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Author Inoue, Taeko| Morinaga, Hiroshi|
Published Date 1972-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume41
Content Type Data or Dataset
JaLCDOI 10.18926/40149
Title Alternative A subsequent report on the new McKinney type mass spectrometer in the Institute for Thermal Spring Research, Okayama University
FullText URL pitsr_041_003_007.pdf
Author Matsubaya, Osamu|
Abstract Since the installation in April 1970, the McKinney type mass spectrometer has maintained a good condition and about 5000 isotopic analyses of oxygen, carbon and sulfer has been cerried out so far. The ion source filament was changed to spiral one from single wire. Consequently three times sensitivity and the longer life of filament were obtained. Gradual changes in the ratio of potential divider (β) and the sensitivity (|△ E(0)(2)|/E(0)(1)) for the difference of β have been observed (Table 1). Because these changes are opposite in trend but similar in degree, it is supposed that these changes are caused by decrease of feed-back resister value in the balancing system. Although there remain some problems in the corrections for the difference in observed isotopic tatio between two cases that a same CO(2) is fed to ion source from the ST side of inlet system on the one hand and from the X side on the another, the reproducibility of the measurement of isotopic ratio for long period is about ±O.1‰ (Table 2, Fig. 1). δ(18)O values of standard waters, MSA-1 and MSA-2, measured during a period from May to Dec. 1970 and in Sep. 1971 yielded good agreements implying the reproducibility of the measurement to be constant (Table 3). Both calculated δ(18)O values relative to a given sample based on each observed δ(18)O value relative to two different samples agreed each other. It is concluded that the linearity of observed a-value holds over a range of 30‰ (Table 4).
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 3
End Page 7
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398147
JaLCDOI 10.18926/40148
Title Alternative The effect of pH of water on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique
FullText URL pitsr_041_001_002.pdf
Author Matsubaya, Osamu|
Abstract The effect of pH of water on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique was studied. In this study, a new type of reaction vessel was used (Fig. 1). The reaction time for equilibration using this new reaction vessel was nearly equal to that in the previous study (Fig. 2). The oxygen isotopic ratios of each two samples of pH 2, 4, 7, 8, 9, and 10 were measured. There is no significant difference between the observed δ(18)O values of these samples (Table 1). Therefore it is concluded that the effect of pH of water needs not to be taken into account on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique.
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 1
End Page 2
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398148
Author 岡山大学温泉研究所|
Published Date 1972-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume41
Content Type Others
JaLCDOI 10.18926/40143
Title Alternative Rheumatoid arthritis and Sjögren's syndrome
FullText URL 042_031_045.pdf
Author Ichikawa, Yukinobu|
Abstract 1. Parotid Sialography Parotid sialograms were investigated in 29 patients with classical or definite RA according to the criteria of the American Rheumatism Association (one of whom had scleroderma), 5 patients with SLE (according to the Dubois's criteria, three were definite, one probable and another possible SLE), 3 patients with other autoimmune diseases (Hashimoto's thyroiditis, colitis ulcerosa and undiagnosed collagen disease), 3 patients with polyarthralgia and 10 patients with nonautoimmune diseases. Sialographic technique was performed by modified Rubin's Method using contrast medium Conray-400. Sialectasis which is pathognomonic of Sjögren's syndrome (SS) alone was observed in 6 patients with RA (20.7%) (3 punctate and 3 globular patterns) and 2 patients with SLE (one punctate and another globular pattern). Retention of the contrast medium in the duct for at least 5 minutes after the injection was observed in patients with RA, one patient with SLE and one patient with colitis ulcerosa. Sial ectasis and retention almost always existed together, and were observed in patients from young to older one. Although dilatation of the Stensen's duct and subalveolar dissection also existed together, they were observed in only older patients. It appeared that the former is the specific findings of SS and the latter is the non-specific findings according to the aging. Dry mouth was complained in 7 sialectasis (87.5%), 3 subalveolar dissection (60.0%), 10 retention (62.5%) and 9 normal sialogram (37.5%). Salivary hyposecretion (less than 10 ml/10min) was observed in 4 sialectasis (50%), one subalveolar dissection (20%), 6 dilatation of the Stensen's duct (37.5%), 5 retention (45.5%) and one normal sialogram (4.2%). These results show that sialectasis and retention are well correlated with salivary hyposecretion, but dry mouth is not so diagnostic in SS. Two patients with SLE had sialectasis were young women and showed normal salivary and lacrimal secretion. These cases may be supported by Heaton's hypothesis that SS is a benign and chronic form of SLE, or thay may be a subclinical state of SS. 2. Schirmer test Sixty seven patients (36RA, 6SLE, 3 other autoimmune diseases, 3 polyarthralgia and 19 non-autoimmune diseases) were examined by Schirmer test. Besides lacrimal hyposecretion was observed in RA and other autoimmune diseases, it began in younger age. These results show that autoimmune diseases have a sicca element in themselves. Compared with the results of sialography, Schirmer test was not correlated with sialectasis and retention. Dry eye was complained in only 4 patients (13.3%) with lacrimal hyposecretion (less than 10mm/5min) and all patients with dry eye had keratoconjunctivitis sicca (KCS). Dry eye is more diagnostic than Schirmer test. 3. Corneal staining by 1% rose bengal solution Twenty five patients with RA or SLE were examned corneal staining (Holm's type A) was observed in 5 patients with RA (20%). Staining of the medial and lateral bulbar conjunctiva (Holm's type B and C) were observed in 6 patients with RA (24%) and one patient with SLE. Nine patients with positive staining (type A, B and C) (75%) showed lacrimal hyposecretion. Dry eye was complained in 4 patients with type A staining (80%), but no patient with type B and C complained dry eye. Dry eye appears to be specific for the diagnosis of SS as sialectasis on the sialogram. 4. Salivary secretion All amount of saliva was collected during ten minutes chewing two pieces of gum. All of 21 patients with non-autoimmune diseases showed more than 10 ml/10min, and slight degree of salivary hyposecretion was observed with aging. Nine patients with RA (25.7%) showed salivary hyposecretion (less than 10ml/10min), besides it began in younger age. It was also observed in patients with other autoimmune diseases. Only 36.4% patients with salivary hyposecretion showed sialectasis on the sialogram. It can be supposed that patients with sialectasis and good salivary secretion are subclinical states of SS, and that this state is depends on the compensative function of the glands. Therefore, it is impossible to suppose the salivary dysfunction from the complaints of patients alone. It is required that saliva must be analysed not only quantitativly but also qualitativly (such as RA factor, complement and lysozome). Dry mouth was not only complained in 9 patients who showed salivary hyposecretion (81.8%). but in 10 patients showed normal secretion (50%). Dry mouth appears to be less specific for the diagnosis of SS than dry eye. 5. Diagnosis of SS Vanslow's criteria of SS was modified as follows. (1) Major : ① Sialectasis or salivary gland enlargement ② Positive corneal staining (type A) ③ Classical or definite RA (according to the criteria of the ARA) (2) Minor : ① Arthritis ② History ot salivary gland swelling ③ Dry mouth or salivary hyposecretion (less than 10ml/10min) ④ Dry eye or positive Schirmer test (less than 10mm/5min). Three major was diagnosed as definite, 2 major as probable and one major with one or more minor as possible SS. Of 35 patients with RA, definite (8.6%), probable (17.1%) and possible SS (54.3%) were obserevd. Two of SLE (33.3%) were possible SS. One patients with undiagnosed collagen disease was possible SS. Clinically, definite and probable SS may be diagnosed as Sjögren's syndrome. Two possible SS with SLE may be supporsed as subclinical states of SS who do not yet exhibite full criteria. Compared with the clinical and laboratory findings of these definite, probable and possible SS with RA, it was supporsed that positive antinuclear factor or positive LE cells in RA patients almost always represents SS, drug allergy, especially to gold therapy may be a manifestation of SS. Hypergammaglobulinemia, extreme elevation of erythrocyte sedimentation rate, struma, lymphnode enlargement in RA patients must be suspected of SS. Although one possible SS with SLE and one probable SS with RA showed positive ANF (peripheral pattern), it is impossible to differentiate SS from SLE by ANF alone. Because Suzuki et al. reported that 15.4% of SS had showed positive ANF (peripheral pattern). Examinations of salivary glands including sialography must be performed in patients with SLE in the future. To detect a subclinical SS, sialography and corneal staining must be performed even in patients with no sicca symptom, because of the compensatory functions of salivary and lacrimal glands.
Publication Title 岡山大学温泉研究所報告
Published Date 1973-03-25
Volume volume42
Start Page 31
End Page 45
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532309
JaLCDOI 10.18926/40140
Title Alternative Zoned alternation of gibbsite and clay mInerals in the vermicular gibbsite
FullText URL pitsr_042_001_007.pdf
Author Tazaki, Kazue|
Abstract Vermicular gibbsite aggregates found in the weathered pumice layer (the Kurayoshi pumice) at Yotsuzuka, western part of Tottori Prefecture, range in size from 5 to lOmm (Fig.1). They are more or less twisted and show some cleavages perpendicular to the long axis. Vermicular gibbsite are milky white colored and usually coated with dark brown color. X-ray diffraction patterns show strong renections for gibbsite, kaoline minerals, hydrobiotite and a relatively small amount of hydrated halloysite (Fig.3), Kaoline minerls are rather abundant at the white part. On the other hand, the dark brown part is rich in hydrobiotite. Differential thermal analysis shows the endothermic reaction for the dehydration of gibbsite at 310℃ and of kaoline minerals, hydrated halloysite and hydrobiotite at 550℃ (Fig.4). Electron microscopy shows that the gibbsite consist of peculiarly warped rods (Plate 1). The clay minerals which are looked like "cracked rice grain" are seemingly kaoline minerals or hydrated halloyslte. By the electron microprobe scanning across the vermicular gibbsite, the triform structure is revealed, such as the gibbsite rich part, the hydrobiotite rich part and kaoline minerals rich part (Fig.5 and 6). Gibbsite and clay minerals (hydrobiotite or kaoline minerals) grow alternately zone by zone (Fig.7). The width of each zone ranges in size from 20 to 40 micron.
Publication Title 岡山大学温泉研究所報告
Published Date 1973-03-25
Volume volume42
Start Page 1
End Page 7
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398144
Author 岡山大学温泉研究所|
Published Date 1973-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume42
Content Type Others
JaLCDOI 10.18926/40136
Title Alternative Oxygen Isotopic Composition of Water in the Living Things : Preliminary Analyses and Discussions
FullText URL pitsr_044_061_075.pdf
Author Kishima, Noriaki|
Abstract Oxygen isotope analysis was carried out, by use of a new method (oxalate equilibration method) of preparing CO(2) for mass spectrometry, on water samples extracted from a number of biological samples collected in Misasa Town and Hashizu Coast, Tottori Prefecture. The δ values (the per mil enrichment of (18)O in sample waters relative to the Standard Mean Ocean Water) were suggested to be distributed in the living things as follows. The water absorbed by plant roots was supposed to have the same δ value with the water outside it (δs. about -8‰), and in a rapidly transpiring plant, this water reached the leaves, partly infiltrating into the phloem. When transpiration was slow, on the other hand, the isotopic composition of ascending xylem sap was modified by the exchange of water with phloem. where leaf water with a higher δ value was migrating. As Gonfiantini et aI. (1965) and Dongmann et al. (1972) have odserved, leaf waters were enriched markedly in (18)O in the daytime. A criterion of the δ of leaf water may be the sum of δs and △δ that corresponds to the (18)O fractionation factor in the H(2)O(I)-H(2)O(v) system. The sum comes to about 0‰ at ordinary leaf temperatures. and really δ values near 0‰ were observed in leaves of some herbaceous plants, in exudate from a tip of vine of Kudzu, in body fluid of herbivorous insects, etc., but higher δs (up to +19‰) were also observed in some other leaves such as pine needles, Especially leaves showed an increase in δ by about 10 ‰ toward the pnd of November when the average temperature fell below 10℃, probably because of accumulation of the daily enrichment as a resul t of slow water absorption and circulation. A few plant species grown on a dune were analyzed and it seemed that, among them, herbaceous plants were dependent on spraied sea water and pine trees on ground water. δ's of petal water were dispersed (-9~-3‰), probably according to the volume-to-transpirational flux ratio of water in the petals. Succurent fruits in enlarging stage seemed to have lower δ's near δs, but in maturing stagp δ's increaspd to about -4‰, i.e., to the avpraged δ of Ieaf water in the day and night. Herbivorous insects (imagines and la rvae) in general had distinctly higher δ values than carnivorous insects, the border being at -1‰. However, lower δ's at about -5‰ were obserbed on aphides which might have been sucking somewhat dilutpd leaf water from seave tube cells. Sometimes the δ of a herbivorous insect was a few per mil higher than that of the leaf it was nibbling, probably as a result of evaporation of water from the insect and of respiration. The level at about -3‰ common for carnivorous insects could not be explained, although tipula and chironomus making a swarm also showed a δ value on the level. Blood of a heron did not show such a low δ as supposed from its food habit. As compared with the drinking water of -8‰, blood and urine were found to have an identical δ in the range of -4 to -5‰ in either mouse or man, The δ value of the oxidation water produced in man's body was estimated to be about -6‰ from an approximate water balance.
Publication Title 岡山大学温泉研究所報告
Published Date 1975-03-25
Volume volume44
Start Page 61
End Page 75
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002383784
JaLCDOI 10.18926/AMO/40130
FullText URL 64_4_225.pdf
Author Ohtsu, Tadahiro| Kokaze, Akatsuki| Shimada, Naoki| Kaneita, Yoshitaka| Shirasawa, Takako| Ochiai, Hirotaka| Hoshino, Hiromi| Takaishi, Masahiro|
Abstract Over the past two decades, the liquor industry in Japan has strived to address alcohol-related problems through initiatives such as warnings in the various media. In this study, we conducted an Internet-based questionnaire survey to examine general consumer awareness of such warnings, and the media by which they are conveyed, on the consumption of alcoholic beverages. A total of 985 subjects (males:487, females:498) in age groups ranging from 20s to 70s responded (response rate:22.4%). The awareness rates for warnings regarding underage drinking, drunk driving, and drinking during pregnancy, and those for messages encouraging moderation in drinking, were 96.4%, 83.7%, 59.6%, and 45.5%, respectively. Logistic regression analysis adjusted for habitual alcohol consumption demonstrated significant gender- and/or age-based differences in the rates of awareness of warnings and the media publicizing them. For example, the odds ratio of awareness among women of warnings against underage drinking was significantly higher than that of awareness among men. Issues that must be addressed in the future include:(1) increasing public awareness about messages regarding drinking during pregnancy and drinking in moderation;(2) reviewing the wording of warnings to make them more effective;and (3) devising and employing, on a regular basis, more effective means of transmitting messages in consideration of gender and age.
Keywords alcoholic beverages warnings consumer awareness Internet-based survey
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2010-08
Volume volume64
Issue issue4
Publisher Okayama University Medical School
Start Page 225
End Page 232
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 20802539
Web of Science KeyUT 000281384400003
JaLCDOI 10.18926/AMO/40128
FullText URL 64_4_213.pdf
Author Otani, Hiroyuki| Otsuka, Fumio| Inagaki, Kenichi| Suzuki, Jiro| Makino, Hirofumi|
Abstract Aldosterone production occurs in the adrenal cortex, and is regulated primarily by angiotensin II (Ang II), potassium and adrenocorticotropin (ACTH). In the presence of the aldosterone stimulators, steroidogenesis is further governed by local autocrine and/or paracrine factors in the adrenal cortex. We reported the presence of functional bone morphogenetic protein (BMP) system in the adrenal cortex and also demonstrated that BMP-6 increases Ang II-induced aldosterone production, which could be involved in the "aldosterone breakthrough" phenomenon. Aldosterone breakthrough is the phenomenon by which circulating aldosterone concentrations increase above pre-treatment levels after long-term therapy with ACE inhibitors or Ang II type 1 receptor antagonists (ARB). This phenomenon may lead to important clinical consequences since increased aldosterone in a high-salt state facilitates cardiovascular and renal damage in hypertensive patients. We found that long-term ARB treatment reverses the reduction of aldosterone synthesis by adrenocortical cells, thereby causing "cellular aldosterone breakthrough". The availability of BMP-6 in the adrenal cortex may be at least partly involved in the occurrence of cellular escape from aldosterone suppression under chronic treatment with ARB.
Keywords adrenal cortex angiotensin II aldosterone bone morphogenetic protein
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2010-08
Volume volume64
Issue issue4
Publisher Okayama University Medical School
Start Page 213
End Page 218
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 20802537
Web of Science KeyUT 000281384400001
Author Isobe, Midori|
Published Date 2010-06-30
Publication Title
Content Type Thesis or Dissertation
Author 野崎 貴博| 中村 大介| 光本 順| 能城 修一| 佐々木 由香|
Published Date 2006-03-15
Publication Title 岡山大学構内遺跡発掘調査報告
Volume volume22
Content Type Research Paper
Author 岩﨑 志保| 野崎 貴博| 高田 貫太| 高田 浩司| 山本 悦世| 能城 修一|
Published Date 2005-03-20
Publication Title 岡山大学構内遺跡発掘調査報告
Volume volume21
Content Type Research Paper
Author 光本 順| 能城 修一|
Published Date 2005-03-15
Publication Title 岡山大学構内遺跡発掘調査報告
Volume volume20
Content Type Research Paper
Author 山本 悦世| 忽那 敬三| 光本 順| 岩﨑 志保| 能城 修一|
Published Date 2004-02-27
Publication Title 岡山大学構内遺跡発掘調査報告
Volume volume19
Content Type Research Paper
Author 岩﨑 志保| 野崎 貴博| 横田 美香|
Published Date 2003-03-26
Publication Title 岡山大学構内遺跡発掘調査報告
Volume volume17
Content Type Research Paper
Author 山本 悦世| 岩﨑 志保| 髙田 浩司| 宇田川 武久| 能城 修一| 柴田 次夫|
Published Date 2003-03-31
Publication Title 岡山大学構内遺跡発掘調査報告
Volume volume16
Content Type Research Paper
Author 小林 青樹| 野崎 貴博|
Published Date 2000-02-29
Publication Title 岡山大学構内遺跡発掘調査報告
Volume volume15
Content Type Research Paper
Author 松木 武彦| 山本 悦世|
Published Date 1997-03-31
Publication Title 岡山大学構内遺跡発掘調査報告
Volume volume11
Content Type Research Paper
Author 土井 基司| 山本 悦世|
Published Date 1995-12-30
Publication Title 岡山大学構内遺跡発掘調査報告
Volume volume9
Content Type Research Paper