result 18634 件
Author | Nakao, Miyuki| |
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Published Date | 2012-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume124 |
Issue | issue2 |
Content Type | Journal Article |
Author | Yagi, Takahito| |
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Published Date | 2012-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume124 |
Issue | issue2 |
Content Type | Journal Article |
Author | Doihara, Hiroyoshi| |
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Published Date | 2012-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume124 |
Issue | issue2 |
Content Type | Journal Article |
Author | Hayashi, Keiichiro| Ohmori, Iori| Matsui, Hideki| |
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Published Date | 2012-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume124 |
Issue | issue2 |
Content Type | Journal Article |
Author | Wang, Feifei| Yasuhara, Takao| Kameda, Masahiro| Date, Isao| |
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Published Date | 2012-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume124 |
Issue | issue2 |
Content Type | Journal Article |
Author | Sasaki, Tsuyoshi| Tazawa, Hiroshi| Hasei, Jo| Kunisada, Toshiyuki| Yoshida, Aki| Hashimoto, Yuuri| Yano, Shuya| Yoshida, Ryosuke| Uno, Futoshi| Kagawa, Shunsuke| Morimoto, Yuki| Urata, Yasuo| Fujiwara, Toshiyoshi| Ozaki, Toshifumi| |
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Published Date | 2012-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume124 |
Issue | issue2 |
Content Type | Journal Article |
Author | Fujimura, Atsushi| Tomizawa, Kazuhito| Matsui, Hideki| |
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Published Date | 2012-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume124 |
Issue | issue2 |
Content Type | Journal Article |
JaLCDOI | 10.18926/AMO/48569 |
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FullText URL | 66_3_285.pdf |
Author | Mizobuchi, Satoshi| Matsuoka, Yoshikazu| Obata, Norihiko| Kaku, Ryuji| Itano, Yoshitaro| Tomotsuka, Naoto| Taniguchi, Arata| Nishie, Hiroyuki| Kanzaki, Hirotaka| Ouchida, Mamoru| Morita, Kiyoshi| |
Abstract | Perioperative beta-blocker administration has recently been recommended for patients undergoing cardiac or other surgery due to the beneficial cardiovascular effects of these agents. In addition, some studies have reported that perioperatively administered beta-blockers also have analgesic effects. In this study, to investigate the antinociceptive effects and the analgesic profile of landiolol, we examined the effects of intrathecal landiolol administration on nociceptive pain behavior and c-fos mRNA expression (a neural marker of pain) in the spinal cord using a rat formalin model. We found that pain-related behavior was inhibited by intrathecal landiolol administration. Moreover, the increase in c-fos mRNA expression on the formalin-injected side was less pronounced in rats administered landiolol than in saline administered controls. Thus, intrathecal administration of landiolol exhibited antinociceptive effects. Further investigation of the antinociceptive mechanism of landiolol is required. |
Keywords | beta-blocker landiolol formalin pain behavior c-fos |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2012-06 |
Volume | volume66 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 285 |
End Page | 289 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 22729110 |
Web of Science KeyUT | 000305669700013 |
Author | Kanazawa, Tomoko| |
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Published Date | 2012-03-23 |
Publication Title | |
Content Type | Thesis or Dissertation |
FullText URL | K0004505.pdf K004505_honbun.pdf |
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Author | Takahata, Yoko| |
Published Date | 2012-03-23 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第4505号 |
Granted Date | 2012-03-23 |
Thesis Type | Doctor of Philosophy in Medical Science |
Grantor | 岡山大学 |
language | Japanese English |
Author | Takahashi, Noriko| |
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Published Date | 2012-03-23 |
Publication Title | |
Content Type | Thesis or Dissertation |
Author | Ibrahim, Juliani| |
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Published Date | 2012-03-23 |
Publication Title | |
Content Type | Thesis or Dissertation |
Author | Ma, Shaobo| |
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Published Date | 2012-03-23 |
Publication Title | |
Content Type | Thesis or Dissertation |
FullText URL | K0004501.pdf K004501_honbun.pdf |
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Author | Zhang, Kai| |
Published Date | 2012-03-23 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第4501号 |
Granted Date | 2012-03-23 |
Thesis Type | Doctor of Philosophy in Medical Science |
Grantor | 岡山大学 |
language | Japanese English |
Author | Miyake, Yoshiaki| |
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Published Date | 2012-03-23 |
Publication Title | |
Content Type | Thesis or Dissertation |
Author | Takata, Naoki| |
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Published Date | 2012-03-23 |
Publication Title | |
Content Type | Thesis or Dissertation |
Author | Nawata, Miho| |
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Published Date | 2012-03-23 |
Publication Title | |
Content Type | Thesis or Dissertation |
Author | Okubo, Sayuri| |
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Published Date | 2012-03-23 |
Publication Title | |
Content Type | Thesis or Dissertation |
Author | Jin, Yu| |
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Published Date | 2012-03-23 |
Publication Title | |
Content Type | Thesis or Dissertation |
Author | Mori, Kyoko| |
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Published Date | 2012-03-23 |
Publication Title | |
Content Type | Thesis or Dissertation |