result 18788 件
| Author | Uematsu, Katsutoshi| |
|---|---|
| Published Date | 2013-03-25 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| FullText URL | K0004674.pdf K0004674_honbun.pdf |
|---|---|
| Author | Watanabe, Masutaka| |
| Published Date | 2013-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第4674号 |
| Granted Date | 2013-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0004673.pdf K0004673_honbun.pdf |
|---|---|
| Author | Ishihara, Setsuko| |
| Published Date | 2013-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第4673号 |
| Granted Date | 2013-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | Yoshida, Osamu| |
|---|---|
| Published Date | 2013-03-25 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| FullText URL | K0004671.pdf K0004671_honbun.pdf |
|---|---|
| Author | Mikawa, Yasuhito| |
| Published Date | 2013-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第4671号 |
| Granted Date | 2013-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | Kuroki, Misao| Ariumi, Yasuo| Hijikata, Makoto| Ikeda, Masanori| Dansako, Hiromichi| Wakita, Takaji| Shimotohno, Kunitada| Kato, Nobuyuki| |
|---|---|
| Published Date | 2013-01-11 |
| Publication Title | Biochemical and Biophysical Research Communications |
| Volume | volume430 |
| Issue | issue2 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/50407 |
|---|---|
| FullText URL | 67_3_145.pdf |
| Author | Ishihara, Setsuko| Taira, Naruto| Kawasaki, Kensuke| Ishibe, Youichi| Mizoo, Taeko| Nishiyama, Keiko| Iwamoto, Takayuki| Nogami, Tomohiro| Motoki, Takayuki| Shien, Tadahiko| Matsuoka, Junji| Doihara, Hiroyoshi| Komoike, Yoshifumi| Sato, Shuhei| Kanazawa, Susumu| |
| Abstract | A high mammographic breast density is considered to be a risk factor for breast cancer. However, only a small number of studies on the association between breast density and lifestyle have been performed. A cross-sectional study was performed using a survey with 29 questions on life history and lifestyle. The breast density on mammography was classified into 4 categories following the BI-RADS criteria. The subjects were 522 women with no medical history of breast cancer. The mean age was 53.3 years old. On multivariate analysis, only BMI was a significant factor determining breast density in premenopausal women (parameter estimate, －0.403;p value, 0.0005), and the density decreased as BMI rose. In postmenopausal women, BMI (parameter estimate, －0.196;p value, 0.0143) and number of deliveries (parameter estimate, －0.388;p value, 0.0186) were significant factors determining breast density;breast density decreased as BMI and number of deliveries increased. Only BMI and number of deliveries were identified as factors significantly influencing breast density. BMI was inversely correlated with breast density before and after menopause, whereas the influence of number of deliveries on breast density was significant only in postmenopausal women in their 50 and 60s. |
| Keywords | breast cancer mammographic breast density life style body mass index |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-06 |
| Volume | volume67 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 145 |
| End Page | 151 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23804137 |
| Web of Science KeyUT | 000320747900003 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/50646 |
| JaLCDOI | 10.18926/AMO/50406 |
|---|---|
| FullText URL | 67_3_135.pdf |
| Author | Ueno, Hiroshi| Shoshi, Chikafumi| Suemitsu, Shunsuke| Usui, Shinichi| Sujiura, Hiroko| Okamoto, Motoi| |
| Abstract | In the phenomenon known as cross-modal plasticity, the loss of one sensory system is followed by improved functioning of other intact sensory systems. MRI and functional MRI studies suggested a role of the prefrontal cortex and the temporal lobe in cross-modal plasticity. We used a mouse model to examine the effects of sensory deprivation achieved by whisker trimming and visual deprivation achieved by dark rearing in neonatal mice on the appearance of parvalbumin (PV) neurons and the formation of glutamic acid decarboxylase 67 (GAD67)-positive puncta around pyramidal neurons in the prefrontal cortex and hippocampus. Whisker trimming, but not dark rearing, decreased the density of PV neurons in the hippocampus at postnatal day 28 (P28). In the prefrontal cortex, whisker trimming and dark rearing decreased the density of PV neurons in layer 5/6 (L5/6) at P28 and in L2/3 at P56, respectively, whereas dark rearing increased the density of PV neurons in L5/6 at P56. Whisker trimming decreased the density of GAD67-positive puncta in CA1 of the hippocampus at both P28 and P56 and in L5/6 of the prefrontal cortex at P28. Dark rearing decreased the density of GAD67-positive puncta in CA1 of the hippocampus and in both L2/3 and L5/6 of the prefrontal cortex at P28, and in L2/3 of the prefrontal cortex at P56. These results demonstrate that somatosensory or visual deprivation causes changes in the PV-interneuronal network in the mouse prefrontal cortex and hippocampus. The results also suggest that the alteration of the PV-interneuronal network, especially in the prefrontal cortex, may contribute to cross-modal plasticity. |
| Keywords | sensory deprivation parvalbumin glutamate decarboxylase (GAD67) prefrontal cortex hippocampus |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-06 |
| Volume | volume67 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 135 |
| End Page | 143 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23804136 |
| Web of Science KeyUT | 000320747900002 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/50870 |
| Author | Shiomi, Masashi| Ito, Takashi| Koike, Tomonari| Nakamura, Shun-ichi| |
|---|---|
| Published Date | 2013-04 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume29 |
| Content Type | Others |
| Author | Hirayama, Haruko| Mominoki, Katsumi| Shiina, Takahiko| Shimizu, Yasutake| |
|---|---|
| Published Date | 2013-04 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume29 |
| Content Type | Others |
| FullText URL | O0004390.pdf O0004390_honbun.pdf |
|---|---|
| Author | Matsusita, Kouki| |
| Published Date | 2012-12-31 |
| Content Type | Thesis or Dissertation |
| Grant Number | 乙第4390号 |
| Granted Date | 2012-12-31 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | Ono, Naoki| |
|---|---|
| Published Date | 2012-12-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| FullText URL | O0004388.pdf O0004388_honbun.pdf |
|---|---|
| Author | Hanayama, Yoshihisa| |
| Published Date | 2012-12-31 |
| Content Type | Thesis or Dissertation |
| Grant Number | 乙第4388号 |
| Granted Date | 2012-12-31 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | Nakatuka, Atsuko| |
|---|---|
| Published Date | 2012-12-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Iwato, Eiji| |
|---|---|
| Published Date | 2012-12-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| FullText URL | O0004385.pdf O0004385_honbun.pdf |
|---|---|
| Author | Hujinaka, Wazou| |
| Published Date | 2012-12-31 |
| Content Type | Thesis or Dissertation |
| Grant Number | 乙第4385号 |
| Granted Date | 2012-12-31 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0004670.pdf K0004670_honbun.pdf |
|---|---|
| Author | Fatmawati, Ni Nengah Dwi| |
| Published Date | 2012-12-31 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第4670号 |
| Granted Date | 2012-12-31 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | Shimoura, Yasumasa| |
|---|---|
| Published Date | 2012-12-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Takamiya, Motonori| |
|---|---|
| Published Date | 2012-12-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Hujiwara, Miyuki| |
|---|---|
| Published Date | 2012-12-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
