity map analysis |
Published Date | 2021-01 |
Publication Title | Translational Oncology |
Volume | volume14 |
Issue | issue1 |
Publisher | Elsevier |
Start Page | 100960 |
ISSN | 1936-5233 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Authors. |
File Version | publisher |
PubMed ID | 33395745 |
DOI | 10.1016/j.tranon.2020.100960 |
Web of Science KeyUT | 000604582300006 |
Related Url | isVersionOf https://doi.org/10.1016/j.tranon.2020.100960 |
FullText URL | fulltext.pdf |
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Author | Kunisada, Toshiyuki| Hasei, Joe| Fujiwara, Tomohiro| Nakata, Eiji| Yokoo, Suguru| Demiya, Koji| Ozaki, Toshifumi| |
Published Date | 2020-12-09 |
Publication Title | Scientific Reports |
Volume | volume10 |
Issue | issue1 |
Publisher | Nature Research |
Start Page | 21578 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2020 |
File Version | publisher |
PubMed ID | 33299043 |
DOI | 10.1038/s41598-020-78409-9 |
Web of Science KeyUT | 000608956800002 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-020-78409-9 |
FullText URL | fulltext.pdf |
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Author | Fujiwara, Tomohiro| Healey, John| Ogura, Koichi| Yoshida, Aki| Kondo, Hiroya| Hata, Toshiaki| Kure, Miho| Tazawa, Hiroshi| Nakata, Eiji| Kunisada, Toshiyuki| Fujiwara, Toshiyoshi| Ozaki, Toshifumi| |
Keywords | sarcoma tumor-associated macrophage prognosis clinical trial immunotherapy |
Published Date | 2021-03-03 |
Publication Title | Cancers |
Volume | volume13 |
Issue | issue5 |
Publisher | MDPI |
Start Page | 1086 |
ISSN | 2072-6694 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 by the authors. |
File Version | publisher |
PubMed ID | 33802565 |
NAID | 120007008531 |
DOI | 10.3390/cancers13051086 |
Web of Science KeyUT | 000627955600001 |
Related Url | isVersionOf https://doi.org/10.3390/cancers13051086 |
FullText URL | fulltext.pdf |
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Author | Yokoo, Suguru| Fujiwara, Tomohiro| Yoshida, Aki| Uotani, Koji| Morita, Takuya| Kiyono, Masahiro| Hasei, Joe| Nakata, Eiji| Kunisada, Toshiyuki| Iwata, Shintaro| Yonemoto, Tsukasa| Ueda, Koji| Ozaki, Toshifumi| |
Keywords | liquid biopsy synovial sarcoma monocarboxylate transporter 1 extracellular vesicles non-invasive biomarker |
Published Date | 2021-04-11 |
Publication Title | Cancers |
Volume | volume13 |
Issue | issue8 |
Publisher | MDPI |
Start Page | 1823 |
ISSN | 2072-6694 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 by the authors. |
File Version | publisher |
PubMed ID | 33920416 |
NAID | 120007037389 |
DOI | 10.3390/cancers13081823 |
Web of Science KeyUT | 000644023400001 |
Related Url | isVersionOf https://doi.org/10.3390/cancers13081823 |
FullText URL | fulltext.pdf |
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Author | Ise, Masato| Nakata, Eiji| Katayama, Yoshimi| Hamada, Masanori| Kunisada, Toshiyuki| Fujiwara, Tomohiro| Nakahara, Ryuichi| Takihira, Shouta| Sato, Kohei| Akezaki, Yoshiteru| Senda, Masuo| Ozaki, Toshifumi| |
Keywords | psychological distress distress and impact thermometer bone and soft tissue tumor surgery |
Published Date | 2021-05-01 |
Publication Title | Healthcare |
Volume | volume9 |
Issue | issue5 |
Publisher | MDPI |
Start Page | 566 |
ISSN | 2227-9032 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 by the authors. |
File Version | publisher |
NAID | 120007042388 |
DOI | 10.3390/healthcare9050566 |
Web of Science KeyUT | 000654015500001 |
Related Url | isVersionOf https://doi.org/10.3390/healthcare9050566 |
FullText URL | fulltext.pdf |
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Author | Omori, Toshinori| Tazawa, Hiroshi| Yamakawa, Yasuaki| Osaki, Shuhei| Hasei, Joe| Sugiu, Kazuhisa| Komatsubara, Tadashi| Fujiwara, Tomohiro| Yoshida, Aki| Kunisada, Toshiyuki| Urata, Yasuo| Kagawa, Shunsuke| Ozaki, Toshifumi| Fujiwara, Toshiyoshi| |
Keywords | Gastric yolk sac Tumor-like carcinoma Adenocarcinoma; Alpha-fetoprotein |
Published Date | 2021-04-22 |
Publication Title | PLoS ONE |
Volume | volume16 |
Issue | issue4 |
Publisher | Public Library Science |
Start Page | e0250643 |
ISSN | 1932-6203 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 Omori et al. |
File Version | publisher |
PubMed ID | 33886686 |
NAID | 120007045007 |
DOI | 10.1371/journal.pone.0250643 |
Web of Science KeyUT | 000644138300019 |
Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0250643 |
FullText URL | fulltext20210628-1.pdf Figure_20210628-1.pdf Supple_Figure_20210628-1.pdf Supple_Table_20210628-1.pdf |
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Author | Sugiu, Kazuhisa| Tazawa, Hiroshi| Hasei, Joe| Yamakawa, Yasuaki| Omori, Toshinori| Komatsubara, Tadashi| Mochizuki, Yusuke| Kondo, Hiroya| Osaki, Shuhei| Fujiwara, Tomohiro| Yoshida, Aki| Kunisada, Toshiyuki| Ueda, Koji| Urata, Yasuo| Kagawa, Shunsuke| Ozaki, Toshifumi| Fujiwara, Toshiyoshi| |
Keywords | Osteosarcoma Chemoresistance MDR1 Oncolytic adenovirus p53 |
Note | This is a post-peer-review, pre-copyedit version of an article published in Cancer Chemotherapy and Pharmacology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00280-021-04310-5| |
Published Date | 2021-6-10 |
Publication Title | Cancer Chemotherapy and Pharmacology |
Volume | volume88 |
Issue | issue3 |
Publisher | Springer Science and Business Media LLC |
Start Page | 513 |
End Page | 524 |
ISSN | 0344-5704 |
NCID | AA00598397 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 34114067 |
DOI | 10.1007/s00280-021-04310-5 |
Web of Science KeyUT | 000659839700002 |
Related Url | isVersionOf https://doi.org/10.1007/s00280-021-04310-5 |
Author | Hasei, Joe| Sasaki, Tsuyoshi| Tazawa, Hiroshi| Osaki, Shuhei| Yamakawa, Yasuaki| Kunisada, Toshiyuki| Yoshida, Aki| Hashimoto, Yuuri| Onishi, Teppei| Uno, Futoshi| Kagawa, Shunsuke| Urata, Yasuo| Ozaki, Toshifumi| Fujiwara, Toshiyoshi| |
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Published Date | 2013-03 |
Publication Title | Molecular Cancer Therapeutics |
Volume | volume12 |
Issue | issue3 |
Content Type | Journal Article |
Author | Yoneda, Yasushi| Ito, Sachio| Kunisada, Toshiyuki| Morimoto, Yuki| Kanzaki, Hirotaka| Yoshida, Aki| Shimizu, Kenji| Ozaki, Toshifumi| Ouchida, Mamoru| |
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Published Date | 2013-10-09 |
Publication Title | PLoS ONE |
Volume | volume8 |
Issue | issue10 |
Content Type | Journal Article |
FullText URL | fulltext.pdf figures.pdf SuppleFigures.pdf |
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Author | Mochizuki, Yusuke| Tazawa, Hiroshi| Demiya, Koji| Kure, Miho| Kondo, Hiroya| Komatsubara, Tadashi| Sugiu, Kazuhisa| Hasei, Joe| Yoshida, Aki| Kunisada, Toshiyuki| Urata, Yasuo| Kagawa, Shunsuke| Ozaki, Toshifumi| Fujiwara, Toshiyoshi| |
Keywords | Oncolytic adenovirus hTERT Immunogenic cell death ATP CD8 |
Note | This is a post-peer-review, pre-copyedit version of an article published in Cancer Immunology, Immunotherapy. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00262-020-02774-7.| |
Published Date | 2020-11-05 |
Publication Title | Cancer Immunology, Immunotherapy |
Volume | volume70 |
Publisher | Springer |
Start Page | 1405 |
End Page | 1417 |
ISSN | 0340-7004 |
NCID | AA00598499 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 33151368 |
DOI | 10.1007/s00262-020-02774-7 |
Web of Science KeyUT | 000586350500002 |
Related Url | isVersionOf https://doi.org/10.1007/s00262-020-02774-7 |
FullText URL | fulltext.pdf |
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Author | Fujiwara, Tomohiro| Nakata, Eiji| Kunisada, Toshiyuki| Ozaki, Toshifumi| Kawai, Akira| |
Keywords | Alveolar soft part sarcoma Survival Surgery Chemotherapy Pazopanib |
Published Date | 2022-08-15 |
Publication Title | BMC Cancer |
Volume | volume22 |
Issue | issue1 |
Publisher | BMC |
Start Page | 891 |
ISSN | 1471-2407 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2022. |
File Version | publisher |
PubMed ID | 35971085 |
DOI | 10.1186/s12885-022-09968-5 |
Web of Science KeyUT | 000840842400002 |
Related Url | isVersionOf https://doi.org/10.1186/s12885-022-09968-5 |