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Author Ando, Eri| Nakasuka, Takamasa| Kubo, Toshio| Taniguchi, Akihiko| Ninomiya, Kiichiro| Kato, Yuka| Ichihara, Eiki| Ohashi, Kadoaki| Rai, Kammei| Hotta, Katsuyuki| Yamane, Masaomi| Miyahara, Nobuaki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords pulmonary aspergilloma allergic bronchopulmonary aspergillosis disaster
Published Date 2022-02-01
Publication Title Internal Medicine
Volume volume61
Issue issue3
Publisher JAPAN SOC INTERNAL MEDICINE
Start Page 379
End Page 383
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 34373373
DOI 10.2169/internalmedicine.7124-21
Web of Science KeyUT 000752787300015
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.7124-21
JaLCDOI 10.18926/AMO/63205
FullText URL 76_1_25.pdf
Author Sugimoto, Kohei| Kuroda, Masahiro| Yoshimura, Yuuki| Hamada, Kentaro| Khasawneh, Abdullah| Barham, Majd| Tekiki, Nouha| Konishi, Kohei| Ishizaka, Hinata| Shimizu, Yudai| Nakamitsu, Yuki| Al-Hammad, Wlla E. | Kamizaki, Ryo| Kanazawa, Susumu| Asaumi, Junichi|
Abstract The apparent diffusion coefficient subtraction method (ASM) was developed as a new restricted diffusionweighted imaging technique for magnetic resonance imaging (MRI). The usefulness of the ASM has been established by in vitro basic research using a bio-phantom, and clinical research on the application of the ASM for the human body is needed. Herein, we developed a short-time sequence for ASM imaging of the heads of healthy volunteers (n=2), and we investigated the similarity between the obtained ASM images and diffusion kurtosis (DK) images to determine the utility of the ASM for clinical uses. This study appears to be the first to report ASM images of the human head. We observed that the short-time sequence for the ASM imaging of the head can be scanned in approx. 3 min at 1.5T MRI. The noise reduction effect of median filter processing was confirmed on the ASM images scanned by this sequence. The obtained ASM images showed a weak correlation with the DK images, indicating that the ASM images are restricted diffusion-weighted images. The new shorttime imaging sequence could thus be used in clinical studies applying the ASM.
Keywords apparent diffusion coefficient apparent diffusion coefficient subtraction method diffusion kurtosis imaging restricted diffusion short-time imaging
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-02
Volume volume76
Issue issue1
Publisher Okayama University Medical School
Start Page 25
End Page 32
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35236995
Web of Science KeyUT 000762812700004
FullText URL fulltext.pdf
Author Higo, Hisao| Ohashi, Kadoaki| Tomida, Shuta| Okawa, Sachi| Yamamoto, Hiromasa| Sugimoto, Seiichiro| Senoo, Satoru| Makimoto, Go| Ninomiya, Kiichiro| Nakasuka, Takamasa| Nishii, Kazuya| Taniguchi, Akihiko| Kubo, Toshio| Ichihara, Eiki| Hotta, Katsuyuki| Miyahara, Nobuaki| Maeda, Yoshinobu| Toyooka, Shinichi| Kiura, Katsuyuki|
Keywords Idiopathic pulmonary fibrosis RNA sequencing Molecular therapeutic target Personalized therapy
Published Date 2022-02-07
Publication Title Respiratory Research
Volume volume23
Issue issue1
Publisher BMC
Start Page 20
ISSN 1465-993X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 35130915
DOI 10.1186/s12931-022-01940-y
Web of Science KeyUT 000752386100002
Related Url isVersionOf https://doi.org/10.1186/s12931-022-01940-y
FullText URL fulltext.pdf
Author Yamamoto, Hideki| Hirasawa, Akira|
Keywords homologous recombination deficiency (HRD) hereditary tumor germline cancer predisposition multi-gene panel testing (MGPT) BRCAness
Published Date 2021-12-29
Publication Title International Journal Of Molecular Sciences
Volume volume23
Issue issue1
Publisher MDPI
Start Page 348
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 35008774
DOI 10.3390/ijms23010348
Web of Science KeyUT 000741392000001
Related Url isVersionOf https://doi.org/10.3390/ijms23010348
FullText URL fulltext.pdf
Author Imamura, Mayu| Li, Tiantian| Li, Chunning| Fujisawa, Masayoshi| Mukaida, Naofumi| Matsukawa, Akihiro| Yoshimura, Teizo|
Keywords breast cancer chemokine lung metastasis fibroblasts macrophages tumor microenvironment
Published Date 2021-10-22
Publication Title Current Issues In Molecular Biology
Volume volume43
Issue issue3
Publisher MDPI
Start Page 1726
End Page 1740
ISSN 1467-3037
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 34698088
DOI 10.3390/cimb43030122
Web of Science KeyUT 000735852200001
Related Url isVersionOf https://doi.org/10.3390/cimb43030122
FullText URL fulltext.pdf
Author Fujihara, Miwa| Shien, Tadahiko| Shien, Kazuhiko| Suzawa, Ken| Takeda, Tatsuaki| Zhu, Yidan| Mamori, Tomoka| Otani, Yusuke| Yoshioka, Ryo| Uno, Maya| Suzuki, Yoko| Abe, Yuko| Hatono, Minami| Tsukioki, Takahiro| Takahashi, Yuko| Kochi, Mariko| Iwamoto, Takayuki| Taira, Naruto| Doihara, Hiroyoshi| Toyooka, Shinichi|
Keywords breast cancer YES1 T-DM1 dasatinib drug resistance
Published Date 2021-11-26
Publication Title International Journal Of Molecular Sciences
Volume volume22
Issue issue23
Publisher MDPI
Start Page 12809
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 34884609
DOI 10.3390/ijms222312809
Web of Science KeyUT 000735641400001
Related Url isVersionOf https://doi.org/10.3390/ijms222312809
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Author Okazaki, Mikio| Suzawa, Ken| Shien, Kazuhiko| Miyoshi, Kentaroh| Otani, Shinji| Yamamoto, Hiromasa| Sugimoto, Seiichiro| Yamane, Masaomi| Toyooka, Shinichi|
Published Date 2021-08-14
Publication Title Journal Of Surgical Case Reports
Volume volume2021
Issue issue8
Publisher Oxford Univ Press
Start Page rjab336
ISSN 2042-8812
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021.
File Version publisher
PubMed ID 34408837
DOI 10.1093/jscr/rjab336
Web of Science KeyUT 000732056400014
Related Url isVersionOf https://doi.org/10.1093/jscr/rjab336
FullText URL fulltext20211206-4.pdf
Author Yamamoto, Haruchika| Sugimoto, Seiichiro| Imanishi, Kentaro| Hashimoto, Kohei| Miyoshi, Kentaroh| Otani, Shinji| Yamane, Masaomi| Toyooka, Shinichi|
Keywords Lung transplantation (LT) pulmonary hypertension (PH) collateral vessel bleeding mortality
Published Date 2021-10
Publication Title Journal of Thoracic Disease
Volume volume13
Issue issue10
Publisher AME Publishing Company
Start Page 5658
End Page 5669
ISSN 2072-1439
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Journal of Thoracic Disease
File Version publisher
PubMed ID 34795916
DOI 10.21037/jtd-21-1119
Web of Science KeyUT 000717985900010
Related Url isVersionOf https://doi.org/10.21037/jtd-21-1119
FullText URL fulltext.pdf
Author Futagawa, Mashu| Yamamoto, Hideki| Kochi, Mariko| Urakawa, Yusaku| Sogawa, Reimi| Kato, Fumino| Okazawa-Sakai, Mika| Ennishi, Daisuke| Shinozaki, Katsunori| Inoue, Hirofumi| Yanai, Hiroyuki| Hirasawa, Akira|
Keywords RAD51D Splice variant Leiomyosarcoma Homologous recombination (HR) Cancer susceptibility Presumed germline pathogenic variant (PGPV)
Published Date 2021-11-27
Publication Title Hereditary Cancer In Clinical Practice
Volume volume19
Issue issue1
Publisher BMC
Start Page 48
ISSN 1731-2302
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s).
File Version publisher
PubMed ID 34838098
DOI 10.1186/s13053-021-00205-x
Web of Science KeyUT 000722986000001
Related Url isVersionOf https://doi.org/10.1186/s13053-021-00205-x
FullText URL K0006522_abstract_review.pdf K0006522_fulltext.pdf
Author HAGAR ALI ABDUL RAHEEM ABU QUORA |
Published Date 2021-09-24
Content Type Thesis or Dissertation
Grant Number 甲第6522号
Granted Date 2021-09-24
Thesis Type Doctor of Philosophy
Grantor 岡山大学
language English
FullText URL K0006473_abstract_review.pdf K0006473_fulltext.pdf
Author He, Fang|
Published Date 2021-09-24
Content Type Thesis or Dissertation
Grant Number 甲第6473号
Granted Date 2021-09-24
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2021 He, Matsumoto, Asano, Yamamura, Katsuyama, La Rose, Tomonobu, Komalasari, Sakaguchi, Rottapel and Wada.
FullText URL K0006437_abstract_review.pdf K0006437_fulltext.pdf
Author Hatono, Minami|
Published Date 2021-09-24
Content Type Thesis or Dissertation
Grant Number 甲第6437号
Granted Date 2021-09-24
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © Springer Science+Business Media, LLC, part of Springer Nature 2020
FullText URL fulltext20211026-1.pdf Supplementary Figures.docx Supplementary Table S1.docx Supplementary Table S2.xlsx Supplementary Table S3.docx Supplementary Table S4.docx Supplementary Table S5.xls Supplementary Table S6.docx
Author Sheta, Mona| Hassan, Ghmkin| Afify, Said M.| Monzur, Sadia| Kumon, Kazuki| Abu Quora, Hagar A.| Farahat, Mahmoud| Zahra, Maram H.| Fu, Xiaoying| Seno, Akimasa| Seno, Masaharu|
Keywords Cancer initiation Cancer stem cells iPSCs FGF2 Chronic inflammation
Note ©2021 Elsevier BV. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.canlet.2021.08.026] .|
Published Date 2021-11
Publication Title Cancer Letters
Volume volume521
Issue issue28
Publisher Elsevier BV
Start Page 142
End Page 154
ISSN 0304-3835
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Elsevier B.V.
File Version author
PubMed ID 34455015
DOI 10.1016/j.canlet.2021.08.026
Web of Science KeyUT 000704341600001
Related Url isVersionOf https://doi.org/10.1016/j.canlet.2021.08.026
JaLCDOI 10.18926/AMO/62781
FullText URL 75_5_659.pdf
Author Ino, Riku| Sada, Ken-ei | Miyauchi, Atsushi| Hashimoto, Daisuke| Nojima, Shigeru| Yamanaka, Shingo| Kawamura, Masafumi|
Abstract A 77-year-old woman with no history of malignancy presented with anorexia and bilateral lower extremity weakness. Her consciousness level worsened daily, so we performed a lumbar puncture. Cerebrospinal fluid (CSF) analysis indicated meningitis, but three rounds of CSF cytology showed no malignant cells. The patient’s carcinoembryonic antigen (CEA) level was highly elevated in CSF, but normal in serum. Through gadolinium-enhanced brain/spinal magnetic resonance imaging and gastrointestinal endoscopy, she was diagnosed with leptomeningeal carcinomatosis (LC) from gastric cancer. CEA level in CSF facilitated the diagnosis of LC from gastric cancer because there were no malignant cells on CSF cytology.
Keywords leptomeningeal carcinomatosis gastric cancer carcinoembryonic antigen cerebrospinal fluid cytology
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-10
Volume volume75
Issue issue5
Publisher Okayama University Medical School
Start Page 659
End Page 661
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34703051
Web of Science KeyUT 000711568400006
NAID 120007166666
FullText URL fulltext.pdf
Author Hotta, K.| Saeki, S.| Yamaguchi, M.| Harada, D.| Bessho, A.| Tanaka, K.| Inoue, K.| Gemba, K.| Shiojiri, M.| Kato, Y.| Ninomiya, T.| Kubo, T.| Kishimoto, J.| Shioyama, Y.| Katsui, K.| Sasaki, J.| Kiura, K.| Sugio, K.|
Keywords non-small-cell lung cancer locally advanced setting chemoradiation epidermal growth factor receptor
Published Date 2021-08
Publication Title ESMO Open
Volume volume6
Issue issue4
Publisher Elsevier
Start Page 100191
ISSN 2059-7029
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Author(s).
File Version publisher
PubMed ID 34153652
DOI 10.1016/j.esmoop.2021.100191
Web of Science KeyUT 000703610200037
Related Url isVersionOf https://doi.org/10.1016/j.esmoop.2021.100191
FullText URL fulltext20211014-1.pdf
Author Abe, Kodai| Kitago, Minoru| Kitagawa, Yuko| Hirasawa, Akira|
Keywords Cancer predisposition gene Familial pancreatic cancer Hereditary pancreatic cancer Multigene panel testing Surveillance
Published Date 2021-9-2
Publication Title International Journal of Clinical Oncology
Volume volume26
Issue issue10
Publisher Springer Science and Business Media LLC
Start Page 1784
End Page 1792
ISSN 1341-9625
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021
File Version publisher
PubMed ID 34476650
DOI 10.1007/s10147-021-02015-6
Web of Science KeyUT 000692076600001
Related Url isVersionOf https://doi.org/10.1007/s10147-021-02015-6
JaLCDOI 10.18926/AMO/62398
FullText URL 75_4_461.pdf
Author Murakami, Hiroyuki| Yoshioka, Takanori| Moriyama, Takashi| Ishikawa, Tatsunori| Makita, Masanori| Sunami, Kazutaka|
Abstract Bendamustine plus rituximab (B-R) is an effective therapy for relapsed or refractory (r/r) low-grade B-cell lymphoma (LGBCL) and mantle cell lymphoma (MCL); however, clinical data from Japanese patients treated with B-R therapy are limited. We retrospectively evaluated the efficacy and safety of B-R therapy in 42 patients who received B-R therapy at our hospital for r/r LGBCL and MCL. All patients received intravenous (IV) ritux-imab 375 mg/m2 on day 1 and IV bendamustine 90 mg/m2 on days 2 and 3 every 28 days for up to 6 cycles. The common histologic subtypes were follicular lymphoma (n = 29, 70%), marginal zone lymphoma (n = 6, 14%), and MCL (n = 5, 12%). The overall response rate was 93%, with 62% complete response and complete response unconfirmed. The median progression-free survival (PFS) was 38 months (95% confidence interval [CI], 24.6 to not reached [NR]), and the median overall survival (OS) was 80 months (95% CI, 60.7 to NR). Patients receiving a cumulative dose of bendamustine ≥ 720 mg/m2 showed a significantly longer PFS and OS. Grade 3/4 adverse events (≥ 10%) included neutropenia (55%), lymphopenia (69%), and nausea (24%). B-R therapy was effective and well tolerated, and the cumulative dose of bendamustine was associated with a favorable outcome.
Keywords bendamustine low grade B-cell lymphoma mantle cell lymphoma
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 461
End Page 469
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511613
Web of Science KeyUT 000697944600008
NAID 120007146041
JaLCDOI 10.18926/AMO/62394
FullText URL 75_4_431.pdf
Author Kunitomi, Toshiki| Nasu, Junichirou| Minami, Daisuke| Iwamoto, Takayuki| Nishie, Hiroyuki| Saito, Shinya| Fujiwara, Toshiyoshi| Matsuoka, Junji|
Abstract This study aimed to evaluate whether there are differences in the attitudes and practices of cancer pain manage-ment between medical oncologists and palliative care physicians. An online nationwide survey was used to collect responses from board-certified medical oncologists and palliative care physicians in Japan. The survey questionnaire comprised 30 questions. The differences in responses between medical oncologists and palliative care physicians were examined. Out of the 1,227 questionnaires sent, 522 (42.5%) were returned. After apply-ing the exclusion criteria, 445 questionnaires (medical oncologists: n = 283; palliative care physicians: n = 162) were retained for analysis. Among the questions about potential barriers to optimal cancer pain man-agement, both medical oncologists and palliative care physicians considered the reluctance of patients to take opioids due to fear of adverse effects as the greatest barrier. Significantly different ratings between medical oncologists and palliative care physicians were observed on 5 of the 8 questions in this area. Significantly differ-ent ratings were observed for all questions concerning pain specialists and their knowledge. For effective cancer pain management, it is important to account for differences in attitudes and practice between medical oncolo-gists and palliative care physicians.
Keywords cancer pain management opioid medical oncologist palliative care physician barriers
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 431
End Page 437
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511609
Web of Science KeyUT 000697944600004
NAID 120007146037
FullText URL fulltext.pdf
Author Akezaki, Yoshiteru| Nakata, Eiji| Kikuuchi, Masato| Tominaga, Ritsuko| Kurokawa, Hideaki| Okamoto, Masaki| Hamada, Makiko| Aogi, Kenjiro| Ohsumi, Shozo| Sugihara, Shinsuke|
Keywords breast cancer leisure surgery rehabilitation factor
Published Date 2021-08-22
Publication Title Healthcare
Volume volume9
Issue issue8
Publisher MDPI
Start Page 1078
ISSN 2227-9032
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 34442215
DOI 10.3390/healthcare9081078
Web of Science KeyUT 000690566600001
Related Url isVersionOf https://doi.org/10.3390/healthcare9081078
FullText URL fulltext20210824-1.pdf
Author Tekiki, Nouha| Kuroda, Masahiro| Ishizaka, Hinata| Khasawneh, Abdullah| Barham, Majd| Hamada, Kentaro| Konishi, Kohei| Sugimoto, Kohei| Katsui, Kuniaki| Sugiyama, Soichi| Watanabe, Kenta| Yoshio, Kotaro| Katayama, Norihisa| Ogata, Takeshi| Ihara, Hiroki| Kanazawa, Susumu| Asaumi, Junichi|
Keywords breast cancer field‑in‑field radiotherapy dose reference point acute skin toxicity dose distribution high‑dose area
Note This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License.|
Published Date 2021-7-21
Publication Title Molecular and Clinical Oncology
Volume volume15
Issue issue3
Publisher Spandidos Publications
ISSN 2049-9450
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Tekiki et al.
File Version publisher
PubMed ID 34349992
DOI 10.3892/mco.2021.2355
Web of Science KeyUT 000680476900001
Related Url isVersionOf https://doi.org/10.3892/mco.2021.2355