result 18181 件
| JaLCDOI | 10.18926/AMO/56868 |
|---|---|
| FullText URL | 73_3_247.pdf |
| Author | Yoshio, Kotaro| Wakita, Akihisa| Mitsuhashi, Toshiharu| Kitayama, Takahiro| Hisazumi, Kento| Inoue, Daisaku| Tajiri, Nobuhisa| Shiode, Tsuyoki| Akaki, Shiro| Kanazawa, Susumu| |
| Abstract | We investigated the feasibility of simultaneous integrated boost (SIB) volumetric modulated arc therapy (VMAT) using elective nodal irradiation (ENI) for middle or lower esophageal cancer and compared it with three-dimensional conformal radiotherapy (3D-CRT). The study included 15 patients. The prescribed doses included a standard dose (50.4 Gy) and a high dose (60 Gy) for the planning target volume (PTV) of the involved lesions. The objective of the whole lung volume receiving ≥ 20 Gy (V20Gy) was < 30%, and the mean lung dose (MLD) was < 20 Gy. The volumes of the lung receiving 5 Gy (V5Gy) and the heart receiving 30-50 Gy (V30-50Gy) were kept as low as reasonably achievable. As a result, SIB-VMAT showed superior dose conformity for the PTV (p<0.001). Although the lung V5Gy was significantly increased (p<0.001), the V20Gy and MLD showed no significant increase. The heart V30-50Gy showed a > 20% reduction in the mean against 3D-CRTs. Our results demonstrate the feasibility of SIB-VMAT for the treatment of middle or lower esophageal cancer with ENI. Although attention should be paid to the low-dose area of the lungs, SIB-VMAT would be a promising treatment option with improved outcomes for esophageal cancer. |
| Keywords | esophageal cancer middle and lower thoracic volumetric modulated arc therapy, 3D-CRT elective nodal irradiation |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 247 |
| End Page | 257 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235973 |
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Cancer (2012) 118:2632-2640.| Yu WW, Zhu ZF, Fu XL, Zhao KL, Mao JF, Wu KL, Yang HJ, Fan M, Zhao S and Welsh J: Simultaneous integrated boost intensity-modulated radiotherapy in esophageal carcinoma: early results of a phase II study. Strahlenther Onkol (2014) 190: 979-986.| Roeder F, Nicolay NH, Nguyen T, Saleh-Ebrahimi L, Askoxylakis V, Bostel T, Zwicker F, Debus J, Timke C and Huber PE: Intensity modulated radiotherapy (IMRT) with concurrent chemotherapy as definitive treatment of locally advanced esophageal cancer. Radiat Oncol (2014) 9: 191.| Chang CL, Tsai HC, Lin WC, Chang JH, Hsu HL, Chow JM, Yuan KS, Wu ATH and Wu SY: Dose escalation intensity-modulated radiotherapy-based concurrent chemoradiotherapy is effective for advanced-stage thoracic esophageal squamous cell carcinoma. Radiother Oncol (2017) 125: 73-79.| Alongi F, Fogliata A, Navarria P, Tozzi A, Mancosu P, Lobefalo F, Reggiori G, Clivio A, Cozzi L and Scorsetti M: Moderate hypofractionation and simultaneous integrated boost with volumetric modulated arc therapy (RapidArc) for prostate cancer. Report of feasibility and acute toxicity. Strahlenther Onkol (2012) 188: 990-996.| Peponi E, Glanzmann C, Kunz G, Renner C, Tomuschat K and Studer G: Simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) in nasopharyngeal cancer. Strahlenther Onkol (2010) 186: 135-142.| Vandecasteele K, De Neve W, De Gersem W, Delrue L, Paelinck L,Makar A, Fonteyne V, De Wagter C, Villeirs G and De Meerleer G: Intensity-modulated arc therapy with simultaneous integrated boost in the treatment of primary irresectable cervical cancer. Treatment planning, quality control, and clinical implementation. Strahlenther Onkol (2009) 185: 799-807.| Ogino I, Watanabe S, Sakamaki K, Ogino Y, Kunisaki C and Kimura K: Dosimetric predictors of radiation-induced pericardial effusion in esophageal cancer. Strahlenther Onkol (2017) 193: 552-560.| Wei X, Liu HH, Tucker SL, Wang S, Mohan R, Cox JD, Komaki R and Liao Z: Risk factors for pericardial effusion in inoperable esophageal cancer patients treated with definitive chemoradiation therapy. Int J Radiat Oncol Biol Phys (2008) 70: 707-714.| Grosshans D, Boehling NS, Palmer M, Spicer C, Erice R, Cox JD, Komaki R and Chang JY: Improving cardiac dosimetry: Alternative beam arrangements for intensity modulated radiation therapy planning in patients with carcinoma of the distal esophagus. Pract Radiat Oncol (2012) 2: 41-45.| Marks LB, Bentzen SM, Deasy JO, Kong FM, Bradley JD, Vogelius IS, El Naqa I, Hubbs JL, Lebesque JV, Timmerman RD, Martel MK and Jackson A: Radiation dose-volume effects in the lung. Int J Radiat Oncol Biol Phys (2010) 76(3 Suppl): S70-S76.| Paddick I: A simple scoring ratio to index the conformity of radiosurgical treatment plans. Technical note. J. Neurosurg (2000) 93 Suppl 3: 219-222. | Feuvret L, Noël G, Mazeron JJ and Bey P: Conformity index: a review. Int J Radiat Oncol Biol Phys (2006) 64: 333-342.| Fukada J, Shigematsu N, Takeuchi H, Ohashi T, Saikawa Y, Takaishi H, Hanada T, Shiraishi Y, Kitagawa Y and Fukuda K: Symptomatic pericardial effusion after chemoradiation therapy in esophageal cancer patients. Int J Radiat Oncol Biol Phys (2013) 87: 487-493.| Gayed IW, Liu HH, Yusuf SW, Komaki R, Wei X, Wang X, Chang JY, Swafford J, Broemeling L and Liao Z: The prevalence of myocardial ischemia after concurrent chemoradiation therapy as detected by gated myocardial perfusion imaging in patients with esophageal cancer. J Nucl Med (2006) 47: 1756-1762.| Speirs CK, DeWees TA, Rehman S, Molotievschi A, Velez MA, Mullen D, Fergus S, Trovo M, Bradley JD and Robinson CG: Heart Dose Is an Independent Dosimetric Predictor of Overall Survival in Locally Advanced Non-Small Cell Lung Cancer. J Thorac Oncol (2017) 12: 293-301.| Nutting CM, Bedford JL, Cosgrove VP, Tait DM, Dearnaley DP and Webb S: A comparison of conformal and intensity-modulated techniques for oesophageal radiotherapy. Radiother Oncol (2001) 61: 157-163.| Yom SS, Liao Z, Liu HH, Tucker SL, Hu CS, Wei X, Wang X, Wang S, Mohan R, Cox JD and Komaki R: Initial evaluation of treatment-related pneumonitis in advanced-stage non-small-cell lung cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys (2007) 68: 94-102.| Shaikh T, Churilla TM, Monpara P, Scott WJ, Cohen SJ and Meyer JE: Risk of radiation pneumonitis in patients receiving taxane-based trimodality therapy for locally advanced esophageal cancer. Pract Radiat Oncol (2016) 6: 388-394.| Shirakawa Y, Noma K, Maeda N, Tanabe S, Kuroda S, Kagawa S, Katsui K, Katayama N, Kanazawa S and Fujiwara T: Outcome of Radiation Monotherapy for High-risk Patients with Stage I Esophageal Cancer. Acta Med Okayama (2017) 71: 127-133.| |
| JaLCDOI | 10.18926/AMO/56867 |
|---|---|
| FullText URL | 73_3_241.pdf |
| Author | Utsumi, Masashi| Aoki, Hideki| Nishimura, Seitaro| Une, Yuta| Kashima, Hajime| Kimura, Yuji| Taniguchi, Fumitaka| Arata, Takashi| Katsuda, Koh| Tanakaya, Kohji| |
| Abstract | Gallbladder carcinoma (GBC) is a common malignancy with a poor prognosis. With the average life expectancy increasing globally, the incidence of GBC is predicted to increase as well. We investigated the safety and feasibility of surgical treatment for elderly patients with GBC. We retrospectively compared clinical pathological data and treatment outcomes in 45 consecutive GBC patients (23 patients ≥ 75 years [elderly group] and 22 patients < 75 years [younger group]) who underwent curative resection at the Iwakuni Center from January 2008 to December 2017. The proportion of preoperative comorbidities and anticoagulant use was significantly higher in the elderly group. The American Society of Anesthesiologists score was higher in the elderly versus the younger group, and the elderly group had significantly shorter operation times. Reduced activities of daily living was more common in the elderly versus younger group. The percentage of radical resection and overall 3-year survival (66.6% younger vs. 64.4% elderly) were similar between the groups. Controlling Nutritional Status (CONUT) score ≥ 3 and R0 resection were identified as prognostic factors for overall survival rate among all patients. After careful patient selection, |
| Keywords | elderly patient gallbladder carcinoma prognostic factor surgical treatment |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 241 |
| End Page | 246 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235972 |
| JaLCDOI | 10.18926/AMO/56866 |
|---|---|
| FullText URL | 73_3_235.pdf |
| Author | Horita, Masahiro| Nishida, Keiichiro| Hashizume, Kenzo| Sugimoto, Yoshihisa| Nasu, Yoshihisa| Nakahara, Ryuichi| Harada, Ryozo| Ozaki, Toshifumi| |
| Abstract | We investigated the prevalence of and risk factors for the progression of upper cervical lesions (UCLs) in patients with rheumatoid arthritis (RA). A retrospective analysis of 49 patients with RA (4 males, 45 females) was conducted. The UCLs included atlanto-axial subluxation and vertical subluxation. We investigated the clinical factors including the Disease Activity Score 28 based on C-reactive protein (DAS28-CRP) and the modified Health Assessment Questionnaire-Disability Index as well as radiographic changes between the baseline (at May 2010 to April 2013) and final follow-up. Forty patients (81.6%) were classified as the non-progressive group, and the other 9 patients (18.4%) comprised the progressive group. The progressive group’s final CRP values, baseline or final MMP-3 levels, DAS28-CRP, and rate of pre-existing lesions at baseline were all significantly higher than those of the non-progressive group (p=0.017, p=0.043, p=0.002, p=0.008, p<0.001, and p=0.008 respectively). A multivariate logistic regression analysis demonstrated that DAS28-CRP at baseline was a risk factor for radiographic progression (p=0.018, odds ratio: 2.54, 95% confidence interval: 1.17-5.51). Our findings indicate that higher disease activity might influence the progression of UCLs in patients with RA. |
| Keywords | rheumatoid arthritis upper cervical spine lesion risk factor radiological progression |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 235 |
| End Page | 240 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235971 |
| JaLCDOI | 10.18926/AMO/56865 |
|---|---|
| FullText URL | 73_3_229.pdf |
| Author | Hamasaki, Ichiro| Shibata, Kiyo| Shimizu, Takehiro| Kono, Reika| Morizane, Yuki| Shiraga, Fumio| |
| Abstract | During strabismus surgery using illumination from a light source, patients complain of photophobia. The NGENUITYⓇ (Alcon) system is equipped with a high-dynamic-range (HDR) camera. A 4K display viewed by wearing circularly polarized glasses provides clear three-dimensional images of the operative field. A light source is usually required for surgeries of the anterior segment (including strabismic surgery), but the digital processing function of the NGENUITYⓇ system allows image display in relatively dark regions even without a light source. We devised a novel ‘lights-out’ surgery that does not use a microscope’s light source, and we examined the usefulness of this technique in 2 cases of strabismic surgery. We performed strabismus surgery using the NGENUITYⓇ system in two patients between January and June 2018. The HDR function was used, and the aperture was opened to the maximum while the gain was adjusted. Surgery was conducted without using the microscope’s light source. We report the 2 cases’ results and evaluate the novel method. The surgeries were performed without problem even though the microscope’s light source was not used. The patients’ photophobia was alleviated. Lights-out surgery is a potentially useful modality for strabismus surgery. |
| Keywords | head-up surgery 3D vision system high dynamic range video enhancement strabismus surgery |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 229 |
| End Page | 233 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235970 |
| JaLCDOI | 10.18926/AMO/56864 |
|---|---|
| FullText URL | 73_3_223.pdf |
| Author | Sugiu, Kazuhisa| Furumatsu, Takayuki| Kodama, Yuya| Kamatsuki, Yusuke| Okazaki, Yoshiki| Okazaki, Yuki| Hiranaka, Takaaki| Ozaki, Toshifumi| |
| Abstract | Anterior cruciate ligament (ACL) reconstruction (ACLR) after ACL rupture improves the instability of the knee joint and decreases mechanical stress to the meniscus and articular cartilage. However, there are reports that post-traumatic osteoarthritis (PTOA) is observed over time following ACLR. In this study, we assessed changes in cartilage lesions by arthroscopic findings following anatomical double-bundle ACLR and at post-operative second-look arthroscopy about 14 months later. We retrospectively evaluated 37 knees in cases with patients <40 years of age who had undergone an anatomical double-bundle ACL reconstruction <1 year after ACL rupture injury from March 2012 to December 2016. Clinical results and arthroscopic cartilage/meniscal lesion were evaluated and compared between a cartilage lesion-detected group and intact-cartilage group. Surgery improved anteroposterior laxity and other clinical measures; however, cartilage lesions were detected at 11 sites during ACLR and at 54 sites at second-look arthroscopy. The periods from injury to second-look arthroscopy and from ACLR to second-look arthroscopy were significantly longer in the cartilage-lesion group (n=23) than in the intact-cartilage group (n=14). Conversely, 96% of meniscal damage observed during ACLR was cured at the time of second-look arthroscopy. Knee articular cartilage lesions after ACL rupture cannot be completely suppressed, even using the anatomical ACL reconstruction technique. This study suggested that articular cartilage lesions can progress to a level that can be confirmed arthroscopically at approximately 17 months after ACL injury. Therefore, in ACLR patients, the possibility of developing knee articular cartilage lesions and PTOA should be considered. |
| Keywords | anterior cruciate ligament reconstruction post-traumatic osteoarthritis meniscal lesion cartilage lesions second-look arthroscopy |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 223 |
| End Page | 228 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235969 |
| JaLCDOI | 10.18926/AMO/56863 |
|---|---|
| FullText URL | 73_3_213.pdf |
| Author | Nishina, Saori| Matsuura, Koji| Naruse, Keiji| |
| Abstract | We investigated the relationship between human sperm rheotaxis and motile sperm trajectories by using poly-(dimethylsiloxane) (PDMS)-based cylindrical microfluidic channels with inner diameters of 100 μm, 50 μm, and 70 μm, which corresponded to the inner diameter of the human isthmus, the length of a sperm and a diameter intermediate between the two, respectively. We counted the number of rheotaxic sperm and sperm with spiral motion. We also analyzed motile sperm trajectories. As the cylindrical channel diameter was decreased, the percentage of sperm cells exhibiting rheotaxis, the percentage of sperm cells exhibiting spiral motion, the frequency-to-diameter ratio of the sperm cells’ spiral trajectories, and the surface area of the microfluidic channel increased, while the flagellar motion at the channel wall decreased. The percentage of sperm exhibiting a spiral trajectory and the frequency-to-diameter ratio of the sperm cells’ spiral trajectories were thus affected by the channel diameter. Our findings suggest that the oviduct structure affects the swimming properties of sperm cells, guiding them from the uterus to the ampulla for egg fertilization. These results could contribute to the development of motile sperm-sorting microfluidic devices for assisted reproductive technologies. |
| Keywords | sperm motility trajectory microfluidic channel rheotaxis oviduct structure |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 213 |
| End Page | 221 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235968 |
| JaLCDOI | 10.18926/AMO/56862 |
|---|---|
| FullText URL | 73_3_205.pdf |
| Author | Mukai, Yuko| Sakurai, Toru| Watanabe, Toshiyuki| Sako, Tomoko| Sugimoto, Morito| Kimata, Yoshihiro| Mori, Yoshiko| Nagasaka, Takeshi| Namba, Yuzaburo| |
| Abstract | Intestinal vaginoplasty has several advantageous features, such as scarless surgery, low incidence of contraction of the reconstructed vagina, maintenance of vaginal depth, spontaneous mucus production, and a low rate of complications. Therefore, this technique is becoming popular in many countries. Following the global trend, the demand for intestinal vaginoplasty for transsexuals is also increasing in Japan. However, there are few reports on intestinal vaginoplasty in Japan. In this study, we examined the safety and effectiveness of rectosigmoid colon vaginoplasty in the Japanese population. We retrospectively surveyed 18 male-to-female transsexuals who underwent laparoscopic rectosigmoid colon vaginoplasty at the Okayama University Hospital Gender Center between October 2012 and December 2017. One patient had developed an anastomotic leak and 2 patients experienced vaginal prolapse, which needed revision surgery. Both adverse outcomes were comparable with those from previous studies. The anastomotic leak was managed adequately with conservative treatment. To avoid vaginal prolapse, it is important to decide the length of the rectosigmoid segment so that a pull on it does not cause it to become lax, while excessive stress on the feeder vessels is avoided. Based on our study, we concluded that rectosigmoid vaginoplasty was a reliable technique in the Japanese population. |
| Keywords | vaginoplasty male-to-female transsexuals rectosigmoid colon |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 205 |
| End Page | 211 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235967 |
| JaLCDOI | 10.18926/AMO/56861 |
|---|---|
| FullText URL | 73_3_197.pdf |
| Author | Nishimura, Takeshi| Naito, Hiromichi| Matsuyama, Shigenari| Ishihara, Satoshi| Nakao, Atsunori| Nakayama, Shinichi| |
| Abstract | Japan's population has been skewing toward the elderly, but the outcomes of advanced elderly trauma are not clear. Here we compared the outcomes of very elderly trauma patients (≧85 years old) with those of 65- to 84-year-old trauma patients. We retrospectively reviewed the medical records of patients treated at Hyogo Emergency Medical Center from August 2010 to August 2016; 631 patients were entered in the study. We divided them into the younger geriatrics (YG group, 65-84 years old: n=534) and older geriatrics (OG group, ≧85 years old: n=97). The group’s patient characteristics, mortality, 1-year survival rate, and Barthel index were tabulated and compared. The patients’ mean age was 75.6±7.5 years. There was no significant difference in mortality between the YG and OG groups (9.6% vs. 15.1%, odds ratio [OR] 1.73; 95% confidence interval [CI] 0.93-3.23, p=0.083). The 1-year survival rate (94.4% vs. 77.8%, OR 0.19, 95% CI 0.07-0.51; p<0.01) and Barthel index (Median score; 100 (IQR: 85-100) vs. 80 (IQR: 15-95), OR 0.98, 95% CI 0.97 to 0.99, p<0.01) differed significantly between the groups. Our study did not find a significant difference in-hospital mortality between patients in the YG group and those in the OG group. |
| Keywords | aged injury mortality morbidity trauma |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 197 |
| End Page | 203 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235966 |
| reference | Leskovan JJ, Justiniano CF, Bach JA, Cook CH, Lindsey DE, Eiferman DS, Papadimos TJ, Steinberg SM, Bergese SD, Stawicki SP and Evans DC: Anion gap as a predictor of trauma outcomes in the older trauma population: correlations with injury severity and mortality. Am Surg (2013) 79: 1203-1206.| Tornetta P, 3rd, Mostafavi H, Riina J, Turen C, Reimer B, Levine R, Behrens F, Geller J, Ritter C and Homel P: Morbidity and mortality in elderly trauma patients. J Trauma (1999) 46: 702-706.| Aitken LM, Burmeister E, Lang J, Chaboyer W and Richmond TS: Characteristics and outcomes of injured older adults after hospital admission. J Am Geriatr Soc (2010) 58: 442-449. | Mahoney FI and Barthel DW: Functional Evaluation: The Barthel Index. Md State Med J (1965) 14: 61-65.| Mondello S, Cantrell A, Italiano D, Fodale V, Mondello P and Ang D: Complications of trauma patients admitted to the ICU in level I academic trauma centers in the United States. Biomed Res Int (2014) 473419.| Hammer PM, Storey AC, Bell T, Bayt D, Hockaday MS, Zarzaur BL Jr., Feliciano DV and Rozycki GS: Improving geriatric trauma outcomes: A small step toward a big problem. J Trauma Acute Care Surg (2016) 81: 162-167.| Prin M and Li G: Complications and in-hospital mortality in trauma patients treated in intensive care units in the United States, 2013. Injury Epidemiology (2016) 3.| Zielinski MD, Kuntz MM, Polites SF, Boggust A, Nelson H, Khasawneh MA, Jenkins DH, Harmsen S, Ballman KV and Pieper R: A prospective analysis of urinary tract infections among elderly trauma patients. J Trauma Acute Care Surg (2015) 79: 638-642.| Polites SF, Habermann EB, Thomsen KM, Amr MA, Jenkins DH, Zietlow SP and Zielinski MD: Urinary tract infection in elderly trauma patients: review of the Trauma Quality Improvement Program identifies the population at risk. J Trauma Acute Care Surg (2014) 77: 952-959.| Magnotti LJ, Croce MA and Fabian TC: Is ventilator-associated pneumonia in trauma patients an epiphenomenon or a cause of death? Surg Infect (Larchmt) (2004) 5: 237-242.| Hyllienmark P, Brattstrom O, Larsson E, Martling CR, Petersson J and Oldner A: High incidence of post-injury pneumonia in intensive care-treated trauma patients. Acta Anaesthesiol Scand (2013) 57: 848-854.| Kisat M, Villegas CV, Onguti S, Zafar SN, Latif A, Efron DT, Haut ER, Schneider EB, Lipsett PA, Zafar H and Haider AH: Predictors of sepsis in moderately severely injured patients: an analysis of the National Trauma Data Bank. Surg Infect (Larchmt) (2013) 14: 62-68.| Wafaisade A, Lefering R, Bouillon B, Sakka SG, Thamm OC, Paffrath T, Neugebauer E and Maegele M: Epidemiology and risk factors of sepsis after multiple trauma: an analysis of 29,829 patients from the Trauma Registry of the German Society for Trauma Surgery. Crit Care Med (2011) 39: 621-628.| Bukur M, Habib F, Catino J, Parra M, Farrington R, Crawford M and Puente I: Does unit designation matter? A dedicated trauma intensive care unit is associated with lower postinjury complication rates and death after major complication. J Trauma Acute Care Surg (2015) 78: 920-927.| Reiff DA, Shoultz T, Griffin RL, Taylor B and Rue LW 3rd: Use of a Bundle Checklist Combined With Physician Confirmation Reduces Risk of Nosocomial Complications and Death in Trauma Patients Compared to Documented Checklist Use Alone. Ann Surg 2015 (262): 647-652.| Searle SD, Mitnitski A, Gahbauer EA, Gill TM and Rockwood K: A standard procedure for creating a frailty index. BMC Geriatr (2008) 8: 24.| Joseph B, Pandit V, Zangbar B, Kulvatunyou N, Hashmi A, Green DJ, OʼKeeffe T, Tang A, Vercruysse G, Fain MJ, Friese RS and Rhee P: Superiority of frailty over age in predicting outcomes among geriatric trauma patients: a prospective analysis. JAMA Surg (2014) 149: 766-772.| |
| JaLCDOI | 10.18926/AMO/56860 |
|---|---|
| FullText URL | 73_3_189.pdf |
| Author | Sakamoto, Shinji| Kawai, Hiroki| Okahisa, Yuko| Tsutsui, Ko| Kanbayashi, Takashi| Tanaka, Keiko| Mizuki, Yutaka| Takaki, Manabu| Yamada, Norihito| |
| Abstract | Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently-discovered autoimmune disorder in which antibodies target NMDAR in the brain. The number of reported cases of anti-NMDAR encephalitis has increased rapidly. Anti-NMDAR encephalitis can be mistakenly diagnosed as psychiatric disorders because many patients present with prominent psychiatric symptoms and visit psychiatric institutions first. Thus, psychiatrists should cultivate a better understanding of anti-NMDAR encephalitis. In this review, we present the mechanisms, epidemiology, symptoms and clinical course, diagnostic tests, treatment and outcomes of patients with anti-NMDAR encephalitis. Furthermore, we discuss the diversity of clinical spectra of anti-NMDAR encephalitis, and demonstrate a differential diagnosis of psychiatric disease from the perspective of psychiatry. |
| Keywords | NMDAR encephalitis psychiatric symptom schizophrenia mood disorder |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 189 |
| End Page | 195 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235965 |
| FullText URL | Tissue_Eng_A_2018_0348.pdf |
|---|---|
| Author | Sogawa, Chiharu| Eguchi, Takanori| Okusha, Yuka| Ono, Kisho| Ohyama, Kazumi| Iizuka, Motoharu| Kawasaki, Ryu| Hamada, Yusaku| Takigawa, Masaharu| Sogawa, Norio| Okamoto, Kuniaki| Kozaki , Ken-ichi| |
| Keywords | 3D tumoroid reporter assay Wnt/β-catenin signaling cancer metastasis metalloproteinase syngeneic transplantation tumoroid (tumor organoid) |
| Note | This is an Accepted Manuscript of an article published by Mary Ann Liebert| |
| Published Date | 2019-02-08 |
| Publication Title | Tissue Engineering Part A. |
| Volume | volume25 |
| Issue | issue19-20 |
| Publisher | Mary Ann Liebert |
| Start Page | 1413 |
| End Page | 1425 |
| ISSN | 19373341 |
| NCID | AA12306003 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 30734664 |
| NAID | 120006788780 |
| DOI | 10.1089/ten.TEA.2018.0348 |
| Web of Science KeyUT | 000489035900008 |
| Related Url | isVersionOf https://doi.org/10.1089/ten.TEA.2018.0348 |
| FullText URL | K0005995_abstract_review.pdf K0005995_summary.pdf K0005995_fulltext.pdf |
|---|---|
| Author | Su Su Maw| |
| Published Date | 2019-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5995号 |
| Granted Date | 2019-03-25 |
| Thesis Type | Doctor of Philosophy in Health Sciences |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005992_abstract_review.pdf K0005992_fulltext.pdf |
|---|---|
| Author | Muhomah Teresia Aluoch| |
| Published Date | 2019-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5992号 |
| Granted Date | 2019-03-25 |
| Thesis Type | Doctor of Philosophy in Agriculture |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005979_abstract_review.pdf K0005979_fulltext.pdf |
|---|---|
| Author | Xu, Zhihan| |
| Published Date | 2019-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5979号 |
| Granted Date | 2019-03-25 |
| Thesis Type | Doctor of Philosophy in Engineering |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005971_abstract_review.pdf K0005971_fulltext.pdf |
|---|---|
| Author | Yano, Yusuke| |
| Published Date | 2019-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5971号 |
| Granted Date | 2019-03-25 |
| Thesis Type | Doctor of Philosophy in Engineering |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005970_abstract_review.pdf K0005970_fulltext.pdf |
|---|---|
| Author | Md. Al-Amin, Khandakaer| |
| Published Date | 2019-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5970号 |
| Granted Date | 2019-03-25 |
| Thesis Type | Doctor of Philosophy in Engineering |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005965_abstract_review.pdf K0005965_summary.pdf |
|---|---|
| Author | Meissner Andreas| |
| Published Date | 2019-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5965号 |
| Granted Date | 2019-03-25 |
| Thesis Type | Doctor of Philosophy in Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005955_abstract_review.pdf K0005955_fulltext.pdf |
|---|---|
| Author | New Haymar Lynn| |
| Published Date | 2019-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5955号 |
| Granted Date | 2019-03-25 |
| Thesis Type | Doctor of Philosophy in Pharmaceutical Sciences |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005919_abstract_review.pdf.pdf K0005919_summary.pdf.pdf K0005919_fulltext.pdf |
|---|---|
| Author | Matsuada, Hiroyuki| |
| Published Date | 2019-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5919号 |
| Granted Date | 2019-03-25 |
| Thesis Type | Doctor of Philosophy in Dental Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005918_abstract_review.pdf K0005918_summary.pdf K0005918_fulltext.pdf |
|---|---|
| Author | Hosogi, Mika| |
| Published Date | 2019-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5918号 |
| Granted Date | 2019-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005917_abstract_review.pdf K0005917_summary.pdf K0005917_fulltext.pdf |
|---|---|
| Author | Miki, Kentaro| |
| Published Date | 2019-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5917号 |
| Granted Date | 2019-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
