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Author Kinuta, Minako| Hisamatsu, Takashi| Taniguchi, Kaori| Fukuda, Mari| Nakahata, Noriko| Kanda, Hideyuki|
Note The version of record of this article, first published in Journal of Human Hypertension, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41371-025-01014-8|
Published Date 2025-04-03
Publication Title Journal of Human Hypertension
Publisher Springer Science and Business Media LLC
ISSN 1476-5527
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40181092
DOI 10.1038/s41371-025-01014-8
Web of Science KeyUT 001458976500001
Related Url isVersionOf https://doi.org/10.1038/s41371-025-01014-8
FullText URL fulltext.pdf
Author Ohue, Takashi| Ohue, Yuka| Harada, Hiroe|
Keywords COVID-19 clinical practice newly graduated nurses nursing practice skills longitudinal study
Published Date 2025
Publication Title SAGE Open Nursing
Volume volume11
Publisher SAGE Publications
ISSN 2377-9608
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40078440
DOI 10.1177/23779608251323836
Web of Science KeyUT 001442147100001
Related Url isVersionOf https://doi.org/10.1177/23779608251323836
JaLCDOI 10.18926/AMO/68361
FullText URL 79_1_047.pdf
Author Kojima, Kazunori| Ujikawa, Takuya| Ono, Toshiro|
Abstract We assessed the immediate effects of a home-based rehabilitation (HBR) program on the balance performance and toe-grip strength of 29 older adults (mean±SD age of 75.1±9.9; 16 males, 13 females) who were participating in HBR services provided by Japan’s nursing care insurance system. Their toe-grip strength and balance performance were measured before and after the HBR program. The subjects’ toe-grip strength was significantly improved after the treatment. The subjects who had had a stroke showed a significant improvement after HBR. Contrarily, no significant difference was observed in the subjects’ functional reach results or their one-leg standing time. These results indicate that the exercise regimen provided in the HBR program led to increased excitability of motor units and immediately enhanced the subjects’ toe-grip strength.
Keywords home-based rehabilitation toe-grip strength balance performance
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-02
Volume volume79
Issue issue1
Publisher Okayama University Medical School
Start Page 47
End Page 50
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 40012159
Web of Science KeyUT 001440463800006
FullText URL fulltext.pdf
Author Nakamura, Naoko| Mitsuhashi, Toshiharu| Nakashima, Yasuko| Matsumoto, Naomi| Yorifuji, Takashi|
Keywords community health planning diagnostic screening programmes home visits postpartum depression postnatal care quasi-experimental study
Published Date 2023-07-19
Publication Title Family Practice
Publisher Oxford University Press (OUP)
Start Page cmad074
ISSN 1460-2229
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37467366
DOI 10.1093/fampra/cmad074
Web of Science KeyUT 001030159100001
Related Url isVersionOf https://doi.org/10.1093/fampra/cmad074
JaLCDOI 10.18926/AMO/67664
FullText URL 78_5_401.pdf
Author Toyota, Yusuke| Uda, Kazuhiro| Shirabe, Komei| Moriwake, Tadashi|
Abstract Severe febrile thrombocytopenia syndrome (SFTS) is a tick-borne infectious disease that is endemic in parts of eastern Asia. Few pediatric cases have been reported. We describe a case of SFTS in a seven-year-old girl who presented with prolonged fever and gastrointestinal symptoms. Leukopenia and thrombocytopenia on hematology, and a history of outdoor activity led us to diagnose SFTS, although the patient had no tick bite marks. We also review the literature and discuss the characteristics of pediatric SFTS. Physicians should consider SFTS in the differential diagnosis of fever with thrombocytopenia in children living in endemic areas.
Keywords child tick-borne disease severe febrile thrombocytopenia syndrome zoonoses
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-10
Volume volume78
Issue issue5
Publisher Okayama University Medical School
Start Page 401
End Page 405
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39467658
JaLCDOI 10.18926/AMO/67662
FullText URL 78_5_377.pdf
Author Hirano, Yuichi| Nouso, Kazuhiro| Kariyama, Kazuya| Hiraoka, Atsushi| Shiota, Shohei| Wakuta, Akiko| Yasuda, Satoshi| Toyoda, Hidenori| Tsuji, Kunihiko| Hatanaka, Takeshi| Kakizaki, Satoru| Naganuma, Atsushi| Tada, Toshifumi| Itobayashi, Ei| Ishikawa, Toru| Shimada, Noritomo| Takaguchi, Koichi| Tsutsui, Akemi| Nagano, Takuya| Imai, Michitaka| Nakamura, Shinichiro| Kumada, Takashi| Real-Life Practice Experts for HCC (RELPEC) Study Group in Japan|
Abstract We previously found that “albumin grade”, formerly called the “ALBS grade,” demonstrated significant capability for prognostic stratification in hepatocellular carcinoma (HCC) patients treated with lenvatinib. The purpose of the present study was to compare the performance of the albumin grade with that of the modified albumin-bilirubin (mALBI) grade in predicting overall survival of HCC patients with different BCLC stages and treatment types. We enrolled 7,645 Japanese patients newly diagnosed with HCC using the Akaike information criteria (AIC), likelihood ratio, and C-index in different Barcelona Clinic Liver Cancer (BCLC) stages and treatments. The albumin grade showed similar and slightly better performance than the mALBI grade for BCLC stage 0 and A and especially for patients who underwent curative surgery and ablation. In patients treated with transcatheter arterial chemoembolization, molecular targeted agents, and the best supportive care, the mALBI grade had better performance than the albumin grade. However, the differences of the indices were very small in all scenarios. Overall, the albumin grade was comparable in efficacy to the mALBI grade, showing particular benefit for patients with early-stage HCC.
Keywords albumin grade hepatocellular carcinoma modified albumin-bilirubin grade
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-10
Volume volume78
Issue issue5
Publisher Okayama University Medical School
Start Page 377
End Page 386
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39467656
Web of Science KeyUT 001343346400004
JaLCDOI 10.18926/AMO/67547
FullText URL 78_4_313.pdf
Author Eto, Eriko| Maki, Jota| Yamashita, Noriyuki| Hasegawa, Toru| Suemori, Ayano| Nakato, Hikari| Oba, Hikaru| Mitoma, Tomohiro| Mishima, Sakurako| Kirino, Satoe| Ohira, Akiko| Masuyama, Hisashi|
Abstract During the coronavirus pandemic, face-to-face simulation education became impossible. Therefore, we aimed to develop remote-access simulation education with a sense of realism through Information and Communication Technology (ICT) using a perinatal whole-body management and delivery simulator. In September 2021, we administered a multi-center simultaneous remote simulation based on our developed model. Ten universities in the Chugoku–Shikoku region were connected via a web-conferencing system to a live broadcast of a virtual vaginal birth in which a fictional hospitalized pregnant woman experienced accelerated labor and gave birth through vacuum delivery for fetal distress. A Video on Demand (VOD) was made beforehand using a new simulator that allowed for a visual understanding of the process of the inter-vaginal examination. We provided a participatory program that enhanced the sense of realism by combining VOD and real-time lectures on each scenario, with two-way communication between participants and trainee doctors using a chat function. Most participants answered “satisfied” or “very satisfied” with the content, level of difficulty, and level of understanding. From November 2021, we have used the videos of all processes in face-to-face classes. Our construction of a high-flexibility education system using remote simulation in the field of obstetrics and gynecology, especially in the vaginal delivery module, is unique, creative, and sustainable.
Keywords remote simulator education perinatal simulator information and communication technology high-flexibility education
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-08
Volume volume78
Issue issue4
Publisher Okayama University Medical School
Start Page 313
End Page 322
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39198985
Web of Science KeyUT 001310576400002
FullText URL fulltext.pdf
Author Yumoto, Tetsuya| Hongo, Takashi| Obara, Takafumi| Ageta, Kohei| Aokage, Toshiyuki| Tsukahara, Kohei| Nakao, Atsunori| Naito, Hiromichi|
Keywords clinical conference end-of-life care ICU rounds multidisciplinary team meetings
Published Date 2024-07-24
Publication Title Journal of Clinical Medicine
Volume volume13
Issue issue15
Publisher MDPI
Start Page 4324
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 39124591
DOI 10.3390/jcm13154324
Web of Science KeyUT 001287177900001
Related Url isVersionOf https://doi.org/10.3390/jcm13154324
FullText URL fulltext.pdf
Author Tokumoto, Kana| Mino, Takuya| Tosa, Ikue| Omori, Ko| Yamamoto, Michiyo| Takaoka, Kazuki| Maekawa, Kenji| Kuboki, Takuo| Kishimoto, Hiromitsu|
Keywords Parkinson's disease Older people Implant overdenture Nursing homes Implant-related troubles Peri-implantitis
Note The version of record of this article, first published in International Journal of Implant Dentistry, is available online at Publisher’s website: http://dx.doi.org/10.1186/s40729-024-00557-8|
Published Date 2024-07-29
Publication Title International Journal of Implant Dentistry
Volume volume10
Issue issue1
Publisher Springer
Start Page 37
ISSN 2198-4034
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 39073725
DOI 10.1186/s40729-024-00557-8
Web of Science KeyUT 001279622000001
Related Url isVersionOf https://doi.org/10.1186/s40729-024-00557-8
JaLCDOI 10.18926/AMO/67199
FullText URL 78_3_245.pdf
Author Akagawa, Manabu| Saito, Hidetomo| Takahashi, Yasuhiro| Iwamoto, Yosuke| Iida, Junpei| Yoshikawa, Takayuki| Abe, Toshiki| Saito, Kimio| Kijima, Hiroaki| Kasukawa, Yuji| Hongo, Michio| Miyakoshi, Naohisa|
Abstract Although several studies have suggested a possible association between sarcopenia and knee osteoarthritis (OA) in the elderly, there remains no definitive evidence. Recently, however, the serum creatinine/cystatin C ratio (sarcopenia index: SI) was reported to correlate with skeletal muscle mass. The present retrospective study therefore investigated the impact of reduced skeletal muscle mass on advanced knee OA using SI. In 55 individuals scheduled for knee osteotomy or knee arthroplasty, correlations between SI and patient-reported outcomes such as the Knee Society Score (KSS), Knee Injury and Osteoarthritis Outcome Score (KOOS), and Oxford Knee Score (OKS) were explored. Significant associations were found between SI and the KSS functional activity score (β=0.37; p=0.022), KOOS subscale for activities of daily living (β=0.42; p=0.0096), and OKS (β=0.42; p=0.0095). This study underscores the role of reduced muscle mass in functional outcomes and introduces SI as a valuable marker for assessing muscle loss in knee OA patients.
Keywords knee osteoarthritis sarcopenia index reduced muscle mass activities of daily living functional activity
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-06
Volume volume78
Issue issue3
Publisher Okayama University Medical School
Start Page 245
End Page 250
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38902212
Web of Science KeyUT 001267351000005
JaLCDOI 10.18926/AMO/66926
FullText URL 78_2_171.pdf
Author Kuramoto, Aya| Saito, Shinya| Watanabe, Kumi|
Abstract We investigated (i) the relationships among internalized stigma (IS), sense of coherence (SOC), and the personal recovery (PR) of persons with schizophrenia living in the community, and (ii) how to improve the support for these individuals. A questionnaire survey on IS, SOC, and PR was sent by mail to 270 persons with schizophrenia living in the community who were using psychiatric daycare services, of whom 149 responded and 140 were included in the analysis. We established a hypothetical model in which IS influences PR, and SOC influences IS and PR, and we used structural equation modeling to examine the relationships among these concepts. The goodness of fit was acceptable. Our findings suggest that rather than directly promoting PR, SOC promotes PR by mitigating the impact of IS. It is important for nurses/supporters to support individuals with schizophrenia living in the community so that they have opportunities to reflect on their own experiences through their activities and to share their experiences with peers. Nurses/supporters themselves should also reflect on their own support needs. Our findings suggest that this will lead to a reduction of IS and the improvement of SOC, which will in turn promote personal recovery.
Keywords schizophrenia internalized stigma sense of coherence personal recovery community
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 171
End Page 184
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688835
Web of Science KeyUT 001229151800009
JaLCDOI 10.18926/AMO/66671
FullText URL 78_1_053.pdf
Author Ichikawa, Yukiko| Ogino, Tetsuya|
Abstract Ice bags are frequently used in medical care settings for pain relief, comfort, and in some cases, whole-body cooling. This study quantifies heat energy transfer capacity of ice bags and evaluates their cooling effects on body temperature. Forty-eight healthy adults in their 20s were recruited. An ice bag wrapped in two layers of dry towel was applied to the forehead, neck, or palm of each participant for 10 min. The skin surface temperature, heat flow, and core temperature were recorded during the cooling and non-cooling periods, with energy transfer calculated by integrating heat flow over time. Over the non-cooling period, 31.4-53.6 kJ·m-2 of energy was dissipated over 10 min, whereas during the cooling period, the range increased to 180.0-218.7 kJ·m-2 over 10 min. Skin surface temperature decreased by 3.2-5.7°C, whereas core temperature was unchanged. Ice bag use augmented energy transfer by about 150-180 kJ·m-2 over 10 min, but this was insufficient for rapid whole body cooling due to the small skin-surface area in contact with the ice bag. The measured energy transfer indicated that topical ice bag application absorbs insufficient energy to affect core temperature. Quantitative assessment of energy transfer was shown to inform the safe and appropriate use of thermotherapy.
Keywords cold compress fever hyperthermia thermal conductivity thermoregulation
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-02
Volume volume78
Issue issue1
Publisher Okayama University Medical School
Start Page 53
End Page 61
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38419315
Web of Science KeyUT 001203658200009
FullText URL fulltext.pdf
Author Yumoto, Tetsuya| Kuribara, Tomoki| Yamada, Kohei| Sato, Takehito| Koba, Shigeru| Tetsuhara, Kenichi| Kashiura, Masahiro| Sakuraya, Masaaki|
Keywords capillary refill timecarbon dioxide gapcentral venous oxygen saturationlactatenetwork meta-analysissepsisseptic shock
Published Date 2023-12-26
Publication Title Acute Medicine and Surgery
Volume volume10
Issue issue1
Publisher Wiley
Start Page e914
ISSN 2052-8817
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 38148753
DOI 10.1002/ams2.914
Web of Science KeyUT 001135268300001
Related Url isVersionOf https://doi.org/10.1002/ams2.914
FullText URL fulltext.pdf
Author Tanabe, Ryo| Hongo, Takashi| Obara, Takafumi| Nojima, Tsuyoshi| Nakao, Atsunori| Elmer, Jonathan| Naito, Hiromichi| Yumoto, Tetsuya|
Keywords Do not attempt resuscitation Out-of-hospital cardiac arrest Emergency department Clinicians Slow code Stress
Published Date 2023-12
Publication Title Resuscitation Plus
Volume volume16
Publisher Elsevier
Start Page 100507
ISSN 2666-5204
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Author(s).
File Version publisher
PubMed ID 38026140
DOI 10.1016/j.resplu.2023.100507
Web of Science KeyUT 001112320800001
Related Url isVersionOf https://doi.org/10.1016/j.resplu.2023.100507
JaLCDOI 10.18926/AMO/66151
FullText URL 77_6_595.pdf
Author Bando, Takashi| Chuma, Masayuki| Hamano, Hirofumi| Niimura, Takahiro| Okada, Naoto| Kondo, Masateru| Izumi, Yuki| Ishida, Shunsuke| Yoshioka, Toshihiko| Asada, Mizuho| Zamami, Yoshito| Takechi, Kenshi| Goda, Mitsuhiro| Miyata, Koji| Yagi, Kenta| Izawa-Ishizawa, Yuki| Azuma, Momoyo| Yanagawa, Hiroaki| Tasaki, Yoshikazu| Ishizawa, Keisuke|
Abstract There is a growing concern about the relationship between vancomycin-associated nephrotoxicity (VAN) and concomitant use of nephrotoxins. We examined this relationship by combined retrospective analyses of two real-world databases. Initially, the FDA Adverse Event Reporting System (FAERS) was analyzed for the effects of concomitant use of one or more nephrotoxins on VAN and the types of combinations of nephrotoxins that exacerbate VAN. Next, electronic medical records (EMRs) of patients who received vancomycin (VCM) at Tokushima University Hospital between January 2006 and March 2019 were examined to confirm the FAERS analysis. An elevated reporting odds ratio (ROR) was observed with increases in the number of nephrotoxins administered (VCM + one nephrotoxin, adjusted ROR (95% confidence interval [CI]) 1.67 [1.51-1.85]; VCM + ≥2 nephrotoxins, adjusted ROR [95% CI] 1.54 [1.37-1.73]) in FAERS. EMRs analysis showed that the number of nephrotoxins was associated with higher incidences of VAN [odds ratio: 1.99; 95% CI: 1.42-2.78]. Overall, concomitant use of nephrotoxins was associated with an increased incidence of VAN, especially when at least one of those nephrotoxins was a renal hypoperfusion medication (furosemide, non-steroidal anti-inflammatory drugs, and vasopressors). The concomitant use of multiple nephrotoxins, especially including renal hypoperfusion medication, should be avoided to prevent VAN.
Keywords vancomycin-associated nephrotoxicity polypharmacy nephrotoxin spontaneous adverse event reporting database electronic medical records
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 595
End Page 605
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145933
Web of Science KeyUT 001164631200004
JaLCDOI 10.18926/AMO/66149
FullText URL 77_6_577.pdf
Author Liu, Siyu| Athurupana, Rukmali| Han, Hongmei| Yang, Titi| Nakatsuka, Mikiya|
Abstract Bereavement care is conducted to meet the emotional needs of grieving couples who are devastated by the experience of a miscarriage or stillbirth. From January to April 2022, we distributed a questionnaire that assessed the knowledge and attitudes of Japanese nursing staff (nurses and midwives) in Japan’s Chugoku-Shikoku region toward bereavement care for couples with miscarriage/stillbirth. The 370 survey respondents’ answers revealed that the nursing staff’s knowledge regarding recurrent pregnancy loss and subsequent bereavement care was insufficient. About 41.1% and 64.1% of the respondents had received school and on-the-job education in bereavement care, respectively, and 79.2% expressed willingness to provide such care. Our analyses revealed that the following factors were associated with the nursing staff’s knowledge level: parent status, age, reproductive history, midwifery license, work experience and environment, and on-the-job education. The following were correlated with the staff’s willingness to provide bereavement care: work environment, midwifery license, bereavement care knowledge, and on-the-job education. Together our findings indicate that education plays a significant role in equipping caregivers to provide effective bereavement care for couples who have experienced a miscarriage or stillbirth.
Keywords midwife nurse miscarriage bereavement knowledge
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 577
End Page 587
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145931
Web of Science KeyUT 001164631200002
JaLCDOI 10.18926/AMO/65970
FullText URL 77_5_479.pdf
Author Murata, Akiko| Matsumoto, Naomi| Miyaji, Chikara| Takao, Soshi| Yorifuji, Takashi|
Abstract For decades, the notion has persisted in developed countries that exclusive care by the mothers is best for the development of children up to 3 years of age. To examine the veracity of this “myth of the first three years” in Japan, we examined the effects of childcare facility use for children younger than 3 years on their development using the cohorts of the Longitudinal Survey of Newborns in the 21st Century conducted in Japan. Of the 47,015 respondents to the survey, we studied the children of 5,508 mothers with university/professional education to evaluate the relationships between primary early (< 2.5 years) childcare providers during weekday daytime hours and specific development indices for the ages of 2.5, 5.5, and 8 years. At the age of 2.5 and 5.5 years, children attending childcare facilities were judged as having more advanced developmental behaviors by their parents, such as being able to compose a two-word sentence (adjusted odds ratio [aOR]: 0.22) or to express emotions (aOR: 0.81), compared with those cared for by mothers. However, at the age of 8 years, children who attended childcare facilities as infants < 2.5 years showed more aggressive behavior in interrupting people (aOR: 1.20) and causing disturbances in public (aOR: 1.26) than those cared for by mothers (after adjustment for numerous child and parental factors). Although these results are generally consistent with previous studies, issues potentially involved with problem behavior such as quality of childcare require further investigation, as does the case of children of mothers with more modest educational attainment.
Keywords “myth of the first three years” childcare child development problem behavior educational attainment
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 479
End Page 490
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899259
Web of Science KeyUT 001108661600005
JaLCDOI 10.18926/AMO/65751
FullText URL 77_4_407.pdf
Author Hotta, Kensuke| Kobayashi, Takaomi|
Abstract This study aimed to investigate the usefulness of force-controlled pelvic stress radiographs in the evaluation and treatment of fragility fractures of the pelvis (FFP) using a functional treatment strategy. We conducted a retrospective study of 55 geriatric patients with FFP who underwent pelvic stress radiographs on admission. The differences in the sacral width, pelvic ring width, and medial femoral head width between the radiographs with and without the Sam Sling II M size were defined as Δ sacral width, Δ pelvic ring width, and Δ medial femoral head width, respectively. We used Pearson’s correlation test to assess the relationship between the degree of radiographic instability and the Johns Hopkins highest level of mobility scale (JH-HLM) at 10-days postadmission. Conventional receiver-operating-characteristic curve analysis was used to identify cases requiring surgery using the best cutoff value for radiographic instability. The JH-HLM was significantly correlated with Δ sacral width (r=−0.401, p=0.017), but not with Δ pelvic ring width (r=−0.298, p=0.080) nor with Δ medial femoral head width (r= −0.261, p=0.128). The best cutoff value of Δ sacral width in identifying surgical cases was 10.7 mm (sensitivity 75.0%, specificity 98.0%). Force-controlled pelvic stress radiographs could be helpful in assessing the need for surgery on admission.
Keywords fragility fracture of the pelvis functional treatment strategy Sam Sling stress radiograph Johns Hopkins highest level of mobility scale
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 407
End Page 414
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635141
Web of Science KeyUT 001163659800001
JaLCDOI 10.18926/AMO/65741
FullText URL 77_4_359.pdf
Author Koshida, Tomohiro| Maruta, Toyoaki| Tanaka, Nobuhiko| Hidaka, Kotaro| Kurogi, Mio| Nemoto, Takayuki| Yanagita, Toshihiko| Takeya, Ryu| Tsuneyoshi, Isao|
Abstract Pulsed radiofrequency (PRF) is a safe method of treating neuropathic pain by generating intermittent electric fields at the needle tip. Resiniferatoxin (RTX) is an ultrapotent agonist of transient receptor potential vanilloid subtype-1 (TRPV1) receptors. We investigated the mechanism of PRF using a rat model of RTX-induced neuropathic pain. After administering RTX intraperitoneally, PRF was applied to the right sciatic nerve. We observed the changes in TRPV1, calcitonin gene-related peptide (CGRP), and brain-derived neurotrophic factor (BDNF) in the dorsal root ganglia by western blotting. Expressions of TRPV1 and CGRP were significantly lower in the contralateral (RTX-treated, PRF-untreated) tissue than in control rats (p<0.0001 and p<0.0001, respectively) and the ipsilateral tissues (p<0.0001 and p<0.0001, respectively). BDNF levels were significantly higher in the contralateral tissues than in the control rats (p<0.0001) and the ipsilateral tissues (p<0.0001). These results suggest that, while TRPV1 and CGRP are decreased by RTX-induced neuronal damage, increased BDNF levels result in pain development. PRF may promote recovery from neuronal damage with concomitant restoration of TRPV1 and CGRP, and exert its analgesic effect by reversing BDNF increase. Further research is required to understand the role of TRPV1 and CGRP restoration in improving mechanical allodynia.
Keywords pulsed radiofrequency resiniferatoxin transient receptor potential vanilloid subtype-1 (TRPV1) calcitonin gene-related peptide (CGRP) brain-derived neurotrophic factor (BDNF)
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 359
End Page 364
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635135
Web of Science KeyUT 001163659800011
FullText URL fulltext20230911-02.pdf
Author Ninomiya, Kiichiro| Inoue, Daisuke| Sugimoto, Ken| Tanaka, Chie| Murofushi, Keiko| Okuyama, Toru| Watanuki, Shigeaki| Imamura, Chiyo K.| Sakai, Daisuke| Sakurai, Naomi| Watanabe, Kiyotaka| Tamura, Kazuo| Saeki, Toshiaki| Ishiguro, Hiroshi|
Keywords Comprehensive geriatric assessment Guideline Systematic review
Published Date 2023-06-11
Publication Title Journal of Geriatric Oncology
Volume volume14
Issue issue5
Publisher Elsevier
Start Page 101485
ISSN 18794068
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 37062639
DOI 10.1016/j.jgo.2023.101485
Web of Science KeyUT 001049053400001
Related Url isVersionOf https://doi.org/10.1016/j.jgo.2023.101485