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FullText URL K0004811_abstract_review.pdf K0004811_fulltext.pdf
Author Koga, Hikari|
Published Date 2013-06-30
Content Type Thesis or Dissertation
Grant Number 甲第4811号
Granted Date 2013-06-30
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language Japanese English
FullText URL K0004810_abstract_review.pdf K0004810_fulltext.pdf
Author Nishikawa, Toshio|
Published Date 2013-06-30
Content Type Thesis or Dissertation
Grant Number 甲第4810号
Granted Date 2013-06-30
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language Japanese English
Author Hasei, Joe| Sasaki, Tsuyoshi| Tazawa, Hiroshi| Osaki, Shuhei| Yamakawa, Yasuaki| Kunisada, Toshiyuki| Yoshida, Aki| Hashimoto, Yuuri| Onishi, Teppei| Uno, Futoshi| Kagawa, Shunsuke| Urata, Yasuo| Ozaki, Toshifumi| Fujiwara, Toshiyoshi|
Published Date 2013-03
Publication Title Molecular Cancer Therapeutics
Volume volume12
Issue issue3
Content Type Journal Article
FullText URL K0004809_abstract_review.pdf K0004809_fulltext.pdf
Author Obika, Masanari|
Published Date 2013-06-30
Content Type Thesis or Dissertation
Grant Number 甲第4809号
Granted Date 2013-06-30
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language Japanese English
Author Tayra, Judith Thomas| Kameda, Masahiro| Yasuhara, Takao| Agari, Takashi| Kadota, Tomohito| Wang, Feifei| Kikuchi, Yoichiro| Liang, Hanbai| Shinko, Aiko| Wakamori, Takaaki| Vcelar, Brigitta| Weik, Robert| Date, Isao|
Published Date 2013-03-28
Publication Title Brain Research
Volume volume1502
Content Type Journal Article
Author Naito, H.| Takeda, Y.| Danura, T.| Kass, I. S.| Morita, K.|
Published Date 2013-04-03
Publication Title Neuroscience
Volume volume235
Content Type Journal Article
Author Nishikawa, Toshio| Takaoka, Munenori| Ohara, Toshiaki| Tomono, Yasuko| Hao, Huifang| Bao, Xiaohong| Fukazawa, Takuya| Wang, Zhigang| Sakurama, Kazufumi| Fujiwara, Yasuhiro| Motoki, Takayuki| Shirakawa, Yasuhiro| Yamatsuji, Tomoki| Tanaka, Noriaki| Fujiwara, Toshiyoshi| Naomoto, Yoshio|
Published Date 2013-03
Publication Title Cancer Biology & Therapy
Volume volume14
Issue issue3
Content Type Journal Article
Author Obika, Masanari| Ogawa, Hiroko| Takahashi, Katsuyuki| Li, Jiayi| Hatipoglu, Omer Faruk| Cilek, Mehmet Zeynel| Miyoshi, Toru| Inagaki, Junko| Ohtsuki, Takashi| Kusachi, Shozo| Ninomiya, Yoshifumi| Hirohata, Satoshi|
Published Date 2012-10
Publication Title Cancer Science
Volume volume103
Issue issue10
Content Type Journal Article
Author Haga, Chiyori| Kondo, Naoki| Suzuki, Kohta| Sato, Miri| Ando, Daisuke| Yokomichi, Hiroshi| Tanaka, Taichiro| Yamagata, Zentaro|
Published Date 2012-12-13
Publication Title PLoS ONE
Volume volume7
Issue issue12
Content Type Journal Article
Author Omura, Kohei| Sakida, Shinichi| Benino, Yasuhiko| Nanba, Tokuro|
Published Date 2013-03
Publication Title Journal of Asian Ceramic Societies
Volume volume1
Issue issue1
Content Type Journal Article
Author Matsuura, Koji| Naruse, Keiji|
Published Date 2012-09-12
Publication Title Advanced Elastomers - Technology, Properties and Applications
Content Type Book
Author 岡山大学大学院教育学研究科|
Published Date 2013-07-25
Publication Title 岡山大学大学院教育学研究科研究集録
Volume volume153
Content Type Others
Author Furumatsu, Takayuki| Matsumoto, Emi| Kanazawa, Tomoko| Fujii, Masataka| Lu, Zhichao| Kajiki, Ryotaro| Ozaki, Toshifumi|
Published Date 2013-05-31
Publication Title Journal of Biomechanics
Volume volume46
Issue issue9
Content Type Journal Article
JaLCDOI 10.18926/AMO/51073
FullText URL 67_4_271.pdf
Author Hasegawa, Kenjiro| Namba, Yuzaburo| Kimata, Yoshihiro|
Abstract In the postoperative treatment of hand surgery, it is important to start exercise therapy as early as possible. In conventional negative pressure wound therapy, the fingers are immobilized by the film dressing covering the wound and hand, thereby preventing sufficient rehabilitation. Here, we devised a bag-type negative pressure wound therapy that makes it possible to start finger exercises almost immediately, and we applied it to 4 patients:one each with hand burns, symmetrical peripheral gangrene, a crush injury accompanied by extensive skin defects and a fingertip degloving injury. The duration of the bag-type negative pressure wound therapy ranged from three to eight weeks, and good granulation was achieved, so that a skin graft was not required. In addition, particularly in the case of the fingertip degloving injury, good nail regeneration was achieved. Except for the case of symmetrical peripheral gangrene, a good range of joint motion with a percent total active motion (%TAM) of 94.7% or more was achieved. Our therapy was performed by inserting the hand into a sealing bag;sufficient exercise therapy was made possible by expanding the bag during rehabilitation.
Keywords negative pressure wound therapy early exercise therapy wound healing hand surgery
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2013-08
Volume volume67
Issue issue4
Publisher Okayama University Medical School
Start Page 271
End Page 276
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2013 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 23970327
Web of Science KeyUT 000323470100010
JaLCDOI 10.18926/AMO/51072
FullText URL 67_4_265.pdf
Author Hanakawa, Hiroyuki| Orita, Yorihisa| Sato, Yasuharu| Uno, Kinya| Nishizaki, Kazunori| Yoshino, Tadashi|
Abstract We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was observed, confirming our diagnosis.
Keywords ulceration methotrexate oropharynx lymphoproliferative disorders
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2013-08
Volume volume67
Issue issue4
Publisher Okayama University Medical School
Start Page 265
End Page 269
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2013 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 23970326
Web of Science KeyUT 000323470100009
JaLCDOI 10.18926/AMO/51071
FullText URL 67_4_259.pdf
Author Idani, Hitoshi| Nakano, Kanyu| Asami, Shinya| Kubota, Tetsushi| Komoto, Satoshi| Kurose, Yohei| Kubo, Shinichiro| Nojima, Hiroki| Hioki, Katsuyoshi| Kin, Hitoshi| Takakura, Norihisa|
Abstract We describe a new simple and easy technique called the "Hook and roll technique" (HRT) that uses an articulating hook cautery to provide a critical view during single incision laparoscopic cholecystectomy (SILC). A 2-cm incision is made at the umbilicus to insert three 5-mm trocars or a multichannel port. After dissection of the serosa of the dorsal and ventral sides of the gall bladder, including Calot's triangle, the angled tip of the hook cautery is inserted between the cystic artery and duct with its tip placed dorsally. The tip is then rotated in a clockwise manner to avoid bile duct injury, allowing the connective tissue between them to be hooked, coagulated and cut. This procedure is repeated several times, followed by dissection between the cystic artery and the liver bed to achieve a critical view. From December 2008 to May 2011, 121 patients underwent SILC using HRT in our hospital without any serious complications. This technique is suitable for SILC, as it is consists of simple procedures that can be performed safely and easily, even by left hand in a cross-over approach, and it allows complete dissection of Calot's triangle to achieve a critical view without using any dissector under dangerous in-line viewing.
Keywords critical view of safety single incision laparoscopic cholecystectomy articulating hook cautery
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2013-08
Volume volume67
Issue issue4
Publisher Okayama University Medical School
Start Page 259
End Page 263
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2013 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 23970325
Web of Science KeyUT 000323470100008
JaLCDOI 10.18926/AMO/51070
FullText URL 67_4_253.pdf
Author Shiota, Yutaro| Taniguchi, Akihiko| Yuzurio, Syota| Horita, Naokatsu| Hosokawa, Shinobu| Watanabe, Yoichi| Tohmori, Hidetoshi| Ono, Tetsuya|
Abstract Dental infection can be an important source for septic pulmonary embolism (SPE), but only a few cases of SPE accompanying dental infection have been reported. The aim of this study was to characterize the clinical features of SPE induced by dental infection. Patients who fulfilled the diagnostic criteria described in the text were recruited in a retrospective fashion. All 9 patients were men, with a median age of 59 years (range:47 to 74 years). Eight patients had chest pain (88.9%), 5 had a preceding toothache (55.6%) and 3 had preceding gingival swelling (33.3%). Blood cultures obtained from 7 patients were negative. Periodontitis was found in all of the cases, periapical periodontitis in 5 cases, and gingival abscess in 3 cases. The median duration of hospitalization was 15 days, and symptoms were mild in some cases. In addition to antimicrobial therapy, tooth extraction was performed in 3 cases, tooth scaling in 6. SPE induced by dental infection has prominent clinical characteristics such as male preponderance, chest pain, preceding toothache, and mild clinical course.
Keywords bacteremia chest pain multiple nodular shadows periodontitis septic pulmonary embolism
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2013-08
Volume volume67
Issue issue4
Publisher Okayama University Medical School
Start Page 253
End Page 258
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2013 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 23970324
Web of Science KeyUT 000323470100007
JaLCDOI 10.18926/AMO/51069
FullText URL 67_4_245.pdf
Author Araki, Tohru| Monden, Koichi| Araki, Motoo|
Abstract A crossover study was conducted to identify the best α1-adrenoceptor (α1AR) antagonist for individual patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). One hundred thirteen patients (mean age 70.8 years) were enrolled. All patients met BPH clinical study guidelines. Seven agents were utilized:tamsulosin 0.2mg, silodosin 8mg, urapidil 60mg, naftopidil 50mg, prazosin 1mg, terazosin 2mg, and doxazosin 1mg. Patients were initially prescribed tamsulosin or silodosin for a week and then urapidil for a week. Two weeks later, they were prescribed the better of the 2 agents for a week and a new agent for the next week. This cycle was repeated until all 7 agents were tested. Efficacy was evaluated with the International Prostate Symptom Score. The agent rankings were doxazosin (25 [22%]), silodosin (22 [19%]), urapidil (19 [17%]), naftopidil (17 [15%]), terazosin (12 [11%]), tamsulosin (11 [10%]), prazosin (7 [6%]). Only 12 patients (11%) changed agents after the crossover study was completed. The major reason was adverse events (83%). We found that each of the 7 α1AR antagonists has its own supporters. Further, the one-week crossover study was useful in identifying the best agent for the treatment of each individual with LUTS.
Keywords alpha-1 blockers alpha1-adrenoceptor antagonists lower urinary tract symptoms benign prostatic hyperplasia crossover study
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2013-08
Volume volume67
Issue issue4
Publisher Okayama University Medical School
Start Page 245
End Page 251
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2013 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 23970323
Web of Science KeyUT 000323470100006
JaLCDOI 10.18926/AMO/51068
FullText URL 67_4_239.pdf
Author Nakamura, Shinichiro| Nouso, Kazuhiro| Kobayashi, Yoshiyuki| Shiraha, Hidenori| Ohnishi, Hideki| Toshimori, Junichi| Kuwaki, Kenji| Hagihara, Hiroaki| Takayama, Hiroki| Yamamoto, Kazuhide|
Abstract The aim of this study was to evaluate the histologic diagnosis of hypovascular hepatic lesions showing hypointensity on hepatobiliary phase images of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced MRI (EOB-MRI). In 38 patients with hepatocellular carcinoma (HCC) after curative treatments and 18 patients with liver cirrhosis, 105 hypovascular nodules that were hypointense at the hepatobiliary phase of EOB-MRI were biopsied and the clinical usefulness of these EOB-MRI findings for the diagnosis of HCC was examined. Of the 105 nodules (median diameter=12mm), 78 (74.3%), 11 (10.5%), and 16 (15.2%) were diagnosed as HCC, dysplastic, and non-neoplastic, respectively. The positive predictive value (PPV) of hypointensity at the hepatobiliary phase of EOB-MRI for the diagnosis of HCC increased to 77-90% when combined with the following factors: washout appearance on the delayed phase of triple-phase CT, hyperintensity in diffusion-weighted image of MRI, or the appearance of a hypoechoic part in ultrasonography. PPV increased to 100% when all 3 factors were positive. A relatively large proportion of hypovascular lesions that showed hypo-intensity in the hepatobiliary phase were confirmed to be HCC, and the accuracy of HCC increased when combined with other imaging findings.
Keywords hepatocellular carcinoma hypovascular diagnosis gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid magnetic resonance imaging
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2013-08
Volume volume67
Issue issue4
Publisher Okayama University Medical School
Start Page 239
End Page 244
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2013 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 23970322
Web of Science KeyUT 000323470100005
JaLCDOI 10.18926/AMO/51067
FullText URL 67_4_227.pdf
Author Ryuko, Hiromasa| Otsuka, Fumio|
Abstract Primary care physicians often encounter patients with fever of unknown origin and without apparent causes. Recent advances in laboratory medicine have facilitated diagnostic procedures;however, it is still difficult to determine the critical febrile factor at an early stage. We reviewed the medical records of 174 patients who were admitted due to a chief complaint of fever (>37.5℃) to our hospital during the period from 2004 to 2010. The patients were categorized into patients with infection, inflammation, neoplasm and drug-induced fever. Based on the analysis done by category, it was revealed that the patient's age, body temperature and duration of fever were closely related to the final diagnosis. Serum CRP levels were significantly low in the nonbacterial infection group, while serum levels of sIL-2R were high in neoplasm and drug-induced cases. CRP level on admission was weakly but significantly correlated with body temperature, while duration of fever was inversely related to body temperature. The effectiveness of PET-CT and tissue biopsy for diagnosis was considerably high, particularly in the categories of neoplasm and nonspecific inflammation, respectively, though the effectiveness of bacterial culture was low. Thus, a careful review of physical and laboratory information including body temperature, CRP level, duration of fever, gender difference and history of medication is indispensable for diagnosis. Stepwise categorization and disease classification by comprehensive and systemic checkup are very helpful for determining the causes of fever.
Keywords computed tomography (CT) C-reactive protein (CRP) fluorodeoxyglucose positron emission tomography (FDG-PET) fever of unknown origin (FUO) soluble interleukin-2 receptor (sIL-2R)
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2013-08
Volume volume67
Issue issue4
Publisher Okayama University Medical School
Start Page 227
End Page 237
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2013 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 23970321
Web of Science KeyUT 000323470100004
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/51947