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JaLCDOI 10.18926/AMO/62775
フルテキストURL 75_5_625.pdf
著者 Iwamuro, Masaya| Yamasaki, Yasushi| Tanaka, Takehiro| Asada, Noboru| Matsuoka, Ken-ichi| Hiraoka, Sakiko| Kawahara, Yoshiro| Okada, Hiroyuki|
抄録 A 77-year-old Japanese woman who had been treated for follicular lymphoma for 8 years developed abdominal pain and intra-abdominal lymphadenopathies. Colonoscopy revealed an elevated lesion in the rectum, which presented as two humps with erosions. A diagnosis of histologic transformation of follicular lymphoma to diffuse large B-cell lymphoma was made by endoscopic biopsy. This case underscores the importance of endoscopy examinations and biopsy of newly emerged gastrointestinal lesions for the prompt diagnosis of histologic transformation, since salvage chemotherapy must be initiated quickly in such cases.
キーワード colorectal lymphoma follicular lymphoma diffuse large B-cell lymphoma histologic transformation
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2021-10
75巻
5号
出版者 Okayama University Medical School
開始ページ 625
終了ページ 629
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34703045
Web of Science KeyUT 000711561300001
NAID 120007166675
JaLCDOI 10.18926/AMO/62767
フルテキストURL 75_5_549.pdf
著者 Isooka, Nami| Miyazaki, Ikuko| Asanuma, Masato|
抄録 Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. The loss of nigrostriatal dopaminergic neurons produces its characteristic motor symptoms, but PD patients also have non-motor symptoms such as constipation and orthostatic hypotension. The pathological hallmark of PD is the presence of α-synuclein-containing Lewy bodies and neurites in the brain. However, the PD pathology is observed in not only the central nervous system (CNS) but also in parts of the peripheral nervous system such as the enteric nervous system (ENS). Since constipation is a typical prodromal non-motor symptom in PD, often preceding motor symptoms by 10-20 years, it has been hypothesized that PD pathology propagates from the ENS to the CNS via the vagal nerve. Discovery of pharmacological and other methods to halt this progression of neurodegeneration in PD has the potential to improve millions of lives. Astrocytes protect neurons in the CNS by secretion of neurotrophic and antioxidative factors. Similarly, astrocyte-like enteric glial cells (EGCs) are known to secrete neuroprotective factors in the ENS. In this article, we summarize the neuroprotective function of astrocytes and EGCs and discuss therapeutic strategies for the prevention of neurodegeneration in PD targeting neurotrophic and antioxidative molecules in glial cells.
キーワード Parkinson’s disease astrocyte enteric glial cell neurotrophic factor antioxidative molecule
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2021-10
75巻
5号
出版者 Okayama University Medical School
開始ページ 549
終了ページ 556
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34703037
Web of Science KeyUT 000711561600001
NAID 120007166678
フルテキストURL fulltext.pdf
著者 Kanzaki, Hiromitsu| Matsueda, Kazuhiro| Nakagawa, Masahiro| Inaba, Tomoki| Takatani, Masahiro| Takenaka, Ryuta| Yoshioka, Masao| Imagawa, Atsushi| Inoue, Masafumi| Suzuki, Seiyuu| Tomoda, Jun| Iwamuro, Masaya| Kawano, Seiji| Kawahara, Yoshiro| Tanaka, Takehiro| Okada, Hiroyuki|
キーワード duodenal neoplasms endoscopic mucosal resection natural history
発行日 2021-10-01
出版物タイトル Medicine
100巻
39号
出版者 Lippincott Williams & Wilkins
開始ページ e27382
ISSN 0025-7974
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 the Author(s).
論文のバージョン publisher
PubMed ID 34596158
DOI 10.1097/MD.0000000000027382
Web of Science KeyUT 000701020600039
関連URL isVersionOf https://doi.org/10.1097/MD.0000000000027382
フルテキストURL fulltext.pdf
著者 Ono, Sawako| Marunaka, Hidenori| Yanai, Hiroyuki| Kawai, Hotaka| Takabatake, Kiyofumi| Nishida, Kenji| Toji, Tomohiro| Nakano, Keisuke| Nagatsuka, Hitoshi| Yoshino, Tadashi|
キーワード Lymphoepithelial carcinoma oral cavity lateral tongue
発行日 2021-08-12
出版物タイトル reports
4巻
3号
出版者 MDPI
開始ページ 24
ISSN 2571-841X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 by the authors.
論文のバージョン publisher
DOI 10.3390/reports4030024
Web of Science KeyUT 000701728000001
関連URL isVersionOf https://doi.org/10.3390/reports4030024
フルテキストURL fulltext.pdf
著者 Mansour, Hager| Hassan, Ghmkin| Afify, Said M.| Yan, Ting| Seno, Akimasa| Seno, Masaharu|
キーワード metastasis cancer stem cells transplantation surgery
発行日 2020-08-21
出版物タイトル Methods and Protocols
3巻
3号
出版者 MDPI
開始ページ 60
ISSN 2409-9279
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by the authors.
論文のバージョン publisher
PubMed ID 32825540
DOI 10.3390/mps3030060
Web of Science KeyUT 000698975500015
関連URL isVersionOf https://doi.org/10.3390/mps3030060
フルテキストURL fulltext20211004-1.pdf
著者 Fukui, Yuko| Hayano, Satoru| Kawanabe, Noriaki| Wang, Ziyi| Shimada, Akira| Saito, Megumu K.| Asaka, Isao| Kamioka, Hiroshi|
キーワード iPS cell RPL5 cleft lip and palate chondrocyte Diamond-Blackfan Anemia
備考 This is an Accepted Manuscript of an article published by Wiley.
This is the peer reviewed version of the following article: [Fukui, Y, Hayano, S, Kawanabe, N, Wang, Z, Shimada, A, Saito, MK, et al. Investigation of the molecular causes underlying physical abnormalities in Diamond-Blackfan anemia patients with RPL5 haploinsufficiency. Pathology International. 2021; 1-11. https://doi.org/10.1111/pin.13168], which has been published in final form at [https://doi.org/10.1111/pin.13168]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-ArchivedVersions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wileyor by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked toWiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof bythird parties from platforms, services and websites other than Wiley Online Library must be prohibited.|
発行日 2021-9-29
出版物タイトル Pathology International
2021巻
出版者 Wiley
開始ページ 1
終了ページ 11
ISSN 1320-5463
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 Japanese Society of Pathology and John Wiley & Sons Australia, Ltd
論文のバージョン author
DOI 10.1111/pin.13168
関連URL isVersionOf https://doi.org/10.1111/pin.13168
フルテキストURL fulltext20210928-1.pdf
著者 Umeda, Yuzo| Mitsuhashi, Toshiharu| Kojima, Toru| Satoh, Daisuke| Sui, Kenta| Endo, Yoshikatsu| Inagaki, Masaru| Oishi, Masahiro| Yagi, Takahito| Fujiwara, Toshiyoshi|
キーワード intrahepatic cholangiocarcinoma lymph node excision multicenter study propensity score retrospective studies
備考 This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.|
発行日 2021-9-16
出版物タイトル Journal of Hepato-Biliary-Pancreatic Sciences
出版者 Wiley
開始ページ 1
終了ページ 13
ISSN 1868-6974
NCID AA12507209
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 The Authors. Journal of Hepato-Biliary-Pancreatic Sciences published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Hepato-Biliary-Pancreatic Surgery.
論文のバージョン publisher
PubMed ID 34473411
DOI 10.1002/jhbp.1038
Web of Science KeyUT 000696321700001
関連URL isVersionOf https://doi.org/10.1002/jhbp.1038
フルテキストURL fulltext.pdf
著者 Oda, Naohiro| Tabata, Masahiro| Uno, Masatoshi| Umeda, Yuzo| Kato, Hironari| Kubo, Toshio| Senoo, Satoru| Yagi, Takahito| Fujiwara, Toshiyoshi| Maeda, Yoshinobu| Kiura, Katsuyuki|
キーワード pancreas mucinous cystadenocarcinoma carboplatin paclitaxel
発行日 2021-09-15
出版物タイトル Internal Medicine
60巻
18号
出版者 The Japanese Society of Internal Medicine
開始ページ 2967
終了ページ 2971
ISSN 0918-2918
NCID AA10827774
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 The Japanese Society of Internal Medicine
論文のバージョン publisher
PubMed ID 33814494
DOI 10.2169/internalmedicine.6730-20
Web of Science KeyUT 000697279400013
関連URL isVersionOf https://doi.org/10.2169/internalmedicine.6730-20
フルテキストURL fulltext20210915.pdf
著者 Hyodo, Kiwamu|
備考 This is a post-peer-review, pre-copyedit version of an article published in Journal of General Plant Pathology. The final authenticated version is available online at: https://doi.org/10.1007/s10327-021-01022-9 This fulltext is available in Sep. 2022.|
発行日 2021-8-31
出版物タイトル Journal of General Plant Pathology
87巻
6号
出版者 Springer Science and Business Media LLC
開始ページ 415
終了ページ 417
ISSN 1345-2630
NCID AA11449093
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 Springer Nature Switzerland AG.
論文のバージョン author
DOI 10.1007/s10327-021-01022-9
関連URL isVersionOf https://doi.org/10.1007/s10327-021-01022-9
フルテキストURL fulltext.pdf
著者 Matsumoto, Kazuyuki| Kato, Hironari| Kitano, Masayuki| Hara, Kazuo| Kuwatani, Masaki| Ashida, Reiko| Takenaka, Mamoru| Yamazaki, Tatsuhiro| Sakurai, Jun| Yoshida, Michihiro| Okada, Hiroyuki|
キーワード gastroenterology endoscopy pancreatic disease
発行日 2021
出版物タイトル BMJ Open
11巻
7号
出版者 BMJ Publishing Group
開始ページ e046505
ISSN 2044-6055
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Author(s) (or their employer(s)) 2021.
論文のバージョン publisher
PubMed ID 34253667
DOI 10.1136/bmjopen-2020-046505
Web of Science KeyUT 000691612700018
関連URL isVersionOf https://doi.org/10.1136/bmjopen-2020-046505
JaLCDOI 10.18926/AMO/62407
フルテキストURL 75_4_529.pdf
著者 Inada, Ryo| Watanabe, Ayako| Toshima, Toshiaki| Katsura, Yuki| Sato, Takuji| Sui, Kenta| Oishi, Kazuyuki| Okabayashi, Takehiro| Ozaki, Kazuhide| Shibuya, Yuichi| Matsumoto, Manabu| Iwata, Jun|
抄録 A 67-year-old woman underwent polypectomy for a tumor at the descending colon. Pathologically, the tumor was diagnosed as adenocarcinoma with an invasion of 2000 μm. Computed tomography showed a swollen paracolic lymph node and a mass lesion in the presacral space. Magnetic resonance imaging revealed a multio-cular cystic lesion. On diagnosis of descending colon cancer and tailgut cyst, she underwent synchronous lapa-roscopic resection. Histopathologically, the colon cancer was diagnosed as pT1bN1M0, pStage IIIa. The pre-sacral cystic lesion was diagnosed as a nonmalignant tailgut cyst with negative surgical margin. The patient is currently doing well without recurrence at 28 months.
キーワード anterior approach laparoscopic resection tailgut cyst
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2021-08
75巻
4号
出版者 Okayama University Medical School
開始ページ 529
終了ページ 532
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34511622
Web of Science KeyUT 000696755800001
NAID 120007146033
JaLCDOI 10.18926/AMO/62406
フルテキストURL 75_4_523.pdf
著者 Yamashita, Mampei| Kuroki, Tamotsu| Matsuoka, Yuki| Miura, Shiro| Hamada, Takashi| Hirayama, Takanori| Yoneda, Akira| Tokunaga, Takayuki| Yamanouchi, Kosho| Takeshita, Hiroaki| Maeda, Shigeto|
抄録 Acute mesenteric ischemia (AMI) is often caused by superior mesenteric artery (SMA) embolization. We report a rare case of synchronous celiac axis and SMA embolization in an elderly woman with initially mild abdominal pain. Ultimately, a second contrast-enhanced computed tomography revealed extensive necrosis from the stomach to the transverse colon together with liver ischemia due to hours of occlusion. Multiorgan failure made palliation the only option, and she died the following evening. Autopsy revealed a fragile atherosclerosis-asso-ciated thrombus. Careful examination and repeat diagnostic tests should be performed in patients with mild abdominal symptoms at risk for AMI.
キーワード atherosclerosis celiac axis mesenteric ischemia superior mesenteric artery thromboembolism
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2021-08
75巻
4号
出版者 Okayama University Medical School
開始ページ 523
終了ページ 527
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34511621
Web of Science KeyUT 000709282300007
NAID 120007146032
JaLCDOI 10.18926/AMO/62405
フルテキストURL 75_4_517.pdf
著者 Ochi, Masahiko| Iida, Atsuyoshi| Takahashi, Yuka| Tanaka, Masamichi| Saito, Hironori| Naito, Hiromichi| Mikane, Takeshi| Fuke, Soichiro|
抄録 Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically mediated cardiomyopathy charac-terized by progressive myocardial loss of the right ventricle and its replacement by fibrofatty tissue, causing dyskinesia, aneurysm, and/or arrhythmia. The prevalence of ARVC is estimated to be 1 in 2,000-5,000, with the condition accounting for up to 20% of sudden cardiac deaths in individuals < 35 years old. This report describes the case of 61-year-old Japanese who was diagnosed with ARVC after cardiac arrest (CA) and successful resusci-tation. After the sudden CA, the restoration of spontaneous circulation was achieved with appropriate resusci-tation, followed by the introduction of target temperature management in the intensive care unit. He was diag-nosed with ARVC based on angiography and histology results. An ICD (implantable cardioverter-defibrillator) was implanted, and he was discharged without neurological sequelae 1 month post-CA. ARVC is an important cause of sudden CA, and successfully resuscitated patients with right ventricular dilation should undergo testing to rule out ARVC.
キーワード inverted T-wave right ventricular dilatation sudden cardiac arrest sudden cardiac death
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2021-08
75巻
4号
出版者 Okayama University Medical School
開始ページ 517
終了ページ 521
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34511620
Web of Science KeyUT 000709282300006
NAID 120007146031
JaLCDOI 10.18926/AMO/62399
フルテキストURL 75_4_471.pdf
著者 Iwamuro, Masaya| Toyokawa, Tatsuya| Matsueda, Kazuhiro| Hori, Shinichiro| Yoshioka, Masao| Moritou, Yuki| Tanaka, Takehiro| Mizuno, Motowo| Okada, Hiroyuki|
抄録 The characteristics of gastric polyps in patients with Peutz-Jeghers (PJ) syndrome (PJS) have not been fully investigated. The objective of this study was to reveal the endoscopic and pathologic findings of gastric polyps in patients with PJS. We reviewed 11 patients with PJS treated at 6 institutions, and summarized the endo-scopic and pathologic features of their gastric polyps. The polyps were mainly classified into 2 types: (i) soli-tary or sporadic polyps > 5 mm, reddish in color with a sessile or semi-pedunculated morphology (n = 9); and (ii) multiple sessile polyps ≤ 5 mm with the same color tone as the peripheral mucosa (n = 9). Patients who underwent endoscopic mucosal resection for polyps > 5 mm were diagnosed with PJ polyps (n = 2), whereas those who underwent biopsy were diagnosed with hyperplastic polyps. Polyps ≤ 5 mm were pathologically diagnosed as fundic gland polyps or hyperplastic polyps. This study revealed that patients with PJS present with 2 types of polyps in the stomach. Endoscopic mucosal resection of polyps > 5 mm seems necessary for the pathologic diagnosis of PJ polyps.
キーワード Peutz-Jeghers syndrome esophagogastroduodenoscopy gastric polyps
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-08
75巻
4号
出版者 Okayama University Medical School
開始ページ 471
終了ページ 477
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34511614
Web of Science KeyUT 000701717000001
NAID 120007146042
JaLCDOI 10.18926/AMO/62397
フルテキストURL 75_4_455.pdf
著者 Muraoka, Sosuke| Yamane, Kentaro| Misawa, Haruo| Takigawa, Tomoyuki| Tetsunaga, Tomoko| Oda, Yoshiaki| Nakanishi, Kazuo| Ozaki, Toshifumi| Tanaka, Takehiro|
抄録 The intraoperative pathological diagnosis (IPD) plays an important role in determining the optimal surgical treatment for spinal cord tumors. The final pathological diagnosis (FPD) is sometimes different from the IPD. Here, we sought to identify the accuracy of the IPD of spinal cord tumors compared to the FPD. We retrospec-tively analyzed the cases of 108 patients with spinal cord tumors treated surgically in our institute; the IPD, FPD, mismatched cases, and concordance rate between the IPD and FPD were investigated. Five cases involved a mismatch between the IPD and FPD. The overall concordance rate was 95.4%, with 90.9% for extra-dural lesions, 98.5% for intradural extramedullary lesions, 84.2% for intramedullary lesions, and 100% for dumbbell-type tumors. The concordance rate of intramedullary lesions tended to be lower than that of other lesions (p = 0.096). A lower concordance rate was revealed for intramedullary lesions compared to the other lesions. Despite the IPD clearly remaining a valuable tool during operative procedures, surgeons should recog-nize the limitations of IPDs and make comprehensive decisions about surgical treatments.
キーワード spinal cord tumor intraoperative pathological diagnosis final pathological diagnosis concordance rate
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-08
75巻
4号
出版者 Okayama University Medical School
開始ページ 455
終了ページ 460
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34511612
Web of Science KeyUT 000697944600007
NAID 120007146040
JaLCDOI 10.18926/AMO/62396
フルテキストURL 75_4_447.pdf
著者 Kono, Reika| Hamasaki, Ichiro| Kishimoto, Fumiko| Ohtuski, Hiroshi| Shibata, Kiyo| Morizane, Yuki| Shiraga, Fumio|
抄録 In high myopia, eye dislocation due to increased globe volume or tight orbital volume causes acquired esotro-pia. GOR (globe/orbit volume ratio), an indicator of the degree of progression of this pathology, was investi-gated the relationships among easily obtained clinical parameters. In this retrospective study, 20 eyes from 10 acquired esotropia patients with high myopia but without abduction limitations were examined. The mean age of the patients was 63.7 ± 8.2 years (mean ± standard deviation). Volumes were measured on the three-dimen-sional fast imaging employing steady-state acquisition magnetic resonance imaging images using the vol-ume-measurement function. Correlations between GOR and the displacement angle of the globe (DA), axial length (AL), and equatorial diameter (ED) were investigated. Mean DA, AL, ED, and GOR values were 107.5 ± 8.5°, 28.86 ± 1.92 mm, 25.00 ± 1.16 mm, and 0.36 ± 0.05, respectively. Only AL was correlated with GOR (p < 0.0001, R2 = 0.6649); DA (p = 0.30, R2 = 0.0633) and ED (p = 0.91, R2 = 0.0008) were not. AL was the only clinically available parameter to indicate globe/orbit volume imbalances in acquired esotropia with high myopia but without abduction limitation. AL may be important for the clinical assessment of the progression of this pathology.
キーワード acquired esotropia high myopia (high myopes) globe volume magnetic resonance imaging limitation of abduction
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-08
75巻
4号
出版者 Okayama University Medical School
開始ページ 447
終了ページ 453
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34511611
Web of Science KeyUT 000697944600006
NAID 120007146039
フルテキストURL fulltext.pdf
著者 Yamamoto, Norio| Sukegawa, Shintaro| Yamashita, Kazutaka| Manabe, Masaki| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Ozaki, Toshifumi| Kawasaki, Keisuke| Nagatsuka, Hitoshi| Furuki, Yoshihiko| Yorifuji, Takashi|
キーワード patient variables osteoporosis deep learning convolutional neural network ensemble model effect size
発行日 2021-08-20
出版物タイトル Medicina-Lithuania
57巻
8号
出版者 MDPI
開始ページ 846
ISSN 1010-660X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 by the authors.
論文のバージョン publisher
PubMed ID 34441052
DOI 10.3390/medicina57080846
Web of Science KeyUT 000689547600001
関連URL isVersionOf https://doi.org/10.3390/medicina57080846
フルテキストURL fulltext.pdf
著者 Obata, Kyoichi| Okui, Tatsuo| Ono, Sawako| Umemori, Koki| Ryumon, Shoji| Ono, Kisho| Yao, Mayumi| Yoshioka, Norie| Ibaragi, Soichiro| Sasaki, Akira|
キーワード methotrexate lymphoproliferative disorders Epstein-Barr virus mucocutaneous ulcer rheumatoid arthritis
発行日 2021-07-30
出版物タイトル Diagnostics
11巻
8号
出版者 MDPI
開始ページ 1375
ISSN 2075-4418
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 by the authors.
論文のバージョン publisher
PubMed ID 34441310
DOI 10.3390/diagnostics11081375
Web of Science KeyUT 000688919100001
関連URL isVersionOf https://doi.org/10.3390/diagnostics11081375
フルテキストURL fulltext.pdf
著者 Asanuma, Masato| Miyazaki, Ikuko|
キーワード glutathione neuroprotection parkinsonism astrocyte region specificity striatum mesencephalon oxidative stress Nrf2 metallothionein serotonin 5-HT1A receptor
発行日 2021-08-13
出版物タイトル International Journal of Molecular Sciences
22巻
16号
出版者 MDPI
開始ページ 8689
ISSN 1422-0067
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 by the authors.
論文のバージョン publisher
PubMed ID 34445395
DOI 10.3390/ijms22168689
Web of Science KeyUT 000690633200001
関連URL isVersionOf https://doi.org/10.3390/ijms22168689
JaLCDOI 10.18926/AMO/62378
フルテキストURL 75_4_403.pdf
著者 Matoba, Ryo| Morizane, Yuki|
抄録 Epiretinal membrane (ERM) is a common retinal disease characterized by cellular proliferation and metaplasia that lead to the formation of a pathological fibrocellular membrane immediately superjacent to the inner retinal surface. The vast majority of ERMs are considered idiopathic. However, ERM formation can result from various primary intraocular diseases, including retinal breaks and detachment, retinal vascular diseases, and vitreoretinal inflammatory conditions. Although ERMs are generally asymptomatic or cause mild metamorphopsia and/or a modest decrease in visual acuity, some can cause severe macular distortion and macular edema, resulting in significantly impaired function. Surgical removal of ERM is the only treatment, and improvements in vitrectomy systems have enabled less invasive treatment. However, there are currently no standardized criteria for ERM surgery, and the indications for surgery are determined from the patient’s subjective symptoms. Another problem with ERM surgery is that not all patients show satisfactory postoperative recovery of visual function. Thus, further research is needed to determine the criteria for ERM surgery and methods to improve the postoperative prognosis.
キーワード epiretinal membrane vitrectomy optical coherence tomography internal limiting membrane lamellar macular hole
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2021-08
75巻
4号
出版者 Okayama University Medical School
開始ページ 403
終了ページ 413
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34511606
Web of Science KeyUT 000697944600001
NAID 120007146059