検索結果 - 岡山大学学術成果リポジトリ

Endoscopic features of oxyntic gland adenoma and gastric adenocarcinoma of the fundic gland type differ between patients with and without Helicobacter pylori infection: a retrospective observational study

フルテキストURL	fulltext.pdf
著者	Iwamuro, Masaya\| Kusumoto, Chiaki\| Nakagawa, Masahiro\| Matsueda, Kazuhiro\| Kobayashi, Sayo\| Yoshioka, Masao\| Inaba, Tomoki\| Toyokawa, Tatsuya\| Sakaguchi, Chihiro\| Tanaka, Shouichi\| Tanaka, Takehiro\| Okada, Hiroyuki\|
キーワード	Gastric neoplasms Oxyntic gland adenoma Gastric adenocarcinoma of the fundic gland type
発行日	2022-06-12
出版物タイトル	BMC Gastroenterology
巻	22巻
号	1号
出版者	BMC
開始ページ	294
ISSN	1471-230X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022.
論文のバージョン	publisher
PubMed ID	35692036
DOI	10.1186/s12876-022-02368-w
Web of Science KeyUT	000809663500001
関連URL	isVersionOf https://doi.org/10.1186/s12876-022-02368-w

Adenomatoid mesothelioma arising from the diaphragm: a case report and review of the literature

フルテキストURL	fulltext.pdf
著者	Kawabe, Kenta\| Sato, Hiroki\| Kitano, Akiko\| Yoshida, Ryuichi\| Yasui, Kazuya\| Umeda, Yuzo\| Yoshida, Kazuhiro\| Fuji, Tomokazu\| Kumano, Kenjiro\| Takagi, Kosei\| Kagoura, Masaaki\| Yagi, Takahito\| Fujiwara, Toshiyoshi\|
キーワード	Adenomatoid mesothelioma Adenomatoid tumor Mesothelial tumor Diaphragm Peritoneal
発行日	2022-05-30
出版物タイトル	Journal Of Medical Case Reports
巻	16巻
号	1号
出版者	BMC
開始ページ	228
ISSN	1752-1947
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022.
論文のバージョン	publisher
PubMed ID	35637533
DOI	10.1186/s13256-022-03420-9
Web of Science KeyUT	000805574600001
関連URL	isVersionOf https://doi.org/10.1186/s13256-022-03420-9

The resolution of immunofluorescent pathological images affects diagnosis for not only artificial intelligence but also human

フルテキストURL	K0006578_abstract_review.pdf K0006578_fulltext.pdf
著者	髙橋謙作\|
発行日	2022-03-25
資料タイプ	学位論文
学位授与番号	甲第6578号
学位授与年月日	2022-03-25
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© 2021 The Author(s)

Modulation of p53 expression in cancer-associated fibroblasts prevents peritoneal metastasis of cancer

フルテキストURL	fulltext.pdf
著者	Ogawa, Toshihiro\| Kikuchi, Satoru\| Tabuchi, Motoyasu\| Mitsui, Ema\| Une, Yuta\| Tazawa, Hiroshi\| Kuroda, Shinji\| Noma, Kazuhiro\| Ohara, Toshiaki\| Kagawa, Shunsuke\| Urata, Yasuo\| Fujiwara, Toshiyoshi\|
発行日	2022-06-16
出版物タイトル	Molecular Therapy-Oncolytics
巻	25巻
出版者	Cell Press
開始ページ	249
終了ページ	261
ISSN	2372-7705
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Author(s).
論文のバージョン	publisher
PubMed ID	35615263
DOI	10.1016/j.omto.2022.04.009
Web of Science KeyUT	000800437000008
関連URL	isVersionOf https://doi.org/10.1016/j.omto.2022.04.009

Historical and pathological overview of Castleman disease

フルテキストURL	fulltext.pdf
著者	Nishimura, Midori Filiz\| Nishimura, Yoshito\| Nishikori, Asami\| Yoshino, Tadashi\| Sato, Yasuharu\|
キーワード	Castleman disease idiopathic multicentric Castleman disease TAFRO syndrome idiopathic plasmacytic lymphadenopathy with polyclonal hyperimmunoglobulinemia
発行日	2022-04-27
出版物タイトル	Journal Of Clinical And Experimental Hematopathology
出版者	The Japanese Society for Lymphoreticular Tissue Research
開始ページ	21036
ISSN	1346-4280
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Japanese Society for Lymphoreticular Tissue Research
論文のバージョン	publisher
PubMed ID	35474035
DOI	10.3960/jslrt.21036
Web of Science KeyUT	000796525400001
関連URL	isVersionOf https://doi.org/10.3960/jslrt.21036

Idiopathic multicentric Castleman disease with positive antiphospholipid antibody: atypical and undiagnosed autoimmune disease?

フルテキストURL	fulltext.pdf
著者	Nishimura, Yoshito\| Nishikori, Asami\| Sawada, Haruki\| Czech, Torrey\| Otsuka, Yuki\| Nishimura, Midori Filiz\| Mizuno, Hiroki\| Sawa, Naoki\| Momose, Shuji\| Ohsawa, Kumiko\| Otsuka, Fumio\| Sato, Yasuharu\|
キーワード	idiopathic plasmacytic lymphadenopathy multicentric Castleman disease autoimmune anti-phospholipid syndrome
発行日	2022
出版物タイトル	Journal Of Clinical And Experimental Hematopatholo
出版者	The Japanese Society for Lymphoreticular Tissue Research
開始ページ	21038
ISSN	1346-4280
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Japanese Society for Lymphoreticular Tissue Research
論文のバージョン	publisher
PubMed ID	35249898
DOI	10.3960/jslrt.21038
Web of Science KeyUT	000796251200001
関連URL	isVersionOf https://doi.org/10.3960/jslrt.21038

One-step nucleic acid amplification for intraoperative diagnosis of lymph node metastasis in lung cancer patients: a single-center prospective study

フルテキストURL	fulltext.pdf
著者	Namba, Kei\| Suzawa, Ken\| Shien, Kazuhiko\| Miura, Akihiro\| Takahashi, Yuta\| Miyauchi, Shunsaku\| Araki, Kota\| Nakata, Kentaro\| Tomida, Shuta\| Tanaka, Shin\| Miyoshi, Kentaroh\| Otani, Shinji\| Yamamoto, Hiromasa\| Okazaki, Mikio\| Sugimoto, Seiichiro\| Soh, Junichi\| Yamane, Masaomi\| Toyooka, Shinichi\|
発行日	2022-05-04
出版物タイトル	Scientific Reports
巻	12巻
号	1号
出版者	Nature Portfolio
開始ページ	7297
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	35508484
DOI	10.1038/s41598-022-11064-4
Web of Science KeyUT	000790941900040
関連URL	isVersionOf https://doi.org/10.1038/s41598-022-11064-4

Prognostic Factors in Endodontic Surgery Using an Endoscope: A 1 Year Retrospective Cohort Study

フルテキストURL	fulltext.pdf
著者	Sukegawa, Shintaro\| Shimizu, Rieko\| Sukegawa, Yuka\| Hasegawa, Kazuaki\| Ono, Sawako\| Fujimura, Ai\| Yamamoto, Izumi\| Nakano, Keisuke\| Takabatake, Kiyofumi\| Kawai, Hotaka\| Nagatsuka, Hitoshi\| Furuki, Yoshihiko\|
キーワード	retrospective cohort study endoscope endodontic surgery prognostic factors
発行日	2022-05-07
出版物タイトル	Materials
巻	15巻
号	9号
出版者	MDPI
開始ページ	3353
ISSN	1996-1944
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35591687
DOI	10.3390/ma15093353
Web of Science KeyUT	000794818400001
関連URL	isVersionOf https://doi.org/10.3390/ma15093353

Clinicopathological Characteristics of Superficial Barrett's Adenocarcinoma in a Japanese Population: A Retrospective, Multicenter Study

フルテキストURL	fulltext.pdf
著者	Hamada, Kenta\| Kanzaki, Hiromitsu\| Miyahara, Koji\| Nakagawa, Masahiro\| Mouri, Hirokazu\| Mizuno, Motowo\| Takahashi, Sakuma\| Hori, Shinichiro\| Nasu, Junichiro\| Tsuzuki, Takao\| Miyaike, Jiro\| Takenaka, Ryuta\| Yamauchi, Kenji\| Kobayashi, Sayo\| Toyokawa, Tatsuya\| Inoue, Masafumi\| Nishimura, Mamoru\| Matsubara, Minoru\| Tomoda, Jun\| Yamasaki, Yasushi\| Tanaka, Takehiro\| Shirakawa, Yasuhiro\| Kawahara, Yoshiro\| Fujiwara, Toshiyoshi\| Okada, Hiroyuki\| Okayama Gut Study Group\|
キーワード	Barrett's adenocarcinoma endoscopic resection long -segment Barrett's esophagus metachronous lesion short -segment Barrett's esophagus surgery
発行日	2022-04-15
出版物タイトル	INTERNAL MEDICINE
巻	61巻
号	8号
出版者	The Japanese Society of Internal Medicine
開始ページ	1115
終了ページ	1123
ISSN	0918-2918
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Japanese Society of Internal Medicine
論文のバージョン	publisher
PubMed ID	35431302
DOI	10.2169/internalmedicine.6942-20
Web of Science KeyUT	000789463700001
関連URL	isVersionOf https://doi.org/10.2169/internalmedicine.6942-20

Identification of osteoporosis using ensemble deep learning model with panoramic radiographs and clinical covariates

フルテキストURL	fulltext.pdf
著者	Sukegawa, Shintaro\| Fujimura, Ai\| Taguchi, Akira\| Yamamoto, Norio\| Kitamura, Akira\| Goto, Ryosuke\| Nakano, Keisuke\| Takabatake, Kiyofumi\| Kawai, Hotaka\| Nagatsuka, Hitoshi\| Furuki, Yoshihiko\|
発行日	2022-04-12
出版物タイトル	Scientific Reports
巻	12巻
号	1号
出版者	Nature Portfolio
開始ページ	6088
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	35413983
DOI	10.1038/s41598-022-10150-x
Web of Science KeyUT	000782202600026
関連URL	isVersionOf https://doi.org/10.1038/s41598-022-10150-x

Late-Onset Hypogonadism in a Male Patient with Long COVID Diagnosed by Exclusion of ME/CFS

フルテキストURL	fulltext.pdf
著者	Soejima, Yoshiaki\| Otsuka, Yuki\| Tokumasu, Kazuki\| Nakano, Yasuhiro\| Harada, Ko\| Nakamoto, Kenta\| Sunada, Naruhiko\| Sakurada, Yasue\| Hasegawa, Kou\| Hagiya, Hideharu\| Ueda, Keigo\| Otsuka, Fumio\|
キーワード	general fatigue free testosterone late-onset hypogonadism long COVID post-COVID condition
発行日	2022-04-13
出版物タイトル	Medicina-Lithuania
巻	58巻
号	4号
出版者	MDPI
開始ページ	536
ISSN	1010-660X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35454374
DOI	10.3390/medicina58040536
Web of Science KeyUT	000785092200001
関連URL	isVersionOf https://doi.org/10.3390/medicina58040536

Implications of immune cells in oncolytic herpes simplex virotherapy for glioma

フルテキストURL	fulltext20220428-2.pdf table20220428-2.pdf figure20220428-2.pdf
著者	Otani, Yoshihiro\| Yoo, Ji Young\| Shimizu, Toshihiko\| Kurozumi, Kazuhiko\| Date, Isao\| Kaur, Balveen\|
キーワード	Oncolytic virus Immune cells Glioma
備考	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10014-022-00431-8\|
発行日	2022-4-6
出版物タイトル	Brain Tumor Pathology
巻	39巻
出版者	Springer Science and Business Media LLC
開始ページ	57
終了ページ	64
ISSN	1433-7398
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s), under exclusive licence to The Japan Society of Brain Tumor Pathology 2022
論文のバージョン	author
PubMed ID	35384530
DOI	10.1007/s10014-022-00431-8
Web of Science KeyUT	000781179200001
関連URL	isVersionOf https://doi.org/10.1007/s10014-022-00431-8

A Case of Primary Osteosarcoma of the Mandible That Responded to Preoperative Chemotherapy: p16 as a Potential Prognostic Factor

JaLCDOI	10.18926/AMO/63428
フルテキストURL	76_2_229.pdf
著者	Kono, Takashi\| Monden, Nobuya\| Chikuie, Nobuyuki\| Taruya, Takayuki\| Hamamoto, Takao\| Ishino, Takashi\| Ueda, Tsutomu\| Takeno, Sachio\|
抄録	We report a case of mandibular osteosarcoma in a Japanese woman in her 70s who was p16-positive. Despite the rapid growth of the tumor, the patient responded well to chemotherapy and was then able to undergo surgery. Head and neck osteosarcoma (HNOS) is a very rare cancer, and although the importance of surgery has been pointed out, the effectiveness of chemotherapy is unclear. Resection margin negativity and response to chemotherapy have been reported as prognostic factors; another report assessed the effectiveness of the immunohistochemical expression of p16 protein as a predictor of response to chemotherapy.
キーワード	head and neck osteosarcomas tumor suppressor p16
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	229
終了ページ	233
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503452
Web of Science KeyUT	000792291900006

Mediastinal and Hilar Lymph Node Metastases from Renal Cell Carcinoma with Concomitant Lung Carcinoma: A Rare Case with Unique Diagnostic Challenges

JaLCDOI	10.18926/AMO/63427
フルテキストURL	76_2_225.pdf
著者	Mori, Yu\| Sano, Yoshifumi\| Sugimoto, Ryujiro\| Sakao, Nobuhiko\| Ryuko, Tsuyoshi\| Takeda, Masashi\| Kitazawa, Riko\| Yukumi, Shungo\| Izutani, Hironori\|
抄録	A 75-year-old man presented to our hospital 1 year after partial renal resection for clear cell carcinoma. A right lower lobe lung nodule noted at the time of surgery had increased to 3.0 cm in diameter and was confirmed as squamous cell lung carcinoma by bronchoscopic cytology. Computed tomography had also revealed paratracheal lymph node swelling. He underwent right lower lobectomy with lymph node dissection by video-assisted thoracic surgery. Pathological examination confirmed squamous cell carcinoma of the lung but diagnosed the right hilar and mediastinal lymph node metastases as clear cell carcinoma.
キーワード	renal cell carcinoma primary lung cancer double cancer mediastinal lymph node metastasis hilar lymph node metastasis
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	225
終了ページ	228
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503451
Web of Science KeyUT	000792291900005

A Pediatric Case of Cauda Equina Dermoid Cyst Resected by Minimally Invasive Unilateral Hemilaminectomy

JaLCDOI	10.18926/AMO/63426
フルテキストURL	76_2_217.pdf
著者	Yabuno, Satoru\| Sasada, Susumu\| Umakoshi, Michiari\| Nagase, Takayuki\| Sugahara, Chiaki\| Kawauchi, Satoshi\| Yasuhara, Takao\| Date, Isao\|
抄録	A 3-year-old boy had difficulty sitting up and walking for several months. Magnetic resonance imaging (MRI) revealed an intradural tumor at the L3-4 level. The tumor was successfully resected by unilateral hemilaminectomy and diagnosed as dermoid cyst. The patient had an uneventful postoperative course without pain, and MRI found no recurrence after surgery. A small bone defect remained that might be favorably reconstructed with autologous and artificial bone. Hemilaminectomy allowed us to resect the cauda equina dermoid cyst with minimal invasiveness. Pediatric patients require follow-up as they are more likely to experience spinal deformity or instability after surgery.
キーワード	cauda equina tumor child dermoid cyst hemilaminectomy spinal tumor
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	217
終了ページ	223
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503450
Web of Science KeyUT	000792291900004

Silica-associated systemic lupus erythematosus with lupus nephritis and lupus pneumonitis A case report and a systematic review of the literature

フルテキストURL	fulltext.pdf
著者	Fukushima, Kazuhiko\| Uchida, Haruhito A.\| Fuchimoto, Yasuko\| Mifune, Tomoyo\| Watanabe, Mayu\| Tsuji, Kenji\| Tanabe, Katsuyuki\| Kinomura, Masaru\| Kitamura, Shinji\| Miyamoto, Yosuke\| Wada, Sae\| Koyanagi, Taisaku\| Sugiyama, Hitoshi\| Kishimoto, Takumi\| Wada, Jun\|
キーワード	lupus nephritis lupus pneumonitis silicosis SLE
発行日	2022-02-18
出版物タイトル	Medicine
巻	101巻
号	7号
出版者	Lippincott Williams & Wilkins
開始ページ	e28872
ISSN	0025-7974
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 the Author(s).
論文のバージョン	publisher
PubMed ID	35363197
DOI	10.1097/MD.0000000000028872
Web of Science KeyUT	000776738500059
関連URL	isVersionOf https://doi.org/10.1097/MD.0000000000028872

MRI multiparametric scoring system for pial blood supply of intracranial meningiomas

フルテキストURL	fulltext.pdf
著者	Higaki, Fumiyo\| Inoue, Satoshi\| Oda, Wakako\| Matsusue, Eiji\| Hiraki, Takao\|
キーワード	pial blood supply peritumoral brain edema arachnoid plane peritumoral flow void magnetic resonance imaging
発行日	2022-04-08
出版物タイトル	Acta Radiologica Open
巻	11巻
号	4号
出版者	Sage Publications Ltd.
ISSN	2058-4601
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	35425642
DOI	10.1177/20584601221091208
Web of Science KeyUT	000780184200001
関連URL	isVersionOf https://doi.org/10.1177/20584601221091208

Clinicopathological Features and Surgical Outcomes of Small Bowel Metastasis from Renal Cell Carcinoma

JaLCDOI	10.18926/AMO/63409
フルテキストURL	76_2_155.pdf
著者	Kimura, Jiro\| Okabayashi, Takehiro\| Sui, Kenta\| Tabuchi, Motoyasu\| Iwata, Jun\| Hata, Yasuhiro\| Iiyama, Tatsuo\| Ono, Noriaki\|
抄録	Small bowel metastasis from renal cell carcinoma (RCC) is rare, and its clinicopathological characteristics are unclear; thus, we revisited the concept of this tumor and reviewed its diagnostic and treatment modalities. We filtered MEDLINE searches of articles published in English between 1950 and 2019, and identified 100 patients who had undergone treatment, including 1 patient from our clinic. We extracted patient characteristics, treatment, and prognostic data, resulting in clinicopathological data on 100 patients (83 men, 17 women). Mean age was 63 years (range, 16-86 years). Tumor sites were duodenum, jejunum, ileum, and multiple sites in 30, 37, 25, and 7 patients, respectively. The 1-, 3-, and 5-year overall survival rates after diagnosis were 53.0%, 36.0%, and 36.0%. Curative resection patients showed 62.1% 5-year survival after surgery, vs. 27.5% in noncurative surgical management cases. Good prognoses can be expected if these tumors are identified early for complete removal. Surgery is the only curative option. To determine the best management strategy and improve prognostic accuracy, we continue to collect and analyze epidemiological and pathological data. Although this condition is rare, surgery should be considered if curative resection is expected. Prognosis after curative resection is not poor, but recurrence is not unlikely.
キーワード	renal cell carcinoma small bowel metastasis intestine tumor
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	155
終了ページ	165
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503443
Web of Science KeyUT	000792374900007

Grade of Subchondral Insufficiency Fracture of the Knee and the Presence of a Posterior Shiny-Corner Lesion are Correlated with Duration of Medial Meniscus Posterior Root Tear in Women

JaLCDOI	10.18926/AMO/63405
フルテキストURL	76_2_121.pdf
著者	Okazaki, Yuki\| Furumatsu, Takayuki\| Hiranaka, Takaaki\| Kamatsuki, Yusuke\| Nakata, Eiji\| Tetsunaga, Tomonori\| Yamane, Kentaro\| Ozaki, Toshifumi\|
抄録	Bone marrow edema (BME) after meniscus injury and risk factors for subchondral insufficiency fracture of the knee (SIFK) have been reported. However, their association with medial meniscus posterior root tear (MMPRT) remains unknown. We investigated the association of BME volume (BME-V), posterior shinycorner lesion (PSCL), and SIFK with MMPRT to examine the correlations between BME-V and medial meniscus extrusion (MME), PSCL and duration from injury to the time of magnetic resonance imaging (duration), and SIFK and duration. Twenty-nine patients who underwent surgery for MMPRT were included (mean age, 59.2; range, 39-84). The presence of PSCL, femoral BME-V (cm3), and SIFK grade (1-4) were evaluated. Preoperative factors, such as MME (mm) and duration (weeks), were investigated using multivariate linear/ logistic regression analyses. Multivariate linear regression analysis revealed duration as a significant factor for high-grade SIFK (p<0.01). Multivariate logistic regression analysis revealed duration as a significant factor for the presence of PSCL (odds ratio=0.94, p<0.05). A long duration of MMPRT leads to severe MME and highgrade SIFK (3 and 4), often resulting in knee arthroplasty. Early diagnosis of MMPRT and pullout repair can prevent severe MME and high-grade SIFK.
キーワード	medial meniscus posterior root tear subchondral insufficiency fracture bone marrow edema meniscus extrusion
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	121
終了ページ	127
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503439
Web of Science KeyUT	000792374900003

Pathological Complete Response Patients after Neoadjuvant Chemotherapy in Breast Cancer

JaLCDOI	10.18926/AMO/63403
フルテキストURL	76_2_105.pdf
著者	Takaoka, Megumi\| Ohsumi, Shozo\| Ikejiri, Haruka\| Shidahara, Tomohiro\| Miyoshi, Yuichiro\| Takahashi, Mina\| Takashima, Seiki\| Aogi, Kenjiro\|
抄録	Cases of breast cancer metastasis after achieving a pathological complete response (pCR) with neoadjuvant chemotherapy (NAC) are sometimes encountered in clinical practice. We investigated the prognostic factors for pCR in patients with breast cancer after NAC. This retrospective cohort study included patients with localized breast cancer who underwent NAC followed by surgery between 2004 and 2020 and achieved a pCR. The associations between clinical factors and distant metastasis-free survival rate were statistically analyzed. We analyzed data for 127 patients. Twelve patients (9.4%) had distant metastases, and seven (5.5%) died. For estrogen receptor (ER)-positive patients, the distant metastasis-free survival rate was 94.6% for both 5 and 8 years. In contrast, ER-negative patients had a distant metastasis-free survival rate of 87.6% and 85.4% for 5 and 8 years (p=0.094), respectively. In cT0-2 patients, the distant metastasis-free survival rate was 92.4% for 5 years and 90.5% for 8 years, whereas in cT3-4 patients, the distant metastasis-free survival rate was 83.5% for 5 years and 83.5% for 8 years (p=0.301). This study suggested that patients with ER-negative, pre-NAC cT3 or T4 breast cancer who had achieved a pCR after NAC tended to have a worse prognosis.
キーワード	breast carcinoma neoadjuvant therapy prognosis
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	105
終了ページ	111
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503437
Web of Science KeyUT	000792374900001