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Author Hirami, Yuki| Nishimura, Midori Filiz| Urata, Tomohiro| Morimoto, Michiko| Maekawa, Yukina| Yoshino, Tadashi| Nishimura, Yoshito| Sato, Yasuharu|
Keywords intravascular large B-cell lymphoma diffuse large B-cell lymphoma soluble interleukin-2 receptor lactate dehy-drogenase B symptoms
Published Date 2023
Publication Title Journal of Clinical and Experimental Hematopathology
Volume volume63
Issue issue1
Publisher Japanese Society for Lymphoreticular Tissue Research
Start Page 25
End Page 31
ISSN 1346-4280
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Japanese Society for Lymphoreticular Tissue Research
File Version publisher
PubMed ID 36843068
DOI 10.3960/jslrt.22043
Web of Science KeyUT 000937326000001
Related Url isVersionOf https://doi.org/10.3960/jslrt.22043
Title Alternative Developing a scale to measure nurses' difficulty related to the treatment of gender dysphoric patients
FullText URL 134_22.pdf
Author Miyake, Maki| Oshima, Yoshitaka| Namba, Shihoko| Matsumoto, Yosuke| Horiuchi, Makiko| Yamada, Norihito|
Abstract  This study aimed to develop a scale to measure the perceived difficulty experienced by nurses in treating and caring for patients diagnosed with gender dysphoria and examine its reliability and validity. We developed a 26-item preliminary scale through discussions with experts in gender dysphoria treatment. We administered a questionnaire including this scale to 1,010 nurses working at Okayama University Hospital and analyzed the data of 346 nurses who had been involved in the treatment of gender dysphoria and had no missing responses.
 A total of 20 items consisting of two factors, “relationship building” and “negative emotion for gender dysphoria,” were extracted by exploratory factor analysis, and we used them in the final version of the scale. Cronbach's alpha coefficient for the entire scale was 0.879, indicating a high degree of internal consistency.
 However, the correlations with a communication skills scale (ENDCOREs) and the Scale of Gender Conception were limited, and the external validity could not be proven. This scale may be useful for evaluating nursing practice and educational support for nurses; however, there is room for further study on the scale validation.
Keywords 性別違和 (gender dysphoria) 関わりにくさ (difficulty in relating) コミュニケーション (communication) 性差観 (gender conception)
Publication Title Journal of Okayama Medical Association
Published Date 2022-04-01
Volume volume134
Issue issue1
Start Page 22
End Page 27
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.22
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.22
JaLCDOI 10.18926/AMO/64111
FullText URL 76_6_617.pdf
Author Kobayashi, Katsuhiro| Shibata, Takashi| Tsuchiya, Hiroki| Akiyama, Tomoyuki|
Abstract We developed an artificial intelligence (AI) technique to identify epileptic discharges (spikes) in pediatric scalp electroencephalograms (EEGs). We built a convolutional neural network (CNN) model to automatically classify steep potential images into spikes and background activity. For the CNN model’ training and validation, we examined 100 children with spikes in EEGs and another 100 without spikes. A different group of 20 children with spikes and 20 without spikes were the actual test subjects. All subjects were ≥ 3 to < 18 years old. The accuracy, sensitivity, and specificity of the analysis were >0.97 when referential and combination EEG montages were used, and < 0.97 with a bipolar montage. The correct classification of background activity in individual patients was significantly better with a referential montage than with a bipolar montage (p=0.0107). Receiver operating characteristic curves yielded an area under the curve > 0.99, indicating high performance of the classification method. EEG patterns that interfered with correct classification included vertex sharp transients, sleep spindles, alpha rhythm, and low-amplitude ill-formed spikes in a run. Our results demonstrate that AI is a promising tool for automatically interpreting pediatric EEGs. Some avenues for improving the technique were also indicated by our findings.
Keywords neural network deep learning electroencephalogram children spike
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-12
Volume volume76
Issue issue6
Publisher Okayama University Medical School
Start Page 617
End Page 624
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36549763
Web of Science KeyUT 000905195100001
FullText URL fulltext20221102-2.pdf
Author Hagiya, Hideharu| Onishi, Yuji| Shinohara, Natsumi| Tokuyasu, Mayumi| Imanishi, Aki| Fukushima, Shinnosuke| Nahar, Lutfun| Iio, Koji| Otsuka, Fumio|
Keywords Aging society Antimicrobial resistance Carbapenem-resistant Enterobacteriaceae Extended-spectrum beta-lactamase Infection prevention and control
Note © 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jiac.2022.07.014] . |
Published Date 2022-11
Publication Title Journal of Infection and Chemotherapy
Volume volume28
Issue issue11
Publisher Elsevier BV
Start Page 1578
End Page 1581
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases.
File Version author
PubMed ID 35921967
DOI 10.1016/j.jiac.2022.07.014
Web of Science KeyUT 000863109600009
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2022.07.014
FullText URL fulltext.pdf
Author Hagiya, Hideharu| Takase, Ryosuke| Honda, Hiroyuki| Nakano, Yasuhiro| Otsuka, Yuki| Kataoka, Hitomi| Uno, Mika| Ueda, Keigo| Takahashi, Misa| Ogawa, Hiroko| Hanayama, Yoshihisa| Otsuka, Fumio|
Keywords Traffic safety Older people Aging Motor vehicle accidents Frailty Dementia Polypharmacy Sarcopenia
Published Date 2022-10-11
Publication Title BMC Geriatrics
Volume volume22
Issue issue1
Publisher BMC
Start Page 792
ISSN 1471-2318
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 36221051
DOI 10.1186/s12877-022-03490-w
Web of Science KeyUT 000866114200002
Related Url isVersionOf https://doi.org/10.1186/s12877-022-03490-w
JaLCDOI 10.18926/AMO/63908
FullText URL 76_4_479.pdf
Author Ogawa, Chikako| Hirasawa, Akira| Sogawa, Reimi| Hasuoka, Kayoko| Tomida, Shuta| Futagawa, Mashu| Urakawa, Yusaku| Kochi, Mariko| Yamamoto, Hideki| Nakamura, Keiichiro| Masuyama, Hisashi|
Abstract A hereditary breast and ovarian cancer (HBOC) pedigree was detected via liquid biopsy, and cancer prevention was initiated for the patient’s daughter, after receiving a definitive result from BRCA genetic testing. A 48-yearold woman with ovarian cancer was administered precision medicine, which used cell-free DNA from plasma. The results revealed a pathogenic variant of BRCA1 as a presumed germline pathogenic mutation. We confirmed the germline pathological variant BRCA1 c.81-1G> A and suggested treatment with a PARP inhibitor. One of her three children had the variant, was diagnosed as an unaffected pathogenic variant carrier, and was advised to initiate surveillance.
Keywords hereditary breast and ovarian cancer (HBOC) BRCA 1 presumed germline pathogenic variants (PGPV) germline findings cancer precision medicine
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2022-08
Volume volume76
Issue issue4
Publisher Okayama University Medical School
Start Page 479
End Page 483
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36123164
Web of Science KeyUT 000882167300012
JaLCDOI 10.18926/AMO/63901
FullText URL 76_4_423.pdf
Author Takahashi, Satoshi| Kushibe, Takuya| Akezaki, Yoshiteru| Horiike, Norio|
Abstract We compared the effects of an exercise intervention with that of exercise combined with nutrition therapy in patients with possible malnutrition and sarcopenia admitted to a recovery rehabilitation ward, and we examined the differences in the patients’ physical function and activities of daily living (ADLs). There were 16 patients in the Exercise group with exercise therapy and ADL exercises, and 14 patients in the Combined intervention group with exercise therapy, ADL exercises, and nutrition therapy. The survey items were body weight, body mass index, grip strength, lower-leg circumference, gait speed, and ADLs, each of which was measured at the baseline and at 2 weeks, 4 weeks, and at discharge. Significant improvements in grip strength were observed in the Combined intervention group as follows: at 4 weeks>at 2 weeks (p<0.05), and at discharge>baseline and 2 weeks (p<0.05). There were no significant changes in the Exercise group, and an interaction was recognized in both groups. Comprehensive rehabilitation including nutrition therapy is necessary for patients with possible malnutrition and/or sarcopenia, as our results indicate that nutrition therapy in addition to exercise therapy has the effect of promoting improvements of physical function in such patients.
Keywords sarcopenia rehabilitation exercise therapy nutrition therapy grip strength
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-08
Volume volume76
Issue issue4
Publisher Okayama University Medical School
Start Page 423
End Page 428
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36123157
Web of Science KeyUT 000882167300008
FullText URL fulltext20220719-1.pdf
Author Matsuo, Toshihiko| Matsuo, Chie| Kayano, Masami| Mitsufuji, Aya| Satou, Chiyori| Matsuoka, Hiroaki|
Keywords strabismus amblyopia refractive error photorefraction preschool vision-screening program Spot vision screener visual acuity test 3.5-year-old children community health center nurse
Published Date 2022-7-16
Publication Title International Journal of Environmental Research and Public Health
Volume volume19
Issue issue14
Publisher MDPI
Start Page 8655
ISSN 1660-4601
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
DOI 10.3390/ijerph19148655
Related Url isVersionOf https://doi.org/10.3390/ijerph19148655
JaLCDOI 10.18926/AMO/63740
FullText URL 76_3_307.pdf
Author Sugiura, Satoshi| Kitamura, Yoshihisa| Izushi, Yasuhisa| Ushio, Soichiro| Sendo, Toshiaki|
Abstract In recent years, medical staff including physicians and nurses have been participating in home health care, reflecting the needs of an aging society in Japan. Pharmacists are also asked to work on home health care teams to ensure the medical safety of patients. It currently remains unclear whether direct communication, i.e. a meeting, between home-visiting physicians and pharmacists contributes to the proper use of medications and continuous medical care. We retrospectively analyzed the medication management guidance records of home-visited patients who received their first home visit between April 2014 and March 2017. We collected data on pharmacist inquiries, the duration of visits, and details from a meeting between home-visiting physicians and pharmacists. Thirty-five patients were included. At the first visit, the inquiry rate by pharmacists was 65.7%. The prescription question rate was significantly lower in patients with a meeting than in those without (p=0.033). The average duration of visits was significantly shorter for home-visited patients whose health care providers had a meeting (p=0.007). These results suggest that pharmacists who held a meeting with the home-visiting physician before the first patient visit were able to resolve drug-related issues earlier, which increased the work efficiency of home-visiting pharmacists.
Keywords home visit pharmacist meeting inquiry home health care
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-06
Volume volume76
Issue issue3
Publisher Okayama University Medical School
Start Page 307
End Page 315
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35790361
Web of Science KeyUT 000823568300001
FullText URL fulltext.pdf
Author Yamada, Yuto| Fujiwara, Masaki| Shimazu, Taichi| Etoh, Tsuyoshi| Kodama, Masafumi| So, Ryuhei| Matsushita, Takanori| Yoshimura, Yusaku| Horii, Shigeo| Fujimori, Maiko| Takahashi, Hirokazu| Nakaya, Naoki| Miyaji, Tempei| Hinotsu, Shiro| Harada, Keita| Okada, Hiroyuki| Uchitomi, Yosuke| Yamada, Norihito| Inagaki, Masatoshi|
Published Date 2022-06
Publication Title BMJ Open
Volume volume12
Issue issue6
Publisher BMJ Publishing Group
Start Page e060621
ISSN 2044-6055
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Author(s) (or their employer(s)) 2022.
File Version publisher
PubMed ID 35701062
DOI 10.1136/bmjopen-2021-060621
Web of Science KeyUT 000811702800009
Related Url isVersionOf https://doi.org/10.1136/bmjopen-2021-060621
JaLCDOI 10.18926/AMO/63414
FullText URL 76_2_195.pdf
Author Inoue, Shinichiro| Maeda, Isseki| Ogawa, Asao| Yoshiuchi, Kazuhiro| Terada, Seishi| Yamada, Norihito|
Abstract The clinical benefit of perospirone for treatment of delirium in patients with advanced cancer is not sufficiently clear. The objective of this study was to compare the safety and effectiveness of perospirone to those of risperidone for the treatment of delirium in patients with advanced cancer. This is a secondary analysis of a multicenter prospective observational study in nine psycho-oncology consultation services in Japan. The study used the Delirium Rating Scale (DRS) Revised-98 to measure effectiveness and the CTCAE (Common Terminology Criteria for Adverse Events) version 4 to assess safety. Data from 16 patients who received perospirone and 53 patients who received risperidone were analyzed. The mean age was 70 years in the perospirone group and 73 years in the risperidone group. Both groups showed a significant decrease in the total score of DRS-R-98 after three days of treatment (perospirone: 11.7 (7.9-15.4) to 7.0 (3.3-10.7), difference −4.7, effect size=0.72, p=0.003; risperidone: 15.5 (13.6-17.4) to 12.2 (10.1-14.2), difference −3.3, effect size=0.55, p=0.00). The risperidone group showed significant improvements in sleep-wake cycle disturbance, orientation, attention, and visuospatial ability. In the perospirone group, there was a significant improvement of sleep-wake cycle disturbance. The median daily dose of perospirone was 4 mg/day. There were fewer episodes of somnolence as an adverse event in the perospirone group. Low-dose perospirone was thus found to be effective for the treatment of delirium in patients with advanced cancer and may be associated with fewer episodes of over-sedation as an adverse event.
Keywords delirium cancer perospirone risperidone
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 195
End Page 202
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503448
Web of Science KeyUT 000792291900002
JaLCDOI 10.18926/AMO/63222
FullText URL 53_3_141.pdf
Author Nagata, Hiroshi| Ohta, Takeo| Aoyama, Hideyasu|
Abstract Medical students (fourth-year: n = 67; fifth-year: n = 63) estimated inpatients' feelings of anxiety, self-esteem, purpose-in-life, and multidimensional health locus of control. Their ratings were compared both with the ratings given by the 121 inpatients themselves and with those given by nursing practitioners (nurses and nursing students). Findings showed that the medical students overestimated inpatients' anxiety, while they underestimated the inpatients' purpose-in-life and internal health locus of control. Hence they underestimated, as did the nursing practitioners, the inpatients' positive emotional states and their positive attitude toward their own lives. Fifth-year medical students, with clinical experience, rated the inpatients' score of chance health locus of control higher than did the fourth-year medical students, who had no clinical experience. These findings indicate that medical students, like nursing practitioners, are inclined to pay more attention to inpatients' weaknesses than to their strengths.
Keywords inpatient's mental health anxiety self-esteem purpose-in-life health locus of control
Amo Type Brief Note
Publication Title Acta Medica Okayama
Published Date 1999-06
Volume volume53
Issue issue3
Publisher Okayama University Medical School
Start Page 141
End Page 145
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 1999 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 10410792
Web of Science KeyUT 000081201100007
FullText URL fulltext.pdf
Author Shinaoka, Akira| Kamiyama, Kazuyo| Yamada, Kiyoshi| Kimata, Yoshihiro|
Published Date 2022-01-10
Publication Title Scientific Reports
Volume volume12
Issue issue1
Publisher Nature Portfolio
Start Page 309
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
PubMed ID 35013357
DOI 10.1038/s41598-021-03637-6
Web of Science KeyUT 000741645800052
Related Url isVersionOf https://doi.org/10.1038/s41598-021-03637-6
JaLCDOI 10.18926/AMO/62769
FullText URL 75_5_567.pdf
Author Takase, Ryosuke| Hagiya, Hideharu| Honda, Hiroyuki| Nakano, Yasuhiro| Ogawa, Hiroko| Obika, Mikako| Ueda, Keigo| Kataoka, Hitomi| Hanayama, Yoshihisa| Otsuka, Fumio|
Abstract Influenza potentially has a high mortality rate when it affects the elderly. We aimed to examine the differences in clinical manifestations in patients with influenza according to their age. This multicenter prospective study was performed in six medical institutions in Okayama and Kagawa prefectures (Japan). Between December 1, 2019 and March 31, 2020, we collected data on adult patients diagnosed with influenza type A, who were strat-ified into younger (20-49 years), middle-aged (50-64 years), and older groups (≥ 65 years). We compared the presence or absence of fever, respiratory symptoms, and extrapulmonary symptoms according to age group. In total, 203 patients (113, younger; 51, middle-aged; and 39, older) were eligible for the analysis. The maxi-mum body temperature and temperature at first physician visit in the older group were significantly lower than those in the younger group. The incidence of respiratory symptoms was not different among the three groups. Chills, muscle pain, and arthralgia as systemic symptoms were noted significantly more frequently in the younger (80.9%) and middle-aged (75.5%) groups than in the older group (51.3%) (p = 0.002). Fever and sys-temic symptoms were less likely to appear in older patients, possibly resulting in the delaying of hospital visits among older adults.
Keywords influenza, elderly fever respiratory symptom
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-10
Volume volume75
Issue issue5
Publisher Okayama University Medical School
Start Page 567
End Page 574
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34703039
Web of Science KeyUT 000711561600003
NAID 120007166669
JaLCDOI 10.18926/AMO/62768
FullText URL 75_5_557.pdf
Author Takeshima Kohara, Hiroko| Ikeda, Mitsunori | Okawa, Masami|
Abstract This study examined the relationship between skin physiological indices and pressure ulcers in elderly people. The subjects were 55 bedridden elderly Japanese patients with a median age of 85 years. The following parame-ters were measured using non-invasive devices: skin surface temperature, moisture content in the stratum corneum, moisture content in the dermis, transepidermal water loss as an index of skin barrier function, skin erythema and skin elasticity. The sacral and 2 heel areas were observed as sites predisposed to pressure ulcers. Within one month after measuring the skin physiological indices, we confirmed pressure ulcers of National Pressure Ulcer Advisory Panel classification Stage II or worse based on medical records. Among the 55 patients, 4 (7.3%) prospectively developed a total of 5 pressure ulcers within 16 days. Only the skin erythema score was significantly higher with than without pressure ulcers (p < 0.001). We performed a binary logistic regression analysis and confirmed a significant relationship between pressure-ulcer development and the level of erythema (odds ratio = 1.026; 95% confidence interval: 1.011-1.042). Skin erythema increased before the development of pressure ulcers. Taken together, our results show that the high skin erythema score can be a predictive indicator of pressure ulcers.
Keywords elderly people erythema pressure ulcer skin
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-10
Volume volume75
Issue issue5
Publisher Okayama University Medical School
Start Page 557
End Page 565
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34703038
Web of Science KeyUT 000711561600002
NAID 120007166668
JaLCDOI 10.18926/AMO/62401
FullText URL 75_4_487.pdf
Author Kunna, Ezzan| Yamamoto, Taro| Nundu, Sabin| Akintije, Calliope | Elkhidir, Isam |
Abstract Ebola virus disease (EVD) is a highly contagious and fatal disease in humans. Healthcare providers (HCPs) are often at the frontline of epidemics and can thus be in jeopardy of contracting EVD. Sudan is at a great risk of an EVD outbreak, as it borders countries that experienced EVD outbreaks. It is therefore imperative in Sudan to assess the HCPs’ awareness and knowledge, attitude, and practice (KAP) about EVD for its control and man-agement and for preparedness. A KAP survey was conducted among 387 HCPs (physicians, nurses and labora-tory technicians) in the three main tertiary hospitals in Khartoum, Sudan. The majority of the survey respon-dents (54.5%) were females, < 30 years old (76.3%), and single (77.4%). Most (94%) had heard about EVD, 62% from classical media. Only 14% had received education or training regarding EVD. About 40% reported being adherent to universal precautions and 72% were willing to deal with EVD patients under safety precau-tions. Only 10% knew of any available standard national guidelines for EVD. Nearly half of the HCPs (47%) rated the potential risk of an EVD outbreak in Sudan as high, and 52% rated health authorities’ effort against it as weak. These findings revealed the HCPs’ insufficient knowledge of EVD and the necessary universal precau-tions. This lack of knowledge would negatively affect the HCPs’ preparedness toward any potential EVD out-break. There is a dire need to train HCPs in Sudan on the management of EVD, including preventive and con-trol measures.
Keywords Ebola virus Sudan healthcare provider knowledge attitude and practice
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 487
End Page 493
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511616
Web of Science KeyUT 000709282300002
NAID 120007146044
FullText URL fulltext20210818-1.pdf
Author Hagiya, Hideharu| Fujita, Koji| Kamiyama, Shinya| Ocho, Kazuki| Yamada, Haruto| Otsuka, Fumio|
Keywords antimicrobial resistance certified nurses in infection control infection prevention and control infectious disease doctors japan nosocomial infections surveillance
Published Date 2021-07-26
Publication Title Cureus
Volume volume13
Issue issue7
Publisher Cureus Inc.
Start Page e16643
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Copyright 2021 Hagiya et al.
File Version publisher
DOI 10.7759/cureus.16643
Web of Science KeyUT 000680008700016
Related Url isVersionOf https://doi.org/10.7759/cureus.16643
JaLCDOI 10.18926/AMO/62220
FullText URL 75_3_289.pdf
Author Miyamoto, Masakazu| Osawa, Kazuhiro| Miyoshi, Toru| Mori, Atsushi| Yoshikawa, Masaki| Oka, Takefumi| Ichikawa, Keishi| Nakamura, Kazufumi| Ito, Hiroshi|
Abstract Early treatment with an oral β-blocker is recommended in patients with a ST-segment–elevation myocardial infarction (STEMI). In this multicenter study, we evaluated the effects of a continuous administration of landiolol, an ultrashort-acting β-blocker, before primary percutaneous coronary intervention (PCI) on myocardial salvage and its safety in STEMI patients. A total of 47 Japanese patients with anterior or lateral STEMI undergoing a primary PCI within 12 h of symptom onset were randomized to receive intravenous landiolol (started at 3 μg/min/kg dose and continued to a total of 50 mg; n=23) or not (control; n=24). Patients with Killip class III or more were excluded. The primary outcome was the myocardial salvage index on cardiac magnetic resonance imaging (MRI) performed 5-7 days after the PCI. Cardiac MRI was performed in 35 patients (74%). The myocardial salvage index in the landiolol group was significantly greater than that in the control group (44.4±14.6% vs. 31.7±18.9%, respectively; p=0.04). There were no significant differences in adverse events at 24 h between the landiolol and control groups. A continuous administration of landiolol before a primary PCI may increase the degree of myocardial salvage without additional hemodynamic adverse effects within the first 24 h after STEMI.
Keywords myocardial infarction landiolol magnetic resonance imaging STEMI PCI
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-06
Volume volume75
Issue issue3
Publisher Okayama University Medical School
Start Page 289
End Page 297
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34176932
Web of Science KeyUT 000667147700004
NAID 120007089835
FullText URL fulltext20210601-1.pdf
Author Soga, Yoshihiko| Shirakawa, Yasuhiro| Fujiwara, Toshiyoshi| Ashiwa, Takako| Morimatsu, Hiroshi|
Keywords perioperative management nutrition dental oral management
Note This is a post-peer-review, pre-copyedit version of an article published in Current Oral Health Reports. The final authenticated version is available online at: http://dx.doi.org/10.1007/s40496-019-0217-3.|
Published Date 2019-04-15
Publication Title Current Oral Health Reports
Volume volume6
Issue issue2
Publisher Springer Science and Business Media LLC
Start Page 70
End Page 75
ISSN 2196-3002
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
NAID 120007042397
DOI 10.1007/s40496-019-0217-3
Related Url isVersionOf https://doi.org/10.1007/s40496-019-0217-3
JaLCDOI 10.18926/interdisciplinary/61888
Title Alternative Consideration about recognition of factors causing lack of confirmation in the nursing scene
FullText URL interdisciplinary_1_29_45.pdf
Author Zuo, Wanxin| Hyodo, Yoshimi| Tanaka, Tomoko| Gofuku, Akio|
Abstract In the work process of nurses with high risk, it is very urgent to take countermeasures against the “lack of confirmation” of the main factors. Therefore, the purpose of this study is to clarify the details of the factors leading to the lack of confirmation, grasp the number of near misses, and to explore what kind of factors the individual characteristics of the nurse who acts as a stopper. We recruited 500 nurses on the Web and asked about the frequency of near misses due to lack of confirmation, the awareness of the causes of lack of confirmation, self-evaluation of stoppers, and the reasons why near misses did not lead to accidents. As a result, three factors were extracted regarding the recognition of the factors of lack of confirmation: "lack of consciousness", "inability to concentrate", and "lack of knowledge / experience". Three factors were extracted for self-evaluation of stopper characteristics: "awareness," "verification," and "cautiousness". In order to reduce the lack of confirmation, it is necessary to secure and allocate appropriate personnel and create an environment where treatment can be concentrated. Nurses should also raise knowledge and the awareness of the importance of confirmation. In addition, it is necessary to improve the clinical judgment of new nurses in order to prevent near misses. And it is thought that new nurses will become more confident by accumulating experience and affirming their abilities from their superiors, seniors and colleagues.
Keywords lack of confirmation stoppers nurse
Publication Title Interdisciplinary Science
Published Date 2021-03-31
Volume volume1
Start Page 29
End Page 45
ISSN 2436-3227
language Japanese
File Version publisher
NAID 120007029897