| Author | Ichiba, Shingo| |
|---|---|
| Published Date | 2012-04-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Bárcenas, Noé| |
|---|---|
| Published Date | 2014-01 |
| Publication Title | Mathematical Journal of Okayama University |
| Volume | volume56 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/mjou/52071 |
| Author | Yamamoto, Michio| Nishishita, Soichi| Hiramatu, Osamu| Iida, Srosuke| Nokihara, Yosimasa| Kumada, Yasumasa| |
|---|---|
| Published Date | 1967-10-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume79 |
| Issue | issue9-10 |
| Content Type | Journal Article |
| Author | Kobayashi, Masato| |
|---|---|
| Published Date | 2015-01 |
| Publication Title | Mathematical Journal of Okayama University |
| Volume | volume57 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/mjou/53047 |
| Author | Tsuchiya, Masao| |
|---|---|
| Published Date | 1987-02-28 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume99 |
| Issue | issue1-2 |
| Content Type | Journal Article |
| Author | Kosaka, K.| Seki, M.| |
|---|---|
| Published Date | 1921-01-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume33 |
| Issue | issue372 |
| Content Type | Journal Article |
| Author | Rai, Kammei| Takigawa, Nagio| Ito, Sachio| Kashihara, Hiromi| Ichihara, Eiki| Yasuda, Tatsuji| Shimizu, Kenji| Tanimoto, Mitsune| Kiura, Katsuyuki| |
|---|---|
| Published Date | 2012-12-03 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Suehisa, Hiroshi| Toyooka, Shinichi| Hotta, Katsuyuki| Uchida, Akiko| Soh, Junichi| Fujiwara, Yoshiro| Matsuo, Keitaro| Ouchida, Mamoru| Takata, Minoru| Kiura, Katsuyuki| Date, Hiroshi| |
|---|---|
| Published Date | 2008-12-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume120 |
| Issue | issue3 |
| Content Type | Journal Article |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Fujiwara, Toshiya| Shien, Kazuhiko| Matsuura, Motoki| Soh, Junichi| Yamamoto, Hiromasa| Takao, Soshi| Maki, Yuho| Ueno, Tsuyoshi| Sugimoto, Ryujiro| Suzawa, Ken| Okazaki, Mikio| Tao, Hiroyuki| Hayama, Makio| Kataoka, Masafumi| Sano, Yoshifumi| Inokawa, Hidetoshi| Yamashita, Motohiro| Kawamata, Osamu| Kataoka, Kazuhiko| Toyooka, Shinichi| |
| Note | The version of record of this article, first published in Annals of Surgical Oncology, is available online at Publisher’s website: http://dx.doi.org/10.1245/s10434-023-13791-y| |
| Published Date | 2023-06-25 |
| Publication Title | Annals of Surgical Oncology |
| Volume | volume30 |
| Issue | issue11 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 6697 |
| End Page | 6702 |
| ISSN | 1068-9265 |
| NCID | AA11016573 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37355521 |
| DOI | 10.1245/s10434-023-13791-y |
| Web of Science KeyUT | 001019888600007 |
| Related Url | isVersionOf https://doi.org/10.1245/s10434-023-13791-y |
| Author | Toyooka, Shinichi| Date, Hiroshi| |
|---|---|
| Published Date | 2008-05-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume120 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/62806 |
|---|---|
| FullText URL | 75_6_677.pdf |
| Author | Tani Kazumasa| Mitsui, Takashi| Mishima, Sakurako| Ohira, Akiko| Maki, Jota| Eto, Eriko| Hayata, Kei| Nakamura, Keiichiro| Masuyama, Hisashi| |
| Abstract | Extravillous trophoblast (EVT) invasion is important for embryo implantation, placental development, and successful remodeling of the uterine spiral artery. Endocrine gland derived-vascular endothelial growth factor (EG-VEGF) and matrix metalloproteinases (MMPs) are implicated in EVT invasion; however, the high con-centrations found in pregnancy pathologies have not been investigated in non-tumor trophoblasts. The roles of EG-VEGF, prokineticin receptors (PROKR1/2), MMP-2, and MMP-9 in EVT invasion during spiral artery remodeling were evaluated using human EVT from HTR-8/SVneo cell lines. The expression of MMP-2, MMP-9, and mitogen-activated protein kinase (MAPK), and Akt pathways in HTR-8/SVneo cells treated with recom-binant EG-VEGF alongside anti-PROKR1 and/or anti-PROKR2 antibodies was evaluated using quantitative reverse transcription-PCR and western blotting. Wound-healing and cell invasion assays were performed to assess the migration and invasion of these treated cells. Interestingly, 20 nM EG-VEGF activated ERK1/2 sig-naling and upregulated MMP-2 and MMP-9. This effect was suppressed by anti-PROKR2 antibody via ERK1/2 downregulation. Anti-PROKR2 antibody inhibited the migration and invasion of EG-VEGF-stimulated HTR-8/SVneo cells. Elevated concentrations of EG-VEGF enhance EVT invasion in a human trophoblast cell line by upregulating MMP-2 and MMP-9 via PROKR2. These new insights into the regulation of epithelial cell invasion may help in developing therapeutic interventions for placental-related diseases during pregnancy. |
| Keywords | endocrine gland-derived vascular endothelial growth factor prokineticin extravillous trophoblast matrix metalloproteinase obstetric diseases |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-12 |
| Volume | volume75 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 677 |
| End Page | 684 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34955534 |
| Web of Science KeyUT | 000735297900002 |
| NAID | 120007180286 |
| Author | Naito, H.| Takeda, Y.| Danura, T.| Kass, I. S.| Morita, K.| |
|---|---|
| Published Date | 2013-04-03 |
| Publication Title | Neuroscience |
| Volume | volume235 |
| Content Type | Journal Article |
| Author | Kukida, Yoshiaki| |
|---|---|
| Published Date | 1959-09-20 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume71 |
| Issue | issue10-1 |
| Content Type | Journal Article |
| Author | Kukida, Yoshiaki| |
|---|---|
| Published Date | 1959-09-20 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume71 |
| Issue | issue10-1 |
| Content Type | Journal Article |
| Author | Yamada, Makoto| |
|---|---|
| Published Date | 1992-12 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume104 |
| Issue | issue11-12 |
| Content Type | Journal Article |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Asano, Yosuke| Matsumoto, Yoshinori| Wada, Jun| Rottapel, Robert| |
| Keywords | E3-ubiquitin ligases ubiquitylation proteasomal degradation osteoimmunology cherubism |
| Published Date | 2023-02-23 |
| Publication Title | Frontiers in Immunology |
| Volume | volume14 |
| Publisher | Frontiers Media |
| Start Page | 1120710 |
| ISSN | 1664-3224 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Asano, Matsumoto, Wada and Rottapel. |
| File Version | publisher |
| PubMed ID | 36911671 |
| DOI | 10.3389/fimmu.2023.1120710 |
| Web of Science KeyUT | 000945836300001 |
| Related Url | isVersionOf https://doi.org/10.3389/fimmu.2023.1120710 |
| Author | Suzuki, Shigeo| |
|---|---|
| Published Date | 1987-12-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume99 |
| Issue | issue11-12 |
| Content Type | Journal Article |
| Author | Suzuki, Shigeki| |
|---|---|
| Published Date | 1990-04 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume102 |
| Issue | issue3-4 |
| Content Type | Journal Article |
| Author | Suh, Moon-Suk| |
|---|---|
| Published Date | 1994-02 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume106 |
| Issue | issue1-2 |
| Content Type | Journal Article |
| FullText URL | mjou_065_023_034.pdf |
|---|---|
| Author | Kato, Ryo| |
| Abstract | Let E(2) be the second Johnson-Wilson spectrum at the prime 3. In this paper, we show that some beta elements exist in the homotopy groups of the E(2)-localized sphere spectrum with a grading over the Picard group of the stable homotopy category of E(2)-local spectra. |
| Keywords | Stable homotopy of spheres Picard group |
| Published Date | 2023-01 |
| Publication Title | Mathematical Journal of Okayama University |
| Volume | volume65 |
| Issue | issue1 |
| Publisher | Department of Mathematics, Faculty of Science, Okayama University |
| Start Page | 23 |
| End Page | 34 |
| ISSN | 0030-1566 |
| NCID | AA00723502 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright ©2023 by the Editorial Board of Mathematical Journal of Okayama University |
